Nakashima Kentaro 中島健太郎

… Alternative Names

中島健太郎ナカシマケンタロウ

NAKASHIMA Kentaro 中島健太郎

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Researcher Number	20449911
Other IDs
Affiliation (Current)	2025: 徳島文理大学, 神経科学研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 徳島文理大学, 神経科学研究所, 助教 2020 – 2022: 徳島文理大学, 神経科学研究所, 助教 2019: 徳島文理大学, 神経科学研究所, 助手 2016 – 2017: 徳島文理大学, 大学共同利用機関等の部局等, 助手 2014 – 2015: 徳島文理大学, 神経科学研究所, 助手 2011 – 2014: 徳島文理大学, 大学共同利用機関等の部局等, 助手
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Human pathology Except Principal Investigator Basic / Social brain science / Neuroscience in general
Keywords	Principal Investigator Remyelination / Demyelination / Multiple sclerosis / CYP51 / Cuprizone / 脱髄性疾患 / オリゴデンドロサイト / コレステロール / Lanosterol / LDM … More / 髄鞘再生 / 脱髄 / 多発性硬化症 / リアルタイムPCR / 遺伝子発現解析 / 免疫組織化学 / 分子病理学 / LCM / Laser Microdissection … More Except Principal Investigator 病態モデル / laser microdissection / 免疫組織化学 / シナプス / 樹状突起 / 病態モデルマウス / アルツハイマー病 / SCD / CO差還元 spectrum / 酵素活性 / SNP / 脂質代謝 / トランスジェニックマウス / proteolipid protein / 髄鞘 / cuprizone / 髄鞘再生 / 脱髄 / 髄鞘形成 / シュワン細胞 / オリゴデンドログリア / CYP51 / LDM Less

グリア細胞の協調的コレステロール代謝制御による髄鞘再生促進の分子基盤の解明Principal Investigator
- Principal Investigator
  
  中島健太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokushima Bunri University
The Search for new therapeutic approaches for demyelination diseases based on the elucidation of the remyelination-promoting mechanism by LDM/CYP51Principal Investigator
- Principal Investigator
  
  Nakashima Kentaro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokushima Bunri University
Roles of SCD, an enzyme for unsaturated fatty acid synthesis, in the early lesion of Alzheimer''s model mice.
- Principal Investigator
  
  Song Si-Young
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Tokushima Bunri University
Development of a new method for molecular pathological analysis and diagnosis ~Application of the new method to analysis of neurodegenerative disease~Principal Investigator
- Principal Investigator
  
  Nakashima Kentaro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokushima Bunri University
Study of the functional role of CYP511 in myelination and remyelination.
- Principal Investigator
  
  SONG Si-Young
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokushima Bunri University

All 2022 2021 2020 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.2020
- Author(s)
  1.Iwashita S, Suzuki T, Kiriyama Y, Dohmae N, Ohoka Y, Song SY, Nakashima K.
- Journal Title
  
  Biosci Rep
  
  Volume: 40(6) Issue: 6 Pages: 1-16
- DOI
  10.1042/bsr20194012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07026, KAKENHI-PROJECT-19K16623
[Presentation] Behavioral disorders and expression changes of the tyrosine hydroxylase in Cuprizone-induced neuroinflammation mouse model with schizophrenia-like symptoms.2022
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Takashi Tominaga, Yasushi Kishimoto, Kentaro Nakashima
- Organizer
  Society for Neuroscience, 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] Remyelination following demyelination induced by cuprizone is accelerated by oligodendrocyte-specific up-regulation of Lanosterol 14 alpha-demethylase (LDM, CYP51).2022
- Author(s)
  Kentaro Nakashima, Kyoka Tsukuda, Raimu Kohara, Hikaru Fukui, Maho Saito, Ryoma kawada, Si-Young Song
- Organizer
  The 45th Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] A Cuprizone-induced neuroinflammation mouse model with prepulse inhibition deficit exhibited a complementary tyrosine hydroxylase abundance ratio in the prefrontal cortex and midbrain.2022
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Yasushi Kishimoto, Kentaro Nakashima, Takashi Tominaga
- Organizer
  The 45th Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] Immunohistochemical analyses for molecules relating to schizophrenia in short-term treated mice by cuprizone with impairment of prepulse inhibition.2022
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Takashi Tominaga, Yasushi Kishimoto, Kentaro Nakashima
- Organizer
  The 45th Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] A mouse model of acute neuroinflammation induced by short-term exposure to Cuprizone show phychobehavioral disorders similar to schizophrenia2021
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Yasushi Kishimoto, Kentaro Nakashima
- Organizer
  The 44th Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] Highly expression of Lanosterol 14 alpha-demethylase (LDM, CYP51) in oligodendrocyte enhances remyelination following demyelination induced by cuprizone2021
- Author(s)
  Kentaro Nakashima, Kyoka Tsukuda, Raimu Kohara, Hikaru Fukui, Maho Saito, Chisato Takahashi, Ryoma Kawada, Si-Young Song
- Organizer
  The 44th Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] Acute neuroinflammation induced by short-term treatment with Cuprizone leads to behavioral disorders similar to schizophrenia2021
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Takashi Tominaga, Yasushi Kishimoto, Kentaro Nakashima
- Organizer
  The 80th Fujihara seminar
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] A mouse model of neuroinflammation induced by short-term exposure to Cuprizone show behavioral symptoms similar to schizophrenia2021
- Author(s)
  Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Takashi Tominaga, Yasushi Kishimoto, Kentaro Nakashima
- Organizer
  The 12th Annual Meeting of the Biophysical Society of Japan -Chugoku/shikoku branch-
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] N-terminus variants of Bcnt / Cfdp1, a transient chromatin remodeler: DEF / Y motif core that is adjacent to the CK2 phosphorylation sites.2020
- Author(s)
  Shintaro Iwashita, Takehiro Suzuki, Yuki Uezato, Yasunori Sugiyama, Naoshi Dohmae, Yoshiharu Ohoka, Si-Young Song, Kentaro Nakashima
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-19K16623
[Presentation] Effects of modified gene expression of lipid metabolism-related enzymes on remyelination following cuprizone-induced demyelination.2016
- Author(s)
  Si-Young Song, Naohiro Hashimoto, Rie Fujii, Kentaro Nakashima
- Organizer
  10th FENS Forum European Neuroscience
- Place of Presentation
  Bella Center, Copenhagen
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-26350984
[Presentation] Accelerated remyelination following demyelination induced by cuprizone in a transgenic mouse that shows oligodendrocyte-specific high expression of Lanosterol 14 alpha-demethylase (LDM, CYP51)2015
- Author(s)
  Kentaro Nakashima, Raimu Kohara, Hikaru Fukui, Rie Fujii, Si-Young Song
- Organizer
  The Molecular Biology Society of Japan
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860252
[Presentation] Functional analysis of lanosterol 14 alpha-demethylase (LDM, CYP51) in the processes of myelination and remyelination using oligodendrocyte-specific LDM transgenic mouse2015
- Author(s)
  Kentaro Nakashima, Raimu Kohara, Hikaru Fukui, Rie Fujii, Si-Young Song
- Organizer
  The Japan Neuroscience Society
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26860252
[Presentation] Expression of lanosterol 14alpha-demethylase in the nervous system and its role in myelination.2013
- Author(s)
  Song S.-Y., Kato C., Nakashima K.
- Organizer
  FENS Featured Regional Meeting
- Place of Presentation
  Prague Congress Centre
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Expression of lanosterol 14alpha-demethylase in the nervous system and its role in myelination2013
- Author(s)
  Song S.-Y., Kato C., Nakashima K
- Organizer
  FENS Featured Regional Meeting
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Cellular-scale gene expression analyses by laser capture microdissection for the histopathological specimens of the brain fixed with paraformaldehyde and immunostained.2012
- Author(s)
  Nakashima K., Koiso N., Kato C., Song S.-Y.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Expression of lanosterol 14alpha-demethylase (LDM, CYP51) in the central and peripheral nervous system and its changes in the processes of postnatal myelination and remyelination. Neuroscience 20112011
- Author(s)
  Song S.-Y., Kato C., Nakashima K
- Organizer
  The 34th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Cellular scale quantitative gene expression analysis of fixed pathological specimens by using laser capture microdissection2011
- Author(s)
  Nakashima K., Hashimoto N., Kato C., Song S.-Y
- Organizer
  The 34th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Expression of lanosterol 14alpha-demethylase (LDM, CYP51) in the central and peripheral nervous system and its changes in the processes of postnatal myelination and remyelination.2011
- Author(s)
  Song S.-Y., Kato C., Nakashima K
- Organizer
  The 34th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Cellular-scale gene expression analyses by laser capture microdissection for the histopathological specimens of the brain fixed with paraformaldehyde and immunostained2011
- Author(s)
  Nakashima K., Koiso N., Kato C., Song S.-Y
- Organizer
  The 35th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Quantitative analysis of gene expression at cellular-scale using laser capture microdissection and real-time PCR2011
- Author(s)
  Nakashima K., Hashimoto N., Kato C., Song S.-Y
- Organizer
  Neuroscience 2011, The 41th annual meeting of the Society for Neuroscience
- Place of Presentation
  Washington DC, U.S.A
- Data Source
  KAKENHI-PROJECT-23500404
[Presentation] Expression changes of Stearoyl-CoA desaturase isoforms in neuronal and glial cells during the processes of demyelination and neurodegeneration
- Author(s)
  Kentaro Nakashima, Hikaru Fukui, Rie Fujii, Si-Young Song
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860252
[Presentation] Expression changes of Stearoyl-CoA desaturase isoforms in neuronal and glial cells during the processes of demyelination and neurodegeneration.
- Author(s)
  Nakashima K., Fukui H., Fujii R., Song S.-Y.
- Organizer
  日本神経科学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26350984

1. SONG Si-Young (00399693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 安達栄治郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 大岡嘉治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakashima Kentaro 中島 健太郎

中島 健太郎 ナカシマ ケンタロウ

NAKASHIMA Kentaro 中島 健太郎

Research Projects

Research Products

Co-Researchers

グリア細胞の協調的コレステロール代謝制御による髄鞘再生促進の分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Search for new therapeutic approaches for demyelination diseases based on the elucidation of the remyelination-promoting mechanism by LDM/CYP51Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of SCD, an enzyme for unsaturated fatty acid synthesis, in the early lesion of Alzheimer''s model mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new method for molecular pathological analysis and diagnosis ~Application of the new method to analysis of neurodegenerative disease~Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the functional role of CYP511 in myelination and remyelination.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Behavioral disorders and expression changes of the tyrosine hydroxylase in Cuprizone-induced neuroinflammation mouse model with schizophrenia-like symptoms.2022

Author(s)

Organizer

Data Source

[Presentation] Remyelination following demyelination induced by cuprizone is accelerated by oligodendrocyte-specific up-regulation of Lanosterol 14 alpha-demethylase (LDM, CYP51).2022

Author(s)

Organizer

Data Source

[Presentation] A Cuprizone-induced neuroinflammation mouse model with prepulse inhibition deficit exhibited a complementary tyrosine hydroxylase abundance ratio in the prefrontal cortex and midbrain.2022

Author(s)

Organizer

Data Source

[Presentation] Immunohistochemical analyses for molecules relating to schizophrenia in short-term treated mice by cuprizone with impairment of prepulse inhibition.2022

Author(s)

Organizer

Data Source

[Presentation] A mouse model of acute neuroinflammation induced by short-term exposure to Cuprizone show phychobehavioral disorders similar to schizophrenia2021

Author(s)

Organizer

Data Source

[Presentation] Highly expression of Lanosterol 14 alpha-demethylase (LDM, CYP51) in oligodendrocyte enhances remyelination following demyelination induced by cuprizone2021

Author(s)

Organizer

Data Source

[Presentation] Acute neuroinflammation induced by short-term treatment with Cuprizone leads to behavioral disorders similar to schizophrenia2021

Author(s)

Organizer

Data Source

[Presentation] A mouse model of neuroinflammation induced by short-term exposure to Cuprizone show behavioral symptoms similar to schizophrenia2021

Author(s)

Organizer

Data Source

[Presentation] N-terminus variants of Bcnt / Cfdp1, a transient chromatin remodeler: DEF / Y motif core that is adjacent to the CK2 phosphorylation sites.2020

Author(s)

Organizer

Data Source

[Presentation] Effects of modified gene expression of lipid metabolism-related enzymes on remyelination following cuprizone-induced demyelination.2016

Author(s)

Organizer

Nakashima Kentaro 中島健太郎

中島健太郎ナカシマケンタロウ

NAKASHIMA Kentaro 中島健太郎