Makino Takamitsu 牧野貴充

Researcher Number	20433039
Other IDs
Affiliation (based on the past Project Information) *help	2015: 熊本大学, その他の研究科, 講師 2015: 熊本大学, 大学院生命科学研究部, 講師 2014: 熊本大学, 生命科学研究部, 講師 2013: 熊本大学, 生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Dermatology
Keywords	Principal Investigator mRNA / 免疫抑制剤 / リンパ球 / サイトカイン / 全身性強皮症

The mechanism of immunosuppressive treatment in systemic sclerosis.Principal Investigator
- Principal Investigator
  
  Makino Takamitsu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Kumamoto University

All 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Serum concentrations of Flt-3 ligand in rheumatic diseases2015
- Author(s)
  Nakamura K, Nakatsuka N, Jinnin M, Makino T, Kajihara I, Makino K, Honda N, Inoue K, Fukushima S, Ihn H.
- Journal Title
  
  BioScience Trends
  
  Volume: 9 Issue: 5 Pages: 342-349
- DOI
  10.5582/bst.2015.01121
- NAID
  130005109609
- ISSN
  1881-7815, 1881-7823
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09772, KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-26860886
[Journal Article] Mice overexpressing integrin αv in fibroblasts exhibit dermal thinning of the skin.2015
- Author(s)
  Wang Z, Jinnin M, Kobayashi Y, Kudo H, Inoue K, Nakayama W, Honda N, Makino K, Kajihara I, Makino T, Fukushima S, Inagaki Y, Ihn H.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 79 Issue: 3 Pages: 268-278
- DOI
  10.1016/j.jdermsci.2015.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09772, KAKENHI-PROJECT-15K15299, KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-26860886, KAKENHI-PROJECT-25293179
[Journal Article] EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.2015
- Author(s)
  Kudo H, Wang Z, Jinnin M, Nakayama W, Inoue K, Honda N, Nakashima T, Kajihara I, Makino K, Makino T, Fukushima S, Ihn H.
- Journal Title
  
  J Immunol.
  
  Volume: 195 Issue: 8 Pages: 3565-3573
- DOI
  10.4049/jimmunol.1402362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09772, KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-26860886
[Journal Article] Enhanced CCR9 expression levels in psoriatic skin are associated with poor clinical outcome to infliximab treatment.2015
- Author(s)
  Koga A, Kajihara I, Yamada S, Makino K, Ichihara A, Aoi J, Makino T, Fukushima S, Jinnin M, Ihn H.
- Journal Title
  
  J Dermatol.
  
  Volume: 43 Issue: 5 Pages: 522-5
- DOI
  10.1111/1346-8138.13178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-15K09772, KAKENHI-PROJECT-16K19728
[Journal Article] Down-regulation of microRNA-196a in the sera and involved skin of localized scleroderma patients2014
- Author(s)
  Takamitsu Makino; Masatoshi Jinnin; Mitsuhiko Etoh; Keitaro Yamane; Ikko Kajihara; Katsunari Makino; Asako Ichihara; Toshikatsu Igata; Keisuke Sakai; Satoshi Fukushima;
- Journal Title
  
  European Journal of Dermatology
  
  Volume: 24(4) Issue: 4 Pages: 760-6
- DOI
  10.1684/ejd.2014.2384
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-25860956, KAKENHI-PROJECT-25870545, KAKENHI-PROJECT-25870555
[Journal Article] Proportion of Lymphocytic Inflammation with CD123 Positive Cells in Lupus Erythematous Profundus Predict a Clinical Response to Treatment.2013
- Author(s)
  Miyashita A, Fukushima S, Makino T, Yoshino Y, Yamashita J, Honda N, Aoi J, Ichihara A, Jinnin M, Inoue Y, Ihn H.
- Journal Title
  
  Acta Dermato-Venereologica
  
  Volume: 17 Issue: 5 Pages: 563-567
- DOI
  10.2340/00015555-1777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-25860956, KAKENHI-PROJECT-25870545, KAKENHI-PROJECT-25870554
[Journal Article] Down-regulation of miR-223 contributes to the formation of Gottron's papules in dermatomyositis via the induction of PKCε2013
- Author(s)
  Inoue K, Jinnin M, Yamane K, Makino T, Kajihara I, Makino K, Honda N, Nakayama W, Fukushima S, Ihn H.
- Journal Title
  
  European Journel of Dermatology
  
  Volume: 23 Issue: 2 Pages: 160-167
- DOI
  10.1684/ejd.2013.1959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-25870545
[Journal Article] Serum levels of tenascin-C in collagen diseases.2013
- Author(s)
  Inoue K, Jinnin M, Hara Y, Makino K, Kajihara I, Makino T, Sakai K, Fukushima S, Inoue Y, Ihn H.
- Journal Title
  
  Journal of Dermatology
  
  Volume: 40 Pages: 715-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955
[Journal Article] MIRSNP rs2910164 of miR-146a is associated with the muscle involvement in polymyositis/dermatomyositis.2013
- Author(s)
  Okada Y, Jinnin M, Makino T, Kajihara I, Makino K, Honda N, Nakayama W, Inoue K, Fukushima S, Ihn H.
- Journal Title
  
  International Journal of Dermatology
  
  Volume: 53 Pages: 300-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955
[Journal Article] The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma.2013
- Author(s)
  Makino K, Jinnin M, Hirano A, Yamane K, Eto M, Kusano T, Honda N, Kajihara I, Makino T, Sakai K, Masuguchi S, Fukushima S, Ihn H.
- Journal Title
  
  Journal of Immunology
  
  Volume: 190 Issue: 8 Pages: 3905-3915
- DOI
  10.4049/jimmunol.1200822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-25870545, KAKENHI-PROJECT-25870555
[Journal Article] Expression analysis of multiple microRNAs in each patient with scleroderma.2013
- Author(s)
  Koba S, Jinnin M, Inoue K, Nakayama W, Honda N, Makino K, Kajihara I, Makino T, Fukushima S, Ihn H.
- Journal Title
  
  Experimental Dermatology
  
  Volume: 22 Issue: 7 Pages: 489-491
- DOI
  10.1111/exd.12173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860955, KAKENHI-PROJECT-25870545, KAKENHI-PROJECT-25870555
[Presentation] Increased CD27 expression in the skin and sera of the patients with systemic sclerosis.2016
- Author(s)
  Takamitsu Makino, Masatoshi Jinnin, Miri Nakayama, Satoshi Fukushima, Shinichi Masuguchi, Hironobu Ihn
- Organizer
  4th Systemic Sclerosis World Congress
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860955
[Presentation] 限局性強皮症における血清および皮膚組織中miR-196aの発現低下とⅠ型コラーゲン蛋白合成の関連2015
- Author(s)
  牧野貴充、神人正寿、江藤光彦、山根惠太郎、梶原一亨、牧野雄成、福島　聡、尹　浩信
- Organizer
  第47回日本結合組織学会
- Place of Presentation
  東京
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25860955
[Presentation] Effects of Sarpogrelate hydrochloride for Raynaud’s phenomenon secondary to systemic sclerosis2014
- Author(s)
  Takamitsu Makino, Masatoshi Jinnin, Ikkou Kajihara, Katsunari Makino, Hironobu Ihn
- Organizer
  3rd Systemic sclerosis World Congress
- Place of Presentation
  Rome
- Data Source
  KAKENHI-PROJECT-25860955
[Presentation] 限局性強皮症における血清および皮膚組織中miR-196aの発現低下と線維化機序の関連
- Author(s)
  牧野貴充、神人正寿、江藤光彦、山根惠太郎、梶原一亨、牧野雄成、福島　聡、尹　浩信
- Organizer
  第42回臨床免疫学会
- Place of Presentation
  東京
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860955

1. JINNIN Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. FUKUSHIMA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 尹浩信

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Makino Takamitsu 牧野 貴充

Research Projects

Research Products

Co-Researchers

The mechanism of immunosuppressive treatment in systemic sclerosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Serum concentrations of Flt-3 ligand in rheumatic diseases2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Mice overexpressing integrin αv in fibroblasts exhibit dermal thinning of the skin.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced CCR9 expression levels in psoriatic skin are associated with poor clinical outcome to infliximab treatment.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Down-regulation of microRNA-196a in the sera and involved skin of localized scleroderma patients2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proportion of Lymphocytic Inflammation with CD123 Positive Cells in Lupus Erythematous Profundus Predict a Clinical Response to Treatment.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Down-regulation of miR-223 contributes to the formation of Gottron's papules in dermatomyositis via the induction of PKCε2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum levels of tenascin-C in collagen diseases.2013

Author(s)

Journal Title

Data Source

[Journal Article] MIRSNP rs2910164 of miR-146a is associated with the muscle involvement in polymyositis/dermatomyositis.2013

Author(s)

Journal Title

Data Source

[Journal Article] The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analysis of multiple microRNAs in each patient with scleroderma.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Increased CD27 expression in the skin and sera of the patients with systemic sclerosis.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 限局性強皮症における血清および皮膚組織中miR-196aの発現低下とⅠ型コラーゲン蛋白合成の関連2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Effects of Sarpogrelate hydrochloride for Raynaud’s phenomenon secondary to systemic sclerosis2014

Author(s)

Makino Takamitsu 牧野貴充