Watanabe Takaaki 渡邊孝明

… Alternative Names

WATANABE Takaaki 渡邊孝明

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Researcher Number	20421365
Other IDs
Affiliation (Current)	2025: 東海大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 東海大学, 医学部, 講師 2011: 基礎生物学研究所, 多様性生物学研究室, 助教 2010: 基礎生物学研究所, ゲノム動態研究部門, 助教 2009: National Institute for Basic Biology, ゲノム生態研究部門, 助教 2006 – 2008: 基礎生物学研究所, ゲノム動態研究部門, 助教
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 63020:Radiation influence-related / Basic Section 43010:Molecular biology-related Except Principal Investigator Molecular biology / Basic Section 43050:Genome biology-related
Keywords	Principal Investigator 癌 / DGCR8 / 紫外線 / R-loop / 遺伝子進化 / 生体機能利用 / ゲノム / バイオテクノロジー / 遺伝子増幅 / m6A修飾 … More / 選択的スプライシング / ゲノム不安定性 / 複製ストレス / タンパク質間相互作用 / DHX9 / 転写共役ヌクレオチド除去修復 / DEAD-boxヘリカーゼ / TC-NER / 皮膚癌 / DNA複製ストレス / DNA修復 / 逆位反復配列 / ガン / 遺伝子治療 / タンパク質医薬 … More Except Principal Investigator DNA修復 / がん / microRNA / 紫外線 / 分子生物学 / シグナル伝達 / Fanconi anemia / DNA損傷･修復 / 癌 / リン酸化 / 抗がん剤感受性 / ファンコニ貧血 / DNA損傷応答 / RFB(複製フォーク阻害部位) / Fob1タンパク質 / リピート構造 / リボゾームRNA遺伝子 / 複製阻害部位(RFB) / ダブルローリングサークル複製 / 遺伝子進化 / コンデンシン / Cre-lox / ダブルローリングサークル複製(DRCR) / がん遺伝子 / リボソームRNA遺伝子 / 遺伝子増幅 / 制御 / 再編 / 転写装置 / 遺伝子情報複製 Less

Elucidation of regulatory networks of UV-induced RNA-associated damage response involving the multifunctional RNA-binding factor DGCR8.Principal Investigator
- Principal Investigator
  
  渡邊孝明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Tokai University
The novel roles of microRNA biogenesis factors in DNA repair
- Principal Investigator
  
  谷口俊恭
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokai University
Establishment of a comprehensive model for understanding genotoxic R-loop in cancer cellsPrincipal Investigator
- Principal Investigator
  
  WATANABE Takaaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokai University
Regulation of the Fanconi anemia-BRCA pathway
- Principal Investigator
  
  TANIGUCHI Toshiyasu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
- Research Field
  
  Molecular biology
- Research Institution
  Tokai University
Experimental validation of the significance of and molecular mechanism for gene amplification phenomenaPrincipal Investigator
- Principal Investigator
  
  WATANABE Takaaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute for Basic Biology
Mechanism of gene amplification and its function in microorganisms
- Principal Investigator
  
  HORIUCHI Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute for Basic Biology
Analysis and application of molecular mechanism responsible for gene amplification by using a novel amp lification system.Principal Investigator
- Principal Investigator
  
  WATANABE Takaaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute for Basic Biology

All 2023 2021 2018 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation Patent

[Journal Article] Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification2011
- Author(s)
  渡邊孝明、田辺秀之、堀内嵩
- Journal Title
  
  Nucleic Acid Res
  
  Volume: 39 Issue: 16 Pages: e106-e106
- DOI
  10.1093/nar/gkr442
- NAID
  120006576055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770194
[Journal Article] Double rolling circle replication(DRCR) is recombinogenic2011
- Author(s)
  岡本治子、渡邊孝明、堀内嵩
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Pages: 503-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770194
[Journal Article] Double rolling circle replication (DRCR) is recombinogenic2011
- Author(s)
  岡本治子、渡邊孝明、堀内嵩
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Pages: 503-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770194
[Patent] 遺伝子増幅法2007
- Inventor(s)
  堀内嵩、渡邊孝明
- Industrial Property Rights Holder
  自然科学研究機構
- Acquisition Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18770161
[Patent] 遺伝子増幅2006
- Inventor(s)
  堀内嵩、渡邊孝明
- Industrial Property Rights Holder
  大学共同利用法人自然科学研究機構
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-18207013
[Presentation] 線維芽細胞におけるUV-A誘導性酸化ストレスに対するDGCR8の新たな機能解析2023
- Author(s)
  星合快盛,谷口俊恭, 渡邊孝明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] miRNA生合成因子Droshaの紫外線損傷応答を司る新たな機能2023
- Author(s)
  小林滝,谷口俊恭, 渡邊孝明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] 紫外線に対するDNA修復複合体の新たな制御因子DGCR82023
- Author(s)
  渡邊孝明, 谷口俊恭
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] DNA複製の障害となるR-loopのDGCR8依存的制御機構の解析2023
- Author(s)
  善浪大雄,谷口俊恭, 渡邊孝明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] microRNA生合成因子DGCR8のDNA修復における役割2021
- Author(s)
  谷口俊恭、渡邊孝明
- Organizer
  日本放射線影響学会_第64回大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] 紫外線に対するDNA修復複合体の新たな制御因子DGCR82021
- Author(s)
  渡邊孝明、谷口俊恭
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K21303
[Presentation] A new regulatory factor, DGCR8, for the complex formation repairing UV-damaged DNA.2021
- Author(s)
  Takaaki Watanabe, Toshiyasu Taniguchi
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K06493
[Presentation] microRNA生合成タンパクDGCR8による転写と共役したヌクレオチド除去修復の制御機構2018
- Author(s)
  谷口俊恭、渡邊孝明
- Organizer
  第41回日本分子生物学会例会
- Invited
- Data Source
  KAKENHI-PROJECT-15K21771
[Presentation] CHO細胞で高速・確実なタンパク質生産を可能にするシステム2012
- Author(s)
  渡邊孝明
- Organizer
  新技術説明会
- Place of Presentation
  JST東京別館(東京都)
- Year and Date
  2012-02-10
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2011
- Author(s)
  渡邊孝明
- Organizer
  第83回日本遺伝学会
- Place of Presentation
  京都大学農学部(京都府)(招待講演)
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication (DRCR)2011
- Author(s)
  渡邊孝明
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Steamboad Grand Resort(米国)
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication(DRCR)2011
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Steamboad Grand Resort(USA)
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2011
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  日本遺伝学会第83回大会(招待講演)
- Place of Presentation
  京都大学農学部(京都府)
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication (DRCR)2010
- Author(s)
  渡邊孝明
- Organizer
  The 57th NIBB Conference
- Place of Presentation
  岡崎コンファレンスセンター(愛知県)
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2010
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  ポートピアホテル(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication(DRCR)2010
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  The 7th 3R symposium
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication(DRCR)2010
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  The 57th NIBB Conference
- Place of Presentation
  岡崎コンファレンスセンター(愛知県)
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2010
- Author(s)
  渡邊孝明
- Organizer
  第82回日本分子生物学会
- Place of Presentation
  ポートピアホテル(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2010
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  北海道大学高等教育機能開発総合センター(北海道)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル2010
- Author(s)
  渡邊孝明
- Organizer
  第82回日本遺伝学会
- Place of Presentation
  北海道大学高等教育機能開発総合センター(北海道)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] A comprehensive model of gene amplification centering on double rolling-circle replication (DRCR)2010
- Author(s)
  渡邊孝明
- Organizer
  The 7th 3R symposium
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] 誘導可能な新規遺伝子増幅系の開発2009
- Author(s)
  渡邊孝明
- Organizer
  第81回日本遺伝学会
- Place of Presentation
  信州大学理学部(長野県)
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] Development of novel inducible gene amplification systems2009
- Author(s)
  渡邊孝明
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] 誘導可能な新規遺伝子増幅系の開発2009
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  信州大学理学部(長野県)
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] Development of novel inducible gene amplification systems2009
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21770194
[Presentation] 誘導可能な新規遺伝子増幅系の開発2008
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  日本遺伝学会第80回大会
- Place of Presentation
  名古屋大学工学部IB電子情報館
- Year and Date
  2008-09-04
- Data Source
  KAKENHI-PROJECT-18770161
[Presentation] 誘導可能な新規遺伝子増幅系の開発2008
- Author(s)
  渡邊孝明
- Organizer
  第80回日本遺伝学会
- Place of Presentation
  愛知県名古屋市名古屋大学
- Year and Date
  2008-09-04
- Data Source
  KAKENHI-PROJECT-18770161
[Presentation] Gene amplification can be induced under the excessive silencing by the over expression of Sir2p and Sir3p in Saccharomyces cerevisiae2008
- Author(s)
  岡本治子、渡邊孝明、堀内嵩
- Organizer
  第31回分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18207013
[Presentation] 誘導可能な新規遺伝子増幅系の開発2008
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  遺伝学会80回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18207013
[Presentation] 誘導可能な新規遺伝子増幅系の開発2008
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  日本遺伝学会第80回大会
- Place of Presentation
  名古屋大学(愛知)
- Year and Date
  2008-09-04
- Data Source
  KAKENHI-PROJECT-18207013
[Presentation] Cre-lox系を利用した出芽酵母による新規遺伝子増幅系の開発2007
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18770161
[Presentation] Cre-lox系を利用した出芽酵母による新規遺伝子増幅系の開発2007
- Author(s)
  渡邊孝明
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18770161
[Presentation] Cre-loxを利用した出芽酵母による新規遺伝子増幅系の開発2007
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18207013
[Presentation] 新しい高速遺伝子増幅系-タンパク質医薬低コスト化を目指して2006
- Author(s)
  渡邊孝明、堀内嵩
- Organizer
  イノベーション・ジャパン2006新技術説明会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-18770161

1. TANIGUCHI Toshiyasu (60794534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. ISHII Takamasa (20548680)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HORIUCHI Takashi (60108644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. JOHZUKA Katuki (40291893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOBAYASHI Takehiko (40270475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMASAKI Hiroyuki (90837816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANAKA Yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Watanabe Takaaki 渡邊 孝明

WATANABE Takaaki 渡邊 孝明

Research Projects

Research Products

Co-Researchers

Elucidation of regulatory networks of UV-induced RNA-associated damage response involving the multifunctional RNA-binding factor DGCR8.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The novel roles of microRNA biogenesis factors in DNA repair

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a comprehensive model for understanding genotoxic R-loop in cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of the Fanconi anemia-BRCA pathway

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental validation of the significance of and molecular mechanism for gene amplification phenomenaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of gene amplification and its function in microorganisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis and application of molecular mechanism responsible for gene amplification by using a novel amp lification system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Double rolling circle replication(DRCR) is recombinogenic2011

Author(s)

Journal Title

Data Source

[Journal Article] Double rolling circle replication (DRCR) is recombinogenic2011

Author(s)

Journal Title

Data Source

[Patent] 遺伝子増幅法2007

Inventor(s)

Industrial Property Rights Holder

Acquisition Date

Data Source

[Patent] 遺伝子増幅2006

Inventor(s)

Industrial Property Rights Holder

Filing Date

Data Source

[Presentation] 線維芽細胞におけるUV-A誘導性酸化ストレスに対するDGCR8の新たな機能解析2023

Author(s)

Organizer

Data Source

[Presentation] miRNA生合成因子Droshaの紫外線損傷応答を司る新たな機能2023

Author(s)

Organizer

Data Source

[Presentation] 紫外線に対するDNA修復複合体の新たな制御因子DGCR82023

Watanabe Takaaki 渡邊孝明

WATANABE Takaaki 渡邊孝明