Otakara Kazuhiro 大宝和博

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Ohtakara Kazuhiro 大宝和博

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Researcher Number	20452146
Other IDs	https://orcid.org/0000-0002-1242-8341
Affiliation (Current)	2025: 愛知医科大学, 愛知医科大学, 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 愛知医科大学, 愛知医科大学, 客員研究員 2020 – 2021: 愛知医科大学, 公私立大学の部局等, 客員研究員 2018 – 2019: 名古屋大学, 医学系研究科, 准教授 2014 – 2015: 朝日大学, 歯学部, 教授 2013: 岐阜大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science
Keywords	Principal Investigator 低侵襲治療 / 高精度放射線治療 / 光子線 / 定位放射線照射 / 脳血管奇形 / 脳動静脈奇形 / 脳卒中 / 定位放射線治療 / 緩和医療 / 強度変調回転照射 … More / 線量分布 / 生物学的等価線量 / 転移性脳腫瘍 / 放射線科学 / 低侵襲 / 脳血管障害 / 硬膜動静脈瘻 Less

Development of physically and biologically conformal high-precision photon irradiation strategy tailored to the clinicopathological features of metastatic brain tumorsPrincipal Investigator
- Principal Investigator
  
  大宝和博
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Aichi Medical University
Improvement of precision and less invasiveness on frameless photon radiosurgery for intracranial vascular malformationsPrincipal Investigator
- Principal Investigator
  
  Ohtakara Kazuhiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Aichi Medical University
  Nagoya University
Development of less invasive and high-precision frameless stereotactic irradiation for intracranial vascular malformationsPrincipal Investigator
- Principal Investigator
  
  Ohtakara Kazuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Asahi University
  Gifu University

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Serum CYFRA 21-1 Level as a Prognostic Marker for Extensive Disease Small Cell Lung Cancer2024
- Author(s)
  Makoto Nakao, Ryosuke Kinoshita, Mamiko Kuriyama, Hiroko Kiyotoshi, Masahiro Sugihara, Norihisa Takeda, Kazuhiro Ohtakara, Hideki Muramatsu
- Journal Title
  
  Anticancer Res
  
  Volume: 44 Issue: 2 Pages: 845-851
- DOI
  10.21873/anticanres.16877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Twenty-month regression following concurrent conventional whole-brain irradiation and chemoimmunotherapy for ≧3.8 cm cerebellar metastasis from small cell lung cancer.2023
- Author(s)
  Kazuhiro Ohtakara, Sosuke Arakawa, Makoto Nakao, Hideki Muramatsu, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.43759
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Local control failure after five-fraction stereotactic radiosurgery alone for symptomatic brain metastasis from squamous cell lung carcinoma despite 43 Gy to gross tumor margin with internal steep dose increase and tumor shrinkage during irradiation.2023
- Author(s)
  Kazuhiro Ohtakara, Kuniaki Tanahashi, Takeshi Kamomae, Eiji Ito, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.38645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-20K08076
[Journal Article] Volumetric-modulated arc-based re-radiosurgery with simultaneous reduced-dose whole-brain irradiation for local failures following prior radiosurgery of brain oligometastases from small cell lung cancer.2023
- Author(s)
  Kazuhiro Ohtakara, Sosuke Arakawa, Makoto Nakao, Hideki Muramatsu, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.44492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Robotic radiosurgical boost after whole-brain radiotherapy for 12 brain metastases: En bloc consecutive irradiation with comprehensively optimized single plan for eight lesions totaling 118 cc.2023
- Author(s)
  Kazuhiro Ohtakara, Kuniaki Tanahashi, Takehiro Yamada, Nobuyuki Tsunoda, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.51367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Correlation of Brain Metastasis Shrinking and Deviation During 10-Fraction Stereotactic Radiosurgery With Late Sequela: Suggesting Dose Ramification Between Tumor Eradication and Symptomatic Radionecrosis2023
- Author(s)
  Ohtakara Kazuhiro、Tanahashi Kuniaki、Kamomae Takeshi、Miyata Kazushi、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(1)
- DOI
  10.7759/cureus.33411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Gradual and Remarkable Tumor Shrinkage Following Seven-Fraction Stereotactic Radiosurgery Alone With a Marginal Dose of 48.3 Gy for Large Lobar Possibly Intra-sulcal Brain Metastasis From Renal Cell Carcinoma2023
- Author(s)
  Ohtakara Kazuhiro、Aoki Sachiko、Tajima Manabu、Ohno Takato、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(3)
- DOI
  10.7759/cureus.36346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Ten-Fraction Stereotactic Radiosurgery With Different Gross Tumor Doses and Inhomogeneities for Brain Metastasis of >10 cc: Treatment Responses Suggesting Suitable Biological Effective Dose Formula for Single and 10 Fractions2023
- Author(s)
  Ohtakara Kazuhiro、Nakabayashi Kiyo、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(2)
- DOI
  10.7759/cureus.34636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Five-fraction radiosurgery using a biologically equivalent dose of a single fraction of 24 Gy for a 3-cm parasagittal para-central sulcus brain metastasis from adenocarcinoma of the cecum.2023
- Author(s)
  Kazuhiro Ohtakara, Takanori Kondo, Yuma Obata, Kentaro Fujii, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.48799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Five-fraction stereotactic radiosurgery with non-contrast-enhanced MRI-based target definition and moderate dose spillage margin for limited brain metastases with impaired renal function.2023
- Author(s)
  Kazuhiro Ohtakara, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.37384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Five-Year Sustained Complete Remission With Minimal Adverse Effects Following Radiosurgery for 2-cm Brain Metastasis With Deep Eloquent Location From Lung Adenocarcinoma Despite Low Marginal Dose and High 12 Gy Volume2023
- Author(s)
  Ohtakara Kazuhiro、Nakao Makoto、Muramatsu Hideki、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(3)
- DOI
  10.7759/cureus.36680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Nineteen-month immunity to adverse radiation effects following 5-fraction re-radiosurgery with 43.6 Gy for local progression after prior 3-fraction radiosurgery for brain metastasis from pan-negative lung adenocarcinoma.2023
- Author(s)
  Kazuhiro Ohtakara, Makoto Nakao, Hideki Muramatsu, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.46374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Fifteen-fraction radiosurgery followed by reduced-dose whole-brain irradiation with a total biologically effective dose of >90-100 Gy for a locally invasive brain metastasis from lung adenocarcinoma with a high dissemination potential.2023
- Author(s)
  Kazuhiro Ohtakara, Fumiharu Ohka, Kuniaki Tanahashi, Takehiro Yamada, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.49596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Modified Dynamic Conformal Arcs With Forward Planning for Radiosurgery of Small Brain Metastasis: Each Double Arc and Different To-and-Fro Leaf Margins to Optimize Dose Gradient Inside and Outside the Gross Tumor Boundary2023
- Author(s)
  Ohtakara Kazuhiro、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(2)
- DOI
  10.7759/cureus.34831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] An Extremely Inhomogeneous Gross Tumor Dose is Suitable for Volumetric Modulated Arc-Based Radiosurgery with a 5-mm Leaf-Width Multileaf Collimator for Single Brain Metastasis2023
- Author(s)
  Ohtakara Kazuhiro、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 15(2)
- DOI
  10.7759/cureus.35467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] 5-fraction re-radiosurgery for progression following 8-fraction radiosurgery of brain metastases from lung adenocarcinoma: importance of gross tumor coverage with biologically effective dose ≧80 Gy and internal dose increase.2023
- Author(s)
  Kazuhiro Ohtakara, Kuniaki Tanahashi, Takeshi Kamomae, Kojiro Suzuki
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.42299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-20K08076
[Journal Article] 脳転移に対する定位照射: より優れた腫瘍奏功とその長期維持を得るために必要な要素2023
- Author(s)
  大宝和博
- Journal Title
  
  日本放射線技術学会放射線治療部会誌
  
  Volume: 43 Pages: 72-77
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Frameless Co-Registration of Biplane 2D Digital Subtraction Angiography Whole Frames and 3D Rotational Angiography-Based Cone-Beam Computed Tomography Angiogram on Dedicated Software for Stereotactic Radiosurgery of Cranial Vascular Malformations2022
- Author(s)
  Ohtakara Kazuhiro、Izumi Takashi、Tanahashi Kuniaki、Kamomae Takeshi、Suzuki Kojiro
- Journal Title
  
  Cureus
  
  Volume: 14(8)
- DOI
  10.7759/cureus.27983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Direct intracranial invasion of eccrine spiradenocarcinoma of the scalp: a case report and literature review2022
- Author(s)
  Kibe Yuji、Tanahashi Kuniaki、Ohtakara Kazuhiro、Okumura Yuka、Ohka Fumiharu、Takeuchi Kazuhito、Nagata Yuichi、Motomura Kazuya、Akahori Sho、Mizuno Akihiro、Sasaki Hiroo、Shimizu Hiroyuki、Yamaguchi Junya、Nishikawa Tomohide、Yokota Kenji、Saito Ryuta
- Journal Title
  
  BMC Neurology
  
  Volume: 22(1) Issue: 1 Pages: 223-223
- DOI
  10.1186/s12883-022-02749-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-20K17928
[Journal Article] The Incidence and Its Associated Factors Relevant to Brain Radionecrosis That Requires Intervention Following Single or Fractionated Stereotactic Radiosurgery Using Vero4DRT for Brain Metastases2022
- Author(s)
  Yamada Takehiro、Ohtakara Kazuhiro、Kamomae Takeshi、Itoh Junji、Shimada Hideki、Ishihara Shunichi、Naganawa Shinji
- Journal Title
  
  Cureus
  
  Volume: 14(6)
- DOI
  10.7759/cureus.25888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07561
[Journal Article] Development of an x-ray-opaque-marker system for quantitative phantom positioning in patient-specific quality assurance2021
- Author(s)
  Kentaro Suzuki, Takeshi Kamomae, Hiroshi Oguchi, Fumitaka Kawabata, Kazuma Sugita, Kuniyasu Okudaira, Masaki Mori, Shinji Abe, Masataka Komori, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
- Journal Title
  
  Phys Med
  
  Volume: 91 Pages: 121-130
- DOI
  10.1016/j.ejmp.2021.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07671, KAKENHI-PROJECT-18K04974, KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-20K08076
[Journal Article] 頭蓋内血管奇形に対する定位照射標的定義におけるElements Cranial Vascular (Image Fusion Angio, SmartBrush) を用いた2D-DSA 全フレームペア画像の3D 画像への統合: 空間・時間分解能向上による4次元標的定義2021
- Author(s)
  大宝和博
- Journal Title
  
  Brainlab User Report
  
  Volume: 42 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] Early glottic cancer treatment with concurrent chemoradiotherapy with once-daily orally administered S-12021
- Author(s)
  Yuuki Takase, Yoshiyuki Itoh, Kazuhiro Ohtakara, Mariko Kawamura, Junji Ito, Yumi Oie, Tamami Ono, Yutaro Sasaki, Ayumi Nishida, Shinji Naganawa
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 83 Issue: 2 Pages: 251-258
- DOI
  10.18999/nagjms.83.2.251
- NAID
  120007127073
- ISSN
  0027-7622
- URL
  https://nagoya.repo.nii.ac.jp/records/2001158
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07671, KAKENHI-PROJECT-21K07561
[Journal Article] Stereotactic body radiation therapy for Japanese patients with localized prostate cancer: 2-year results and predictive factors for acute genitourinary toxicities2021
- Author(s)
  Ito Makoto、Yoshioka Yasuo、Takase Yuuki、Suzuki Junji、Matsunaga Takuma、Takahashi Hironori、Takeuchi Arisa、Adachi Sou、Abe Souichirou、Oshima Yukihiko、Ohtakara Kazuhiro、Suzuki Kojiro、Okuda Takahito
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 51 Issue: 8 Pages: 1253-1260
- DOI
  10.1093/jjco/hyab094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10392, KAKENHI-PROJECT-18K07671, KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-21K07715, KAKENHI-PROJECT-20K16741
[Journal Article] 頭蓋内血管奇形に対する定位照射標的定義におけるElements Cranial Vascular (Image Fusion Angio, SmartBrush) を用いた2D-DSA 全フレームペア画像の3D 画像への統合: 空間・時間分解能向上による4次元標的定義2021
- Author(s)
  大宝和博
- Journal Title
  
  Brainlab User Report RT-CR042-Rev.01
  
  Volume: 42 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] Dosimetric impacts of beam-hardening filter removal for the CyberKnife system2021
- Author(s)
  Takeshi Kamomae, Takuma Matsunaga, Junji Suzuki, Kuniyasu Okudaira, Fumitaka Kawabata, Yutaka Kato, Hiroshi Oguchi, Morihito Shimizu, Motoharu Sasaki, Yuki Takase, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
- Journal Title
  
  Phys Med
  
  Volume: 86 Pages: 98-105
- DOI
  10.1016/j.ejmp.2021.05.011
- NAID
  120007183206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07671, KAKENHI-PROJECT-21K07561, KAKENHI-PROJECT-20K08076
[Journal Article] 転移性脳腫瘍に対する定位放射線治療：標的定義・線量分布・線量分割方針2020 update2020
- Author(s)
  大宝和博
- Journal Title
  
  BrainLAB User Report RT-CR037-Rev.01
  
  Volume: 1 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] Evaluation of newly implemented dose calculation algorithms for multileaf collimator-based CyberKnife tumor-tracking radiotherapy.2020
- Author(s)
  Kohei Kawata, Takeshi Kamomae, Hiroshi Oguchi, Fumitaka Kawabata, Kuniyasu Okudaira, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
- Journal Title
  
  Med Phys
  
  Volume: 47 Issue: 3 Pages: 1391-1403
- DOI
  10.1002/mp.14013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07671, KAKENHI-PROJECT-18K19510, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-17K15800
[Journal Article] - 最先端医療の今 - 転移性脳腫瘍に対する病理病態を考慮した生物学的原体性の高い定位放射線照射2020
- Author(s)
  大宝和博
- Journal Title
  
  Medical Science Digest
  
  Volume: 46 Pages: 54-59
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] 脳転移に対する定位放射線照射：特に大型病変に対する対応2019
- Author(s)
  大宝和博
- Journal Title
  
  JCRニュース(日本放射線科専門医会・医会誌)
  
  Volume: 231 Pages: 15-17
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] Significance of total colonoscopy screening before definitive radiotherapy for prostate cancer on the detection of anorectocolonic disease requiring intervention in advance.2018
- Author(s)
  Masahiro Nakano, Hiroshi Araki, Kazuhiro Ohtakara, Hidekazu Tanaka, Koji Iinuma, Takashi Deguchi.
- Journal Title
  
  Int J Urol
  
  Volume: 25 Issue: 2 Pages: 166-168
- DOI
  10.1111/iju.13494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] 大型肝癌に対する光子線高精度照射の意義：意図的不均一PTV線量・辺縁処方による定位照射技術の活用2018
- Author(s)
  大宝和博、谷口拓矢、小島孝雄、大洞昭博、久米真
- Journal Title
  
  定位的放射線治療
  
  Volume: 22 Pages: 113-123
- Data Source
  KAKENHI-PROJECT-18K07671
[Journal Article] 脳動静脈奇形に対するElekta Synergyを用いたフレームレス画像誘導定位手術的照射：運用法と初期経験2016
- Author(s)
  大宝和博、谷口拓矢、大野光生、白木勝彦、武居啓晃、山下健太郎、石澤錠二、郭泰彦
- Journal Title
  
  定位的放射線治療
  
  Volume: 20 Pages: 17-27
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Comparison of pencil beam-based homogeneous vs inhomogeneous target dose planning for stereotactic body radiotherapy of peripheral lung tumors through Monte Carlo-based recalculation2015
- Author(s)
  Ohtakara K, Hoshi H
- Journal Title
  
  Med Dosim
  
  Volume: 40 Issue: 3 Pages: 248-255
- DOI
  10.1016/j.meddos.2015.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Cerebral cyst formation following stereotactic ablative irradiation for non-nasopharyngeal head and neck malignancies: imaging findings and relevant dosimetric parameters.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  Br J Radiol
  
  Volume: 87 Issue: 1037 Pages: 20140071-20140071
- DOI
  10.1259/bjr.20140071
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Long-term tumor control despite late pseudoprogression on(18)F-FDG-PET following extremely hypofractionated stereotactic radiotherapy for retropharyngeal lymph node metastasis from esthesioneuroblastoma.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  Case Rep Oncol
  
  Volume: 18 Issue: 2 Pages: 576-582
- DOI
  10.1159/000366193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Stereotactic radiotherapy planning using modified dynamic conformal arcs under considering the possibility for amended visual organ displacement resulting from early tumor shrinkage during treatment for perioptic involvement of myeloma.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  International Journal of Medical Physics, Clinical Engineering and Radiation Oncology
  
  Volume: 3 Issue: 03 Pages: 183-192
- DOI
  10.4236/ijmpcero.2014.33024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Gradual recovery from nonambulatory quadriparesis caused by metastatic epidural cervical cord compression in an octogenarian gallbladder carcinoma patient treated with image-guided three-dimensional conformal radiotherapy alone using a field-in-field technique.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  Case Rep Oncol Med
  
  Volume: 2014 Pages: 389208-389208
- DOI
  10.1155/2014/398208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Early manifestation of communicating hydrocephalus after fractionated stereotactic radiotherapy for aggressive giant atypical prolactinoma.2014
- Author(s)
  Ohtakara K, Ohe N, Iwama T, Hoshi H.
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Pages: 2509-2515
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Target volume geometric change and/or deviation from the cranium during fractionated stereotactic radiotherapy for brain metastases: potential pitfalls in image guidance based on bony anatomy alignment.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  J Med Imaging Radiat Oncol
  
  Volume: 58 Issue: 6 Pages: 729-736
- DOI
  10.1111/1754-9485.12194
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] Preliminary clinical outcomes of image-guided 3-dimensional conformal radiotherapy for limited brain metastases instead of stereotactic irradiation referral.2014
- Author(s)
  Ohtakara K, Hoshi H.
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Pages: 2997-3005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461911
[Journal Article] 頭蓋内血管奇形に対するNovalis Txを用いたフレームレス画像誘導定位手術的照射：3D回転血管造影画像の治療計画への統合による初期臨床経験2014
- Author(s)
  大宝和博、中山則之、大江直行、矢野大仁、松山勝哉、北原将司、谷口拓矢、奥田清仁、岡田仁志、岩間亨、星博昭
- Journal Title
  
  定位的放射線治療
  
  Volume: 18 Pages: 33-42
- Data Source
  KAKENHI-PROJECT-25461911
[Presentation] 肺腺癌定位照射後発症した脳病変72 ccへの拡大局所適合定位照射 BED10 ≦90 Gy/15 frと分子標的薬併用療法2024
- Author(s)
  大宝和博、黒野嵩矢、杉原雅大、露木琢司、和田健太郎、岡田健、中尾心人、村松秀樹、鈴木耕次郎
- Organizer
  第15回日本放射線外科学会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移定位照射における GTV・PTV D98・D95(%) 線量処方・評価の問題点と代替法の提案2024
- Author(s)
  大宝和博、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第37回高精度放射線外部照射部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移定位照射後局所増悪に対するBED10 80 Gyでの再定位照射:適応判断と初期経験2023
- Author(s)
  大宝和博、棚橋邦明、大岡史治、加茂前健、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第36回学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移定位照射における長期縮小維持の高率達成に必要な要素：20年余の経験に基づく知見を交えて2023
- Author(s)
  大宝和博
- Organizer
  第24回山陰放射線腫瘍学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] VMATによる脳転移定位照射における中心線量を高めた超不均一GTV線量の意義2022
- Author(s)
  大宝和博、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第35回学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 最新最適化アルゴリズムVOLOと可変式準円形コリメータIrisによる多発脳転移CyberKnife治療の革新：単一計画(パス)による包括的一連照射法2022
- Author(s)
  大宝和博、熊谷始紀、高瀬裕樹、加茂前健、棚橋邦明、大岡史治、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第35回高精度放射線外部照射部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 転移性脳腫瘍に対するVero 4DRTを用いた厳格な適応基準に基づくsingle fraction SRSの治療成績2022
- Author(s)
  山田剛大、伊藤淳二、石原俊一、加茂前健、長縄慎二、大宝和博
- Organizer
  日本放射線腫瘍学会第35回高精度放射線外部照射部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] Gamma Knife Icon 時代の転移性脳腫瘍に対する分割定位照射：最適な標的辺縁の線量勾配と分割数2022
- Author(s)
  大宝和博
- Organizer
  第19回日本ガンマナイフ学会学術総会ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 中枢神経転移の多様な病態に対するVMAT対応汎用Linacを活用した高精度照射の展開2022
- Author(s)
  大宝和博、寺岡広純、堀川よしみ、大島幸彦、鈴木耕次郎
- Organizer
  第58回日本医学放射線学会秋季臨床大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移10分割定位照射中の腫瘍縮小・変位と治療後経過の対比が示唆する至適線量の分水嶺2022
- Author(s)
  大宝和博、棚橋邦明、宮田一志、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第35回学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 転移性脳腫瘍に対するVero 4DRT を用いた定位放射線照射後の要治療介入放射線障害例の検討2022
- Author(s)
  山田剛大、伊藤淳二、石原俊一、加茂前健、長縄慎二、大宝和博
- Organizer
  第13回日本放射線外科学会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移分割定位照射におけるLQ model BED10に基づく3階層線量処方でのGTV辺縁内外線量勾配最適化: Elekta Agility Monaco VMATによる再現性評価と初期臨床経験2022
- Author(s)
  大宝和博、寺岡広純、堀川よしみ、鈴木耕次郎
- Organizer
  第31回日本定位放射線治療学会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移に対する定位照射: より優れた腫瘍奏功とその長期維持を得るために必要な要素2022
- Author(s)
  大宝和博
- Organizer
  第50回日本放射線技術学会秋季学術大会第85回放射線治療部会教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] Elements Angio Contouring 導入がもたらす頭蓋内血管奇形診療の革新:放射線治療医の立場から2022
- Author(s)
  大宝和博
- Organizer
  第31回脳神経外科手術と機器学会（CNTT2022）スポンサードセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] Gamma Knife Icon 時代の転移性脳腫瘍に対する分割定位照射：最適な標的辺縁の線量勾配と分割数2022
- Author(s)
  大宝和博
- Organizer
  第19回日本ガンマナイフ学会学術総会ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 頭部血管奇形に対する定位照射を含む診断治療における血管造影CBCT subtraction画像ルーチン取得とElements Angio Contouring導入がもたらす革新2022
- Author(s)
  大宝和博, 加茂前健, 泉　孝嗣, 西堀正洋, 塚田哲也, 小島健吾, 鈴木耕次郎
- Organizer
  第13回日本放射線外科学会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 基調講演1 脳転移定位照射の治療計画「至適な治療計画と処方線量」2022
- Author(s)
  大宝和博
- Organizer
  東海放射線腫瘍研究会第58回技術部会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 頭蓋内血管奇形に対するframeless radiosurgery: より高精度・安全・快適な治療体系確立に向けた近年の革新2022
- Author(s)
  大宝和博、鈴木耕次郎
- Organizer
  第58回日本医学放射線学会秋季臨床大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] Elekta Agility・MonacoによるVMATを用いた全(脳)脊髄腔照射: Dose painting含む基礎的検討と初期臨床経験2022
- Author(s)
  大宝和博、寺岡広純、加茂前健、高瀬裕樹、堀川よしみ、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第35回高精度放射線外部照射部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移に対する定位放射線照射：長期縮小維持に必要な標的辺縁線量勾配と分割数2022
- Author(s)
  大宝和博
- Organizer
  第28回徳島放射線治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] Elements Angio Contouring 導入がもたらす頭蓋内血管奇形診療の革新: 放射線治療医の立場から2022
- Author(s)
  大宝和博
- Organizer
  第31回脳神経外科手術と機器学会（CNTT2022）スポンサードセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] Linac脳定位照射におけるnon-coplanar arc(beam)使用の意義2022
- Author(s)
  大宝和博、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第35回学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 血管奇形標的定義における2D-DSA・3D回転血管造影統合におけるsubtraction像の有用性2021
- Author(s)
  大宝和博、小島健吾、泉孝嗣、西堀正洋、塚田哲也、加茂前健、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第34回学術大会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 10個程度までの複数脳転移に対する新たなサイバーナイフ治療戦略～IrisコリメータとVOLO最適化を用いたプランニングのTipsを交えて～2021
- Author(s)
  大宝和博
- Organizer
  第30回日本定位放射線治療学会アキュレイ株式会社共催ハンズオンセミナー1
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 転移性脳腫瘍に対する分割定位放射線治療：長期縮小維持を目指した治療計画2021
- Author(s)
  大宝和博
- Organizer
  令和3年度がん診療連携拠点病院機能強化事業がん医療従事者研修事業札幌医科大学放射線治療セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 転移性脳腫瘍に対する定位放射線照射の線量処方・治療計画における最適化・規定・評価法の現状と課題2021
- Author(s)
  大宝和博、鈴木耕次郎
- Organizer
  第57回日本医学放射線学会秋季臨床大会　教育展示(優秀演題賞受賞)
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 頭蓋内血管奇形に対するフレームレス定位照射標的定義における直交2方向2D-DSA全フレーム画像の3D画像への統合：前臨床評価2021
- Author(s)
  大宝和博、小島健吾、泉孝嗣、西堀正洋、塚田哲也、加茂前健、高瀬裕樹、大島幸彦、鈴木耕次郎
- Organizer
  第30回日本定位放射線治療学会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 脳転移に対するPTV(2-3 mm)・GTV辺縁へのLQモデルに基づく生物学的等価線量50・80 Gy(α/β＝10)以上の線量勾配最適化による定位放射線治療後の局所再発例の検討2021
- Author(s)
  大宝和博、棚橋邦明、大岡史治、相見有理、中林規容、熊谷始紀、高瀬裕樹、大島幸彦、鈴木耕次郎
- Organizer
  第30回日本定位放射線治療学会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移に対するPTV(2-3 mm)・GTV辺縁へのLQモデルに基づく生物学的等価線量50・80 Gy(α/β＝10)以上の線量勾配最適化による定位放射線治療後の要治療介入晩期障害例の検討2021
- Author(s)
  大宝和博、棚橋邦明、大岡史治、熊谷始紀、高瀬裕樹、大島幸彦、鈴木耕次郎
- Organizer
  第30回日本定位放射線治療学会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 脳転移に対する全脳照射併用時の定位照射至適線量分布：BED (LQ model)に基づく考察2021
- Author(s)
  大宝和博、棚橋邦明、大岡史治、高瀬裕樹、鈴木耕次郎
- Organizer
  日本放射線腫瘍学会第34回学術大会
- Data Source
  KAKENHI-PROJECT-21K07561
[Presentation] 多発脳転移（2～12）に対する単一治療計画による包括的一連照射： Iris collimatorを用いたCK-VOLO最適化によるPTV内線量勾配調整と治療時間短縮2021
- Author(s)
  大宝和博、熊谷始紀、高瀬裕樹、伊藤淳二、大家祐実、加茂前健、伊藤善之、棚橋邦明、大岡史治、夏目敦至、大島幸彦、鈴木耕次郎
- Organizer
  サイバーナイフ研究会第14回学術研究会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] “変わる！脳転移診療” 転移性脳腫瘍の定位放射線治療2020
- Author(s)
  大宝和博
- Organizer
  第151回関西Cancer Therapistの会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 新規最適化アルゴリズムに基づく最新型ロボット式定位照射システムによる頭部定位放射線照射の多様化：当院における臨床的取り組み2020
- Author(s)
  大宝和博、熊谷始紀、高瀬裕樹、伊藤淳二、棚橋邦明、大岡史治、加茂前健、伊藤善之、夏目敦至、若林俊彦
- Organizer
  第29回日本定位放射線治療学会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 転移性脳腫瘍に対しElements Multiple Brain Mets SRSをどう活かすか?：縮小維持を目指した定位放射線照射の取り組み2020
- Author(s)
  大宝和博
- Organizer
  BRAINLAB SEMINAR 2020 in 中部
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 転移性脳腫瘍に対する長期縮小維持を目指した定位放射線治療戦略2020
- Author(s)
  大宝和博
- Organizer
  令和2年度大阪府がん診療連携協議会・第1回放射線治療部会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 脳転移に対するmodified DCA：double round-trip arcs with different leaf margins2020
- Author(s)
  大宝和博
- Organizer
  日本放射線腫瘍学会第33回学術大会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 5～10個の脳転移に対するCyberknife治療における単一計画での同時照射法の有用性2020
- Author(s)
  大宝和博、熊谷始紀、高瀬裕樹、伊藤淳二、棚橋邦明、大岡史治、加茂前健、伊藤善之、長縄慎二
- Organizer
  日本放射線腫瘍学会第33回学術大会
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 転移性脳腫瘍に対する定位放射線照射の臨床2020
- Author(s)
  大宝和博
- Organizer
  Brainlab Workshop 2020 in 鹿児島
- Invited
- Data Source
  KAKENHI-PROJECT-18K07671
[Presentation] 脳動静脈奇形に対するエレクタシナジーを用いたフレームレス画像誘導定位手術的照射：運用法と初期経験2015
- Author(s)
  大宝和博、谷口拓矢、大野光生、白木勝彦、武居啓晃、山下健太郎、石澤錠二、郭泰彦
- Organizer
  第24回日本定位放射線治療学会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25461911
[Presentation] 頭蓋内血管奇形に対するNovalis・Synergyを用いたフレームレス定位手術的照射の運用と精度の評価2015
- Author(s)
  大宝和博、谷口拓矢、大野光生、白木勝彦、藪下勉、北原将司、松山勝哉、岡田仁志
- Organizer
  日本放射線腫瘍学会第28回日本高精度放射線外部照射研究会
- Place of Presentation
  京都府京都市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25461911
[Presentation] 頭蓋内血管奇形に対するNovalis Txを用いた定位放射線照射における3D回転血管造影画像統合の意義2013
- Author(s)
  大宝和博、中山則之、大江直行、矢野大仁、榎本由貴子、江頭祐介、奥田清仁、北原将司、松山勝哉、谷口拓矢、岡田仁志、岩間　亨、星　博昭
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-25461911
[Presentation] 頭蓋内血管病変に対するNovalis Txを用いたフレームレス画像誘導定位手術的照射：3D回転血管造影画像の治療計画への統合による初期臨床経験2013
- Author(s)
  大宝和博、奥田清仁、中山則之、大江直行、矢野大仁、北原将司、松山勝哉、谷口拓矢、岡田仁志、星　博昭
- Organizer
  第22回日本定位放射線治療学会
- Place of Presentation
  長島温泉ホテル花水木(三重県)
- Data Source
  KAKENHI-PROJECT-25461911
[Presentation] 頭部定位放射線治療計画の線量・質的評価における現状と問題点：至適線量の確立に向けて2013
- Author(s)
  大宝和博、星　博昭
- Organizer
  第49回日本医学放射線学会秋季臨床大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-25461911

1. 加茂前健 (60706282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 伊藤善之 (90232488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 吉岡靖生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Otakara Kazuhiro 大宝 和博

Ohtakara Kazuhiro 大宝 和博

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Co-Researchers

Development of physically and biologically conformal high-precision photon irradiation strategy tailored to the clinicopathological features of metastatic brain tumorsPrincipal Investigator

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Improvement of precision and less invasiveness on frameless photon radiosurgery for intracranial vascular malformationsPrincipal Investigator

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Development of less invasive and high-precision frameless stereotactic irradiation for intracranial vascular malformationsPrincipal Investigator

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[Journal Article] Serum CYFRA 21-1 Level as a Prognostic Marker for Extensive Disease Small Cell Lung Cancer2024

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[Journal Article] Twenty-month regression following concurrent conventional whole-brain irradiation and chemoimmunotherapy for ≧3.8 cm cerebellar metastasis from small cell lung cancer.2023

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[Journal Article] Local control failure after five-fraction stereotactic radiosurgery alone for symptomatic brain metastasis from squamous cell lung carcinoma despite 43 Gy to gross tumor margin with internal steep dose increase and tumor shrinkage during irradiation.2023

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[Journal Article] Volumetric-modulated arc-based re-radiosurgery with simultaneous reduced-dose whole-brain irradiation for local failures following prior radiosurgery of brain oligometastases from small cell lung cancer.2023

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[Journal Article] Robotic radiosurgical boost after whole-brain radiotherapy for 12 brain metastases: En bloc consecutive irradiation with comprehensively optimized single plan for eight lesions totaling 118 cc.2023

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[Journal Article] Correlation of Brain Metastasis Shrinking and Deviation During 10-Fraction Stereotactic Radiosurgery With Late Sequela: Suggesting Dose Ramification Between Tumor Eradication and Symptomatic Radionecrosis2023

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[Journal Article] Gradual and Remarkable Tumor Shrinkage Following Seven-Fraction Stereotactic Radiosurgery Alone With a Marginal Dose of 48.3 Gy for Large Lobar Possibly Intra-sulcal Brain Metastasis From Renal Cell Carcinoma2023

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[Journal Article] Ten-Fraction Stereotactic Radiosurgery With Different Gross Tumor Doses and Inhomogeneities for Brain Metastasis of &gt;10 cc: Treatment Responses Suggesting Suitable Biological Effective Dose Formula for Single and 10 Fractions2023

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[Journal Article] Five-fraction radiosurgery using a biologically equivalent dose of a single fraction of 24 Gy for a 3-cm parasagittal para-central sulcus brain metastasis from adenocarcinoma of the cecum.2023

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[Journal Article] Five-fraction stereotactic radiosurgery with non-contrast-enhanced MRI-based target definition and moderate dose spillage margin for limited brain metastases with impaired renal function.2023

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[Journal Article] Five-Year Sustained Complete Remission With Minimal Adverse Effects Following Radiosurgery for 2-cm Brain Metastasis With Deep Eloquent Location From Lung Adenocarcinoma Despite Low Marginal Dose and High 12 Gy Volume2023

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[Journal Article] Nineteen-month immunity to adverse radiation effects following 5-fraction re-radiosurgery with 43.6 Gy for local progression after prior 3-fraction radiosurgery for brain metastasis from pan-negative lung adenocarcinoma.2023

Author(s)

Otakara Kazuhiro 大宝和博

Ohtakara Kazuhiro 大宝和博

[Journal Article] Ten-Fraction Stereotactic Radiosurgery With Different Gross Tumor Doses and Inhomogeneities for Brain Metastasis of >10 cc: Treatment Responses Suggesting Suitable Biological Effective Dose Formula for Single and 10 Fractions2023