Sugo Noriyuki 菅生紀之

… Alternative Names

SUGO Noriyuki 菅生紀之

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Researcher Number	20372625
Other IDs
Affiliation (Current)	2026: 神奈川大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪大学, 大学院生命機能研究科, 特任准教授(常勤) 2018 – 2021: 大阪大学, 生命機能研究科, 特任准教授(常勤) 2011 – 2017: 大阪大学, 生命機能研究科, 助教 2015: 大阪大学, 大学院生命機能研究科, 助教 2012 – 2013: 大阪大学, 大学院・生命機能研究科, 助教 … More 2007 – 2010: Osaka University, Graduate School of Frontier Bioscienoes, Assistant Professor 2008: Osaka University, 生命機能研究科, 助教 2006: 大阪大学, 大学院生命機能研究科, 助手 2004 – 2005: 大阪大学, 大学院・生命機能研究科, 特任助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology / Biological Sciences / Neurochemistry/Neuropharmacology / Nanomaterials/Nanobioscience / Neuroscience in general Except Principal Investigator Neuroscience in general / Basic Section 59040:Nutrition science and health science-related / Basic Section 46010:Neuroscience-general-related / Biological Sciences / Neurophysiology / General neuroscience / Neuroscience in general
Keywords	Principal Investigator DNA修復 / 分子・細胞・神経生物学 / 神経科学 / 発生・分化 / 大脳皮質 / クロマチン / 神経細胞 / 神経細胞分化 / 1分子イメージング / １分子イメージング … More / 転写 / ナノバイオ / 発現制御 / 脳・神経 / 発生・分化・老化 / 1分子生理・生化学 / 分子・細胞神経科学 / ゲノム / ビタミンC / エピゲノム / DNA脱メチル化 / DNAメチル化・脱メチル化 / 突然変異 / 神経発生・分化 / 分子・脳・神経生物学 / エピジェネティクス / DNA損傷 / 神経活動 / 遺伝子発現制御 / 神経活動依存的 / DNA 修復 / 遺伝子発現調節 / 転写因子 / 神経発生 / ノックアウトマウス … More Except Principal Investigator 神経活動 / 大脳 / 視床 / 軸索分岐 / 大脳皮質 / 神経活動依存性 / RhoA / 軸索誘導 / 遺伝子発現 / ネトリン / 神経回路 / 軸索 / 樹状突起 / 層特異性 / 突然変異 / 神経細胞死 / 神経精神疾患 / 精神神経疾患 / エピゲノム / 神経発生発達 / DNA脱メチル化 / Slc23a2 / ビタミンCトランスポーター / ビタミンC / 刺激生理学 / 光遺伝学 / 転写調節 / ヒト / ヒトニューロン / プロモーター活性 / １分子イメージング / BDNF / CBP / CREB / 受容体 / 視床由来分子 / netrin-4 / Unc5B / 水平軸索 / 細胞骨格 / RhoGEF / neural activity / layer / axon branching / thalamus / neocorex / 層構造 / 軸索枝分かれ / セマフォリン / シナプス / シナプス形成 / エンドサイトーシス / 標的由来因子 / 分岐 / 軸索分枝 / Kir2.1 / 同期性 / 核細胞質移動 / c-fos / 遺伝子発現調節 / HDAC9 Less

神経細胞の能動的DNA脱メチル化による大脳形成メカニズムの解明Principal Investigator
- Principal Investigator
  
  菅生紀之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Osaka University
Effect of vitamin C on neural development of the cerebral cortex.
- Principal Investigator
  
  Higuchi Mayumi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka University
Mutagenesis in cortical developmentPrincipal Investigator
- Principal Investigator
  
  Sugo Noriyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Osaka University
Dynamics of neuronal activity-dependent gene expression
- Principal Investigator
  
  Yamamoto Nobuhiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Osaka University
Single Molecule Imaging of Transcription Dynamics in Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  Sugo Noriyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
A study of DNA repair dynamics during neuronal differentiation using single-molecule imagingPrincipal Investigator
- Principal Investigator
  
  SUGO Noriyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Cytoskeleton mechanisms of activity-dependent axon branching
- Principal Investigator
  
  YAMAMOTO Nobuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Osaka University
A study of neuronal activity-dependent transcription factor dynamics using single-molecule imagingPrincipal Investigator
- Principal Investigator
  
  SUGO Noriyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
脳形成における細胞移動とクロマチン動態のイメージング解析Principal Investigator
- Principal Investigator
  
  菅生紀之
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
A study of the molecular mechanism underlying activity-dependent thalamocortical axon branching
- Principal Investigator
  
  YAMAMOTO NOBUHIKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka University
Chromatin Dynamics Associated with Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  SUGO Noriyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Axon branch remodeling mechanisms in mesoscopic neuronal circuit formation
- Principal Investigator
  
  YAMAMOTO Nobuhiko
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Chromatin Dynamics during Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  SUGO Noriyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Dynamics of Nuclear Architecture and Genome Organization during Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  SUGO Noriyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Osaka University
The Mechanism Underlying the Formation of Activity-Dependent Thalamocortical Projection
- Principal Investigator
  
  YAMAMOTO Nobuhiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka University
A study of target recognition and axon branching m hanisms in the thalamomrocalpmjection
- Principal Investigator
  
  YAMAMOTO Nobuhiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka University
DNA修復遺伝子ノックアウトマウスによる大脳皮質細胞の発生・分化制御機構の解析Principal Investigator
- Principal Investigator
  
  菅生紀之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka University

[Book] Live-Cell Single-Molecule Imaging with Optogenetics Reveals Dynamics of a Neuronal Activity-Dependent Transcription Factor. In: Yamamoto N., Okada Y. (eds) Single Molecule Microscopy in Neurobiology. Neuromethods, vol 1542020
- Author(s)
  Kitagawa H., Sugo N., Yamamoto N
- Total Pages
  20
- Publisher
  Humana, New York, NY
- ISBN
  9781071605318
- Data Source
  KAKENHI-PROJECT-17K07109
[Journal Article] Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons2020
- Author(s)
  Uyeda A, Onishi K, Hirayama T, Hattori S, Miyakawa T, Yagi T, Yamamoto N, Sugo N.
- Journal Title
  
  J Neurosci.
  
  Volume: 40 Issue: 47 Pages: 9012-9027
- DOI
  10.1523/jneurosci.0319-20.2020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01976, KAKENHI-PROJECT-17K07109, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-16H06460, KAKENHI-PROJECT-19H03325
[Journal Article] Suppression of DSB Formation by Polβ in Active DNA Demethylation is Required for Postnatal Hippocampal Development2019
- Author(s)
  Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto, Noriyuki Sugo
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/852053
- Open Access
- Data Source
  KAKENHI-PROJECT-17K07109
[Journal Article] Activity-dependent dynamics of the transcription factor CREB in cortical neurons revealed by single-molecule imaging2017
- Author(s)
  Kitagawa H, Sugo N, Morimatsu M, Arai Y, Yanagida T, Yamamoto N
- Journal Title
  
  J Neurosci
  
  Volume: 37 Issue: 1 Pages: 1-10
- DOI
  10.1523/jneurosci.0943-16.2017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01436, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-15K14350, KAKENHI-PROJECT-15K14318
[Journal Article] Immunocytochemistry and fluorescence imaging efficiently identify individual neurons with CRISPR/Cas9-mediated gene disruption in primary cortical cultures2017
- Author(s)
  Hiroto Tsunematsu, Akiko Uyeda, Nobuhiko Yamamoto, Noriyuki Sugo
- Journal Title
  
  BMC Neuroscience
  
  Volume: 18 Issue: 1 Pages: 55-55
- DOI
  10.1186/s12868-017-0377-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07109, KAKENHI-PLANNED-16H06460, KAKENHI-PUBLICLY-17H05569, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-15K14350
[Journal Article] Genome Stability by DNA polymerase β in Neural Progenitors Contributes Neuronal Differentiation in Cortical Development2017
- Author(s)
  Kohei Onishi, Akiko Uyeda, Mistuhiro Shida, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto, Noriyuki Sugo
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 37 Issue: 35 Pages: 8444-8485
- DOI
  10.1523/jneurosci.0665-17.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07109, KAKENHI-PLANNED-16H06460, KAKENHI-PUBLICLY-17H05569, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-15K14350, KAKENHI-PROJECT-17K01976, KAKENHI-PROJECT-26350980
[Journal Article] Nucleocytoplasmic Shuttling of Histone Deacetylase 9 Controls Activity-Dependent Thalamocortical Axon Branching2017
- Author(s)
  Ricardo Alchini, Haruka Sato, Naoyuki Matsumoto, Tomomi Shimogori, Noriyuki Sugo, Nobuhiko Yamamoto
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 6024-6024
- DOI
  10.1038/s41598-017-06243-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07109, KAKENHI-PLANNED-16H06460, KAKENHI-PUBLICLY-17H05569, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-14J00332, KAKENHI-PROJECT-15K14350
[Journal Article] Synapse-dependent and independent mechanisms of thalamocortical axon branching are regulated by neuronal activity2016
- Author(s)
  Matsumoto, N., Hoshiko, M., Sugo, N., Fukazawa, Y. & Yamamoto, N.
- Journal Title
  
  Developmental Neurobiology
  
  Volume: 76 Issue: 3 Pages: 323-336
- DOI
  10.1002/dneu.22317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14318, KAKENHI-PLANNED-23115102, KAKENHI-PUBLICLY-15H01436, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-15H06369
[Journal Article] Visualization of HDAC9 spatiotemporal subcellular localization in primary neuron cultures2016
- Author(s)
  Sugo N, Yamamoto N
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1436 Pages: 119-127
- DOI
  10.1007/978-1-4939-3667-0_9
- ISBN
  9781493936656, 9781493936670
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01436, KAKENHI-PROJECT-15H04260, KAKENHI-PLANNED-16H06460, KAKENHI-PROJECT-15K14318
[Journal Article] Single-molecule imaging reveals dynamics of CREB transcription factor bound to its target sequence2015
- Author(s)
  Sugo, N., Morimatsu, M., Arai, Y., Kousoku, Y., Ohkuni, A., Nomura, T., Yanagida, T. & Yamamoto, N.
- Journal Title
  
  Scientific Report
  
  Volume: 5 Issue: 1 Pages: 10662-10662
- DOI
  10.1038/srep10662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14318, KAKENHI-PROJECT-15K14350, KAKENHI-PLANNED-23115102, KAKENHI-PUBLICLY-15H01436, KAKENHI-PROJECT-15H04260, KAKENHI-PROJECT-25640035
[Journal Article] Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling2013
- Author(s)
  Granseth B, Fukushima Y, Sugo N, Lagnado L, Yamamoto N
- Journal Title
  
  Front Neural Circuits
  
  Volume: 7 Pages: 202-202
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23115102
[Journal Article] Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling2013
- Author(s)
  Granseth B, Fukushima Y, Sugo N, Lagnado L, Yamamoto N
- Journal Title
  
  Frontier in Neural Circuits
  
  Volume: 7 Pages: 202-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300118
[Journal Article] Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling2013
- Author(s)
  Bjorn Granseth, Yuichi Fukushima, Noriuki Sugo, Leon Lagnado and Nobuhiko Yamamoto
- Journal Title
  
  Frontiers in Neural Circuits
  
  Volume: 7 Pages: 202-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640035
[Journal Article] Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling2013
- Author(s)
  Granseth B, Fukushima Y, Sugo N, Lagnado L, Yamamoto N
- Journal Title
  
  Front Neural Circuits
  
  Volume: 7 Pages: 202-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300118
[Journal Article] A molecular mechanism that regulates medially oriented axonal growth of upper layer neurons in the developing neocortex.2011
- Author(s)
  Zhao H, Maruyama T, Hattori Y, Sugo N, Takamatsu H, Kumanogoh A, Shirasaki R, Yamamoto N
- Journal Title
  
  J Comp Neurol 519
  
  Pages: 834-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300110
[Journal Article] A molecular mechanism that regulates medially oriented axonal growth of upper layer neurons in the developing neocortex2011
- Author(s)
  Zhao H, Maruyama T, Hattori Y, Sugo N, Takamatsu H, Kumanogoh A, Shirasaki R, Yamamoto N
- Journal Title
  
  J Comp Neurol
  
  Volume: 519 Pages: 834-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300118
[Journal Article] A Molecular Mechanism That Regulates Medially Oriented Axonal Growth of Upper Layer Neurons in the Developing Neocortex.2011
- Author(s)
  Hong Zhao, Takuro Maruyama, Yuki Hattori, Noriyuki Sugo, Hyota Takamatsu, Atsushi Kumanogoh, Ryuichi Shirasaki, Nobuhiko Yamamoto
- Journal Title
  
  J Comp Neurol. 519
  
  Pages: 834-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200009
[Journal Article] A Molecular Mechanism That Regulates Medially Oriented Axonal Growth of Upper Layer Neurons in the Developing Neocortex.2011
- Author(s)
  Hong Zhao, Takuro Maruyama, Yuki Hattori, Noriyuki Sugo, Hyota Takamatsu, Atsushi Kumanogoh, Ryuichi Shirasaki, Nobuhiko Yamamoto.
- Journal Title
  
  J Comp Neurol. 519
  
  Pages: 834-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700404
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons2010
- Author(s)
  Noriyuki Sugo, et al.
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 31 Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200009
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons.2010
- Author(s)
  Sugo N, Oshiro H, Takemura M, Kobayashi T, Kohno Y, Uesaka N, Song WJ, Yamamoto N
- Journal Title
  
  Eur J Neurosci 31
  
  Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300110
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons.2010
- Author(s)
  Sugo N, Oshiro H, Takemura M, Kobayashi T, Kohno Y, Uesaka N, Song W-J, Yamamoto N
- Journal Title
  
  Eur J Neurosci (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300110
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons.2010
- Author(s)
  Noriyuki Sugo, Hiroaki Oshiro, Mitsuhiro Takemura, Toshiaki Kobayashi, Yusuke Kohno, Naofumi Uesaka, Wen-Jie Song, Nobuhiko Yamamoto.
- Journal Title
  
  Eur J Neurosci. 31
  
  Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700404
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons2010
- Author(s)
  Noriyuki Sugo, et al.
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 31 Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700404
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons.2010
- Author(s)
  Sugo N, Oshiro H, Takemura M, Kobayashi T, Kohno Y, Uesaka N, Song W-J, Yamamoto N
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 31 Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300110
[Journal Article] Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons.2010
- Author(s)
  Noriyuki Sugo, Hiroaki Oshiro, Mitsuhiro Takemura, Toshiaki Kobayashi, Yusuke Kohno, Naofumi Uesaka, Wen-Jie Song, Nobuhiko Yamamoto
- Journal Title
  
  Eur J Neurosci. 31
  
  Pages: 1521-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200009
[Journal Article] p53 deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase β-deficient mice2004
- Author(s)
  Noriyuki Sugo, et al.
- Journal Title
  
  Molecular and Cellular Biology 24
  
  Pages: 9470-9477
- Data Source
  KAKENHI-PROJECT-16700286
[Presentation] 神経前駆細胞内へのビタミンC取り込みは神経発生における能動的DNA脱メチル化を制御する2024
- Author(s)
  水野紗矢、榊琉維、馬渕博基、神吉暁、樋口真弓、三浦史仁、荒木啓充、荒木喜美、八木健、菅生紀之
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-24K09644
[Presentation] 神経前駆細胞内へのビタミンC取り込みは神経発生における能動的DNA脱メチル化を制御する2024
- Author(s)
  水野紗矢、榊琉維、馬渕博基、神吉暁、樋口真弓、三浦史仁、荒木啓充、荒木喜美、八木健、菅生紀之
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11775
[Presentation] 大脳神経発生においてビタミンCはDNAポリメラーゼβ依存能動的DNA脱メチル化とゲノム安定性を調節する2024
- Author(s)
  菅生紀之、水野紗矢、榊琉維、馬渕博基、神吉暁、樋口真弓、三浦史仁、荒木啓充、荒木喜美、八木健
- Organizer
  NEURO2024 第47回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-24K09644
[Presentation] 大脳神経発生においてビタミンCはDNAポリメラーゼβ依存能動的DNA脱メチル化とゲノム安定性を調節する2024
- Author(s)
  菅生紀之、水野紗矢、榊琉維、馬渕博基、神吉暁、樋口真弓、三浦史仁、荒木啓充、荒木喜美、八木健
- Organizer
  NEURO2024 第47回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K11775
[Presentation] 大脳皮質の神経発生においてビタミンCSlc23a2はPolポリメラーゼβ依存的DNA脱メチル化経路を調整する2023
- Author(s)
  菅生紀之, 馬渕博基, 樋口真弓, 荒木喜美, 八木健
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K11775
[Presentation] 大脳皮質の神経発生においてビタミンCトランスポーターSlc23a2はDNAポリメラーゼβ依存的DNA脱メチル化経路を調節する2023
- Author(s)
  菅生紀之, 馬渕博基, 樋口真弓, 荒木喜美, 八木健
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] 大脳神経前駆細胞においてビタミンCはPolβ依存的能動的DNA脱メチル化を調整しゲノム安定性に寄与する2023
- Author(s)
  神吉暁, 馬渕博基, 樋口真弓, 荒木喜美, 八木健, 菅生紀之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] 大脳神経前駆細胞においてビタミンCはPolβ依存的能動的DNA脱メチル化を調整しゲノム安定性に寄与する2023
- Author(s)
  神吉暁, 馬渕博基, 樋口真弓, 荒木喜美, 八木健, 菅生紀之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11775
[Presentation] ヒト由来大脳皮質ニューロンにおいてCREBと共因子の時空間的な動態が神経活動依存的な遺伝子発現を制御する2022
- Author(s)
  渥美友梨、菅生紀之、岩田亮平、Pierre Vanderhaeghen 、山本亘彦
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] ヒト由来大脳皮質神経細胞において共因子を伴ったCREBの動態変化が神経活動依存的に転写を促進する2022
- Author(s)
  渥美友梨，菅生紀之，岩田亮平，Pierre Vanderhaeghen，山本亘彦
- Organizer
  第15回神経発生討論会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] DNAポリメラーゼβ欠損は大脳皮質神経細胞の発生において体細胞突然を誘発させる2022
- Author(s)
  菅生紀之、松本理沙、中山宙、松本敏幸、藤本翔太、佐藤康成、若山清香、若山照彦、内村有邦、八木健
- Organizer
  NEURO2022 第45回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] ヒトiPS細胞由来大脳オルガノイドの神経発生においてDNAポリメラーゼβ欠損はDNA２本鎖切断を引き起こす2022
- Author(s)
  菅生紀之
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] Spatiotemporal dynamics of CREB with cofactors regulate activity-dependent gene expression in human cortical neurons2022
- Author(s)
  Yuri Atsumi, Noriyuki Sugo, Hiroshi Kimura, Ryohei Iwata, Pierre Vanderhaeghen, Nobuhiko Yamamoto
- Organizer
  Cortical development and plasticity of the Brain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] ヒト由来大脳皮質神経細胞における転写調節因子CREBと共因子CBPの神経活動依存的な動態 (Activity-dependent dynamics of the transcription factor CREB via cofactor CBP in human cortical-like neurons)2021
- Author(s)
  渥美友梨，菅生紀之，岩田亮平，Pierre Vanderhaeghen，山本亘彦
- Organizer
  第43回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] 体細胞核由来クローンES細胞の全ゲノム解析によるDNAポリメラーゼβ欠損マウス大脳皮質神経細胞の突然変異解析2021
- Author(s)
  松本理沙, 中山宙, 松本敏幸, 藤本翔太, 佐藤康成, 若山清香, 若山照彦, 内村有邦, 八木健, 菅生紀之
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] ctivity-dependent dynamics of CREB via cofactor CBP in human cortical neurons2021
- Author(s)
  Atsumi Y, Sugo N, Iwata R, Vanderhaeghen P, Yamamoto N
- Organizer
  The 44th Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] ヒト由来大脳皮質神経細胞における転写調節因子CREBの共因子CBPを介した神経活動依存的な動態変化 (Activity-dependent dynamics of the transcription factor CREB via cofactor CBP in human cortical-like neurons)2021
- Author(s)
  渥美友梨，菅生紀之，岩田亮平，Pierre Vanderhaeghen，山本亘彦
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] ヒトiPS細胞由来大脳オルガノイドにおいてDNAポリメラーゼβ欠損は神経前駆細胞にDNA2本鎖切断を引き起こす2021
- Author(s)
  千葉清歌、増田光起、恒松大翔、黒沢綾、足立典隆、山本亘彦、八木健、菅生紀之
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] ヒトiPS細胞由来大脳オルガノイドにおいてDNAポリメラーゼβ欠損は神経前駆細胞にDNA2本鎖切断を引き起こす2021
- Author(s)
  千葉清歌、増田光起、恒松大翔、黒沢綾、足立典隆、山本亘彦、八木健、菅生紀之
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] 体細胞核由来クローンES細胞の全ゲノム解析によるDNAポリメラーゼβ欠損マウス大脳皮質神経細胞の突然変異解析2021
- Author(s)
  松本理沙, 中山宙, 松本敏幸, 藤本翔太, 佐藤康成, 若山清香, 若山照彦, 内村有邦, 八木健, 菅生紀之
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] 大脳皮質神経細胞においてビタミンCトランスポーターSlc23a2の過剰発現は能動的DNA脱メチル化を介してDNA２本鎖切断を誘発する2020
- Author(s)
  藤本翔太、松本敏幸、植田尭子、山本亘彦、八木健、菅生紀之
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] DNA polymerase β contributes to genome stability in developing cortical neurons2020
- Author(s)
  菅生紀之
- Organizer
  遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」
- Data Source
  KAKENHI-PROJECT-20K06854
[Presentation] Single-molecule imaging of the activity-dependent transcription factor CREB in human cortical-like neurons2020
- Author(s)
  Atsumi Y, Sugo N, Iwata, R, Vanderhaeghen P, Yamamoto N
- Organizer
  The 43rd Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] Activity-dependent dynamics of the transcription factor CREB in human cortical-like neurons: A study using single-molecule imaging2020
- Author(s)
  Atsumi Y, Sugo N, Iwata R, Vanderhaeghen P, Yamamoto N
- Organizer
  FENS 2020 Virtual Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] Single-molecule imaging of CREB transcription factor in human cortical-like neurons2019
- Author(s)
  Atsumi, Y., Sugo, N., Iwata, R., Vanderhaeghen, P., Yamamoto, N.
- Organizer
  The 10th IBRO World Congress of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] The involvement of reactive glial cells in the formation of ectopic corticofugal projections after cortical ablation2019
- Author(s)
  Chang, L., Sugo, N., Yamamoto, N.
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03325
[Presentation] Single-molecule imaging of CREB transcriptionfactor in human cortical-like neurons2019
- Author(s)
  Yuri Atsumi, Noriyuki Sugo, Ryohei Iwata,Pierre Vanderhaeghen, Nobuhiko Yamamoto
- Organizer
  IBRO 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] DNA polymerase β is required for postnatal hippocampal development and function2018
- Author(s)
  Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
- Organizer
  Cold Spring Harbor Asia meeting on Latest Advance in Development & Function of Neuronal Circuit
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] Genome Stability by DNA polymerase β in Cortical Development2018
- Author(s)
  菅生紀之
- Organizer
  第41回日本神経科学大会シンポジウム「大脳皮質の形成と機能発現を担う遺伝子制御システムの新展開」
- Invited
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] Involvement of Polβ in postnatal neuronal development and function via active DNA demethylation2018
- Author(s)
  Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
- Organizer
  国立遺伝学研究所研究会「哺乳類脳の機能的神経回路の構築メカニズム」
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] Maintenance of genome stability by DNA polymerase β in necessary for postnatal development in cortical and hippocampal neurons2018
- Author(s)
  Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] iPS細胞を利用したヒト神経発生過程におけるDNAポリメラーゼ βの機能解析2017
- Author(s)
  恒松大翔、菅生紀之、黒沢綾、足立典隆、山本亘彦
- Organizer
  第４０回日本神経科学大会（舞浜）
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] DNA polymerase β is required for active DNA demethylation in postnatal development of cortical neurons2017
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi1 and Nobuhiko Yamamoto
- Organizer
  第48回生理研国際シンポジウム（岡崎）
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] 神経活動依存的な転写因子動態の１分子蛍光イメージンング解析2017
- Author(s)
  菅生紀之
- Organizer
  第６９回日本細胞生物学会シンポジウム「クラップ＆ビルド・システムによる神経制御」（仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] 大脳皮質神経細胞分化におけるDNAポリメラーゼβによるゲノム恒常性維持2017
- Author(s)
  菅生紀之、大西公平、植田尭子、至田充宏、平山晃斉、八木健、山本亘彦
- Organizer
  第３９回神経組織培養研究会（名古屋）
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] 神経活動依存的な転写因子動態の１分子蛍光イメージンング解析2017
- Author(s)
  菅生紀之
- Organizer
  第６９回日本細胞生物学会シンポジウム「クラップ＆ビルド・システムによる神経制御」（仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] Genome stability by DNA polymerase β is Critical for Neuronal Differentiation in Cortical Development2017
- Author(s)
  Noriyuki Sugo, Kohei Onishi, Akiko Uyeda, Mistuhiro Shida, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  Gene regulatory mechanisms in neural fate decisions (San Juan de Alicante, Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] A study of the role of DNA polymerase β in human brain development using induced pluripotent stem cells2017
- Author(s)
  Tsunematsu H, Sugo N, Kurosawa A, Adachi N, Yamamoto N
- Organizer
  The 40th Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] iPS細胞を利用したヒト神経発生過程におけるDNAポリメラーゼ βの機能解析2017
- Author(s)
  恒松大翔、菅生紀之、黒沢綾、足立典隆、山本亘彦
- Organizer
  第４０回日本神経科学大会（舞浜）
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] The role of neuronal activity and co-factors in CREB dynamics in cortical neurons: A single-molecule imaging study2017
- Author(s)
  Kitagawa H, Sugo N, Yamamoto N
- Organizer
  Cortical Development Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] DNA polymerase β is involved in active DNA demethylation during postnatal development of cortical neurons2017
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi1 and Nobuhiko Yamamoto
- Organizer
  遺伝研研究会：哺乳類脳の機能的神経回路の構築メカニズム（三島）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] 生後発達期の大脳皮質ニューロンにおけるDNAポリメラーゼβの役割2017
- Author(s)
  植田尭子、菅生紀之、大西公平、平山晃斉、八木健、山本亘彦
- Organizer
  第４０回日本神経科学大会（舞浜）
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase β is required for active DNA demethylation in postnatal development of cortical neurons2017
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi1 and Nobuhiko Yamamoto
- Organizer
  第48回生理研国際シンポジウム（岡崎）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase β is involved in active DNA demethylation during postnatal development of cortical neurons2017
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi1 and Nobuhiko Yamamoto
- Organizer
  遺伝研研究会哺乳類脳の機能的神経回路の構築メカニズム（三島）
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] 大脳皮質神経細胞分化におけるDNAポリメラーゼβによるゲノム恒常性維持2017
- Author(s)
  菅生紀之、大西公平、植田尭子、至田充宏、平山晃斉、八木健、山本亘彦
- Organizer
  第３９回神経組織培養研究会（名古屋）
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] The role of DNA polymerase β in postnatal cortical neuron development2017
- Author(s)
  Uyeda A, Sugo N, Onishi K, Lyu J, Hirayama T, Yagi T, Yamamoto N
- Organizer
  The 40th Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] 生後発達期の大脳皮質ニューロンにおけるDNAポリメラーゼβの役割2017
- Author(s)
  植田尭子、菅生紀之、大西公平、平山晃斉、八木健、山本亘彦
- Organizer
  第４０回日本神経科学大会（舞浜）
- Data Source
  KAKENHI-PROJECT-17K07109
[Presentation] Genome stability by DNA polymerase β is Critical for Neuronal Differentiation in Cortical Development2017
- Author(s)
  Noriyuki Sugo, Kohei Onishi, Akiko Uyeda, Mistuhiro Shida, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  Gene regulatory mechanisms in neural fate decisions (San Juan de Alicante, Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] 神経前駆細胞におけるDNAポリメラーゼ βによるゲノム恒常性維持が発生期大脳皮質の神経細胞分化に必要である2017
- Author(s)
  大西公平、菅生紀之、植田尭子、至田充宏、平山晃斉、八木健、山本亘彦
- Organizer
  第６４回日本生化学会近畿支部例会（大阪）
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Genome integrity maintained by DNA polymerase b in neural progenitors is required for postmitotic neuronal development2016
- Author(s)
  Kohei Onishi, Akiko Uyeda, Mitsuhiro Shida, Noriyuki Sugo, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  Circuit Construction in the Mammalian Brain
- Place of Presentation
  大阪府・吹田市
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] １分子蛍光イメージングによる転写因子CREBの神経活動依存的動態の解析2016
- Author(s)
  菅生紀之
- Organizer
  日本発生生物学会秋季シンポジウム
- Place of Presentation
  静岡県・三島市
- Year and Date
  2016-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase β function in neural progenitors is required for postmitotic neuronal survival and differentiation in the developing cortex2016
- Author(s)
  Kohei Ohnishi, Noriyuki Sugo, Shunsuke Toyoda, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  The 39th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] Single-Molecule imaging reveals activity-dependent dynamics of the transcription factor CREB in cortical neurons2016
- Author(s)
  Hironobu Kitagawa, Noriyuki Sugo, Nobuhiko Yamamoto
- Organizer
  Circuit Construction in the Mammalian Brain
- Place of Presentation
  大阪府・吹田市
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Maintaining Genome Integrity by DNA polymerase beta in Neural Progenitors is Critical for Postmitotic Neuronal Development2016
- Author(s)
  Noriyuki Sugo, Kohei Onishi, Akiko Uyeda, Mistuhiro Shida, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  The Brain Mosaic, cellular heterogeneity in the CNS
- Place of Presentation
  Leuven, Belgium
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase b is required for maintaining genome stability in postnatal cortical development2016
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  Circuit Construction in the Mammalian Brain
- Place of Presentation
  大阪府・吹田市
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Involvement of DNA polymerase beta in postnatal development of cortical neurons2016
- Author(s)
  Akiko Uyeda, Noriyuki Sugo, Kohei Onishi, Shunsuke Toyoda, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  第３９回日本神経科学大会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase beta function in neural progenitors is required for postmitotic neuronal survival and differentiateon in the developing cortex2016
- Author(s)
  Kohei Onishi, Noriyuki Sugo, Akiko Uyeda, Shunsuke Toyoda, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto
- Organizer
  第３９回日本神経科学大会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Genome maintenance by DNA polymerase β in neural progenitors is critical for postmitotic neuronal development2016
- Author(s)
  Noriyuki Sugo
- Organizer
  Circuit Construction in the Mammalian Brain
- Place of Presentation
  大阪府・吹田市
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Activity-dependent movement of CREB in cortical neuron in vitro: A study using single molecule imaging2016
- Author(s)
  N. Sugo, H. Kitagawa, N. Yamamoto
- Organizer
  ACS2016
- Place of Presentation
  同志社大学・寒梅館（京都）
- Year and Date
  2016-03-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] Efficient disruption of gene function with CRISPR/Cas9 system in cultured primary cortical neurons2016
- Author(s)
  Hiroto Tsunematsu, Noriyuki Sugo, Akiko Uyeda, Nobuhiko Yamamoto
- Organizer
  Circuit Construction in the Mammalian Brain
- Place of Presentation
  大阪府・吹田市
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Activity-dependent dynamics of CREB in cortical neurons: A single-molecule imaging study2015
- Author(s)
  H. KITAGAWA, N. SUGO, N. YAMAMOTO
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] DNA polymerase β activity in neural progenitors is required for postmitotic neuronal survival in the developing cortex2015
- Author(s)
  Onishi, k., Sugo, N., Toyoda, S., Hirayama, T., Yagi, T. & Yamamoto, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] DNA polymerase β activity in neural progenitors is required for postmitotic neuronal survival in the developing cortex2015
- Author(s)
  Onishi, k., Sugo, N., Toyoda, S., Hirayama, T., Yagi, T. & Yamamoto, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] 生後発達過程の大脳皮質においてPolβ欠損神経細胞は2本鎖DNA切断を異常に蓄積させる2015
- Author(s)
  植田尭子、大西公平、菅生紀之、豊田峻輔、平山晃斉、八木健、山本亘彦
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会 (BMB 2015)
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Activity-dependent dynamics of CREB in cortical neurons: A single-molecule imaging study2015
- Author(s)
  Kitagawa, H., Sugo., N. & Yamamoto, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] DNA polymerase β activity in neural progenitors is required for postmitotic neuronal survival in the developing cortex2015
- Author(s)
  K. ONISHI, N. SUGO, S. TOYODA, T. HIRAYAMA, T. YAGI, N. YAMAMOTO
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] Polβ deficiency increases DNA double-strand breaks in postnatal cortical neurons2015
- Author(s)
  Uyeda, A., Onishi, K., Sugo, N., Toyoda S., Hiyayama, T., Yagi, T. & Yamamoto, N.
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04260
[Presentation] Activity-dependent dynamics of CREB in cortical neurons: A single-molecule imaging study2015
- Author(s)
  H. KITAGAWA, N. SUGO, N. YAMAMOTO
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] Polβ deficiency increases DNA double-strand breaks in postnatal cortical2015
- Author(s)
  Uyeda, A., Onishi, K., Sugo, N., Toyoda S., Hiyayama, T., Yagi, T. & Yamamoto, N.
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] Activity-dependent dynamics of CREB in cortical neurons: A single-molecule imaging study2015
- Author(s)
  Kitagawa, H., Sugo., N. & Yamamoto, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] Efficient Disruption of CREB Function Using CRISPR/Cas9 System in Primary Cortical Neuron Cultures2015
- Author(s)
  恒松大翔、植田尭子、菅生紀之、山本亘彦
- Organizer
  遺伝研研究会 2015年「哺乳類脳の機能的神経回路の構築メカニズム」
- Place of Presentation
  国立遺伝学研究所（三島）
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-15K14350
[Presentation] 大脳皮質神経細胞における神経活動依存的な転写調節因子CREB動態の1分子イメージング解析2014
- Author(s)
  北川宏信、菅生紀之、大國紋、山本亘彦
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜　（横浜）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] Transcription factor dynamics revealed by single-molecule imaging in cortical neurons2014
- Author(s)
  菅生紀之
- Organizer
  第57回日本神経化学会大会・第36回日本生物学的精神医学会　合同年会
- Place of Presentation
  奈良県新公会堂　（奈良）
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] Single-Molecule Imaging Reveals Dynamics of CREB Transcription Factor in Living Cells2013
- Author(s)
  Noriyuki Sugo, Masatoshi Morimatsu, Yoshiyuki Arai, Yoshinori Kousoku, Aya Ohkuni, Taishin Nomura, Toshio Yanagida, Nobuhiko Yamamoto
- Organizer
  The 23rdCDB Meeting Building multi cellular systems from Cellular Cross-Talk
- Place of Presentation
  神戸
- Year and Date
  2013-01-22
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] 大脳皮質神経細胞分化における DNA 修復酵素 DNA ポリメラーゼ β の機能に関する研究2013
- Author(s)
  大西公平, 菅生紀之, 山本亘彦
- Organizer
  第6回神経発生討論会
- Place of Presentation
  和光
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] Single-molecule imaging of transcription factor CREB in living cells2012
- Author(s)
  Sugo, Noriyuki
- Organizer
  Society for Neuroscience 42nd annual meeting
- Place of Presentation
  New Orleans, The U.S.A.
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] 1分子イメージングによる転写因子CREBの動態解析2012
- Author(s)
  菅生　紀之
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] １分子イメージングによる転写因子CREBの動態解析2012
- Author(s)
  菅生紀之
- Organizer
  第３５回分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23111516
[Presentation] Single-Molecule Imaging of Transcription Factor CREB in Living Cells2012
- Author(s)
  Noriyuki Sugo, Masatoshi Morimatsu, Yoshiyuki Arai, Yoshinori Kousoku, Aya Ohkuni, Taishin Nomura, Toshio Yanagida, Nobuhiko Yamamoto
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] 1分子イメージングによる転写因子 CREB の動態解析2012
- Author(s)
  菅生紀之, 森松賢順, 新井由之, 香束剛章, 大國紋, 野村泰伸, 柳田敏雄, 山本亘彦
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] Single-molecule imaging of transcription factor CREB in living cells2012
- Author(s)
  Noriyuki Sugo
- Organizer
  Neuroscience2012
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PUBLICLY-23111516
[Presentation] 1分子イメージングによる転写因子 CREBの核内動態解析2012
- Author(s)
  菅生紀之、森松賢順、新井由之、香束剛章、大國紋、野村泰伸、柳田敏雄、山本亘彦
- Organizer
  第35回日本神経科学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] Single-molecule imaging of transcription factor CREB in living cells2012
- Author(s)
  Sugo N, Morimatsu M, Arai Y , Kousoku K, Ohkuni A, Nomura T , Yanagida T , Yamamoto N
- Organizer
  Society for Neuroscience 42nd annual meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] 1分子イメージングによる転写因子 CREB の核内動態解析2012
- Author(s)
  菅生紀之, 森松賢順, 新井由之, 香束剛章, 大國紋, 野村泰伸, 柳田敏雄, 山本亘彦
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] 山本亘彦1分子イメージングによる転写因子 CREB の動態解析2012
- Author(s)
  菅生紀之、森松賢順、新井由之、香束剛章、大國紋、野村泰伸、柳田敏雄
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] 1分子イメージングによる転写因子CREBの核内動態解析2012
- Author(s)
  菅生　紀之
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] 1分子イメージングによる転写因子CREBの核内動態解析2012
- Author(s)
  菅生　紀之
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] １分子イメージングによる転写因子CREBの核内動態解析2012
- Author(s)
  菅生紀之
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23111516
[Presentation] 1分子イメージングによる転写因子CREBの動態解析2012
- Author(s)
  菅生　紀之
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] Single-molecule imaging of transcription factor CREB in living cells, Society for Neuroscience 42nd annual meeting2012
- Author(s)
  Sugo, Noriyuki
- Organizer
  Society for Neuroscience 42nd annual meeting
- Place of Presentation
  New Orleans, The U.S.A.
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PLANNED-23115102
[Presentation] Histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching by shuttling from the nucleus to cytoplasm in an activity-dependent fashion2011
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N.
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] Nucleocytoplasmic translocation of the histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching2011
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N.
- Organizer
  Cortical Development
- Place of Presentation
  CHANIA, GREECE
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PUBLICLY-23111516
[Presentation] Histone deacetylase 9 (HDAC9) reglates thalamocortical axon branching by shuttling from the nucleus to cytoplasm in an activity-dependent fashion2011
- Author(s)
  Alchini R, Sugo N, Yamamoto N
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] Histone deacetylase 9 (HDAC9) regulates thalamocortical axon　branching by shuttling from the nucleus to cytoplasm in an activity-dependent fashion2011
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] Nucleocytoplasmic translocation of the histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching2011
- Author(s)
  Alchini R, Sugo N, Yamamoto N
- Organizer
  Cortical Development Meeting 2011
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-23300118
[Presentation] Nucleocytoplasmic translocation of the histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching2011
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N.
- Organizer
  Cortical Development
- Place of Presentation
  CHANIA, GREECE
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] Histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching by shuttling from the nucleus to cytoplasm in an activity-dependent fashion2011
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PUBLICLY-23111516
[Presentation] DNA repair enzymes form foci in cortical progenitor cells in association with transcription2010
- Author(s)
  Noriyuki Sugo, et al.
- Organizer
  Neuro2010(第33回日本神経科学大会)
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21700404
[Presentation] 発生期大脳皮質の前駆細胞においてDNA修復酵素は転写活性と連動して集積する2010
- Author(s)
  菅生紀之,至田充宏,山本亘彦
- Organizer
  第33回日本神経科学大会,(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20200009
[Presentation] DNA repair enzymes form foci in cortical progenitor cells in association with transcription2010
- Author(s)
  Noriyuki Sugo, et al.
- Organizer
  Neuro2010 (第33回日本神経科学大会)
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20200009
[Presentation] 発生期大脳皮質の前駆細胞においてDNA修復酵素は転写活性と連動して集積する2010
- Author(s)
  菅生紀之, 至田充宏, 山本亘彦
- Organizer
  第33回日本神経科学大会(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21700404
[Presentation] Activity-dependent nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons2009
- Author(s)
  Noriyuki Sugo, et al.
- Organizer
  Construction and Reconstruction of the Brain
- Place of Presentation
  淡路夢舞台(兵庫県)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20200009
[Presentation] Activity-dependent nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth indeveloping cortical neurons2009
- Author(s)
  Noriyuki Sugo, Hiroaki Oshiro, Mitsuhiro Takemura, Toshiaki Kobayashi, Yusuke Kohno, Naofumi Uesaka
- Organizer
  Construction and Reconstruction of the Brain
- Place of Presentation
  Awaji Yumebutai
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21700404
[Presentation] Activity-dependent nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth indeveloping cortical neurons.2009
- Author(s)
  Noriyuki Sugo, Hiroaki Oshiro, Mitsuhiro Takemura, Toshiaki Kobayashi, Yusuke Kohno, Naofumi Uesaka
- Organizer
  Construction and Reconstruction of theBrain
- Place of Presentation
  Awaji Yumebutai
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20200009
[Presentation] Activity-dependent nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons2009
- Author(s)
  Noriyuki Sugo, et al.
- Organizer
  Construction and Reconstruction of the Brain
- Place of Presentation
  淡路夢舞台(兵庫県)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21700404
[Presentation] Activity-dependent nucleocytoplasmic translocation of TORC1 regulates gene expression and dendritic growth in developing cortical neurons.2008
- Author(s)
  Sugo N, Kobayashi T, Yamamoto N
- Organizer
  Axon Guidance, Synaptogenesis & Neural Plasticity.
- Place of Presentation
  Cold Spring Harbor, New York
- Data Source
  KAKENHI-PROJECT-20300110
[Presentation] 大脳皮質神経細胞におけるHDAC9の神経活動依存的な核・細胞質間移動による遺伝子発現と樹状突起形成の制御2007
- Author(s)
  Sugo N, Oshiro H, Song W, Yamamoto N
- Organizer
  第30回日本神経科学・第50回日本神経化学会・第17回日本神経回路学会大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300105
[Presentation] Nucleocytoplasmic translocation of the histone deacetylase 9 (HDAC9) regulates thalamocortical axon branching2001
- Author(s)
  Alchini, R., Sugo, N., Yamamoto, N
- Organizer
  Cortical Development
- Place of Presentation
  Chania, Greece
- Year and Date
  2001-05-20
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] ＤＮＡポリメラーゼβの神経前駆細胞における作用が大脳皮質における神経細胞分化に必要である
- Author(s)
  大西公平、菅生紀之、豊田峻輔、平山晃斉、八木健、山本亘彦
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] Single-molecule imaging of transcription factor CREB in living cells
- Author(s)
  Noriyuki Sugo
- Organizer
  Neuroscience2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] １分子イメージング法を用いた大脳皮質神経細胞における神経活動依存的な転写調節因子CREB動態の解析
- Author(s)
  菅生紀之
- Organizer
  国立遺伝学研究所研究会「哺乳類脳の機能的神経回路の構築メカニズム」
- Place of Presentation
  三島
- Invited
- Data Source
  KAKENHI-PROJECT-25640035
[Presentation] １分子イメージングによる転写因子CREBの動態解析
- Author(s)
  菅生紀之
- Organizer
  第３５回分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23700447
[Presentation] １分子イメージングによる転写因子CREBの核内動態解析
- Author(s)
  菅生紀之
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23700447

1. YAMAMOTO Nobuhiko (00191429)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
2. ARAI Yoshiyuki (20444515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Higuchi Mayumi (30837795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 北田一博 (70263093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤島和人 (20525852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIRAYAMA Teruyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugo Noriyuki 菅生 紀之

SUGO Noriyuki 菅生 紀之

Research Projects

Research Products

Co-Researchers

神経細胞の能動的DNA脱メチル化による大脳形成メカニズムの解明Principal Investigator

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Effect of vitamin C on neural development of the cerebral cortex.

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Mutagenesis in cortical developmentPrincipal Investigator

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Dynamics of neuronal activity-dependent gene expression

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Single Molecule Imaging of Transcription Dynamics in Neuronal DifferentiationPrincipal Investigator

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A study of DNA repair dynamics during neuronal differentiation using single-molecule imagingPrincipal Investigator

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Cytoskeleton mechanisms of activity-dependent axon branching

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A study of neuronal activity-dependent transcription factor dynamics using single-molecule imagingPrincipal Investigator

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脳形成における細胞移動とクロマチン動態のイメージング解析Principal Investigator

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A study of the molecular mechanism underlying activity-dependent thalamocortical axon branching

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Chromatin Dynamics Associated with Neuronal DifferentiationPrincipal Investigator

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Axon branch remodeling mechanisms in mesoscopic neuronal circuit formation

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Chromatin Dynamics during Neuronal DifferentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Sugo Noriyuki 菅生紀之

SUGO Noriyuki 菅生紀之