TAKEUCHI Shinji 武内伸治

… Alternative Names

武内伸治タケウチシンジ

Less

Researcher Number	20414287
Other IDs
Affiliation (Current)	2025: 北海道立衛生研究所, その他部局等, 主幹
Affiliation (based on the past Project Information) *help	2020 – 2021: 北海道立衛生研究所, その他部局等, 主幹 2019: 北海道立衛生研究所, 生活科学部, 主査 2018 – 2019: 北海道立衛生研究所, その他部局等, 主査 2017: 北海道立衛生研究所, 生活科学部, 主査 2014: 北海道立衛生研究所, 理化学部, 主査 … More 2012 – 2014: 北海道立衛生研究所, 理化学部, 主査(有害化学物質) 2011: 北海道立衛生研究所, 理化学部, 研究職員 2007 – 2010: 北海道立衛生研究所, 健康科学部, 研究職員 Less
Review Section/Research Field	Except Principal Investigator Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 64010:Environmental load and risk assessment-related / Hygiene and public health / Public health/Health science
Keywords	Except Principal Investigator 核内受容体 / 環境化学物質 / 化学物質 / 遺伝子発現 / 免疫毒性 / レポーターアッセイ / AhR / Th17 / ROR / レポーター遺伝子アッセイ … More / 環境保健 / 海洋汚染物質 / 核内受容体Nr4a / Foxp3 / Nr4a / 制御性T細胞 / 制御性Ｔ細胞 / ベンゾトリアゾール系UV吸収剤 / アリルハイドロカーボン受容体 / マイクロプラスチック / 迅速分析 / パッシブサンプラー / 作業環境 / PCBs / 室内環境 / レポータージーンアッセイ / パッシブサンプリング / 毛糸 / PCB / 環境 / 可塑剤 / 難燃剤 / ビスフェノール類 / ポリ塩化ビフェニル類 / 複合曝露 / 免疫 / 複合曝露影響 / ダイオキシン / 自己免疫疾患 / IL17 / IL-17 / サイトカイン / 早産 / 農薬 / 低出生体重 / 不育症 / 遺伝要因 / エピジェネティック要因 / 母子保健 / アンドロゲン受容体 / エストロゲン受容体 / 化学物質過敏症 / 室内空気 / シックハウス症候群 Less

Effects of microplastic-derived chemicals on functions of regulatory T cells via nuclear receptor Nr4a.
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Health Sciences University of Hokkaido
Study on the development of a method for rapidly sampling and analyzing PCBs in a room or working environment using yarns and risk evaluation
- Principal Investigator
  
  Anezaki Katsunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Hokkaido Research Organization
Effects of chemical mixtures contained in foods on immune response via nuclear receptors.
- Principal Investigator
  
  Kojima Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Hokkaido Institute of Public Health
Effects of environmental chemicals on Th17 cells differenciation via aryl hydrocarbon receptor
- Principal Investigator
  
  KOJIMA HIROYUKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health
Effects of environmental chemicals on differentiation of helper-T 17 cells via retinoic acid receptor-related orphan receptors
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health
化学物質に対する胎児・小児の脆弱性に係わる遺伝・エピジェネティック要因の解明
- Principal Investigator
  
  佐田文宏
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  National Institute of Public Health
Effects of Indoor Air Chemicals on Transcriptional Activities via Nuclear Receptors and Dioxin Receptor
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health

[Journal Article] An analytical survey of benzotriazole UV stabilizers in plastic products and their endocrine-disrupting potential via human estrogen and androgen receptors2021
- Author(s)
  Sakuragi Yuuta、Takada Hideshige、Sato Hiroya、Kubota Atsuhito、Terasaki Masaru、Takeuchi Shinji、Ikeda-Araki Atsuko、Watanabe Yoko、Kitamura Shigeyuki、Kojima Hiroyuki
- Journal Title
  
  Science of The Total Environment
  
  Volume: 800 Pages: 149374-149374
- DOI
  10.1016/j.scitotenv.2021.149374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Distribution of 58 Semi-Volatile Organic Chemicals in the Gas Phase and Three Particle Sizes in Indoor Air and House Dust in Residential Buildings During the Hot Season in Japan2019
- Author(s)
  Shinji Takeuchi,Toshiko Tanaka-Kagawa, Ikue Saito, Hiroyuki Kojima, Hideto Jinno
- Journal Title
  
  BPB Reports
  
  Volume: 2 Pages: 91-98
- NAID
  130007940489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11686
[Journal Article] Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA12017
- Author(s)
  Takahashi Miki、Muromoto Ryuta、Kojima Hiroyuki、Takeuchi Shinji、Kitai Yuichi、Kashiwakura Jun-ichi、Matsuda Tadashi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 489 Issue: 4 Pages: 503-508
- DOI
  10.1016/j.bbrc.2017.05.181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08263, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791
[Journal Article] Effects of unintentional PCBs in pigments and chemical products on transcriptional activity via aryl hydrocarbon and nuclear hormone receptors2017
- Author(s)
  Shinji Takeuchi, Katsunori Anezaki, Hiroyuki Kojima
- Journal Title
  
  Environmental Pollution
  
  Volume: 227 Pages: 306-313
- DOI
  10.1016/j.envpol.2017.04.059
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26740032, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791
[Journal Article] Differential determination of plasticizers and organophosphorus flame retardants in residential indoor air in Japan.2016
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Ikue Saito, Hiroyuki Kojima, Kazuo Jin, Masayuki Satoh, Satoshi Kobayashi, Hideto Jinno
- Journal Title
  
  Environ. Sci. Pollut. Res.
  
  Volume: in press Issue: 8 Pages: 1-7
- DOI
  10.1007/s11356-015-4858-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-24390172
[Journal Article] Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Nele Van den Eede, Adrian Covaci
- Journal Title
  
  Toxicol. Lett.
  
  Volume: 245 Pages: 31-39
- DOI
  10.1016/j.toxlet.2016.01.004
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780
[Journal Article] A sensitive, rapid and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Shoji F. Nakayama, Takuya Shiozaki
- Journal Title
  
  Environ. Sci. Pollut. Res.
  
  Volume: in press Issue: 8 Pages: 1-7
- DOI
  10.1007/s11356-015-4662-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-24390172
[Journal Article] Review; A sensitive, rapid and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples.2015
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Shoji F. Nakayama, and Takuya Shiozaki
- Journal Title
  
  Environmental Science and Pollution Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590773
[Journal Article] Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors alpha and gamma.2015
- Author(s)
  Hiroyuki Kojima, Yukimasa Takeda, Ryuta Muromoto, Miki Takahashi, Toru Hirao, Shinji Takeuchi, Anton M Jetten, and Tadashi Matsuda
- Journal Title
  
  Toxicology
  
  Volume: 329 Pages: 32-39
- DOI
  10.1016/j.tox.2015.01.007
- NAID
  120005712473
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25460056, KAKENHI-PROJECT-24390172
[Journal Article] Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.2015
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Seigo Sanoh, Kazumi Sugihara, Shigeyuki Kitamura, and Shigeru Ohta
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 282 Issue: 2 Pages: 119-128
- DOI
  10.1016/j.taap.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] Detection of 34 plasticizers and 25 flame retardants in indoor air from houses in Sapporo, Japan.2014
- Author(s)
  Takeuchi S, Kojima H, Saito I, Jin K, Kobayashi S, Tanaka-Kagawa T, Jinno H.
- Journal Title
  
  Sci Total Environ
  
  Volume: in progress Pages: 1-8
- DOI
  10.1016/j.scitotenv.2014.04.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] Simple and rapid determination of PCDD/Fs in flue gases from various waste incinerators in China using DR-EcoScreen cells.2014
- Author(s)
  Zhou Z, Zhao B, Kojima H, Takeuchi S, Takagi Y, Tateishi N, Iida M, Shiozaki T, Xu P, Qi L, Ren Y, Li N, Zheng S, Zhao H, Fan S, Zhang T, Liu A, Huang Y.
- Journal Title
  
  Chemosphere
  
  Volume: 102 Pages: 24-30
- DOI
  10.1016/j.chemosphere.2013.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] イソフラボン類のIL-17産生増強作用2013
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田　正
- Journal Title
  
  ImmunoTox Letter (日本免疫毒性学会誌)
  
  Volume: 18（2） Pages: 12-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590773
[Journal Article] In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors.2013
- Author(s)
  Kojima H, Takeuchi S, Itoh T, Iida M, Kobayashi S, Yoshida T.
- Journal Title
  
  Toxicology
  
  Volume: 314 Issue: 1 Pages: 76-83
- DOI
  10.1016/j.tox.2013.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptorsαandγ2012
- Author(s)
  Kojima H, Muromoto R, Takahashi M, Takeuchi S, Takeda Y, Jetten AM, and Matsuda T.
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 259 Issue: 3 Pages: 338-345
- DOI
  10.1016/j.taap.2012.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675, KAKENHI-PROJECT-23390015, KAKENHI-PROJECT-23790067
[Journal Article] Comparative Study of Human and Mouse Pregnane X Receptor Agonistic Activity in 200 Pesticides Using Reporter Gene Assays2011
- Author(s)
  Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai
- Journal Title
  
  Toxicology
  
  Volume: VOL.280 Pages: 77-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Determination of Dioxin Concentrations in Fish and Seafood Samples Using a Highly Sensitive Reporter Cell Line, DR-EcoScreen Cells2011
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Tomoaki Tsutsumi, Katsuyuki Yamaguchi, Katsunori Anezaki, Keiko Kubo, Mitsuru Iida, Tetsuo Takahashi, Satoshi Kobayashi, Kazuo Jin, Tadanori Nagai
- Journal Title
  
  Chemosphere
  
  Volume: VOL.83 Pages: 753-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2011
- Author(s)
  Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K and Kojima H.
- Journal Title
  
  Toxicology
  
  Volume: 280 Issue: 2-3 Pages: 112-121
- DOI
  10.1016/j.tox.2011.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675, KAKENHI-PROJECT-22510071
[Journal Article] Determination of dioxin concentrations in fish and seafood samples using a highly sensitive reporter cell line, DR-EcoScreen cells2011
- Author(s)
  Kojima H, Takeuchi S, Tsutsumi T, Yamaguchi K, Anezaki K, Kubo K, Iida M, Takahashi T, Kobayashi S, Jin K and Nagai T.
- Journal Title
  
  Chemosphere
  
  Volume: 83 Issue: 6 Pages: 753-759
- DOI
  10.1016/j.chemosphere.2011.02.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using reporter gene assays2011
- Author(s)
  Kojima H, Sata F, Takeuchi S, Sueyoshi T and Nagai T.
- Journal Title
  
  Toxicology
  
  Volume: 280 Issue: 3 Pages: 77-87
- DOI
  10.1016/j.tox.2010.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] 水性塗料成分1-メチル-2-ピロリドン及びテキサノールによる新築小学校の室内空気汚染2010
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫、秋津裕志、伊佐治信一
- Journal Title
  
  日本室内環境学会誌 (掲載確定, 印刷中)
- NAID
  40017162386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] [Minireview]Endocrine-disrupting Potential of Pesticides via Nuclear Receptors and Aryl Hydrocarbon Receptor2010
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Tadanori Nagai
- Journal Title
  
  Journal of Health Science (掲載確定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] 農薬による核内受容体RORα/γを介したIL-17遺伝子発現に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Journal Title
  
  ImmunoTox Letter(日本免疫毒性学会)
  
  Volume: 15(2) Pages: 4-6
- URL
  http://www.immunotox.org/immunotoxletter/pdf/30vol15no2-2010J.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Endocrine-disrupting potential of pesticides via nuclear receptors and aryl hydrocarbon receptor2010
- Author(s)
  Kojima H, Takeuchi S. and Nagai T.
- Journal Title
  
  J. Health Sci.
  
  Volume: 56(4) Pages: 374-386
- NAID
  130000303536
- URL
  https://www.jstage.jst.go.jp/article/jhs/56/4/56_4_374/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells.2009
- Author(s)
  Kojima H., Takeuchi S., Uramaru N., Sugihara K., Yoshida T., and Kitamura S.
- Journal Title
  
  Environmental Health Perspectives (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Journal Title
  
  Environmental Health Perspectives
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Journal Title
  
  Environmental Health Perspectives VOL.117
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T. and Kitamura S.
- Journal Title
  
  Environ. Health Perspect
  
  Volume: 117 Issue: 8 Pages: 1210-1218
- DOI
  10.1289/ehp.0900753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Application of a bioassay using DR-EcoScreen cells to the determination of dioxins in ambient air : A comparative study with HRGC-HRMS analysis2009
- Author(s)
  Anezaki K, Yamaguchi K, Takeuchi S, Iida M, Jin K. and Kojima H.
- Journal Title
  
  Environ. Sci. Technol
  
  Volume: 43 Issue: 19 Pages: 7478-7483
- DOI
  10.1021/es901003b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative Study on the Nuclear Hormone Receptor Activity of Various Phytochemicals and Their Metabolites by Reporter Gene Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Shinji Takeuchi, Tetsuo Takahashi, Yukiharu Sawada, Mitsuru Iida, Tadashi Matsuda, Hiroyuki Kojima
- Journal Title
  
  Biological & Pharmaceutical Bulletin 32(2)
  
  Pages: 195-202
- NAID
  110007042163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Application of a Bioassay Using DR-EcoScreen Cells to the Determination of Dioxins in Ambient Air : A Comparative Study with HRGC-HRMS Analysis2009
- Author(s)
  Katsunori Anezaki, Katsuyuki Yamaguchi, Shinji Takeuchi, Mitsuru Iida, Kazuo Jin, Hiroyuki Kojima
- Journal Title
  
  Environmental Science & Technology VOL.43
  
  Pages: 7478-7483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative study on the nuclear hormone receptor activity of various phytochemicals and their metabolites by reporter gene assays using Chinese hamster ovary cells.2009
- Author(s)
  Takeuchi S., Takahashi T., Sawada Y., Iida M., Matsuda T., and Kojima H.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 32
  
  Pages: 195-202
- NAID
  110007042163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.2008
- Author(s)
  Takeuchi S., Iida M., Yabushita H., Matsuda T., and Kojima H.
- Journal Title
  
  Chemosphere 74
  
  Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] In Vitro Screening for Aryl Hydrocarbon Receptor Agonistic Activity in 200 Pesticides Using a Highly Sensitive Reporter Cell Line, DR-EcoScreen Cells, and in Vivo Mouse Liver Cytochrome P450-1A Induction by Propanil, Diuron and Linuron2008
- Author(s)
  Shinji Takeuchi, Mitsuru Iida, Hisatoshi Yabushita, Tadashi Matsuda, Hiroyuki Kojima
- Journal Title
  
  Chemosphere 74
  
  Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] 改修工事に伴いシックハウス症候群が発生したマンションにおける室内空気中化学物質の測定と症状誘発に関与した物質の推定2007
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫、渡辺一彦
- Journal Title
  
  北海道立衛生研究所報 57
  
  Pages: 23-28
- NAID
  120006794425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Determination of dioxins in emission gas, ash and atomospheric air samples using a highly sensitive AhR-mediated reporter cell line, DR-EcoScreen cells.2007
- Author(s)
  Kojima H., Takeuchi S., Anezaki K., Yamaguchi K., Otsuka H., Sawadaishi K., Honda K., Yabushita H., and Iida M.
- Journal Title
  
  Organohalogen Compounds 69
  
  Pages: 1234-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] 化学物質過敏症患者の症状に関与する室内空気中化学物質の検索(第3報)2007
- Author(s)
  武内伸治、小島弘幸、小林智、高橋哲夫
- Journal Title
  
  北海道立衛生研究所報 57
  
  Pages: 29-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] マイクロプラスチック由来化学物質におけるヒトエストロゲン受容体alpha/betaアゴニスト活性の比較2020
- Author(s)
  桜木優太、寺崎将、武内伸治、小島弘幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Effects of perfluorocarboxylic acids on transcriptional activity via human nuclear receptors and gene expression in human macrophage-like THP-1 cells.2019
- Author(s)
  Kojima H, Takeuchi S, Okuda K, Muromoto R, Kishi R, Araki A.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Distribution of 58 semi-volatile organic chemicals in the gas phase and three particle sizes in indoor air and house dust in residential buildings during the hot season in japan.2019
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Ikue Saito, Hiroyuki Kojima, Hideto Jinno
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11686
[Presentation] Distribution of 58 semi-volatile organic chemicals in the gas phase and three particle sizes in indoor air and house dust in residential buildings during the hot season in Japan.2019
- Author(s)
  Takeuchi S, Tanaka-Kagawa T, Saito I, Kojima H, Jinno H.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] 毛糸を用いた室内・作業環境中PCBの迅速採取分析法の開発2019
- Author(s)
  姉崎克典、武内伸治、中野武
- Organizer
  2019年室内環境学会学術大会
- Data Source
  KAKENHI-PROJECT-18K11686
[Presentation] Effects of essential oil constituents on in vitro transcriptional activities via estrogen and androgen receptors, and in silico molecular docking study.2018
- Author(s)
  Takeuchi S, Okuda K, Sugihara K, Kojima H.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 精油成分の女性ホルモン受容体及び男性ホルモン受容体を介した作用及び分子結合シミュレーションによる評価2018
- Author(s)
  武内伸治、奥田勝博、杉原数美、小島弘幸
- Organizer
  環境疫学及び曝露科学に関する国際会議における2018年アジア支部会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11686
[Presentation] In vitro and in silico studies on PPARalpha/gamma and PXR activation by di-(2-ethylhexyl) phthalate and its metabolites.2018
- Author(s)
  Kojima H, Okuda K, Uramaru N, Kitamura S, Takeuchi S, Muromoto R, Sugihara K, Kishi R, Araki A.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Effects of photopolymerization initiators on in vitro transcriptional activities via nuclear receptors.2017
- Author(s)
  Takeuchi S, Kojima H.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] C/TOF-MS及び薬物受容体アッセイを用いた危険ドラッグ成分のスクリーニング2017
- Author(s)
  武内伸治、佐藤正幸、小島弘幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市（仙台国際センター）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Characterization of the endocrine disruption potential of bisphenol A structural analogues via human nuclear receptors.2017
- Author(s)
  Kojima H, Takeuchi S, Sanoh S, Kitamura S, Uramaru N, Sugihara K, Yoshinari K.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] ヒトマクロファージ様THP-1細胞の遺伝子発現に及ぼすDEHPとMEHPの曝露影響2017
- Author(s)
  小島弘幸、武内伸治、室本竜太、岸玲子、荒木敦子
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Biochanin Aによる核内受容体RORgamma活性化機構の解析2017
- Author(s)
  室本竜太、高橋美妃、小島弘幸、武内伸治、松田正
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] ffects of unintentional PCBs in pigments and chemical products on transcriptional activity via 10 nuclear receptors and aryl hydrocarbon receptor.2016
- Author(s)
  Shinji Takeuchi, Katsunori Anezaki, Hiroyuki Kojima
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe (Japan)
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 危険ドラッグの迅速検知に向けたバイオアッセイ系について2016
- Author(s)
  小島弘幸、武内伸治
- Organizer
  第68回北海道公衆衛生学会
- Place of Presentation
  札幌市（札幌市立大学桑園キャンパス）
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 生活用品等に含まれる精油成分の性ホルモン受容体を介した作用2016
- Author(s)
  武内伸治、佐藤正幸、小林智、小島弘幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Characterization of thyroid hormone receptor and retinoid X receptor activities in 100 hydroxylated polychlorinated biphenyls using CHO-K1 cell-based transactivation assays.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fujio Shiraishi, Hiroaki Kuroki, Shigeyuki Kitamura
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe (Jaoan)
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Comparison of the forms of plasticizers and organophosphorus flame retardants present in residential indoor air in different seasons.2016
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Masayuki Sato, Satoshi Kobayashi, Hiroyuki Kojima, Ikue Saito, Hitoshi Uemura, Hideto Jinno
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Sapporo (Japan)
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Comparative study on the in vitro nuclear receptor activities of di-(2-ethylhexyl) phthalate and its five metabolites.2016
- Author(s)
  Hiroyuki Kojima, Naoto Uramaru, Shigeyuki Kitamura, Shinji Takeuchi S, Reiko Kishi, Atsuko Araki
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Sapporo (Japan)
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] パーソナルケア製品に含まれる化学物質によるERalpha/beta及びPXRを介した内分泌撹乱活性2015
- Author(s)
  渡部容子、小島弘幸、武内伸治、藤本成明、北村繁幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌市（札幌コンベンションセンター）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 色素や化成品に含まれるPCBの核内受容体及びダイオキシン受容体を介した作用2015
- Author(s)
  武内伸治、姉崎克典、小島弘幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌市（札幌コンベンションセンター）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 核内受容体の転写活性化を介した新規甲状腺ホルモンかく乱機構の解析2015
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の測定2015
- Author(s)
  武内伸治、香川（田中）聡子、斎藤育江、小島弘幸、佐藤正幸、小林智、神野秀人
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 肝肥大誘導性ペルフルオロオクタン酸とその類縁化合物によるヒト及びラット核内受容体活性の比較2014
- Author(s)
  小島弘幸、武内伸治、中島宏之、野表知世、藤野智恵理、浦丸直人、北村繁幸、吉成浩一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス他(熊本市)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 居住住宅における室内空気中の可塑剤及び有機リン系難燃剤の分別定量2014
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林　智、小島弘幸、斎藤育江、上村　仁、田中(香川)聡子、神野透人
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス他(熊本市)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Effects of perfluoroalkylcarboxylic acids and phthalate metabolite on transcriptional activity via PPARA and PPARA-V227A variant2013
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Kenichi Takahashi, Fumihiro Sata
- Organizer
  The 8th World Conference on Developmental Origins of Health and Diseases (DOHaD 2013)
- Place of Presentation
  SUNTEC Singapore (Singapore)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Detection of 34 plasticizers and 25 flame retardants in indoor air from houses in Sapporo, Japan2013
- Author(s)
  Shinji Takeuchi, Hiroyuki Kojima, Ikue Saito, Kazuo Jin, Satoshi Kobayashi, Toshiko Tanaka-Kagawa, Hideto Jinno
- Organizer
  33th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2013)
- Place of Presentation
  Hotel Inter-Burgo, Daegu (Republic of Korea)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] イソフラボン類によるSTAT3とRORgammaを介したIL-17産生増強作用2013
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田　正
- Organizer
  第20回日本免疫毒性学会
- Place of Presentation
  東海大学代々木キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Effects of environmental chemicals on interleukin-17 production via aryl hydrocarbon receptor2013
- Author(s)
  Hiroyuki Kojima, Ryuta Muromoto, Miki Takahashi, Shinji Takeuchi, Tadashi Matsuda
- Organizer
  33th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2013)
- Place of Presentation
  Hotel Inter-Burgo, Daegu (Republic of Korea)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2012
- Author(s)
  Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K and Kojima H.
- Organizer
  The 51st Annual Meeting of the Society of Toxicology(SOT)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 環境化学物質における核内受容体RORα/γ活性の探索とIL-17遺伝子発現への影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 炎症性サイトカインIL-17産生に及ぼすBiochanin Aの影響に関する研究2012
- Author(s)
  高橋美妃、室本竜太、小島弘幸、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptorsαandγ2012
- Author(s)
  Kojima H, Muromoto R, Takahashi M, Takeuchi S, Takeda Y, Jetten AM, and Matsuda T.
- Organizer
  The 51st Annual Meeting of the Society of Toxicology(SOT)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中から検出された光重合開始剤及びその類似化合物の核内受容体を介した作用2012
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ2012
- Author(s)
  Hiroyuki Kojima, Ryuta Muromoto, Miki Takahashi, Shinji Takeuchi, Yukimasa Takeda, Anton M.Jetten, Tadashi Matsuda
- Organizer
  The 51st Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Francisco
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 環境化学物質における核内受容体RORα/γ活性の探索とIL-17遺伝子発現への影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 炎症性サイトカインIL-17産生に及ぼすBiochanin Aの影響に関する研究2012
- Author(s)
  高橋美妃、室本竜太、小島弘幸、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中から検出された光重合開始剤及びその類似化合物の核内受容体を介した作用2012
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2012
- Author(s)
  Shinji Takeuchi, Fujio Shiraishi, Shigeyuki Kitamura, Hiroaki Kuroki, Kazuo Jin, Hiroyuki Kojima
- Organizer
  The 51st Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Francisco
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORα/γ依存的なIL-17産生に及ぼすBiochanin Aの影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京都(東京大学山上会館)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORγt依存的なIL-17遺伝子発現誘導に対するイソフラボン類の影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  第18回日本免疫毒性学会
- Place of Presentation
  千葉大学けやき会館(千葉市)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORγt依存的なIL-17遺伝子発現誘導に対するイソフラボン類の影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  第18回日本免疫毒性学会
- Place of Presentation
  千葉市(千葉大学けやき会館)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] トリクロサン及びその塩素化誘導体の13種類の核内受容体への作用2011
- Author(s)
  武内伸治、兼俊明夫、小林智、北村繁幸、小島弘幸
- Organizer
  日本薬学会第131年会総会
- Place of Presentation
  静岡市(ツインメッセ静岡)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORα/γ依存的なIL-17産生に及ぼすBiochanin Aの影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] トリクロサン及びその塩素化誘導体の13種類の核内受容体への作用2011
- Author(s)
  武内伸治、兼俊明夫、小林智、北村繁幸、小島弘幸
- Organizer
  日本薬学会第131年会総会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中化学物質における核内受容体活性のプロファイル2011
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  金沢市(金沢エクセルホテル東急)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中化学物質における核内受容体活性のプロファイル2011
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  金沢エクセルホテル東急(金沢市)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬200物質におけるレチノイド関連オーファン受容体(ROR)活性の探索とIL-17産生に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  第17回日本免疫毒性学会学術大会
- Place of Presentation
  国立環境研究所・大山記念ホール(つくば市)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ビスフェノールA関連物質の核内受容体PXR/CARを介した転写活性に及ぼす影響2010
- Author(s)
  小島弘幸、佐能正剛、武内伸治、杉原数美、北村繁幸
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  星薬科大学(東京都)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites Based on Transactivation Assays2010
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Organizer
  5th International Symposium on Brominated Flame Retardants
- Place of Presentation
  Kyoto University Clock Tower, Kyoto, Japan
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬による核内受容体RORα/γインバースアゴニスト活性と免疫系への影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京都(東京大学山上会館)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylarted and methoxylated metabolites based on transactivation assays2010
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T and Kitamura S.
- Organizer
  5th International Symposium on Brominated Flame Retardants
- Place of Presentation
  Kyoto University, Japan
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ビスフェノールA関連物質の核内受容体PXR/CARを介した転写活性に及ぼす影響2010
- Author(s)
  小島弘幸、佐能正剛、武内伸治、杉原数美、北村繁幸
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  東京都(星薬科大学)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬による核内受容体RORα/γインバースアゴニスト活性と免疫系への影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDE水酸化体の核内受容体アゴニスト及びアンタゴニスト活性2010
- Author(s)
  小島弘幸、武内伸治、杉原数美、浦丸直人、北村繁幸
- Organizer
  日本薬学会第130年会総会
- Place of Presentation
  桃太郎アリーナ(岡山市)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDE水酸化体の核内受容体アゴニスト及びアンタゴニスト活性2010
- Author(s)
  小島弘幸、武内伸治、杉原数美、浦丸直人、北村繁幸
- Organizer
  日本薬学会第130年会総会
- Place of Presentation
  岡山市(桃太郎アリーナ)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬200物質におけるレチノイド関連オーファン受容体(ROR)活性の探索とIL-17産生に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  第17回日本免疫毒性学会学術大会
- Place of Presentation
  つくば市(国立環境研究所・大山記念ホール)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸、武内伸治、佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDE及びそれら代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132例会
- Place of Presentation
  札幌市(札幌コンベンションセンター)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸、武内伸治、佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDEおよびその代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132回例会
- Place of Presentation
  札幌市(札幌コンベンションホール)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素化難燃剤PBDE及びそれら代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylarted and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T and Kitamura S.
- Organizer
  HORIBA International Conference/CDBIM Symposium : 21th Century Advances in the Molecular Toxicology of Environmental Chemicals and Pathogenesis of Disease
- Place of Presentation
  Tokyo University, Japan
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸, 武内伸治, 佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20659104
[Presentation] 植物由来化学物質における核内受容体PXR及びPPARα/β/γアゴニスト作用2009
- Author(s)
  武内伸治、飯田満、高橋哲夫、小島弘幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市(国立京都国際会館)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Organizer
  HORIBA International Conference/CDBIM Symposium : 21th Century Advances in the Molecular Toxicology of Environmental Chemicals and Pathogenesis of Disease
- Place of Presentation
  東京大学鉄門記念講堂(東京都)
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] PCB水酸化体100物質におけるグルココルチコイド受容体活性のスクリーニング2008
- Author(s)
  武内伸治、小島弘幸、神和夫、北村繁幸、黒木広明、白石不二雄
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京都(東京ビッグサイト)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 農薬200物質におけるヒト及びマウスPXRアゴニスト活性のスクリーニング2008
- Author(s)
  小島弘幸, 武内伸治, 佐田文宏, 根岸正彦
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京ビッグサイト(東京)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-20659104
[Presentation] 臭素系難燃剤ポリブロモジフェニルエーテル及びその代謝物における核内受容体活性のプロファイル2008
- Author(s)
  小島弘幸、武内伸治、浦丸直人、北村繁幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 脂溶性食品添加物における核内受容体活性のプロファイル2008
- Author(s)
  武内伸治、小島弘幸、松田正
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  熊本市(熊本市民会館)
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 植物由来機能成分の核内受容体を介した作用2008
- Author(s)
  武内伸治、小島弘幸、松田正、澤田幸治
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] シックハウス症候群の発症に関連する化学物質の検索システムの開発と実際例2008
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫
- Organizer
  日本分析化学会北海道支部2008冬季研究発表会
- Place of Presentation
  札幌市(北大学術交流会館)
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 有機リン系難燃剤における核内受容体活性のプロファイル2008
- Author(s)
  小島弘幸、武内伸治、小林智、伊藤俊弘、吉田貴彦
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  熊本市(熊本市民会館)
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 農薬200物質におけるヒト及びマウスPXRアゴニスト活性のスクリーニング2008
- Author(s)
  小島弘幸、武内伸治、佐田文宏、根岸正彦
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京都(東京ビッグサイト)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素系及び有機リン系難燃剤による核内受容体PXRの活性化2008
- Author(s)
  小島弘幸、武内伸治、小林智、伊藤俊弘、吉田貴彦
- Organizer
  第17回日本臨床環境医学会学術集会
- Place of Presentation
  旭川市(旭川ターミナルホテル)
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた大気中ダイオキシン類の測定(第2報)2008
- Author(s)
  姉崎克典、山口勝透、芥川智子、武内伸治、小島弘幸
- Organizer
  第17回環境化学討論会
- Place of Presentation
  神戸市(神戸国際会議場)
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた大気中ダイオキシン類の測定とAhR活性物質の同定2007
- Author(s)
  姉崎克典、山口勝透、芥川智子、小島弘幸、武内伸治、藪下尚智、飯田満
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] Determination of dioxins in emission gas, ash and atomospheric air samples using a highly sensitive AhR-mediated reporter cell line, DR-EcoScreen cells.2007
- Author(s)
  Kojima H., Takeuchi S., Anezaki K., Yamaguchi K., Otsuka H., Sawadaishi K., Honda K., Yabushita H., and Iida M.
- Organizer
  27th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた排出ガス及びばいじん中ダイオキシン類の測定2007
- Author(s)
  小島弘幸、武内伸治、山口勝透、大塚英幸、姉崎克典、澤田石一之、本田克久、藪下尚智、飯田満
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] シックスクールで検出された未規制化学物質(1-メチル-2-ピロリドン及びテキサノール)濃度の推移と発生源の探索2007
- Author(s)
  小林智、高橋哲夫、武内伸治、小島弘幸、神和夫
- Organizer
  平成19年度室内環境学会総会
- Place of Presentation
  仙台市(東北文化学園大学)
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] PCB水酸化体100物質におけるアンロゲン受容体活性のスクリーニング2007
- Author(s)
  武内伸治、小島弘幸、北村繁幸、黒木広明、白石不二雄
- Organizer
  第10回日本内分泌撹乱化学物質学会
- Place of Presentation
  さいたま市(大宮ソニックシティ)
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] PCB水酸化体100物質におけるエストロゲン受容体α/β活性のスクリーニング2007
- Author(s)
  武内伸治、小島弘幸、北村繁幸、黒木広明、白石不二雄
- Organizer
  フォーラム2007衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  大阪市(アピオ大阪森ノ宮ピロティホール)
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた魚介類中ダイオキシン類簡易測定法の開発2007
- Author(s)
  小島弘幸、武内伸治、堤智昭、山口勝透、高橋哲夫、小林智、藪下尚智、飯田満
- Organizer
  第10回日本内分泌撹乱化学物質学会
- Place of Presentation
  さいたま市(大宮ソニックシティ)
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 迅速で簡便な酵母を用いるAhRアゴニスト活性のアッセイ法について2007
- Author(s)
  武内伸治、白石不二雄、鎌田亮、中島大介、小島弘幸、滝上英孝、鈴木規之、白石寛明
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors alpha and gamma.
- Author(s)
  Hiroyuki Kojima, Yukimasa Takeda, Ryuta Muromoto, Miki Takahashi, Toru Hirao, Shinji Takeuchi, Anton M Jetten, and Tadashi Matsuda
- Organizer
  The 54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Year and Date
  2015-03-23 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Differential determination of plasticizers and organophosphorus flame retardants in residential indoor air.
- Author(s)
  Shinji Takeuchi, Kazuo Jin, Masayuki Sato, Satoshi Kobayashi, Hiroyuki Kojima, Ikue Saito, Hidenori Uemura, Toshiko Tanaka-Kagawa, Hideto Jinno
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds.
- Author(s)
  Hiroyuki Kojima, Seigo Sanoh, Shinji Takeuchi, Kazumi Sugihara, Koichi Yoshinari, Shigeyuki Kitamura
- Organizer
  The 54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Year and Date
  2015-03-23 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Comparative study on human and mouse nuclear receptor activities of hepatomegaly-inducing perfluorooctanoic acid and its related compounds.
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fumihiro Sata, Hiroyuki Nakajima, Chise Noomote, Chieri Fujino, Naoto Uramaru, Shigeyuki Kitamura, Koichi Yoshinari
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の分別定量（第２報）
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林智、小島弘幸、斎藤育江、上村仁、香川(田中)聡子、神野透人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Effects of metabolism of UV-absorbers by rat liver microsomes on their nuclear receptor activation.
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Seigo Sanoh, Shigeru Ohta, Shigeyuki Kitamura
- Organizer
  34th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2014)
- Place of Presentation
  Melia Castilla hotel (Madrid, Spain)
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体PXRおよびCAR転写活性に対する甲状腺ホルモン構造類似物質の影響
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Application of a bioassay using DR-EcoScreen cells to the determination of dioxins in environmental and food samples: comparative studies using HRGC-HRMS analysis.
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Takuya Shiozaki
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の分別定量
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林智、小島弘幸、斎藤育江、上村仁、香川(田中)聡子、神野透人
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773

1. KOJIMA Hiroyuki (10414286)

# of Collaborated Projects: 6 results

# of Collaborated Products: 126 results
2. MUROMOTO Ryuta (30455597)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
3. KOBAYASHI Satoshi (00414285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. YOSHIDA Takahiko (90200998)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. CHIBA Masahiro (90414292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ITOH Toshihiro (20271760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. MATSUDA Tadashi (20212219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. Anezaki Katsunori (20442634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 佐田文宏 (90187154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 鈴木智宏 (10414327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 浦丸直人 (90424069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 中野武 (00446791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 寺崎将 (10391195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. SUGANO Youhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OKUDA Katsuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

TAKEUCHI Shinji 武内 伸治

武内 伸治 タケウチ シンジ

Research Projects

Research Products

Co-Researchers

Effects of microplastic-derived chemicals on functions of regulatory T cells via nuclear receptor Nr4a.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the development of a method for rapidly sampling and analyzing PCBs in a room or working environment using yarns and risk evaluation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of chemical mixtures contained in foods on immune response via nuclear receptors.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of environmental chemicals on Th17 cells differenciation via aryl hydrocarbon receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of environmental chemicals on differentiation of helper-T 17 cells via retinoic acid receptor-related orphan receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

化学物質に対する胎児・小児の脆弱性に係わる遺伝・エピジェネティック要因の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of Indoor Air Chemicals on Transcriptional Activities via Nuclear Receptors and Dioxin Receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An analytical survey of benzotriazole UV stabilizers in plastic products and their endocrine-disrupting potential via human estrogen and androgen receptors2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distribution of 58 Semi-Volatile Organic Chemicals in the Gas Phase and Three Particle Sizes in Indoor Air and House Dust in Residential Buildings During the Hot Season in Japan2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA12017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of unintentional PCBs in pigments and chemical products on transcriptional activity via aryl hydrocarbon and nuclear hormone receptors2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential determination of plasticizers and organophosphorus flame retardants in residential indoor air in Japan.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A sensitive, rapid and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples.2016

Author(s)

Journal Title

TAKEUCHI Shinji 武内伸治

武内伸治タケウチシンジ