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Takahara Masakazu  高原 正和

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TAKAHARA Masakazu  高原 正和

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Researcher Number 20398093
Affiliation (Current) 2025: 九州大学, 大学病院, 特別教員
Affiliation (based on the past Project Information) *help 2009 – 2012: 九州大学, 大学病院, 講師
Review Section/Research Field
Principal Investigator
Dermatology
Except Principal Investigator
Dermatology
Keywords
Principal Investigator
AhR / アゾール / 表皮細胞 / 芳香族炭化水素受容体 / 抗真菌薬 / 活性酸素 / 再生学 / 皮膚炎症
Except Principal Investigator
カテプシンK / サイトカイン … More / サイトケラチン / アルギナーゼ / SATB1 / 線維芽細胞 / EMT / Snail / CD10 / 皮膚悪性腫瘍 Less
  • Research Projects

    (2 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (1 People)
  •  Research for anti-inflammatory and redox effects of antifungal drug in the skinPrincipal Investigator

    • Principal Investigator
      TAKAHARA Masakazu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Kyushu University
  •  Elucidation of the mechanism for development and infiltration of cutaneous squamous cell carcinoma

    • Principal Investigator
      FURUE Masutaka
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kyushu University

All 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] ビデンス・ピローサエキスによるヒト表皮細胞のNrf-2およびNqo1産生亢進2013

    • Author(s)
      高原正和、北和代、永江航之介、八谷顕子、日高らん、磯谷智世、土井和子、竹井賢二郎、古江増隆
    • Journal Title

      西日本皮膚科

      Volume: 75(3)

    • NAID

      40019744983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Journal Article] Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect2012

    • Author(s)
      Gaku Tsuji, Masakazu Takahara, Hiroshi Uchi, Tetsuo Matsuda, Takahito Chiba, Satoshi Takeuchi, Fumiko Yasukawa, Yoichi Moroi, Masutaka Furue
    • Journal Title

      J Invest Dermatol

      Volume: 132(1) Pages: 59-68

    • Data Source
      KAKENHI-PROJECT-23791277
  • [Journal Article] Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect.2012

    • Author(s)
      Gaku Tsuji, Masakazu Takahara, Hiroshi Uchi, Tetsuo Matsuda, Takahito Chiba, Satoshi Takeuchi, Fumiko Yasukawa, Yoichi Moroi, Masutaka Furue.
    • Journal Title

      J Invest Dermatol

      Volume: 132 Pages: 59-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Journal Article] CD10 expressed by fibroblasts and melanoma cells degrades endothelin-1 secreted by human keratinocytes2011

    • Author(s)
      Xie L, Moroi Y, Takahara M, Tsuji G, Oba J, Hayashida S, Takeuchi S, Shan B, Uchi H, Furue M
    • Journal Title

      Eur J Dermatol

      Volume: 21(4) Pages: 505-9

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] CD10-bearing fibroblasts may inhibit skin inflammation by down-modulating substance P2011

    • Author(s)
      Lining Xie, Masakazu Takahara, Takeshi Nakahara, Junna Oba, Hiroshi Uchi, Satoshi Takeuchi, Yoichi Moroi, Masutaka Furue
    • Journal Title

      CD10-bearing fibroblasts may inhibit skin inflammation by down-modulating substance P

      Volume: 303(1) Pages: 49-55

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Stromal expression of cathepsin K in squamous cell carcinoma.2011

    • Author(s)
      Yan X, Takahara M, Furue M, et al
    • Journal Title

      J Eur Acad Dermatol Venereol.

      Volume: 25(3) Pages: 362-365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Cathepsin K-upregulation in fibroblasts promotes matrigel invasive ability of squamous cell carcinoma cells via tumor-derived IL-1α2011

    • Author(s)
      Xie L, Moroi Y, Hayashida S, Tsuji G, Takeuchi S, Shan B, Nakahara T, Uchi H, Takahara M, Furue M
    • Journal Title

      J Dermatol Sci

      Volume: 61(1) Pages: 45-50

    • NAID

      10030889729

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Junna Oba, Takeshi Nakahara, Sayaka Hayashida, Makiko Kido, Lining Xie, Masakazu Takahara, Hiroshi Uchi, Shogo Miyazaki, Takeru Abe, Akihito Hagihara, Yoichi Moroi, Masutaka Furue2011

    • Author(s)
      Junna Oba, Takeshi Nakahara, Sayaka Hayashida, Makiko Kido, Lining Xie, Masakazu Takahara, Hiroshi Uchi, Shogo Miyazaki, Takeru Abe, Akihito Hagihara, Yoichi Moroi, Masutaka Furue
    • Journal Title

      J Am Acad Dermatol

      Volume: 65(6) Pages: 1152-60

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Stromal expression of cathepsin K in squamous cell carcinoma2011

    • Author(s)
      Xiaofeng Yan, Masakazu Takahara, Lining Xie, Yoshinao Oda, Takeshi Nakahara, Hiroshi Uchi, Satoshi Takeuchi, Yating Tu, Yoichi Moroi, Masutaka Furue
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 25(3) Pages: 362-5

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Expression of cathepsin K in neurofibromatosis 1-associated cutaneous malignant peripheral nerve sheath tumors and neurofibromas.2010

    • Author(s)
      Yan X, Takahara M, Furue M, et al
    • Journal Title

      J Dermatol Sci

      Volume: 58 Pages: 227-229

    • NAID

      10027401304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] CD10-bearing fibroblast inhibits matrigel invasive potency of interleukin-1α-producing squamous cell carcinoma by diminishing substance P levels in the tumor microenvironment2010

    • Author(s)
      Xie L, Moroi Y, Tsuji G, Liu M, Hayashida S, Takahara M, Fukagawa S, Takeuchi S, Shan B, Nakahara T, Uchi H, Yokomizo T, Furue M
    • Journal Title

      Cancer Sc

      Volume: 101(12) Pages: 2570-8

    • NAID

      10027834506

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Abundant expression of neuronatin in normal eccrine, apocrine and sebaceous glands and their neoplasms.2010

    • Author(s)
      Dugu L, Takahara M, Furue M, et al
    • Journal Title

      J Dermatol.

      Volume: 37 Pages: 846-848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Expression of cathepsin K in neurofibromatosis 1-associated cutaneous malignant peripheral nerve sheath tumors and neurofibromas2010

    • Author(s)
      Xiaofeng Yan, Masakazu Takahara, Long Dugu, Lining Xie, Chisato Gondo, Makoto Endo, Yoshinao Oda, Takeshi Nakahara, Hiroshi Uchi, Satoshi Takeuchi, Yating Tu, Yoichi Moroi, Masutaka Furue
    • Journal Title

      J Dermatol Sci

      Volume: 58(3) Pages: 227-9

    • NAID

      10027401304

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Cathepsin K expression : a useful marker for the differential diagnosis of dermatofibroma and dermatofibrosarcomaprotuberans2010

    • Author(s)
      Xiaofeng Yan, Masakazu Takahara, Lining Xie, Yating Tu, Masutaka Furue
    • Journal Title

      Histopathology

      Volume: 57(3) Pages: 486-8

    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Cathepsin K expression : a useful marker for the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans.2010

    • Author(s)
      Yan X, Takahara M, Furue M, et al
    • Journal Title

      Histopathology

      Volume: 57 Pages: 486-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] Stromal CD10 expression, as well as increased dermal macrophages a decreased Langerhans cells, are associated with malignant transformation of keratinocytes2009

    • Author(s)
      Takahara M, Furue M, et al
    • Journal Title

      J Cutan Pathol 36(6)

      Pages: 668-674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Journal Article] ビデンス・ピローサエキスによるヒト表皮細胞のNrf-2およびNqo1産生亢進 西日本皮膚科採用

    • Author(s)
      高原正和、北和代、永江航之介、八谷顕子、日高らん、磯谷智世、土井和子、竹井賢二郎、古江増隆
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] an extract from artichoke, inhibits UVB-induced oxidative stress in cultured human keratinocytes2012

    • Author(s)
      Tsuji G, Takahara M, Yan X, Hachiya A, Uchi H, Takeuchi S, Yasukawa F, K. Takei K, Moroi Y, Furue M Cynaropicrin
    • Organizer
      Society of Investigative Dermatology 72nd Annual meeting
    • Place of Presentation
      Raleigh, USA
    • Year and Date
      2012-05-10
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] Immunomodulation by tobacco smoking: A possible mechanism exacerbating skin diseases2012

    • Author(s)
      Masakazu Takahara, Gaku Tsuji, Masutaka Furue
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] Cynaropicrin, an extract from artichoke, inhibits UVB-induced oxidative stress in cultured human keratinocytes.2012

    • Author(s)
      辻学、高原正和ほか
    • Organizer
      Society of Investigative Dermatology 72nd Annual meeting
    • Place of Presentation
      Raleigh, USA
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] Aryl hydrocarbon receptor modulates keratinocyte differentiation by SIRT1 expression2011

    • Author(s)
      Tsuji G, Takahara M, Uchi H, Takeuchi S, Yasukawa F, Moroi Y, Furue M
    • Organizer
      SID 71st Annual Meeting
    • Place of Presentation
      Phoenix, USA
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] Ketoconazole activates nuclear factor-erythroid 2-related factor-2 (Nrf2) via aryl hydrocarbon receptor signaling pathway: A possible mechanism of anti-inflammatory effect2011

    • Author(s)
      Tsuji G, Takahara M, Matsuda T, Uchi H, Takeuchi S, Mitoma C, Moroi Y, Furue M.
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] Cathepsin K expression in skin tumors2011

    • Author(s)
      Masakazu Takahara
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] Immunomodulation by tobacco smoking: A possible mechanism exacerbating skin diseases2011

    • Author(s)
      Takahara M, Tsuji G, Furue M.
    • Organizer
      22nd World Congress of Dermatology(招待講演)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] 22nd World Congress of Dermatology2011

    • Author(s)
      Cathepsin K expression in skin tumors. Masakazu TAKAHARA, Xiaofeng YAN, Yoichi MOROI, Masutaka FURUE
    • Organizer
      Seoul
    • Place of Presentation
      Korea
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] Ketoconazole activates nuclear factor-erythroid 2-related factor-2 (Nrf2) via aryl hydrocarbon receptor signaling pathway: A possible mechanism of anti-inflammatory effect.2011

    • Author(s)
      Tsuji G, Takahara M, Matsuda T, Uchi H, Takeuchi S, Mitoma C, Moroi Y, Furue M.
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23791277
  • [Presentation] 悪性末梢神経鞘腫瘍と神経線維腫におけるカテプシンK発現の検討2010

    • Author(s)
      師井洋一, Xiaofeng Yan,高原正和,古江増隆
    • Organizer
      H22神経皮膚症候群に関する調査研究班会議
    • Place of Presentation
      東京
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] Cathepsin K expression : a useful marker for the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans.2010

    • Author(s)
      高原正和, ほか
    • Organizer
      The first eastern Asian dermatology congress
    • Place of Presentation
      福岡市
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] 古江増隆NF-1に生じた悪性末梢神経鞘腫瘍と神経線維腫におけるカテプシンK発現の検討2010

    • Author(s)
      Xiaofeng Yan、高原正和、Long Dugu、Lining Xie、小田義直、師井洋一
    • Organizer
      第2回日本レックリングハウゼン病学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] Cathepsin K expression : a useful marker for the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans2010

    • Author(s)
      Masakazu Takahara, Xiaofeng Yan, Lining Xie, Yating Tu, Masutaka Furue
    • Organizer
      Cathepsin K expression : a useful marker for the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans
    • Place of Presentation
      福岡市
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591437
  • [Presentation] NF-1に生じた悪性末梢神経鞘腫瘍と神経線維腫におけるカテプシンK発現の検討2010

    • Author(s)
      高原正和, ほか
    • Organizer
      第2回日本レックリングハウゼン病学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-21591437
  • 1.  FURUE Masutaka (70134583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 16 results

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