NAGAFUKU Masakazu 永福正和

Researcher Number	20399976
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2014: 東北薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Functional biochemistry Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator スフィンゴ脂質 / T細胞受容体 / ラフト / 胸腺細胞 / T細胞 / 糖鎖 / 胸腺 / TCR / T細胞分化 / ガングリオシド … More Except Principal Investigator … More 喘息 / アレルギー / T細胞 / KKAyマウス / 過食 / 視床下部 / 慢性炎症 / インスリン抵抗性 / 内臓脂肪 / マクロファージ / メタボリックシンドローム / スフィンゴ糖脂質 / 喘息治療 / アレルギー治療 / CD8+ T細胞 / CD4+ T細胞 / ラフト / 免疫シナプス / ガングリオシド / スフィンゴ等脂質 Less

Role of membrane gangliosides in T cell development and activationPrincipal Investigator
- Principal Investigator
  
  NAGAFUKU Masakazu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku Pharmaceutical University
Emerging pathophysiological roles of ganglioside GM3
- Principal Investigator
  
  INOKUCHI Jin-ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku Pharmaceutical University

All 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] Glycoscience: Biology and Medicine (Gangliosides in T cell immunity)2014
- Author(s)
  Nagafuku, M., Inokuchi, J.
- Total Pages
  7
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25840040
[Book] Sugar Chains (Gangliosides and T cell immunity)2014
- Author(s)
  Nagafuku, M., Inokuchi, J.
- Total Pages
  20
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25840040
[Journal Article] Control of Homeostatic and Pathogenic Balance in Adipose Tissue by Ganglioside GM32015
- Author(s)
  Nagafuku, M., Sato, T., Sato, S., Shimizu, K., Taira, T., Inokuchi, J.
- Journal Title
  
  Glycobiology
  
  Volume: 25 Issue: 3 Pages: 303-318
- DOI
  10.1093/glycob/cwu112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25840040, KAKENHI-PUBLICLY-26110717
[Journal Article] Distinct selectivity of gangliosides required for CD4+ T and CD8+ T cell activation2015
- Author(s)
  Inokuchi, J., Nagafuku, M., Ohno, I., Suzuki, A.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1851 Issue: 1 Pages: 98-106
- DOI
  10.1016/j.bbalip.2014.07.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25840040, KAKENHI-PROJECT-25461164, KAKENHI-PUBLICLY-26110717
[Journal Article] The Physiological Significance of Ganglioside Species Selectively Expressed on Individual T Cell Subsets2013
- Author(s)
  永福　正和，井ノ口　仁一
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 25 Issue: 144 Pages: 159-169
- DOI
  10.4052/tigg.25.159
- NAID
  130004841373
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370064, KAKENHI-PROJECT-25840040
[Journal Article] Heterogeneity of gangliosides among T cell subsets2013
- Author(s)
  Jin-ichi Inokuchi
- Journal Title
  
  Cell Mol Life Sci
  
  Volume: 70 Issue: 17 Pages: 2000-2008
- DOI
  10.1007/s00018-012-1208-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590843, KAKENHI-PROJECT-23370064, KAKENHI-PROJECT-25461164, KAKENHI-PROJECT-25840040
[Journal Article] Heterogeneity of gangliosides among T cell subsets2013
- Author(s)
  Inokuchi J, Nagafuku M, Ohno I. and Suzuki A.
- Journal Title
  
  Cell. Mol. Life Sci
  
  Volume: 70 Pages: 3067-75
- Data Source
  KAKENHI-PROJECT-23370064
[Journal Article] CD4+T細胞とCD8+T細胞の活性化におけるラフトガングリオシドの相違2012
- Author(s)
  Masakazu Nagafuku
- Journal Title
  
  東北薬科大学研究誌
  
  Volume: 59 Pages: 35-43
- NAID
  40018833141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370064
[Journal Article] CD4 and CD8 T cells require different membrane gangliosides for activation2012
- Author(s)
  Nagafuku M, Okuyama K., Onimaru Y., Suzuki A., Odagiri Y., Yamashita T., Iwasaki K., Fujiwara M., Takayanagi M., Ohno I. and Inokuchi J
- Journal Title
  
  Proc. Natl. Acad. Sci.USA
  
  Volume: 109
- Data Source
  KAKENHI-PROJECT-23370064
[Journal Article] CD4 and CD8 T cells require different membrane gangliosides for activation2012
- Author(s)
  Nagafuku M, Okuyama K, Onimaru Y, Suzuki A, Odagiri Y, Yamashita T, Iwasaki K, Fujiwara M, Takayanagi M, Ohno I, Inokuchi J
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 109 Issue: 6
- DOI
  10.1073/pnas.1114965109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590843, KAKENHI-PROJECT-23370064
[Patent] ヘルパーT細胞の選択的機能制御法
- Inventor(s)
  井ノ口仁一, 永福正和, 大野勳, 奥山香織
- Industrial Property Rights Holder
  JST
- Industrial Property Rights Type
  特許
- Overseas
- Data Source
  KAKENHI-PROJECT-23370064
[Patent] 高脂血症治療剤のスクリーニング方法
- Inventor(s)
  井ノ口仁一, 永福正和,㏿水博孝
- Industrial Property Rights Holder
  JST
- Industrial Property Rights Type
  特許
- Overseas
- Data Source
  KAKENHI-PROJECT-23370064
[Presentation] マクロファージによる内臓脂肪細胞のガングリオシド発現の病態生理学的意義2013
- Author(s)
  井ノ口仁一、永福正和
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] Distinct expression profiles of sphingolipid species diring T cell development2013
- Author(s)
  永福正和、井ノ口仁一
- Organizer
  第42回日本免疫学会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] T細胞分化におけるスフィンゴ脂質の発現制御2013
- Author(s)
  永福正和、井ノ口仁一
- Organizer
  第8回スフィンゴテラピー研究会
- Place of Presentation
  石川県加賀市
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] マクロファージは内臓脂肪細胞のガングリオシド発現を時間的・空間的に支配することにより分化成熟とインスリンシグナルを制御している2013
- Author(s)
  井ノ口仁一、永福正和
- Organizer
  第32回日本糖質学会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] T細胞分化制御機構および免疫疾患におけるスフィンゴ糖脂質発現の意義2013
- Author(s)
  永福正和、大野勲、鈴木明身、井ノ口仁一
- Organizer
  第11回糖鎖科学コンソーシアムシンポジウム
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] マクロファージは内臓脂肪細胞のスフィンゴ糖脂質発現を制御し、脂肪細胞の生理的分化成熟と肥満によるインスリン抵抗性を制御している
- Author(s)
  井ノ口仁一、永福正和
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス(大阪府東大阪市）
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] T細胞免疫におけるガングリオシド発現の意義
- Author(s)
  永福正和
- Organizer
  第78回日本生化学会東北支部例会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23370064
[Presentation] ガングリオシドは腸管におけるNPC1L1を介したコレステロール吸収を制御する
- Author(s)
  二瓶渉, 永福正和, 菊地唯, 井ノ口仁一
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25840040
[Presentation] Rearrangements of lipid raft constituents during thymocyte development
- Author(s)
  永福正和、豊島かおる、井ノ口仁一
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25840040

1. INOKUCHI Jin-ichi (70131810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. UEMURA Satoshi (10399975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. GO Shinji (10458218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 井口仁一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 大野勲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAFUKU Masakazu 永福 正和

Research Projects

Research Products

Co-Researchers

Role of membrane gangliosides in T cell development and activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Emerging pathophysiological roles of ganglioside GM3

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Glycoscience: Biology and Medicine (Gangliosides in T cell immunity)2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Sugar Chains (Gangliosides and T cell immunity)2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Control of Homeostatic and Pathogenic Balance in Adipose Tissue by Ganglioside GM32015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct selectivity of gangliosides required for CD4+ T and CD8+ T cell activation2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Physiological Significance of Ganglioside Species Selectively Expressed on Individual T Cell Subsets2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Heterogeneity of gangliosides among T cell subsets2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneity of gangliosides among T cell subsets2013

Author(s)

Journal Title

Data Source

[Journal Article] CD4+T細胞とCD8+T細胞の活性化におけるラフトガングリオシドの相違2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] CD4 and CD8 T cells require different membrane gangliosides for activation2012

Author(s)

Journal Title

Data Source

[Journal Article] CD4 and CD8 T cells require different membrane gangliosides for activation2012

Author(s)

Journal Title

DOI

Data Source

[Patent] ヘルパーT細胞の選択的機能制御法

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Data Source

[Patent] 高脂血症治療剤のスクリーニング方法

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Data Source

[Presentation] マクロファージによる内臓脂肪細胞のガングリオシド発現の病態生理学的意義2013

Author(s)

Organizer

NAGAFUKU Masakazu 永福正和