TAKADA Shuji 高田修治

Researcher Number	20382856
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, システム発生・再生医学研究部, 部長
Affiliation (based on the past Project Information) *help	2015 – 2024: 国立研究開発法人国立成育医療研究センター, システム発生・再生医学研究部, 部長 2016: 国立成育医療研究センター, 研究所, 部長 2015: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2011 – 2014: 独立行政法人国立成育医療研究センター, システム発生・再生医学研究部, 部長 2013: 国立成育医療研究センター, システム発生・再生医学研究部, 部長 … More 2011: 独立行政法人国立成育医療研究センター, 研究所システム発生・再生医学研究部, 部長 2010: Jichi Medical University, ゲノム機能研究室, 室長 2010: 独立行政法人国立成育医療研究センター, システム発生・再生医学研究部, 室長 2009: 国立成育医療センター(研究所), 成育社会医学研究部, 室長 2009: National Research Institute for Child Health and Development, 成育生態学研究室, 室長 2008: Jichi Medical University, 医学部, 助教 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Developmental biology / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 44020:Developmental biology-related / General anatomy (including histology/embryology) / Biological Sciences Except Principal Investigator Human genetics / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 47040:Pharmacology-related … More / Basic Section 45010:Genetics-related / Pediatrics / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56060:Ophthalmology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Endocrinology / Medical genome science / Orthopaedic surgery / Biological Sciences Less
Keywords	Principal Investigator マウス / 性分化 / 性決定 / Sox9 / ゲノム編集 / 生殖腺 / エンハンサー / microRNA / SRY / SOX9 … More / 遺伝子改変マウス / 性スペクトラム / 遺伝子発現調節 / 遺伝子発言調節 / マイクロRNA / 卵巣 / 精巣 / 性差 / フォリキュラー細胞 / セルトリ細胞 / Wholemount in situ hybridization / WISH / 転写因子 / メチル化 / Dlk1 / ゲノムインプリント / mRAP … More Except Principal Investigator ゲノム編集 / 性分化疾患 / 性分化 / インプリンティング / ノックインマウス / 副腎 / モデルマウス / MIRAGE症候群 / ビオチンリガーゼ / トランスポーター / RNF183 / ユビキチン / リソソーム / ユビキチンリガーゼ / iPS細胞 / 遺伝子調節 / 胎盤 / エピジェネティクス / 体細胞 / 性腺 / 分化転換 / 性の多様性 / 体細胞分化転換 / レトロトランスポソン / レトロトランスポゾン / mRNAワクチン / 遺伝子改変マウス / SAMD9 / 高浸透圧 / BioID / NKCC1 / 近位ビオチン標識法 / アポトーシス / イオントランスポーター / ビオチン / 炎症性腸疾患 / 浸透圧 / female細胞 / ヒト受精胚 / 生命発動 / 器官発生 / 多能性幹細胞 / X染色体不活化 / X染色体 / SOX9 / XO / トゲネズミ / ES細胞 / Muller細胞 / 移植 / 創薬 / 低酸素培養 / 軸索 / 視神経移植 / 神経経路探索 / ミュラー細胞 / グリア細胞 / 網膜神経節細胞 / ヒトiPS細胞 / ALDH2*2 / 栄養疫学 / ゲノム編集技術 / 12q24領域 / 多因子疾患予防 / 食嗜好 / オンライン料理画像調査 / フェノムワイド関連解析 / ゲノムワイド関連解析 / ゲノム編集マウス / BMI / 食事画像調査 / プレシジョン栄養 / アルコール脱水素酵素 / 食事調査法 / うまみ嗜好性 / 食行動 / rs671 / ALDH2 / 一塩基多型 / テーラーメイド栄養 / 発生分化 / 副腎低形成 / 副腎低形成症 / 病理所見 / 表現型 / エピゲノム / 腫瘍モデル / ポリコーム / Bcor / BCOR / 小児腫瘍 / ユビキチン化 / mTOR / TFEB / ライソゾーム / ノックイン / アミノ酸トランスポーター / LAPTM / LAT1 / LAPTM4A / 神経分化 / RNF182 / mTORC1 / マイクロRNA / 14q32 / 肝芽腫 / 14番染色体 / miRNA / 網羅的メチル化解析 / 網羅的 / アレイ / メチル化解析 / インプリンティング異常症 / MLID / DNAメチル化 / white adipose tissue / genomic imprinting / Klf14 / 白色脂肪組織 / KLF14 / ゲノムインプリンティング / ips細胞 / 先天性副腎皮質過形成 / 11β水酸化酵素欠損症 / 21水酸化酵素欠損症 / アデノウィルス随伴ウィルスベクター / 遺伝子治療 / 先天性副腎皮質過形成症 / 次世代シークエンサ－ / ゲノム解析 / 性分化疾患（DSD） / アレイCGH / 次世代シークエンス / スプライス異常 / 機能亢進変異 / エクソーム解析 / PROKR2 / GATA4 / 遺伝子変異 / ナンセンス随伴性スプライス変更 / AR / NR5A1 / MAP3K1 / 遺伝子解析 / 発生・分化 / 臨床 / マウス / 疾患 / クロマチン / Gonadal development / Sex determination / Mouse / Polycomb / ラブドミオザルコーマ / 靭帯 / 関節 / Mｋｘ / RP58 / Mkx / 腱 / 筋 / エピ変異 / 生殖補助医療 / 臨床像 / 成長障害 Less

哺乳類の性決定期にSRYがSox9を発現誘導する分子機構の解明Principal Investigator
- Principal Investigator
  
  高田修治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
Elucidation of the mechanism of sexual diversity and pathophysiology of DSDs using a model of somatic cell transdifferentiation
- Principal Investigator
  
  鹿島田健一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Medical and Dental University
核酸ワクチンやゲノム編集遺伝子治療に係る安全性の評価と安全な運用に資する研究
- Principal Investigator
  
  小野竜一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  National Institute of Health Sciences
Identification of physiological substrates of osmotic stress-responsive ubiquitin ligase using genome editing, and its involvement in colitis
- Principal Investigator
  
  KANEKO Masayuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Nagasaki University
Pathogenesis of adrenal insufficiency in MIRAGE syndrome revealed by genetically modified mouse
- Principal Investigator
  
  Hasegawa Tomonobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Keio University
Identification of the regulatory mechanism of human SOX9 expression using micePrincipal Investigator
- Principal Investigator
  
  Takada Shuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  National Center for Child Health and Development
哺乳類常染色体性決定遺伝子Sox9の発現量調節機構の解明Principal Investigator
- Principal Investigator
  
  高田修治
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Center for Child Health and Development
Elucidating the Molecular Mechanisms in Human Fertilized Embryos Governing Developmental Initiation and Organogenesis Regulation
- Principal Investigator
  
  Akutsu Hidenori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  National Center for Child Health and Development
The production and analyses of model mice having new genetic abnormality responsible for adrenal hypoplasia
- Principal Investigator
  
  AMANO Naoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
Molecular basis research for personalized nutrition
- Principal Investigator
  
  Igarashi Maki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
  National Center for Child Health and Development
Regeneration of the retina and optic nerve by use of retinal ganglion cells generated from human iPS cells
- Principal Investigator
  
  Azuma Noriyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Medical and Dental University
  National Center for Child Health and Development
A novel sex-determining mechanism in the mammalian species lacking SRY
- Principal Investigator
  
  Kuroiwa Asato
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Hokkaido University
Elucidation of the function of miRNAs at the 14q32.2 imprinted region in the placental development and hepatoblastoma development
- Principal Investigator
  
  Kagami Masayo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  National Center for Child Health and Development
Regulatory mechanism of mTOC1 signaling by ubiquitin ligase RNF182 involved in neural differentiation
- Principal Investigator
  
  Kaneko Masayuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Nagasaki University
  Hiroshima University
Generation and characterization of BCOR-ITD tumor models
- Principal Investigator
  
  Ueno Hitomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  National Center for Child Health and Development
The pathogenesis of MIRAGE syndrome revealed by model mice using genome editing
- Principal Investigator
  
  Hasegawa Tomonobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Keio University
Identification and functional analysis of a gonadal Sox9 enhancerPrincipal Investigator
- Principal Investigator
  
  TAKADA SHUJI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Center for Child Health and Development
Identification of a new gene for 46,XY disorders of sex development
- Principal Investigator
  
  Hasegawa Yukihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tokyo Metropolitan Children's Medical Center (Department of Clinical Research)
Elucidation of pathogenic mechanisms of disorders of sex development using systematic molecular analysis
- Principal Investigator
  
  Igarashi Maki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center for Child Health and Development
Development of gene therapy for congenital adrenal hyperplasia using AAV vectors and iPS cells
- Principal Investigator
  
  Naiki Yasuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center for Child Health and Development
Mouse polycomb targets in gonadal development
- Principal Investigator
  
  Katoh-Fukui Yuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  National Center for Child Health and Development
Elucidation of the onset mechanism of human imprinting disorders using the method of methylation analysis with high-density DNA methylation arrays
- Principal Investigator
  
  Kagami Masayo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  National Center for Child Health and Development
Functional analysis of microRNA in gonadogenesis and gonadal function.Principal Investigator
- Principal Investigator
  
  TAKADA Shuji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  National Center for Child Health and Development
マウス全転写因子の発現解析をもとにした性差構築の分子機構の解明Principal Investigator
- Principal Investigator
  
  高田修治
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
KLF14 biology: its physiological roles and transcriptional regulation
- Principal Investigator
  
  NAKABAYASHI Kazuhiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Center for Child Health and Development
Dlk1-Dio3インプリント制御領域の機能解析Principal Investigator
- Principal Investigator
  
  高田修治
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
マウス全転写因子の発現解析をもとにした性差構築機構の解明Principal Investigator
- Principal Investigator
  
  高田修治
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
Analysis of Muscle and Tendon Development and its application to Medicine
- Principal Investigator
  
  ASAHARA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical and Dental University
Molecular network and functional analysis of gonad specific microRNAPrincipal Investigator
- Principal Investigator
  
  TAKADA Shuji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Research Institute for Child Health and Development
ヒト生殖系列におけるインプリンティング制御機構の解明
- Principal Investigator
  
  鏡雅代
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
Elucidation of the pathogenic mechanism and the clinical spectrum of disorders associated with imprinted genes on human chromosome 14
- Principal Investigator
  
  KAGAMI Masayo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  National Research Institute for Child Health and Development
Functional analysis of microRNAs on sex determination and differentiationPrincipal Investigator
- Principal Investigator
  
  TAKADA Shuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Jichi Medical University

[Book] ゲノム編集【COLUMN】. 生殖医療遺伝カウンセリングマニュアル改訂2版 (Genetic Counseling for Reproductive Medicine: A Practice Manual)2021
- Author(s)
  高田修治
- Total Pages
  166
- Publisher
  中外医学社
- ISBN
  9784498160200
- Data Source
  KAKENHI-PROJECT-19H03810
[Journal Article] Chromosomal microdeletion leading to pituitary gigantism through hormone-gene overexpression2023
- Author(s)
  Katoh-Fukui Yuko、Hattori Atsushi、Zhang Ruogu、Terao Miho、Takada Shuji、Nakabayashi Kazuhiko、Hata Kenichiro、Yamada Yutaka、Matsuura Nobuo、Fukami Maki
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 32 Issue: 14 Pages: 2318-2325
- DOI
  10.1093/hmg/ddad053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00550
[Journal Article] SOX9 and SRY binding sites on mouse mXYSRa/Enh13 enhancer redundantly regulate <i>Sox9</i> expression to varying degrees2022
- Author(s)
  Ogawa Yuya、Terao Miho、Tsuji-Hosokawa Atsumi、Tsuchiya Iku、Hasegawa Midori、Takada Shuji
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 32 Issue: 1 Pages: 55-64
- DOI
  10.1093/hmg/ddac184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06678, KAKENHI-PROJECT-20K18208
[Journal Article] Human SRY Expression at the Sex-determining Period is Insufficient to Drive Testis Development in Mice2021
- Author(s)
  Tsuji-Hosokawa Atsumi、Ogawa Yuya、Tsuchiya Iku、Terao Miho、Takada Shuji
- Journal Title
  
  Endocrinology
  
  Volume: 163 Issue: 1
- DOI
  10.1210/endocr/bqab217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04935, KAKENHI-PROJECT-20H00550, KAKENHI-PROJECT-20K06678, KAKENHI-PROJECT-20K18208
[Journal Article] SOX9 is colocalized with paraspeckle protein NONO in cultured murine sertoli cells and features structural characteristics of intrinsically disordered proteins2020
- Author(s)
  Akiba Kazuhisa、Narumi Satoshi、Nishimura Riko、Kato‐Fukui Yuko、Takada Shuji、Hasegawa Yukihiro、Fukami Maki
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 87 Issue: 11 Pages: 1124-1125
- DOI
  10.1002/mrd.23425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06428, KAKENHI-PROJECT-20H00550, KAKENHI-PROJECT-19H03627, KAKENHI-PROJECT-18K06926
[Journal Article] Temple Syndrome in a Patient With Variably Methylated CpGs at the Primary MEG3/DLK1:IG-DMR and Severely Hypomethylated CpGs at the Secondary MEG3:TSS-DMR2019
- Author(s)
  Kagami M, Yanagisawa A, Ota M, Matsuoka K, Nakamura A, Matsubara K, Nakabayashi K, Takada S, Fukami M, Ogata T.
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 11 Issue: 1 Pages: 41-41
- DOI
  10.1186/s13148-019-0640-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06356, KAKENHI-PLANNED-17H06428, KAKENHI-PROJECT-17H01588, KAKENHI-PROJECT-17H04204
[Journal Article] Renal medullary tonicity regulates RNF183 expression in the collecting ducts via NFAT52019
- Author(s)
  Maeoka Yujiro、Okamoto Takumi、Wu Yan、Saito Atsushi、Asada Rie、Matsuhisa Koji、Terao Miho、Takada Shuji、Masaki Takao、Imaizumi Kazunori、Kaneko Masayuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 514 Issue: 2 Pages: 436-442
- DOI
  10.1016/j.bbrc.2019.04.168
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06685, KAKENHI-PROJECT-19K16373, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06416
[Journal Article] Mapping of a responsible region for sex reversal upstream of Sox9 by production of mice with serial deletion in a genomic locus.2018
- Author(s)
  Yuya Ogawa, Miho Terao, Satoshi Hara, Moe Tamano, Haruka Okayasu, Tomoko Kato, Shuji Takada.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 17514-17514
- DOI
  10.1038/s41598-018-35746-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07429, KAKENHI-PROJECT-16K21664
[Journal Article] Phenotypic Variation in 46,XX Disorders of Sex Development due to the NR5A1 p.R92W Variant: A Sibling Case Report and Literature Review.2018
- Author(s)
  Takasawa K, Igarashi M, Ono M, Takemoto A, Takada S, Yamataka A, Ogata T, Morio T, Fukami M, Kashimada K.
- Journal Title
  
  Sexual Development
  
  Volume: 24 Issue: 5-6 Pages: 5-6
- DOI
  10.1159/000485868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09979, KAKENHI-PLANNED-17H06428, KAKENHI-PROJECT-17J40246
[Journal Article] Genome editing for the reproduction and remedy of human diseases in mice2018
- Author(s)
  Hara Satoshi、Takada Shuji
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 2 Pages: 107-113
- DOI
  10.1038/s10038-017-0360-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07429
[Journal Article] FGFR1 Analyses in Four Patients with Hypogonadotropic Hypogonadism with Split-Hand/Foot Malformation: Implications for the Promoter Region.2017
- Author(s)
  Ohtaka K, Fujisawa Y, Takada F, Hasegawa Y, Miyoshi T, Hasegawa T, Miyoshi H, Kameda H, Kurokawa-Seo M, Fukami M, Ogata T.
- Journal Title
  
  Hum Mutat.
  
  Volume: 38 Issue: 5 Pages: 503-506
- DOI
  10.1002/humu.23178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09817, KAKENHI-PROJECT-17K10074, KAKENHI-PROJECT-26461524
[Journal Article] Sustained endocrine profiles of a girl with WAGR syndrome2017
- Author(s)
  Takada Yui、Sakai Yasunari、Matsushita Yuki、Ohkubo Kazuhiro、Koga Yuhki、Akamine Satoshi、Torio Michiko、Ishizaki Yoshito、Sanefuji Masafumi、Torisu Hiroyuki、Shaw Chad A.、Kagami Masayo、Hara Toshiro、Ohga Shouichi
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 18 Issue: 1 Pages: 117-117
- DOI
  10.1186/s12881-017-0477-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09991, KAKENHI-PROJECT-15K15096
[Journal Article] Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues.2017
- Author(s)
  Igarashi M, Fukami M et al.
- Journal Title
  
  Hum Mutat.
  
  Volume: 38 Issue: 1 Pages: 39-42
- DOI
  10.1002/humu.23116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293224, KAKENHI-PROJECT-16K08593, KAKENHI-PROJECT-16K08603, KAKENHI-PROJECT-16K09979
[Journal Article] The p.R92W variant of NR5A1/Nr5a1 induces testicular development of 46,XX gonads in humans, but not in mice: phenotypic comparison of human patients and mutation-induced mice2016
- Author(s)
  Miyado M, Inui M, Igarashi M, Katoh-Fukui Y, Takasawa K, Hakoda A, Kanno J, Kashimada K, Miyado K, Tamano M, Ogata T, Takada S, Fukami M
- Journal Title
  
  Biol Sex Differ
  
  Volume: 7 Issue: 1 Pages: 56-56
- DOI
  10.1186/s13293-016-0114-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293363, KAKENHI-PROJECT-26670733, KAKENHI-PROJECT-15K06917, KAKENHI-PROJECT-16K08603, KAKENHI-PROJECT-16K09979
[Journal Article] DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation2015
- Author(s)
  Miyata K, Miyata T, Nakabayashi K, Okamura K, Naito M, Kawai T, Takada S, Kato K, Miyamoto S, Hata K, Asahara H
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: 24 Issue: 2 Pages: 410-423
- DOI
  10.1093/hmg/ddu457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23770273, KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-26560076, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113008, KAKENHI-PROJECT-15H02560
[Journal Article] Lack of Skeletal Dysplasia in Patients with Missense Mutations and Upstream Deletion of SOX9.2015
- Author(s)
  Katoh-Fukui Y, Igarashi M, Nagasaki K, Horikawa R, Nagai T, Tsuchiya T, Suzuki E, Miyado M, Hata K, Nakabayashi K, Hayashi K, Matsubara Y, Baba T, Morohashi K, Igarashi A, Ogata T, Takada S, and Fukami M
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 3 Issue: 6 Pages: 550-557
- DOI
  10.1002/mgg3.165
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06917, KAKENHI-PROJECT-15K19439, KAKENHI-PROJECT-15K19538, KAKENHI-PLANNED-22132002, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-26860837, KAKENHI-PROJECT-26870887, KAKENHI-PROJECT-26293224
[Journal Article] The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates2014
- Author(s)
  Onizuka N, Ito Y, Inagawa M, Nakahara H, Takada S, Lotz M, Toyama Y, Asahara H
- Journal Title
  
  J Orthop Sci
  
  Volume: 19(1) Issue: 1 Pages: 172-80
- DOI
  10.1007/s00776-013-0485-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249071, KAKENHI-PUBLICLY-24115707, KAKENHI-PROJECT-24659669
[Journal Article] Comprehensive and quantitative multilocus methylation analysis reveals the susceptibility of specific imprinted differentially methylated regions (DMRs) to aberrant methylation in Beckwith-Wiedemann syndrome with epimutations2014
- Author(s)
  Maeda T, Higashimoto K, Jozaki K, Hitomi H, Nakabayashi K, Makita Y, Tonoki H, Okamoto N, Takada F, Ohashi H, Migita M, Kosaki R, Matsubara K, Ogata T, Matsuo M, Hamasaki Y, Ohtsuka Y, Nishioka K, Joh K, Mukai T, Hata K, Soejima H
- Journal Title
  
  Genet Med
  
  Volume: 16(12) Issue: 12 Pages: 903-912
- DOI
  10.1038/gim.2014.46
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-25461554, KAKENHI-PROJECT-25461648, KAKENHI-PROJECT-25860898, KAKENHI-PROJECT-26670169
[Journal Article] Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system2014
- Author(s)
  Inui M, Miyado M, Igarashi M, Tamano M, Kubo A, Yamashita S, Asahara H, Fukami M, Takada S.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 5396-5396
- DOI
  10.1038/srep05396
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25132713, KAKENHI-PROJECT-25871177, KAKENHI-PROJECT-26860837, KAKENHI-PROJECT-26870887, KAKENHI-PROJECT-26870891
[Journal Article] Targeted gene deletion of miRNAs in mice by TALEN system.2013
- Author(s)
  Takada S, Sato T, Ito Y, Yamashita S, Kato T, Kawasumi M, Kanai-Azuma M, Igarashi A, Kato T, Tamano M, Amahara H.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 10 Pages: e76004-e76004
- DOI
  10.1371/journal.pone.0076004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00119, KAKENHI-PROJECT-23249071, KAKENHI-PROJECT-23570265, KAKENHI-PUBLICLY-24115707, KAKENHI-PROJECT-24659669, KAKENHI-PUBLICLY-25132713, KAKENHI-PROJECT-25860139
[Journal Article] Production of Sry knockout mouse using TALEN via oocyte injection.2013
- Author(s)
  Kato T, Miyata K, Sonobe M, Yamashita S, Tamano M, Miura K, Kanai Y, Miyamoto S, Sakuma T, Yamamoto T, Inui M, Kikusui T, Asahara H, Takada S.
- Journal Title
  
  Scientific reports
  
  Volume: 3 Issue: 1 Pages: 3136-3136
- DOI
  10.1038/srep03136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570265, KAKENHI-PUBLICLY-24115707, KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-24657156, KAKENHI-PLANNED-25118007, KAKENHI-PUBLICLY-25132713, KAKENHI-PROJECT-25890014
[Journal Article] The AERO System : a 3D-like Approach for Recording Gene Expression Patterns in the Whole Mouse Embryo2013
- Author(s)
  Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H
- Journal Title
  
  PLOS One
  
  Volume: 8(10) Issue: 10 Pages: e75754-e75754
- DOI
  10.1371/journal.pone.0075754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249071, KAKENHI-PUBLICLY-24115707, KAKENHI-PROJECT-24659669
[Journal Article] Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos.2009
- Author(s)
  Takada S, Berezikov E, Choi YL, Yamashita Y, Mano H
- Journal Title
  
  RNA 15
  
  Pages: 1507-1514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570210
[Journal Article] Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos2009
- Author(s)
  Takada S, et al.
- Journal Title
  
  RNA 15
  
  Pages: 1507-1514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] アルコール感受性一塩基多型はヒトおよびマウスのうま味嗜好性に影響する2022
- Author(s)
  五十嵐　麻希、野川　駿、中出恵梨香、近都航太、古川　恭平、煙山紀子、福井由宇子、高田修治、八谷　剛史、高橋　祥子、斉藤　憲司、賈　慧娟、加藤　久典
- Organizer
  第76回　日本栄養食糧学会
- Data Source
  KAKENHI-PROJECT-19K11709
[Presentation] Znrf3エクソン2はマウスX-zoneの分化に重要である：ゲノム編集を用いたin vivo解析2021
- Author(s)
  内田登天野直子高田修治小林杏子村上智亮鳴海覚志石井智弘長谷川奉延
- Organizer
  第54回日本小児内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08260
[Presentation] ゲノムヒト化マウスモデルによるin vivoでのヒトSOX9発現調節候補領域の機能解析.2020
- Author(s)
  辻敦美、小川湧也、寺尾美穂、菊池咲希、土屋育、高田修治
- Organizer
  第43回日本分子生物学会（国内学会）
- Data Source
  KAKENHI-PROJECT-20K06678
[Presentation] SNPsを利用したゲノム編集による疾患候補領域重複マウスの作製.2020
- Author(s)
  小川湧也、原聡史、浜田万里果、岡村晴紀、土屋育、辻敦美、後藤友二、久保田宗一郎、寺尾美穂、高田修治
- Organizer
  第43回日本分子生物学会（招待講演）（国内学会）
- Invited
- Data Source
  KAKENHI-PROJECT-20K06678
[Presentation] トゲネズミ属におけるSRY遺伝子に依存しない性決定の分子メカニズム2019
- Author(s)
  黒岩麻里，奥野未来，伊藤武彦，寺尾美穂，小川湧也，高田修治，水島秀成
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03267
[Presentation] マウスを用いたゲノム編集による性分化疾患責任配列の1塩基レベルマッピング.2019
- Author(s)
  小川湧也、寺尾美穂、原聡史、玉野萌恵、岡安春佳、加藤朋子、高田修治
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07429
[Presentation] Identification of a regulatory sequence of Sox9 expression in gonads at single-nucleotide level.2019
- Author(s)
  Shuji Takada
- Organizer
  Symposium “Molecular Genetics of Mammalian Development”
- Data Source
  KAKENHI-PROJECT-17K07429
[Presentation] ゲノム編集技術によるマウス胎仔期生殖腺におけるSox9の発現をシスに調節する配列の探索.2018
- Author(s)
  高田修治
- Organizer
  第41回日本分子生物学会年会ワークショップ「脊椎動物の性決定、性分化の分子機構」
- Data Source
  KAKENHI-PROJECT-17K07429
[Presentation] NR5A1ミスセンス変異p.R92Wは、ヒトとマウスに共通する46,XY精巣形成不全とヒト特異的46,XX精巣形成を招く2017
- Author(s)
  宮戸真美, 乾雅史, 五十嵐麻希, 福井由宇子, 玉野萌恵, 宮戸健二, 緒方勤, 高田修治, 深見真紀
- Organizer
  第21回日本生殖内分泌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K09979
[Presentation] NR5A1は、46,XX精巣性性分化疾患の新規発症責任遺伝子である.2016
- Author(s)
  五十嵐麻希, 高澤啓, 箱田明子, 菅野潤子, 高田修治, 乾雅史, 宮戸真美, 福井由宇子, 鳴海覚志, 田島敏広, 秦健一郎, 中林一彦, 松原洋一, 緒方勤, 鹿島田健一,深見真紀
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-16K09979
[Presentation] Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues.2016
- Author(s)
  Igarashi M, Takasawa K, Hakoda A, Kanno J, Takada S, Miyado M, Tajima T, Sekido R, Ogata T, Kashimada K, Fukami M
- Organizer
  第50回日本小児内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K09979
[Presentation] Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues.2016
- Author(s)
  Igarashi M, Takasawa K, Hakoda A, Kanno J, Takada S, Miyado M, Tajima T, Sekido R, Ogata T, Kashimada K, Fukami M.
- Organizer
  The 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society,
- Place of Presentation
  東京
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09979
[Presentation] NR5A1は、46,XX精巣性性分化疾患の新規発症責任遺伝子である2016
- Author(s)
  五十嵐麻希, 高澤啓, 箱田明子, 菅野潤子, 高田修治, 乾雅史, 宮戸真美, 福井由宇子, 田島敏広, 秦健一郎, 中林一彦, 松原洋一, 緒方勤, 鹿島田健一,深見真紀
- Organizer
  第39回日本小児遺伝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K09979
[Presentation] SOX9はオス生殖腺においてDhhの発現を直接制御する2013
- Author(s)
  山下聡,加藤朋子,山口勝司,重信秀治,乾雅史,高田修治,浅原弘嗣
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] ハイスループット・スクリーニング系を用いた卵巣形成関連候補因子の制御因子の探索2013
- Author(s)
  乾雅史,加藤朋子,五十嵐ありさ,浅原弘嗣,高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] TALEN技術を用いたSry KOマウスの作出2013
- Author(s)
  加藤朋子,宮田康平,園部未来,山下聡,玉野萌恵,宮本新吾,佐久間哲史,山本卓,乾雅史,菊水健史,浅原弘嗣,高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] 生殖腺特異的マイクロRNAの同定と機能解析 Identification and characterisation of gonad-specific microRNA2012
- Author(s)
  高田修治
- Organizer
  第35回日本分子生物学会年会 :ワークショップ「哺乳類の性分化・性成熟の新知見:性腺機能を制御する遺伝子ネットワークとその破綻による疾患」
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] MicroRNA-202 is specifically expressed in the gonads through early to terminal differentiation stages in the mouse2012
- Author(s)
  Shuji Takada
- Organizer
  Sixth International Symposium on The Biology of Vertebrate Sex Determination
- Place of Presentation
  King Kamehameha's Kona Beach Hotel(Hawaii、USA)
- Year and Date
  2012-04-25
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] 生殖腺特異的マイクロRNAの同定と機能解析2012
- Author(s)
  高田修治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PUBLICLY-23132511
[Presentation] MicroRNA-202 is specifically expressed in the gonads through early to terminal differentiation stages in the mouse2012
- Author(s)
  Shuji Takada
- Organizer
  Sixth International Symposium on The Biology of Vertebrate Sex Determination
- Place of Presentation
  King Kamehameha’s Kona Beach Hotel（Hawaii, USA）
- Year and Date
  2012-04-25
- Data Source
  KAKENHI-PUBLICLY-23132511
[Presentation] microRNA-202は生殖腺特異的に生殖腺分化初期から発現する2011
- Author(s)
  高田修治, 他5名
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] microRNA-202は生殖腺特異的に生殖腺の分化初期から発現する2011
- Author(s)
  高田修治,渡辺義隆,久貝朋子,玉野萌恵,五十嵐ありさ,浅原弘嗣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2010
- Author(s)
  Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe , Osamu Arisaka, Toshiro Nagai, Shuji Takada, Maki Fukami, Kazuki Yamazawa, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata
- Organizer
  International Snmposium on Pediatric Endocrinology
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] ヒト14q32.2のインプリンティング領域においてIG-DMRとMEG3-DMRは異なった役割をはたす2010
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第4回エピジェネティクス研究会
- Place of Presentation
  鳥取
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2010
- Author(s)
  Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe, Osamu Arisaka, Toshiro Nagai, Shuji Takada, Maki Fukami, Kazuki Yamazawa, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] 14番染色体インプリンティング遺伝子の胎盤における機能の解明2010
- Author(s)
  鏡雅代、加藤芙弥子、宮戸真美、高田修治、松岡健太郎、山中美智子、金子さおり、松原圭子、佐藤智子、緒方勤
- Organizer
  第44回日本小児内分泌学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PUBLICLY-21028026
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2010
- Author(s)
  Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe, Osamu Arisaka, Toshiro Nagai, Shuji Takada, Maki Fukami, Kazuki Yamazawa, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata.
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PUBLICLY-21028026
[Presentation] ヒト14q32.2のインプリンティング領域において、IG-DMRとMEG3-DMRは異なった役割をはたす2010
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第4回エピジェネティクス研究会
- Place of Presentation
  鳥取
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PUBLICLY-21028026
[Presentation] 14番染色体インプリンティング遺伝子の胎盤における機能の解明2010
- Author(s)
  鏡雅代、加藤芙弥子、宮戸真美、高田修治、松岡健太郎、山中美智子、金子さおり、松原圭子、佐藤智子、緒方勤
- Organizer
  第44回日本小児内分泌学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] 次世代シークエンサーとマイクロRNA研究.2010
- Author(s)
  高田修治
- Organizer
  第11回運動器科学研究会特別講演最先端の研究技術による生物学シリーズ
- Place of Presentation
  軽井沢
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] 次世代シークェンサーとマイクロRNA研究2010
- Author(s)
  高田修治
- Organizer
  第11回運動器科学研究会
- Place of Presentation
  万平ホテル軽井沢(長野県)
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2010
- Author(s)
  Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe, Osamu Arisaka, Toshiro Nagai, Shuji Takada, Maki Fukami, Kazuki Yamazawa, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata.
- Organizer
  International Snmposium on Pediatric Endocrinology
- Place of Presentation
  Tokyo
- Year and Date
  2010-04-01
- Data Source
  KAKENHI-PUBLICLY-21028026
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2010
- Author(s)
  Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe, Osamu Arisaka, Toshiro Nagai, Shuji Takada, Maki Fukami, Kazuki Yamazawa, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata.
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] ヒト14q32.2のインプリンティング領域において、IG-DMRとMEG3-DMRは異なった役割をはたす2010
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第4回エピジェネティクス研究会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] microRNAの網羅的プロファイリング2009
- Author(s)
  高田修治, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] 14番染色体インプリンティング遺伝子群の調節において, IG-DMRとMEG3-DMRは異なった役割を果たす2009
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] 14番染色体インプリンティング遺伝子群の調節において, IG-DMRとMEG3-DMRは異なった役割をはたす2009
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第3回日本エピジェネティクス研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] Essential role of the MEG3-DMR in the regulation of the maternally inherited human chromosome 14q32.2 imprinting region.2009
- Author(s)
  Masayo Kagami, Maki Fukami, Maureen O'Sullivan, Andrew Green, Shuji Takada, Fumiko Kato, Anne Ferguson-Smith, Tsutomu Ogata
- Organizer
  The 24th Naito Conference
- Place of Presentation
  Sapporom
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] 14番染色体インプリンティング遺伝子群の調節において,IG-DMRとMEG3-DMRは異なった役割をはたす.2009
- Author(s)
  鏡雅代, 高田修司
- Organizer
  第3回日本エピジェネティクス研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PUBLICLY-21028026
[Presentation] 14番染色体インプリンティング遺伝子群の調節において, IG-DMRとMEG3-DMRは異なった役割をはたす2009
- Author(s)
  鏡雅代、高田修治、加藤芙弥子、Anne C Ferguson-Smith、緒方勤
- Organizer
  第43回日本小児内分泌学会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region.2009
- Author(s)
  Masayo Kagami, Shuji Takada, Maki Fukami, Kazuki Yamazaw, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390101
[Presentation] Comprehensive analysis of microRNA expression.2009
- Author(s)
  Shuji Takada, Yoshihiro Yamashita, Hiroshi Asahara, Hiroyuki Mano
- Organizer
  第68回日本癌学会 Symposium on microRNA and cancer
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] 雄のマウス胎児期生殖巣では始原生殖細胞でribosomal RNAからmicroRNAが生合成されている2008
- Author(s)
  高田修治、上野敏秀、間野博行
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] 雄のマウス胎児期生殖巣では始原生殖細胞でribosomal RNAからmicroRNAが生合成されている2008
- Author(s)
  高田修治
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20570210
[Presentation] MicroRNA-202 is specifically expressed in the gonads through early to terminal differentiation stages in the mouse
- Author(s)
  Shuji Takada
- Organizer
  Sixth International Symposium on The Biology of Vertebrate Sex Determination
- Place of Presentation
  King Kamehameha’s Kona Beach Hotel（Hawaii, USA）
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] TALEN技術を用いたSry KOマウスの作出
- Author(s)
  加藤朋子, 宮田康平, 園部未来, 山下聡, 玉野萌恵, 宮本新吾, 佐久間哲史, 山本卓, 乾雅史, 菊水健史, 浅原弘嗣, 高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25132713
[Presentation] TALEN技術を用いたSry KOマウスの作出
- Author(s)
  加藤朋子, 宮田康平, 園部未来, 山下聡, 玉野萌恵, 宮本新吾, 佐久間哲史, 山本卓, 乾雅史, 菊水健史, 浅原弘嗣, 高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] マウス胎児期雌性生殖腺分化に関わる転写因子・転写コファクターの機能解析
- Author(s)
  加藤朋子, 原聡史, 玉野萌恵, 秋元未来, 乾雅史, 浅原弘嗣, 高田修治
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25132713
[Presentation] SOX9はオス生殖腺において Dhhの発現を直接制御する
- Author(s)
  山下聡, 加藤朋子, 山口勝司, 重信秀治, 乾雅史, 高田修治, 浅原弘嗣
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] ハイスループット・スクリーニング系を用いた卵巣形成関連候補因子の制御因子の探索
- Author(s)
  乾雅史, 加藤朋子, 五十嵐ありさ, 浅原弘嗣, 高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25132713
[Presentation] ハイスループット・スクリーニング系を用いた卵巣形成関連候補因子の制御因子の探索
- Author(s)
  乾雅史, 加藤朋子, 五十嵐ありさ, 浅原弘嗣, 高田修治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PROJECT-23570265
[Presentation] SOX9はオス生殖腺において Dhhの発現を直接制御する
- Author(s)
  山下聡, 加藤朋子, 山口勝司, 重信秀治, 乾雅史, 高田修治, 浅原弘嗣
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25132713
[Presentation] 生殖腺特異的マイクロRNAの同定と機能解析(Identification and characterisation of gonad-specific microRNA)
- Author(s)
  高田　修治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23570265

1. KAGAMI Masayo (70399484)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. NAKABAYASHI Kazuhiko (10415557)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. AMANO Naoko (70348689)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 深見真紀 (40265872)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. YAMAZAWA Kazuki (10338113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. Katoh-Fukui Yuko (50342639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. Igarashi Maki (10623035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. Kaneko Masayuki (10322827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Hasegawa Tomonobu (20189533)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 鳴海覚志 (40365317)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 石井智弘 (70265867)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. OGATA Tsutomu (40169173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
13. ASAHARA Hiroshi (70294460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. Hasegawa Yukihiro (70172898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. Naiki Yasuhiro (20470007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOMIKAWA Junko (80534990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAYAMA Chiharu (60774445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Ueno Hitomi (30435630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Azuma Noriyuki (10159395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Kuroiwa Asato (20372261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. Akutsu Hidenori (50347225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 加藤朋子 (10638802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 勝又規行 (10260340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 松原圭子 (90542952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 栗木清典 (20543705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 加藤久典 (40211164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 賈慧娟 (60456324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. 目加田優子 (60617281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 長幡友実 (40512512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 小久保友貴 (10610066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 横井匡 (80514025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 伊藤武彦 (90501106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 福田篤 (00638091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 佐渡敬 (70321601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 小野竜一 (10401358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 鹿島田健一 (80451938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. SUGAHARA Naoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. SANEFUJI Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 岡村浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 宮戸健二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKADA Shuji 高田 修治

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哺乳類の性決定期にSRYがSox9を発現誘導する分子機構の解明Principal Investigator

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Identification of the regulatory mechanism of human SOX9 expression using micePrincipal Investigator

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哺乳類常染色体性決定遺伝子Sox9の発現量調節機構の解明Principal Investigator

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TAKADA Shuji 高田修治