Miyoshi Goichi 三好悟一

Researcher Number	20519326
Other IDs	https://orcid.org/0000-0002-1872-6278
Affiliation (Current)	2026: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 群馬大学, 大学院医学系研究科, 教授 2017 – 2020: 東京女子医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Transformative Research Areas, Section (III) / Basic Section 49010:Pathological biochemistry-related / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 抑制ニューロン / 自閉スペクトラム症 / 回路発達 / 興奮抑制バランス / 自閉症 / 社会性行動 / 社会性 / FOXG1症候群 / 発症の臨界期 / 自閉症スペクトラム … More / 前頭前皮質 / 抑制回路発達 / 遺伝子量 / GABA細胞 / 神経発達障害 / 抑制回路 / 興奮抑制回路 / 脳波 / FOXG1 / コネクトーム / 神経活動 / 中間表現型 / 皮質発達 / 生後発達 / 臨界期 / 大脳皮質発生 / 細胞移動 / 皮質細胞移動 / 接線方向移動 / 放射状方向移動 / 皮質発生 / 放射状方向遊走 / 接線方向遊走 / 細胞遊走 / 大脳皮質 / 遺伝子制御 / 皮質場との連携 / 発生時計 / 回路形成 / 抑制 / 電気生理学 / 行動実験 / 興奮抑制 / FoxG1 / 疾患モデルマウス / 回路興奮抑制 Less

社会性機能創発を促す幼児期活発コアコネクトームの解明Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Gunma University
自閉スペクトラム症の生後発症臨界期における回路発達メカニズムの解明Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gunma University
ASD研究に変革をもたらす臨界期再構築戦略Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Gunma University
A study on ASD-related model animalsPrincipal Investigator
- Principal Investigator
  
  Miyoshi Goichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gunma University
  Tokyo Women's Medical University
皮質細胞の移動方向と連携した発生時計による分子制御機構の解明Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
自閉症病態にみられる社会性行動の構成的理解　～幼児期E/Iバランス仮説の検証Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
Analysis of novel ASD mouse modelsPrincipal Investigator
- Principal Investigator
  
  Miyoshi Goichi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Women's Medical University
GABA細胞発生時計による遺伝子「量」制御と皮質層の連携と構築Principal Investigator
- Principal Investigator
  
  三好悟一
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University

All 2025 2024 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Developmental regression of novel space preference in an autism spectrum disorder model is unlinked to GABAergic and social circuitry2025
- Author(s)
  Asano Hirofumi、Arai Masaya、Narita Aito、Kuroiwa Takayuki、Fukuchi Mamoru、Yoshimoto Yuhei、Oya Soichi、Miyoshi Goichi
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 18 Pages: 0-0
- DOI
  10.3389/fncel.2024.1513347
- Data Source
  KAKENHI-PUBLICLY-23H04211, KAKENHI-PROJECT-23K27374
[Journal Article] A novel quadrant spatial assay reveals environmental preference in mouse spontaneous and parental behaviors2024
- Author(s)
  Narita Aito、Asano Hirofumi、Kudo Hayato、Miyata Shigeo、Shutoh Fumihiro、Miyoshi Goichi
- Journal Title
  
  Neuroscience Research
  
  Volume: 209 Pages: 18-27
- DOI
  10.1016/j.neures.2024.08.002
- Data Source
  KAKENHI-PUBLICLY-23H04211, KAKENHI-PROJECT-23K27374
[Journal Article] Miyoshi G, Ueta Y, Yagasaki Y, Kishi Y, Fishell G, Machold RP, Miyata M2024
- Author(s)
  Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression level
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 121 Issue: 16 Pages: 0-0
- DOI
  10.1073/pnas.2317783121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19823, KAKENHI-PUBLICLY-22H04687, KAKENHI-PUBLICLY-23H04211, KAKENHI-ORGANIZER-20H05914, KAKENHI-PLANNED-20H05916, KAKENHI-PUBLICLY-23H04214, KAKENHI-PUBLICLY-24H01227, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K27374, KAKENHI-PROJECT-24K02020
[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period resulting in autism spectrum disorder-like phenotypes2021
- Author(s)
  Miyoshi Goichi、Ueta Yoshifumi、Natsubori Akiyo、Hiraga Kou、Osaki Hironobu、Yagasaki Yuki、Kishi Yusuke、Yanagawa Yuchio、Fishell Gord、Machold Robert P、Miyata Mariko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3773-3773
- DOI
  10.1038/s41467-021-23987-z
- NAID
  120007125060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04789, KAKENHI-PUBLICLY-19H05228, KAKENHI-PROJECT-21K15634, KAKENHI-PUBLICLY-20H05383, KAKENHI-PUBLICLY-21H00242, KAKENHI-PUBLICLY-21H05641, KAKENHI-PROJECT-20H03179, KAKENHI-PROJECT-19H03343, KAKENHI-PROJECT-16H06279, KAKENHI-ORGANIZER-20H05914, KAKENHI-PROJECT-20K21508, KAKENHI-PLANNED-20H05916
[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period for autism spectrum disorder-like phenotypes2021
- Author(s)
  Goichi Miyoshi, Yoshifumi Ueta, Akiyo Natsubori, Kou Hiraga, Hironobu Osaki, Yuki Yagasaki, Yusuke Kishi, Yuchio Yanagawa, Gordon J. Fishell, Robert P. Machold and Mariko Miyata
- Journal Title
  
  Nature Communications
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04789
[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period for autism spectrum disorder-like phenotypes2021
- Author(s)
  Goichi Miyoshi, Yoshifumi Ueta, Akiyo Natsubori, Kou Hiraga, Hironobu Osaki, Yuki Yagasaki, Yusuke Kishi, Yuchio Yanagawa, Gordon J. Fishell, Robert P. Machold and Mariko Miyata
- Journal Title
  
  Nature Communications
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05228
[Journal Article] Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network2019
- Author(s)
  Hou Pei-Shan、Miyoshi Goichi、Hanashima Carina
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-18
- DOI
  10.1038/s41467-019-11043-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06483, KAKENHI-PUBLICLY-19H05228, KAKENHI-PROJECT-19H03237, KAKENHI-PROJECT-17F17090
[Journal Article] Hierarchical genetic interactions between FOXG1 and LHX2 regulate the formation of the cortical hem in the developing telencephalon2017
- Author(s)
  Godbole Geeta、Shetty Ashwin S.、Roy Achira、D'Souza Leora、Chen Bin、Miyoshi Goichi、Fishell Gordon、Tole Shubha
- Journal Title
  
  Development
  
  Volume: 145 Issue: 1 Pages: 154583-154583
- DOI
  10.1242/dev.154583
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07102
[Patent] 自閉症の特徴を示すげっ歯類動物2018
- Inventor(s)
  三好悟一宮田麻理子
- Industrial Property Rights Holder
  三好悟一宮田麻理子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-092200
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K07102
[Presentation] ASDモデルにおける抑制ニューロン発達と社会性形成機構2025
- Author(s)
  三好悟一
- Organizer
  第19回自閉症学研究会（19th JCAR in SENDAI）
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] FOXG1症候群とその治療モデルマウスを用いた回路発達研究への取り組み2025
- Author(s)
  三好悟一
- Organizer
  レット症候群とその周辺疾患の臨床調査研究班公開シンポジウムin大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] あの時の○○が、今の研究者ライフにつながっている2025
- Author(s)
  三好悟一
- Organizer
  臨界期生物学　冬のワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] ASDモデルを用いた社会性発達における抑制ニューロンメカニズムの解明2024
- Author(s)
  三好悟一
- Organizer
  鹿児島神経科学鍋倉淳一先生特別講演会および研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] 自閉スペクトラム症につながる脳発達過程を理解する2024
- Author(s)
  三好悟一
- Organizer
  都医学研第3回都民講座
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] An Early Postnatal Critical Period for Social Behavior Circuit Development2024
- Author(s)
  三好悟一
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] An early postnatal critical period for ASD-related GABAergic circuit development2024
- Author(s)
  Goichi Miyoshi
- Organizer
  Gordon Research Conference, Neural Development
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04211
[Presentation] An early postnatal critical period for the development of inhibitory neurons in social circuit regulation2024
- Author(s)
  Goichi Miyoshi
- Organizer
  International Society for Developmental Neuroscience (ISDN)　2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04211
[Presentation] An Early Postnatal Critical Period for Social Behavior Circuit Development2024
- Author(s)
  三好悟一
- Organizer
  遺伝研研究会2024「哺乳類脳の機能的神経回路の構築メカニズム」
- Invited
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] An early postnatal critical period for the development of inhibitory neurons in social circuit2024
- Author(s)
  三好悟一
- Organizer
  International Society for Developmental Neuroscience (ISDN)　2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] An early postnatal critical period for ASD-related GABAergic circuit development2024
- Author(s)
  三好悟一
- Organizer
  Gordon Research Conference, Neural Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27374
[Presentation] 自閉スペクトラム症につながる脳発達過程を理解する2024
- Author(s)
  三好悟一
- Organizer
  都医学研第3回都民講座
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04211
[Presentation] An Early Postnatal Critical Period for Social Behavior Circuit Development2024
- Author(s)
  Goichi Miyoshi
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04211
[Presentation] FOXG1-dependent early juvenile critical period for autism-associated behavioral circuit2020
- Author(s)
  Goichi Miyoshi
- Organizer
  FOXG1 science symposium 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05228
[Presentation] FOXG1-dependent early juvenile critical period for autism-associated behavioral circuit2020
- Author(s)
  Goichi Miyoshi
- Organizer
  FOXG1 Science Symposium 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07362
[Presentation] FOXG1-dependent early juvenile critical period for autism-associated behavioral circuit2020
- Author(s)
  Goichi Miyoshi
- Organizer
  FOXG1 science symposium 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07102
[Presentation] FOXG1-dependent early juvenile critical period for autism-associated behavioral circuit2020
- Author(s)
  Goichi Miyoshi
- Organizer
  FOXG1 science symposium 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04789
[Presentation] FoxG1因子量による自閉症病態の発症機構2019
- Author(s)
  三好悟一
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PUBLICLY-19H05228
[Presentation] FoxG1因子量による自閉症病態の発症機構2019
- Author(s)
  三好悟一
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PUBLICLY-19H04789
[Presentation] FoxG1因子量による自閉症病態の発症機構2019
- Author(s)
  三好悟一
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-17K07102
[Presentation] ASD-linked gene FoxG1 controls inhibitory circuit development in a dose-dependent manner2018
- Author(s)
  Goichi Miyoshi
- Organizer
  45th Annual Meeting of the Society-for-Neuroscience,
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05775
[Presentation] Assembly of inhibitory circuitry by FoxG1, a gene associated with autism spectrum disorders2018
- Author(s)
  三好悟一
- Organizer
  The 41st Annual Meeting of the Japan Neuroscience Society
- Invited
- Data Source
  KAKENHI-PROJECT-17K07102
[Presentation] Gene-dosage dependent inhibitory circuit assembly and social behavior tuning by FoxG1, a transcription factor associated with ASD2017
- Author(s)
  Goichi Miyoshi
- Organizer
  Gordon Research Conference Inhibition in the CNS
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05775
[Presentation] Assembly of inhibitory circuitry by FoxG1, a gene associated with autism spectrum disorders2017
- Author(s)
  Goichi Miyoshi
- Organizer
  Society for Neuroscience Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07102
[Presentation] Assembly of inhibitory circuitry by FoxG1, a gene associated with autism spectrum disorders2017
- Author(s)
  Goichi Miyoshi
- Organizer
  44th Annual Meeting of the Society-for-Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05775

1. 花嶋かりな

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyoshi Goichi 三好 悟一

Research Projects

Research Products

Co-Researchers

社会性機能創発を促す幼児期活発コアコネクトームの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自閉スペクトラム症の生後発症臨界期における回路発達メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ASD研究に変革をもたらす臨界期再構築戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study on ASD-related model animalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

皮質細胞の移動方向と連携した発生時計による分子制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自閉症病態にみられる社会性行動の構成的理解 ～幼児期E/Iバランス仮説の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of novel ASD mouse modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GABA細胞発生時計による遺伝子「量」制御と皮質層の連携と構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Developmental regression of novel space preference in an autism spectrum disorder model is unlinked to GABAergic and social circuitry2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel quadrant spatial assay reveals environmental preference in mouse spontaneous and parental behaviors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Miyoshi G, Ueta Y, Yagasaki Y, Kishi Y, Fishell G, Machold RP, Miyata M2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period resulting in autism spectrum disorder-like phenotypes2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period for autism spectrum disorder-like phenotypes2021

Author(s)

Journal Title

Data Source

[Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period for autism spectrum disorder-like phenotypes2021

Author(s)

Journal Title

Miyoshi Goichi 三好悟一

自閉症病態にみられる社会性行動の構成的理解　～幼児期E/Iバランス仮説の検証Principal Investigator