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Torisu kumiko  鳥巣 久美子

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Torisu Kumiko  鳥巣 久美子

鳥巣 久美子  トリス クミコ

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Researcher Number 20448434
Other IDs
Affiliation (Current) 2025: 九州大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help 2025: 九州大学, 医学研究院, 准教授
2017 – 2023: 九州大学, 医学研究院, 准教授
2015 – 2016: 九州大学, 大学病院, 助教
2014: 九州大学, 大学病院, その他
2009: Kyushu University, 生体防御医学研究所, (非常勤研究員)
2008 – 2009: Kyushu University, 生体防御医学研究所, 非常勤研究員
Review Section/Research Field
Principal Investigator
Basic Section 53040:Nephrology-related / Kidney internal medicine / Circulatory organs internal medicine
Except Principal Investigator
Basic Section 53040:Nephrology-related / Basic Section 48020:Physiology-related
Keywords
Principal Investigator
スペルミジン / アルギニン代謝 / 近位尿細管 / アルギニン / アルギナーゼ / オートファジー / 腎障害 / 抗加齢因子 / 慢性腎障害 / 活性酸素ストレス … More / 腎線維化 / ポリアミン / 慢性腎臓病 / 腎臓線維化 / 酸化ストレス / 一酸化窒素 / Arginase 2 / 虚血再灌流 / アルギナーゼ2 / 尿細管細胞 / 活性酸素 / 腎虚血再灌流 / 虚血再灌流障害 / 急性腎障害 / ニトロ化ストレス / Carciprotein particle / 平滑筋細胞 / 血管平滑筋細胞 / Calciprotein particle / 血管石灰化 / 腎不全 / 循環器、高血圧 / マウス / DNA損傷 / 動脈硬化 / 分子血管病態学 … More
Except Principal Investigator
慢性腎臓病 / CPP / 血管石灰化 / 腹膜透析 / 栄養障害 / インターロイキン / 炎症 / 被嚢性腹膜硬化症 / りん / マグネシウム / リン / 腹膜石灰化 / 腹膜透析療法 / 心筋肥大 / 芳香族炭化水素受容体 / 左室肥大 / FGF23 / インドキシル硫酸 / メタゲノム解析 / 腸腎連関 / 腎移植 / CKD / メタゲノム / 腸内細菌 / 骨格筋骨相関 / 骨格筋量 / 慢性腎不全 / マイオカイン / XPR1 / 骨格筋 / 骨格筋血管相関 / 骨血管相関 / 骨粗鬆症 / サルコペニア / 認知機能障害 / トレイルメイキングテスト / 遂行機能 / 前頭葉機能 / 脳灰白質容積 / MRI / 脳萎縮 / 血液透析 Less
  • Research Projects

    (11 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (13 People)
  •  CPPによる慢性炎症とCKD関連多臓器障害の病態機序解明および治療法の確立

    • Principal Investigator
      山田 俊輔
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  Anti-aging factor spermidine protects the kidneys and the whole bodyPrincipal Investigator

    • Principal Investigator
      鳥巣 久美子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  腹膜透析による腹膜線維化と石灰化の病態解明~リンの関与とマグネシウムの競合作用

    • Principal Investigator
      山田 俊輔
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  Gut-kidney axis: Microbiota and bacterial-derived metabolites affect chronic kidney disease.

    • Principal Investigator
      Torisu Takehiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Kyushu University
  •  The mechanism of left ventricular hypertrophy in CKD

    • Principal Investigator
      Nakano Toshiaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  Arginine metabolism and autophagy, elucidation of mitochondrial protection mechanism in kidneyPrincipal Investigator

    • Principal Investigator
      TORISU KUMIKO
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  Treatment for vascular calcification by focusing on the interplay among blood vessel/heart, bone, and skeletal muscle

    • Principal Investigator
      Yamada Shunsuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyushu University
  •  Longitudinal cohort study of cognitive impairment and atherosclerosis in geriatric patients with chronic kidney disease

    • Principal Investigator
      Tsuruya Kazuhiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Nara Medical University
  •  The role and regulatory mechanism of arginase 2 for acute kidney injuryPrincipal Investigator

    • Principal Investigator
      TORISU KUMIKO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyushu University
  •  Can autophagy attenuate vascular calcification?Principal Investigator

    • Principal Investigator
      Torisu Kumiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyushu University
  •  Oxidative DNA damage and its defense mechanism in atherosclerosisPrincipal Investigator

    • Principal Investigator
      鳥巣 久美子
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University

All 2023 2022 2021 2020 2019 2018 2017 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Gastroduodenal Ulcers in Liver Transplant Recipients under Immunosuppressive Therapy2023

    • Author(s)
      Kakizoe Kozue、Torisu Takehiro、Ihara Yutaro、Harada Noboru、Yoshizumi Tomoharu、Fujioka Shin、Kondo Masahiro、Kitazono Takanari
    • Journal Title

      Digestive Diseases

      Volume: 41 Issue: 4 Pages: 565-571

    • DOI

      10.1159/000530472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06783
  • [Journal Article] Magnesium inhibits peritoneal calcification as a late-stage characteristic of encapsulating peritoneal sclerosis2023

    • Author(s)
      Aihara Seishi、Yamada Shunsuke、Matsueda Shumei、Nagashima Akinori、Torisu Kumiko、Kitazono Takanari、Nakano Toshiaki
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 16340-16340

    • DOI

      10.1038/s41598-023-43657-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08355
  • [Journal Article] Clinical Features of Gastroduodenal Ulcers in Kidney Transplant Patients2023

    • Author(s)
      Kondo Masahiro、Torisu Takehiro、Ihara Yutaro、Kawasaki Keisuke、Umeno Junji、Kawatoko Shinichiro、Tsuchimoto Akihiro、Nakano Toshiaki、Okabe Yasuhiro、Kitazono Takanari
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 23 Pages: 3437-3443

    • DOI

      10.2169/internalmedicine.1508-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-12-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06783
  • [Journal Article] Duodenal microbiome in chronic kidney disease2023

    • Author(s)
      Kondo Masahiro、Torisu Takehiro、Nagasue Tomohiro、Shibata Hiroki、Umeno Junji、Kawasaki Keisuke、Fujioka Shin、Matsuno Yuichi、Moriyama Tomohiko、Kitazono Takanari
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 28 Issue: 4 Pages: 263-272

    • DOI

      10.1007/s10157-023-02434-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06783
  • [Journal Article] Indoxyl sulfate induces left ventricular hypertrophy via the AhR-FGF23-FGFR4 signaling pathway2023

    • Author(s)
      Kishimoto Hiroshi、Nakano Toshiaki、Torisu Kumiko、Tokumoto Masanori、Uchida Yushi、Yamada Shunsuke、Taniguchi Masatomo、Kitazono Takanari
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 10 Pages: 990422-990422

    • DOI

      10.3389/fcvm.2023.990422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08232
  • [Journal Article] Protective Roles of Xenotropic and Polytropic Retrovirus Receptor 1 (XPR1) in Uremic Vascular Calcification2022

    • Author(s)
      Arase H, Yamada S, Torisu K, Tokumoto M, Taniguchi M, Tsuruya K, Nakano T, Kitazono T
    • Journal Title

      Calcified Tissue International and Musculoskeletal Research

      Volume: - Issue: 6 Pages: 685-697

    • DOI

      10.1007/s00223-022-00947-3

    • Data Source
      KAKENHI-PROJECT-19K08706
  • [Journal Article] The Compositional Structure of the Small Intestinal Microbial Community via Balloon-Assisted Enteroscopy2022

    • Author(s)
      Nagasue T, Hirano A, Torisu T, Umeno J, Shibata H, Moriyama T, Kawasaki K, Fujioka S, Fuyuno Y, Matsuno Y, Esaki M, Kitazono T
    • Journal Title

      Digestion

      Volume: - Issue: 4 Pages: 1-11

    • DOI

      10.1159/000524023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K22929, KAKENHI-PROJECT-21K06783, KAKENHI-PROJECT-22K15668
  • [Journal Article] Arginase 2 is a mediator of ischemia-reperfusion injury in the kidney through regulation of nitrosative stress2020

    • Author(s)
      Hara M, Torisu K, Tomita K, Kawai Y, Tsuruya K, Nakano T, Kitazono T
    • Journal Title

      Kidney International

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09701
  • [Presentation] 上部良性消化管疾患における最新の内視鏡診断と治療 臓器移植レシピエントにおける消化性潰瘍2023

    • Author(s)
      鳥巣 剛弘(九州大学 病態機能内科), 井原 勇太郎, 近藤 雅浩
    • Organizer
      日本消化器病学会大会(ワークショップ)
    • Data Source
      KAKENHI-PROJECT-21K06783
  • [Presentation] Arginine metabolism regulates the transcription factor Nrf2 and prevents renal interstitial fibrosis through tubular spermidine production2022

    • Author(s)
      Seishi Aihara, Kumiko Torisu, Toshiaki Nakano, Takanari Kitazono
    • Organizer
      American Society of Nephrology, Kidney Week 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] アルギナーゼ2はスペルミジン産生を介して腎間質線維化を制御する2022

    • Author(s)
      相原成志、鳥巣久美子、中野敏昭、北園孝成
    • Organizer
      第65回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] アルギニン代謝とAKI2022

    • Author(s)
      鳥巣久美子、相原成志、原雅俊、中野敏昭、北園孝成
    • Organizer
      第65回日本腎臓学会学術総会シンポジウム「新規解析手法とTargetでAKIに挑む」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] Arginine metabolism regulates the transcription factor Nrf2 and prevents renal interstitial fibrosis.2022

    • Author(s)
      鳥巣 久美子
    • Organizer
      日本薬理学会
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] 腎臓線維化においてアルギニン代謝が亢進しスペルミジンがNrf2を活性化する2022

    • Author(s)
      鳥巣久美子、相原成志、中野敏昭
    • Organizer
      第52回西部腎臓学会シンポジウム「線維化、再生」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] アルギニン代謝は転写因子Nrf2を制御し腎臓間質線維化を抑制する2022

    • Author(s)
      鳥巣久美子、相原成志、中野敏昭、北園孝成
    • Organizer
      第95回日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] Arginine metabolism is activated in kidney fibrosis to produce spermidine, which acts in antifibrosis through induction of Nrf22022

    • Author(s)
      Torisu K, Aihara S, Nakano T
    • Organizer
      第45回日本分子生物学会年会ワークショップ「複雑な細胞構成をもつ腎臓を通して全身の病態を考える」
    • Data Source
      KAKENHI-PROJECT-20K08610
  • [Presentation] インドキシル硫酸はFGFR4・FGF23経路を介して心筋細胞の肥大を促進する.2021

    • Author(s)
      岸本啓志,中野敏昭,鳥巣久美子,山田俊輔,徳本正憲,谷口正智,北園孝成
    • Organizer
      第64回日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-21K08232
  • [Presentation] 当院における腎移植後患者に対する胃十二指腸潰瘍の臨床的検討2021

    • Author(s)
      近藤 雅浩, 鳥巣 剛弘, 柿添 梢, 井原 勇太郎, 土本 晃裕, 岡部 安博, 北園 孝成
    • Organizer
      118回日本消化器病学会 九州支部例会
    • Data Source
      KAKENHI-PROJECT-21K06783
  • [Presentation] C57BL/6マウスを用いた血管石灰化モデルの作製と尿毒症性血管石灰化におけるXPR1の役割の検討2021

    • Author(s)
      荒瀬北斗、山田俊輔、鳥巣久美子、徳本正憲、谷口正智、中野敏明、北園孝成
    • Organizer
      第64回日本腎臓学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-19K08706
  • [Presentation] C57BL/6マウスを用いた血管石灰化モデルの作製と尿毒症性血管石灰化におけるXPR1の役割の検討2021

    • Author(s)
      荒瀬北斗、山田俊輔、鳥巣久美子、徳本正憲、谷口正智、中野敏明、北園孝成
    • Organizer
      第5回日本CKD-MBD研究会
    • Data Source
      KAKENHI-PROJECT-19K08706
  • [Presentation] アルギナーゼ2はニトロ化ストレスを介した腎虚血再灌流障害を誘導する2019

    • Author(s)
      原雅俊、鳥巣久美子、川井康弘、鶴屋和彦、中野敏昭、北園孝成
    • Organizer
      第62回日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09701
  • [Presentation] アルギナーゼ2はニトロ化ストレスを介した腎虚血再灌流を誘導する2019

    • Author(s)
      原雅俊、鳥巣久美子、川井康弘、鶴屋和彦、中野敏明、北園孝成
    • Organizer
      第62回日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09701
  • [Presentation] Arginase 2 mediates ischemia-reperfusion injury in the kidney through regulation of nitrosative stress2018

    • Author(s)
      Hara M, Torisu K, Kawai Y, Nakano, T, Tsuruya K, Kitazono T
    • Organizer
      American Society of Nephrology, Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09701
  • [Presentation] 尿細管のアルギナーゼ2発現は虚血再灌流で増加する2017

    • Author(s)
      原雅俊、鳥巣久美子、川井康弘、四枝龍佑、長谷川祥子、鶴屋和彦、北園孝成
    • Organizer
      第60回日本腎臓学会総会
    • Data Source
      KAKENHI-PROJECT-17K09701
  • [Presentation] 脳梗塞感受性遺伝子Prkchの欠損はApoe遺伝子欠損マウスにおける高脂血症と動脈硬化を改善する2010

    • Author(s)
      鳥巣久美子、張学礼、野中麻里、中別府雄作
    • Organizer
      第2回Kyushu CVD Conference
    • Place of Presentation
      福岡
    • Year and Date
      2010-01-23
    • Data Source
      KAKENHI-PROJECT-20790535
  • [Presentation] Disruption of Prkch gene for protein kinase C η efficiently attenuates atherosclerosis in mice2009

    • Author(s)
      鳥巣久美子、張学礼、野中麻里、中別府雄作
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20790535
  • [Presentation] Disruption of Prkch gene for protein kinse Cηefficiently attenuates atherosclerosis in mice.2008

    • Author(s)
      鳥巣久美子、張学礼、野中麻里、中別府雄作
    • Organizer
      第32回分子生物学会年会
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-20790535
  • [Presentation] 脳梗塞感受性遺伝子であるPRKCHは動脈硬化の進展に関与するか?2008

    • Author(s)
      鳥巣久美子、張学礼、中別府雄作
    • Organizer
      九州CVDカンファレンス第一回研究会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-20790535
  • [Presentation] 脳梗塞感受性遺伝子であるPRKCHは動脈硬化の進展に関与するか2008

    • Author(s)
      鳥巣久美子、張学礼、中別府雄作
    • Organizer
      九州CVDカンファレンス第一回研究会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-20790535
  • 1.  Nakano Toshiaki (10432931)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 2.  Yamada Shunsuke (10419608)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 6 results
  • 3.  Tsuruya Kazuhiko (20372740)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 4.  升谷 耕介 (30419593)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  土本 晃裕 (50572103)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Torisu Takehiro (30453228)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  長谷川 祥子 (10626089)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  藤崎 毅一郎 (10444811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  江里口 雅裕 (40572102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  原 雅俊 (60626092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  梅野 淳嗣 (70621704)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  秋本 卓 (50816618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  松野 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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