Irie Tomohiko 入江智彦

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IRIE Tomohiko 入江智彦

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Researcher Number	20546551
Other IDs	https://orcid.org/0000-0002-8441-8417
Affiliation (Current)	2024: 北里大学, 医学部, 准教授 2024: 国立医薬品食品衛生研究所, 薬理部, 主任研究官
Affiliation (based on the past Project Information) *help	2012 – 2022: 国立医薬品食品衛生研究所, 薬理部, 主任研究官
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator CICR / イオンチャネル / アドレナリン受容体 / 非選択的陽イオンチャネル / 蝸牛神経核 / Ca依存性Kチャネル / Ca2+ドメイン / P/QタイプCav / Kv2 / SKチャネル … More / SK チャネル / Ca2+誘発性Ca2+放出 / eCB / DSE / CB1 / バースト発火 / BKチャネル / リアノジン受容体 / 神経細胞 / 活動電位 / カリウムチャネル / プルキンエ細胞 / 小脳失調症 / 小脳 … More Except Principal Investigator RNA sequence / Single cell / 分子メカニズム / 耳鳴り / 難聴 / 聴覚 / Single nucleus RNA‐seq / Single cell RNA‐Sequence Less

アドレナリン受容体による新規ナトリウム漏洩チャネルNALCNの調節機構解明Principal Investigator
- Principal Investigator
  
  入江智彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  National Institute of Health Sciences
分子・形態・電気生理統合アプローチによる言語音聴取発症の分子メカニズムの解明
- Principal Investigator
  
  相古千加
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of Toyama
A study of K(Ca) channels by using super-resolution fluorescence microscopyPrincipal Investigator
- Principal Investigator
  
  Irie Tomohiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  National Institute of Health Sciences
A study of ryanodine receptor-mediated modulation of spontaneous firings in neuronsPrincipal Investigator
- Principal Investigator
  
  Tomohiko Irie
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Institute of Health Sciences
A physiological study of KCNQ channel functions in the mammalian cerebellum.Principal Investigator
- Principal Investigator
  
  Irie Tomohiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute of Health Sciences
Kv3.3 channels harboring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar neuronsPrincipal Investigator
- Principal Investigator
  
  IRIE Tomohiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute of Health Sciences

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current2023
- Author(s)
  Takahashi K, Chen L, Sayama M, Wu M, Hayashi MK, Irie T, Ohwada T, Sato K
- Journal Title
  
  J Biol Chem
  
  Volume: 299 Issue: 1 Pages: 102793-102793
- DOI
  10.1016/j.jbc.2022.102793
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05963, KAKENHI-PROJECT-19K07295
[Journal Article] Valproic acid promotes differentiation of adipose tissue-derived stem cells to neuronal cells selectively expressing functional N-type voltage-gated Ca2+ channels2022
- Author(s)
  Satoh Azusa、Fujimoto Shinri、Irie Tomohiko、Suzuki Takehito、Miyazaki Yoko、Tanaka Kazuaki、Usami Makoto、Takizawa Tatsuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 589 Pages: 55-62
- DOI
  10.1016/j.bbrc.2021.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07295
[Journal Article] Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors2022
- Author(s)
  Irie Tomohiko、Yanase Yuta、Demizu Yosuke、Usami Makoto、Kikura-Hanajiri Ruri
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 150 Issue: 4 Pages: 233-243
- DOI
  10.1016/j.jphs.2022.09.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-22K06838, KAKENHI-PROJECT-19K07295
[Journal Article] Essential Role of Somatic Kv2 Channels in High-Frequency Firing in Cartwheel Cells of the Dorsal Cochlear Nucleus2021
- Author(s)
  Irie Tomohiko
- Journal Title
  
  eneuro
  
  Volume: 8 Issue: 3 Pages: ENEURO.0515-20.2021
- DOI
  10.1523/eneuro.0515-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07295
[Journal Article] A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice2021
- Author(s)
  Irie Tomohiko、Yamazaki Daiju、Kikura-Hanajiri Ruri
- Journal Title
  
  Forensic Toxicology
  
  Volume: 印刷中 Issue: 2 Pages: 474-480
- DOI
  10.1007/s11419-021-00571-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07295
[Journal Article] Loose coupling between SK and P/Q-type Ca2+ channels in cartwheel cells of the dorsal cochlear nucleus2019
- Author(s)
  Irie Tomohiko
- Journal Title
  
  Journal of Neurophysiology
  
  Volume: 122 Issue: 4 Pages: 1721-1727
- DOI
  10.1152/jn.00515.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07295, KAKENHI-PROJECT-16K08513
[Journal Article] Double-Nanodomain Coupling of Calcium Channels, Ryanodine Receptors, and BK Channels Controls the Generation of Burst Firing2017
- Author(s)
  Tomohiko Irie, Laurence O. Trussell
- Journal Title
  
  NEURON
  
  Volume: 96 Issue: 4 Pages: 856-870
- DOI
  10.1016/j.neuron.2017.10.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08513
[Journal Article] 電位依存性Ca2+チャネル，リアノジン受容体，電位/Ca2+活性化型K+チャネルからなる二重のCa2+ナノドメインはニューロンにおいてバースト発火を制御する2017
- Author(s)
  入江智彦 Laurence O. Trussell
- Journal Title
  
  First Author's
  
  Volume: - Pages: 141
- DOI
  10.7875/first.author.2017.141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08513
[Journal Article] Effects of 13 developmentally toxic chemicals on the migration of rat cephalic neural crest cells in vitro.2016
- Author(s)
  Usami M, Mitsunaga K, Miyajima A, Takamatu M, Kazama S, Irie T, Doi O, Takizawa T
- Journal Title
  
  Congenit Anom (Kyoto).
  
  Volume: 56(2) Issue: 2 Pages: 52-59
- DOI
  10.1111/cga.12121
- NAID
  130008079222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860154, KAKENHI-PROJECT-26450451
[Journal Article] A synthetic cannabinoid MAM-2201 potently suppresses synaptic transmission via activation of presynaptic CB1 receptors and reduces synaptically-evoked Intracellular Ca2+ transients in cerebellar Purkinje cells.2015
- Author(s)
  Irie T, Kikura-Hanajiri R, Usami M, Uchiyama N, Goda Y, Sekino Y.
- Journal Title
  
  Neuropharmacology
  
  Volume: xxx Pages: 1-13
- DOI
  10.1016/j.neuropharm.2015.02.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860154
[Journal Article] Proteomic analysis of ethanol-induced embryotoxicity in cultured post-implantation rat embryos.2014
- Author(s)
  Usami M, Mitsunaga K, Irie T, Miyajima A, Doi, O.
- Journal Title
  
  The Journal of Toxicological Sciences.
  
  Volume: 39 Pages: 285-292
- NAID
  130004903990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790230
[Journal Article] Proteomic analysis of ethanol-induced embryotoxicity in cultured post-implantation rat embryos2014
- Author(s)
  Usami M, Mitsunaga K, Irie T, Miyajima A, Doi O
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: vol 39 Pages: 285-292
- NAID
  130004903990
- URL
  https://www.jstage.jst.go.jp/article/jts/39/2/39_285/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790230
[Journal Article] Simple in vitro migration assay for neural crest cells and the opposite effects of all-trans-retinoic acid on cephalic- and trunk-derived cells.2014
- Author(s)
  Usami M, Mitsunaga K, Irie T, Miyajima A, Doi O.
- Journal Title
  
  Congenit Anom
  
  Volume: 54 Issue: 3 Pages: 184-188
- DOI
  10.1111/cga.12059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860154
[Journal Article] Various definitions of reproductive indices: a proposal for combined use of brief definitions.2014
- Author(s)
  Usami M, Mitsunaga K, Irie T, Nakajima M.
- Journal Title
  
  Congenital Anomalies
  
  Volume: 54（１） Issue: 1 Pages: 67-68
- DOI
  10.1111/cga.12036
- NAID
  50009196996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790230
[Journal Article] Proteomic analysis of ethanol-induced embryotoxicity in cultured post-implantation rat embryos.2014
- Author(s)
  Usami M, Mitsunaga K, Irie T, Miyajima A, Doi O.
- Journal Title
  
  J Toxicol Sci
  
  Volume: 39 Pages: 285-292
- NAID
  130004903990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860154
[Journal Article] Kv3.3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells.2014
- Author(s)
  Irie T, Matsuzaki Y, Sekino Y, and Hirai H
- Journal Title
  
  The Journal of Physiology.
  
  Volume: 592(Pt 1) Issue: 1 Pages: 229-247
- DOI
  10.1113/jphysiol.2013.264309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790230
[Journal Article] Kv3.3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells2014
- Author(s)
  Irie T, Matsuzaki Y, Sekino Y, and Hirai H
- Journal Title
  
  The Journal of Physiology
  
  Volume: 592(Pt 1) Pages: 229-247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 細胞体に存在するKv2チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である.2023
- Author(s)
  入江智彦
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06838
[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2023
- Author(s)
  入江智彦
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] 細胞体に存在するKv2チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である.2022
- Author(s)
  入江智彦
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-22K06838
[Presentation] Sodium leak channel NALCN underlies noradrenergic modulation of cartwheel cells of DCN.2022
- Author(s)
  Tenzin Ngodup, Tomohiko Irie, Laurence O．Trussell
- Organizer
  Neuroscience 2022, 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06838
[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2022
- Author(s)
  入江智彦
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2022
- Author(s)
  入江智彦
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] Sodium Leak Channel NALCN Underlies Noradrenergic Modulation of Cartwheel Interneurons of the Cochlear Nucleus.2022
- Author(s)
  Tenzin Ngodup, Tomohiko Irie, Sean Elkins, Laurence O．Trussell
- Organizer
  ARO 46th annual midwinter meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06838
[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2021
- Author(s)
  入江智彦
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] P/Q-タイプCa2+チャネル、リアノジン受容体、BKチャネルからなる2重Ca2+ナノドメインにより、バースト発火が調節される2020
- Author(s)
  入江智彦
- Organizer
  第93回　日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Loose coupling between SK and P/Q-type Ca2+ channels in cartwheel cells of the dorsal cochlear nucleus2020
- Author(s)
  Tomohiko Irie
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Loose coupling between SK and P/Q-type Ca2+ channels in cartwheel cells of the dorsal cochlear nucleus2020
- Author(s)
  Tomohiko Irie
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] Loose Coupling Between SK and P/Q-type Ca2+ Channels in Cartwheel Cells of the Dorsal Cochlear Nucleus2020
- Author(s)
  Tomohiko Irie
- Organizer
  ARO 43rd annual midwinter meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] P/Q-タイプCa2+チャネル、リアノジン受容体、BKチャネルからなる2重Ca2+ナノドメインにより、バースト発火が調節される2020
- Author(s)
  入江智彦
- Organizer
  第93回　日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] Loose Coupling Between SK and P/Q-type Ca2+ Channels in Cartwheel Cells of the Dorsal Cochlear Nucleus2020
- Author(s)
  Tomohiko Irie
- Organizer
  ARO 43rd annual midwinter meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] Intracellular Ca2+ source for SK channels in cartwheel cells of the mouse dorsal cochlear nucleus.2019
- Author(s)
  Tomohiko Irie
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-19K07295
[Presentation] Intracellular Ca2+ source for SK channels in cartwheel cells of the mouse dorsal cochlear nucleus.2019
- Author(s)
  Tomohiko Irie
- Organizer
  第9回アジア・オセアニア生理学会連合大会（FAOPS2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Intracellular Ca2+ source for SK channels in cartwheel cells of the mouse dorsal cochlear nucleus.2019
- Author(s)
  Tomohiko Irie
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Double nanodomain coupling of P/Q-type calcium channels, ryanodine receptors and BK channels controls generation of burst firing2018
- Author(s)
  Tomohiko Irie, Laurence O Trussell
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Double nanodomain coupling of calcium channels, ryanodine receptors and BK channels controls generation of burst firing2018
- Author(s)
  Tomohiko Irie, Laurence O. Trussell
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] Double nanodomain coupling of calcium channels, ryanodine receptors and BK channels controls generation of burst firing2017
- Author(s)
  Tomohiko Irie, Laurence O. Trussell
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08513
[Presentation] 脊髄小脳変性症13 型における変異型Kv3.3 チャネルは、培養小脳プルキンエ細胞において細胞死と興奮性変化を引き起こす2013
- Author(s)
  入江智彦、松崎泰教、関野祐子、平井宏和
- Organizer
  日本生理学会
- Place of Presentation
  タワーホール船橋（東京都）
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 脊髄小脳変性症にみられる変異型Kv3.3チャネルは,培養小脳プルキンエ細胞において細胞死と興奮性変化を引き起こす2013
- Author(s)
  入江智彦,松崎泰教,関野祐子,平井宏和
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] ドコサヘキサエン酸によるアストロサイトグルタミン酸トランスポーターEAAT2機能増強2013
- Author(s)
  高橋華奈子,入江智彦,関野祐子,佐藤薫
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 脊髄小脳変性症13型における変異型Kv3.3チャネルは、培養小脳プルキンエ細胞において細胞死と興奮性変化を引き起こす2013
- Author(s)
  入江智彦,松崎泰教,関野祐子,平井宏和
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 発生毒性物質がラット神経堤細胞の遊走に及ぼす影響に関する研究2013
- Author(s)
  宇佐見誠,満長克祥,入江智彦,宮島敦子,土井守
- Organizer
  第53回日本先天異常学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 脊髄小脳変性症にみられる変異型Kv3.3チャネルは、培養小脳プルキンエ細胞において細胞死と興奮性変化を引き起こす2013
- Author(s)
  入江智彦　松崎泰教　関野祐子　平井宏和
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 光学測定法によるマウス扁桃体外側核の神経応答に対するカンナビノイド類の作用の解析2013
- Author(s)
  原宏士朗,藤枝智美,入江智彦,三輪秀樹,岡淳一郎,白尾智明,花尻(木倉)瑠理,合田幸広,栗原正明,関野祐子
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] Kv3.3チャネルのミスセンス変異は培養小脳プルキンエ細胞において細胞死と興奮性変化を引き起こす2012
- Author(s)
  入江智彦、松崎泰教、関野祐子、平井宏和
- Organizer
  日本神経科学学会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] グルタミン酸トランスポーターEAAT2機能調節機構の解析ツールとしてのエピトープ標識EAAT2の開発2012
- Author(s)
  高橋華奈子、入江智彦、関野祐子, 佐藤薫
- Organizer
  第14回応用薬理研究会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] Missense mutation in Kv3.3 channel causes cell death and impairs neuronal excitability of cultured cerebellar Purkinje cells2012
- Author(s)
  入江智彦,松崎泰教,関野祐子,平井宏和
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24790230
[Presentation] 新規違法ドラッグMAM-2201はCB1受容体を介して神経伝達を強力に抑制し，複雑スパイク誘発性の細胞内Ca2+上昇を減弱させる
- Author(s)
  入江智彦, 花尻（木倉）瑠理, 宇佐見誠, 内山奈穂子, 合田幸広, 関野祐子
- Organizer
  生理研研究会「シナプス・神経ネットワークの機能ダイナミクス」
- Place of Presentation
  生理学研究所（愛知県）
- Year and Date
  2014-12-02 – 2014-12-03
- Data Source
  KAKENHI-PROJECT-26860154
[Presentation] 培養ラット胚におけるバルプロ酸による発生毒性のプロテオミクス解析
- Author(s)
  宇佐見誠，高松美奈，風間崇吾，満長克祥，入江智彦，宮島敦子，土井守，滝沢達
- Organizer
  第54回日本先天異常学会学術集会
- Place of Presentation
  麻布大学（神奈川県）
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-26860154
[Presentation] 新規違法ドラッグMAM-2201はCB1受容体を介して神経伝達を強力に抑制し，複雑スパイク誘発性の細胞内Ca2+上昇を減弱させる
- Author(s)
  入江智彦, 花尻（木倉）瑠理, 宇佐見誠, 内山奈穂子, 合田幸広, 関野祐子
- Organizer
  Neuro2014
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26860154

1. 伊藤哲史 (90334812)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. 相古千加 (10523889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HAYASHI Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Irie Tomohiko 入江 智彦

IRIE Tomohiko 入江 智彦

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アドレナリン受容体による新規ナトリウム漏洩チャネルNALCNの調節機構解明Principal Investigator

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分子・形態・電気生理統合アプローチによる言語音聴取発症の分子メカニズムの解明

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A study of K(Ca) channels by using super-resolution fluorescence microscopyPrincipal Investigator

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A study of ryanodine receptor-mediated modulation of spontaneous firings in neuronsPrincipal Investigator

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A physiological study of KCNQ channel functions in the mammalian cerebellum.Principal Investigator

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Kv3.3 channels harboring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar neuronsPrincipal Investigator

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[Journal Article] Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current2023

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[Journal Article] Valproic acid promotes differentiation of adipose tissue-derived stem cells to neuronal cells selectively expressing functional N-type voltage-gated Ca2+ channels2022

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[Journal Article] Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors2022

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[Journal Article] Essential Role of Somatic Kv2 Channels in High-Frequency Firing in Cartwheel Cells of the Dorsal Cochlear Nucleus2021

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[Journal Article] A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice2021

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[Journal Article] Loose coupling between SK and P/Q-type Ca2+ channels in cartwheel cells of the dorsal cochlear nucleus2019

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[Journal Article] Double-Nanodomain Coupling of Calcium Channels, Ryanodine Receptors, and BK Channels Controls the Generation of Burst Firing2017

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[Journal Article] 電位依存性Ca2+チャネル，リアノジン受容体，電位/Ca2+活性化型K+チャネルからなる二重のCa2+ナノドメインはニューロンにおいてバースト発火を制御する2017

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Irie Tomohiko 入江智彦

IRIE Tomohiko 入江智彦

[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2023

[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2022

[Presentation] 細胞体に存在するKv2 チャネルは背側蝸牛神経核カートホイール細胞の高頻度発火に重要である．2022