SASAI Nobuaki 笹井宣昌

… Alternative Names

笹井宣昌ササイノブアキ

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Researcher Number	20454762
Other IDs	https://orcid.org/0009-0008-0560-7553
Affiliation (Current)	2025: 鈴鹿医療科学大学, 保健衛生学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 鈴鹿医療科学大学, 保健衛生学部, 准教授 2010 – 2021: 鈴鹿医療科学大学, 保健衛生学部, 准教授 2009: Himeji Dokkyo University, 医療保健学部, 講師 2008: 姫路獨協大学, 医療保健学, 講師 2007: 姫路獨協大学, 医療保健学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 59010:Rehabilitation science-related / Rehabilitation science/Welfare engineering / Rehabilitation science/Welfare engineering Except Principal Investigator Rehabilitation science/Welfare engineering / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator 骨格筋 / 機械刺激 / 肥大 / 萎縮 / 加齢 / レジスタンストレーニング / エピジェネティックス / 肥大・萎縮 / 肥大・萎縮予防 / メモリー機能 … More / 効果持続性 / レジスタンス・トレーニング / 酸化ストレス / 炎症反応 / 理学療法 / 回復 / 収縮力 / リハビリテーション / シグナル伝達 / 収縮機能改善 / 筋萎縮 / 筋収縮力の回復 / 理学療法学 … More Except Principal Investigator 筋萎縮 / 理学療法 / マウス / 培養細胞 / 医療・福祉 / リハビリテーション / 理学療法学 / リンパ管 / 機械刺激 / 筋萎縮モデル / 廃用性筋萎縮 / 神経-筋接合部伝達効率 / 長さ-張力関係 / ストレッチ / 伝達効率 / 神経-筋接合部 / 温度 / 骨格筋 / ラット / 食事時間 / 筋萎縮軽減 / 栄養学 / 伸張刺激 / 筋萎縮抑制 Less

機械刺激による筋肥大のエピジェネティック・メモリーと加齢によるその抑制Principal Investigator
- Principal Investigator
  
  笹井宣昌
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Suzuka University of Medical Science
Memory of mechanical loading in skeletal muscle hypertrophy and atrophyPrincipal Investigator
- Principal Investigator
  
  Sasai Nobuaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Suzuka University of Medical Science
Cessation of electrically-induced contractile activity induces atrophy in hypertrophied myotubes.
- Principal Investigator
  
  Kawakami Keisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Oita University
Crosstalk between inflammation and the basic mechanisms of skeletal muscle hypertrophy or atrophyPrincipal Investigator
- Principal Investigator
  
  Sasai Nobuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Suzuka University of Medical Science
Muscle atrophy model in vitro for physical therapy research
- Principal Investigator
  
  Kawakami Keisuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Oita University
  Nagoya University
Effects of physical stimulation on contractile properties of skeletal muscle in the mammals
- Principal Investigator
  
  ISHII Yoshiki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Himeji Dokkyo University
Elucidation of the mechanism ameliorating contractile ability of atrophied skeletal musclePrincipal Investigator
- Principal Investigator
  
  SASAI Nobuaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Suzuka University of Medical Science
  Himeji Dokkyo University
Timing of feeding alters the suppressive effects of repetitive stretching on muscle atrophy in rats
- Principal Investigator
  
  INOUE-MIYAZU Masumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Aichi Medical College for Physical and Occupational Therapy
  Nagoya University

All 2021 2020 2019 2018 2015 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Cessation of electrically-induced muscle contraction activates autophagy in cultured myotubes.2020
- Author(s)
  Kiyoshi Yoshioka, Nobuaki Sasai, Yuko Kurogi, Kimihide Hayakawa, Yuta Itoh, Nobuhide Agata, Taro Murakami , Masumi Inoue-Miyazu, Masahiro Sokabe, Keisuke Kawakami
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 533 Issue: 3 Pages: 410-416
- DOI
  10.1016/j.bbrc.2020.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10797, KAKENHI-PROJECT-19K11398, KAKENHI-PROJECT-20K11156, KAKENHI-PROJECT-18H03131
[Journal Article] 筋膜による筋間連結の機能的役割-ウシガエル膝伸筋を用いた研究-2013
- Author(s)
  石井禎基,崎田正博,笹井宣昌,笠松大輔,米井信二,福田智之,土屋禎三
- Journal Title
  
  理学療法学
  
  Volume: 40(1) Pages: 16-23
- NAID
  110009594479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500488
[Journal Article] 羽状筋としての膝伸筋の機械的収縮特性:長さ-張力関係における二峰性について.2012
- Author(s)
  石井禎基,崎田正博,笹井宣昌,村上慎一郎,松本愛香,朴浩司,赤阪英樹,丸川達矢,土屋禎三
- Journal Title
  
  理学療法兵庫
  
  Volume: 17 Pages: 24-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500488
[Journal Article] Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes2010
- Author(s)
  Sasai N et al.
- Journal Title
  
  Muscle and Nerve Vol.41
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700558
[Journal Article] Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes2010
- Author(s)
  Sasai N, 他6名
- Journal Title
  
  Muscle Nerve
  
  Volume: 41巻 Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700558
[Journal Article] Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats2009
- Author(s)
  Agata N, Sasai N, Inoue-Miyazu M, Kawakami K, Hayakawa K, Kobayashi K, Sokabe M
- Journal Title
  
  MUSCLE&NERVE (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500441
[Journal Article] Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats2009
- Author(s)
  Agata N, Sasai N et al.
- Journal Title
  
  Muscle and Nerve Vol.39
  
  Pages: 456-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700558
[Journal Article] Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats2009
- Author(s)
  Agata N, Sasai N, 他5名
- Journal Title
  
  Muscle Nerve
  
  Volume: 39巻 Pages: 456-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] Myotubes aligned by linear-patterning matrix in chick primary culture2021
- Author(s)
  Nobuaki Sasai
- Organizer
  第９８回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-18K10797
[Presentation] 直線的パターニングによるトリ初代培養筋管の配向制御2021
- Author(s)
  笹井宣昌
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K10797
[Presentation] 昇段を用いた再トレーニングによるマウス骨格筋量の加速的増加2021
- Author(s)
  笹井宣昌
- Organizer
  第7回日本スポーツ理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K10797
[Presentation] 尾部懸垂マウス後肢筋における昇段運動による萎縮の予防2020
- Author(s)
  笹井宣昌
- Organizer
  第25回日本基礎理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K10797
[Presentation] 培養系における骨格筋細胞のアルブミンによる肥大2020
- Author(s)
  笹井宣昌
- Organizer
  第7回日本予防理学療法学会学術大会・第3回産業理学療法部門研究会・第3回栄養・嚥下理学療法部門研究会
- Data Source
  KAKENHI-PROJECT-18K10797
[Presentation] 廃用性筋委縮時のマウスヒラメ筋内リンパ管の分布変化について2019
- Author(s)
  川島隆史，紀瑞成，縣信秀，伊東佑太，笹井宣昌，濱田文彦，河上敬介
- Organizer
  第43回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-16K12938
[Presentation] 廃用性筋萎縮に伴い骨格筋内リンパ管数は減少する2018
- Author(s)
  川島隆史，紀瑞成，縣信秀，伊東佑太，笹井宣昌，濱田文彦，河上敬介
- Organizer
  第23回日本基礎理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-16K12938
[Presentation] Muscle inactive state is necessary to remove damaged proteins accumulated by repeated muscle contraction.2015
- Author(s)
  K Yoshioka, Y Adachi, M Inoue-Miyazu, N Agata, N Sasai, K Hayakawa, T Murakami, K Kawakami.
- Organizer
  The World Confederation for Physical Therapy Congress 2015
- Place of Presentation
  Pan Pacific Singapore(Singapore, Singapore）
- Year and Date
  2015-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25560254
[Presentation] 筋膜による骨格筋間連結が膝伸筋に及ぼす作用について.2013
- Author(s)
  石井禎基,崎田正博,笹井宣昌,福田智之,佐野俊,前河大輝,吉岡春香,土屋禎三
- Organizer
  第48回日本理学療法学術大会
- Place of Presentation
  名古屋
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Functional role of the connection between skeletal muscles by fasciae.2013
- Author(s)
  Ishii Y, Sakita M, Sasai N, TsuchiyaT
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Functional role of fasciae in a pennate muscle of frog.2012
- Author(s)
  Ishii Y, Sakita M, Sasai N, Tsuchiya T
- Organizer
  第89回日本生理学会大会.
- Place of Presentation
  松本
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] 筋膜連結が膝伸筋に及ぼす作用について.2012
- Author(s)
  石井禎基,崎田正博,笹井宣昌,福田智之,佐野俊,前河大輝,吉岡春香,土屋禎三
- Organizer
  第47回日本理学療法学術大会
- Place of Presentation
  神戸
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] 初代筋管培養細胞に対する電気刺激による形態応答2011
- Author(s)
  吉岡潔志, 笹井宣昌, 他
- Organizer
  コ・メディカル形態機能学研究会第10回学術集会
- Place of Presentation
  中部大学(春日井,愛知)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] 膝伸展筋における筋膜連結の機能的役割.2011
- Author(s)
  石井禎基,笠松大輔,米井信二,福田智之,崎田正博,笹井宣昌,土屋禎三
- Organizer
  第46回日本理学療法学術大会
- Place of Presentation
  宮崎
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] 膝伸筋筋膜の生体内における機能的役割2011
- Author(s)
  石井禎基,崎田正博,笹井宣昌,土屋禎三
- Organizer
  第66回日本体力医学会大会
- Place of Presentation
  下関
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Association between PI3K/Akt/TOR pathway and stretch-induced hypertrophy in primary cultured myotubes of chick2011
- Author(s)
  Nobuaki Sasai, et al
- Organizer
  8th International Congress of Comparative Physiology and Biochemistry
- Place of Presentation
  Nagoya Congress Center (Nagoya, Japan)
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] Association between PI3K/Akt/TOR pathway and stretch-induced hypertrophy in primary cultured chick myotubes2011
- Author(s)
  笹井宣昌
- Organizer
  第8回国際比較生理生化学会議
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] Functional role of fasciae in a whole skeletal muscle of frog.2011
- Author(s)
  Ishii Y, Sakita M, Sasai N, Tsuchiya T
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] 膝伸展筋の力学的特性-長さ‐張力関係における二峰性-.2010
- Author(s)
  石井禎基,赤阪英樹,朴浩司,松本愛香,丸川達矢,笹井宣昌,土屋禎三
- Organizer
  第45回日本理学療法学術大会
- Place of Presentation
  岐
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of primary cultured myotubes2010
- Author(s)
  笹井宣昌
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  岩手県盛岡市
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] 伸張により引き起こされる初代培養筋管細胞肥大に対するPI3K/Akt/TOR経路の関与2010
- Author(s)
  笹井宣昌, 他
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] 生体内における筋膜連結の機能的役割-膝伸展筋について-2010
- Author(s)
  石井禎基,崎田正博,笹井宣昌,土屋禎三
- Organizer
  第1回日本基礎理学療法学会学術集会
- Place of Presentation
  宮崎
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Mechanical properties of extensor muscle in knee joint in awhole muscle preparation of frog .2010
- Author(s)
  Ishii Y, Matsumoto A, Sasai N, Tsuchiya T
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22500488
[Presentation] Repetitive Stretching Suppresses Muscle Atrophy in Denervated Soleus Muscle via Akt/mTOR pathways2009
- Author(s)
  Agata N, Sasai N et al.
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-21700558
[Presentation] 自己・傍分泌を介さない伸張刺激による培養骨格筋細胞の肥大2008
- Author(s)
  笹井宣昌、縣信秀、宮津真寿美、早川公英、河上敬介
- Organizer
  第43回日本理学療法学術大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19500441
[Presentation] 周期的伸張刺激の日内頻度と筋萎縮抑制効果の関係について2007
- Author(s)
  片岡亮人、縣信秀、笹井宣昌、宮津真寿美、河上敬介
- Organizer
  第42回日本理学療法学術集会
- Place of Presentation
  新潟
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19500441
[Presentation] 周期的伸張刺激による筋萎縮抑制は蛋白質合成経路のmTORが関与する2007
- Author(s)
  縣信秀、笹井宣昌、宮津真寿美、河上敬介、小林邦彦
- Organizer
  第42回日本理学療法学術集会
- Place of Presentation
  新潟
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19500441
[Presentation] ラット足関節背屈運動を制御し、同時に関節トルクを測定できる装置の開発2007
- Author(s)
  川島隆史、縣信秀、笹井宣昌、宮津真寿美、山本創太、河上敬介
- Organizer
  第12回理学療法の医学的基礎学術集会
- Place of Presentation
  新潟
- Year and Date
  2007-05-27
- Data Source
  KAKENHI-PROJECT-19500441
[Presentation] 伸張刺激による培養骨格筋細胞肥大の分子メカニズム-MEK/ERK経路を抑制しても筋細胞が肥大した-2007
- Author(s)
  笹井宣昌、縣信秀、宮津真寿美、河上敬介、早川公英、小林邦彦
- Organizer
  第42回日本理学療法学術集会
- Place of Presentation
  新潟
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19500441
[Presentation] 短時間の筋収縮停止はタンパク質分解とともに筋収縮構成タンパク質の合成を亢進させる
- Author(s)
  吉岡潔志，黒木優子，笹井宣昌，早川公英，村上太郎，宮津真寿美，河上敬介
- Organizer
  第49回日本理学療法学術大会
- Place of Presentation
  横浜
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-25560254
[Presentation] オートファジーによる蛋白質分解は，筋収縮減少の数時間後に起こる蛋白質合成の促進に関与しない
- Author(s)
  黒木優子，吉岡潔志，笹井宣昌，早川公英，村上太郎，宮津真寿美，河上敬介
- Organizer
  第49回日本理学療法学術大会
- Place of Presentation
  横浜
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-25560254

1. KAWAKAMI Keisuke (60195047)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. INOUE-MIYAZU Masumi (50335056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. HASEGAWA Noboru (10156317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MURAKAMI Taro (10252305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHII Yoshiki (40441331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
6. TSUCHIYA Teizo (30091036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAKITA Masahiro (10582190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 相川悠貴 (10815749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 三浦英和 (50451894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KUROGI Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. YOSHIOKA Kiyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. KAWASHIMA takafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 土屋てい三

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results

SASAI Nobuaki 笹井 宣昌

笹井 宣昌 ササイ ノブアキ

Research Projects

Research Products

Co-Researchers

機械刺激による筋肥大のエピジェネティック・メモリーと加齢によるその抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Memory of mechanical loading in skeletal muscle hypertrophy and atrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cessation of electrically-induced contractile activity induces atrophy in hypertrophied myotubes.

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Crosstalk between inflammation and the basic mechanisms of skeletal muscle hypertrophy or atrophyPrincipal Investigator

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Muscle atrophy model in vitro for physical therapy research

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Effects of physical stimulation on contractile properties of skeletal muscle in the mammals

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Elucidation of the mechanism ameliorating contractile ability of atrophied skeletal musclePrincipal Investigator

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Timing of feeding alters the suppressive effects of repetitive stretching on muscle atrophy in rats

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[Journal Article] Cessation of electrically-induced muscle contraction activates autophagy in cultured myotubes.2020

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[Journal Article] 筋膜による筋間連結の機能的役割-ウシガエル膝伸筋を用いた研究-2013

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[Journal Article] 羽状筋としての膝伸筋の機械的収縮特性:長さ-張力関係における二峰性について.2012

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[Journal Article] Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes2010

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[Journal Article] Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes2010

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[Journal Article] Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats2009

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[Journal Article] Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats2009

SASAI Nobuaki 笹井宣昌

笹井宣昌ササイノブアキ