Sakairi Toru 坂入徹

… Alternative Names

坂入徹サカイリトオル

SAKAIRI Toru 坂入徹

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Researcher Number	20455976
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 群馬大学, 大学院医学系研究科, 助教 2016 – 2019: 群馬大学, 大学院医学系研究科, 助教 2014 – 2016: 群馬大学, 医学(系)研究科(研究院), 助教 2014: 群馬大学, 大学院医学系研究科, 助教 2013: 群馬大学, 医学部附属病院, 助教 2011 – 2012: 群馬大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Kidney internal medicine
Keywords	Principal Investigator 糸球体上皮細胞 / TGF-β / Wilms tumor 1 / TGF-beta / WT1 / TGF-beta1 / 巣状糸球体硬化症 / 糖尿病性腎症 / microRNA / ポドサイト … More / miR-145 / miR-143 / 糖尿病性腎臓病 / マイクロRNA / 巣状分節性糸球体硬化症 / micro RNA / hsa-miR-143 / micro-RNA / 急性腎障害 / 慢性腎臓病 / 腎線維化 / 虚血再灌流モデル / 片側尿管結紮モデル / アンドロゲン受容体 / podocyte / TGF-beta 1 … More Except Principal Investigator 糸球体上皮細胞 / SIRP-α / Ship-1 / チロシン脱リン酸化酵素 / 間質性腎炎 / 自己免疫 / 樹状細胞 / SHP-1 / チロシンキナーゼ / 国際情報交換　米国 / 国際情報交換 / 蛋白尿 / ネフローゼ症候群 / mTOR経路 / sestrin 2 / 糸球体障害 / ボウマン嚢上皮細胞 Less

糖尿病性腎臓病へのmiR-143/145の関与を明らかにするPrincipal Investigator
- Principal Investigator
  
  坂入徹
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Gunma University
Involvement of hsa-miR-143 in podocyte injury by TGF-betaPrincipal Investigator
- Principal Investigator
  
  Sakairi Toru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
チロシン脱リン酸化系シグナル分子の遺伝子改変マウスを用いた腎炎発症機序の解明
- Principal Investigator
  
  野島美久
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
The role of an androgen receptor signal on progression of kidney diseasesPrincipal Investigator
- Principal Investigator
  
  Sakairi Toru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
Analysis of Glomerular Injury: The Signal Transduction Pathway of Bowman's Epithelial Cells"
- Principal Investigator
  
  HIROMURA Keiju
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
Effect of TGF-β on WT1 expression in podocyte.Principal Investigator
- Principal Investigator
  
  SAKAIRI Toru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University

All 2023 2016 2014 2011 2010 Other

All Journal Article Presentation

[Journal Article] The miR-143/145 cluster induced by TGF-β1 suppresses Wilms’ tumor 1 expression in cultured human podocytes2023
- Author(s)
  Tabei Akifumi、Sakairi Toru、Hamatani Hiroko、Ohishi Yuko、Watanabe Mitsuharu、Nakasatomi Masao、Ikeuchi Hidekazu、Kaneko Yoriaki、Kopp Jeffrey B.、Hiromura Keiju
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 325 Issue: 1 Pages: F121-F133
- DOI
  10.1152/ajprenal.00313.2022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08302
[Journal Article] Expression of a novel stress-inducible protein, sestrin 2, in rat glomerular parietal epithelial cells2014
- Author(s)
  Hiroko Hamatani, Keiju Hiromura, Toru Sakairi, Satoshi Takahashi, Mitsuharu Watanabe, Akito Maeshima, Takamoto Ohse, Jeffery W Pippin, Stuart J Shankland, Yoshihisa Nojima
- Journal Title
  
  American Journal of Physiology Renal Physiology
  
  Volume: 307 Issue: 6 Pages: F708-F717
- DOI
  10.1152/ajprenal.00625.2013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591188
[Journal Article] TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes.2011
- Author(s)
  Sakairi T, Abe Y, Kopp JB.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 26 Issue: 9 Pages: 2746-2752
- DOI
  10.1093/ndt/gfr061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790930
[Journal Article] TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes2011
- Author(s)
  Sakairi T, Abe Y, Kopp JB
- Journal Title
  
  Nephrol DialTransplant
  
  Volume: 26(9) Pages: 2746-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] The miR-143/145 Cluster Induced by TGF-β1 Suppresses Wilms Tumor 1 Expression in Cultured Human Podocytes2023
- Author(s)
  Tabei Akifumi、Sakairi Toru、Ohishi Yuko、Watanabe Mitsuharu、Nakasatomi Masao、Hamatani Hiroko、Ikeuchi Hidekazu、Kaneko Yoriaki、Kopp Jeffrey B.、Hiromura Keiju
- Organizer
  American Society of Nephrology Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08302
[Presentation] MiR-143/145はTGF-β1による糸球体上皮細胞障害に関与している2023
- Author(s)
  田部井彬史, 坂入徹, 浜谷博子, 大石裕子, 渡辺光治, 中里見征央, 池内秀和, 金子和光, 廣村桂樹
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08302
[Presentation] 樹状細胞特異的Shp1欠損マウスにおける自己免疫性腎炎の解析：第2報2016
- Author(s)
  渡辺光治,廣村桂樹,金子和光,大石裕子,木下雅人, 坂入徹, 池内秀和, 前嶋明人, 大西浩史,的崎尚,野島美久
- Organizer
  第59回日本腎臓学会総会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26461213
[Presentation] Accumulation of Dysregulated Renal Mononuclear Phagocytes (rMoPh)and Th1 cells in the Kidney of CD11c-specific SHP-1 Knockout Mice2016
- Author(s)
  Mitsuharu Watanabe, Keiju Hiromura, Yoriaki Kaneko, Yuko Ohishi, Masato Kinoshita, Toru Sakairi, Hidekazu Ikeuchi, Akito Maeshima, Hiroshi Ohnishi, Takashi Matozaki, Yoshihisa Nojima
- Organizer
  第49回米国腎臓学会
- Place of Presentation
  シカゴ
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-26461213
[Presentation] ボーマン嚢上皮細胞における新規ストレス誘導蛋白sestrin-2の発現に関する検討2014
- Author(s)
  浜谷博子、廣村桂樹、坂入　徹、渡辺光治、大瀬貴元, Shankland Stuart、野島美久
- Organizer
  第5回分子腎臓フォーラム
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24591188
[Presentation] A Novel Case of Nephrotic Syndrome Caused by Immune-Mediated Severe LCAT Deficiency.2011
- Author(s)
  Takahashi S, Hiromura K, Tsukida M, Ohishi Y, Hamatani H, Sakurai N, Sakairi T, Ikeuchi H, Maeshima A, Kuroiwa T, Nagata M, and Nojima Y.
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] TGF-beta1 は、糸球体上皮細胞におけるWT1の発現を抑制する2011
- Author(s)
  坂入　徹、阿部　祥英、廣村　桂樹、高橋　哲史、浜谷　博子、櫻井　則之、池内　秀和、野島　美久、Kopp　Jeffrey
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] Transforming Growth Factor (TGF)-β1 Induced DNA Methylation of Wilms' Tumor Suppressor Gene (WT1) Promoter in Human Podocytes2011
- Author(s)
  Hamatani H, Hiromura K, Sakairi T, Takahashi S, Ikeuchi H, Maeshima A, and Nojima Y
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] miR-143 contributes to podocyte injury induced by TGF-beta12011
- Author(s)
  Sakairi T, Abe Y, Hiromura K, Takahashi S, Hamatani H, Nojima Y, and Kopp JB
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] ループス腎炎の寛解導入における、タクロリムス（TAC）とミコフェノール酸モフェチル（MMF）の併用療法の試み2011
- Author(s)
  池内　秀和、廣村　桂樹、高橋　哲史、月田　真祐子、内山　和彦、櫻井　則之、坂入　徹、前嶋　明人、黒岩　卓、野島　美久
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] 後天性LCAT欠損によるネフローゼ症候群の1例とその機序解析2011
- Author(s)
  高橋　哲史、廣村　桂樹、月田　真祐子、大石　裕子、浜谷　博子、櫻井　則之、坂入　徹、池内　秀和、前嶋　明人、黒岩　卓、長田　道夫、野島　美久
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] 複数のThymidineアナログを用いたlabel-retaining cells（LRCs）の検討2011
- Author(s)
  前嶋　明人、宮　政明、三島　敬一郎、櫻井　則之、池内　秀和、坂入　徹、黒岩　卓、廣村　桂樹、野島　美久
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] miR-143 contributes to podocyte injury induced by TGF-betal2011
- Author(s)
  Sakairi T, Abe Y, Hiromura K, TakahashiS, Hamatani H, Nojima Y, and Kopp JB
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] Transforming Growth Factor (TGF)-β1 Induced DNA Methylation of Wilms’ Tumor Suppressor Gene (WT1) Promoter in Human Podocytes.2011
- Author(s)
  Hamatani H, Hiromura K, Sakairi T, Takahashi S, Ikeuchi H, Maeshima A, Nojima Y.
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] SIRPαシグナル経路の遮断は糖尿病性腎症を増悪させる2011
- Author(s)
  高橋　哲史1、廣村　桂樹1、浜谷　博子1、加藤　麻衣1、坂入　徹、櫻井　則之、池内　秀和、前嶋　明人、黒岩　卓、青木　武生、大西　浩史、的崎　尚、野島　美久
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] TGF-beta reduces Wilms tumor 1 expression in podocytes in vitro and in vivo2010
- Author(s)
  Sakairi T, Abe Y, and Kopp JB
- Organizer
  The 43th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-23790930
[Presentation] ボーマン嚢上皮細胞(PECs)における新規ストレス誘導蛋白Sestrin-2の検討
- Author(s)
  浜谷博子、廣村桂樹、坂入徹、高橋哲史、渡辺光治、前嶋明人、大瀬貴元, Shankland Stuart、野島美久
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム，東京
- Data Source
  KAKENHI-PROJECT-24591188
[Presentation] ボーマン嚢上皮細胞(PECs)における新規ストレス誘導蛋白Sestrin-2の検討
- Author(s)
  浜谷博子、廣村桂樹、坂入徹、高橋哲史、渡辺光治、前嶋明人、大瀬貴元, Shankland Stuart、野島美久
- Organizer
  第8回弥彦ポドサイトセミナー
- Place of Presentation
  コープシティ花園　（新潟県）
- Data Source
  KAKENHI-PROJECT-24591188
[Presentation] Expression of a novel stress-inducible protein, sestrin 2, in rat glomerular parietal epithelial
- Author(s)
  Hiroko Hamatani, Keiju Hiromura, Toru Sakairi, Satoshi Takahashi, Mitsuharu Watanabe, Akito Maeshima, Takamoto Ohse, Jeffrey W Pippin, Stuart J Shankland, Yoshihisa Nojima
- Organizer
  2012年米国腎臓学会
- Place of Presentation
  米国・サンディエゴ
- Data Source
  KAKENHI-PROJECT-24591188
[Presentation] EXPRESSION OF A NOVEL STRESS-INDUCIBLE PROTEIN, SESTRIN 2, IN RAT GLOMERULAR PARIETAL EPITHELIAL CELLS
- Author(s)
  Hiroko Hamatani, Keiju Hiromura, Toru Sakairi, Satoshi Takahashi, Mitsuharu Watanabe, Akito Maeshima, Takamoto Ohse, Jeffery W. Pippin, Stuart J. Shankland, Yoshihisa Nojima
- Organizer
  The 14th Asian Pacific Congress of Nephrology 2014
- Place of Presentation
  Shinagawa Prince Hotel, Tokyo
- Data Source
  KAKENHI-PROJECT-24591188

1. HIROMURA Keiju (70292597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 野島美久 (90201699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. STUART Shankland

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Sakairi Toru 坂入 徹

坂入 徹 サカイリ トオル

SAKAIRI Toru 坂入 徹

Research Projects

Research Products

Co-Researchers

糖尿病性腎臓病へのmiR-143/145の関与を明らかにするPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of hsa-miR-143 in podocyte injury by TGF-betaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

チロシン脱リン酸化系シグナル分子の遺伝子改変マウスを用いた腎炎発症機序の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of an androgen receptor signal on progression of kidney diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Glomerular Injury: The Signal Transduction Pathway of Bowman's Epithelial Cells"

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of TGF-β on WT1 expression in podocyte.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The miR-143/145 cluster induced by TGF-β1 suppresses Wilms’ tumor 1 expression in cultured human podocytes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of a novel stress-inducible protein, sestrin 2, in rat glomerular parietal epithelial cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes2011

Author(s)

Journal Title

Data Source

[Presentation] The miR-143/145 Cluster Induced by TGF-β1 Suppresses Wilms Tumor 1 Expression in Cultured Human Podocytes2023

Author(s)

Organizer

Data Source

[Presentation] MiR-143/145はTGF-β1による糸球体上皮細胞障害に関与している2023

Author(s)

Organizer

Data Source

[Presentation] 樹状細胞特異的Shp1欠損マウスにおける自己免疫性腎炎の解析：第2報2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Accumulation of Dysregulated Renal Mononuclear Phagocytes (rMoPh)and Th1 cells in the Kidney of CD11c-specific SHP-1 Knockout Mice2016

Author(s)

Organizer

Place of Presentation

Year and Date

Sakairi Toru 坂入徹

坂入徹サカイリトオル

SAKAIRI Toru 坂入徹