Kawano Yohei 河野洋平

… Alternative Names

KAWANO Youhei 河野洋平

河野洋平カワノヨウヘイ

Less

Researcher Number	20401383
Other IDs	https://orcid.org/0000-0001-7181-2282
Affiliation (Current)	2024: 広島大学, 医系科学研究科(医), 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 広島大学, 医系科学研究科(医), 准教授 2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2012: 東京医科歯科大学, 大学院・医歯学・総合研究科, 助教 2011 – 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 2009 – 2010: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 … More 2007: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助手 2006: 東京医科歯科大学, 歯学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / Basic Section 54010:Hematology and medical oncology-related / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Experimental pathology
Keywords	Principal Investigator pre-BCR / リソソーム / プレB細胞 / BCR / 造血前駆細胞 / B7ファミリー / タンパク分解 / レパートリー / BLNK / B細胞 / プレB … More Except Principal Investigator … More T細胞 / 免疫抑制御 / 慢性炎症 / 制御細胞 / 免疫チェックポイント分子 / 口腔癌 / 口腔粘膜 / 免疫制御 / 系列特異的細胞消去 / 緑色蛍光色素 / ジフテリア毒素 / 相同組み換え / トランスジェニックマウス / 好塩基球 Less

リンパ系から由来する単球／マクロファージの生理的意義の解明Principal Investigator
- Principal Investigator
  
  河野洋平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hiroshima University
Functional analysis of B7-like protein ILDR2Principal Investigator
- Principal Investigator
  
  Kawano Yohei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima University
Dynamics of immune regulation in oral chronic inflammation and cancer, and their connection to systemic immunity
- Principal Investigator
  
  Azuma Miyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tokyo Medical and Dental University
The role for Laptm5 in the down-modulation of pre-B cell receptorPrincipal Investigator
- Principal Investigator
  
  KAWANO Youhei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
Tne regulation mechanism of pre-B cell receptor expression and pre-B acute lymphoblastic lymphomagenesisPrincipal Investigator
- Principal Investigator
  
  KAWANO Youhei
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
系列特異的細胞消去法を応用した免疫細胞の生体内機能解析
- Principal Investigator
  
  烏山一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University
プレB細胞レセプターの発現調節機構の解明Principal Investigator
- Principal Investigator
  
  河野洋平
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University

All 2022 2020 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 臨床免疫・アレルギー科プレB細胞レセプターの新たな役割2006
- Author(s)
  河野洋平
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18790335
[Journal Article] VSIG4/CRIg directly regulates early CD8+ T cell activation through its counter-receptor in a narrow window.2022
- Author(s)
  Widyagarini A, Nishii N, Kawano Y, Zhang C, Azuma M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 614 Pages: 100-106
- DOI
  10.1016/j.bbrc.2022.04.120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09902
[Journal Article] Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting.2020
- Author(s)
  Yang Y, Nagai S, Kang S, Xia Y, Kawano Y, Miyake K, Karasuyama H, Azuma M.
- Journal Title
  
  International Immunology
  
  Volume: - Issue: 8 Pages: 509-518
- DOI
  10.1093/intimm/dxaa014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-18K15180, KAKENHI-PROJECT-19H01025
[Journal Article] CEACAM1 specifically suppresses B cell receptor signaling-mediated activation..2020
- Author(s)
  Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Shuang Wang, Yasuhiro Nemoto, Shigeru Oshima, Takeshi Tsubata, Takahiro Adachi, Yohei Kawano, Mamoru Watanabe, Richard S. Blumberg, Ryuichi Okamoto, Takashi Nagaishi.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 535 Pages: 99-105
- DOI
  10.1016/j.bbrc.2020.11.126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-20K09902
[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012
- Author(s)
  Yohei Kawano
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32 Issue: 21 Pages: 4462-4471
- DOI
  10.1128/mcb.00531-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-23790530, KAKENHI-PROJECT-24659225
[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012
- Author(s)
  Kawano, Y., Ouchida, R., Wang
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 32 Pages: 4462-71
- Data Source
  KAKENHI-PROJECT-23790530
[Journal Article] Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.2010
- Author(s)
  Wada T, Ishiwata K, Koseki H, Ishikura T, Ugajin T, Ohnuma N, Obata K, Ishikawa R, Yoshikawa S, Mukai K, Kawano Y, Minegishi Y, Yokozeki H, Watanabe N, Karasuyama H.
- Journal Title
  
  J Clin Invest. 120(8)
  
  Pages: 2867-2875
- Data Source
  KAKENHI-PROJECT-21790461
[Journal Article] IgG-mediated systemic anaphylaxis toprotein antigen can be induced evenunder conditions of limited amounts of antibody and antigen.2010
- Author(s)
  Ishikawa R, Tsujimura Y, Obata K, Kawano Y, Minegishi Y, Karasuyama H.
- Journal Title
  
  Biochem Biophys Res Commun. 402(4)
  
  Pages: 742-746
- Data Source
  KAKENHI-PROJECT-21790461
[Journal Article] Basophils preferentially expressmouse Mast Cell Protease 11 among the mast cell tryptase family incontrast to mast cells.2009
- Author(s)
  Ugajin T, Kojima T, Mukai K, ObataK, Kawano Y, Minegishi Y, Eishi Y,Yokozeki H, Karasuyama H.
- Journal Title
  
  J Leukoc Biol. 86(6)
  
  Pages: 1417-1425
- Data Source
  KAKENHI-PROJECT-21790461
[Journal Article] Basophils play a pivotal role in immunoglobulin G- but not immunoglobulin E-mediated systemic anaphylaxis.2008
- Author(s)
  Tsujimura, Y., Obata, K., Mukai, K., Shindou, H., Yoshida, M., Nishikado, H., Kawano, Y., Minegishi, Y., Shimizu, T. and Karasuyama, H.
- Journal Title
  
  Immunity (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659109
[Journal Article] Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.2008
- Author(s)
  Yasuda, T., Sanjo, H., Pages, G., Kawano, Y., Karasuyama, H. Pouyssegur, J., Ogata, M. and Kurosaki, T.
- Journal Title
  
  Immunity (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659109
[Journal Article] Basophils are essential initiators of a novel type of chronic allergic inflammation.2007
- Author(s)
  Obata, K., Mukai, K., Tsujimura, Y., Ishiwata, K., Kawano, Y., Minegishi, Y., Watanabe, N., and Karasuyama, H.
- Journal Title
  
  Blood 110
  
  Pages: 913-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659109
[Journal Article] BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces κ gene rearrangement.2006
- Author(s)
  Yamamoto, M., Hayashi, K., Nojima, T., Matsuzaki, Y., Kawano, Y., Karasuyama, H., Goitsuka, R., Kitamura D.
- Journal Title
  
  Blood 108
  
  Pages: 2703-2711
- Data Source
  KAKENHI-PROJECT-18659109
[Journal Article] PreB cell receptor assesses the quality of IgH chains and tunes the preB cell repertoire by delivering differential signals.2006
- Author(s)
  Kawano, Y., Yoshikawa, S., Minegishi, Y., Karasuyama, H.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 2242-2249
- Data Source
  KAKENHI-PROJECT-18659109
[Journal Article] Pre-B cell receptor assesses the quality of IgH chains and tunes the pre-B cell repertoire by delivering diffent signals.2006
- Author(s)
  河野洋平
- Journal Title
  
  Journal of Immunology 177巻4号
  
  Pages: 2242-2249
- Data Source
  KAKENHI-PROJECT-18790335
[Presentation] VSIG4/CRIg, a new B7 family ligand, directly regulates early CD8+ T cell activation through its counter-receptor in a narrow window2022
- Author(s)
  Amrita Widyagarini, Yohei Kawano, Chenyang Zhang, Miyuki Azuma
- Organizer
  The 51th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-20K09902
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 52013
- Author(s)
  Kawano, Y., Ouchida, R., O-Wang, J., Yoshikawa, S., Yamamoto, M., Kitamura, D., Karasuyama, H.
- Organizer
  Keystone Symposia-B cell development and function
- Place of Presentation
  Keystone, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23790530
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane2013
- Author(s)
  Yohei Kawano
- Organizer
  Keystone Symposia-B cell development and function
- Place of Presentation
  Keystone, colorado, USA
- Data Source
  KAKENHI-PROJECT-23790530
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated proteintransmembrane 52012
- Author(s)
  Kawano, Y., Ouchida, R., O-Wang, J., Yoshikawa, S., Yamamoto, M., Kitamura, D., Karasuyama, H.
- Organizer
  The 35th MBSJ annualmeeting.
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-23790530
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane2012
- Author(s)
  Yohei Kawano
- Organizer
  The 35th MBSJ annual meeting
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-23790530
[Presentation] Laptm5 down-modulates pre-B cell receptor in anautophagy-independent manner2011
- Author(s)
  Kawano, Y., Ouchida, R., O-Wang, J., Yoshikawa, S., Yamamoto, M., Kitamura, D., Karasuyama, H.
- Organizer
  The 41th JSI annual meeting.
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-23790530
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression through BLNK-mediated induction of LAPTM52010
- Author(s)
  河野洋平
- Organizer
  国際免疫学会2010
- Place of Presentation
  神戸
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790461
[Presentation] A novel mechanism for the autonomous termination of pre-Bcell receptor expression through BLNK-mediated induction of LAPTM5.2010
- Author(s)
  Kawano Y., Ouchida R, O-Wang Jiyang, Yoshikawa S, Yamamoto M., Kitamura D., Karasuyama H.
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  Kobe
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790461
[Presentation] A novel mechanism for the autonomous termination of pre-Bcell receptor expression through BLNK-mediated induction of LAPTM5.2009
- Author(s)
  Kawano Y., Ouchida R, O-Wang Jiyang, Yoshikawa S, Yamamoto M., Kitamura D., Karasuyama H.
- Organizer
  The 39th JSI annual meeting.
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-21790461
[Presentation] A novel mechanism for the autonomous termination of pre-B cell receptor expression through BLNK-mediated induction of LAPTM52009
- Author(s)
  河野洋平
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21790461
[Presentation] 好塩基球が中心的な役割を果たすIgG依存性全身性アナフィラキシー2007
- Author(s)
  辻村祐佑、河野洋平、峯岸克行、烏山一
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Identification and characterization of murine basophil granular enzymes mMCP-8 and mMCP-112007
- Author(s)
  Ugajin T, Kojima T, Obata K, Tsujimura Y, Mukai K, Kawano Y, Yokozeki H, Minegishi Y, Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Molecular mechanism of BASH-mediated preBCR down-regulation.2007
- Author(s)
  河野洋平
- Organizer
  日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18790335
[Presentation] 好塩基球に選択的に発現する穎粒酵素に対する特異抗体の樹立とその応用2007
- Author(s)
  宇賀神つかさ、小島利之、小畑一茂、辻村祐佑、向井香織、河野洋平、峯岸克行、烏山一
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Molecular mechanism of BASH-mediated preBCR down-regulation2007
- Author(s)
  Kawano Y, Yamamoto M, Kitamura D. and Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Basophils function as initiator rather than effectors in IgE-mediated chronic allergic inflammation2007
- Author(s)
  Mukai K, Kawano Y, Minegishi Y, Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Basophils function as an initiator of chronic allergic inflammation.2007
- Author(s)
  Karasuyama H, Mukai K, Obata K, Tsujimura Y, Kawano Y, Ishiwata K, Watanabe N, and Minegishi Y.
- Organizer
  The 20th Naito Conference
- Place of Presentation
  Kanagawa
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Basophils and mast cells play distinct roles in systemic anaphylaxis.2007
- Author(s)
  Karasuyama H, Tsujimura Y, Obata K, Mukai K, Kojima T, Nishikado H, Kawano Y, Minegishi Y.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] CD200R3 functions as an activating receptor expressed exclusively on basophils and a subset of a mast cells2007
- Author(s)
  Obata K, Kojima T, Tsujimura Y, Kawano Y, Minegishi Y. and Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Basophils function as initiators rather than effectors in IgE-mediated chronic allergic inflammation, independently of T cells and mast cells.2007
- Author(s)
  Karasuyama H, Mukai K, Obata K, Ishiwata K, Watanabe N, Kawano Y, Minegishi Y.
- Organizer
  The 94th annual meeting of the American Association of Immunologists.
- Place of Presentation
  Miami.
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] Basophils play a piovotal role in IgG-but not IgE-mediated systemic anaphylaxis2007
- Author(s)
  Tsujimura Y, Kawano Y, Minegishi Y, and Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] PreBCR positively selects phosphatidylcholine-reactive V_H11-μH chains during B cell ontogeny in fetal liver2007
- Author(s)
  Yoshikawa S, Kawano Y, Minegishi Y, and Karasuyama H.
- Organizer
  The 37th JSI annual meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18659109
[Presentation] LAPTM5 down-modulates pre-B cell receptor in an autophagy-independent manner
- Author(s)
  河野洋平
- Organizer
  第４０回日本免疫学会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-23790530

1. Azuma Miyuki (90255654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 烏山一 (60195013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
3. 米川博通 (30142110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 永井重徳 (50348801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 大野建州 (80435635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 永石宇治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 鬼澤道夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawano Yohei 河野 洋平

KAWANO Youhei 河野 洋平

河野 洋平 カワノ ヨウヘイ

Research Projects

Research Products

Co-Researchers

リンパ系から由来する単球／マクロファージの生理的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of B7-like protein ILDR2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamics of immune regulation in oral chronic inflammation and cancer, and their connection to systemic immunity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role for Laptm5 in the down-modulation of pre-B cell receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tne regulation mechanism of pre-B cell receptor expression and pre-B acute lymphoblastic lymphomagenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

系列特異的細胞消去法を応用した免疫細胞の生体内機能解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プレB細胞レセプターの発現調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床免疫・アレルギー科プレB細胞レセプターの新たな役割2006

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] VSIG4/CRIg directly regulates early CD8+ T cell activation through its counter-receptor in a narrow window.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CEACAM1 specifically suppresses B cell receptor signaling-mediated activation..2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012

Author(s)

Journal Title

Data Source

[Journal Article] Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.2010

Author(s)

Journal Title

Kawano Yohei 河野洋平

KAWANO Youhei 河野洋平

河野洋平カワノヨウヘイ