Hasegawa Koichi 長谷川孝一

… Alternative Names

長谷川孝一ハセガワコウイチ

HASEGAWA Koichi 長谷川孝一

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Researcher Number	20546783
Other IDs
Affiliation (Current)	2022: 島根大学, 学術研究院医学・看護学系, 講師
Affiliation (based on the past Project Information) *help	2021: 島根大学, 学術研究院医学・看護学系, 講師 2015: 大阪大学, 蛋白質研究所, 助教 2009 – 2015: Osaka University, たんぱく質研究所, 助教 2010 – 2012: 大阪大学, 蛋白質研究所, 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator エネルギー代謝 / アセチル化 / 視床下部 / 脳神経疾患 / 摂食 / 肥満 / 体温調節 / 神経科学 / 発生、分化 / 脳、神経 … More / 脳・神経 / Sirt1 / ミトコンドリア / 神経変性疾患 / PGC-1alpha / Necdin / パーキンソン病 / ニューロン / 神経保護 / ROS / 神経発生 / 軸索起始部 / 核膜複合体 / 核 / 軸索 / 可塑性 / i-GONAD / LINC … More Except Principal Investigator Necdin / エネルギー代謝 / 蛋白質ネットワーク / Sirt1 / Fox01 / SMC5/ 6複合体 / DNA修復 / 哺乳類ニューロン / FoxO1 / SMC5/6複合体 / 視床下部 / Sirtl / FoxOl / アセチル化 / SMC5 / 6複合体 / NSE3 / ニューロン / 生存能 / ミトコンドリア / 神経変性疾患 / PGC-1α / 遺伝子変異マウス / パーキンソン病モデル / 遺伝子導入 / ユビキチン化 / パーキンソン病 / 転写因子 / 活性酸素種 / 酸化ストレス / 翻訳後修飾 / SUMO化 / 立体構造予測 Less

Elucidation of the control system of axon initial segment starting from the nucleusPrincipal Investigator
- Principal Investigator
  
  長谷川孝一
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Shimane University
Regulation of mitochondrial biogenesis and function by necdin-Sirt1 complexPrincipal Investigator
- Principal Investigator
  
  Hasegawa Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Strengthening mechanism of neuronal vitality by necdin
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Regulation of energy metabolism by necdin-Sirt1 complexPrincipal Investigator
- Principal Investigator
  
  HASEGAWA Koichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Mechanisms maintaining neuronal survival via necdin-centered protein interaction networks
- Principal Investigator
  
  YOSHIKAWA Kazuaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Regulation of transcription factors and neuronal development by necdin-Sirt1 complexPrincipal Investigator
- Principal Investigator
  
  HASEGAWA Koichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

All 2022 2021 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Molecular mechanisms regulating the spatial configuration of neurites.2022
- Author(s)
  Hasegawa K and Kuwako K
- Journal Title
  
  Seminars in Cell and Developmental Biology
  
  Volume: -
- DOI
  10.1016/j.semcdb.2022.02.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22476, KAKENHI-PROJECT-20H03352, KAKENHI-PROJECT-21K20692
[Journal Article] Vascularization of human brain organoids.2021
- Author(s)
  Matsui TK, Tsuru Y, Hasegawa K, Kuwako KI
- Journal Title
  
  Stem Cells
  
  Volume: 0 Pages: 0-0
- DOI
  10.1002/stem.3368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22476, KAKENHI-PROJECT-20H03352, KAKENHI-PROJECT-21K20692
[Journal Article] Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells2016
- Author(s)
  Izumi Fujimoto, Koichi Hasegawa, Kazushiro Fujiwara, Masashi Yamada and Kazuaki Yoshikawa
- Journal Title
  
  Cellular Signalling
  
  Volume: 28 Pages: 94-107
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830053
[Journal Article] Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults2016
- Author(s)
  Hasegawa, K., Yasuda, T., Shiraishi, C., Fujiwara, K., Przedborski, S., Mochizuki, H., Yoshikawa, K.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Pages: 10943-10943
- DOI
  10.1038/ncomms10943
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830047, KAKENHI-PROJECT-25830053, KAKENHI-PROJECT-24300134
[Journal Article] Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells2016
- Author(s)
  Fujimoto, I., Hasegawa, K., Fujiwara, K., Yamada, M., Yoshikawa, K.
- Journal Title
  
  Cell Signal.
  
  Volume: 28 Pages: 94-107
- DOI
  10.1016/j.cellsig.2015.11.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830047, KAKENHI-PROJECT-25440047, KAKENHI-PROJECT-24300134
[Journal Article] Necdin Promotes Ubiquitin-Dependent Degradation of PIAS1 SUMO E3 ligase2014
- Author(s)
  Gur, I., Fujiwara, K., Hasegawa, K., Yoshikawa, K.
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- DOI
  10.1371/journal.pone.0099503
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-25830053, KAKENHI-PROJECT-26830047
[Journal Article] Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex.2014
- Author(s)
  Minamide, R., Fujiwara, K., Hasegawa, K., Yoshikawa, K.
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- DOI
  10.1371/journal.pone.0084460
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-24890104, KAKENHI-PROJECT-25830053
[Journal Article] Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.2013
- Author(s)
  Huang, Z., Fujiwara, K., Minamide, R., Hasegawa, K., Yoshikawa, K.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 33 Pages: 10362-10373
- DOI
  10.1523/jneurosci.5682-12.2013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-24890104, KAKENHI-PROJECT-25830053
[Journal Article] Necdin Controls Foxo1 Acetylation in Hypothalamic Arcuate Neurons to Modulate the Thyroid Axis2012
- Author(s)
  Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 32 Pages: 5562-5572
- DOI
  10.1523/jneurosci.0142-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300138, KAKENHI-PROJECT-23700445
[Journal Article] Necdin Controls Proliferation of White Adipocyte Progenitor Cells2012
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Tsuyoshi Ohkumo, Hiroyuki Miyoshi, Yu-Hua Tseng and Kazuaki Yoshikawa
- Journal Title
  
  PLoS ONE
  
  Volume: Vol. 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700445
[Journal Article] Necdin controls proliferation of white adipocyte progenitor cells2012
- Author(s)
  Fujiwara K, Hasegawa K, Ohkumo T, Miyoshi H, Tseng Y-H, Yoshikawa K
- Journal Title
  
  PLoS One
  
  Volume: 7(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300138
[Journal Article] Necdin controls Foxol acetylation in hypothalamic arcuate neurons to modulate the thyroid axis2012
- Author(s)
  Hasegawa, K., Kawahara, T., Fujiwara, K., Shimpuku, M., Sasaki, T., Kitamura, T., Yoshikawa, K.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 32 Pages: 5562-5572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300134
[Journal Article] Necdin controls proliferation of white adipocyte progenitor cells2012
- Author(s)
  Fujiwara, K., Hasegawa, K., Ohkumo, T., Miyoshi, H., Tseng, Y. H., Yoshikawa, K.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300134
[Journal Article] Yu-Hua Tseng and Kazuaki Yoshikawa, NecdinControls Proliferation of White Adipocyte Progenitor Cells2012
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Tsuyoshi Ohkumo, Hiroyuki Miyoshi
- Journal Title
  
  PLoS ONE
  
  Volume: 7(1)
- DOI
  10.1371/journal.pone.0030948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700445
[Journal Article] Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus2011
- Author(s)
  Aizawa T, Hasegawa K, Ohkumo T, Haga S, Ikeda K, Yoshikawa K
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 122-129
- DOI
  10.1111/j.1349-7006.2010.01775.x
- NAID
  10029288727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300138
[Journal Article] Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus2010
- Author(s)
  Takako Aizawa*, Koichi Hasegawa*, Tsuyoshi Ohkumo, Seiichi Haga, Kazuhiko Ikeda, Kazuaki Yoshikawa
- Journal Title
  
  Cancer Science 102(1)
  
  Pages: 122-129
- NAID
  10029288727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890123
[Journal Article] Necdin Promotes Tangential Migration of Neocortical Interneurons from Basal Forebrain2010
- Author(s)
  Takaaki Kuwajima*, Koichi Hasegawa*, Kazuaki Yoshikawa
- Journal Title
  
  The Journal of Neuroscience 30(10)
  
  Pages: 3709-3714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890123
[Journal Article] Necdin promotes tangential migration of neocortical interneurons from basal forebrain2010
- Author(s)
  Kuwajima T, Hasegawa K, Yoshikawa K
- Journal Title
  
  J Neurosci
  
  Volume: 30 Pages: 3709-3714
- DOI
  10.1523/jneurosci.5797-09.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] 核膜複合体LINCは軸索起始部の可塑性を制御する2022
- Author(s)
  長谷川孝一、松井健、近藤純平、荘司静香、濱徳行、桑子賢一郎
- Organizer
  第99回日本生理学大会
- Data Source
  KAKENHI-PROJECT-21K20692
[Presentation] 神経の極性と可塑性に関連する軸索起始部における核-細胞骨格結合タンパク質Nesprin-1の解析2021
- Author(s)
  長谷川孝一、松井健、近藤純平、石原朋郎、桑子賢一郎
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K20692
[Presentation] Necdin promotes mitochondrial biogenesis to prevent neurodegeneration in experimental Parkinson’s disease2015
- Author(s)
  Koichi Hasegawa, Toru Yasuda, Chinatsu Shiraishi, Kazushiro Fujiwara, Hideki Mochizuki, Kazuaki Yoshikawa
- Organizer
  Neuroscience 2015 45th Annual Meeting
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdin downregulates EGFR signaling in cortical neural precursor cells to suppress gliogenesis2015
- Author(s)
  Fujimoto I, Hasegawa K, Fujiwara K, Yoshikawa K
- Organizer
  Neuroscience 2015, ociety for Neuroscience
- Place of Presentation
  Chicago（USA)
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdin downregulates EGFR signaling in cortical neural precursor cells to suppress gliogenesis2015
- Author(s)
  Izumi Fujimoto, Koichi Hasegawa, Kazushiro Fujiwara, Kazuaki Yoshikawa
- Organizer
  Neuroscience 2015 45th Annual Meeting
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] 神経前駆細胞におけるNecdinによる上皮成長因子受容体シグナルの制御機構2015
- Author(s)
  藤本泉, 長谷川孝一, 藤原一志郎, 吉川和明
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Promotion of neuronal mitochondrial biogenesis by necdin: Neuroprotection in experimental Parkinsonism (Necdinによるニューロン内ミトコンドリア生合成の促進：実験的パーキンソンニズムにおける神経保護)2015
- Author(s)
  吉川和明、長谷川孝一、安田徹、望月秀樹
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdin promotes mitochondrial biogenesis to prevent neurodegeneration in experimental Parkinson's disease2015
- Author(s)
  Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Mochizuki H, Yoshikawa K
- Organizer
  Neuroscience 2015, Society for Neuroscience
- Place of Presentation
  Chicago（USA)
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] ニューロン分化におけるNecdinによるRanGAP1のSUMO化制御2015
- Author(s)
  藤原一志郎, 長谷川孝一, 吉川和明
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Promotion of neuronal mitochondiral biogenesis by necdin: Neuroprotection in experimental Parkinsonism2015
- Author(s)
  吉川和明, 長谷川孝一, 安田徹, 望月秀樹
- Organizer
  第３８回　日本神経科学会大会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-07-29
- Invited
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdin regulates RanGAP1 sumoylation during neuronal differentiation2014
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  Neuroscience 2014 44th Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center (Washington DC)
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdin promotes mitochondrial function in neurons: neuroprotection in Parkinson’s disease models (Necdinによるニューロン内ミトコンドリア機能の促進：パーキンソン病モデルにおける神経保護作用)2014
- Author(s)
  長谷川孝一、安田徹、白石千夏、藤原一志郎、望月秀樹、吉川和明
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館　奈良県新公会堂（奈良）
- Year and Date
  2014-09-30
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdinによる上皮成長因子受容体シグナルの制御機構2014
- Author(s)
  藤本泉、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館（京都）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdin suppresses PIAS1 SUMO E3 ligase activity by promoting ubiquitin-dependent degradation2013
- Author(s)
  Ibrahim Gur, Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] NecdinによるRanGAP1のSUMO化制御2013
- Author(s)
  藤原一志郎、長谷川孝一、吉川和明
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] 哺乳類ニューロンのDNA修復におけるNecdinの関与2012
- Author(s)
  瀬戸口良、長谷川孝一、三澤昭博、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] In vitro SUMO化反応系によるNecdinのSUMO修飾解析2012
- Author(s)
  藤原一志郎、長谷川孝一、江連徹、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア生合成の促進2012
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] In vitro SUMO化反応系によるNecdinのSUMO修飾解析2012
- Author(s)
  藤原一志郎、長谷川孝一、江連徹、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(招待講演)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] 視床下部Necdinによるエネルギー代謝関連因子の調節2012
- Author(s)
  長谷川孝一
- Organizer
  大阪大学蛋白質研究所セミナー「エネルギー代謝制御の分子機構」
- Place of Presentation
  大阪
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin suppresses preadipocyte proliferation to prevent adipocyte hyperplasia Rare Syndromic Body Fat Disorders: What Can They Teach Us?2012
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikaw
- Organizer
  National Institutes of Health
- Place of Presentation
  Bethesda Maryland USA
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] 哺乳類ニューロンのDNA修復におけるNecdinの関与2012
- Author(s)
  瀬戸口良、長谷川孝一、三津昭博、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(招待講演)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdin suppresses preadipocyte proliferation to prevent adipocyte hyherplasia2012
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  Rare Syndromic Body Fat Disorders: What Can They Teach Us?
- Place of Presentation
  National Institutes of Health, Bethesda Maryland USA
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア生合成の促進2012
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(招待講演)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdin suppresses proliferation of white adipocyte progenitor2011
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  Stem Cells in Development and Disease 2011
- Place of Presentation
  Berlin Germany
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Interaction between necdin and HIF-2alpha in neural stem cells2011
- Author(s)
  黄振宇、長谷川孝一、吉川和明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin forms multiprotein complexes with Smc5/6 components in mammalian brain2011
- Author(s)
  柏木裕呂樹、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  山代温泉　瑠璃光（石川）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin forms multiprotein complexes with Smc5/6 components in mammalian brain(Necdinは哺乳類脳においてSmc5/6構成要素と多蛋白質複合体を形成する)2011
- Author(s)
  柏木裕呂樹、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Interaction between necdin and HIF-2alpha in neural stem cells2011
- Author(s)
  黄振宇、長谷川孝一、吉川和明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin regulates proliferation of postnatal neural stem cells in mouse forebrain2011
- Author(s)
  橋長秀典、長谷川孝一、吉川和明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdinは哺乳類脳においSmc5/ 6構成要素と多蛋白質複合体を形成する2011
- Author(s)
  柏木裕呂樹、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin suppresses proliferation of white adipocyte progenitor2011
- Author(s)
  Kazushiro Fujiwara, Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  Stem Cells in Development and Disease 2011 Max Delbruck Center
- Place of Presentation
  Berlin Germany
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Hypothalamic necdin regulates thyroid hormone-mediated energy expenditure2011
- Author(s)
  白石千夏、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  山代温泉　瑠璃光（石川）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin regulates proliferation of postnatal neural stem cells in mouse forebrain2011
- Author(s)
  橋長秀典、長谷川孝一、吉川和明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Hypothalamic necdin regulates thyroid hormone-mediated energy expenditure(視床下部におけるNecdinは甲状腺ホルモンによるエネルギー消費を制御する)2011
- Author(s)
  白石千夏、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] 視床下部におけるnecdinは甲状腺ホルモンによるエネルギー消費を抑制する2011
- Author(s)
  白石千夏、長谷川孝一、吉川和明
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Interplay between necdin and Bmi1 regulates proliferation of embryonic neural stem cells2011
- Author(s)
  Ryohei Minamide, Koichi Hasegawa, Kazushiro Fujiwara, Kazuaki Yoshikawa
- Organizer
  ISN-ESN 23th Biennial Meeting
- Place of Presentation
  Athens Greece
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin enhances Sirt1-dependent deacetylation of Foxo1 to control hypothalamic thermoregulation2010
- Author(s)
  長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin regulates neural stem cell proliferation during postnatal development2010
- Author(s)
  橋長秀典、長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin enhances Sirt1-dependent deacetylation of Fox01 to control hypothalamic thermoregulation2010
- Author(s)
  長谷川孝一、川原知浩、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin serves as Nse3 in mammalian Smc5/ 6 complex2010
- Author(s)
  吉田直史、長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin enhances Sirt1-dependent deacetylation of Foxol to control hypothalamic thermoregulation2010
- Author(s)
  長谷川孝一
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin-Sirt1 complex regulates hypothalamic Foxo 1 acetylation to control energy homeostasis2010
- Author(s)
  長谷川孝一
- Organizer
  第53回神経化学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin controls proliferation of white adipocyte progenitors2010
- Author(s)
  藤原一志郎、長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin regulates Fox01 acetylation via Sirt1 in mouse hypothalamus Society for Neuroscience2010
- Author(s)
  Hasegawa K, Yoshikawa K
- Organizer
  40th Annual Meeting
- Place of Presentation
  San Diego USA
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin serves as Nse3 in mammalian Smc5/6 complex2010
- Author(s)
  吉田直史、長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin-Sirt1 complex regulates hypothalamic Foxo1 acetylation to control energy homeostasis(Necdin-Sirt1複合体による視床下部Foxo1のアセチル化の制御)2010
- Author(s)
  長谷川孝一、吉川和明
- Organizer
  第53回日本神経化学会大会(Neuro2010)
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Neural stem cell proliferation is regulated through interaction between necdin and Bmi1 polycomb complex protein(神経幹細胞の増殖はnecdinとポリコーム複合体タンパク質Bmi1の相互作用によって制御されている)2010
- Author(s)
  南出良平、長谷川孝一、大雲剛志、吉川和明
- Organizer
  第53回日本神経化学会大会(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin-Sirt1 complex regulates hypothalamic Foxo1 acetylation to control energy homeostasis(Necdin-Sirt1 複合体による視床下部Foxo1のアセル化の制御)2010
- Author(s)
  長谷川孝一、吉川和明
- Organizer
  第53回日本神経化学会大会(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin regulates Foxo1acetylation via Sirt1 in mouse hypothalamus Neuroscience 20102010
- Author(s)
  長谷川孝一, 吉川和明
- Organizer
  40th Annual Meeting
- Place of Presentation
  San Diego CA
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Regulation of Foxo1 acetylation by neuronal necdin-Sirt1 complex2010
- Author(s)
  Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  The Joint Symposium of the 5th International Symposium of Institute Network
- Place of Presentation
  KKR Hotel Kanazawa(石川県)
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin regulates Foxo1 acetylation via Sirt1 in mouse hypothalamus2010
- Author(s)
  長谷川孝一
- Organizer
  Neuroscience 2010 40th Annual Meeting
- Place of Presentation
  米国・サンディエゴコンベンションセンター
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Regulation of Foxo1 acetylation by neuronal necdin-Sirt1 complex2010
- Author(s)
  長谷川孝一, 吉川和明
- Organizer
  The Joint Symposium of the 5th International Symposium of Institute Network
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin enhances Sirt1-dependent deacetylation of Foxo1 to control hypothalamic thermoregulation2010
- Author(s)
  長谷川孝一、吉川和明
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Epigenetic regulation of necdin gene expression during neural development(神経分化におけるnecdin遺伝子のエピジェティックな発現制御)2010
- Author(s)
  大雲剛志、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第53回日本神経化学会大会(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin regulates Foxo1 acetylation via Sirt1 in mouse hypothalamus2010
- Author(s)
  Koichi Hasegawa, Kazuaki Yoshikawa
- Organizer
  Neuroscience 2010 40^<th> Annual Meeting
- Place of Presentation
  San Diego Convention Center (USA)
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] The necdin-Sirtl complex deacetylates Foxol to suppress its trancriptional activity2009
- Author(s)
  長谷川孝一
- Organizer
  第82回生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21300138
[Presentation] Necdin regulates adipocyte differentiation via mitotic clonal expansion(Necdinによる脂肪細胞分化の制御機構の解析)2009
- Author(s)
  藤原一志郎、長谷川孝一、大雲剛志、吉川和明
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Regulated expression of MAGE family genes during neural development2009
- Author(s)
  大雲剛志、蔡宗樺、長谷川孝一、吉川和明
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Acetylation status of transcription factors is regulated by neuronal necdin-Sirt1 complex(ニューロンにおけるnecdin-Sirt1複合体による転写因子アセチル化状態の制御)2009
- Author(s)
  長谷川孝一
- Organizer
  Institute for Protein Research Retreat
- Place of Presentation
  Hyogo
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Regulation of necdin expression by DNAmethylation during neural development(神経発生におけるnecdin遺伝子のメチル化による発現調節)2009
- Author(s)
  大雲剛志、蔡宗樺、長谷川孝一、吉川和明
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin-Sirt1複合体はFoxo1を脱アセチル化して転写活性を抑制する2009
- Author(s)
  長谷川孝一、川原知浩、吉川和明
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] The necdin-Sirt1complex deacetylates Foxo1 to suppress its transcriptional activity (Necdin-Sirt1複合体はFoxo1を脱アセチル化して転写活性を抑制する)2009
- Author(s)
  長谷川孝一、吉川和明
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890123
[Presentation] Necdin天然変性領域の機能解析
- Author(s)
  藤本泉、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] Necdinによるニューロン内ミトコンドリア機能の促進：パーキンソン病モデルにおける神経保護作用
- Author(s)
  長谷川孝一、安田徹、白石千夏、藤原一志郎、望月秀樹、吉川和明
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館 (奈良市)
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] NecdinとBmi1の拮抗的相互作用による神経幹細胞の増殖制御
- Author(s)
  南出良平、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第56回日本神経化学会大会 (Neuro2013)
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] NecdinによるRanGAP1のSUMO化制御
- Author(s)
  藤原一志郎、長谷川孝一、吉川和明
- Organizer
  第８6回日本生化学会大会
- Place of Presentation
  パシフィコ横浜 (横浜市）
- Year and Date
  2013-09-11 – 2013-09-13
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] 視床下部Necdinによるエネルギー代謝関連因子の調節
- Author(s)
  長谷川孝一
- Organizer
  蛋白質研究所セミナー
- Place of Presentation
  蛋白質研究所（大阪府）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] 神経発生における哺乳類Smc5/6複合体要素の発現と安定化
- Author(s)
  片山雄太、藤原一志郎、長谷川孝一、吉川和明
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] 哺乳類ニューロンのDNA修復におけるNecdinの関与
- Author(s)
  瀬戸口良、長谷川孝一、三澤昭博、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] NecdinとBmi1の拮抗的相互作用による神経幹細胞の増殖制御
- Author(s)
  南出良平、長谷川孝一、藤原一志郎　吉川和明
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  国立京都国際会館 (京都市）
- Year and Date
  2013-06-20 – 2013-06-23
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] NecdinによるPGC-1alphaを介したニューロン内ミトコンドリア生合成の促進
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] NecdinによるPGC-1αの安定化を介したニューロン内ミトコンドリア生合成の促進
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  国立京都国際会館 (京都市）
- Year and Date
  2013-06-20 – 2013-06-23
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdinは脳室下帯における神経前駆細胞の増殖を制御する
- Author(s)
  橋長秀典、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第56回日本神経化学会大会 (Neuro2013)
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] NecdinによるPGC-1αの安定化を介したニューロン内ミトコンドリア生合成の促進
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第56回日本神経化学会大会 (Neuro2013)
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア機能の促進
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎、吉川和明
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25830053
[Presentation] In vitro SUMO化反応系によるNecdinのSUMO修飾解析
- Author(s)
  藤原一志郎、長谷川孝一、江連徹、吉川和明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-23700445
[Presentation] Necdin suppresses PIAS1 SUMO E3 ligase activity by promoting ubiquitin-dependent degradation
- Author(s)
  GUR Ibrahim、藤原一志郎、長谷川孝一、吉川和明
- Organizer
  第８6回日本生化学会大会
- Place of Presentation
  パシフィコ横浜 (横浜市）
- Year and Date
  2013-09-11 – 2013-09-13
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdin regulates RanGAP1 sumoylation during neuronal differentiation
- Author(s)
  Fujiwara, K., Hasegawa, K., Yoshikawa, K.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Walter E. Washington Convention Center, Washington D.C.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア機能の促進
- Author(s)
  長谷川孝一、白石千夏、藤原一志郎　吉川和明
- Organizer
  第８6回日本生化学会大会
- Place of Presentation
  パシフィコ横浜 (横浜市）
- Year and Date
  2013-09-11 – 2013-09-13
- Data Source
  KAKENHI-PROJECT-24300134
[Presentation] Necdinによる上皮成長因子受容体シグナルの制御機構
- Author(s)
  藤本泉、長谷川孝一、藤原一志郎、吉川和明
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館 (京都市)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24300134

1. YOSHIKAWA Kazuaki (30094452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 32 results
2. OHKUMO Tsuyoshi (50432505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. FUJIWARA Kazushiro (80638495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
4. NAKAMURA Haruki (80134485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MOCHIZUKI Hideki (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. KUWAKO Ken-ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 山田雅司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hasegawa Koichi 長谷川 孝一

長谷川 孝一 ハセガワ コウイチ

HASEGAWA Koichi 長谷川 孝一

Research Projects

Research Products

Co-Researchers

Elucidation of the control system of axon initial segment starting from the nucleusPrincipal Investigator

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Regulation of mitochondrial biogenesis and function by necdin-Sirt1 complexPrincipal Investigator

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Strengthening mechanism of neuronal vitality by necdin

Principal Investigator

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Regulation of energy metabolism by necdin-Sirt1 complexPrincipal Investigator

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Mechanisms maintaining neuronal survival via necdin-centered protein interaction networks

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Regulation of transcription factors and neuronal development by necdin-Sirt1 complexPrincipal Investigator

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[Journal Article] Molecular mechanisms regulating the spatial configuration of neurites.2022

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[Journal Article] Vascularization of human brain organoids.2021

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[Journal Article] Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells2016

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[Journal Article] Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults2016

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[Journal Article] Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells2016

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[Journal Article] Necdin Promotes Ubiquitin-Dependent Degradation of PIAS1 SUMO E3 ligase2014

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[Journal Article] Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex.2014

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[Journal Article] Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.2013

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Hasegawa Koichi 長谷川孝一

長谷川孝一ハセガワコウイチ

HASEGAWA Koichi 長谷川孝一