MOHRI Dai 毛利大

Researcher Number	20582513
Affiliation (based on the past Project Information) *help	2014 – 2017: 東京大学, 医学部附属病院, 助教 2013: 東京大学, 医学部附属病院, その他 2013: 東京大学, 医学部附属病院, 特任臨床医 2013: 東京大学, 医学部附属病院, 特認臨床医 2012: 埼玉医科大学, 医学部, 助教 2011: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 分子標的薬 / 膵発癌マウスモデル Except Principal Investigator IPMN / 膵がん / 膵癌 / ｍTOR阻害剤 / ＭＡＰＫシグナル / mTOR阻害剤 / MEK阻害剤 / PI3Kシグナル / MAPKシグナル / 胆嚢癌

Study of IPMN-related carcinogenesis
- Principal Investigator
  
  Tada Minoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Molecular targeting therapy against intracellular signaling network in gallbladder cancer
- Principal Investigator
  
  SASAKI Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Molecular characterization of IPMN using comprehensive genome analysis
- Principal Investigator
  
  TADA Minoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Dual inhibition of MAPK and mTOR signaling on Pancreatic CancerPrincipal Investigator
- Principal Investigator
  
  MOHRI DAI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
  Saitama Medical University

All 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Other

[Journal Article] IPMN and pancreatic cyst as high risk of pancreatic cancer2015
- Author(s)
  Tada M, Takagi K, Kawakubo K,Takahara N, Takahashi R, Yamamoto K, Hamada T, Mizuno S, Miyabayashi K, Mohri D, Matsubara S, Kogure H, Nakai Y, Yamamoto N, Sasaki T, Sasahira N, Hirano K, Ijichi H, Tateishi K, Isayama H, Koike K et.al.
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 112 Issue: 8 Pages: 1474-1478
- DOI
  10.11405/nisshoshi.112.1474
- NAID
  130005091881
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09041
[Journal Article] Disease-Specific Mortality Among Patients With Intraductal Papillary Mucinous Neoplasm of the Pancreas2014
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Takahara N, Uchino R, Hamada T, Miyabayashi K, Yamamoto K, Mizuno S, Mohri D, Kogure H, Sasaki T, Yamamoto N, Hirano K, Ijichi H, Tateishi K, Koike K
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 12(3) (2013 Jul 25) Issue: 3 Pages: 486-91
- DOI
  10.1016/j.cgh.2013.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591009, KAKENHI-PROJECT-23591010, KAKENHI-PROJECT-25860514
[Journal Article] Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas2013
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Takahara N, Miyabayashi K, Yamamoto K, Mizuno S, Mohri D, Kogure H, Sasaki T, Yamamoto N, Tateishi R, Hirano K, Ijichi H, Tateishi K, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 42(4) Pages: 687-91
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] One-step, simultaneous triple endoscopic nasobiliary drainage for hilar biliary stricture2013
- Author(s)
  Kawakubo K, Isayama H, Mizuno S, Hirano K, Yamamoto N, Takahara N, Miyabayashi K, Mohri D, Sasaki T, Kogure H, Sasahira N, Tada M, Koike K
- Journal Title
  
  Dig Endosc
  
  Volume: 25(1) Pages: 76-9
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Risk factors and early signs of pancreatic cancer in diabetes : screening strategy based on diabetes onset age2013
- Author(s)
  Mizuno S, Nakai Y, Isayama H, Yanai A, Takahara N, Miyabayashi K, Yamamoto K, Kawakubo K, Mohri D, Kogure H, Sasaki T, Yamamoto N, Sasahira N, Hirano K, Tsujino T, Ijichi H, Tateishi K, Akanuma M, Tada M, Koike K
- Journal Title
  
  J Gastroenterol
  
  Volume: 48(2) Pages: 238-46
- NAID
  10031156309
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer2013
- Author(s)
  Takahara N, Nakai Y, Isayama H, Sasaki T, Satoh Y, Takai D, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Mohri D, Kawakubo K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tada M, Yatomi Y, Koike K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71(1) Pages: 85-92
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Diabetes is a useful diagnostic clue to improve the prognosis of pancreatic cancer2013
- Author(s)
  Mizuno S, Nakai Y, Isayama H, Takahara N, Miyabayashi K, Yamamoto K, Kawakubo K, Mohri D, Kogure H, Sasaki T, Yamamoto N, Sasahira N, Hirano K, Tsujino T, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Pancreatology
  
  Volume: 13(3) Pages: 285-9
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals2013
- Author(s)
  Miyabayashi K, Ijichi H, Mohri D, Tada M, Yamamoto K, Asaoka Y, Ikenoue T, Tateishi K, Nakai Y, Isayama H, Morishita Y, Omata M, Moses HL, Koike K
- Journal Title
  
  Cancer Res
  
  Volume: 73(7) Pages: 2221-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790773
[Journal Article] High alcohol consumption increases the risk of pancreatic stone formation and pancreatic atrophy in autoimmune pancreatitis2013
- Author(s)
  Hirano K, Tada M, Isayama H, Watanabe T, Saito T, Uchino R, Hamada T, Miyabayashi K, Mizuno S, Mohri D, Sasaki T, Kogure H, Yamamoto N, Sasahira N, Toda N, Takahara N, Yagioka H, Akiyama D, Ito Y, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 42(3) Pages: 502-5
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas2013
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Takahara N, Miyabayashi K, Yamamoto K, Mizuno S, Mohri D, Kogure H, Sasaki T, Yamamoto N, Tateishi R, Hirano K, Ijichi H, Tateishi K, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 42(4) Issue: 4 Pages: 687-91
- DOI
  10.1097/mpa.0b013e318270ea97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591009, KAKENHI-PROJECT-23591010
[Journal Article] Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial2013
- Author(s)
  Uchino R, Isayama H, Tsujino T, Sasahira N, Ito Y, Matsubara S, Takahara N, Arizumi T, Toda N, Mohri D, Togawa O, Yagioka H, Yanagihara Y, Nakajima K, Akiyama D, Hamada T, Miyabayashi K, Mizuno S, Kawakubo K, Kogure H, Sasaki T, Yamamoto N, Nakai Y, Hirano K, Tada M, Koike K
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 78(6) Pages: 842-50
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] A retrospective analysis of early CA19-9 change in salvage chemotherapy for refractory pancreatic cancer2013
- Author(s)
  Nakai Y, Isayama H, Sasaki T, Takahara N, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Yamamoto K, Mohri D, Kogure H, Yamamoto N, Hirano K, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 72(6) Pages: 1291-7
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Endoscopic removal of a spontaneously fractured biliary uncovered self-expandable metal stent2012
- Author(s)
  Kawakubo K, Isayama H, Tsujino T, Nakai Y, Sasahira N, Kogure H, Hamada T, Nagano R, Miyabayashi K, Yamamoto K, Mohri D, Sasaki T, Ito Y, Yamamoto N, Hirano K, Tada M, Koike K
- Journal Title
  
  Dig Endosc
  
  Volume: 24(3) Pages: 182-4
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression.2012
- Author(s)
  Mohri D, Asaoka Y, Ijichi H, Miyabayashi K, Kudo Y, Seto M, Ohta M, Tada M, Tanaka Y, Ikenoue T, Tateishi K, Isayama H, Kanai F, Fukushima N, Tada M, Kawabe T, Omata M, Koike K.
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 203-13
- NAID
  10030296319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression2012
- Author(s)
  Mohri D, Asaoka Y, Ijichi H, Miyabayashi K, Kudo Y, Seto M, Ohta M, Tada M, Tanaka Y, Ikenoue T, Tateishi K, Isayama H, Kanai F, Fukushima N, Tada M, Kawabe T, Omata M, Koike K
- Journal Title
  
  J Gastroenterol
  
  Volume: 47(2) Pages: 203-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790773
[Journal Article] Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression2012
- Author(s)
  Mohri D, Asaoka Y, Ijichi H, Miyabayashi K, Kudo Y, Seto M, Ohta M, Tada M, Tanaka Y, Ikenoue T, Tateishi K, Isayama H, Kanai F, Fukushima N, Tada M, Kawabe T, Omata M, Koike K
- Journal Title
  
  J Gastroenterol
  
  Volume: 47(2) Pages: 203-13
- NAID
  10030296319
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Clinical utility of single-operator cholangiopancreatoscopy using a SpyGlass probe through an endoscopic retrograde cholangiopancreatography catheter2012
- Author(s)
  Kawakubo K, Isayama H, Sasahira N, Kogure H, Takahara N, Miyabayashi K, Mizuno S, Yamamoto K, Mohri D, Sasaki T, Yamamoto N, Nakai Y, Hirano K, Tada M, Koike K
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 27(8) Pages: 1371-6
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E2012
- Author(s)
  Hirano K, Tada M, Mizuno S, Isayama H, Takahara N, Nagano R, Hamada T, Miyabayashi K, Ito Y, Mohri D, Kawakubo K, Sasaki T, Kogure H, Yamamoto N, Sasahira N, Yamashiki N, Sugawara Y, Kokudo N, Toda N, Koike K
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 10(1) Pages: 79-83
- NAID
  40019405097
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Long-term prognosis of autoimmune pancreatitis in terms of glucose tolerance2012
- Author(s)
  Hirano K, Isogawa A, Tada M, Isayama H, Takahara N, Miyabayashi K, Mizuno S, Mohri D, Kawakubo K, Sasaki T, Kogure H, Yamamoto N, Sasahira N, Toda N, Nagano R, Yagioka H, Yashima Y, Hamada T, Ito Y, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 41(5) Pages: 691-5
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Phase I trial of gemcitabine and candesartan combination therapy in normotensive patients with advanced pancreatic cancer : GECA12012
- Author(s)
  Nakai Y, Isayama H, Ijichi H, Sasaki T, Kogure H, Yagioka H, Miyabayashi K, Mizuno S, Yamamoto K, Mouri D, Kawakubo K, Yamamoto N, Hirano K, Sasahira N, Tateishi K, Tada M, Koike K
- Journal Title
  
  Cancer Sci
  
  Volume: 103(8) Pages: 1489-92
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Recent progress and limitations of chemotherapy for pancreatic and biliary tract cancers2011
- Author(s)
  Tada M , Nakai Y, Sasaki T, Hamada T, Nagano R, Mohri D, Miyabayashi K, Yamamoto K, Kogure H, Kawakubo K, Ito Y, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tateishi K, Isayama H, Omata M, Koike K
- Journal Title
  
  World J Clin Oncol
  
  Volume: 2(3) Pages: 158-63
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Clinical significance of bile cytology via an endoscopic nasobiliary drainage tube for pathological diagnosis of malignant biliary strictures2011
- Author(s)
  Yagioka H, Hirano K, Isayama H, Tsujino T, Sasahira N, Nagano R, Hamada T, Miyabayashi K, Ito Y, Mohri D, Kawakubo K, Kogure H, Sasaki T, Tada M, Koike K
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 18(2) Pages: 211-5
- NAID
  10029286323
- Data Source
  KAKENHI-PROJECT-23591010
[Journal Article] Duodenal invasion is a risk factor for the early dysfunction of biliary metal stents in unresectable pancreatic cancer2011
- Author(s)
  Hamada T, Isayama H, Nakai Y, Togawa O, Kogure H, Kawakubo K, Tsujino T, Sasahira N, Hirano K, Yamamoto N, Arizumi T, Ito Y, Matsubara S, Sasaki T, Yagioka H, Yashima Y, Mohri D, Miyabayashi K, Mizuno S, Nagano R, Takahara N, Toda N, Tada M, Omata M, Koike K
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 74(3) Pages: 548-55
- Data Source
  KAKENHI-PROJECT-23591010
[Presentation] IPMNにおける膵発癌危険因子の検討2012
- Author(s)
  川久保和道,多田稔,伊佐山浩通,笹平直樹,平野賢二,高原楠昊,宮林弘至,水野卓,毛利大,佐々木隆,木暮宏史,山本夏代,小池和彦
- Organizer
  第43回日本膵臓学会シンポジウム
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23591010
[Presentation] 胆嚢癌に対するmTORとMAPKを標的とした治療法の検討2011
- Author(s)
  毛利大、伊地知秀明、小池和彦
- Organizer
  第53回日本消化器病学会大会・パネルディスカッション
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790773
[Presentation] 胆嚢癌化学療法における内臓脂肪の臨床的意義
- Author(s)
  毛利大
- Organizer
  第22回日本消化器関連学会週間
- Place of Presentation
  神戸
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-24591008
[]

1. TADA Minoru (80302719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. TATEISHI Keisuke (20396948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. SASAKI Takashi (10569106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. IJICHI Hideaki (70463841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IKENOUE Tsuneo (80396712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 松原三郎 (40750550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 木暮宏史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 山本夏代

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MOHRI Dai 毛利 大

Research Projects

Research Products

Co-Researchers

Study of IPMN-related carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular targeting therapy against intracellular signaling network in gallbladder cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular characterization of IPMN using comprehensive genome analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dual inhibition of MAPK and mTOR signaling on Pancreatic CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IPMN and pancreatic cyst as high risk of pancreatic cancer2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Disease-Specific Mortality Among Patients With Intraductal Papillary Mucinous Neoplasm of the Pancreas2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas2013

Author(s)

Journal Title

Data Source

[Journal Article] One-step, simultaneous triple endoscopic nasobiliary drainage for hilar biliary stricture2013

Author(s)

Journal Title

Data Source

[Journal Article] Risk factors and early signs of pancreatic cancer in diabetes : screening strategy based on diabetes onset age2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] Diabetes is a useful diagnostic clue to improve the prognosis of pancreatic cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals2013

Author(s)

Journal Title

Data Source

[Journal Article] High alcohol consumption increases the risk of pancreatic stone formation and pancreatic atrophy in autoimmune pancreatitis2013

Author(s)

Journal Title

Data Source

[Journal Article] Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial2013

Author(s)

Journal Title

Data Source

[Journal Article] A retrospective analysis of early CA19-9 change in salvage chemotherapy for refractory pancreatic cancer2013

MOHRI Dai 毛利大