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Ogawa Shuhei  小川 修平

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… Alternative Names

小川 修平  オガワ シユウヘイ

OGAWA Shuhei  小川 修平

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Researcher Number 20385553
Other IDs
Affiliation (Current) 2025: 東京理科大学, 研究推進機構生命医科学研究所, 講師
Affiliation (based on the past Project Information) *help 2022 – 2023: 東京理科大学, 研究推進機構生命医科学研究所, 講師
2011 – 2013: 東京理科大学, 生命医科学研究所, 助教
2009 – 2011: 東京理科大学, 生命科学研究所, 助教
2007: Tokyo University of Science, 生命科学研究所, 助教
2006: 東京理科大学, 生命科学研究所, 助手
Review Section/Research Field
Principal Investigator
Laboratory animal science
Except Principal Investigator
Basic Section 28050:Nano/micro-systems-related / Immunology
Keywords
Principal Investigator
CD28 / 補助シグナル / T細胞 / GVH病 / 病態モデル / GVH病動物モデル / 制御性T細胞 / 全身性強皮症動物モデル / 疾患モデル / PI3キナーゼ … More / Grb2ファミリー分子 / トランスジェニックマウス / ICOS / 免疫学 / 実験動物学 … More
Except Principal Investigator
白血球 / 循環腫瘍細胞 / マイクロ流体デバイス / CTC / マイクロスリット / 吸引穴 / 抗体 / 特異吸着 / 白血球除去 / マイクロ流路 / 寛容 / サイトカイン / アポトーシス / 移植 / シグナル伝達 / 補助シグナル / T細胞 / 免疫学 / 獲得免疫 Less
  • Research Projects

    (4 results)
  • Research Products

    (44 results)
  • Co-Researchers

    (3 People)
  •  Effect of cell surface roughness on WBC capture using antibody

    • Principal Investigator
      早瀬 仁則
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 28050:Nano/micro-systems-related
    • Research Institution
      Tokyo University of Science
  •  The switching mechanisms of the phenotype of murine chronic Graft-versus-Host Disease from SLE type to SSc type.Principal Investigator

    • Principal Investigator
      OGAWA Shuuhei
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo University of Science
  •  The co-stimulatory effect of CD28 and ICOS on T cell response

    • Principal Investigator
      ABE Ryo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tokyo University of Science
  •  GVH病の発症におけるCD28ファミリー分子の機能的役割の解析Principal Investigator

    • Principal Investigator
      小川 修平
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo University of Science

All 2023 2022 2014 2013 2012 2011 2010 2009 2007

All Journal Article Presentation

  • [Journal Article] Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.2014

    • Author(s)
      Higo K, Oda M, Morii H, Takahashi J, Harada Y, Ogawa S, Abe R.
    • Journal Title

      Immunol Invest.

      Volume: 43 Issue: 3 Pages: 278-291

    • DOI

      10.3109/08820139.2013.875039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590098, KAKENHI-PROJECT-24700438
  • [Journal Article] Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K2014

    • Author(s)
      Higo, K., Oda, M., Morii, H., Takahashi, J., Harada, Y., Ogawa, S., and Abe, R.
    • Journal Title

      Immunol Invest.

      Volume: 43 Pages: 278-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Journal Article] CD28 signaling in primary CD4+ T cells: Identification of both tyrosine phosphorylation-dependent and independent pathway2013

    • Author(s)
      Ogawa, S., Ito, N., Watanabe, S., Watanabe, M., Inutake, Y., Sakurai, Y., Harada, Y., Kishimoto H., and Abe, R.
    • Journal Title

      International Immunology

      Volume: 25 Issue: 12 Pages: 671-681

    • DOI

      10.1093/intimm/dxt028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Journal Article] CD28 signaling in primary CD4+ T cells : Identification of both tyrosine phosphorylation-dependent and independent pathway2013

    • Author(s)
      Ogawa, S., Ito, N., Watanabe, S., Watanabe, M., Inutake, Y., Sakurai, Y., Harada, Y., Kishimoto H., and Abe, R.
    • Journal Title

      Int. Immunol.

      Volume: 25 Pages: 671-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Journal Article] The transcription factor AP-1 is involved in ICOS gene expression downstream of TCR/CD28 signaling and cytokine receptor signaling2012

    • Author(s)
      Watanabe M, Nakajima S, Kazunobu O, Ogawa S, Yamashita M, Nakayama T, Murakami Y, Tanabe K, Abe R
    • Journal Title

      Eur J Immunol

      Volume: 42 Issue: 7 Pages: 1850-1862

    • DOI

      10.1002/eji.201141897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590541, KAKENHI-PROJECT-24700438
  • [Journal Article] The transcription factor AP-1 is involved in ICOS gene expression downstream of TCR/CD28 signaling and cytokins receptor signaling2012

    • Author(s)
      Watanabe, M., Nakajima, S., Ohnuki, K., Ogawa, S., Yamashita, M., Nakayama, T., Murakami, Y., Tanabe, K., Abe, R.
    • Journal Title

      Eur.J.Immunol.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Journal Article] AP-1 transcription factor is involved in ICOS gene expression downstream of TCR/CD28 signaling and cytokine receptor signaling2012

    • Author(s)
      Watanabe, M., Nakajima, S, Ohnuki, K., Ogawa S., Yamashita, M., Nakayama, T., Murakami Y., Tanabe, K. and Abe, R.
    • Journal Title

      European Journal Immunology

      Volume: 42(7) Pages: 1850-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Journal Article] CD8^+T細胞の活性化とCD282010

    • Author(s)
      小川修平
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 53(6) Pages: 562-568

    • Data Source
      KAKENHI-PROJECT-21590541
  • [Journal Article] Suppression of Con A-induced hepatitis induction in ICOS-deficient mice2010

    • Author(s)
      渡辺志保, 大貫和信, 原泰志, 石田康生, 五十嵐美徳, 小川修平, 岸本英博, 田邉一成, 安部良
    • Journal Title

      Immunology letters 128

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Journal Article] Suppression of Con A-induced hepatitis induction in ICOS-deficient mice2009

    • Author(s)
      Watanabe S, Ohnuki K, Hara Y, Ishida Y, Ikarashi Y, Ogawa S, Kishimoto H, Tanabe K, Abe R
    • Journal Title

      Immunol Lett

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] 循環腫瘍細胞捕捉のための白血球除去マイクロ流体デバイスの開発 - 抗体修飾壁面への細胞接触促進 -2023

    • Author(s)
      岡村拓哉、高橋理久、小川修平、早瀬仁則
    • Organizer
      2023年度精密工学会秋季大会学術講演会
    • Data Source
      KAKENHI-PROJECT-22K04900
  • [Presentation] Microfluidic Device of White Blood Cell Elimination for Capturing Circulating Tumor Cells2022

    • Author(s)
      Hayase,M., Murata,A., Takahashi,R., Ogawa,S.
    • Organizer
      19th International Conference on Precision Engineering
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K04900
  • [Presentation] Dual effects of ERK on the clonal expansion of antigen specific CD4+ T cells.2014

    • Author(s)
      Ohtsuka, S., Ogawa, S., and Abe, R.
    • Organizer
      The 53rd Midwinter Conference of Immunologists at Asilomar
    • Place of Presentation
      Asilomar
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The condition of host CD4+Cd25+ regulatory T cells determines the phenotype of chronic Graft-versus-Host Disease2013

    • Author(s)
      Akieda, Y., Nakamura, T., Wakamatsu, E., Ogawa, S., Watanabe, S., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe, Chiba
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The behavior of cytokines determines the cGVHD phenotype.2013

    • Author(s)
      Nakamura, T., Akieda, Y., Ogawa, S., Watanabe, S., Wakamatsu, E., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The condition of host CD4+Cd25+ regulatory T cells determines the phenotype of chronic Graft-versus-Host Disease.2013

    • Author(s)
      Akieda, Y., Nakamura, T., Wakamatsu, E., Ogawa, S., Watanabe, S., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Dual effects of the ERK pathway on the clonal expansion of antigen specific CD4+ T cells.2013

    • Author(s)
      Ohtsuka, S., Iida, M., Yoshida, N., Hiruta, T., Hayashi, S., Watanabe, S., Ogawa, S., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The behavior of cytokines determines the cGVHD phenotype2013

    • Author(s)
      Nakamura, T., Akieda, Y., Ogawa, S., Watanabe, S., Wakamatsu, E., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe, Chiba
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Mechanism of the break in donor-specific tolerance induced by mixed hematopoietic chimerism.2013

    • Author(s)
      Shibata, M., Tashiro, Y., Suzuki, T., Ogawa, S., Wakamatsu, E., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Differential requirement for CD28 cytoplasmic motifs in T cell responses2013

    • Author(s)
      Ogawa, S., Yoshida, N., Sano, S., Ohtsuka, S., Nakamura, T., Akieda, Y., Watanabe, S., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe, Chiba
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Antigen specific CD4+ T cell responses caused by T-T interaction.2013

    • Author(s)
      Iida, M., Ohtsuka,S., Ogawa,S., Watanabe, S., Abe,R.
    • Organizer
      第10回DIA日本年会
    • Place of Presentation
      東京TFTファッションタウンビル(有明)
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Dual effects of ERK pathway on the clonal expansion of antigen specific CD4+ T cells.2013

    • Author(s)
      Ohtsuka, S., Ogawa, S., and Abe, R.
    • Organizer
      The 6th International Workshop of Kyoto T cell Conference 2013
    • Place of Presentation
      Shiran-Kaikan, Kyoto University, Kyoto
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] he role of Y216 in the cytoplasmic tail of CD28 in CD28-mediated costimulation.2013

    • Author(s)
      Sano S., Yoshida N., Shigeta M., Ohtsuka S., Ogawa S., Abe R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Differential requirement for CD28 cytoplasmic motifs in T cell responses.2013

    • Author(s)
      Ogawa, S., Yoshida, N., Sano, S., Ohtsuka, S., Nakamura, T., Akieda, Y., Watanabe, S., and Abe, R.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology, 2013
    • Place of Presentation
      Makuhari Messe
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Influence of the cytokine environment on pathological forms of cGVHD.2012

    • Author(s)
      Nakamura T., Akieda Y., Ogawa S., Watanabe S., Wakamatsu E., and Abe R.
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸国際会議場、神戸国際展示場、神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] Tyrosine phosphorylation of CD28 and CD28-mediated costimulation.2012

    • Author(s)
      Ogawa S., Shigeta M., Yoshida N., Ohtsuka S., Sakurai Y., Watanabe S., and Abe, R
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸国際会議場、神戸国際展示場、神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The conditions of host CD4+CD25+ regulatory T cells determine autoimmune-like chronic Graft-versus-Host Disease phenotype.2012

    • Author(s)
      Akieda Y., Nakamura T., Ogawa S., Watanabe S., Wakamatsu E., Higami Y., and Abe R.
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸国際会議場、神戸国際展示場、神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-24700438
  • [Presentation] The functional relationship between CD28 YMNM and PxxP motifs in CD28-mediated costimulation2011

    • Author(s)
      Ogawa S., Sakurai Y., Katayama A., Shigeta M., Yoshida N., Horibe C., Gamoh S., Ohtsuka S., Maruyama H., Iida M., Hiruta T., and Abe R.
    • Organizer
      第40回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] CD28-mediated signaling through tyrosine phosphorylation-dependent and -independent pathways2011

    • Author(s)
      Ogawa, S., Sakurai, Y., Katayama, A, Kishimoto, H., T., Abe, R
    • Organizer
      第21回Kyoto T Cell Conference
    • Place of Presentation
      京都平安ホテル
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The functional relationship between CD28 YMNM and PxxP motifs in CD28-mediated costimulation2011

    • Author(s)
      Ogawa, S., Sakurai, Y., Katayama, A., Shigeta, M., Yoshida, N., Horibe, C., Gamoh S., Ohtsuka, S., Maruyama, H., Iida, M., Hiruta, T., Abe, R
    • Organizer
      第40回日本免疫学会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Different requirements for induction of the CD28-mediated signal transduction pathway in naive vs activated T cells.2010

    • Author(s)
      Ogawa, S., Watanabe, S., Inutake, Y., Sakurai, Y., Katayama, A., Abe, R.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Different requirements for induction of the CD28-mediated signal transduction pathway in naive vs activated T cells2010

    • Author(s)
      Ogawa S., Watanabe S., Inutake Y., Sakurai Y., Katayama A., and Abe R.
    • Organizer
      14^<th> International Congress of Immunology
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Regulation of CD28 tyrosine phosphorylation and functions induced by its interaction with natural ligand.2010

    • Author(s)
      Katayama, A., Sakurai, Y., Ogawa, S., Watanabe, S., Abe, R.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Antigen-specific CD4+ effector T cells : Analysis of factors regulating clonal expansion, cytokine production and high dose suppression2010

    • Author(s)
      Ohnuki, K., Akashi, T., Murasaki, S., Kobayashi, S., Watanabe S., Ogawa, S., Abe, R.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Localization of Bcl10 during T-APC interaction.2010

    • Author(s)
      Miura, S., Ohnuki, K., Watanabe, S., Kobayashi, S., Ogawa, S., Abe, R.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Role of CD28 expressed on host T cells in pathogenesis of chronic GVHD.2010

    • Author(s)
      Akieda, Y., Ogawa, S., Fujimura, K., Oka, T., Watanabe, S., Hara, Y., Kishimoto, H., Abe, R.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Elucidation of the mechanism of CD28 tyrosine phosphorylation and analysis of its phosphorylation-dependent and -in dependent functions2009

    • Author(s)
      桜井雄一, 小川修平, 犬竹優, 片山愛子, 渡辺志保, 岸本英博, 安部良
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The role of the CD28 transmembrane region in IL-2 production2009

    • Author(s)
      徳丸正輝, 小川修平, 鈴木利宙, 原泰志, 原田陽介, 岸本英博, 安部良
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The effect of CD28 mediated costimulation in response of naive and memory T cells2009

    • Author(s)
      Ogawa S., Inutake Y., Sakurai Y., Miura Y., Katayama A., Higo K., Watanabe S., Kishimoto H., Abe R
    • Organizer
      第39回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The tyrosine phosphprylation of CD28 and CD28 mediated costimulation2009

    • Author(s)
      小川修平, 桜井雄一, 渡辺政志, 渡辺志保, 岸本英博, 安部良
    • Organizer
      Kyoto T Cell Conference 2009
    • Place of Presentation
      京都芝蘭会館
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Role of the CD28 signal expressed on host T cell in pathogenesis of chronic GVHD.n2009

    • Author(s)
      藤村建午, 小川修平, 岡貴弘, 龝枝佑紀, 渡辺志保, 原泰志, 岸本英博, 安部良
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The effect of CS28 mediated costimulation in response of naive and memory T cells2009

    • Author(s)
      小川修平, 犬竹優, 桜井雄一, 三浦幸子, 片山愛子, 肥後邦武, 渡辺志保, 岸本英博, 安部良
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] Contribution of TCR- and CD28-mediated signals to NF-kappa B action2009

    • Author(s)
      犬竹優, 竹田圭, 三浦幸子, 桜井雄一, 小川修平, 岸本英博, 安部良
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590541
  • [Presentation] The role of PxxP motifs in the CD28 cytoplasmic domain for T cell responses2007

    • Author(s)
      小川 修平
    • Organizer
      日本免疫学会学術総会
    • Place of Presentation
      グランドプリンスホテル新高輪
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-18700400
  • 1.  ABE Ryo (20159453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 20 results
  • 2.  早瀬 仁則 (70293058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  原田 陽介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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