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Saegusa Jun  三枝 淳

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SAEGUSA Jun  三枝 淳

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Researcher Number 20514970
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 神戸大学, 医学研究科, 准教授
2020: 神戸大学, 医学部附属病院, 准教授
2013 – 2019: 神戸大学, 医学部附属病院, 講師
2011 – 2012: 神戸大学, 医学部附属病院, 助教
2011: 神戸大学, 医学部附属病院, 特定助教
2008 – 2010: Kobe University, 医学研究科, 特命助教
2008 – 2009: 神戸大学, 大学院・医学研究科, 特命助教
Review Section/Research Field
Principal Investigator
Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology
Except Principal Investigator
Collagenous pathology/Allergology / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 58010:Medical management and medical sociology-related / Laboratory medicine
Keywords
Principal Investigator
関節リウマチ / 滑膜細胞 / 全身性自己免疫疾患 / 自己免疫疾患 / 代謝 / グルタミノリシス / グルタミン代謝 / メタボロミクス / 膠原病 / バイオマーカー … More / インテグリン / iPS細胞 / CD4陽性T細胞 / 炎症性筋疾患 / ANCA関連血管炎 / 細胞外小胞 / エクソソーム / ラパマイシン / マウス関節炎モデル / クロロキン / オートファジー / グルタミナーゼ1 / 解糖系 / グルタミン酸 / ガスクロマトグラフィー質量分析計 / 全身性エリテマトーデス / メタボローム解析 / 細胞増殖因子 / 増殖因子 / サイトカイン / インターロイキン-1 … More
Except Principal Investigator
関節リウマチ / マイクロRNA / アジュバント関節炎 / エクソソーム / QOL / 主観的幸福度 / ノンコーディングRNA / 長鎖ノンコー ディングRNA / 長鎖ノンコーディングRNA / 滑膜細胞 / 核酸 / 免疫学 / miRNA / リウマチ学 / マイクロRNA / 破骨細胞 / 蛍光相関分光法 / 生物製剤 / 転写因子 / 自己免疫疾患 Less
  • Research Projects

    (14 results)
  • Research Products

    (127 results)
  • Co-Researchers

    (17 People)
  •  Analysis of autoreactive T cells in rheumatoid arthritis using iPS cell technologyPrincipal Investigator

    • Principal Investigator
      三枝 淳
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kobe University
  •  Development of a novel diagnostic and therapeutic strategy for systemic autoimmune diseases focusing on extracellular vesiclesPrincipal Investigator

    • Principal Investigator
      Saegusa Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kobe University
  •  The fluctuation in subjective well-being of patients with early rheumatoid arthritis

    • Principal Investigator
      蔭山 豪一
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Hyogo Prefectural Amagasaki General Medical Center
  •  Inetraction of non-coding RNA specific for rheumatoid arthritis

    • Principal Investigator
      KAWANO SEIJI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kobe University
  •  Development of novel therapeutic strategies targeting cellular metabolism in autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      Saegusa Jun
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kobe University
  •  Role of exosomes in the pathology of rheumatoid arthritis

    • Principal Investigator
      Nakamachi Yuji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kobe University
  •  Study of target molecules of rheumatoid arthritis-associated miRNA.

    • Principal Investigator
      Kawano Seiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kobe University
  •  A metabolic approach for discovering therapeutic target in rheumatoid arthritis synovial fibroblastPrincipal Investigator

    • Principal Investigator
      Saegusa Jun
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kobe University
  •  Development of the novel therapy for rheumatoid arthritis by micro RNA-containing exosomes

    • Principal Investigator
      Nakamachi Yuji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kobe University
  •  Study of the role of miRNA in the regulation of osteoclast differentiation in rheunmatoid arthritis joints

    • Principal Investigator
      Kawano Seiji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kobe University
  •  Metabolomics for biomarker discovery in systemic lupus erythematosusPrincipal Investigator

    • Principal Investigator
      SAEGUSA Jun
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kobe University
  •  Development of a novel therapeutic method for rheumatoid arthritis by targeting growth factor signalingPrincipal Investigator

    • Principal Investigator
      SAEGUSA Jun
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kobe University
  •  Analysis of signaling pathways induced by the binding of IL-1・to integrinsPrincipal Investigator

    • Principal Investigator
      SAEGUSA Jun
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kobe University
  •  Development of a new assay system for transcription factor activity using FCS

    • Principal Investigator
      KUMAGAI Shunichi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kobe University

All 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 最新関節リウマチ学2014

    • Author(s)
      三枝淳,松木郁親,森信暁雄
    • Total Pages
      5
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Book] Galectins in Regulation of Inflammation and Immunity. In: Galectins.2008

    • Author(s)
      L iu FT, Hsu DK, Yang RY, Chen HY, Saegusa J.
    • Publisher
      Oxford University Press
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Identification of plexin D1 on circulating extracellular vesicles as a potential biomarker of polymyositis and dermatomyositis2022

    • Author(s)
      Uto K, Ueda K, Okano T, Akashi K, Takahashi S, Nakamachi Y, Imanishi T, Awano H, Morinobu A, Kawano S, and Saegusa J.
    • Journal Title

      Rheumatology

      Volume: 61 Issue: 4 Pages: 1669-1679

    • DOI

      10.1093/rheumatology/keab588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08906, KAKENHI-PROJECT-21K08437
  • [Journal Article] Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice2019

    • Author(s)
      Ueda Yo、Saegusa Jun、Okano Takaichi、Sendo Sho、Yamada Hirotaka、Nishimura Keisuke、Morinobu Akio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 6374-6374

    • DOI

      10.1038/s41598-019-42932-1

    • NAID

      120006624233

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387, KAKENHI-PROJECT-16K19599
  • [Journal Article] S100A12 facilitates osteoclast differentiation from human monocytes2018

    • Author(s)
      Nishida Miwa、Saegusa Jun、Tanaka Shino、Morinobu Akio
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 9 Pages: e0204140-e0204140

    • DOI

      10.1371/journal.pone.0204140

    • NAID

      120006529678

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Journal Article] Immunometabolism in rheumatoid arthritis2018

    • Author(s)
      Okano Takaichi、Saegusa Jun、Takahashi Soshi、Ueda Yo、Morinobu Akio
    • Journal Title

      Immunological Medicine

      Volume: 41 Issue: 3 Pages: 89-97

    • DOI

      10.1080/25785826.2018.1531186

    • NAID

      120006840208

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Journal Article] Myeloid-derived suppressor cells in non-neoplastic inflamed organs2018

    • Author(s)
      Sendo Sho、Saegusa Jun、Morinobu Akio
    • Journal Title

      Inflammation and Regeneration

      Volume: 38 Issue: 1

    • DOI

      10.1186/s41232-018-0076-7

    • NAID

      120006539277

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387, KAKENHI-PROJECT-16K09893
  • [Journal Article] Cardiac Dysfunction in Duchenne Muscular Dystrophy Is Less Frequent in Patients With Mutations in the Dystrophin Dp116 Coding Region Than in Other Regions2018

    • Author(s)
      Yamamoto Tetsushi、Awano Hiroyuki、Zhang Zhujun、Sakuma Mio、Kitaaki Shoko、Matsumoto Masaaki、Nagai Masashi、Sato Itsuko、Imanishi Takamitsu、Hayashi Nobuhide、Matsuo Masafumi、Iijima Kazumoto、Saegusa Jun
    • Journal Title

      Circulation: Genomic and Precision Medicine

      Volume: 11 Issue: 1

    • DOI

      10.1161/circgen.117.001782

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Journal Article] MicroRNA-124 inhibits TNF-α- and IL-6-induced osteoclastogenesis2018

    • Author(s)
      Ohnuma Kenichiro、Kasagi Shimpei、Uto Kenichi、Noguchi Yoriko、Nakamachi Yuji、Saegusa Jun、Kawano Seiji
    • Journal Title

      Rheumatology International

      Volume: 39 Issue: 4 Pages: 689-695

    • DOI

      10.1007/s00296-018-4218-7

    • NAID

      120006629301

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387, KAKENHI-PROJECT-16K09894
  • [Journal Article] CD11b+ Gr1dim tolerogenic dendritic cell-like cells are expanded in interstitial lung disease in SKG mice.2017

    • Author(s)
      Sendo S, Saegusa J, Okano T, Takahashi S, Akashi K, Morinobu A.
    • Journal Title

      Arthritis Rheumatol.

      Volume: 69 Issue: 12 Pages: 2314-27

    • DOI

      10.1002/art.40231

    • NAID

      120006621623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09525, KAKENHI-PROJECT-16K09893
  • [Journal Article] 3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation.2017

    • Author(s)
      Okano T, Saegusa J, Nishimura K, Takahashi S, Sendo S, Ueda Y, Morinobu A.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 42412-42412

    • DOI

      10.1038/srep42412

    • NAID

      120006624239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09893, KAKENHI-PROJECT-15K09525
  • [Journal Article] Direct binding to integrins and loss of disulfide linkage in IL-1beta are involved in the agonistic action of IL-1beta.2017

    • Author(s)
      Takada YK, Yu J, Fujita M, Saegusa J, Wu CY, Takada Y.
    • Journal Title

      J Biol Chem.

      Volume: 292 Issue: 49 Pages: 20067-75

    • DOI

      10.1074/jbc.m117.818302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Journal Article] Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.2017

    • Author(s)
      Takahashi S, Saegusa J, Sendo S, Okano T, Akashi K, Irino Y, Morinobu A
    • Journal Title

      Arthritis Res Ther.

      Volume: 19 Issue: 1 Pages: 76-76

    • DOI

      10.1186/s13075-017-1283-3

    • NAID

      120006318800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09893, KAKENHI-PROJECT-15K09525
  • [Journal Article] Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.2016

    • Author(s)
      Akashi K, Saegusa J, Sendo S, Nishimura K, Okano T, Yagi K, Yanagisawa M, Emoto N, Morinobu A.
    • Journal Title

      Arthritis Res Ther.

      Volume: 18 Issue: 1 Pages: 113-113

    • DOI

      10.1186/s13075-016-1011-4

    • NAID

      120007135444

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09525, KAKENHI-PROJECT-16K19599
  • [Journal Article] メタボロームに着目した膠原病の新規治療法および診断法の開発2016

    • Author(s)
      三枝淳, 蔭山豪一, 森信暁雄
    • Journal Title

      アレルギーの臨床

      Volume: 36 Pages: 1292-1297

    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Journal Article] MicroRNA-124: a promising therapeutic agent for various human diseases, including rheumatoid arthritis2016

    • Author(s)
      Nakamachi Y, Saegusa J, and Kawano S
    • Journal Title

      RNA & Disease

      Volume: 3 Pages: 1-7

    • DOI

      10.14800/rd.1252

    • Open Access
    • Data Source
      KAKENHI-PROJECT-16K09894
  • [Journal Article] Expression and Functions of Immediate Early Response Gene X-1 (IEX-1) in Rheumatoid Arthritis Synovial Fibroblasts.2016

    • Author(s)
      Morinobu A, Tanaka S, Nishimura K, Takahashi S, Kageyama G, Miura Y, Kurosaka M, Saegusa J, Kumagai S.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 10 Pages: e0164350-e0164350

    • DOI

      10.1371/journal.pone.0164350

    • NAID

      120005898575

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09525, KAKENHI-PROJECT-16K19599
  • [Journal Article] メタボロームに着目した膠原病の新規治療法および診断法の開発2015

    • Author(s)
      三枝淳, 蔭山豪一, 森信暁雄
    • Journal Title

      BIO Clinica

      Volume: 30(11) Pages: 1110-1115

    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Journal Article] Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates arthritis in SKG mice.2015

    • Author(s)
      Nishimura K, Saegusa J, Matsuki F, Akashi K, Kageyama G, Morinobu A
    • Journal Title

      Arthritis Rheumatol

      Volume: 67 Issue: 4 Pages: 893-902

    • DOI

      10.1002/art.39007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445, KAKENHI-PROJECT-15K09525
  • [Journal Article] MicroRNA-124 inhibits the progression of adjuvant-induced arthritis in rats.2015

    • Author(s)
      Nakamachi Y, Ohnuma K, Uto K, Noguchi Y, Saegusa J, Kawano S
    • Journal Title

      Ann Rheum Dis

      Volume: 印刷中 Issue: 3 Pages: 601-608

    • DOI

      10.1136/annrheumdis-2014-206417

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591445, KAKENHI-PROJECT-25461476, KAKENHI-PROJECT-15K09525
  • [Journal Article] 自己免疫疾患のメタボローム解析の未来~新規バイオマーカーの同定と病態解明を目指して~2015

    • Author(s)
      三枝淳, 河野誠司, 森信暁雄
    • Journal Title

      臨床病理

      Volume: 63(4) Pages: 498-505

    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Journal Article] Metabolomics analysis of saliva from patients with primary Sjogren's syndrome.2015

    • Author(s)
      Kageyama G, Saegusa J, Irino Y, Tanaka S, Tsuda K, Takahashi S, Sendo S, Morinobu A.
    • Journal Title

      Clinical & Experimental Immunology

      Volume: 182(2) Issue: 2 Pages: 149-153

    • DOI

      10.1111/cei.12683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Journal Article] 自己免疫疾患のメタボローム解析の未来~新規バイオマーカーの同定と病態解明を目指して~2015

    • Author(s)
      三枝淳、河野誠司、森信暁雄
    • Journal Title

      臨床病理

      Volume: 63 Pages: 498-505

    • Data Source
      KAKENHI-PROJECT-24591445
  • [Journal Article] GC/MS-based metabolomics detects metabolic alterations in serum from SLE patients.2014

    • Author(s)
      Saegusa J, Irino Y, Yoshida M, Tanaka S, Kogata Y, Kageyama G, Tsuji G, Takenawa T, Kawano S, Kumagai S, Morinobu A
    • Journal Title

      Clin Exp Rheumatol

      Volume: 32 Pages: 148-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Journal Article] CD45RA-Foxp3low non-regulatory T cells in the CCR7-CD45RA-CD27+CD28+ effector memory subset are increased in synovial fluid from patients with rheumatoid arthritis2014

    • Author(s)
      Matsuki F, Saegusa J, Nishimura K, Miura Y, Kurosaka M, Kumagai S, Morinobu A
    • Journal Title

      Cell Immunol

      Volume: 290 Issue: 1 Pages: 96-101

    • DOI

      10.1016/j.cellimm.2014.05.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Journal Article] Podoplanin is an inflammatory protein upregulated in Th17 cells in SKG arthritic joints2013

    • Author(s)
      Miyamoto Y, Uga H, Tanaka S, Kadowaki M, Ikeda M, Saegusa J, Morinobu A, Kumagai S, Kurata H
    • Journal Title

      Mol Immunol

      Volume: 54(2) Pages: 199-207

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Podoplanin is an inflammatory protein upregulated in Th17 cells in SKG arthritic joints.2013

    • Author(s)
      Miyamoto Y, Uga H, Tanaka S, Kadowaki M, Ikeda M, Saegusa J, Morinobu A, Kumagai S, Kurata H.
    • Journal Title

      Mol Immunol.

      Volume: 54 Issue: 2 Pages: 199-207

    • DOI

      10.1016/j.molimm.2012.11.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445, KAKENHI-PROJECT-24659473
  • [Journal Article] Mycophenolate mofetil versus intravenous cyclophosphamide for induction treatment of proliferative lupus nephritis in a Japanese population: a retrospective study2013

    • Author(s)
      Onishi A, Sugiyama D, Tsuji G, Nakazawa T, Kogata Y, Tsuda K, Naka I, Nishimura K, Misaki K, Kurimoto C, Hayashi H, Kageyama G, Saegusa J, Sugimoto T, Kawano S, Kumagai S, Morinobu A
    • Journal Title

      Mod Rheumatol

      Volume: 23(1) Issue: 1 Pages: 89-96

    • DOI

      10.1007/s10165-012-0634-9

    • NAID

      10031167670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790967, KAKENHI-PROJECT-24591445
  • [Journal Article] CD45RA-Foxp3high activated/effector regulatory T cells in the CCR7+CD45RA-CD27+CD28+ central memory subset are decreased in peripheral blood from patients with rheumatoid arthritis.2013

    • Author(s)
      23. Matsuki F, Saegusa J, Miyamoto Y, Misaki K, Kumagai S, Morinobu A
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 438 Issue: 4 Pages: 778-183

    • DOI

      10.1016/j.bbrc.2013.05.120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445, KAKENHI-PROJECT-24659473
  • [Journal Article] Mycophenolate mofetil versus intravenous cyclophosphamide for induction treatment of proliferative lupus nephritis in a Japanese population: a retrospective study2013

    • Author(s)
      Onishi A, Sugiyama D, Tsuji G, Nakazawa T, Kogata Y, Tsuda K, Naka I, Nishimura K, Misaki K, Kurimoto C, Hayashi H, Kageyama G, Saegusa J, Sugimoto T, Kawano S, Kumagai S, Morinobu A
    • Journal Title

      Mod Rheumatol

      Volume: 23(1) Pages: 89-96

    • NAID

      10031167670

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Tumor necrosis factor-α inhibitor-induced antiglomerular basement membrane antibody disease in a patient with rheumatoid arthritis.2012

    • Author(s)
      Nishimura K, Saegusa J, Kawano S, Morinobu A.
    • Journal Title

      J Rheumatol.

      Volume: 39 Issue: 9 Pages: 1904-5

    • DOI

      10.3899/jrheum.120325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Journal Article] A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis.2012

    • Author(s)
      Mori S.
    • Journal Title

      PLoS One.

      Volume: 8(2) Issue: 2 Pages: 20-36

    • DOI

      10.1371/journal.pone.0057927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390300, KAKENHI-PROJECT-23590446, KAKENHI-PROJECT-23659611, KAKENHI-PROJECT-24591445
  • [Journal Article] SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production2012

    • Author(s)
      Jauharoh SNA, Saegusa J, Sugimoto T, Ardianto B, Kasagi S, Sugiyama D, Kurimoto C, Tokuno O, Nakamachi Y, Kumagai S, Kawano S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417(1) Pages: 582-7

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Diagnostic Accuracy of Serum 1,3-β-D-Glucan for Pneumocystis Jiroveci Pneumonia, Invasive Candidiasis and Invasive Aspergillosis: Systematic Review and Meta-Analysis2012

    • Author(s)
      Onishi A, Sugiyama D, Kogata Y, Saegusa J, Sugimoto T, Kawano S, Morinobu A, Nishimura K, Kumagai S
    • Journal Title

      J Clin Microbiol

      Volume: 50(1) Pages: 7-15

    • NAID

      120005323616

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Anti TNF-α agent-induced anti-GBM antibody disease in a patient with rheumatoid arthritis2012

    • Author(s)
      Nishimura K, Saegusa J, Kawano S, Morinobu A
    • Journal Title

      J Rheumatol

      Volume: 39(9) Pages: 1904-5

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases2011

    • Author(s)
      Morinobu A, Tsuji G, Kasagi S, Saegusa J, Hayashi H, Nakazawa T, Kogata Y, Misaki K, Nishimura K, Sendo S, Miura N, Kawano S, Kumagai S
    • Journal Title

      Mod Rheumatol

      Volume: 21(4) Pages: 391-6

    • NAID

      10029512930

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Plasma Platelet-derived Microparticles in Patients with Connective Tissue Diseases2011

    • Author(s)
      Oyabu C, Morinobu A, Sugiyama D, Saegusa J, Tanaka S, Morinobu S, Tsuji G, Kasagi S, Kawano S, Kumagai S
    • Journal Title

      J Rheumatol

      Volume: 38(4) Pages: 680-4

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Galectin-3 and the skin2011

    • Author(s)
      Larsen L, Chen HY, Saegusa J, Liu FT
    • Journal Title

      J Dermatol Sci

      Volume: 64(2) Pages: 85-91

    • NAID

      10030893120

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Nonbacterial thrombotic endocarditis associated with cancer of unknown origin complicated with thrombus in the left auricular appendage: case report.2011

    • Author(s)
      Norisada K, Tanaka H, Onishi T, Kaneko A, Tsuji T, Yamawaki K, Ryo K, Tatsumi K, Matsumoto K, Miura N, Saegusa J, Morinaga Y, Hara S, Kawai H, Hirata K
    • Journal Title

      Cardiovasc Ultrasound

      Volume: 9 Pages: 8-8

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Galectins in regulation of apoptosis2011

    • Author(s)
      Liu FT, Yang RY, Saegusa J, Chen HY, Hsu DK
    • Journal Title

      Adv Exp Med Biol

      Volume: 705 Pages: 431-42

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice2011

    • Author(s)
      Misaki K, Morinobu A, Saegusa J, Kasagi S, Fujita M, Miyamoto Y, Matsuki F, Kumagai S
    • Journal Title

      Arthritis Res Ther

      Volume: 13(3)

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] Epidural spinal tumor and periaortitis as rare complications of Wegener's granulomatosis2011

    • Author(s)
      Kasagi S, Saegusa J, Tsuji G, Sendo S, Miura N, Hayashi H, Sugimoto T, Kawano S, Nishida K, Kakutani K, Morinobu A, Kumagai S
    • Journal Title

      Mod Rheumatol

      Volume: 21(6) Pages: 678-83

    • NAID

      10030206372

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] T cell-binding fragment of fibrinogen can prevent autoimmunity.2010

    • Author(s)
      Takada Y, Ono Y, Saegusa J, Mitsiades C, Mitsiades N, Tsai J, He Y, Maningding E, Coleman A, Ramirez-Maverakis D, Rodriquez R, Takada Y, Maverakis E. A
    • Journal Title

      J Autoimmun

      Volume: 34(4) Pages: 453-9

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] A T cell-binding fragment of fibrinogen can prevent autoimmunity.2010

    • Author(s)
      Takada Y, Ono Y, Saegusa J, Mitsiades C, Mitsiades N, Tsai J, He Y, Maningding E, Coleman A, Ramirez-Maverakis D, Rodriquez R, Takada Y, Maverakis E.
    • Journal Title

      J Autoimmun. 34(4)

      Pages: 453-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist2010

    • Author(s)
      Yamaji S, Saegusa J, Ieguchi K, Fujita M, Takada YK, Takada Y
    • Journal Title

      PLoS One

      Volume: 5(4)

    • Data Source
      KAKENHI-PROJECT-22790929
  • [Journal Article] A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.2010

    • Author(s)
      Y amaji S, Saegusa J, Ieguchi K, Fujita M, Takada YK, Takada Y.
    • Journal Title

      PLoS One. 5(4)

      Pages: 10273-10273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] The direct binding of insulin-like growth factor-1 (IGF-1) to integrin・v・3 is involved in IGF-1 signaling.2009

    • Author(s)
      Saegusa J, Yamaji S, Ieguchi K, Wu CY, Lam KS, Liu FT, Takada YK, Takada Y.
    • Journal Title

      J Biol Chem. 284(36)

      Pages: 24106-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis.2009

    • Author(s)
      Saegusa J, Hsu DK, Chen HY, Yu L, Fermin A, Fung MA, Liu FT.
    • Journal Title

      Am J Pathol. 174(3)

      Pages: 922-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis.2009

    • Author(s)
      Saegusa J
    • Journal Title

      Am J Pathol. 174

      Pages: 922-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] The direct binding of insulin-like growth factor-1(IGF-1)to integrin alphavbeta3 is involved in IGF-1 signaling2009

    • Author(s)
      Saegusa J
    • Journal Title

      J Biol Chem. 284

      Pages: 24106-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation.2008

    • Author(s)
      Saegusa J, Hsu DK, Liu W, Kuwabara I, Kuwabara Y, Yu L, Liu FT.
    • Journal Title

      J Invest Dermatol. 128(10)

      Pages: 2403-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins・v・3 and・4・1 and induces proliferation of monocytic cells in an integrin-dependent manner.2008

    • Author(s)
      Saegusa J, Akakura N, Wu CY, Hoogland C, Ma Z, Lam KS, Liu FT, Takada Y K, Takada Y.
    • Journal Title

      J Biol Chem. 283(38)

      Pages: 26107-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4betal and induces proliferation of monocytic cells in an integrin-dependent manner2008

    • Author(s)
      Saegusa J
    • Journal Title

      J Biol Chem 283

      Pages: 26107-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation.2008

    • Author(s)
      Saegusa J
    • Journal Title

      J Invest Dermatol 128

      Pages: 2403-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Journal Article] Is SS-A/Ro52 a hydrogen peroxide-sensitive signaling molecule?2007

    • Author(s)
      Nobuhara Y, Kawano S, Kageyama G, Sugiyama D, Saegusa J, Kumagai S
    • Journal Title

      Antioxid Redox Signal, 9(3)

      Pages: 385-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Journal Article] Is SS-A/Ro52 a hydrogen peroxide-sensitive signaling molecule?2007

    • Author(s)
      Nobuhara Y, Kawano S, Kageyama G, Sugiyama D, Saegusa J, Kumagai S.
    • Journal Title

      Antioxid Redox Signal 9(3)

      Pages: 385-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] 76.Identification of Plexin D1 on Circulating Extracellular Vesicles as a Potential Biomarker of Polymyositis and Dermatomyositis.2021

    • Author(s)
      Uto K, Ueda K, Okano T, Akashi K, Takahashi S, Nakamachi Y, Imanishi T, Kawano S, Yano Y, Saegusa J
    • Organizer
      American College of Rheumatology 85th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08437
  • [Presentation] Combination therapy of rapamycin and a glutamine antagonist facilitates the expansion of myeloid-derived suppressor cells and ameliorates arthritis in SKG mice.2018

    • Author(s)
      Ueda Y, Saegusa J, Okano T, Sendo S, Yamada H, Ichise Y, Naka I, Takahashi S, Akashi K, Onishi A, Morinobu A
    • Organizer
      The 19th Annual European Congress of Rheumatology - EULAR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Presentation] Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice.2018

    • Author(s)
      Sendo S, Saegusa J, Ichise Y, Yamada H, Naka I, Ueda Y, Okano T, Morinobu A
    • Organizer
      American College of Rheumatology 82nd Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Presentation] Combined inhibition of mechanistic target of rapamycin and glutamine metabolism inhibits CD4 T cell proliferation and Th17 differentiation, facilitates the expansion of myeloid-derived suppressor cells, and synergistically ameliorates arthritis in SKG mice.2018

    • Author(s)
      Ueda Y, Saegusa J, Okano T, Sendo S, Yamada H, Akashi K, Onishi A, Morinobu A
    • Organizer
      American College of Rheumatology 82nd Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08387
  • [Presentation] CD11b+Gr1dimTolerogenic Dendritic Cell-Like Cells are Expanded in Interstitial Lung Disease of SKG Mice2017

    • Author(s)
      Sendo Sho, Saegusa Jun, Ichise Yoshihide, Yamada Hirotaka, Naka Ikuko, Okano Takaichi, Takahashi Soshi, Ueda Yo, Akashi Kengo, Onishi Akira, Kogata Yoshinori, Morinobu Akio
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Glutamine metabolism plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.2017

    • Author(s)
      Takahashi S, Saegusa J, Yamada H, Ichise Y, Naka I, Okano T, Akashi K, Sendo S, Ueda Y, Onishi A, Morinobu A.
    • Organizer
      The 18th Annual European Congress of Rheumatology - EULAR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] CD11b+Gr1dim tolerogenic dendritic cell-like cells suppress the progression of interstitial lung disease in SKG mice.2017

    • Author(s)
      Sendo S, Saegusa J, Yamada H, Ichise Y, Naka I, Ueda Y, Okano T, Takahashi S, Akashi K, Onishi A, Morinobu A.
    • Organizer
      American College of Rheumatology 81 th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] CD11b+Cr1dim tolerogenic dendritic cell-like cells are expanded in interstitial lung disease in SKG mice.2017

    • Author(s)
      Sendo S, Saegusa J, Ichise Y, Yamada H, Naka I, Okano T, Takahashi S, Ueda Y, Akashi K, Onishi A, Morinobu A.
    • Organizer
      The 18th Annual European Congress of Rheumatology - EULAR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] 3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation)2017

    • Author(s)
      Okano Takaichi, Saegusa Jun, Nishimura Keisuke, Ueda Yo, Sendo Sho, Takahashi Soshi, Nishida Miwa, Akashi Kengo, Onishi Akira, Morinobu Akio
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Glutamine metabolism plays a crucial role in the pathogenesis of rheumatoid arthritis.2016

    • Author(s)
      Takahashi S, Saegusa J, Naka I, Tsuda K, Okano T, Akashi K, Sendo S, Ueda Y, Onishi A, Kogata Y, Morinobu A.
    • Organizer
      American College of Rheumatology 80th Annual Scientific Meeting
    • Place of Presentation
      ワシントンDC、米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.2016

    • Author(s)
      Akashi K, Saegusa J, Sendo S, Nishimura K, Tsuda K, Naka I, Okano T, Takahashi S, Nishida M, Ueda Y, Morinobu A.
    • Organizer
      The 17th Annual European Congress of Rheumatology - EULAR 2016
    • Place of Presentation
      イギリス ロンドン
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] CD11b+Gr1dim cells, which are induced by GM-CSF produced by Th17 and group3 innate lymphoid cell, may facilitate the progression of pneumonitis in SKG mice.2016

    • Author(s)
      Sendo S, Saegusa J, Okano T, Takahashi S, Morinobu A.
    • Organizer
      American College of Rheumatology 80th Annual Scientific Meeting
    • Place of Presentation
      ワシントンDC、米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] 3-bromopyruvate ameliorates autoimmune arthritis by exerting a dual effect on both Th17 and Treg cell differentiation and dendritic cell activation.2016

    • Author(s)
      Okano T, Saegusa J,  Nishimura K, Takahashi S, Sendo S, Ueda Y, Onishi A, Morinobu A.
    • Organizer
      The 17th Annual European Congress of Rheumatology - EULAR 2016
    • Place of Presentation
      イギリス ロンドン
    • Year and Date
      2016-06-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] 3-bromopyruvate ameliorates autoimmune arthritis by exerting a dual effect on both Th17 and Treg cell differentiation and dendritic cell activation.2016

    • Author(s)
      Okano T, Saegusa J,  Nishimura K, Takahashi S, Sendo S, Ueda Y, Onishi A, Morinobu A.
    • Organizer
      The 17th Annual European Congress of Rheumatology
    • Place of Presentation
      ロンドン、英国
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Dual effect of 3-bromopyruvate on both Th17 and Treg cell differentiation and dendritic cell activation ameliorates autoimmune arthritis in mice.2016

    • Author(s)
      Okano T, Saegusa J, Nishimura K, Ueda Y, Sendo S, Takahashi S, Akashi K, Onishi A, Morinobu A.
    • Organizer
      American College of Rheumatology 80th Annual Scientific Meeting
    • Place of Presentation
      ワシントンDC、米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.2016

    • Author(s)
      Akashi K, Saegusa J, Sendo S, Nishimura K, Tsuda K, Naka I, Okano T, Takahashi S, Nishida M, Ueda Y, Morinobu A.
    • Organizer
      The 17th Annual European Congress of Rheumatology
    • Place of Presentation
      ロンドン、英国
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] MicroRNA-124 inhibits progression of adjuvant-induced arthritis in rats.2015

    • Author(s)
      Nakamachi Y, Ohnuma K, Uto K, Noguchi Y, Saegusa J, Kawano S.
    • Organizer
      The 16th Annual European Congress of Rheumatology - EULAR 2015
    • Place of Presentation
      イタリア ローマ
    • Year and Date
      2015-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Taurine as a biomarker for prediction of response to biologic therapy in rheumatoid arthritis.2015

    • Author(s)
      Takahashi S, Saegusa J, Naka I, Tsuda K, Okano T, Akashi K, Nishida M, Nishimura K, Sendo S, Ueda Y, Onishi A, Kogata Y, Kageyama G, Morinobu A.
    • Organizer
      American College of Rheumatology 79th Annual Scientific Meeting,
    • Place of Presentation
      アメリカ サンフランシスコ
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09525
  • [Presentation] Serum cytokine/chemokine profiles are useful for evaluating pathological conditions of rheumatoid arthritis and diagnosing anti-CCP antibody-negative patients.2013

    • Author(s)
      Uga H, Okazawa T, Miyamoto Y, Hasegawa T, Saegusa J, Tsuji G, Sendo S, Morinobu A, Kumagai S, Kurata H
    • Organizer
      American College of Rheumatology 77th Annual Scientific Meeting
    • Place of Presentation
      San Diego, CA
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Clinical Features of 127 patients with Behcet’s disease in Japan.2013

    • Author(s)
      Nishimura K, Saegusa J, Sendo S, Kogata Y, Kageyama G, Kawano S, Kumagai S, Morinobu A
    • Organizer
      American College of Rheumatology 77th Annual Scientific Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Immediate Early Response Gene X-1 is Over-expressed and Regulates Apoptosis and Cytokine Production in Rheumatoid Arthritis Synovial Fibroblasts2012

    • Author(s)
      Akio Morinobu, Masaaki Fujita, Shino Tanaka, Jun Saegusa and Shunichi Kumagai
    • Organizer
      第76回アメリカリウマチ学会
    • Place of Presentation
      Walter E Washington Convention Center(米国・ワシントン)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Serum Metabolomics As a Novel Diagnostic Approach for Systemic Lupus Erythematosus2012

    • Author(s)
      Saegusa J, Irino Y, Yoshida M, Tanaka S, Kogata Y, Kageyama G, Kawano S, Tsuji G, Kumagai S, Morinobu A
    • Organizer
      American College of Rheumatology 76th Annual ScientificMeeting(アメリカリウマチ学会)
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] Early Growth Response-1 (EGR-1) Controls Synoviocyte Apoptosis, and Its Expression Is Regulated by the Direct Binding of Fibroblast Growth Factor-1 (FGF1) or Insulin-Like Growth Factor-1 (IGF1) to Integrin αvβ32012

    • Author(s)
      Tanaka S, Saegusa J, Kawano S, Takada Y, Kumagai S, Morinobu A
    • Organizer
      American College of Rheumatology 76thAnnual Scientific Meeting(アメリカリウマチ学会)
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] 遺伝子多型に基づくサラゾスルファピリジン(SASP)の有効性の検討 関節リウマチの個別化医療2012

    • Author(s)
      萩原 慶明、辻 剛、千藤 荘、岡田 信彦、一瀬 良英、三枝 淳、熊谷 俊一
    • Organizer
      第59回日本臨床検査医学会 学術集会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Th17細胞はSKG関節炎モデルマウスの病態形成に関与する2012

    • Author(s)
      宮本 佳昭、田中 聡、池田 昌郁、宇賀 均、三枝 淳、森信 暁雄、熊谷 俊一、倉田 寛一
    • Organizer
      第22回日本サイトメトリー学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Th17細胞はSKG関節炎モデルマウスの病態形成に関与する2012

    • Author(s)
      宮本 佳昭、田中 聡、池田 雅郁、宇賀 均、三枝 淳、森信 暁雄、熊谷 俊一、倉田 寛一
    • Organizer
      第40回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 4つの表面マーカーを用いた新規分類法によるRAの病原性 CD4陽性T細胞の探求2012

    • Author(s)
      松木 郁親、三枝 淳、熊谷 俊一、森信 暁雄
    • Organizer
      第33回日本炎症・再生医学会
    • Place of Presentation
      ホテル日航福岡(福岡)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Immediate Early Response Gene X-1 is Over-expressed and Regulates Apoptosis and Cytokine Production in Rheumatoid Arthritis Synovial Fibroblasts2012

    • Author(s)
      Akio Morinobu, Jun Saegusa, Shino Tanaka, Shunichi Kumagai
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Regulatory and Pro-Inflammatory Properties of CD4+ T-Cell Subsets Defined by CD45RA, CCR7, CD27, and CD28 in Patients with Rheumatoid Arthritis2012

    • Author(s)
      Fumichika Matsuki, Jun Saegusa, Yoshiaki Miyamoto, Keisuke Nishimura, Shino Tanaka, Shunichi Kumagai, Akio Morinobu
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Regulatory and pro-inflammatory properties of CD4+ T-cell subsets defined by CD45RA, CCR7, CD27, and CD28 in patients with rheumatoid arthritis.2012

    • Author(s)
      Matsuki F, Saegusa J, Miyamoto Y, Misaki K, Kumagai S, Morinobu A
    • Organizer
      The 12th meeting of the Asian Society of Clinical Pathology and Laboratory Medicine (アジア臨床病理・臨床検査医学会)
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] 関節リウマチの病態に関与するCD4陽性T細胞サブセットの同定2012

    • Author(s)
      松木 郁親、三枝 淳、熊谷 俊一、森信 暁雄
    • Organizer
      第40回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 自己抗原SS-A/Ro52はBcl-2の発言を低下させることにより細胞のアポトーシスを促進する2012

    • Author(s)
      Jauharoh Siti Nur Aisyah、三枝 淳、笠木 伸平、杉山 大典、栗本 千代、中町 祐司、信原 由実子、杉本 健、森信 暁雄、熊谷 俊一、河野 誠司
    • Organizer
      第56回日本リウマチ学会総会・学術集会・第21回国際リウマチシンポジウムプログラム
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 生物学的製剤(TNF阻害薬)無効アダリムマブ(ADA)投与RA患者における抗アダリムマブ抗体(AAA)産生と血中ADA濃度および効果の関係(追加報告)2012

    • Author(s)
      辻 剛、河野 誠司、森信 暁雄、三枝 淳、杉山 大典、八木田 正人、旗智 さおり、波内 俊三、信原 由実子、中澤 隆、中村 知子、岡田 信彦、千藤 荘、熊谷 俊一
    • Organizer
      第56回日本リウマチ学会総会・学術集会・第21回国際リウマチシンポジウムプログラム
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Early Growth Response-1(EGR-1)Controls Synoviocyte Apoptosis, and Its Expression is Regulated by the Direct Binding of Fibroblast Growth Factor-1(FGF1)or Insulin-Like Growth Factor-1(IGF1) to Integrin αvβ3.2012

    • Author(s)
      Shino Tanaka, Jun Saegusa, Seiji Kawano, Yoshikazu Takada, Shunichi Kumagai and Akio Morinobu
    • Organizer
      第76回アメリカリウマチ学会
    • Place of Presentation
      Walter E Washington Convention Center(米国・ワシントン)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 関節リウマチの治療 DMARDs・NSAIDs(3)遺伝子多型に基づくサラゾスルファピリジン(SASP)の有効的使用法 関節リウマチの個別化医療2012

    • Author(s)
      熊谷 俊一、萩原 慶明、千藤 荘、岡田 信彦、杉山 大典、三枝 淳、辻 剛
    • Organizer
      第56回日本リウマチ学会総会・学術集会・第21回国際リウマチシンポジウムプログラム
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 4つの表面マーカーを用いた新規分類法によるRAの病原性CD4陽性T細胞の探求2012

    • Author(s)
      松木 郁親、三枝 淳、宮本 佳昭、三崎 健太、河野 誠司、熊谷 俊一、森信 暁雄
    • Organizer
      第56回日本リウマチ学会総会・学術集会・第21回国際リウマチシンポジウムプログラム
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Serum Metabolomics As a Novel Diagnostic Approach for Systemic Lupus Erythematosus.2012

    • Author(s)
      Jun Saegusa, Yasuhiro Irino, Masaru Yoshida, Shino Tanaka, Yoshinori Kogata, Goichi Kageyama, Seiji Kawano, Goh Tsuji, Shunichi Kumagai and Akio Morinobu
    • Organizer
      第76回アメリカリウマチ学会
    • Place of Presentation
      Walter E Washington Convention Center(米国・ワシントン)
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] Induces CD8a Positive Tolerogenic Dendritic Cells, Regulatory T Cells in SKG Mice, and Ameliorates the Severe Arthritis2011

    • Author(s)
      Misaki K, Morinobu A, Saegusa J, Kasagi S, Fujita M, Miyamoto Y, Matsuki F, Kumagai S. Trichostatin A
    • Organizer
      American College of Rheumatology 75th Annual ScientificMeeting(アメリカリウマチ学会)
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] 若手研究者が語るリウマチ性疾患の病態とシグナル伝達 インテグリンと増殖因子受容体の"two receptor model"2011

    • Author(s)
      三枝 淳
    • Organizer
      第55回日本リウマチ学会総会・学術集会・国際リウマチシンポジウム
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] The Sjogren's Syndrome-Related Autoantigen Ro52 Is a Pro-Apoptotic Molecule Upon Oxidative Stress2011

    • Author(s)
      Jauharoh SN, Kawano S, Saegusa J, Sugimoto T, Sugiyama D, Tokuno O, Kurimoto C, Nobuhara Y, Nakamachi Y, Ardianto B, Kumagai S
    • Organizer
      American College of Rheumatology 75th Annual ScientificMeeting(アメリカリウマチ学会)
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] インテグリンと増殖因子受容体の"two-receptor" model. 日本リウマチ学会カレントシンポジウム4 若手研究者が語るリウマチ性疾患の病態とシグナル伝達2011

    • Author(s)
      三枝 淳
    • Organizer
      第55回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] An integrin-binding-defective FGFR50E mutant promotes synoviocyte apoptosis by activating caspase-9 through modulation of Bcl-2 and Bim expression2010

    • Author(s)
      Saegusa J
    • Organizer
      International Workshop, The 54^<th> Annual general Assembly and Scientific Meeting of Japan College of Rheumatology
    • Place of Presentation
      神戸ポートピアホテル(兵庫県)(招待講演)
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis2010

    • Author(s)
      Saegusa J, Morinobu A, Kawano S, Kumagai S, Hsu DK, Chen HY, Yu L, Liu FT
    • Organizer
      International Congress of Immunology(国際免疫学会)
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] THE PROINFLAMMATORY ACTION OF PHOSPHOLIPASE A2 GROUP IIA IS MEDIATED THROUGH INTERACTION WITH INTEGRINS(ALPHA)V(BETA)3 AND (ALPHA)4(BETA)12010

    • Author(s)
      Saegusa J
    • Organizer
      Annual European Congress of Rheumatology EULAR 2010
    • Place of Presentation
      Rome, (Italy)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] Histone Deacetylase Inhibitor (HDAi) Ameliorates Chronic Arthritis in SKG Mice by Altering Conventional Dendritic Cells (cDCs) Phenotype into Tolerogenic DCs2010

    • Author(s)
      Misaki K, Morinobu A, Saegusa J, Miyamoto Y, Kasagi S, Kumagai S
    • Organizer
      American College of Rheumatology 74th Annual ScientificMeeting(アメリカリウマチ学会)
    • Place of Presentation
      Atlanta
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] インテグリン非結合FGF1はBcl-2関連蛋白を制御して滑膜細胞のアポトーシスを誘導する2010

    • Author(s)
      三枝淳
    • Organizer
      第54回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県)
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] Saegusa J, Fujita M, Morinobu A, Misaki K, Kawano S, Kumagai S2010

    • Author(s)
      Saegusa J, Fujita M, Morinobu A, Misaki K, Kawano S, Kumagai S
    • Organizer
      Annual general Assembly and Scientific Meeting of Japan College of Rheumatology(日本リウマチ学会総会・学術集会国際ワークショップ)
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] THE PROINFLAMMATORY ACTION OF PHOSPHOLIPASE A2 GROUP IIA IS MEDIATED THROUGH INTERACTION WITH INTEGRINS (ALPHA)v(BETA)3 AND (ALPHA)4(BETA)12010

    • Author(s)
      Saegusa J, Morinobu A, Kawano S, Takada Y, Kumagai S
    • Organizer
      Annual European Congress of Rheumatology, EULAR(欧州リウマチ学会)
    • Place of Presentation
      Rome
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis2010

    • Author(s)
      Saegusa J
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸ポートピアホテル(兵庫県)
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] HISTONE DEACETYLASE INHIBITOR (HDAI) AMELIORATES CHRONIC ARTHRITIS IN SKG MICE BY ALTERING CONVENTIONAL DENDRITIC CELLS (CDCS) PHENOTYPE INTO TOLEROGENIC DCS.2010

    • Author(s)
      Misaki K, Morinobu A, Saegusa J, Miyamoto Y, Kasagi S, Kumagai S
    • Organizer
      Annual European Congress of Rheumatology, EULAR(欧州リウマチ学会)
    • Place of Presentation
      Rome
    • Data Source
      KAKENHI-PROJECT-22790929
  • [Presentation] インテグリンはホスホリパーゼA2 group IIA(sPLA2-ILA)のレセプターとして働き炎症性シグナルを伝達する2009

    • Author(s)
      三枝淳
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Year and Date
      2009-04-25
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] インテグリンはホスホリパーゼA2 group IIA(sPLA2-IIA)のレセプターとして働き炎症性シグナルを伝達する2009

    • Author(s)
      三枝淳
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-25
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] An integrin binding- defective FGFR50E mutant promotes synoviocyte apoptosis by activating caspase-9 through modulation of Bcl-2 and Bim expression.2009

    • Author(s)
      J Saegusa
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] エタネルセプト(Eta. )投与下にリステリア髄膜脳炎を発症した関節リウマチ(RA)の一例2009

    • Author(s)
      西田美和、林宏樹、辻剛、三枝淳、杉本健、河野誠司、森信暁雄、熊谷俊一
    • Organizer
      第53回日本リウマチ学会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-23
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] An integrin binding-defective FGF^<R50E> mutant promotes synoviocyte apoptosis by activating caspase-9 through modulation of Bcl-2 and Bim expression2009

    • Author(s)
      三枝淳
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] Secretory Phospholipase A2 Group IIA Binds to Integrin avss3 and Induces Proinflammatory Signaling2009

    • Author(s)
      三枝淳
    • Organizer
      American College of Rheumatology, Annual Scientific Meeting
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] 急性期蛋白ホスホリパーゼA2 group IIAはインテグリンと結合して細胞内に炎症性シグナルを伝える2009

    • Author(s)
      三枝淳
    • Organizer
      第56回日本臨床検査医学会総会・学術集会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2009-08-27
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] Prevalence of Anti-Cyclic Citrullinated Peptide Antibody and Its Association with Smoking in General Population : a Cross Sectional Study.2009

    • Author(s)
      Kumagai S, Hayashi N, Kawano S, Sugiyama D, Nishimura K, Kasagi S, Saegusa J, Morinobou A
    • Organizer
      第75回米国リウマチ学会
    • Place of Presentation
      サンフランシスコ(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] エタネルセプト(Eta.)投与下にリステリア髄膜脳炎を発症した関節リウマチ(RA)の1例2009

    • Author(s)
      西田美和、林宏樹、辻剛、三枝淳、杉本健、河野誠司、森信暁雄、熊谷俊一
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Year and Date
      2009-04-26
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] Secretory Phospholipase A2 Group IIA Binds to Integrin avβ3 and Induces Proinflammatory Signaling.2009

    • Author(s)
      J Saegusa
    • Organizer
      第75回米国リウマチ学会
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] Secretory Phospholipase A2 Group Binds to Integrin v3 and Induces Proinflammatory Signaling.2009

    • Author(s)
      Saegusa J, Fujita M, Tanaka S, Morinobu A, Kawano S, Takada Y, Kumagai S
    • Organizer
      第75回米国リウマチ学会
    • Place of Presentation
      サンフランシスコ(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] Secretory Phospholipase A2 Group Binds to Integrin v3 and Induces Proinflammatory Signaling.2009

    • Author(s)
      Saegusa J, Fujita M, Tanaka S, Morinobu A, Kawano S, Takada Y, Kumagai S.
    • Organizer
      第75回米国リウマチ学会
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] Prevalence of Anti-Cyclic Citrullinated Peptide Antibody and Its Association with Smoking in General Population : a Cross Sectional Study.2009

    • Author(s)
      Kumagai S, Hayashi N, Kawano S, Sugiyama D, Nishimura K, Kasagi S, Saegusa J, Morinobu A.
    • Organizer
      第75回米国リウマチ学会
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-19390155
  • [Presentation] 急性期蛋白ホスホリパーゼA2 group IIAはインテグリンと結合して細胞内に炎症性シグナルを伝える2009

    • Author(s)
      三枝淳
    • Organizer
      第56回日本臨床検査医学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2009-08-27
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] ガレクチン-3は皮膚アレルギー性炎症の進行に重要な役割を果たしている2008

    • Author(s)
      三枝淳
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] Galectin-3 promotes activation of AKT and protects keratinocytes from apoptosis2008

    • Author(s)
      J Saegusa
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] ガレクチン-3は皮膚アレルギー性炎症の進行に重要な役割を果たしている2008

    • Author(s)
      三枝 淳
    • Organizer
      日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] Galectin-3 promotes activation of AKT and protects keratinocytes from apoptosis2008

    • Author(s)
      Saegusa J
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-20890126
  • [Presentation] シェーグレン症候群患者の唾液メタボロミクス

    • Author(s)
      蔭山 豪一, 三枝 淳, 田中 姿乃, 大西 輝, 古形 芳則, 森信 暁雄
    • Organizer
      第23回日本シェーグレン症候群学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2014-09-12 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 血清メタボロミクスによる全身性エリテマトーデスの新規バイオマーカーの探索

    • Author(s)
      三枝 淳, 河野 誠司, 辻 剛, 熊谷 俊一, 森信 暁雄
    • Organizer
      第61回日本臨床検査医学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-22 – 2014-11-25
    • Data Source
      KAKENHI-PROJECT-24591445
  • [Presentation] 自己免疫疾患のメタボローム解析の未来~新規バイオマーカーの同定と病態解明を目指して~

    • Author(s)
      三枝淳
    • Organizer
      日本臨床検査医学会 第57回近畿支部総会
    • Place of Presentation
      神戸
    • Year and Date
      2014-09-20 – 2014-09-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591445
  • 1.  KAWANO Seiji (20351512)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 29 results
  • 2.  MORINOBU Akio (10294216)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 75 results
  • 3.  NAKAMACHI Yuji (80379429)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 4.  KASAGI SHINPEI (80457051)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KUMAGAI Shunichi (00153346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  NISHIMURA Kunihiro (70397834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  中澤 隆 (40397831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  蔭山 豪一 (80631621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  籏智 さおり (70414117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  西村 啓佑 (20771497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  脇 大輔 (00914243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大西 輝 (60634269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  青井 貴之 (00546997)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAKADA Yoshikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 15.  Noguchi Yoriko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Onuma Kenichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  林 宏樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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