Okajima Tetsuya 岡島徹也

… Alternative Names

OKAJIMA Tetsuya 岡島徹也

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Researcher Number	20420383
Other IDs
External Links
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 教授 2025: 名古屋大学, 糖鎖生命コア研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 名古屋大学, 医学系研究科, 教授 2015 – 2017: 名古屋大学, 医学系研究科, 教授 2015: 名古屋大学, 医学(系)研究科(研究院), 教授 2011 – 2014: 名古屋大学, 医学(系)研究科(研究院), 准教授 2012: 名古屋大学, 医学系研究科, 准教授 … More 2010: Nagoya University, 医学系研究科, 准教授 2009 – 2010: Nagoya University, 大学院・医学系研究科, 准教授 2008: Nagoya University, 大学院・医学系研究科, 講師 2007: Nagoya University, 大学院・生命農学研究科, 助教 2006: 名古屋大学, 大学院生命農学研究科, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48040:Medical biochemistry-related / Functional biochemistry / Biological Sciences / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related / Applied molecular and cellular biology
Keywords	Principal Investigator O-GlcNAc / EOGT / Notch / NOTCH / O-結合型糖鎖 / 糖鎖修飾 / Notch受容体 / O型糖鎖 / マウス / ジストログリカン … More / Dystroglycan / 糖鎖 / 糖転移酵素 / コラーゲン / POGLUT1 / POFUT1 / フォールディング / 輸送 / 筋線維 / 骨格筋 / 筋繊維 / 細胞接着 / O-GlcNAcc / Eogt / Notch1 / O-glycan / 血管内皮 / vascular permeability / BRB / BBB / 血液脳関門 / 血管integrity / 血管形成 / トランスポーター / GlcNAc / 小胞体 / zebrafish / CTD110.6 / GTDC2 / α-Dystroglycan / glycosylation / EGF / O-GlcNAc転移酵素 / 発生・分化 / タンパク質 / シグナル伝達 / 0-フコース転移酵素 / 0-結合型糖鎖 / O-フコース転移酵素 … More Except Principal Investigator 糖鎖 / グライコプロテオミクス / POGLUT1 / 筋衛星細胞 / レポーターマウス / Notch シグナル / O-グルコース糖鎖 / 質量分析 / サテライト細胞 / Notchシグナル / 糖転移酵素 / O-グルコース糖鎖修飾 / 環境 / 食品 / 感染症 / ウイルス Less

糖転移酵素群によるNOTCHタンパク質の分泌・分解の仕分け機構の解明Principal Investigator
- Principal Investigator
  
  岡島徹也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nagoya University
加齢に伴う運動能力低下におけるNotch1上の細胞外O-GlcNAc機能の解明Principal Investigator
- Principal Investigator
  
  岡島徹也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nagoya University
Regulation of Notch signaling in muscle satellite cells by O-glucose glycosylation
- Principal Investigator
  
  Takeuchi Hideyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  University of Shizuoka
  Nagoya University
Integrated analysis of atypical glycosylation as a basis for precise regulation of Notch signaling in the vascular endotheliumPrincipal Investigator
- Principal Investigator
  
  Okajima Tetsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nagoya University
Roles of Notch signaling and hexosamine pathway on regulation of blood brain barrierPrincipal Investigator
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
細胞外O-GlcNAc修飾のNotchシグナルと血管形成における役割（国際共同研究強化）Principal Investigator
- Principal Investigator
  
  岡島徹也
- Project Period (FY)
  2015
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
小胞体GlcNAc修飾の神経組織での役割Principal Investigator
- Principal Investigator
  
  岡島徹也
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Roles of extracellular O-GlcNAc on Notch signaling and vascular developmentPrincipal Investigator
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Functional analysis of orphan glycolsyltransferases associated with congenital muscular dystrophies using model organismsPrincipal Investigator
- Principal Investigator
  
  Okajima Tetsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
神経組織の機能発現に関与する新規ドメイン特異糖鎖の解析Principal Investigator
- Principal Investigator
  
  岡島徹也
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Biological and biochemical analyses of Drosophilamutants lacking a novel O-GlcNAc modificationPrincipal Investigator
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Identification of a novel post-translational modification of epidermal growth factor domains and mechanistic analysis of the modificationPrincipal Investigator
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
腸上皮細胞および二枚貝中腸腺細胞へのノロウイルスVLPの結合と細胞応答
- Principal Investigator
  
  松田幹
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Nagoya University
Regulatory mechanisms for the structure and function of Notch receptors by Ofut1Principal Investigator
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University

[Book] 糖鎖の新機能開発・応用ハンドブック―創薬・医療から食品開発まで2015
- Author(s)
  谷口直之、顧　建国、中田　博、岡島徹也、古川鋼一、小川光貴、秋元義弘、木下タロウ、北川裕之、菅原一幸、山本一夫、山田修平、宮城妙子　北島　健、木全弘治、松野健治、岡　昌吾、深瀬浩一、門松健治、川島博人、鈴木　匡、加藤晃一　宮本寛子ら
- Total Pages
  678
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-15K15064
[Book] 糖鎖の新機能開発・応用ハンドブック―創薬・医療から食品開発まで2015
- Author(s)
  谷口直之、顧　建国、中田　博、岡島徹也、古川鋼一、小川光貴、秋元義弘、木下タロウ、北川裕之、菅原一幸、山本一夫、山田修平、宮城妙子　北島　健、木全弘治、松野健治、岡　昌吾、深瀬浩一、門松健治、川島博人、鈴木　匡、加藤晃一　宮本寛子ら
- Total Pages
  678
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PUBLICLY-26110709
[Book] 糖鎖の新機能開発・応用ハンドブック―創薬・医療から食品開発まで2015
- Author(s)
  谷口直之、顧　建国、中田　博、岡島徹也、古川鋼一、小川光貴、秋元義弘、木下タロウ、北川裕之、菅原一幸、山本一夫、山田修平、宮城妙子　北島　健、木全弘治、松野健治、岡　昌吾、深瀬浩一、門松健治、川島博人、鈴木　匡、加藤晃一　宮本寛子ら
- Total Pages
  678
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-26291020
[Book] ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5,6 (ST6GALNAC5,6) in “Handbook of Glycosyltransferases and Related Genes” (Eds. Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T.)2013
- Author(s)
  Furukawa K, Okajima, T. Tsuchida A, and Furukawa, K.
- Total Pages
  1707
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-24110507
[Book] ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5,6 (ST6GALNAC5,6) in “Handbook of Glycosyltransferases and Related Genes” (Eds. Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T.)2013
- Author(s)
  Furukawa K, Okajima, T. Tsuchida A, and Furukawa, K.
- Total Pages
  1707
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670140
[Book] ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (ST3GAL6). in “Handbook of Glycosyltransferases and Related Genes” (Eds. Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T.)2013
- Author(s)
  Okajima, T., and Furukawa, K.
- Total Pages
  1706
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670140
[Book] ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (ST3GAL6). in “Handbook of Glycosyltransferases and Related Genes” (Eds. Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T.)2013
- Author(s)
  Okajima, T., and Furukawa, K.
- Total Pages
  1707
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-24110507
[Journal Article] Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans2024
- Author(s)
  Tsukamoto Yohei、Tsukamoto Natsumi、Saiki Wataru、Tashima Yuko、Furukawa Jun-ichi、Kizuka Yasuhiko、Narimatsu Yoshiki、Clausen Henrik、Takeuchi Hideyuki、Okajima Tetsuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 703 Pages: 149610-149610
- DOI
  10.1016/j.bbrc.2024.149610
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ1062, KAKENHI-PROJECT-23K24077, KAKENHI-PROJECT-23K24759
[Journal Article] Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl12024
- Author(s)
  Kondo Yuji、Li Yuxin、Okajima Tetsuya
- Journal Title
  
  Molecules
  
  Volume: 29 Issue: 5 Pages: 1031-1031
- DOI
  10.3390/molecules29051031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06124, KAKENHI-PROJECT-23K24077
[Journal Article] Inhibitory machinery for the functional dystroglycan glycosylation2023
- Author(s)
  Kondo Yuji、Okajima Tetsuya
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 5 Pages: 333-335
- DOI
  10.1093/jb/mvad003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-22K06124, KAKENHI-PROJECT-23K24077
[Journal Article] Evidence that only EWS among the FET proteins acquires a low partitioning property for the hyperosmotic stress response by O-GlcNAc glycosylation on its low-complexity domain2023
- Author(s)
  Kakuo Manami、Horii Takeshi、Tonomura Naoto、Sato Runa、Ogawa Mitsutaka、Okajima Tetsuya、Kamemura Kazuo
- Journal Title
  
  Experimental Cell Research
  
  Volume: 424 Issue: 1 Pages: 113504-113504
- DOI
  10.1016/j.yexcr.2023.113504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-23K24077
[Journal Article] Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH12022
- Author(s)
  Tsukamoto Yohei、Ogawa Mitsutaka、Yogi Kentarou、Tashima Yuko、Takeuchi Hideyuki、Okajima Tetsuya
- Journal Title
  
  Glycobiology
  
  Volume: N/A Issue: 7 Pages: 616-628
- DOI
  10.1093/glycob/cwac015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-23K24077
[Journal Article] Significant Roles of Notch O-Glycosylation in Cancer2022
- Author(s)
  Wang Weiwei、Okajima Tetsuya、Takeuchi Hideyuki
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 6 Pages: 1783-1783
- DOI
  10.3390/molecules27061783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-23K24077
[Journal Article] Eogt-catalyzed <i>O</i>-GlcNAcylation2022
- Author(s)
  Lo Pei-Wen、Okajima Tetsuya
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 34 Issue: 197 Pages: E1-E6
- DOI
  10.4052/tigg.2033.1E
- NAID
  130008144174
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2022-01-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20F20410
[Journal Article] Secretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation2022
- Author(s)
  Zhang Ailing、Tsukamoto Yohei、Takeuchi Hideyuki、Nishiwaki Kimitoshi、Tashima Yuko、Okajima Tetsuya
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 656 Pages: 114881-114881
- DOI
  10.1016/j.ab.2022.114881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-23K24077
[Journal Article] Contribution of glucosylceramide synthase to the proliferation of mouse osteoblasts2021
- Author(s)
  Mishima, Y., Hamamura, K., Kato, H., Furukawa, K., Tashima, Y., Okajima, T., Kondo, H., Sato, T., Miyazawa, K., Goto, S., Togari, A.
- Journal Title
  
  In Vivo
  
  Volume: 35 Issue: 6 Pages: 3111-3123
- DOI
  10.21873/invivo.12606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02628, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-20K09899, KAKENHI-PROJECT-19K22518
[Journal Article] Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins.2021
- Author(s)
  Yesmin, F., Bhuiyan, R.H., Ohmi, Y., Yamamoto, S., Kaneko, K., Ohkawa, Y., Zhang, P., Hamamura, K., Cheung, N-K.V., Kotani, N., Honke, K., Okajima, T., Kambe, M., Tajima, O., Furukawa, K., Furukawa, K.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23 Issue: 1 Pages: 423-442
- DOI
  10.3390/ijms23010423
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-18H02628, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-20K07629, KAKENHI-PROJECT-20K09899, KAKENHI-PROJECT-21K06828, KAKENHI-PROJECT-21K15493, KAKENHI-PROJECT-19K22518
[Journal Article] Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers2021
- Author(s)
  Barua Rashu、Mizuno Kazuyuki、Tashima Yuko、Ogawa Mitsutaka、Takeuchi Hideyuki、Taguchi Ayumu、Okajima Tetsuya
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 4 Pages: 882-882
- DOI
  10.3390/molecules26040882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-19KK0195
[Journal Article] Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions2021
- Author(s)
  Saiki Wataru、Ma Chenyu、Okajima Tetsuya、Takeuchi Hideyuki
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 2 Pages: 309-309
- DOI
  10.3390/biom11020309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19H03176
[Journal Article] Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine2020
- Author(s)
  Hashiguchi Hiroki、Tsukamoto Yohei、Ogawa Mitsutaka、Tashima Yuko、Takeuchi Hideyuki、Nakamura Masanao、Kawashima Hiroki、Fujishiro Mitsuhiro、Okajima Tetsuya
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 695 Pages: 108653-108653
- DOI
  10.1016/j.abb.2020.108653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07801, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03416
[Journal Article] Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia2020
- Author(s)
  Yesmin F, Bhuiyan RH, Ohmi Y, Ohkawa Y, Tajima O, Okajima T, Furukawa K, Furukawa K.
- Journal Title
  
  J Biochem.
  
  Volume: 168 Issue: 2 Pages: 103-112
- DOI
  10.1093/jb/mvaa041
- NAID
  40022308727
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06925, KAKENHI-PROJECT-20K07629, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-18H02628, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-19K07393
[Journal Article] Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking2020
- Author(s)
  Urata Yusuke、Saiki Wataru、Tsukamoto Yohei、Sago Hiroaki、Hibi Hideharu、Okajima Tetsuya、Takeuchi Hideyuki
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 5 Pages: 1220-1220
- DOI
  10.3390/cells9051220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-19H03851
[Journal Article] N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization2020
- Author(s)
  Alam Sayad Md. Didarul、Tsukamoto Yohei、Ogawa Mitsutaka、Senoo Yuya、Ikeda Kazutaka、Tashima Yuko、Takeuchi Hideyuki、Okajima Tetsuya
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 25 Pages: 8560-8574
- DOI
  10.1074/jbc.ra119.012280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176
[Journal Article] Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking2020
- Author(s)
  Ogawa M, Tashima Y, Sakaguchi Y, Takeuchi H and Okajima T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 526 Issue: 1 Pages: 184-190
- DOI
  10.1016/j.bbrc.2020.03.066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-19H03416
[Journal Article] Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs2020
- Author(s)
  Ma Chenyu、Takeuchi Hideyuki、Hao Huilin、Yonekawa Chizuko、Nakajima Kazuki、Nagae Masamichi、Okajima Tetsuya、Haltiwanger Robert S.、Kizuka Yasuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 17 Pages: 6007-6007
- DOI
  10.3390/ijms21176007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-20H03207
[Journal Article] Structure and function of extracellular O-GlcNAc.2019
- Author(s)
  Ogawa M, Okajima T.
- Journal Title
  
  Curr Opin Struct Biol.
  
  Volume: 56 Pages: 72-77
- DOI
  10.1016/j.sbi.2018.12.002
- NAID
  120006771426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03416
[Journal Article] O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals2017
- Author(s)
  *Shogo Sawaguchi, *Shweta Varshney, *Mitsutaka Ogawa, Yuta Sakaidani, Hirokazu Yagi, Kyosuke Takeshita, Toyoaki Murohara, Koichi Kato, Subha Sundaram , Pamela Stanley and Tetsuya Okajima. (*equal contribution)
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.24419
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502, KAKENHI-PROJECT-16K15411, KAKENHI-INTERNATIONAL-15K21708, KAKENHI-PROJECT-26291020, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-16J00004, KAKENHI-PROJECT-15K15064
[Journal Article] Expression of B4GALNT1, an essential glycosyltransferase for the synthesis of complex gangliosides, suppresses BACE1 degradation and modulates APP processing2016
- Author(s)
  Yamaguchi T, Yamauchi Y, Furukawa K, Ohmi Y, Ohkawa Y, Zhang Q, Okajima T, Furukawa K
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34505-34505
- DOI
  10.1038/srep34505
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-15K19073, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-15K15080, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26291020
[Journal Article] Intracellular and extracellular O-linked N-acetylglucosamine in the nervous system.2015
- Author(s)
  Ogawa M, Sawaguchi S, Kamemura K, Okajima T.
- Journal Title
  
  Exp Neurol.
  
  Volume: 274 Pages: 166-174
- DOI
  10.1016/j.expneurol.2015.08.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15064, KAKENHI-PROJECT-15K18502, KAKENHI-PUBLICLY-26110709, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-26291020
[Journal Article] Impaired O-linked N-acetylglucosaminylation in the endoplasmic reticulum by mutated EGF domain-specific O-linked N-acetylglucosamine transferase found in Adams-Oliver syndrome2015
- Author(s)
  M.Ogawa, S.Sawaguchi, T.Kawai, D.Nadano, T.Matsuda, H.Yagi, K.Kato, K.Furukawa, and T.Okajima
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 4 Pages: 2137-2149
- DOI
  10.1074/jbc.m114.598821
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-25670141, KAKENHI-PUBLICLY-26110709, KAKENHI-PUBLICLY-26110716, KAKENHI-PROJECT-26291020, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-24390078
[Journal Article] O-fucose monosaccharide of Drosophila Notch has a temperature-sensitive function and cooperates with O-glucose glycan in Notch transport and Notch signaling activation2015
- Author(s)
  Akira Ishio, Takeshi Sasamura, Tomonori Ayukawa, Junpei Kuroda, Hiroyuki O. Ishikawa, Naoki Aoyama, Kenjiroo Matsumoto, Takuma Gushiken, Tetsuya Okajima, Tomoko Yamakawa and Kenji Matsuno2
- Journal Title
  
  Jounal of Biochemistry
  
  Volume: 290 Issue: 1 Pages: 505-519
- DOI
  10.1074/jbc.m114.616847
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J06669, KAKENHI-PROJECT-24370091, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-25840031, KAKENHI-PUBLICLY-26110709, KAKENHI-PROJECT-26291020, KAKENHI-PROJECT-26440113, KAKENHI-PLANNED-15H05863
[Journal Article] N-acetylglucosamine modification in the lumen of the endoplasmic reticulum.2015
- Author(s)
  Ogawa M, Sawaguchi S, Furukawa K, Okajima T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1850 Issue: 6 Pages: 1319-1324
- DOI
  10.1016/j.bbagen.2015.03.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15064, KAKENHI-PROJECT-15K18502, KAKENHI-PUBLICLY-26110709, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-26291020
[Journal Article] Ganglioside GD3 enhances invasiveness via Yes activation by forming a complex of GD3/PDGFRα/Yes in gliomas2015
- Author(s)
  Yuki Ohkawa, Hiroyuki Momota, Akira Kato, Noboru Hashimoto, Yuhsuke Tsuda, Norihiro Kotani, Koichi Honke, Akio Suzumura, Keiko Furukawa, Yuhsuke Ohmi, Atsushi Natsume, Toshihiko Wakabayashi and *Furukawa K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 32 Pages: 16043-16058
- DOI
  10.1074/jbc.m115.708834
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-15H04696, KAKENHI-PROJECT-16J00004, KAKENHI-PROJECT-15K18502, KAKENHI-PROJECT-15K19073, KAKENHI-PROJECT-16K08591, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K15080, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26291020
[Journal Article] Extracellular O-linked beta-N-acetylglucosamine: Its biology and relationship to human disease.2014
- Author(s)
  Ogawa M, Furukawa K, Okajima T.
- Journal Title
  
  World J Biol Chem
  
  Volume: 5 Pages: 224-230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670140
[Journal Article] Extracellular O-linked beta-N-acetylglucosamine: Its biology and relationship to human disease.2014
- Author(s)
  Ogawa M, Furukawa K, Okajima T.
- Journal Title
  
  World J Biol Chem
  
  Volume: 5 Pages: 224-230
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26110709
[Journal Article] Extracellular O-linked beta-N-acetylglucosamine: Its biology and relationship to human disease.2014
- Author(s)
  Ogawa M, Furukawa K, Okajima T.
- Journal Title
  
  World J Biol Chem
  
  Volume: 5 Pages: 224-230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26291020
[Journal Article] Dephosphorylation reduces passage of ovalbumin antigen through intestinal epithelial Caco-2 cell monolayers.2013
- Author(s)
  Matsubara, T., Akiyama, Y., Oshima, K., Okajima, T., Nadano, D., and Matsuda, T.
- Journal Title
  
  J Biochem
  
  Volume: 153 Issue: 4 Pages: 347-354
- DOI
  10.1093/jb/mvs154
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110507, KAKENHI-PROJECT-25670140
[Journal Article] Allergenic potential of rice pollen proteins: expression, immuno-cross reactivity and IgE-binding2013
- Author(s)
  Hirano K et al
- Journal Title
  
  J Biochem
  
  Volume: 154 Issue: 2 Pages: 195-205
- DOI
  10.1093/jb/mvt044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658110, KAKENHI-PUBLICLY-24110507, KAKENHI-PROJECT-25660101, KAKENHI-PROJECT-25670140
[Journal Article] GTDC2 modifies O-mannosylated α-dystroglycan in the endoplasmic reticulum to generate N-acetyl-glucosamine epitopes reactive with CTD110.6 antibody.2013
- Author(s)
  Ogawa M, Nakamura N, Nakayama Y, Kurosaka A, Manya H, Kanagawa M, Endo T, Furukawa K, Okajim T
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 440 Issue: 1 Pages: 88-93
- DOI
  10.1016/j.bbrc.2013.09.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PUBLICLY-24110507, KAKENHI-PUBLICLY-24110508, KAKENHI-PUBLICLY-24110516, KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-24687017, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25670140
[Journal Article] Trimeric Tn antigen on Syndecan-1 binds to integrins and enhances cancer metastasis via dynamic changes of membrane microdomains.2013
- Author(s)
  Matsumoto Y, Zhang Q, Akita K, Nakada H, Hamamura K, Tsuchida A, Okajima T, Furukawa K, Urano T, Furukawa K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 33 Pages: 24264-24276
- DOI
  10.1074/jbc.m113.455006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PUBLICLY-24110507, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-25670141
[Journal Article] Post-weaning increases in the milk-fat globule EGF-factor VIII on fat globules in mouse milk and in the uptake of the fat globules by HC11 mammary epithelial cells.2013
- Author(s)
  Nakatani, H., Yasueda, T., Oshima, K., Okajima, T., Nadano, D., Flint, D. J., and Matsuda, T.
- Journal Title
  
  J Biochem
  
  Volume: 153 Issue: 1 Pages: 31-41
- DOI
  10.1093/jb/mvs116
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110507, KAKENHI-PROJECT-25670140
[Journal Article] O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt12012
- Author(s)
  Sakaidani Y, Ichiyanagi N, Saito C, Nomura T, Ito M, Nishio Y, Nadano D, Matsuda T, Furukawa K, Okajima T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 421 Pages: 329-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790328
[Journal Article] pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen2012
- Author(s)
  Matsumoto Y, Zhang Q, Akita K, Nakada H, Hamamura K, Tokuda N, Tsuchida A, Matsubara T, Hori T, Okajima T, Furukawa K, Urano T, Furukawa K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Pages: 7-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790328
[Journal Article] 上皮成長因子ドメインを修飾する特異的O-結合型糖鎖2011
- Author(s)
  岡島徹也
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 813-821
- NAID
  10029737638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790328
[Journal Article] O-Linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions.2011
- Author(s)
  Sakaidani Y, Nomura T, Matsuura A, Ito M, Suzuki E, Murakami K, Nadano D, Matsuda T, Furukawa K, Okajima T
- Journal Title
  
  Nature Commun.
  
  Volume: 13(2) Pages: 583-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790328
[Journal Article] O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions.2011
- Author(s)
  Sakaidani Y, Nomura T, Matsuura A, Ito M, Suzuki E, Murakami K, Nadano D, Matsuda T, Furukawa K, Okajima T
- Journal Title
  
  Nature Commun
  
  Volume: 2 Pages: 583-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790328
[Journal Article] O-GlcNAc modification of the extracellular domain of Notch receptors2010
- Author(s)
  Okajima T
- Journal Title
  
  Trends in Clycoscience and Glycotechnology
  
  Volume: 22 Pages: 247-255
- NAID
  10027893118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] O-GlcNAc modification of the extracellular domain of Notch receptors2010
- Author(s)
  Okajima T, Furukawa K, Sakaidani Y.
- Journal Title
  
  Trends in Glycoscience and Glycotechnology 22
  
  Pages: 247-255
- NAID
  10027893118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] Roles of glycosylation in Notch signaling.2010
- Author(s)
  Stanley, P, Okajima, T.
- Journal Title
  
  Current topics in developmental biology 92
  
  Pages: 131-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] Establishment of a Mammary Stromal Fibroblastic Cell Line for In Vitro Studies in Mice of Mammary Adipocyte Differentiation.Biol.2010
- Author(s)
  Nakatani H, Aoki N, Okajima T, Nadano D, Flint D, Matsuda T.
- Journal Title
  
  Reprod. 82(1)
  
  Pages: 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] O-GlcNAc modification of EGF domains of Notch receptors.2010
- Author(s)
  Sakaidani Y, Furukawa K, Okajima T.
- Journal Title
  
  Methods Enzymol. 480
  
  Pages: 355-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] Periodate-resistant carbohydrate epitopes recognized by IgG and IgE antibodies from some of the immunized mice and patients with allergy.2009
- Author(s)
  Hino S, Matsubara T, Urisu A, Aoki N, Sato C, Okajima T, Nadano D, Matsuda T.
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages: 632-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] Serum and monoclonal IgE antibodies from NC/Nga mice with severe atopic-like dermatitis recognize an autoantigen, histone H32009
- Author(s)
  Matsubara T, Aoki N, Hino H, Okajima T, Nadano D, Matsuda T
- Journal Title
  
  Clin. Exp. Allergy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Glycoconjugate glycosyltransferases.2009
- Author(s)
  Furukawa K, Tsuchida A, Okajima T, Furukawa K.
- Journal Title
  
  Glycoconj.J. 26(8)
  
  Pages: 987-998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790270
[Journal Article] Contributions of chaperone and glycosyltransferase activities of O-fucosvltransferase 1 to Notch signaling2008
- Author(s)
  Okajima T
- Journal Title
  
  BMC biology 6
  
  Pages: 1-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Development and evaluation of transgenic rice seeds accumulating a type II-collagen tolerogenic peptide2008
- Author(s)
  Hashizume F, Hino S, Kakehashi M, Okajima T , Nadano D, Aoki N, and Matsuda T
- Journal Title
  
  Transgenic Research 17
  
  Pages: 1117-1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch sianalina2008
- Author(s)
  Okajima T, et.al.
- Journal Title
  
  BMC biology 6
  
  Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Biological functions of glycosyltransferase genes involved in O-fucose glycan synthesis2008
- Author(s)
  Okajima T
- Journal Title
  
  J. Biochem (In press)
- NAID
  10024910612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling2008
- Author(s)
  Okajima T, Reddy B, Matsuda T and Irvine KD
- Journal Title
  
  BMC biology 6
  
  Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Absorption, Migration and Kinetics in Peripheral Blood of Orally Administered Ovalbumin in a Mouse Model2008
- Author(s)
  Matsubara T, Aoki N, Honjoh T, Mizumachi K, Kurisaki JI, Okajima T, Nadano D, Matsuda T
- Journal Title
  
  Biosci. Biotechnol. Biochem. 72
  
  Pages: 2555-2565
- NAID
  10027532745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Engineering of a mammalian O-glycosylation pathway in the yeast Saccharomyces cerevisiae: production of O-fucosylated epidermal growth factor domains2008
- Author(s)
  Chigira Y, Oka T, Okajima T and Jigami Y.
- Journal Title
  
  Glycobiology 18
  
  Pages: 303-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Biological functions of glycosyltransferase genes involved in O-fucose glycan synthesis2008
- Author(s)
  Okajima T, Matsuura A, Matsuda T
- Journal Title
  
  J. Biochem. 144
  
  Pages: 1-6
- NAID
  10024910612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] 糖転移酵素のNotch受容体フォールディングにおける役割2008
- Author(s)
  松浦愛子・松田幹・岡島徹也
- Journal Title
  
  蛋白質核酸酵素 53
  
  Pages: 1480-1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] O-linked GlcNAc is present on the extracellular domain of Notch receptors2008
- Author(s)
  Matsuura A, Ito M, Sakaidani Y, Kondo T, Murakami K, Furukawa K, Nadano D, Matsuda T, and Okajima T
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 35486-35495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Glycoconjugate glycosyltransferases2008
- Author(s)
  Furukawa K, Tsuchida A, Okajima T, Furukawa K
- Journal Title
  
  Glycoconj. J. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Suppressive expression of the glutelin A1-collagen peptide fusion gene in hybrid rice lines with the mutant line, Low Glutelin Content-1 (LGC-1)2008
- Author(s)
  Hashizume F, Hino S, Okajima T, Nadano D, Aoki N and Matsuda T
- Journal Title
  
  Plant Biotechnol. 25
  
  Pages: 465-471
- NAID
  10021914665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Biological functions of glycosyltransferase genes involved in O-fucoseglycan synthesis2008
- Author(s)
  Okajima T, et.al.
- Journal Title
  
  J. Biochem. 144
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Bystin in human cancer cells. Intracellular localization and function in ribosome biogenesis2007
- Author(s)
  Miyoshi M, Okajima T, Matsuda T, Fukuda MN, Nadano D
- Journal Title
  
  Biochem. J 404
  
  Pages: 373-381
- NAID
  120006406625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Association of chicken zona pellucida glycoprotein (ZP) B1 with ZPC induces formation of ZPB1-ZPC fibrous aggregates containing disulfide-bridged ZPB1 dimer2007
- Author(s)
  Okumura H, Okajima T, Nadano D, Matsuda T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 364
  
  Pages: 682-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] EGFドメインに見いだされる新型糖鎖と生体機能制御2006
- Author(s)
  岡島徹也
- Journal Title
  
  化学と生物 44
  
  Pages: 802-804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Roles of O-fucosyltransferase I and O-linked fucose in notch receptor function2006
- Author(s)
  Okajima T, Matsuda T
- Journal Title
  
  Methods Enzymol. 417
  
  Pages: 111-126
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] Roles of fucosyltransferase and fucose in Notch signaling2006
- Author(s)
  Okajima T, Matsuda T
- Journal Title
  
  Methods Enzymol. 417
  
  Pages: 111-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689011
[Journal Article] EGFドナインに見いだされる新型糖鎖と生体機能制御2006
- Author(s)
  岡島徹也
- Journal Title
  
  化学と生物 44, 12
  
  Pages: 802-804
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] The structure and function of "extracellular" O-GlcNAc modification in mammals2023
- Author(s)
  Tetsuya Okajima, Yuji Kondo, Yuko Tashima
- Organizer
  TAIWAN Glyco26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] Eogtは動脈内皮細胞特異的糖転移酵素である2023
- Author(s)
  近藤裕史、河合香里、岡島徹也
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] Eogtは動脈内皮細胞特異的糖転移酵素である2023
- Author(s)
  近藤裕史、河合香里、岡島徹也
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] 小胞体での品質管理におけるNOTCH受容体のO型糖鎖修飾の役割2023
- Author(s)
  田嶌優子, 大橋憲太郎, 塚本庸平, 岡島徹也
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] 小胞体でのフォールディング管理におけるNOTCH受容体のO型糖鎖修飾の役割2023
- Author(s)
  田嶌優子、大橋憲太郎、塚本庸平、岡島徹也
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] Roles of POFUT1 and POGLUT1 for the effective transport of DLK1 to the cell surface2022
- Author(s)
  Yuko Tashima, Wakako Goto, Yohei Tsukamoto, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] 細胞外O-GlcNAc転移酵素の組織発見分布解析と生体内における機能探索2022
- Author(s)
  近藤裕史、岡島徹也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] Oーfucose修飾とO-glucose修飾はDLK1の効率的な輸送に大事である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Roles of POFUT1 and POGLUT1 for the effective transport of DLK1 to the cell surface2022
- Author(s)
  Yuko Tashima, Wakako Goto, Yohei Tsukamoto, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] O-fucoseとO-glucose修飾はDLK1の効率的な輸送に重要である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] Oーfucose修飾とO-glucose修飾はDLK1の効率的な輸送に大事である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] 3’-Sialyllactose on Notch: Notch1 functions as a scaffold of O-linked, 3’-sialyllactosylated glycans2022
- Author(s)
  Yohei Tsukamto, Kazuhiro Aoki, Yoshiki Narimatsu, Yusuke Urata, Wataru Saiki, Michael Tiemeyer, Henrik Clausen, Yuki Kurebayashi, Akira Minami, Tadanobu Takahashi, Tetsuya Okajima, and Hideyuki Takeuchi
- Organizer
  Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24077
[Presentation] 細胞外O-GlcNAc転移酵素の組織発見分布解析と生体内における機能探索2022
- Author(s)
  近藤裕史、岡島徹也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] 3’-Sialyllactose on Notch: Notch1 functions as a scaffold of O-linked, 3’-sialyllactosylated glycans2022
- Author(s)
  Yohei Tsukamto, Kazuhiro Aoki, Yoshiki Narimatsu, Yusuke Urata, Wataru Saiki, Michael Tiemeyer, Henrik Clausen, Yuki Kurebayashi, Akira Minami, Tadanobu Takahashi, Tetsuya Okajima, and Hideyuki Takeuchi
- Organizer
  Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Roles of O-fucose and O-glucose for the effective transport of DLK1 to the cell surface2022
- Author(s)
  Yuko Tashima, Wakako Goto, Yohei Tsukamoto, Natsumi Tsukamoto, Shiori Go, Hiroyuki Kaji, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  2023 Glycobiology Conference GRC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] O-fucoseとO-glucose修飾はDLK1の効率的な輸送に重要である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] 細胞外 O-GlcNAc 修飾は EGF ドメインの安定性と Notch1 のトラフィッキングに寄与する2020
- Author(s)
  小川光貴、田嶌優子、坂口大和、竹内英之、岡島徹也
- Organizer
  第 93 回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03176
[Presentation] 血液凝固第 XII 因子の活性化抑制における糖鎖修飾の役割2020
- Author(s)
  中村澄香、小川光貴、竹内英之、岡島徹也、有森貴夫、高木淳一、相川京子
- Organizer
  第 93 回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03176
[Presentation] Protein delta homolog-1 の O-glycan による小胞体から細胞膜への輸送制御の解析2020
- Author(s)
  田嶌優子、後藤和佳子、妹尾勇弥、塚本庸平、池田和貴、小川光貴、竹内英之、岡島徹也
- Organizer
  第39回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] 細胞外O-GlcNAc修飾はEGFドメインの安定性とNotch1のトラフィッキングへの寄与する2020
- Author(s)
  小川光貴, 田嶌優子, 坂口大和, 竹内英之, 岡島徹也
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Significance of structurally diverse elongation of O-glucose glycans on Notch1 and Notch22019
- Author(s)
  Takeuchi H, Urata Y, Tsukamoto Y, Saiki W, Senoo Y, Ma C, Wang WW, Aoki K, Tiemeyer M, and Okajima T
- Organizer
  Annual Meeting of Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03176
[Presentation] Notch受容体糖鎖による生体機能の精密制御機構の理解を目指したグライコプロテオミクス研究2019
- Author(s)
  岡島徹也, 小川光貴, 竹内英之
- Organizer
  第9回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] The interplay of distinct glycosylations on epidermal growth factor (EGF)-like repeats2019
- Author(s)
  Okajima T
- Organizer
  11th Asian Connunity of Glycosciences and Glucotechnology (ACGG) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Notch1 受容体上のO-GlcNAc glycan は細胞外環境に応答する2019
- Author(s)
  与儀賢太朗, 小川光貴, 妹尾勇弥, 池田和貴, 竹内英之, 岡島徹也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Identification of fucose-containing novel O-GlcNAc glycan2019
- Author(s)
  Mitsutaka Ogawa, Kentarou Yogi, Yuya Senoo, Kazutaka Ikeda, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Notch 受容体上の O- 結合型糖鎖修飾の質量分析計を用いた網羅的解析2019
- Author(s)
  塚本庸平, 妹尾勇弥, 浦田悠輔, 齊木颯, 小川光貴, 池田和貴, 竹内英之, 岡島徹也
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] 新しい細胞外 O-GlcNAc修飾の分子機能2017
- Author(s)
  小川光貴、古川鋼一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 細胞外O-GlcNAcの修飾に関わるEOGT変異マウスの表現型解析2017
- Author(s)
  澤口翔伍、小川光貴、矢木宏和、加藤晃一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] 脳血管内皮細胞分化におけるNotch受容体O-GlcNAc修飾の役割2017
- Author(s)
  平泉光佑、澤口翔伍、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] 新しい細胞外 O-GlcNAc修飾の分子機能2017
- Author(s)
  小川光貴、古川鋼一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] 細胞外O-GlcNAcの修飾に関わるEOGT変異マウスの表現型解析2017
- Author(s)
  澤口翔伍、小川光貴、矢木宏和、加藤晃一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 脳血管内皮細胞分化におけるNotch受容体O-GlcNAc修飾の役割2017
- Author(s)
  平泉光佑、澤口翔伍、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] ガングリオシドGD3によるグリオーマの腫瘍微小環境の制御機構2017
- Author(s)
  張璞、大川裕樹、加藤彰、小峯起、百田洋之、Robiul Bhuiyan、大海雄介、古川圭子、若林俊彦、岡島徹也、山中宏二、古川鋼一
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] ガングリオシドGD3によるグリオーマの腫瘍微小環境の制御機構2017
- Author(s)
  張璞、大川裕樹、加藤彰、小峯起、百田洋之、Robiul Bhuiyan、大海雄介、古川圭子、若林俊彦、岡島徹也、山中宏二、古川鋼一
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Extracellular O-GlcNAc regulates Delta-like 4 mediated Notch signaling and vascular development in mammals2016
- Author(s)
  澤口翔伍, 小川光貴, 矢木宏和, 加藤晃一, 岡島徹也
- Organizer
  第89回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] 細胞外O-GlcNacが制御するNotch受容体リガンド相互作用2016
- Author(s)
  岡島徹也, 小川光貴, 澤口翔伍
- Organizer
  日本糖質学会年会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Extracellular O-GlcNAc regulates Delta-like 4 mediated Notch signaling and vascular development in mammals2016
- Author(s)
  澤口翔伍, 小川光貴, 矢木宏和, 加藤晃一, 岡島徹也
- Organizer
  日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Analysis of the biological roles of extracellular O-GlcNAc using EOGT-deficient mice2015
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  Society for Glycobiology 2015 Annual Meeting
- Place of Presentation
  サンフランシスコ（アメリカ）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Phenotypic analysis of mice mutant for EOGT involved in extracellular O-GlcNAc modification.2015
- Author(s)
  Shogo Sawaguchi, Mitsutaka Ogawa, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, and Tetsuya Okajima
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Analysis of the biological roles of extracellular O-GlcNAc using EOGT-deficient mice2015
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  Society for Glycobiology 2015 Annual Meeting
- Place of Presentation
  サンフランシスコ（アメリカ）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 細胞外0-GlcNAc：生物学と疾患との関連2015
- Author(s)
  岡島徹也、澤口翔伍、古川鋼一、小川光貴
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood retinal barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  生化学会中部支部例会シンポジウム
- Place of Presentation
  信州大学（長野県松本市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Extracellular O-GlcNAc modification regulates Notch signaling and blood-retina barrier maintenance2015
- Author(s)
  小川光貴、澤口翔伍、Bieniasz-krzywiec Pawl, 矢木宏和、加藤晃一、臼倉治郎、古川鋼一、岡島徹也
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood retinal barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  生化学会中部支部例会シンポジウム
- Place of Presentation
  信州大学（長野県松本市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] 細胞外0-GlcNAc：生物学と疾患との関連2015
- Author(s)
  岡島徹也、澤口翔伍、古川鋼一、小川光貴
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Analysis of the biological roles of extracellular O-GlcNAc using EOGT-deficient mice2015
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  Society for Glycobiology 2015 Annual Meeting
- Place of Presentation
  サンフランシスコ（アメリカ）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood brain barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Extracellular O-GlcNAc modification regulates Notch signaling and blood0retina barrier maintenance2015
- Author(s)
  小川光貴、澤口翔伍、Bieniasz-krzywiec Pawl, 矢木宏和、加藤晃一、臼倉治郎、古川鋼一、岡島徹也
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Phenotypic analysis of mice mutant for EOGT involved in extracellular O-GlcNAc modification.2015
- Author(s)
  Shogo Sawaguchi, Mitsutaka Ogawa, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, and Tetsuya Okajima
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood brain barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Extracellular O-GlcNAc modification regulates Notch signaling and blood-retina barrier maintenance2015
- Author(s)
  小川光貴、澤口翔伍、Bieniasz-krzywiec Pawl, 矢木宏和、加藤晃一、臼倉治郎、古川鋼一、岡島徹也
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 細胞外0-GlcNAc：生物学と疾患との関連2015
- Author(s)
  岡島徹也、澤口翔伍、古川鋼一、小川光貴
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood retinal barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  生化学会中部支部例会シンポジウム
- Place of Presentation
  信州大学（長野県松本市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood brain barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Phenotypic analysis of mice mutant for EOGT involved in extracellular O-GlcNAc modification.2015
- Author(s)
  Shogo Sawaguchi, Mitsutaka Ogawa, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, and Tetsuya Okajima
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Biochemical and functional analysis of EOGT mutation associated with Adams-Oliver syndrome2014
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Takami Kawai, Yuta Sakaidani, Hirokazu Yagi, Koichi Kato, Koichi Furukawa, Tetsuya Okajima
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台（淡路市）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] Role of extracellular O-GlcNAc in Notch signaling, retinal vascular development, and blood brain barrier function2014
- Author(s)
  Ogawa M, Bieniasz-Krzywiec P, Yagi H, Kato K, Usukura J. Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting - Satellite II: Glycans in Neuroscience
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Roles of O-glycosylation in Notch signaling pathway2014
- Author(s)
  Tetsuya Okajima
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台（淡路市）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] Role of extracellular O-GlcNAc in Notch signaling, retinal vascular development, and blood brain barrier function2014
- Author(s)
  Ogawa M, Bieniasz-Krzywiec P, Yagi H, Kato K, Usukura J. Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting - Satellite II: Glycans in Neuroscience
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] Biochemical and functional analysis of EOGT mutation associated with Adams-Oliver syndrome.2014
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Takami Kawai, Yuta Sakaidani, Hirokazu Yagi, Koichi Kato, Koichi Furukawa, Tetsuya Okajima
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台（淡路市）
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] Role of extracellular O-GlcNAc in Notch signaling, retinal vascular development, and blood brain barrier function2014
- Author(s)
  Ogawa M, Bieniasz-Krzywiec P, Yagi H, Kato K, Usukura J. Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting - Satellite II: Glycans in Neuroscience
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] Roles of O-glycosylation in Notch signaling pathway. International Symposium on Glyco-Neuroscience2014
- Author(s)
  Tetsuya Okajima
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台（淡路市）
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] アダムズ-オリバー症候群に関わるEogt遺伝子変異の分子機構解析2013
- Author(s)
  小川光貴、河合崇生、堺谷祐太、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪交流センター（大阪市）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] EOGTの酵素化学的性質とアダムズ―オリバー症候群の関連性2013
- Author(s)
  小川光貴、堺谷祐太、河合崇生、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] アダムズ-オリバー症候群に関わるEogt遺伝子変異の分子機構解析2013
- Author(s)
  小川光貴、河合崇生、堺谷祐太、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] OGT の酵素化学的性質とアダムズ- オリバー症候群の関連性2013
- Author(s)
  小川光貴、河合崇生、堺谷祐太、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] EOGTの酵素化学的性質とアダムズ―オリバー症候群の関連性2013
- Author(s)
  小川光貴、堺谷祐太、河合崇生、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] EOGT の酵素化学的性質とアダムズ- オリバー症候群の関連性2013
- Author(s)
  小川光貴、河合崇生、堺谷祐太、矢木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] O-GlcNAc modification of EGF-like domains by a novel O-GlcNAc transferences, EGOT2012
- Author(s)
  Tetsuya Okajima
- Organizer
  Commemorative Symposium on the 20th Anniversary of the Mizutani Foundation for Glycoscience
- Place of Presentation
  東京コンファレンスセンター（品川）
- Invited
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] 新規O-GlcNAc転移酵素遺伝子Eogt のクローニングと機能解析2012
- Author(s)
  岡島徹也
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール（鹿児島）
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] O-GlcNAc modification of EGF-like domains by a novel O-GlcNAc transferences2012
- Author(s)
  Tetsuya Okajima
- Organizer
  EGOT. Commemorative Symposium on the 20thAnniversary of the Mizutani Foundation for Glycoscience
- Place of Presentation
  東京
- Year and Date
  2012-11-28
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] 新規O-GlcNAc転移酵素遺伝子Eogt のクローニングと機能解析2012
- Author(s)
  岡島徹也、中倉真之、堺谷祐太、大海雄介、近藤裕史、西尾洋介、増田達也、八木宏和、加藤晃一、古川鋼一
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] 新規O-GlcNAc転移酵素遺伝子Eogt のクローニングと機能解析2012
- Author(s)
  岡島徹也
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール（鹿児島）
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] O-GlcNAc modification of EGF-like domains by a novel O-GlcNAc transferences, EGOT2012
- Author(s)
  Tetsuya Okajima
- Organizer
  Commemorative Symposium on the 20th Anniversary of the Mizutani Foundation for Glycoscience
- Place of Presentation
  東京コンファレンスセンター（品川）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24110507
[Presentation] 新規O-GlcNAc転移酵素遺伝子の基質認識と生理学的役割2012
- Author(s)
  堺谷祐太、野村朋子、松浦愛子、伊藤麻紀子、鈴木えみ子、村上耕介、灘野大太、松田幹、古川鋼一、岡島徹也
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] trimeric Tn 抗原による癌転移能亢進の分子メカニズムの解明2012
- Author(s)
  松本康之、章青、浜村和紀、秋田薫、中田博、土田明子、岡島徹也、古川圭子、浦野健、古川鋼一
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] マウスO-GlcNAc転移酵素遺伝子Eogt のクローニングと遺伝子欠損マウスの作製2012
- Author(s)
  中倉真之、堺谷祐太、大海雄介、近藤裕史、西尾洋介、増田達也、八木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  糖鎖科学中部拠点第10回「若手の力」フォーラム
- Place of Presentation
  静岡
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] マウスO-GlcNAc 転移酵素遺伝子Eogt1 のクローニングと遺伝子欠損マウス2012
- Author(s)
  中倉真之、堺谷祐太、大海雄介、近藤裕史、西尾洋介、増田達也、八木宏和、加藤晃一、古川鋼一、岡島徹也
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  博多
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] O-GlcNAc on extracellular protein domains mediates epithelial cell-matrix interaction2011
- Author(s)
  Yuta Sakaidani, Tomoko Nomura, Aiko Matsuura, Makiko Ito, Emiko Suzuki, Kosuke Murakami, Daita Nadano, Tsukasa Matsuda, Koichi Furukawa, Tetsuya Okajima
- Organizer
  第75回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] Roles of a novel post-translational modification specific for epidermal grouwth factor domains2011
- Author(s)
  Tetsuya Okajima, Masayuki Nakakura, Yuji Kondo, Yuta Sakaidni, Koichi Furukawa
- Organizer
  第34回日本分子生物学会年会(招待講演)
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] Roles of a novel post-translational modification specific for epidermal grouwth factor domains2011
- Author(s)
  Tetsuya Okajima, Masayuki Nakakura, Yuji Kondo, Yuta Sakaidni, Koichi Furukawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] O-GlcNAc on extracellular protein domains mediates epithelial cell-matrix interaction2011
- Author(s)
  堺谷祐太、野村朋子、松浦愛子、伊藤麻紀子、鈴木えみ子、村上耕介、灘野大太、松田幹、古川鋼一、岡島徹也
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23790328
[Presentation] OGT-independent O-GlcNAcylation of EGF domains of Notch receptors2010
- Author(s)
  岡島徹也
- Organizer
  内藤カンファレンス
- Place of Presentation
  湘南国際村
- Data Source
  KAKENHI-PROJECT-21790270
[Presentation] OGT-independent O-GlcNAcylation of EGF domains of Notch receptors.2010
- Author(s)
  岡島徹也
- Organizer
  内藤カンファレンス
- Place of Presentation
  湘南
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-21790270
[Presentation] O-GlcNAc modification on EGF domins of Notch receptors.2009
- Author(s)
  Okajima T.
- Organizer
  Glycobiology meeting 2009
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790270
[Presentation] Notch受容体細胞外ドメインにおけるO-GlcNAc修飾2008
- Author(s)
  伊藤麻紀子、岡島徹也, ら
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] EGFリピートのフォルディングにおけるO-フコース転移酵素1の役割の解明2008
- Author(s)
  堺谷祐太、岡島徹也, ら
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] EGFドメイン特異的O-結合型糖鎖と糖転移酵素遺伝子2008
- Author(s)
  松浦愛子、岡島徹也, ら
- Organizer
  日本糖質学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] O-linked GlcNAc is present on the extracellular domain of Notch receptors2008
- Author(s)
  atsuura A, Okajima T, et al
- Organizer
  Glycobiology meeting
- Place of Presentation
  Fort Worth (USA)
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] ノロウイルス・ウイルス様粒子(VLPs)のヒト腸上皮様Caco-2細胞への結合様式とウシ初乳のVLPs結合抑制効果2008
- Author(s)
  村上耕介, 鈴木さやか, 岡島徹也, 灘野大太, 岡智一郎, 片山和彦, 武田直和, 松田幹
- Organizer
  第81回日本生化学会・第31回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20380184
[Presentation] O-フコース転移酵素1のシャペロン活性と糖転移活性のNotchシグナルにおける寄与2007
- Author(s)
  岡島徹也
- Organizer
  第30回日本分子生物学会/第80回日本生化学会合同学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling2007
- Author(s)
  Okajima T, et al
- Organizer
  Notch研究会
- Place of Presentation
  三島
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling2007
- Author(s)
  Okajima T, et al
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] Genetic and biochemical analysis of O-fucosyltransferase 1 for Notch receptor structure and function2007
- Author(s)
  Okajima T et al
- Organizer
  日本農芸化学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] Requirement of O-fucosyltransferases for Developmental Processes2006
- Author(s)
  Okajima T, et al
- Organizer
  GlycoT 2006
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-18689011
[Presentation] アダムズ-オリバー症候群に関連するEOGT遺伝子変異はER型O-GlcNAc修飾の欠損を引き起こす
- Author(s)
  小川光貴, 河合崇生, 灘野大太, 松田幹, 矢木宏和, 加藤晃一, 古川鋼一, 岡島徹也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] O-GlcNAcylation in the endoplasmic reticulum
- Author(s)
  岡島徹也、小川光貴、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] O-GlcNAcylation in the endoplasmic reticulum
- Author(s)
  岡島徹也、小川光貴、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] アダムズ-オリバー症候群に関連するEOGT遺伝子変異はER型O-GlcNAc修飾の欠損を引き起こす
- Author(s)
  小川光貴, 河合崇生, 灘野大太, 松田幹, 矢木宏和, 加藤晃一, 古川鋼一, 岡島徹也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] O-GlcNAcylation in the endoplasmic reticulum
- Author(s)
  岡島徹也、小川光貴、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場（京都）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Impaired O-GlcNAc Modification in the Endoplasmic Reticulum by Mutated EOGT Assosiated with Adams-Oliver Syndrome.
- Author(s)
  Ogawa M, Kawai T, Nadano D, Matsuda T, Yagi H, Kato K, Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26110709
[Presentation] アダムズ-オリバー症候群に関連するEOGT遺伝子変異はER型O-GlcNAc修飾の欠損を引き起こす
- Author(s)
  小川光貴, 河合崇生, 灘野大太, 松田幹, 矢木宏和, 加藤晃一, 古川鋼一, 岡島徹也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291020
[Presentation] Impaired O-GlcNAc Modification in the Endoplasmic Reticulum by Mutated EOGT Assosiated with Adams-Oliver Syndrome.
- Author(s)
  Ogawa M, Kawai T, Nadano D, Matsuda T, Yagi H, Kato K, Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25670140
[Presentation] Impaired O-GlcNAc Modification in the Endoplasmic Reticulum by Mutated EOGT Assosiated with Adams-Oliver Syndrome.
- Author(s)
  Ogawa M, Kawai T, Nadano D, Matsuda T, Yagi H, Kato K, Furukawa K, Okajima T.
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  Honolulu, USA
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26291020

1. Takeuchi Hideyuki (80361608)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. 小川光貴 (70727429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
3. KUROSAKA AKIRA (90186536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松田幹 (20144131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 灘野大太 (00228074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 竹下享典 (70444403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 近藤裕史 (50644655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. LO PEIWEN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAWASHIMA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SAWAGUCHI SHOGO

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. YAMAUCHI Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 藤城光弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 中村正直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 古川鋼一

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
15. 古川圭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
16. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 長江雅倫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田嶌優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okajima Tetsuya 岡島 徹也

OKAJIMA Tetsuya 岡島 徹也

Research Projects

Research Products

Co-Researchers

糖転移酵素群によるNOTCHタンパク質の分泌・分解の仕分け機構の解明Principal Investigator

Principal Investigator

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加齢に伴う運動能力低下におけるNotch1上の細胞外O-GlcNAc機能の解明Principal Investigator

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Regulation of Notch signaling in muscle satellite cells by O-glucose glycosylation

Principal Investigator

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Integrated analysis of atypical glycosylation as a basis for precise regulation of Notch signaling in the vascular endotheliumPrincipal Investigator

Principal Investigator

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Roles of Notch signaling and hexosamine pathway on regulation of blood brain barrierPrincipal Investigator

Principal Investigator

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細胞外O-GlcNAc修飾のNotchシグナルと血管形成における役割（国際共同研究強化）Principal Investigator

Principal Investigator

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小胞体GlcNAc修飾の神経組織での役割Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Roles of extracellular O-GlcNAc on Notch signaling and vascular developmentPrincipal Investigator

Principal Investigator

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Functional analysis of orphan glycolsyltransferases associated with congenital muscular dystrophies using model organismsPrincipal Investigator

Principal Investigator

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Research Institution

神経組織の機能発現に関与する新規ドメイン特異糖鎖の解析Principal Investigator

Principal Investigator

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Review Section

Research Institution

Biological and biochemical analyses of Drosophilamutants lacking a novel O-GlcNAc modificationPrincipal Investigator

Principal Investigator

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Research Institution

Identification of a novel post-translational modification of epidermal growth factor domains and mechanistic analysis of the modificationPrincipal Investigator

Principal Investigator

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Research Institution

腸上皮細胞および二枚貝中腸腺細胞へのノロウイルスVLPの結合と細胞応答

Principal Investigator

Project Period (FY)

Okajima Tetsuya 岡島徹也

OKAJIMA Tetsuya 岡島徹也