KIMATA Masaki 木股正樹

… Alternative Names

木股正樹キマタマサキ

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Researcher Number	20548440
Affiliation (Current)	2026: 京都府立医科大学, 大学院医学研究科, 助教
Affiliation (based on the past Project Information) *help	2009 – 2010: Kyoto Prefectural University of Medicine, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator TOGAR / TIGAR / エネルギー代謝 / p53 / 心不全 / ミトコンドリア / p53,心不全

Research Projects
(1 results)
Research Products
(32 results)

Research for heart failure by regulating myocardial energy metabolism with p53 and TIGAR.Principal Investigator
- Principal Investigator
  
  KIMATA Masaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto Prefectural University of Medicine

All 2012 2010 2009

All Journal Article Presentation

[Journal Article] p53 promotes cardiac dysfunction in diabetic mellitus due to excessive mitochondrial respiration-mediated ROS generation and lipid accumulation2012
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Okigaki M, Tanaka H, Takamatsu T, Matsubara H
- Journal Title
  
  Circ Heart Fail
  
  Volume: 5 Pages: 106-115
- Data Source
  KAKENHI-PROJECT-21890224
[Journal Article] p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia2012
- Author(s)
  Hoshino A, Matoba S, Iwai-Kanai E, Nakamura H, Kimata M, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Ueyama T, Okigaki M, Matsubara H
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 52 Pages: 175-184
- Data Source
  KAKENHI-PROJECT-21890224
[Journal Article] 53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.2010
- Author(s)
  Kimata M, Matoba S, et.al
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890224
[Journal Article] p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress2010
- Author(s)
  Kimata M, Matoba S, Iwai-Kanai E, Nakamura H, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Mita Y, Okigaki M, Ikeda K, Tatsumi T, Matsubara H
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 299
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53/TIGAR System Inhibits Glucose Metabolism and Augments Myocyte Apoptosis in Ischemic heart2010
- Author(s)
  Kimata M, Matoba S, Iwai-Kanai E, Nakamura H, Hoshino A, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 糖尿病性心筋障害において、p53の活性化は脂肪毒性を亢進する2010
- Author(s)
  中村英夫、的場聖明、金井恵理、木股正樹、星野温、中岡幹彦、片村真紀、大川善文、三田雄一郎松原弘明
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] Differential Roles of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways on Autophagy During Alphal-Adrenergic Agonist-Mediated Cardioprotection2010
- Author(s)
  木股正樹, 他
- Organizer
  日本循環器学会
- Place of Presentation
  京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 accelerates cardiac damage in diabetes.2010
- Author(s)
  中村英夫, 木股正樹, 他
- Organizer
  International Society of Heart Research
- Place of Presentation
  京都
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 promotes heart failure in diabetic mice.2010
- Author(s)
  中村英夫, 木股正樹, 他
- Organizer
  The 11th US-Japan-Asia Dialogue
- Place of Presentation
  東京
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53-mediated decrease in ROS signal reduces mitophagy via inactivation of Bnip3 to aggravate cardiac damage after ischemic injury.2010
- Author(s)
  星野温、木股正樹, 他
- Organizer
  ロアメリカ心臓学会
- Place of Presentation
  米国イリノイ州
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53-mediated acceleration of mitochondrial oxygen consumption promotes lipotoxicity via SCO2 in diabetic mice2010
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Mita Y, Tatsumi T, Matsubara H
- Organizer
  American Heart Association(米国心臓病学術会議)
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 modulates autophagy through mitochondrial redox signal regulation during myocardial ischemia.2010
- Author(s)
  木股正樹, 他
- Organizer
  日本循環器学会
- Place of Presentation
  京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] α1交感神経経路による心筋修復のメカニズム2010
- Author(s)
  大川善文、木股正樹, 他
- Organizer
  第19回日本cell death学会
- Place of Presentation
  名古屋
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53-mediated decrease in ROS signal reduces mitophagy via inactivation of Bnip3 to aggravate cardiac damage after ischemic injury2010
- Author(s)
  Hoshino A, Matoba S, Iwai-Kanai E, Kimata M, Nakamura H, Nakaoka M, Katamura M, Okawa Y, Mita Y, Tatsumi T, Matsubara H
- Organizer
  American Heart Association(米国心臓病学術会議)
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 promotes heart failure in diabetic cardiomyopathy2010
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 promotes heart failure in diabetic cardiomyopathy2010
- Author(s)
  木股正樹, 他
- Organizer
  日本循環器学会
- Place of Presentation
  京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 心筋虚血においてp53はミトファジーを抑制し心筋障害を増大する2010
- Author(s)
  星野温、木股正樹, 他
- Organizer
  第19回日本cell death学会
- Place of Presentation
  名古屋
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53-mediated acceleration of mitochondrial oxygen consumption promotes lipotoxicity via SCO2 in diabetic mice.2010
- Author(s)
  中村英夫、木股正樹, 他
- Organizer
  アメリカ心臓学会
- Place of Presentation
  米国イリノイ州
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 accelerates cardiac damage in diabetes2010
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Matsubara H
- Organizer
  International Society of Heart Research
- Place of Presentation
  Kyoto
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 promotes heart failure in diabetic mice2010
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Matsubara H
- Organizer
  The 11th US-Japan-Asia Dialogue
- Place of Presentation
  Tokyo
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 inhibits autophagy and accelerates apoptotic cell death through mitochondrial redox signal in ischemic myocardium2010
- Author(s)
  Hoshino A, Matoba S, Iwai-Kanai E, Kimata M, Nakamura H, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 心筋虚血においてp53はミトファジーを抑制し心筋障害を増大する2010
- Author(s)
  星野温、的場聖明、金井恵理、中岡幹彦、木股正樹、中村英夫、片村真紀、大川義文、三田雄一郎、松原弘明
- Organizer
  第19回日本cell death学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 糖尿病性心筋障害において、p53の活性化は脂肪毒性を亢進する2010
- Author(s)
  中村英夫、木股正樹, 他
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 交感神経刺激による心筋アポトーシス、オートファジーの制御2009
- Author(s)
  中岡幹彦、金井恵理、的場聖明、木股正樹、中村英夫、星野温、片村真紀、松原弘明
- Organizer
  第18回日本cell death学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] Differential Roles of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways on Autophagy During Alphal-Adrenergic Agonist-Mediated Cardioprotection2009
- Author(s)
  木股正樹, 他
- Organizer
  アメリカ心臓学会
- Place of Presentation
  米国フロリダ州
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] Differential Roles of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways on Autophagy During Alpha1-Adrenergic Agonist-Mediated Cardioprotection2009
- Author(s)
  Nakaoka M, Iwai-Kanai E, Matoba S, Kimata M, Nakamura H, Hoshino A, Katamura M, Hiraumi Y, Matsubara H
- Organizer
  American Heart Association(米国心臓病学術会議)
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] 交感神経の亢進による心筋オートファジーの誘導2009
- Author(s)
  中岡幹彦、金井恵理、的場聖明、木股正樹、中村英夫、星野温、片村真紀、松原弘明
- Organizer
  第32回日本高血圧学会総会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53発現抑制におけるオートファジーを介した虚血心筋保護効果2009
- Author(s)
  星野温、的場聖明、金井恵理、中岡幹彦、木股正樹、中村英夫、片村真紀、松原弘明
- Organizer
  第18回日本cell death学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] Hypoxia-Induced p53 Deteriorates Cardiac Energetics and Apoptotic Cell Death via TIGAR(TP53-Induced Glycolysis and Apoptosis Regulator)2009
- Author(s)
  Kimata M, Matoba S, Iwai-Kanai E, Nakamura H, Hoshino A, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 and SCO2(Synthesis of Cytochrome c Oxidase 2) Augment the Progression of Diabetic Cardiomyopathy2009
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53 Promotes Heart Failure With Lipid Accumulation in Diabetes2009
- Author(s)
  Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Tatsumi T, Matsubara H
- Organizer
  American Heart Association(米国心臓病学術会議)
- Place of Presentation
  Orlando, USA
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21890224
[Presentation] p53による解糖系調節とアポトーシス制御2009
- Author(s)
  木股正樹、的場聖明、金井恵理、中村英夫、星野温、中岡幹彦、平海良美、片村真紀、辰巳哲也、松原弘明
- Organizer
  第32回日本高血圧学会総会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-21890224

KIMATA Masaki 木股 正樹

木股 正樹 キマタ マサキ

Research Projects

Research Products

Research for heart failure by regulating myocardial energy metabolism with p53 and TIGAR.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] p53 promotes cardiac dysfunction in diabetic mellitus due to excessive mitochondrial respiration-mediated ROS generation and lipid accumulation2012

Author(s)

Journal Title

Data Source

[Journal Article] p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia2012

Author(s)

Journal Title

Data Source

[Journal Article] 53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.2010

Author(s)

Journal Title

Data Source

[Journal Article] p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress2010

Author(s)

Journal Title

Data Source

[Presentation] p53/TIGAR System Inhibits Glucose Metabolism and Augments Myocyte Apoptosis in Ischemic heart2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 糖尿病性心筋障害において、p53の活性化は脂肪毒性を亢進する2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Differential Roles of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways on Autophagy During Alphal-Adrenergic Agonist-Mediated Cardioprotection2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53 accelerates cardiac damage in diabetes.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53 promotes heart failure in diabetic mice.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53-mediated decrease in ROS signal reduces mitophagy via inactivation of Bnip3 to aggravate cardiac damage after ischemic injury.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53-mediated acceleration of mitochondrial oxygen consumption promotes lipotoxicity via SCO2 in diabetic mice2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] p53 modulates autophagy through mitochondrial redox signal regulation during myocardial ischemia.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] α1交感神経経路による心筋修復のメカニズム2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53-mediated decrease in ROS signal reduces mitophagy via inactivation of Bnip3 to aggravate cardiac damage after ischemic injury2010

Author(s)

Organizer

KIMATA Masaki 木股正樹

木股正樹キマタマサキ