SHIMOKAWA Chizu 下川千寿

Researcher Number	20529284
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 久留米大学, 医学部, 助教 2009 – 2011: Kurume University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Chemistry related to living body
Keywords	Principal Investigator 悪性腫瘍 / イソクエン酸デヒドロゲナーゼ(IDH) / 水酸化ペプチド分解酵素(PAL) / 水酸化ペプチド分解酵素(PAL) / ペプチドC末端水酸化酵素(PHM) / ペプチドC末端アミド化酵素(PAM) / 2-ヒドロキシグルタル酸(D2HG) / イソクエン酸デヒドロゲナーゼ(IDH)変異 / 構造生物学 / 酵素 … More / タンパク質 / 生体反応化学 / ペプチドホルモン / 金属酵素 / 亜鉛酵素 / 銅酵素 / PAL / PHM / PAM / 酵素化学 Less

ペプチドC末端アミド化酵素がIDH変異を伴う悪性腫瘍に及ぼす影響Principal Investigator
- Principal Investigator
  
  下川千寿
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kurume University
Investigation of the structure and reaction mechanisms of human peptidylglycineα-amidating monooxygenasePrincipal Investigator
- Principal Investigator
  
  SHIMOKAWA Chizu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kurume University

All 2011 2010 2009

All Journal Article Presentation

[Journal Article] Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae2011
- Author(s)
  N. Fujieda, M. Murata, S. Yabuta, T. Ikeda, C. Shimokawa, Y. Nakamura, Y. Hata, and S. Itoh
- Journal Title
  
  ChemBioChem
  
  Volume: 13(2) Pages: 193-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Reduction of oxaporphyrin ring of CO-bound α-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase2011
- Author(s)
  Hideaki Sato, Yuichiro Higashimoto, Hiroshi Sakamoto, Masakazu Sugishima, Chizu Shimokawa, Jiro Harada, Graham Palmer, Masato Noguchi
- Journal Title
  
  Journal of Inorganic Biochemistry
  
  Volume: 105 Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Reduction of oxaporphyrin ring of CO-boundα-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase2011
- Author(s)
  H. Sato, Y. Higashimoto, H. Sakamoto, M. Sugishima, C. Shimokawa, J. Harada, G. Palmer, and M. Noguchi
- Journal Title
  
  J. Inorg. Biochem
  
  Volume: 105(2) Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae2011
- Author(s)
  Nobutaka Fujieda, Michiaki Murata, Shintaro Yabuta, Takuya Ikeda, Chizu Shimokawa, Yukihiro Nakamura, Yoji Hata, Shinobu Itoh
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Issue: 2 Pages: 193-201
- DOI
  10.1002/cbic.201100609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] (Selected Paper) Resonance Raman Spectra of β-Diketiminatocopper(II) Complexes2010
- Author(s)
  Tomoko Miyazaki, Chizu Shimokawa Toshio Matsushita, Shinobu Itoh, Junji Teraoka
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 83 Pages: 1162-1169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Resonance Raman Spectra of β-Diketiminatocopper(II) Complexes2010
- Author(s)
  T. Miyazaki, C. Shimokawa, T. Matsushita, S. Itoh, and J. Teraoka
- Journal Title
  
  Bull. Chem. Soc. J
  
  Volume: 83(10) Pages: 193-201
- NAID
  10026699080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem : presence of a hydrogen-bond network on the distal side2009
- Author(s)
  H. Sato, M. Sugishima, H. Sakamoto, Y. Higashimoto, C. Shimokawa, K. Fukuyama, G. Palmer and M. Noguchi
- Journal Title
  
  Biochem. J
  
  Volume: 419(2) Pages: 339-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Journal Article] Crystal structure of rat haem oxygenase-1 in complex with ferrousverdohaem : presence of a hydrogen-bond network on the distal side2009
- Author(s)
  Hideaki Sato, Masakazu Sugishima, Hiroshi Sakamoto, Yuichiro Higashimoto, Chizu Shimokawa, Keiichi Fukuyama, Graham Palmer, Masato Noguchi
- Journal Title
  
  Biochemical Journal 419
  
  Pages: 339-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] ヒト由来アポ型アミド化酵素の金属再構成体を用いた反応解析2011
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  平成23年度日本生化学会九州支部例会
- Place of Presentation
  久留米大学旭町キャンパス,福岡
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] ヒト由来アポ型アミド化酵素の金属再構成体を用いた反応解析2011
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  平成23年度日本生化学会九州支部例会
- Place of Presentation
  久留米大学
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] Hinge欠損型NADPH-シトクロムP450還元酵素を用いたヘムオキシゲナーゼ反応と相互作用解析2010
- Author(s)
  杉島正一, 原田二朗, 佐藤秀明, 下川千寿, 原田沙織, 野口正人
- Organizer
  平成22年度日本生化学会九州支部例会
- Place of Presentation
  鹿児島大学郡元キャンパス,鹿児島
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] ペプチドアミド化反応における亜鉛および鉄の役割2010
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  日本化学会第90回春季年会
- Place of Presentation
  近畿大学本部キャンパス
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] The roles of zinc and iron ion in peptide amidation2010
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  2010環太平洋国際化学会議(Pacifichem2010)
- Place of Presentation
  ハワイコンベンションセンター
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] The roles of zinc and iron in peptide amidation2010
- Author(s)
  C. Shimokawa, S. Harada, Y. Higashimoto, H. Sato, M. Sugishima, and M. Noguchi
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies(Pacifichem2010)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] ペプチドアミド化反応における亜鉛および鉄イオンの役割2010
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学本部キャンパス,大阪
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] Peptidylamidoglycolate lyase 反応における亜鉛および鉄イオンの役割2009
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  第24回生体機能関連化学シンポジウム・第12回バイオテクノロジーシンポジウム
- Place of Presentation
  九州大学医系キャンパス
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] Ferrous a-verdoheme in complex with rat heme oxygenase-1.Its crystal stucture and electrochemistry, Heme oxygenases in biology and medicine2009
- Author(s)
  H. Sato, M. Sugishima, Y. Higashimoto, H. Sakamoto, C. Shimokawa, M. Noguchi
- Organizer
  The 6^<th> international congress on heme oxygenases
- Place of Presentation
  Miami Beach, Florida, USA
- Data Source
  KAKENHI-PROJECT-21750181
[Presentation] Peptidylamidoglycolate lyase反応における亜鉛および鉄イオンの役割2009
- Author(s)
  下川千寿, 原田沙織, 東元祐一郎, 佐藤秀明, 杉島正一, 野口正人
- Organizer
  第24回生体機能関連化学シンポジウム・第12回バイオテクノロジーシンポジウム
- Place of Presentation
  九州大学医系キャンパス,福岡
- Data Source
  KAKENHI-PROJECT-21750181

1. 杉島正一 (30379292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 田中剛 (90616575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMOKAWA Chizu 下川 千寿

Research Projects

Research Products

Co-Researchers

ペプチドC末端アミド化酵素がIDH変異を伴う悪性腫瘍に及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the structure and reaction mechanisms of human peptidylglycineα-amidating monooxygenasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae2011

Author(s)

Journal Title

Data Source

[Journal Article] Reduction of oxaporphyrin ring of CO-bound α-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase2011

Author(s)

Journal Title

Data Source

[Journal Article] Reduction of oxaporphyrin ring of CO-boundα-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase2011

Author(s)

Journal Title

Data Source

[Journal Article] Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (Selected Paper) Resonance Raman Spectra of β-Diketiminatocopper(II) Complexes2010

Author(s)

Journal Title

Data Source

[Journal Article] Resonance Raman Spectra of β-Diketiminatocopper(II) Complexes2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem : presence of a hydrogen-bond network on the distal side2009

Author(s)

Journal Title

Data Source

[Journal Article] Crystal structure of rat haem oxygenase-1 in complex with ferrousverdohaem : presence of a hydrogen-bond network on the distal side2009

Author(s)

Journal Title

Data Source

[Presentation] ヒト由来アポ型アミド化酵素の金属再構成体を用いた反応解析2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒト由来アポ型アミド化酵素の金属再構成体を用いた反応解析2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hinge欠損型NADPH-シトクロムP450還元酵素を用いたヘムオキシゲナーゼ反応と相互作用解析2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ペプチドアミド化反応における亜鉛および鉄の役割2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The roles of zinc and iron ion in peptide amidation2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The roles of zinc and iron in peptide amidation2010

Author(s)

SHIMOKAWA Chizu 下川千寿