YOSHIYAMA Mitsuharu 芳山充晴

Researcher Number	20422694
Other IDs	https://orcid.org/0000-0001-8695-884X
Affiliation (Current)	2024: 山梨大学, 大学院総合研究部, 研究員
Affiliation (based on the past Project Information) *help	2022: 山梨大学, 大学院総合研究部, 研究員 2020 – 2021: 山梨大学, 大学院総合研究部, 医学研究員 2017 – 2018: 山梨大学, 大学院総合研究部, 医学研究員 2015 – 2016: 山梨大学, 総合研究部, 医学研究員 2014 – 2015: 山梨大学, 総合研究部, 教授 … More 2012 – 2013: 山梨大学, 医学工学総合研究部, 教授 2012: 山梨大学, 大学院・医学工学総合研究部, 教授 2011: 山梨大学, 医学工学総合研究部, 医学研究員 2011: 山梨大学, 医学部, 非常勤講師 2007 – 2011: University of Yamanashi, 大学院・医学工学総合研究部, 医学研究員 Less
Review Section/Research Field	Principal Investigator Urology / Basic Section 56030:Urology-related Except Principal Investigator Urology / Fundamental nursing
Keywords	Principal Investigator マウス / 外尿道括約筋 / 膀胱 / 排尿障害 / 脊髄損傷 / 下部尿路機能 / 代謝型グルタミン酸 / 興奮性グルタミン酸受容体 / 神経ペプチド / 尿道 … More / 代謝型グルタミン酸受容体 / グルタミン酸 / 神経成長因子 / グルタミン酸受容体 / 神経栄養因子前駆体 / 神経栄養因子 / 排尿機能学 / 酸感受性イオンチャネル / 蓄尿障害 / 求心路 / 膀胱過活動 / 酸感受性チャネル / 末梢神経 / 中枢神経 / 酸感受性イオンチャンネル / 慢性脊髄損傷 / 下部尿路機能制御 / 膀胱活動 / 外尿道括約筋活動 / 末梢神経障害 / 神経障害 / 切迫性尿失禁 / 尿意切迫感 / 反射排尿 / 残尿 / 排尿収縮圧 / 膀胱コンプライアンス / 脊髄 / 下部尿路障害 / 低活動膀胱 / 脳下垂体アデニル酸シクラーゼ活性化ポリペプチド(PACAP) / 糖尿病 … More Except Principal Investigator ATP / メカノセンサー / イオンチャネル / 夜間頻尿 / Piezo1 / 間質性膀胱炎 / 膀胱 / 膀胱上皮 / 尿路上皮 / TRPV4 / TRP / 機械センサー / 時計遺伝子 / 動的恒常性 / 下部尿路機能 / 排尿機能学 / ＴＲＰチャネル / 時計遺伝子異常 / P2Y6受容体欠損マウス / 発症機序 / 動的恒常性破綻 / 複雑系ネットワーク / 下部尿路機能障害 / metabolomics / noctrunal polyuria / clock gene / nocturia / Biomarker / Metabolomics / Mechanosensor / Clock genes / Lower urinary tract / アクチグラフ / アクチクラフ / 入浴 / アクチグラム / 排尿日誌 / 足浴 / 高齢者 / 多国籍 / 国際情報交流 / ペインコントロール / 附子 / 漢方 / 慢性疼痛症候群 / 神経障害性疼痛 / ボツリヌス毒素 / トリカブト / 附子（トリカブト） / ボツリヌストキシン / 漢方治療 / 蓄尿障害 / 求心性シグナル伝達 / ＴＲＰＶ４ / TRPV４ / P2Y6 / PIEZO / VNUT / Overactive bladder / Urinary bladder / Afferent nerve / 上皮 / 酸 / 膀胱炎 / イオンチャンネル / 排尿 / 炎症 / 痛み / 知覚 / 求心性伝達機構 / 過活動膀胱 / TRP TRPV4 / 細胞内カルシウムイオン / 膀胱上皮細胞 Less

Analysis of action of neurotrophic factor precursor via glutamatergic signal transmission that is involved in voiding dysfunction after spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Yamanashi
Functional analysis of the metabotropic glutamate receptor and the acid-sensitive ion channels as a urine collection control moleculePrincipal Investigator
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Studies on lower urinary tract dysfunction pathogenesis by complex systems network and dynamic homeostasis collapse
- Principal Investigator
  
  TAKEDA Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Plastic changes in transmission of neuropeptide and metabotropic glutamate related to voiding dysfunction after chronic spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Effects of evening foot bathing on older adults with night nocturia for night urination status and sleep status
- Principal Investigator
  
  KOBAYASHI TATSUKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Fundamental nursing
- Research Institution
  Nagano College of Nursing
  Yamanashi Prefectural University
Research on the afferent transduction in the lower urinary tract
- Principal Investigator
  
  TAKEDA Masayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Involvements of TRPV1 and TRPV4 channels in regulatory function to maintain bladder stability during urine storage: integrated analysis of behavior and reflex
- Principal Investigator
  
  MOCHIZUKI Tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
The mechanism of action of aconite and botulinum toxin for interstitial cystitis pain
- Principal Investigator
  
  TSUCHIDA Takayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Strategy targeting neuropeptide receptors in the central and peripheral nervous systems in treatment of underactive bladderPrincipal Investigator
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Contribution of acid-sensing nociceptor molecules (ASIC and TRPV1) to symptom onset in interstitial cystitis
- Principal Investigator
  
  ARAKI Isao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
  University of Yamanashi
Reseaarch on the function and development of new therapy for Ion channels in the lower urinary tract
- Principal Investigator
  
  TAKEDA Masayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Elucidation of pathophysiology in voiding dysfunction after spinal cord injury and its treatments : a study on functional roles of spinal metabotropic glutamatergic mechanismPrincipal Investigator
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi

[Book] Handbook of Neurourology: Theory and Practice2023
- Author(s)
  YOSHIYAMA, Mitsuharu、KAKIZAKI, Hidehiro
- Total Pages
  19
- Publisher
  Springer Singapore
- Data Source
  KAKENHI-PROJECT-20K09575
[Book] Handbook of Neurourology: Theory and Practice2022
- Author(s)
  Mitsuharu Yoshiyama, Hidehiro Kakizaki
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-20K09575
[Book] Spinal cord, In: Neurourology: theory and practice (Eds. Limin Liao, Helmut Madersbacher)2019
- Author(s)
  Yoshiyama Mitsuharu、Kakizaki Hidehiro
- Total Pages
  583
- Publisher
  Springer, Dordrecht
- ISBN
  9789401775090
- Data Source
  KAKENHI-PROJECT-16K11042
[Journal Article] Blockade of acid-sensing ion channels increases urinary bladder capacity with or without intravesical irritation in mice2020
- Author(s)
  Yoshiyama, M., Kobayashi, H., Takeda, M., Araki, I.
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 11 Pages: 592867-592867
- DOI
  10.3389/fphys.2020.592867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09575
[Journal Article] Best practices for cystometric evaluation of lower urinary tract function in muriform rodents2020
- Author(s)
  Fraser, M.O., Smith, P.P., Sullivan, M.P., Bjorling, D.E., Campeau, L., Andersson, K.-E., Yoshiyama, M.
- Journal Title
  
  Neurourology and Urodynamics
  
  Volume: 39 Issue: 6 Pages: 1868-1884
- DOI
  10.1002/nau.24415
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09575
[Journal Article] The effect of Ferula elaeochytris root extract on erectile dysfunction in streptozotocin-induced diabetic rat2019
- Author(s)
  Eser Nadire、Buyuknacar Hacer Sinem、Cimentepe Ozge Ozturk、Gocmen Cemil、Ucar Yilmaz、Erdogan Seyda、Yoshiyama Mitsuharu
- Journal Title
  
  International Journal of Impotence Research
  
  Volume: 印刷中 Issue: 2 Pages: 186-194
- DOI
  10.1038/s41443-019-0137-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-20K09575
[Journal Article] The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium2018
- Author(s)
  Ihara Tatsuya、Mitsui Takahiko、Nakamura Yuki、Kanda Mie、Tsuchiya Sachiko、Kira Satoru、Nakagomi Hiroshi、Sawada Norifumi、Kamiyama Manabu、Hirayama Yuri、Shigetomi Eiji、Shinozaki Youichi、Yoshiyama Mitsuharu、Nakao Atsuhito、Takeda Masayuki、Koizumi Schuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5699-5699
- DOI
  10.1038/s41598-018-23115-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11175, KAKENHI-PROJECT-18K06481, KAKENHI-PUBLICLY-18H05121, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-16H04669
[Journal Article] The time-dependent variation of ATP release in mouse primary cultured urothelial cells is regulated by the Clock gene.2018
- Author(s)
  Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Hirayama Y, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M Koizumi S
- Journal Title
  
  Neurourology and urodynamics
  
  Volume: 37 Issue: 8 Pages: 2535-2543
- DOI
  10.1002/nau.23793
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11175, KAKENHI-PUBLICLY-18H05121, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-16H04669
[Journal Article] Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury2018
- Author(s)
  Ryu Jae Cheon、Tooke Katharine、Malley Susan E.、Soulas Anastasia、Weiss Tirzah、Ganesh Nisha、Saidi Nabila、Daugherty Stephanie、Saragovi Uri、Ikeda Youko、Zabbarova Irina、Kanai Anthony J.、Yoshiyama Mitsuharu、Farhadi H. Francis、de Groat William C.、Vizzard Margaret A.、Yoon Sung Ok
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 128 Issue: 5 Pages: 1772-1786
- DOI
  10.1172/jci97837
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Journal Article] Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.2017
- Author(s)
  5.Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 1 Pages: e0168234-e0168234
- DOI
  10.1371/journal.pone.0168234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K15524, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-15H04972
[Journal Article] P2Y6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice2017
- Author(s)
  Kira S,Yoshiyama M,Tsuchiya S,Shigetomi E,Miyamoto T,Nakagomi H,Shibata K,Mochizuki T,Takeda M,Koizumi S
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 771-771
- DOI
  10.1038/s41598-017-00824-2
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-17K09032
[Journal Article] Ketanserin and naftopidil enhance the potentiating effect of alpha-methyl-serotonin on the neurally-induced contraction of human isolated urinary bladder muscle strips2017
- Author(s)
  Hattori T, Lluel P, Rouget C, Rekik M, Yoshiyama M
- Journal Title
  
  International Neurourology Journal
  
  Volume: 21 Issue: 1 Pages: 20-28
- DOI
  10.5213/inj.1732758.379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Journal Article] The role of capsaicin-sensitive C-fiber afferent pathways in the control of micturition in spinal-intact and spinal cord-injured mice2017
- Author(s)
  Kadekawa Katsumi、Majima Tsuyoshi、Shimizu Takahiro、Wada Naoki、de Groat William C.、Kanai Anthony J.、Goto Momokazu、Yoshiyama Mitsuharu、Sugaya Kimio、Yoshimura Naoki
- Journal Title
  
  Ａｍｅｒｉｃａｎ　Ｊｏｕｒｎａｌ　ｏｆ　Ｐｈｙｓｉｏｌｏｇｙ　Ｒｅｎａｌ　Ｐｈｙｓｉｏｌｏｇｙ
  
  Volume: 313 Issue: 3 Pages: F796-F804
- DOI
  10.1152/ajprenal.00097.2017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Journal Article] The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells2017
- Author(s)
  Ihara Tatsuya、Mitsui Takahiko、Nakamura Yuki、Kanda Mie、Tsuchiya Sachiko、Kira Satoru、Nakagomi Hiroshi、Sawada Norifumi、Hirayama Yuri、Shibata Keisuke、Shigetomi Eiji、Shinozaki Yoichi、Yoshiyama Mitsuharu、Nakao Atsuhito、Takeda Masayuki、Koizumi Schuichi
- Journal Title
  
  Neurourology and Urodynamics
  
  Volume: 37 Issue: 3 Pages: 942-951
- DOI
  10.1002/nau.23400
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11175, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-17K09032, KAKENHI-PROJECT-18K06481, KAKENHI-PROJECT-16K11042
[Journal Article] The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.2016
- Author(s)
  Ihara, T., Mitsui, T., Nakamura, Y., Kira, S., Miyamoto, T., Nakagomi, H., Sawada, N., Hirayama, Y., Shibata, K., Shigetomi, E., Shinozaki, Y., Yoshiyama, M., Nakao, A., *Takeda, M. *Koizumi, S.
- Journal Title
  
  Neurourology and Urodynamics
  
  Volume: 36 Issue: 4 Pages: 1034-1038
- DOI
  10.1002/nau.23062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-15H04972
[Journal Article] Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase2016
- Author(s)
  Nakagomi H,Yoshiyama M,Mochizuki T,Miyamoto T,Komatsu R,Imura Y,Morizawa Y,Hiasa M,Kira S,Fujishita K,Shibata K,Shigetomi E,Shinozaki Y,Takeda M,Koizumi S
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 29761-29761
- DOI
  10.1038/srep29761
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-26460067, KAKENHI-PROJECT-26461383, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K08230, KAKENHI-PROJECT-16K11042
[Journal Article] Characterization of bladder and external urethral activity in mice with or without spinal cord injury - a comparison study with rats2016
- Author(s)
  Kadekawa K, Yoshimura N, Majima T, Wada N, Shimizu T, Birder LA, Kanai AJ, de Groat WC, Sugaya K, Yoshiyama M
- Journal Title
  
  American Journal of Physiology Regulatory Integrative Comparative Physiology
  
  Volume: 310 Issue: 8 Pages: R752-R758
- DOI
  10.1152/ajpregu.00450.2015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507, KAKENHI-PROJECT-16K11042
[Journal Article] Netupitant, a potent and highly selective NK1 receptor antagonist, alleviates acetic acid-induced bladder overactivity in anesthetized guinea-pigs2016
- Author(s)
  Palea S, Guilloteau V, Rekik M, Lovati E, Guerard M, Guardia MA, Lluel P, Pietra C, Yoshiyama M
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 7
- DOI
  10.3389/fphar.2016.00234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Journal Article] Functional roles of TRPV1 and TRPV4 in control of lower urinary tract activity: dual analysis of behavior and reflex during the micturition cycle2015
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Kira S, Mizumachi R, Sokabe T, Takayama Y, Tominaga M, Takeda M
- Journal Title
  
  American Journal of Physiology Renal Physiology
  
  Volume: 308 Issue: 10 Pages: F1128-F1134
- DOI
  10.1152/ajprenal.00016.2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462507
[Journal Article] Effects of urethane on reflex activity of lower urinary tract in decerebrate unanesthetized rats.2013
- Author(s)
  Yoshiyama M, Roppolo JR, Takeda M, de Groat WC
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Effects of urethane on reflex activity of lower urinary tract in decerebrate unanesthetized rats2013
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  American Journal of Physiology - Renal Physiology
  
  Volume: 304 Issue: 4 Pages: F390-F396
- DOI
  10.1152/ajprenal.00574.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787, KAKENHI-PROJECT-24592426, KAKENHI-PROJECT-25462507
[Journal Article] 医薬ジャーナル2013
- Author(s)
  武田正之、荒木勇雄、澤田智史、中込宙史、望月勉、小林英樹、座光寺秀典、芳山充晴
- Journal Title
  
  新薬展望2013
  
  Volume: Vol.49 S-1
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Expression of large conductance, voltage- and Ca2+-activated K+ (BK) channels in human urinary bladder: alteration of subunit expression profile in association with bladder outlet obstruction2013
- Author(s)
  Zakoji, H., Kobayashi, H., Yoshiyama, M., Takeda, M., Araki, I.
- Journal Title
  
  Open Journal of Urology
  
  Volume: 3 Issue: 02 Pages: 47-52
- DOI
  10.4236/oju.2013.32009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462507
[Journal Article] Effects of Urethane on reflex activity of lower urinary tract in decerebrate unanesthetized rats.2013
- Author(s)
  Mitsuharu Yoshiyama, Roppolo, James, R., Masayuki Takeda, William C. de Groat
- Journal Title
  
  Am.J.Physiol., Renal Physiol.
  
  Volume: 30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390381
[Journal Article] Distribution and possible function of cannabinoid receptor subtype 1 in the human prostate2013
- Author(s)
  Kamiyama, M., Fukasawa, M., Takihana, Y., Sawada, N., Nakagomi, H., Yoshiyama, M., Araki, I., Takeda, M.
- Journal Title
  
  Open Journal of Urology
  
  Volume: 3 Issue: 02 Pages: 102-109
- DOI
  10.4236/oju.2013.32020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462507
[Journal Article] 中枢性グルタミン酸，モノアミン作動性下部尿路機能制御2013
- Author(s)
  芳山充晴
- Journal Title
  
  山梨医科学誌
  
  Volume: 28(1) Pages: 17-29
- NAID
  110009623367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462507
[Journal Article] 排尿障害におけるβ3受容体作動薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  Progress in Medicine
  
  Volume: Vol.32 (No.4) Pages: 37-42
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 排尿障害におけるβ3受容体刺激(作動)薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  診断と治療
  
  Volume: 第100巻・第8号 Pages: 1379-1385
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] VNUT(Vesicular Nucleotide Transporter)を介する膀胱上皮からのATP放出メカニズム2011
- Author(s)
  中込宙史、望月勉、芳山充晴、宮本達也吉良聡、川原和也、荒木勇雄、小泉修一森山芳則、武田正之
- Journal Title
  
  日本排尿機能学会誌
  
  Volume: Vol.22(1) Pages: 121-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] Bladder outlet obstruction induced expression of prostaglandin E2receptor subtype EP4 in the rat bladder: a possible counteractive mechanism against detrusor overactivity2011
- Author(s)
  Beppu M, Araki I, Yoshiyama M, Du S, Kobayashi H, Zakoji H, Takeda M.
- Journal Title
  
  J Urol
  
  Volume: 186 Pages: 2463-2469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 第4回国際尿失禁会議からの報告 Committee3 Cell Biology 「細胞生物学」2011
- Author(s)
  武田正之、中込宙史、宮本達也、吉良聡、芳山充晴
- Journal Title
  
  排尿障害プラクティス
  
  Volume: Vol.19(1) Pages: 66-88
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Bladder outlet obstruction induced expression of prostaglandin E2receptor subtype EP4 in the rat urinary bladder: a possible counteractive mechanism against detrusor overactivity2011
- Author(s)
  Beppu M, Araki I, Yoshiyama M, Du S, Kobayashi H, Zakoji H, Takeda M
- Journal Title
  
  J Urol
  
  Volume: 186(6) Issue: 6 Pages: 2463-2469
- DOI
  10.1016/j.juro.2011.07.087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068, KAKENHI-PROJECT-22591787
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid: in-vivo evaluations on the sex difference in decerebrate unanesthetized mice2010
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390423
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid: in vivo evaluations of the sex difference in decerebrate unanesthetized mice2010
- Author(s)
  Yoshiyama M, Araki I, Kobayashi H, Zakoji H, Takeda M.
- Journal Title
  
  Am.J.Physiol.Renal.Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Emerging families of ion channel involved in urinary bladder nociception2010
- Author(s)
  Araki I, Yoshiyama M, Kobayashi H, Mochizuki M, Du S, Okada Y, Takeda M
- Journal Title
  
  Pharmaceuticals
  
  Volume: 3(7) Issue: 7 Pages: 2248-2267
- DOI
  10.3390/ph3072248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] Sensor mechanism and afferent signal transduction of the urinary bladder: special focus on transient receptor potential ion channels2010
- Author(s)
  Takeda M, Mochizuki T, Yoshiyama M, Nakagomi H, Kobayashi H, Sawada N, Zakohji H, Du S, Araki I
- Journal Title
  
  LUTS (Lower Urinary Tract Symptoms)
  
  Volume: 2 Pages: 51-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 排尿障害の基礎2010
- Author(s)
  芳山充晴
- Journal Title
  
  臨床検査
  
  Volume: Vol.54(7) Pages: 717-725
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Emerging families of ion channels involved2010
- Author(s)
  Araki I,Yoshiyama M,Kobayashi H,Mochizuki T,Du S,Okada Y,Takeda M.
- Journal Title
  
  urinary bladder nociception Pharmaceuticals
  
  Volume: 3 Pages: 2248-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid2010
- Author(s)
  Mitsuharu Yoshiyama, Isao Araki, Hideki Kobayashi, Hidenori Zakoji, Masayuki Takeda
- Journal Title
  
  in-vivo evaluations on the sex difference in decerebrate unanesthetized mice Am J Physiol Regul Integr Comp Physiol 298
  
  Pages: 1351-1359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390423
[Journal Article] Emerging families of ion channel involved in urinary bladder nociception.2010
- Author(s)
  Araki I, Yoshiyama M, Kobayashi H, Mochizuki M, Du S, Okada Y, Takeda M
- Journal Title
  
  Pharmaceuticals
  
  Volume: 3 Pages: 2248-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] Sensor mechanism and afferent signal transduction of the urinary bladder: special focus on TRP ion channels2010
- Author(s)
  Takeda M, Mochizuki T, Yoshiyama M, Nakagomi H, Kobayashi H, Sawada N, Zakoji H, Du S, Araki I
- Journal Title
  
  LUTS: Lower Urinary Tract Symptoms
  
  Volume: 2(2) Issue: 2 Pages: 51-60
- DOI
  10.1111/j.1757-5672.2010.00074.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid: in-vivo evaluations on the sex difference in decerebrate unanesthetized mice2010
- Author(s)
  Yoshiyama M, Araki I, Kobayashi H, Zakoji H, Takeda M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 298 Issue: 6 Pages: F1351-F1359
- DOI
  10.1152/ajprenal.00695.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid : in-vivo evaluations on the sex difference in decerebrate unanesthetized mice.2010
- Author(s)
  Yoshiyama M, Araki I, Kobayashi H, Zakoji H, Takeda M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] 排尿障害の基礎.2010
- Author(s)
  芳山充晴
- Journal Title
  
  臨床検査
  
  Volume: 54(7) Pages: 717-725
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 尿路上皮と排尿2010
- Author(s)
  荒木勇雄、中込宙史、望月勉、小林英樹、芳山充晴、武田正之
- Journal Title
  
  臨床検査
  
  Volume: Vol.54(7) Pages: 726-730
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid: in vivo evaluations of the sex difference in decerebrate unanesthetized mice.2010
- Author(s)
  Yoshiyama M, et al.
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 298 Pages: 1351-1359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Glutamatergic mechanisms controlling the lower urinary tract function2009
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  LUTS (Lower Urinary Tract Symptoms) (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Sex differences in the expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms.2009
- Author(s)
  Kobayashi, H., Yoshiyama, M., Zakoji, H., Takeda, M., Araki, I.
- Journal Title
  
  BJU Int. 104
  
  Pages: 1746-1751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390423
[Journal Article] Mechanosensitive ion channels in bladder sensory transduction2009
- Author(s)
  Araki I, Du S, Kobayashi H, Yoshiyama M, Takeda M
- Journal Title
  
  LUTS: Lower Urinary Tract Symptoms
  
  Volume: 1(Suppl 1) Issue: s1
- DOI
  10.1111/j.1757-5672.2009.00021.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] Sex differences in expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms2009
- Author(s)
  Kobayashi H, Yoshiyama M, Zakoji H, Takeda M, Araki I
- Journal Title
  
  BJU Int
  
  Volume: 104(11) Issue: 11 Pages: 1746-1751
- DOI
  10.1111/j.1464-410x.2009.08658.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592068
[Journal Article] The role of vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide in the neural pathways controlling the lower urinary tract.2008
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Journal of Molecular Neuroscience (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] 蓄尿障害(1)排尿筋弛緩-排尿筋過活動抑制 : 抗ムスカリン薬, β3受容体活性薬, BKチャンネル, その他2008
- Author(s)
  芳山充晴
- Journal Title
  
  排尿障害プラクティス 16(3)
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Sex-related differences in activity of lower urinary tract in response to intravesical acid irritation in decerebrate unanesthetized mice2008
- Author(s)
  Yoshiyama, M, Kobayashi, H., Araki, l., Du, S., Zakoji, H., Takeda, M.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol 295(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390423
[Journal Article] Effects of intrathecal administration of pituitary adenylate cyclase activating polypeptide on lower urinary tract functions in rats with intact or transected spinal cords2008
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Experimental Neurology 211
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] The role of vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide in the neural pathways controlling the lower urinary tract2008
- Author(s)
  Yoshiyama, M, and de Groat, W.C.
- Journal Title
  
  J. Mol. Neurosci 36
  
  Pages: 227-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Effects of intrathecal administration of pituitary adenylate cyclase activating polypeptide on lower urinary tract functions in rats with intact or transected spinal cords2008
- Author(s)
  Yoshiyama, M, and de Groat, W.C.
- Journal Title
  
  Exp. Neurol 211
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] The role of vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide in the neural pathways controlling the lower urinary tract2008
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Journal of Molecular Neuroscience 36
  
  Pages: 227-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Sex-related differences in activity of lower urinary tract in response to intravesical acid irritation in decerebrate unanesthetized mice2008
- Author(s)
  Yoshiyama, M., Kobayashi, H., Araki, I., Du, S., Zakoji, H., and Takeda, M.
- Journal Title
  
  Am. J. Physiol. Regul. Integr. Comp. Physiol 295
  
  Pages: 954-960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Sex-related differences in activity of lower urinary tract in response to intravesical acid irritation in decerebrate unanesthetized mice2008
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  American Journal of Physiology Regulatory Integrative Comparative Physiology 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Effects of intrathecal administration of pituitary adenylate cyclase activating polypeptide on lower urinary tract functions in rats with intact or transected spinal cords.2008
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Experimental Neurology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] 蓄尿障害(1)排尿筋弛緩-排尿筋過活動抑制 : 抗ムスカリン薬, β3受容体活性薬, BKチャンネル, その他2008
- Author(s)
  芳山充晴
- Journal Title
  
  排尿障害プラクティス Vol.16(3)
  
  Pages: 9-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Amiloride-sensitive ion channels in urinary bladder epithelium involved in mechanosensory transduction by modulating stretch-evoked adenosine triphosphate release2007
- Author(s)
  Du, S., Araki, I., Mikami, Y., Zakoji, H., Beppu, M., Yoshiyama, M., and Takeda, M.
- Journal Title
  
  Urology 69
  
  Pages: 590-595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway2007
- Author(s)
  Du, S., Araki, I., Yoshiyama, M., Nomura, T., and Takeda, M.
- Journal Title
  
  Urology 70
  
  Pages: 826-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Role of spinal metabotropic glutamate receptors in regulation of lower urinary tract function in the decerebrate unanesthetized rat2007
- Author(s)
  Yoshiyama, M, and de Groat, W.C.
- Journal Title
  
  Neurosci. Lett. 420
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Role of spinal metabotropic glutamate receptors in regulation of lower urinary tract function in the decerebrate unanesthetized rat.2007
- Author(s)
  Mitsuharu Yoshiyama
- Journal Title
  
  Neuroscience Letters 420
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Glutamatergic mechanisms controlling the lower urinary tract function
- Author(s)
  Yoshiyama, M.
- Journal Title
  
  LUTS (Lower Urinary Tract Symptoms) (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Journal Article] Sex differences in expression profile of acid-sensing ion channels in the mouse urinary bladder : a possible involvement in irritative bladder symptoms
- Author(s)
  Kobayashi, H., Yoshiyama, M., Zakoji, H., Takeda, M., and Takeda, M.
- Journal Title
  
  BJU Int. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Acid-sensing ion channel 3 (ASIC3) inhibitor increases functional bladder capacity with or without acidic irritation of lower urinary tract in mice when administering intraperitoneally but not intravesically2020
- Author(s)
  Yoshiyama, M.
- Organizer
  International Continence Society 2020 Online Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09575
[Presentation] The sex influences metabotropic glutamate receptor subtype 1 phenotype in control of lower urinary tract activity2018
- Author(s)
  Yoshiyama Mitsuharu、Mochizuki Tsutomu、Takeda Masayuki
- Organizer
  International Continence Society 48th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] マウス下部尿路機能制御において性別は代謝型グルタミン酸受容体サブタイプ１表現型へ有意に影響する2018
- Author(s)
  芳山充晴、望月勉、武田正之
- Organizer
  第25回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Metabotropic glutamate receptor subtypes 1 and 5 are necessary for synergic activity of bladder and external urethral sphincter in mice with spinal cord injury2018
- Author(s)
  M Yoshiyama, M Takeda
- Organizer
  European Association of Urology Annual congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Metabotropic glutamate receptor subtypes 1 and 5 are necessary for synergic activity of bladder and external urethral sphincter in mice with spinal cord injury2018
- Author(s)
  Yoshiyama Mitsuharu、Takeda Masayuki
- Organizer
  The 33rd Annual Congress of the European Association of Urology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] 代謝型グルタミン酸受容体経路遮断は完全脊髄損傷マウスの排尿機能不全を増悪する2017
- Author(s)
  芳山充晴、武田正之
- Organizer
  第24回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Blockade of metabotropic glutamatergic pathways worsens voiding dysfunction in mice with chronically-transected spinal cord2017
- Author(s)
  M Yoshiyama,M Takeda
- Organizer
  International Continence Society 47th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Effect of restraint stress on alternation of circadian bladder function to induce nocturia2017
- Author(s)
  T Ihara,Y Nakamura,T Mitsui,Y Otake,Y Imai,S Kira,H Nakagomi,N Sawada,M Yoshiyama,S Koizumi,A Nakao,M Takeda
- Organizer
  International Continence Society 47th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Pelvic floor supportive underwear enhances alleviating effect of pelvic floor muscle training on lower urinary tract symptoms in pelvic organ prolapse patients2017
- Author(s)
  T Taniguchi,Y Kobayashi,S Takaoka,H Kobayashi,T Mitsui,M Yoshiyama,M Takeda
- Organizer
  International Continence Society 47th Annual meeting,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Evaluation of a novel underwear which supports the pelvic floor in pelvic organ prolapse patients2016
- Author(s)
  Taniguchi T, Kobayashi Y, Kobayashi H, Mitsui T, Takaoka T, Yoshiyama M, Takeda M
- Organizer
  International Continence Society 46th Annual meeting
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] The role of capsaicin-sensitive C-fiber afferent pathways in the control of micturition in normal mice and lower urinary tract dysfunction in mice with spinal cord injury2016
- Author(s)
  Kadekawa K, Yoshiyama M, Wada N, Shimizu T, Majima T, Tyagi P, Kanai A, de Groat W, Sugaya K, Yoshimura N
- Organizer
  International Continence Society 46th Annual meeting
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Glycine transporter type 2 (GlyT2) inhibitor ameliorates autonomic dysreflexia during bladder hydrodistention and detrusor overactivity in IC/BPS rat model2016
- Author(s)
  Kim SW, Moon SY, Son HS, Yoshiyama M, Kim JH
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  San Diego, California, U.S.A.
- Year and Date
  2016-05-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Characterization of tonic activity of external urethral sphincter during voiding underlying inefficient voiding after spinal cord injury in rats2016
- Author(s)
  Kadekawa K, Yoshiyama M, Majima T, Tyagi P, Sugaya K, Yoshimura N
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  San Diego, California, U.S.A.
- Year and Date
  2016-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Preclinical Urodynamics - Optimisation of Techniques, Measurements and Interpretation2016
- Author(s)
  Yoshiyama M
- Organizer
  International Continence Society 46th Annual meeting
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Metabotropic glutamate receptor subtypes 1 and 5 synergistically modulate bladder filling function in mice2016
- Author(s)
  Mitsuharu Yoshiyama,Masayuki Takeda
- Organizer
  The 31st Annual Congress of the European Association of Urology
- Place of Presentation
  Munich, Germany
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Clock genes regulate circadian rhythm of VNUT expression,Connexin26 expression and stretch-evoked ATP release in the cultured urothelial cells2016
- Author(s)
  Ihara T, Kira S, Miyamoto T, Sawada N, Nakagomi H, Mitsui T, Kobayashi H, Yoshiyama M, Takeda M, Nakamura Y, Nakao A, Shigetomi E, Shinozaki Y, Koizumi S
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  San Diego, California, U.S.A.
- Year and Date
  2016-05-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] Clock genes regulate circadian rhythm of Piezo1 and TRPV4 expressions and intracellular Ca2+ influx after stretch stimulation in the cultured urothelial cells2016
- Author(s)
  Tatsuya Ihara,Satoru Kira,Tatsuya Miyamoto,Norifumi Sawada,Hiroshi Nakagomi,Takahiko Mitsui,Hideki Kobayashi,Mitsuharu Yoshiyama,Masayuki Takeda,Yuki Nakamura,Atsuhito Nakao,Eiji Shigetomi,Keisuke Shibata,Youichi Shinozaki,Syuichi Koizumi
- Organizer
  The 31st Annual Congress of the European Association of Urology
- Place of Presentation
  Munich, Germany
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Circadian regulations of Piezo1, TRPV4, Connexin26 and VNUT by clock genes in the mouse bladder urothelium2016
- Author(s)
  Ihara T, Nakamura Y, Mitsui T, Kira S, Nakagomi H, Sawada N, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S
- Organizer
  International Continence Society 46th Annual meeting
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11042
[Presentation] The long-term effect of a special programme of pelvic floor muscle training for female patients with LUTS in Japan2015
- Author(s)
  Tamami Taniguchi,Hideki Kobayashi,Takahiko Mitsui,Mitsuharu Yoshiyama,Masayuki Takeda
- Organizer
  International Continence Society 45th Annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Purinergic transmission via P2Y6 receptor plays an essential role in bladder storage function in mice2015
- Author(s)
  Satoru Kira, Mitsuharu Yoshiyama, Tatsuya Miyamoto, Hiroshi Nakagomi, Tsutomu　Mochizuki, Eiji Shigetomi, Schuichi　Koizumi, Masayuki Takeda
- Organizer
  29th Annual EAU Congress
- Place of Presentation
  Stockholm(Sweden)
- Year and Date
  2015-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972
[Presentation] Functional roles of metabotropic glutamate receptor subtype 1a in control of lower urinary tract activity in mice2015
- Author(s)
  Mitsuharu Yoshiyama,Tsutomu Mochizuki,Masayuki Takeda
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, U.S.A.
- Year and Date
  2015-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Characterization of bladder and external urethral sphincter activity in mice with or withut spinal cord injury – a comparison study with rats2015
- Author(s)
  Katsumi Kadekawa,Mitsuharu Yoshiyama,Tsuyoshi Majima,Naoki Wada,Takahiro Shimizu,William C. de Groat,Kimio Sugaya　　　　　　　　　　　　,
- Organizer
  International Continence Society 45th Annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] マウス膀胱平滑筋・上皮におけるP2Y6受容体機能の検討2015
- Author(s)
  吉良　聡、芳山充晴、宮本達也、井原達矢、中込宙史、望月　勉、柴田圭輔、繁冨　英治、小泉修一、武田正之
- Organizer
  第103回日本泌尿器科学会
- Place of Presentation
  ホテル金沢、石川県金沢市
- Year and Date
  2015-04-19
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] 過去3年間の過活動膀胱患者におけるミラベグロン服薬継続率：性差、単独と併用の比較2015
- Author(s)
  武田正之、内山秀行、志村寛史、青木　正、大竹裕子、座光寺秀典、宮本達也、三井貴彦、小林英樹、芳山充晴
- Organizer
  第22回日本排尿機能学会
- Place of Presentation
  京王プラザホテル札幌、北海道札幌市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Investigation of LUTS (lower urinary tract symptoms) with pelvic organ prolapse (cystocele)2015
- Author(s)
  Hideki Kobayashi,Tamami Taniguchi,Yuko Ootake,Satoru Kira,Takahiko Mitsui,Hidenori Zakoji,Mitsuiharu Yoshiyama,Masayuki Takeda
- Organizer
  International Continence Society 45th Annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] 時計遺伝子異常による膀胱上皮Piezo1発現の変化と排尿への影響2015
- Author(s)
  井原達矢、吉良　聡、山岸　敬、宮本達也、澤田智史、三井貴彦、芳山充晴、武田正之
- Organizer
  第22回日本排尿機能学会
- Place of Presentation
  京王プラザホテル札幌、北海道札幌市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] 代謝型グルタミン酸受容体1aサブタイプ欠損マウスの下部尿路機能評価2015
- Author(s)
  芳山充晴、望月　勉、武田正之
- Organizer
  第22回日本排尿機能学会
- Place of Presentation
  京王プラザホテル札幌、北海道札幌市
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Roles of metabotropic glutamate receptor subtype 1a in lower urinary tract function of mice2015
- Author(s)
  Mitsuharu Yoshiyama,Tsutomu Mochizuki,Masayuki Takeda
- Organizer
  International Continence Society 45th Annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Clock mutant mouse is a novel experimental model for nocturia/nocturnal polyuria2015
- Author(s)
  Tatsuya Ihara,Satoru Kira,Takashi Yamagishi,Tatsuya Miyamoto,Norifumi Sawada,Mitsuharu Yoshiyama,Masayuki Takeda,Yuki Nakamura,Atsuhito Nakao
- Organizer
  International Continence Society 45th Annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Neither systemic nor intravesical administration of A-317567, an acid-sensing ion channel blocker affect the lower urinary tract activity in decerebrate unanesthetized mice2013
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  International Continence Society 43rd Annual meeting
- Place of Presentation
  Centre Convencions Internacional de Barcelona（Barcelona,Spain)
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Efficacy of the beta3-adrenoceptor agonist mirabegron in patients with stress urinary incontinence2013
- Author(s)
  小林英樹、羽根田破、大竹裕子、工藤祥司、土田孝之、芳山充晴、荒木勇雄
- Organizer
  The 43th Annual Meeting of International Continence Society
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-23592362
[Presentation] 膀胱上皮・排尿筋・末梢神経を標的にした下部尿路機能障害治療薬の開発2013
- Author(s)
  芳山充晴
- Organizer
  第20回日本排尿機能学会
- Place of Presentation
  静岡コンベンションアーツセンター、グランシップ（静岡県静岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Metabotropic glutamate receptor subtype 5 antagonist facilitates urine storage without impairing micturition in mice2013
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  San Diego Convention Center（San Diego, California, U.S.A）.
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Metabotropic Glutamate Receptor Subtype 5 Antagonist Facilitates Urinary Storage Without Impairing Micturition in Mice2013
- Author(s)
  Mitsuharu Yoshiyama, Sachiko Tsuchiya, Masayuki Takeda
- Organizer
  American Urological Association 2013 Annual meeting
- Place of Presentation
  San-Diego
- Data Source
  KAKENHI-PROJECT-23390381
[Presentation] Metabortopic glutamate receptor subtype 5 antagonist increases bladder capacity without impairing voiding in decerebrate unanesthetized mice2013
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  The 8th Pan=pacific Continence Society Meeting
- Place of Presentation
  BEXCO (Busan Exhibition & Convention Center)(Busan, Korea)
- Data Source
  KAKENHI-PROJECT-25462507
[Presentation] Vesicular nucleotide transporter (VNUT) is a key molecule for mechanosensing in the human urinary bladder: negative correlation between VNUT expression in human bladder mucosa and first desire to void. (Abstract No. 12)2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Kawahara K, Moriyama Y, Koizumi S, Takeda M.
- Organizer
  International Continence Society 42nd Annual meeting, China National Convention Centre
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] (vesicular nucleotide transporter) plays a crucial role in stretch-evoked ATP release from urothelium.2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Yoshiyama M, Araki I, Moriyama Y, Koizumi S, Takeda M.
- Organizer
  American Urological Association Annual Meeting, Georgia World Congress Center
- Place of Presentation
  Atlanta, Georgia, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] The functional role of EP4 receptors in the rat urinary bladder with outlet obstruction.2012
- Author(s)
  Zakoji H, Beppu M, Kobayashi H, Yoshiyama M, Takeda M, Araki I:
- Organizer
  European Association of Urology 27th Annual Congress, Paris, France
- Place of Presentation
  パリ
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Evaluation of increased voiding frequency in mice with type 2 diabetes mellitus2012
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  American Urological Association Annual Meeting, Georgia World Congress Center
- Place of Presentation
  Atlanta, Georgia, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 代謝型グルタミン酸受容体サブタイプ5を介する神経伝達の遮断は膀胱収縮性及び排尿を損ねずに蓄尿を促す2012
- Author(s)
  芳山充晴、土屋幸子、望月勉、中込宙史、宮本達也、吉良聡、武田正之
- Organizer
  第19回日本排尿機能学会
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Blockade of neural transmission via metabotropic glutamate receptor subtype 5 facilitates urine storage without impairing bladder contractility and micturition in mice(Abstract No. 133)2012
- Author(s)
  Yoshiyama M, Tsuchiya S, Takeda M.
- Organizer
  International Continence Society 42ndAnnual meeting, China National Convention Centre
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Risk factors of nocturia and assessment of nocturia-related quality of life in Japanese population.2011
- Author(s)
  Imamura N, Yoda Y, Nakagomi H, Miyamoto T, Tsuchida T, Fukazawa M, Araki I, Yoshiyama M, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Evaluations of increased voiding frequency in mice with diabetes mellitus at early stage2011
- Author(s)
  Yoshiyama, M., et al
- Organizer
  International Continence Society 41^<st> Annual Meeting
- Place of Presentation
  ScotishExhibition&conference Center (Glasgow, U.K.)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Comparisons between voluntary behaviour and reflex response in control of the lower urinary tract function of mice2011
- Author(s)
  Yoshiyama, M., et al
- Organizer
  International Continence Society 41^<st> Annual Meeting
- Place of Presentation
  ScotishExhibition&conference Center (Glasgow, U.K.)
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] VNUT plays an important role in vesicular storage and subsequent exocytosis of ATP from bladder epithelium upon mechanical stretch stimulation.2011
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Araki I, Koizumi S, Moriyama Y, Takeda M
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 遺伝性発症2型糖尿病マウスの若年期における頻尿の病態解析2011
- Author(s)
  芳山充晴, 他
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  ホテルフジタ福井(福井県福井市)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Comparisons between voluntary behaviour and reflex response in control of the lower urinary tract function of mice.2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Kobayashi H, Miyamoto T, Zakoji H, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Evalutations of increased voiding frequency in mice with diabetes mellitus at early stage.2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Kobayashi H, Zakoji H, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] TRPV4-deficient mice exhibit increased frequency of voiding ~evaluation of micturition behaviour using novel metabolic cage system~.2011
- Author(s)
  Mochizuki T, Yoshiyama M, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Intravesical infusion of anon-amiloride blocker of acid-sensing ion channels fails to affect lower urinary tract activity in unanesthetized decerebrate mice.2010
- Author(s)
  Yoshiyama M, et al.
- Organizer
  International Continence Society/International Uro-Gy necology Association Joint Meeting
- Place of Presentation
  Toronto,Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures using original culture cell stretch system2010
- Author(s)
  Mochizuki T, Nakagomi H, Miyamoto T, Araki I, Yoshiyama M, Takeda M
- Organizer
  American Urological Association 105th annual meeting, San Francisco
- Place of Presentation
  CA, USA
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Intravesical infusion of a non-amiloride blocker of acid-sensing ion channels fails to affect lower urinary tract activity in unanesthetized decerebrate mice2010
- Author(s)
  Yoshiyama M, Araki I, Kobayashi H, Zakoji H, Takeda M.
- Organizer
  International Continence Society 40th/International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Sex difference in expression profiles of acid-sensing ion channels and transient receptor potential channel v1 in the mouse urinary bladder2010
- Author(s)
  Kobayashi H, Yoshiyama M, Araki I, Kira S, Inuzuka H, Nakagomi H, Miyamoto T, Haneda Y, Sawada N, Kamiyama M, Kudou S, Zakoji H, Tsuchida T, Fukasawa M, Takeda M
- Organizer
  European Association of Urology 25th Annual Congress
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] The TRPV4 cation channel mediates stretchi-evoked CA2^+ influx and ATP release in primary urothelial cell cultures using original culture cell stretch system2010
- Author(s)
  Tsutomu Mochizuki, Hiroshi Nakagomi, Tatsuya Miyamoto, Isao Araki, Mitsuharu Yoshiyama, Masayuki Takeda
- Organizer
  AUA 2010
- Place of Presentation
  U.S.A.
- Year and Date
  2010-05-30
- Data Source
  KAKENHI-PROJECT-20390423
[Presentation] Gene expression patterns of acid-sensing ion channels (ASICs) families in mammalian bladder2010
- Author(s)
  Kobayashi H, Yoshiyama M, Inuzuka H, Kira S, Nakagomi H, Miyamoto T, Haneda Y, Sawada N, Zakoji H, Tsuchida T, Araki I, Takeda M
- Organizer
  International Continence Society 40th Annual Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Gene expression patterns of acid-sensing ion channels (ASICs) families in mammalian bladder.2010
- Author(s)
  Kobayashi H, Yoshiyama M, Inuzuka H, Kira S, Nakagomi H, Miyamoto T, Haneda Y, Sawada N, Zakoji H, Tsuchida T, Araki I, Takeda M.
- Organizer
  International Continence Society 40th/International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Hypertension and type 2 diabetes mellitus are highly associated with nocturia than metabolic syndrome in Japanese population.2010
- Author(s)
  Imamura N, Nakagomi H, Yoda Y, Zakoji H, Kobayashi H, Tsuchida T, Fukazawa M, Yoshiyama M, Araki I, Takeda M.
- Organizer
  International Continence Society 40th /International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 下部尿路機能研究-私の歴史2010
- Author(s)
  芳山充晴
- Organizer
  第17回日本排尿機能学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Intravesical infusion of a non-amiloride blocker of acid-sensing ion channels fails to affect lower urinary tract activity in unanesthetized decerebrate mice2010
- Author(s)
  Yoshiyama M, Araki I, Kobayashi H, Zakoji H, Takeda M
- Organizer
  International Continence Society 40th Annual Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] 除脳無麻酔マウスの下部尿路活動に対するAcid-Sensing Ion Channels(ASICs)阻害薬膀胱内注入の効果.2010
- Author(s)
  芳山充晴, 等
- Organizer
  第17回日本排尿機能学会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] The expression of transient receptor potential (TRP) V4, A1 and V1 in the human bladder mucosa of normal and bladder outlet obstruction: a novel mechanism in the obstruction-induced bladder overactivity2009
- Author(s)
  Miyamoto T, Mochizuki T, Zakoji H, Kobayashi H, Yoshiyama M, Araki I, Takeda M
- Organizer
  International Continence Society 39th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Effect of intravesical infusion of capsazepine, a TRPV1 blocker, on activity of the lower urinary tract irritated by acetic acid in unanesthetized decerebrate mice2009
- Author(s)
  Yoshiyama M, Kobayashi H, Araki I, Zakoji H, Takeda M
- Organizer
  International Continence Society 39th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Sex difference in expression profile of acid-sensing ion channels and transient receptor potential channel V1 in the mouse urinary bladder2009
- Author(s)
  Kobayashi H, Yoshiyama M, Araki I, Sawada N, Mochizuki T, Zakoji H, Takeda M
- Organizer
  International Continence Society 39th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21592068
[Presentation] Effects of a metabotropic glutamate receptor subtype 5 antagonist on lower urinary tract functions in mice with normal or transected spinal cords2008
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  International Continence Society 38^<th> Annual Meeting
- Place of Presentation
  Cairo, Egypt
- Year and Date
  2008-10-22
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Thr expression of prostaglandin E2 receptors (EP1, 2, 3, and 4) in the human urinary bladder epithelium of normal and bladder outlet obstruction - a novel mechanism in the afferent hyperactivity of bladder2008
- Author(s)
  Yuanjun, J. Kobayashi, H., Sawada, N., Yoshiyama, M., Mochizuki, T., Zakoji, H., Araki, I., and Takeda, M.
- Organizer
  American Urological Association
- Place of Presentation
  Orlando, Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Effects of a metabotropic glutamate receptor subtype 5 antagonist on lower urinary tract functions in mice with normal or transected spinal cords2008
- Author(s)
  Yoshiyama, M., Araki, I., Kobayashi, H., Zakoji, H., and Takeda, M.
- Organizer
  International Continence Society 38th Annual Meeting
- Place of Presentation
  Cairo, Egypt
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Involvements of metabotropic glutamate receptor subtype 5 (mGluR5) in control of lower urinary tract in mice with normal or transected spinal cords2008
- Author(s)
  Yoshiyama, M., Araki, I., Kobayashi, H., Zakoji, H., and Takeda, M.
- Organizer
  The 3rd Pan-Pacific Continence Society Meeting
- Place of Presentation
  Kaohsiung, Taiwan
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Contribution of acid-sensing ion channels to gender difference in mouse bladder response to acetic acid : a novel candidate for interstitial cystitis pathogenesis2008
- Author(s)
  Kobayashi, H., Yoshiyama, M., Araki, I., Zakoji, H., Sawada, N., Mochizuki, T., Tsuchida, T., Nomura, T., Fukasawa, M., and Takeda, M.
- Organizer
  American Urological Association May
- Place of Presentation
  Orlando, Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] The expression of prostaglandin E2 receptors (EP1, 2, 3, and 4) in the human bladder epithelium of normal and bladder outlet obstruction. -a novel mechanism in the afferent hyperactivity of bladder.2008
- Author(s)
  Yuanjun J, Kobayashj H, Sawada N, Yoshiyama M, Mochizuki T, Zakoji H, Araki I, Takeda M.
- Organizer
  The 103^<rd> Annual Meeting of The American Urological Association.
- Place of Presentation
  Orland, USA
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20390423
[Presentation] マウス下部尿路機能に対する代謝型グルタミン酸受容体サブタイプ5拮抗薬の作用 : 脊髄正常群と慢性脊髄損傷群の比較2008
- Author(s)
  芳山充晴
- Organizer
  第15回日本排尿機能学会. 大手町サンケイプラザ
- Place of Presentation
  東京
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] The expression of prostaglandin E2 receptors (EP1, 2, 3, and 4) in the human urinary bladder epithelium of normal and bladder outlet obstruction.2008
- Author(s)
  Jiang Yuan Jun, Hideki Kobayashi, Norifumi SAWADA, Mitsuharu Yoshiyama, Tsutomu Mochizuki, Hidenori Zakoji, Isao Araki, Masayuki Takeda
- Organizer
  -A novel mechanism in the E10afferent hyperactivity of bladder-,AUA2008
- Place of Presentation
  U.S.A.
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20390423
[Presentation] Contribution of acid-sensing ion channels to gender difference in mouse bladder response to acetic acid : a novel candidate for interstitial cystitis pathogenesis.2008
- Author(s)
  Kobayashi H, Yoshiyama M, Araki I, Zakoji H, Sawada N, Mochizuki T, Tsuchuida T, Nomura T, Fukasawa M, Takeda M.
- Organizer
  The 103^<rd> Annual Meeting of The American Urological Association.
- Place of Presentation
  Orland, USA
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20390423
[Presentation] マウス下部尿路機能に対する代謝型グルタミン酸受容体サブタイプ5拮抗薬の作用 : 脊髄正常群と慢性脊髄損傷群の比較2008
- Author(s)
  芳山充晴
- Organizer
  第15回日本排尿機能学会
- Place of Presentation
  大手町サンケイプラザ、東京
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Different cystometric responses between male and female mice to the lower urinary tract irritation by acetic acid2007
- Author(s)
  Yoshiyama, M., Araki, I., Kobayashi, H., Zakoji, H., Du, S., and Takeda, M.
- Organizer
  International Continence Society 37^<th> Annual Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Role of metabotropic glutamate receptor subtype 1 in afferent processing of reflex micturition in mice2007
- Author(s)
  Yoshiyama, M., Araki, I., Zakoji, H. Kobayashi, H., Du, S., Aiba, A., and Takeda, M.
- Organizer
  American Urological Association
- Place of Presentation
  Anaheim, California, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Additive control by metabotropic glutamate receptors 1 and 5 in bladder afferent mechanosensory transmission.2007
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  International Continence Society 37th Annual Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Year and Date
  2007-08-22
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Additive control by metabotropic glutamate receptors 1 and 5 in bladder afferent mechanosensory transmission2007
- Author(s)
  Yoshiyama, M., Araki, I., Zakoji, H., Kobayashi, H., Du, S., Aiba, A., and Takeda, M.
- Organizer
  International Continence Society 37^<th> Annual Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] The expression and role of large conductance, voltage- and Ca^<2+>-activated K^+ (BK) channels in the urinary bladder : the alteration of subunit expression profile in association with bladder outlet obstruction, and the affect of BK channel on the afferent ex2007
- Author(s)
  Zakoji, H., Araki, I., Beppu, M., Yoshiyama, M., Kobayashi, H., Du, S., Sawada, N., Mochizuki, T., Fukasawa, M., Takihana, Y., and Takeda, M.
- Organizer
  American Urological Association
- Place of Presentation
  Anaheim, California, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Photo-stimulating effects of low reactive level laser on micturition function in rats2007
- Author(s)
  Uchiyama, T., Sakakibara, R., Yoshiyama, M., Lui, Z., Yamamoto, T., Ito, T., Yamaguchi, C, Awa, Y., Yamanishi, T., and Hattori, T.
- Organizer
  International Continence Society 37^<th> Annual Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Agonists of transient receptor potential channel A1 cause hyper-reflexic micturition by affecting bladder afferent activity in rats2007
- Author(s)
  Du, S., Araki, I., Nomura, T., Yoshiyama, M., and Takeda, M.
- Organizer
  American Urological Association
- Place of Presentation
  Anaheim, California, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Role of metabotropic glutamate receptor subtype 1 in afferent processing of reflex micturition in mice.2007
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  American Urological Association
- Place of Presentation
  Anaheim, California, USA
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] The expression and the role of BK channels in the urinary bladder : the alteration of subunit expression profile in association with bladder outlet obstruction, and the affect of BK channel on afferent pathway in lower urinary tract2007
- Author(s)
  Zakoji, H., Araki, I., Beppu, M., Yoshiyama, M., Du, S., Kobayashi, H., Mochizuki, T., and Takeda, M.
- Organizer
  International Continence Society 37^<th> Annual Meeting, Rotterdam
- Place of Presentation
  The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] 膀胱求心路の機械的知覚伝達における代謝型グルタミン酸受容体サブタイプmGluR1とmGluR5を介する相加的コントロール2007
- Author(s)
  芳山充晴
- Organizer
  第14回日本排尿機能学会
- Place of Presentation
  福島県ホテルリステル猪苗代
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Acid-sensing ion channel : expression changes in the urinary bladder following chronic bladder inflammation2007
- Author(s)
  Kobayashi, H., Araki, I., Zakoji, H., Du, S., Sawada, N., Mochizuki, T., Yoshiyama, M., Tsuchida, T., Nomura, T., Fukasawa, M., Takihana, Y., and Takeda, M.
- Organizer
  International Continence Society 37^<th> Annual Meeting, Rotterdam
- Place of Presentation
  The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Irradiation induces detrusor overactivity studied acutely using a mouse model of radiation cystitis2007
- Author(s)
  Zabbarova, I., Roppolo, J., Yoshiyama, M., Ikeda, Y., McCarthy, C., Hagedorn, N., Birder, L., Fry, C., de Groat, W., and Kanai, A
- Organizer
  International Continence Society 37^<th> Annual Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Amiloride-sensitive ion channels in urinary bladder epithelium involved in mechanosensory transduction by modulating stretch-evoked ATP release2007
- Author(s)
  Du, S., Araki, I., Mikami, Y., Yoshiyama, M., and Takeda, M.
- Organizer
  American Urological Association
- Place of Presentation
  Anaheim, California, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] 膀胱求心路の機械的知覚伝達における代謝型グルタミン酸受容体サブタイプmGluR1とmGluR5を介する相加的コントロール2007
- Author(s)
  芳山充晴
- Organizer
  第14回日本排尿機能学会
- Place of Presentation
  福島県ホテルリステル猪苗代
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19591839
[Presentation] Blockade of neural transmission via metabotropic glutamate receptor subtype 5 facilitates urine storage without impairing bladder contractility and micturition in mice
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  International Continence Society 42nd Annualmeeting
- Place of Presentation
  China National Convention Centre(Beijing, China)
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 代謝型グルタミン酸受容体サブタイプ5を介する神経伝達の遮断は膀胱収縮性及び排尿を損ねずに蓄尿を促す
- Author(s)
  芳山充晴
- Organizer
  第19回日本排尿機能学会
- Place of Presentation
  名古屋国際会議場(名古屋市）
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Evaluation of increased voiding frequency in mice with type 2 diabetes mellitus
- Author(s)
  Mitsuharu Yoshiyama
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  Georgia World Congress Center(Atlanta, Georgia, U.S.A.)
- Data Source
  KAKENHI-PROJECT-22591787

1. TAKEDA Masayuki (80197318)

# of Collaborated Projects: 8 results

# of Collaborated Products: 29 results
2. KOBAYASHI Hideki (50402053)

# of Collaborated Projects: 6 results

# of Collaborated Products: 33 results
3. MOCHIZUKI Tsutomu (50377496)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
4. NAKAGOMI Hiroshi (80418714)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
5. ARAKI Isao (50252424)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
6. TOMINAGA Makoto (90260041)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SAWADA Norifumi (70402055)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. KIRA Satoru (10530115)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
9. ZAKOUJI Hidenori (60345717)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. TSUCHIDA Takayuki (30217327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. KOIZUMI Syuichi (10280752)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
12. MIYAMOTO Tatsuya (80456459)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. NAKAHASHI JYUNKO (20468226)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. IGUTI KUMIKO (20582109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NISHIMURA AKIKO (30436886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. NISHIZAWA MIYOKO (40446183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. IHARA Tatsuya (90622407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
18. FUKASAWA Mizuya (80252039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. TSURU Teruhiko (90625675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KOBAYASHI TATSUKO (10279896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAKAMURA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. SHIGETOMI Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 中尾篤人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 三井貴彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

YOSHIYAMA Mitsuharu 芳山 充晴

Research Projects

Research Products

Co-Researchers

Analysis of action of neurotrophic factor precursor via glutamatergic signal transmission that is involved in voiding dysfunction after spinal cord injuryPrincipal Investigator

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Functional analysis of the metabotropic glutamate receptor and the acid-sensitive ion channels as a urine collection control moleculePrincipal Investigator

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Studies on lower urinary tract dysfunction pathogenesis by complex systems network and dynamic homeostasis collapse

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Plastic changes in transmission of neuropeptide and metabotropic glutamate related to voiding dysfunction after chronic spinal cord injuryPrincipal Investigator

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Effects of evening foot bathing on older adults with night nocturia for night urination status and sleep status

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Research on the afferent transduction in the lower urinary tract

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Involvements of TRPV1 and TRPV4 channels in regulatory function to maintain bladder stability during urine storage: integrated analysis of behavior and reflex

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The mechanism of action of aconite and botulinum toxin for interstitial cystitis pain

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Strategy targeting neuropeptide receptors in the central and peripheral nervous systems in treatment of underactive bladderPrincipal Investigator

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Contribution of acid-sensing nociceptor molecules (ASIC and TRPV1) to symptom onset in interstitial cystitis

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Reseaarch on the function and development of new therapy for Ion channels in the lower urinary tract

Principal Investigator

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Elucidation of pathophysiology in voiding dysfunction after spinal cord injury and its treatments : a study on functional roles of spinal metabotropic glutamatergic mechanismPrincipal Investigator

Principal Investigator

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Research Institution

[Book] Handbook of Neurourology: Theory and Practice2023

Author(s)

Total Pages

Publisher

YOSHIYAMA Mitsuharu 芳山充晴