IWAMA Hisakazu 岩間久和

… Alternative Names

岩間久和イワマヒサカズ

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Researcher Number	20398035
Other IDs
Affiliation (Current)	2025: 香川大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 香川大学, 医学部, 准教授 2019 – 2023: 香川大学, 医学部, 准教授 2007 – 2018: 香川大学, 総合生命科学研究センター, 准教授 2017: 香川大学, 総合生命科学研究センター遺伝子研究部門, 准教授 2011: 香川大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Evolutionary biology / Basic Section 45020:Evolutionary biology-related / Evolutionary biology Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 52010:General internal medicine-related / Tumor diagnostics / Evolutionary biology
Keywords	Principal Investigator 遺伝子制御網 / マイクロRNA / ターゲット遺伝子 / 協調的遺伝子制御 / 哺乳類 / PAR-CLIP / HITS-CLIP / ゲノムアライメント / 遺伝子の生成死滅過程 / 行列 … More / 協調的制御 / 遺伝子進化 / cis-element / 転写因子 / マイクロＲＮＡ / ゲノム / シミュレーション / マイクロRNAプレカーサー / フィードフォーワード / UTR / フィードフォワード回路 / 冗長性 / オルソログ / ターゲット配列 / 遺伝子族 … More Except Principal Investigator microRNA / 肝細胞癌 / マイクロRNA / ガレクチン-9 / micro RNA / 転移性肝癌 / 耐性株 / 分子標的治療薬 / 抗がん作用 / 耐性癌細胞 / エピガロカテキンガレート / 分子動態 / 早期発見 / 早期胃癌 / 重症化予測 / 非アルコール性脂肪性肝疾患 / 体組成計測 / 非アルコール性脂肪肝炎 / Galectin-9 / Galectin-9 microRNA / 胆管細胞癌 / エクソソーム / 生活習慣病 / ARB / 降圧薬 / 新規化学予防薬 / テルミサルタン / 化学予防薬 / 抗腫瘍薬 / 間葉系腫瘍 / 大腸癌 / バイオマーカー / exosome / 消化管間葉系腫瘍 / 消化管粘膜下腫瘍 / Ｇａｌ-9 / Ｇａｌ－９ / Gal-9 / マイクロＲＮＡ / マイクロ RNA / ドーパミン / ニワトリ / DRD4 / DRD3 / DRD2 / ドーパミン受容体 / 家畜化 / 人為淘汰 / 分子系統樹 / 肝硬変 Less

マイクロRNAの霊長類における新生死滅過程Principal Investigator
- Principal Investigator
  
  岩間久和
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  Kagawa University
Investigation of relevant microRNAs and molecular mechanism for detecting early gastric carcinoma
- Principal Investigator
  
  小原英幹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma
- Principal Investigator
  
  正木勉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Development of a method to predict the severity of nonalcoholic fatty liver disease by measuring body composition and microRNA
- Principal Investigator
  
  Yoneyama Hirohito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Antitumor effects of lifestyle drugs on colorectal cancer: Involvement of antihypertensive drug ARB as a novel chemopreventive agent
- Principal Investigator
  
  Kobara Hideki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Elucidation of pathway and prognostic factor prediction derived from microRNA analysis in gastrointestinal submucosal tumor
- Principal Investigator
  
  Kobara Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kagawa University
Integration process of microRNAs into gene regulatory network and its evolution.Principal Investigator
- Principal Investigator
  
  Iwama Hisakazu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Kagawa University
Evolution of coordinated regulation of microRNAs and transcription factorsPrincipal Investigator
- Principal Investigator
  
  IWAMA Hisakazu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Kagawa University
MicroRNAs as target molecular in metastatic liver cancer
- Principal Investigator
  
  MASAKI Tsutomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Evolutionary Origin and Genetic Differentiation of Dopamine Receptor D2, D3 and D4 Genes of Japanese Domesticated Chickens
- Principal Investigator
  
  KOMIYAMA Tomoyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Tokai University
Molecular evolution of microRNA gene familiesPrincipal Investigator
- Principal Investigator
  
  IWAMA Hisakazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Kagawa University
Comprehensive analysis of microRNA and functional study of cancer-specific microRNA
- Principal Investigator
  
  MASAKI Tsutomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University

[Book] MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools.2013
- Author(s)
  Iwama H. 他（分担執筆）
- Total Pages
  358
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct‐acting antiviral therapies2021
- Author(s)
  Yoneyama H, Morishita A, Iwama H, Fujita K, Takahiro Masaki, Tani J, Tadokoro T, Nomura T, Sakamoto T, Oura K, Takuma K, Nakahara M, Mimura S, Deguchi A, Oryu M, Tsutsui K, Himoto T, Shimotohno K, Wakita T, Kobara H, Masaki T
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 36 Issue: 4 Pages: 1126-1135
- DOI
  10.1111/jgh.15224
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-20K11531, KAKENHI-PROJECT-18K15786
[Journal Article] Association between microRNA-527 and glypican-3 in hepatocellular carcinoma2021
- Author(s)
  Nomura K, Kitanaka A, Iwama H, Tani J, Nomura T, Nakahara M, Ohura K, Tadokoro T, Fujita K, Mimura S, Yoneyama H, Kobara H, Morishita A, Okano K, Suzuki Y, Tsutsi K, Himoto T, Masaki T
- Journal Title
  
  Oncology Letters
  
  Volume: 21 Issue: 3 Pages: 229-229
- DOI
  10.3892/ol.2021.12490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20K11531
[Journal Article] Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma2020
- Author(s)
  Kohno Tomoki、Morishita Asahiro、Iwama Hisakazu、Fujita Koji、Tani Joji、Takuma Kei、Nakahara Mai、Oura Kyoko、Tadokoro Tomoko、Nomura Takako、Yoneyama Hirohito、Kato Kiyohito、Okano Keiichi、Suzuki Yasuyuki、Nishiyama Akira、Himoto Takashi、Masaki Tsutomu
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Issue: 2 Pages: 1727-1733
- DOI
  10.3892/ol.2020.11696
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11531
[Journal Article] Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo.2019
- Author(s)
  Matsui T, Chiyo T, Kobara H, Fujihara S, Fujita K, Namima D, Nakahara M, Kobayashi N, Nishiyama N, Yachida T, Morishita A, Iwama H, Masaki T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 13 Pages: 13-13
- DOI
  10.3390/ijms20133197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11023
[Journal Article] Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model.2019
- Author(s)
  Chiyo T, Fujita K, Iwama H, Fujihara S, Tadokoro T, Ohura K, Matsui T, Goda Y, Kobayashi N, Nishiyama N, Yachida T, Morishita A, Kobara H, Mori H, Niki T, Hirashima M, Himoto T, Masaki T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 11 Pages: 11-11
- DOI
  10.3390/ijms20112634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11023, KAKENHI-PROJECT-19K16747
[Journal Article] Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution.2018
- Author(s)
  Iwama H, Kato K, Imachi H, Murao K, Masaki T.
- Journal Title
  
  PLoS One
  
  Volume: 13(5)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution2018
- Author(s)
  Iwama Hisakazu、Kato Kiyohito、Imachi Hitomi、Murao Koji、Masaki Tsutomu
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 5 Pages: 198142-198142
- DOI
  10.1371/journal.pone.0198142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440197, KAKENHI-PROJECT-18K08518
[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018
- Author(s)
  Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, Nomura T, Tani J, Yoneyama H, Morishita A, Oryu M, Himoto T, Nishitsuji H, Shimotohno K, Omata M, Masaki T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 ameliorates fulminant liver injury.2017
- Author(s)
  Tadokoro T, Morishita A, Sakamoto T, Fujihara S, Fujita K, Mimura S, Oura K, Nomura T, Tani J, Yoneyama H, Iwama H, Himoto T, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Mol Med Rep
  
  Volume: 16(1) Issue: 1 Pages: 36-42
- DOI
  10.3892/mmr.2017.6606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Therapeutic potential of the antidiabetic drug metformin in small bowel adenocarcinoma.2017
- Author(s)
  Chiyo T, Kato K, Iwama H, Fujihara S, Fujita K, Tadokoro T, Ohura K, Samukawa E, Yamana Y, Kobayashi N, Matsunaga T, Nishiyama N, Ayaki M, Yachida T, Morishita A, Kobara H, Mori H, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 50(6) Issue: 6 Pages: 2145-2153
- DOI
  10.3892/ijo.2017.3971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] icroRNA profile of hepatic epithelioid hemangioendothelioma: A case report.2017
- Author(s)
  Morishita A, Iwama H, Yoneyama H, Sakamoto T, Fujita K, Nomura T, Tani J, Miyoshi H, Fujihara S, Nishiyama N, Kobara H, Mori H, Yamamoto N, Okano K, Suzuki Y, Ibuki E, Haba R, Himoto T, Masaki T.
- Journal Title
  
  Oncol Lett
  
  Volume: 13(3) Issue: 3 Pages: 1655-1659
- DOI
  10.3892/ol.2017.5643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Comparison of submucosal tunneling biopsy versus EUS-guided FNA for gastric subepithelial lesions: a prospective study with crossover design2017
- Author(s)
  Kobara Hideki、Mori Hirohito、Nishimoto Naoki、Fujihara Shintaro、Nishiyama Noriko、Ayaki Maki、Yachida Tatsuo、Matsunaga Tae、Chiyo Taiga、Kobayashi Nobuya、Fujita Koji、Kato Kiyohito、Kamada Hideki、Oryu Makoto、Tsutsui Kunihiko、Iwama Hisakazu、Haba Reiji、Masaki Tsutomu
- Journal Title
  
  Endoscopy International Open
  
  Volume: 05 Issue: 08 Pages: E695-E705
- DOI
  10.1055/s-0043-112497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06855
[Journal Article] Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells.2017
- Author(s)
  Akashi E, Fujihara S, Morishita A, Tadokoro T, Chiyo T, Fujikawa K, Kobara H, Mori H, Iwama H, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 38(1) Issue: 1 Pages: 506-514
- DOI
  10.3892/or.2017.5689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma.2016
- Author(s)
  Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 48 Issue: 3 Pages: 1165-1174
- DOI
  10.3892/ijo.2016.3347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.2016
- Author(s)
  Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 35 Issue: 2 Pages: 851-860
- DOI
  10.3892/or.2015.4452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] ヒト・マイクロRNA遺伝子ファミリーの進化と起源推定2014
- Author(s)
  岩間久和
- Journal Title
  
  生体の科学
  
  Volume: 65(1) Pages: 80-90
- NAID
  40019980710
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development2013
- Author(s)
  Iwama H, Murao K, Imachi H, Ishida T
- Journal Title
  
  BMC Genomics
  
  Volume: Vol.11(12) Pages: 228-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] Human microRNAs originated from two periods at accelerated rates in mammalian evolution2013
- Author(s)
  Iwama H, Kato K, Imachi H, Murao K, Masaki T
- Journal Title
  
  Mol Biol Evol
  
  Volume: 30(3) Issue: 3 Pages: 613-26
- DOI
  10.1093/molbev/mss262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590738, KAKENHI-PROJECT-23570273, KAKENHI-PROJECT-24591352
[Journal Article] Human microRNAs originated from two periods at accelerated rates in mammalian evolution2013
- Author(s)
  Iwama H, Kato K, Imachi H, Murao K, Masaki T
- Journal Title
  
  Molecular Biology and Evolution
  
  Volume: Vol.30(1) Pages: 613-626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] Coordinated networks of microRNAs and transcription factors with evolutionary perspectives2013
- Author(s)
  Iwama H
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: Vol.774 Pages: 169-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] Antitumor effect of metformin in esophageal cancer: In vitro study2013
- Author(s)
  Kobayashi M, Kato K, Iwama H, Fujihara S, Nishiyama N, Mimura S, Toyota Y, Nomura T, Nomura K, Tani J, Miyoshi Hi, Kobara H, Mori H, Murao K, Masaki T
- Journal Title
  
  Int J Oncol
  
  Volume: 42(2) Issue: 2 Pages: 517-24
- DOI
  10.3892/ijo.2012.1722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590738, KAKENHI-PROJECT-23570273
[Journal Article] Coordinated Networks of microRNAs and Transcription Factors with Evolutionary Perspectives.2013
- Author(s)
  Iwama H.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 774 Pages: 169-187
- DOI
  10.1007/978-94-007-5590-1_10
- ISBN
  9789400755895, 9789400755901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570273
[Journal Article] The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo2012
- Author(s)
  Kato K, Gong J, Iwama H, Kitanaka A, Tani J, Miyoshi H, Nomura K, Mimura S, Kobayashi M, Aritomo Y, Kobara H, Mori H, Himoto T, Okano K, Suzuki Y, Murao K, Masaki T
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(3) Issue: 3 Pages: 549-60
- DOI
  10.1158/1535-7163.mct-11-0594
- Data Source
  KAKENHI-PROJECT-22590738
[Journal Article] Prediction of protein-destabilizing polymorphisms by manual curation with protein structure.2012
- Author(s)
  Gough CA, Homma K, Yamaguchi-Kabata Y, Shimada MK, Chakraborty R, Fujii Y, Iwama H, Minoshima S, Sakamoto S, Sato Y, Suzuki Y, Tada-Umezaki M, Nishikawa K, Imanishi T, Gojobori T.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 11 Pages: e50445-e50445
- DOI
  10.1371/journal.pone.0050445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570273, KAKENHI-PROJECT-23592562
[Journal Article] MicroRNA Networks Alter to Conform to Transcription Factor Networks Adding Redundancy and Reducing the Repertoire of Target Genes for Coordinated Regulation.2011
- Author(s)
  Hisakazu Iwama
- Journal Title
  
  Molecular Biology and Evolution
  
  Volume: Vol 28 Pages: 639-648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570222
[Journal Article] Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development.2011
- Author(s)
  Iwama H, Murao K, Imachi H, Ishida T
- Journal Title
  
  BMC Genomics. 12(1)
  
  Pages: 228-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570222
[Journal Article] MicroRNA networks alter to conform to transcription factor networks adding redundancy and reducing the repertoire of target genes for coordinated regulation.2011
- Author(s)
  Iwama H, Murao K, Imachi H, Ishida T
- Journal Title
  
  Molecular Biology and Evolution. Vol28(1)
  
  Pages: 639-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570222
[Journal Article] Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development2011
- Author(s)
  Hisakazu Iwama
- Journal Title
  
  BMC Genomics
  
  Volume: (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570222
[Journal Article] Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma2008
- Author(s)
  Mohammad HS, Kurokohchi K, Iwama H, Masaki T, and 21 others (last author)
- Journal Title
  
  Int J Oncol 33(6) 33
  
  Pages: 1157-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590770
[Journal Article] Abundance of microRNA target motifs in the 3'-UTRs of 20 527 human genes2007
- Author(s)
  Iwama H, Masaki T, Kuriyama S
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1805-1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590770
[Journal Article] Abundance of microRNA target motifs in 3^'-UTRs of20527human genes2007
- Author(s)
  Iwama H, Masaki T, Kuriyama S
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1805-1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590770
[Journal Article] Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells : Involvement in the early stages of hepatocarcinogenesis2007
- Author(s)
  Nonomura T, Masaki T, Iwama H, Kurokohchi K,and 8 others (2^<nd>)
- Journal Title
  
  Int J Oncol 30
  
  Pages: 105-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590770
[Patent] ReAlignerVR(プログラム)2010
- Inventor(s)
  Hisakazu Iwama
- Industrial Property Rights Holder
  Hisakazu Iwama
- Acquisition Date
  2010-06-20
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] DAA治療によるウイルス排除後にも肝炎が持続あるいは再燃するC型肝炎患者の血清マイクロRNAの解析2020
- Author(s)
  米山弘人、岩間和久、森下朝洋、谷丈二、野村貴子、藤田浩二、田所智子、大浦杏子、三村志麻、中原麻衣、琢磨慧、坂本鉄平、出口章広、樋本尚志、正木勉
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K11531
[Presentation] 炎症性腸疾患の診断、鑑別における血清microRNA のバイオマーカーとしての同定2018
- Author(s)
  谷内田達夫、藤森絢子、小林伸也、千代大翔、西山典子、小原英幹、森　宏仁、岩間久和、舛形　尚、正木　勉
- Organizer
  第110回日本消化器病学会四国支部例会・第121回日本消化器内視鏡学会四国支部例会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] ヒト・マイクロRNAとターゲットの発現強度の相関とマイクロRNAの古さ2016
- Author(s)
  岩間久和、藤田浩二、井町仁美、村尾孝児、正木勉
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  静岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26440197
[Presentation] マイクロRNAの生起時期と臓器別発現量2015
- Author(s)
  岩間久和、藤田浩二、井町仁美、村尾孝児、正木勉
- Organizer
  日本進化学会第17回大会
- Place of Presentation
  東京
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PROJECT-26440197
[Presentation] ヒト・マイクロRNAの臓器別発現量とターゲット選択特性2015
- Author(s)
  岩間久和、藤田浩二、井町仁美、村尾孝児、正木勉
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  宮城
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26440197
[Presentation] ヒト・マイクロRNAの生起時期と発現量およびターゲット機能2014
- Author(s)
  岩間久和、藤田浩二、井町仁美、村尾孝児、正木勉
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  滋賀
- Year and Date
  2014-09-17
- Data Source
  KAKENHI-PROJECT-26440197
[Presentation] ヒト・マイクロRNAの生起時期と発現量及びターゲット機能2014
- Author(s)
  岩間久和、藤田浩二、井町仁美、村尾孝児、正木勉
- Organizer
  日本進化学会第１6回大会
- Place of Presentation
  大阪
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-26440197
[Presentation] 哺乳類進化過程でのヒト・マイクロRNA生起とターゲット配列との関連2013
- Author(s)
  岩間久和，加藤清仁，井町仁美，村尾孝児，正木勉
- Organizer
  日本進化学会第１5回大会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNAの哺乳類進化における生起数とターゲット配列の相互関連2013
- Author(s)
  岩間久和、加藤清仁、井町仁美、村尾孝児、正木勉
- Organizer
  日本進化学会第15回大会
- Place of Presentation
  茨城
- Year and Date
  2013-08-30
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] 哺乳類進化過程でのヒト・マイクロRNA生起とターゲット配列との関連2013
- Author(s)
  岩間久和、加藤清仁、井町仁美、村尾孝児、正木勉
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  東京
- Year and Date
  2013-09-20
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNAの哺乳類進化における生起数とターゲット配列の相互関連2013
- Author(s)
  岩間久和，加藤清仁，井町仁美，村尾孝児，正木勉
- Organizer
  本遺伝学会第85回大会
- Place of Presentation
  茨城
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNA遺伝子セットにおける起源時期推定と形成の速度2012
- Author(s)
  岩間久和，加藤清仁，井町仁美，村尾孝児，正木勉
- Organizer
  日本遺伝学会第８４回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNA遺伝子セットにおける起源時期推定と形成の速度2012
- Author(s)
  岩間久和、加藤清仁、井町仁美、村尾孝児、正木勉
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNA遺伝子の比較ゲノムによる生起時期の推定2012
- Author(s)
  岩間久和、加藤清仁、井町仁美、村尾孝児、正木勉
- Organizer
  日本進化学会第14回大会
- Place of Presentation
  東京
- Year and Date
  2012-08-23
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] ヒト・マイクロRNA遺伝子の比較ゲノムによる生起時期の推定2012
- Author(s)
  岩間久和，加藤清仁，井町仁美，村尾孝児，正木勉
- Organizer
  日本進化学会第１４回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] MicroRNA Networks Alter to Conform to Transcription Factor Networks Adding Redundancy and Reducing the Target Gene Repertoire for Coordinated Regulation.2011
- Author(s)
  Hisakazu Iwama
- Organizer
  Annual conference of the Society for Molecular Biology and Evolution 2011. Syposium Evolutionary Systems Biology.(招待講演)
- Place of Presentation
  Kyoto, Japan.
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] Evolutionary Study of Japanese Domesticated Chickens through Dopamine Receptor2011
- Author(s)
  T. Komiyama, H. Iwama, Y. Tateno, H. Kobayashi, T. Gojobori
- Organizer
  SMBE2011京都
- Place of Presentation
  京都大学(京都市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] 二重自己抑制性のフィードフォワード遺伝子制御の多細胞性への関与とマイクロRNA寄与の可能性.2011
- Author(s)
  岩間久和
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  京都府
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] 日本鶏を用いたドーパミン受容体D2, D3, D4の遺伝的分化に関する解析2011
- Author(s)
  小見山智義、岩間久和、舘野義男、小林広幸、五條堀孝
- Organizer
  日本進化学会第13回大会
- Place of Presentation
  京都大学(京都市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] 二重自己抑制性のフィードフォワード遺伝子制御の多細胞性への関与とマイクロRNA寄与の可能性2011
- Author(s)
  岩間久和、井町仁美、村尾孝児
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  福岡
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] MicroRNA Networks Alter to Conform to Transcription Factor Networks Adding Redundancy and Reducing the Target Gene Repertoire for Coordinated Regulation2011
- Author(s)
  H. Iwama, H. Imachi, K. Murao
- Organizer
  Annual conference of the Society for Molecular Biology and Evolution
- Place of Presentation
  京都
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-23570273
[Presentation] マイクロRNA遺伝子族による遺伝子制御網の変化の特性2010
- Author(s)
  岩間久和, 他
- Organizer
  日本遺伝学会第82回大会(口演、査読有)
- Place of Presentation
  北海道
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNA遺伝子族による遺伝子制御網構成の特質2010
- Author(s)
  岩間久和
- Organizer
  日本進化学会・第12回大会
- Place of Presentation
  東京工業大学・大岡山キャンパス(東京)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] The Evolutional Relationship between the Domestication of Fighting Roosters and the repeat variation of Dopamine receptor D42010
- Author(s)
  Tomoyoshi. Komiyama, H.Iwama, Y.Nakamura, K.Sato, H.Kobayashi, Y.Tateno, K.Ikeo, H.Inoko, T.Gojobori
- Organizer
  Molecular Biology and Evolution (SMBE)
- Place of Presentation
  Lyon France
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプターDRD4遺伝子の多型と進化にみる闘争心の起源2010
- Author(s)
  小見山智義、岩間久和、中村洋路、佐藤恭子、池尾一穂、小林広幸、猪子英俊、五條堀孝
- Organizer
  日本遺伝学会第82回札幌大会
- Place of Presentation
  北海道大学(北海道)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] マイクロRNA遺伝子族による遺伝子制御網構成の特質2010
- Author(s)
  岩間久和, 他
- Organizer
  日本進化学会第12回大会(口演、査読有)
- Place of Presentation
  東京
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] The Evolutional Relationship between the Domestication of Fighting Roosters and the repeat variation of Dopamine receptor D42010
- Author(s)
  T. Komiyama, H. Iwama, Y. Nakamura, K. Sato, H. Kobayashi, Y. Tateno, H. Inoko, K. Ikeo, T. Gojobori
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution(SMBE 2010) Lyon France
- Place of Presentation
  Lyon Convention Center
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプターDRD4遺伝子の多型と進化にみる闘争心の起源2010
- Author(s)
  小見山智義, 岩間久和, 中村洋路, 佐藤恭子, 池尾一穂, 小林広幸, 猪子英俊, 五條堀孝
- Organizer
  日本遺伝学会第82回札幌大会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] マイクロRNA遺伝子族による遺伝子制御網の変化の特性2010
- Author(s)
  岩間久和
- Organizer
  日本遺伝学会・第82回大会
- Place of Presentation
  北海道大学・高等昨日開発総合センター(北海道)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNA及び転写因子により構成される自己制御組み込み型フィードフォワード回路のヒトゲノムにおけるin silico解析2009
- Author(s)
  岩間久和, 他
- Organizer
  日本人類遺伝学会第54回大会(口演、査読有)
- Place of Presentation
  東京
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNAと転写因子の遺伝子制御ネットワークにおける役割の差異に関する比較ゲノム解析2009
- Author(s)
  岩間久和, 他
- Organizer
  第81回日本遺伝学会大会(口演、査読有)
- Place of Presentation
  長野
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNAと転写因子の遺伝子制御ネットワークにおける役割の差異に関する比較ゲノム解析2009
- Author(s)
  岩間久和
- Organizer
  第81回日本遺伝学会大会
- Place of Presentation
  松本・信州大学理学部
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] ドーパミンレセプター遺伝子の多型と闘鶏用シャモにおけるドメスティーケーション成立過程との関係2009
- Author(s)
  小見山智義, 岩間久和, 中村洋路, 池尾一穂, 小林広幸, 猪子英俊, 五條堀孝
- Organizer
  日本進化学会第11回札幌大会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] マイクロRNA及び転写因子により構成される自己制御組み込み型フィードフォワード回路のヒトゲノムにおける in silico 解析2009
- Author(s)
  岩間久和
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  東京・グランドプリンスホテル高輪
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNAと転写因子による協調的制御のヒトゲノムにおける網羅的in silico解析2008
- Author(s)
  岩間久和, 他
- Organizer
  日本人類遺伝学会第53回大会(口演、査読有)
- Place of Presentation
  神奈川
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] マイクロRNAと転写因子による協調的制御のヒトゲノムにおける網羅的 in silico 解析2008
- Author(s)
  岩間久和
- Organizer
  日本人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-20570222
[Presentation] ワークショップ13「消化器疾患の分子遺伝学的病態」肝癌にて特異的に現弱するmicroRNA-527 の機能解析2008
- Author(s)
  谷丈二、岩間久和、正木勉
- Organizer
  第50回日本消化器病学会大会
- Place of Presentation
  東京
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19590770

1. MASAKI Tsutomu (30335848)

# of Collaborated Projects: 9 results

# of Collaborated Products: 20 results
2. Kobara Hideki (10612476)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
3. 藤田浩二 (50749421)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
4. YONEYAMA Hirohito (80294750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
5. 森下朝洋 (60423430)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
6. 森宏仁 (20568844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
7. ISHIMARU Ichiro (70325322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KUROKOCHI Kazutaka (10294753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 大森典子 (50613410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 谷丈二 (00596075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. 野村貴子 (70645415)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. 千代大翔 (50769346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. 仁木敏朗 (40558508)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. 田所智子 (50813177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 大浦杏子 (80834639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. KOMIYAMA Tomoyoshi (60439685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
17. KOBAYASHI Hiroyuki (60195807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. YOSHIKAWA Masanobu (90276791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. GOJOBORI Takashi (50162136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. NAKAMURA Youji (90463182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
21. TANAKA Tuyoshi (70414919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HIMOTO Takashi (20325343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. DEGUCHI Akihiro (30380174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SUZUKI Yasuyuki (40304092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 藤原新太郎 (30612486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 坂本鉄平 (30769328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 中原麻衣 (00865610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 北中明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWAMA Hisakazu 岩間 久和

岩間 久和 イワマ ヒサカズ

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Co-Researchers

マイクロRNAの霊長類における新生死滅過程Principal Investigator

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Integration process of microRNAs into gene regulatory network and its evolution.Principal Investigator

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Evolution of coordinated regulation of microRNAs and transcription factorsPrincipal Investigator

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Molecular evolution of microRNA gene familiesPrincipal Investigator

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[Book] MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools.2013

IWAMA Hisakazu 岩間久和

岩間久和イワマヒサカズ