Hiroshima Michio 廣島通夫

Researcher Number	20392087
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院生命機能研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪大学, 大学院生命機能研究科, 特任准教授(常勤) 2018 – 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 上級研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 28040:Nanobioscience-related Except Principal Investigator Complex systems
Keywords	Principal Investigator 大規模1分子計測 / １分子生体情報学 / 1分子薬剤スクリーニング / 細胞の多様性 / 細胞状態の多様性 / 1分子生体情報学 / １分子イメージング・ナノ計測 / 薬剤スクリーニング / 細胞内シグナル伝達 / 1分子イメージング … More Except Principal Investigator … More プローブ / シンギュラリティ生物学 / イメージング / ゲノム編集 / タンパク質凝集 / プローブ開発 / １分子イメージング / 脳神経疾患 / アルツハイマー病 / 光遺伝学 / タウ / シンギュラリティ Less

細胞内分子の状態分布に基づく細胞応答多様性の理解とメカニズム解明手法の開拓Principal Investigator
- Principal Investigator
  
  廣島通夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
  Institute of Physical and Chemical Research
受容体分子の時空間ダイナミクスの統合的理解による新規薬剤スクリーニングの基盤構築Principal Investigator
- Principal Investigator
  
  廣島通夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Osaka University
  Institute of Physical and Chemical Research
Elucidation of mechanisms linking between molecular behavior and activation as a basis for in-cell single-molecule screeningPrincipal Investigator
- Principal Investigator
  
  Hiroshima Michio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Institute of Physical and Chemical Research
Research on the molecular mechanism of singularity phenomenon in neurological disorders
- Principal Investigator
  
  Bannai Hiroko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Waseda University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book Patent

[Book] イメージングの選び方・使い方100＋, 第4章超解像顕微鏡「PALM/STORM」2018
- Author(s)
  廣島通夫、上田昌宏
- Total Pages
  2
- Publisher
  羊土社
- ISBN
  9784758103756
- Data Source
  KAKENHI-PROJECT-18H01839
[Journal Article] Automated single-molecule imaging for drug discovery2024
- Author(s)
  Hiroshima M., Ueda M
- Journal Title
  
  Proc. of SPIE.
  
  Volume: 12853 Pages: 1285308-1285308
- DOI
  10.1117/12.3009718
- Data Source
  KAKENHI-PROJECT-22K18363, KAKENHI-PROJECT-19H00982, KAKENHI-PROJECT-23K23856
[Journal Article] １分子イメージングの全自動化と大規模解析への応用2023
- Author(s)
  廣島通夫、上田昌宏
- Journal Title
  
  生産と技術
  
  Volume: 75 Pages: 77-81
- Open Access
- Data Source
  KAKENHI-PROJECT-23K23856
[Journal Article] １分子イメージングの全自動化と大規模解析への応用2023
- Author(s)
  廣島通夫、上田昌宏
- Journal Title
  
  生産と技術
  
  Volume: 75 Pages: 77-81
- Open Access
- Data Source
  KAKENHI-PROJECT-22K18363
[Journal Article] Origin of diverse phosphorylation patterns in the ERBB system2022
- Author(s)
  Okada Takashi、Miyagi Hiraku、Sako Yasushi、Hiroshima Michio、Mochizuki Atsushi
- Journal Title
  
  Biophysical Journal
  
  Volume: 121 Issue: 3 Pages: 470-480
- DOI
  10.1016/j.bpj.2021.12.031
- NAID
  120007187502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-19K03663, KAKENHI-PROJECT-22K18363, KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-23K23856
[Journal Article] Heterotrimeric Gq proteins?act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias2022
- Author(s)
  Kawakami Kouki、Yanagawa Masataka、Hiratsuka Suzune、Yoshida Misaki、Ono Yuki、Hiroshima Michio、Ueda Masahiro、Aoki Junken、Sako Yasushi、Inoue Asuka
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 870-870
- DOI
  10.1038/s41467-022-28056-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05414, KAKENHI-ORGANIZER-21H05111, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-19H00982, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-20J20669, KAKENHI-PROJECT-20K05760, KAKENHI-PROJECT-20H03475
[Journal Article] SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells2022
- Author(s)
  Kawase Naoyuki、Sugihara Atsuya、Kajiwara Kentaro、Hiroshima Michio、Akamatsu Kanako、Nada Shigeyuki、Matsumoto Kunio、Ueda Masahiro、Okada Masato
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 3 Pages: 101630-101630
- DOI
  10.1016/j.jbc.2022.101630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03504, KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-19H00982, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-20K06623, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-19K07639
[Journal Article] DNA‐Based Synthetic Growth Factor Surrogates with Fine‐Tuned Agonism**2021
- Author(s)
  Akiyama Momoko、Ueki Ryosuke、Yanagawa Masataka、Abe Mitsuhiro、Hiroshima Michio、Sako Yasushi、Sando Shinsuke
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 60 Issue: 42 Pages: 22745-22752
- DOI
  10.1002/anie.202105314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-18K06677, KAKENHI-PROJECT-20K05760
[Journal Article] In-Cell Single-Molecule Analysis of Molecular State and Reaction Kinetics Coupling2021
- Author(s)
  Hiroshima Michio、Sako Yasushi
- Journal Title
  
  Advanced Imaging and Bio Techniques for Convergence Science
  
  Volume: 1310 Pages: 59-80
- DOI
  10.1007/978-981-33-6064-8_3
- ISBN
  9789813360631, 9789813360648
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-18H01839
[Journal Article] Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responses2021
- Author(s)
  Miyagi Hiraku、Hiroshima Michio、Sako Yasushi
- Journal Title
  
  Biosystems
  
  Volume: 199 Pages: 104293-104293
- DOI
  10.1016/j.biosystems.2020.104293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-18H01839
[Journal Article] Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells2021
- Author(s)
  Kuwashima Yutaro、Yanagawa Masataka、Abe Mitsuhiro、Hiroshima Michio、Ueda Masahiro、Arita Makoto、Sako Yasushi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 8473-8473
- DOI
  10.3390/ijms22168473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-19H00982, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-18K06677, KAKENHI-PROJECT-20K05760
[Journal Article] AIにより実現した細胞内1分子動態の大規模網羅的イメージング2020
- Author(s)
  廣島通夫
- Journal Title
  
  日本化学会情報化学部会誌（CICSJ Bulletin）
  
  Volume: 38 Pages: 12-15
- NAID
  130007960374
- Data Source
  KAKENHI-PLANNED-18H05414
[Journal Article] AIにより実現した細胞内1分子動態の大規模網羅的イメージング2020
- Author(s)
  廣島通夫
- Journal Title
  
  CICSJ Bulletin
  
  Volume: 38 Issue: 1 Pages: 12
- DOI
  10.11546/cicsj.38.12
- NAID
  130007960374
- ISSN
  0913-3747, 1347-2283
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01839
[Journal Article] Large scale single-molecule imaging aided by artificial intelligence2020
- Author(s)
  Hiroshima, M., Yasui, M., and Ueda, M.
- Journal Title
  
  Microscopy
  
  Volume: 69 Issue: 2 Pages: 69-78
- DOI
  10.1093/jmicro/dfz116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00982, KAKENHI-PLANNED-18H05414, KAKENHI-PROJECT-18H01839
[Journal Article] Transient Acceleration of Epidermal Growth Factor Receptor Dynamics Produces Higher-Order Signaling Clusters2018
- Author(s)
  Hiroshima Michio、Pack Chan-gi、Kaizu Kazunari、Takahashi Koichi、Ueda Masahiro、Sako Yasushi
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 430 Issue: 9 Pages: 1386-1401
- DOI
  10.1016/j.jmb.2018.02.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0087, KAKENHI-PUBLICLY-16H00788, KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-17K18353, KAKENHI-PUBLICLY-17H06021, KAKENHI-PROJECT-18H01839, KAKENHI-PLANNED-18H05414
[Journal Article] Automated single-molecule imaging in living cells2018
- Author(s)
  Yasui Masato、Hiroshima Michio、Kozuka Jun、Sako Yasushi、Ueda Masahiro
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-018-05524-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H06021, KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-18H01839, KAKENHI-PROJECT-15KT0087, KAKENHI-PROJECT-16K00413, KAKENHI-PLANNED-18H05414
[Journal Article] Shift in Conformational Equilibrium Induces Constitutive Activity of G-Protein-Coupled Receptor, Rhodopsin.2018
- Author(s)
  Maeda R, Hiroshima M, Yamashita T, Wada A, Sako Y, Shichida Y, Imamoto Y.
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 122 Issue: 18 Pages: 4838-4843
- DOI
  10.1021/acs.jpcb.8b02819
- NAID
  120006708207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02515, KAKENHI-PROJECT-18H01839, KAKENHI-PROJECT-15KT0087, KAKENHI-PROJECT-16K07319, KAKENHI-PROJECT-16K07437, KAKENHI-PLANNED-18H05414
[Journal Article] Single-molecule diffusion-based estimation of ligand effects on G protein?coupled receptors2018
- Author(s)
  Yanagawa Masataka、Hiroshima Michio、Togashi Yuichi、Abe Mitsuhiro、Yamashita Takahiro、Shichida Yoshinori、Murata Masayuki、Ueda Masahiro、Sako Yasushi
- Journal Title
  
  Science Signaling
  
  Volume: 11 Issue: 548 Pages: 1-16
- DOI
  10.1126/scisignal.aao1917
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06677, KAKENHI-PUBLICLY-17H05870, KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-18H01839, KAKENHI-PROJECT-15KT0087, KAKENHI-PROJECT-15K07957, KAKENHI-PROJECT-16K07437, KAKENHI-PROJECT-16K18533, KAKENHI-PLANNED-18H05414
[Patent] 受容体型チロシンキナーゼの活性評価方法2024
- Inventor(s)
  渡邉大介、廣島通夫、上田昌宏
- Industrial Property Rights Holder
  渡邉大介、廣島通夫、上田昌宏
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-23K23856
[Patent] 受容体型チロシンキナーゼの活性評価方法2024
- Inventor(s)
  渡邉大介、廣島通夫、上田昌宏
- Industrial Property Rights Holder
  渡邉大介、廣島通夫、上田昌宏
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-22K18363
[Patent] 1分子イメージングを用いた上皮成長因子受容体EGFRの活性評価に基づく薬剤スクリーニング法2023
- Inventor(s)
  上田昌宏、廣島通夫、渡邉大介
- Industrial Property Rights Holder
  上田昌宏、廣島通夫、渡邉大介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-031358
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K18363
[Patent] 1分子イメージングを用いた上皮成長因子受容体EGFRの活性評価に基づく薬剤スクリーニング法2023
- Inventor(s)
  上田昌宏、廣島通夫、渡邉大介
- Industrial Property Rights Holder
  上田昌宏、廣島通夫、渡邉大介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-031358
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K23856
[Patent] Method for evaluating activity of g protein-coupled receptor (gpcr)2018
- Inventor(s)
  柳川正隆、佐甲靖志、廣島通夫、安井真人、上田昌宏、冨樫祐一
- Industrial Property Rights Holder
  柳川正隆、佐甲靖志、廣島通夫、安井真人、上田昌宏、冨樫祐一
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H01839
[Patent] オートフォーカス装置ならびにそれを備える光学装置および顕微鏡2018
- Inventor(s)
  安井真人、廣島通夫、上田昌宏
- Industrial Property Rights Holder
  安井真人、廣島通夫、上田昌宏
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-024408
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] Automated single-molecule imaging for drug discovery2024
- Author(s)
  Hiroshima M., Ueda M.
- Organizer
  SPIE. Photonics West（
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18363
[Presentation] Automated single-molecule imaging for drug discovery2024
- Author(s)
  Hiroshima M., Ueda M.
- Organizer
  SPIE. Photonics West
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23856
[Presentation] シグナル伝達を惹起する細胞膜上EGFR動態の1分子解析2023
- Author(s)
  廣島通夫、上田昌宏
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23856
[Presentation] Mechanism of mutation induced changes in single-molecule behavior of EGF receptor2023
- Author(s)
  Hiroshima M.
- Organizer
  Single Molecule Biophysics Conference SMB2023
- Data Source
  KAKENHI-PROJECT-22K18363
[Presentation] シグナル伝達を惹起する細胞膜上EGFR動態の1分子解析2023
- Author(s)
  廣島通夫、上田昌宏
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K18363
[Presentation] Mechanism of mutation induced changes in single-molecule behavior of EGF receptor2023
- Author(s)
  Hiroshima M.
- Organizer
  Single Molecule Biophysics Conference SMB2023
- Data Source
  KAKENHI-PROJECT-23K23856
[Presentation] 遺伝子変異が引き起こすEGFR動態変化の1分子解析2022
- Author(s)
  廣島通夫、上田昌宏
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23856
[Presentation] 遺伝子変異が引き起こすEGFR動態変化の1分子解析2022
- Author(s)
  廣島通夫、上田昌宏
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K18363
[Presentation] 1分子イメージングを用いた薬剤スクリーニング2022
- Author(s)
  渡邉大介、廣島通夫、上田昌宏
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23856
[Presentation] アルツハイマー病モデル細胞における1分子イメージング; ― 全自動1分子イメージングによる大規模画像データ取得に向けて ―2022
- Author(s)
  坂内博子・廣島通夫
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] 1分子イメージングを用いた薬剤スクリーニング2022
- Author(s)
  渡邉大介、廣島通夫、上田昌宏
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K18363
[Presentation] 全自動１分子解析による毒性タウ分子の伝播メカニズムの解明に向けて2021
- Author(s)
  廣島通夫
- Organizer
  新学術領域「シンギュラリティ生物学」第４回領域会議
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] Pharmacological Application of Automated Single-molecule Analysis for EGFR Cancerous Mutants2020
- Author(s)
  廣島通夫、渡邉大輔、上田昌宏
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] 細胞内 1 分子イメージングの自動化と細胞内シグナル伝達への適用2020
- Author(s)
  廣島通夫
- Organizer
  CBI学会2020年大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] 細胞内 1 分子イメージングの自動化と細胞内シグナル伝達への適用2020
- Author(s)
  廣島通夫, 上田昌宏
- Organizer
  CBI学会2020大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] Pharmacological Application of Automated Single-molecule Analysis for EGFR Cancerous Mutants2020
- Author(s)
  廣島通夫, 渡邉大介, 上田昌宏.
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] Regulation of Downstream Signaling by Clusters of Epidermal Growth Factor Receptor2019
- Author(s)
  Michio Hiroshima
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] Regulation of Downstream Signaling by Clusters of Epidermal Growth Factor Receptor2019
- Author(s)
  Hiroshima Michio, Tomishige Nario, Ueda Masahiro, Kobayashi Toshihide, Sako Yasushi
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] 全自動化1分子イメージングによる大規模計測2019
- Author(s)
  廣島通夫
- Organizer
  CBI学会2019年大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] 1分子イメージングで読み解くアルツハイマー病のシンギュラリティ」2019
- Author(s)
  坂内博子、廣島通夫
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] 全自動イメージングにより実現した網羅的1分子解析2019
- Author(s)
  廣島通夫
- Organizer
  第44回レーザ顕微鏡研究会＆シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] 全自動イメージングにより実現した網羅的1分子解析2019
- Author(s)
  廣島通夫、上田昌宏
- Organizer
  第44回レーザ顕微鏡研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] 全自動化 1 分子イメージングによる大規模計測2019
- Author(s)
  廣島通夫
- Organizer
  CBI学会2019年大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] What singularity biology can do for understanding Alzheimer’s disease2019
- Author(s)
  Hiroko Bannai, Michio Hiroshima, Yoshiyuki Soeda, Akihiko Takashima
- Organizer
  第57回生物物理学会年会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414
[Presentation] In Cell Automated Single-molecule Analysis and Its Extensive Applications2018
- Author(s)
  廣島通夫
- Organizer
  第56回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01839
[Presentation] In Cell Automated Single-molecule Analysis and Its Extensive Applications2018
- Author(s)
  廣島通夫
- Organizer
  第56回日本生物物理学会年会，シンポジウム「1分子計測に立脚した新しいバイオ分析の潮流」
- Invited
- Data Source
  KAKENHI-PLANNED-18H05414

1. Bannai Hiroko (40332340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 高島明彦 (00154774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 松本弦 (50415303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松田恵子 (40383765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ABE Mitsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 佐甲靖志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 今元泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山下高廣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 七田芳則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 上田昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hiroshima Michio 廣島 通夫

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細胞内分子の状態分布に基づく細胞応答多様性の理解とメカニズム解明手法の開拓Principal Investigator

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受容体分子の時空間ダイナミクスの統合的理解による新規薬剤スクリーニングの基盤構築Principal Investigator

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Elucidation of mechanisms linking between molecular behavior and activation as a basis for in-cell single-molecule screeningPrincipal Investigator

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Research on the molecular mechanism of singularity phenomenon in neurological disorders

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[Book] イメージングの選び方・使い方100＋, 第4章 超解像顕微鏡 「PALM/STORM」2018

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[Journal Article] Automated single-molecule imaging for drug discovery2024

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[Journal Article] １分子イメージングの全自動化と大規模解析への応用2023

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[Journal Article] １分子イメージングの全自動化と大規模解析への応用2023

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[Journal Article] Origin of diverse phosphorylation patterns in the ERBB system2022

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[Journal Article] Heterotrimeric Gq proteins?act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias2022

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[Journal Article] SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells2022

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[Journal Article] DNA‐Based Synthetic Growth Factor Surrogates with Fine‐Tuned Agonism**2021

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[Journal Article] In-Cell Single-Molecule Analysis of Molecular State and Reaction Kinetics Coupling2021

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[Journal Article] Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responses2021

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[Journal Article] Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells2021

Hiroshima Michio 廣島通夫

[Book] イメージングの選び方・使い方100＋, 第4章超解像顕微鏡「PALM/STORM」2018