Yamano Noriko 山野範子

Researcher Number	20582795
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院工学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院工学研究科, 准教授 2018 – 2021: 大阪大学, 工学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / 0401:Materials engineering, chemical engineering, and related fields Except Principal Investigator Medium-sized Section 27:Chemical engineering and related fields
Keywords	Principal Investigator ゲノム / 新規宿主細胞 / バイオ医薬品 / 動物細胞 / 安定染色体 / 抗体生産 / トランスクリプトーム / 染色体異数性 / 染色体不分離 / 染色体不安定性 / 宿主細胞 / CHO細胞 / 組換えタンパク質生産 … More Except Principal Investigator … More VLP / 細胞培養プロセス / 抗体 / バイオ医薬品 / セルエンジニアリング / 細胞内トラフィック / 工業用動物細胞 Less

Construction of mammalian cell-based cell and bioprocess engineering
- Principal Investigator
  
  大政健史
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Osaka University
Whole genome analysis and construction of a karyotype image analysis system for novel biopharmaceutical production host cellsPrincipal Investigator
- Principal Investigator
  
  Yamano Noriko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Osaka University
Utilization of chromosomal instability in CHO cells in recombinant protein productionPrincipal Investigator
- Principal Investigator
  
  Yamano Noriko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0401:Materials engineering, chemical engineering, and related fields
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Construction of a novel kinetic model for the production process of a CVA6 VLP vaccine in CHO cells2024
- Author(s)
  Zhou Xing, Thao Bich Nguyen, Guirong Kanai-Bai, Noriko Yamano-Adachi and Takeshi Omasa
- Journal Title
  
  Cytotechnology
  
  Volume: 76 Issue: 1 Pages: 69-83
- DOI
  10.1007/s10616-023-00598-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00276
[Journal Article] Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones2024
- Author(s)
  Yamano-Adachi Noriko、Hata Hirofumi、Nakanishi Yuto、Omasa Takeshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 137 Issue: 1 Pages: 54-63
- DOI
  10.1016/j.jbiosc.2023.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K04788, KAKENHI-PROJECT-22H00276
[Journal Article] 次世代型抗体生産のためのホスト細胞開発2023
- Author(s)
  山野-足立範子
- Journal Title
  
  Seibutsu-kogaku Kaishi
  
  Volume: 101 Issue: 6 Pages: 285-288
- DOI
  10.34565/seibutsukogaku.101.6_285
- ISSN
  0919-3758, 2435-8630
- Year and Date
  2023-06-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K04788
[Journal Article] Synthesis of Human Antibodies Against HBsAg in Newly Established Chinese Hamster Lung (CHL-YN) Cell Line2023
- Author(s)
  Hakim Meutia Diva、Yamano- Adachi Noriko、Omasa Takeshi、Tan Marselina Irasonia、Juliawaty Lia Dewi、Giri-Rachman Ernawati Arifin
- Journal Title
  
  Journal of Mathematical and Fundamental Sciences
  
  Volume: 54 Issue: 3 Pages: 290-301
- DOI
  10.5614/j.math.fund.sci.2023.54.3.1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Journal Article] Recent advances in animal cell technologies for industrial and medical applications2022
- Author(s)
  Horie Masanobu、Yamano-Adachi Noriko、Kawabe Yoshinori、Kaneoka Hidenori、Fujita Hideaki、Nagamori Eiji、Iwai Ryosuke、Sato Yasushi、Kanie Kei、Ohta Seiichi、Somiya Masaharu、Ino Kosuke
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: - Issue: 6 Pages: 509-514
- DOI
  10.1016/j.jbiosc.2022.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H01722, KAKENHI-PROJECT-20K22489, KAKENHI-PROJECT-21K04787, KAKENHI-PROJECT-21K04788, KAKENHI-PROJECT-20K05226, KAKENHI-PLANNED-21H05092
[Journal Article] Artificial induction of chromosome aneuploidy in CHO cells alters their function as host cells2022
- Author(s)
  Yamano‐Adachi Noriko、Nakanishi Yuto、Tanaka Wataru、Lai YuanShan、Yamazaki Masahiro、Zenner Laura、Hata Hirofumi、Omasa Takeshi
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 120 Issue: 3 Pages: 659-673
- DOI
  10.1002/bit.28289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04788, KAKENHI-PROJECT-22H00276
[Journal Article] 生物（細胞）にしかできないモノつくり2022
- Author(s)
  山野-足立範子
- Journal Title
  
  Seibutsu-kogaku Kaishi
  
  Volume: 100 Issue: 7 Pages: 381-381
- DOI
  10.34565/seibutsukogaku.100.7_381
- ISSN
  0919-3758, 2435-8630
- Year and Date
  2022-07-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K04788
[Journal Article] Effect of co-overexpression of the cargo receptor ERGIC-53/MCFD2 on antibody production and intracellular IgG secretion in recombinant Chinese hamster ovary cells2022
- Author(s)
  Kirimoto Yutaka、Yamano-Adachi Noriko、Koga Yuichi、Omasa Takeshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: - Issue: 5 Pages: 400-406
- DOI
  10.1016/j.jbiosc.2022.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00276
[Journal Article] 組換えタンパク質生産における染色体不安定性の利用2021
- Author(s)
  山野-足立範子
- Journal Title
  
  月刊 Precision Medicine　2021年7月臨時増刊号
  
  Volume: 4 Pages: 77-81
- Data Source
  KAKENHI-PROJECT-21K04788
[Journal Article] 組換えタンパク質を生産するための優れた宿主細胞とは2021
- Author(s)
  山野-足立範子
- Journal Title
  
  季刊誌生産と技術
  
  Volume: 73 Pages: 68-71
- Data Source
  KAKENHI-PROJECT-21K04788
[Journal Article] 組換えタンパク質生産における染色体不安定性の利用2020
- Author(s)
  山野-足立範子
- Journal Title
  
  月刊「細胞」2020年7月号　特集　染色体医工学
  
  Volume: 52 Pages: 39-42
- Data Source
  KAKENHI-PROJECT-19K21105
[Journal Article] The effect of telomere sequences on chromosomal translocations2020
- Author(s)
  Jun Ho Lee, Wataru Tanaka, Noriko Yamano-Adachi, Yuichi Koga, Takeshi Omasa
- Journal Title
  
  BMC Proceedings 2020
  
  Volume: 14(Suppl 5) Issue: S5 Pages: 16-17
- DOI
  10.1186/s12919-020-00188-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21105, KAKENHI-PROJECT-19H02525
[Journal Article] Characterization of Chinese hamster ovary cells with disparate chromosome numbers: Reduction of the amount of mRNA relative to total protein2020
- Author(s)
  NorikoYamano-Adachi, Norichika Ogata, Sho Tanaka, Masayoshi Onitsuka, Takeshi Omasa
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 129 Issue: 1 Pages: 121-128
- DOI
  10.1016/j.jbiosc.2019.06.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21105, KAKENHI-PROJECT-17H06157
[Presentation] 抗体生産宿主として有用性が示されたCHO細胞株の高生産性を示す要因の解明2023
- Author(s)
  山﨑雅大，中西悠人，山野-足立範子，大政健史
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] CHL-YN cells from Osaka University to the world2023
- Author(s)
  Noriko Yamano-Adachi
- Organizer
  International Symposium in Biotechnology (ISBIO)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Effect of host genome completeness on virus detection by next generation sequencing: Importance of a high-quality reference genome for viral safety2023
- Author(s)
  Tomoko Matsuda, Norichika Ogata, Aoi Hosaka, Noriko Yamano-Adachi, Noriko Hashiba, Keisuke Yusa, Kazuhisa Uchida, Yoshinori Kawabe, Masamichi Kamihira, Sei Murakami, and Takeshi Omasa
- Organizer
  The 28th Young Asian Biological Engineers' Community (YABEC2023) (BEST-YABEC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] チャイニーズハムスター肺細胞からのiPS細胞の樹立と分化誘導の検討2023
- Author(s)
  藤岡晴生, 吉田貴美, 金井貴蓉, 山野-足立範子, 大政健史
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Development of a COVID-19 vaccine candidate based on the SpyTag/SpyCatcher system2023
- Author(s)
  Seoyeon Nam, Bich Thao Nguyen, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  36th Annual and international meeting of Japanese Association for Animal Cell Technology (JAACT '23)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] SARS-CoV-2ウイルス様粒子を生産するCHO-K1細胞株の構築2023
- Author(s)
  森下悠希,ナムソヨン, 保木本達也,山野-足立範子,大政健史
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Sar1A過剰発現CHO細胞におけるCOPII小胞の形成促進が小胞体局在タンパク質に与える影響2023
- Author(s)
  吉池知安留,角田悠,山野-足立範子,大政健史
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 重力沈降型小型灌流培養装置を用いたグルタミン不含培地におけるCHL-YN細胞培養2023
- Author(s)
  長江彩夏，國田紘夢，山野-足立範子，大政健史
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] グルタミンを含むジペプチドがCHL-YN細胞の代謝及び抗体生産に及ぼす影響2023
- Author(s)
  佐渡友大輝，スクワットタナニパットプリワット，山野-足立範子，大政健史
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] 倍速で増える日本発オリジナルCHL-YN細胞の樹立と展望2023
- Author(s)
  山野-足立範子
- Organizer
  バイオインダストリー協会 Cutting-edge Bio-seminar 3「日本発オリジナル技術が世界を変える！」
- Invited
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Construction of production system using CHO cells for chimeric HBsAg-VLPs presenting SARS-CoV-2 T-cell epitope2023
- Author(s)
  Yuki Morishita, Nam Seoyeon, Thao Bich Nguyen, Guirong Kanai, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  36th Annual and international meeting of Japanese Association for Animal Cell Technology (JAACT '23)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 抗体生産宿主として有用性が示されたCHO細胞株の高生産性を示す要因の解明2023
- Author(s)
  山﨑雅大, 中西悠人, 山野-足立範子, 大政健史
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] CHO cell line expressing enterovirus 71 VLPs in a fed-batch process: A new potential production platform2023
- Author(s)
  Thao Bich Nguyen, Guirong Kanai, Noriko Yamano-Adachi, Takeshi Omasa, and Susumu Ochiai
- Organizer
  20th Annual PepTalk 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] De novo genome assembly of the Chinese hamster-derived cell lines2023
- Author(s)
  Aoi Hosaka, Tomoko Matsuda, Norichika Ogata, Noriko Yamano-Adachi, Yoshinori Kawabe, Masamichi Kamihira, Sei Murakami, and Takeshi Omasa
- Organizer
  The 28th Young Asian Biological Engineers' Community (YABEC2023) (BEST-YABEC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Exploring the expression bottleneck of shark derived IgNAR antibodies produced in Chinese hamster ovary cells2023
- Author(s)
  Xiaofang Lyu, Masayoshi Onitsuka, Noriko Yamano-Adachi, Yuichi Koga, and Takeshi Omasa
- Organizer
  he 28th Young Asian Biological Engineers' Community (YABEC2023) (BEST-YABEC),
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Investigation of the expression difficulties of shark-derived immunoglobulin new antigen receptor in Chinese hamster ovary cells2023
- Author(s)
  Yunchi Zhang, Xiaofang Lyu, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  第75回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] A single cell transcriptome comparison between common CHO cell lines and a novel cell line derived from lung tissue of Chinese hamsters (CHL-YN cells)2023
- Author(s)
  Tomoko Matsuda, Norichika Ogata, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  The 16th Asian Congress on Biotechnology (ACB) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Investigation of intracellular secretory process in Sar1A-overexpressed CHO cells for further improvement of IgG productivity2023
- Author(s)
  Chiato Yoshiike, Yu Tsunoda, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  36th Annual and international meeting of Japanese Association for Animal Cell Technology (JAACT '23)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] SpyTag/SpyCatcherシステムを用いたSARS-CoV-2-VLP生産系構築2023
- Author(s)
  Nam Seoyeon, Nguyen Bich Thao, 山野-足立範子, 大政健史
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Overexpression of Sar1A in CHO cells and its effects on antibody production and intracellular antibody trafficking2023
- Author(s)
  Yu Tsunoda, Noriko Yamano-Adachi, and Takeshi Omasa
- Organizer
  The 28th Young Asian Biological Engineers' Community (YABEC2023) (BEST-YABEC),
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Modeling of virus-like particle (VLP) vaccine production process using Chinese hamster ovary (CHO) cell culture2022
- Author(s)
  Xing Zhou, Thao Bich Nguyen, Noriko Yamano-Adachi and Takeshi Omasa
- Organizer
  the 15th Asian Congress on Biotechnology 2022 (ACB2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] SpyTag/SpyCatcher システムを用いたSARS-CoV-2-VLP ワクチンの開発2022
- Author(s)
  NAM SEOYEON, 保木本達也, Nguyen Bich Thao, 金井貴蓉, 山野-足立範子,大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Generation of New Production Host Cells from Chinese Hamster Lung Tissue2022
- Author(s)
  Noriko Yamano-Adachi
- Organizer
  The 15th Asian Congress on Biotechnology in conjunction with The 7th International Symposium on Biomedical Engineering
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] 抗体生産宿主として有用性の示された高染色体数を持つCHO 細胞株の特徴解析とその高生産性を示す要因の解明2022
- Author(s)
  山﨑雅大, 中西悠人, 山野‐足立範子, 大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 新規生産宿主細胞CHL－YN 細胞を用いたグルタミンフリー培養におけるアンモニア濃度への影響2022
- Author(s)
  古藤隆衣, 山野-足立範子, 有島凛太郎, 古賀雄一, 大政健史
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Development of novel fast-growing Chinese hamster lung (CHL)-YN cells in serum-free fed-batch for monoclonal antibody production2022
- Author(s)
  Puriwat Sukwattananipaat, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  The 27th Meeting of the European Society for Animal Cell Technology (ESACT2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Overexpression of Sar1A in CHO cells and its effects on antibody production and localization of intracellular antibodies2022
- Author(s)
  Yu Tsunoda, Noriko Yamano-Adachi and Takeshi Omasa
- Organizer
  the 15th Asian Congress on Biotechnology 2022 (ACB2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] CHO 細胞におけるSar1A 過剰発現の抗体生産性および分泌プロセスへ与える影響2022
- Author(s)
  角田悠, 山野-足立範子, 大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Acceleration of process development of CVA6 VLP vaccine production in CHO cells with a novel kinetic model2022
- Author(s)
  Xing Zhou, Thao Bich Nguyen, Noriko Yamano-Adachi and Takeshi Omasa
- Organizer
  The 27th Young Asian Biological Engineers' Community (YABEC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 染色体異数性誘発により単離されたCHO細胞株の抗体生産宿主としての有用性とその特徴解析2022
- Author(s)
  山﨑雅大，中西悠人，田中航，畑展史，山野-足立範子，大政健史
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] チャイニーズハムスター肺細胞由来のiPS 細胞の樹立2022
- Author(s)
  藤岡晴生, 吉田貴美, 金井貴蓉, 山野-足立範子, 古賀雄一, 大政健史
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] バイオリアクターを用いたヒトiPS 細胞からのNK 細胞分化誘導の検討2022
- Author(s)
  畑岡尭也, 金井貴蓉, 山野-足立範子, 大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 抗体生産宿主として有用性の示された高染色体数を持つCHO 細胞株の特徴解析とその高生産性を示す要因の解明2022
- Author(s)
  山﨑雅大, 中西悠人, 山野-足立範子, 大政健史
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] CHL-YN 細胞の重力沈降型小型灌流培養2022
- Author(s)
  國田紘夢, Sukwattananipaat Puriwat, 古賀雄一, 山野-足立範子, 大政健史
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] LC-MS/MS を用いた培養上清/細胞内抽出成分の一斉分析による抗体高産生クローンの代謝解析2022
- Author(s)
  黒田博隆, 空田和也, 山野範子, 飯田順子, 鈴木崇, 本山賢人, 大政健史
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] チャイニーズハムスター肺細胞由来のiPS 細胞の樹立2022
- Author(s)
  藤岡晴生, 吉田貴美, 金井貴蓉, 山野ー足立範子, 古賀雄一, 大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] Exploring the production bottleneck of shark derived IgNAR antibodies produced in Chinese hamster ovary cells and its application2022
- Author(s)
  Xiaofang Lyu, Masayoshi Onitsuka, Noriko Yamano-Adachi, Yuichi Koga, and Takeshi Omasa
- Organizer
  The 27th Young Asian Biological Engineers' Community (YABEC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] CHO-K1 細胞"株を用いたSARS-CoV-2 ウイルス様粒子の生産2022
- Author(s)
  保木本達也, Nguyen Bich Thao, 金井貴蓉, 山野-足立範子, 大政健史
- Organizer
  第74回日本生物工学会
- Data Source
  KAKENHI-PROJECT-22H00276
[Presentation] 高増殖性新規生産宿主細胞Chinese hamster lung (CHL)-YN細胞の特徴とその培養制御2021
- Author(s)
  山野-足立範子，古藤隆衣，Sukwattananipaat Puriwat，國田紘夢，有島凜太郎，古賀雄一，大政健史
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Establishing CHL-YN cells to spread their wings to the world2021
- Author(s)
  Noriko Yamano-Adachi, Rintaro Arishima, Puriwat Sukwattananipaat, Takae Koto, Hiromu Kunita, Yuichi Koga, and Takeshi Omasa
- Organizer
  The 26th Symposium of Young Asian Biological Engineers' Community (YABEC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] CHL-YN細胞の重力沈降型小型灌流培養2021
- Author(s)
  國田紘夢, Sukwattananipaat Puriwat, 古賀雄一, 山野-足立範子, 大政健史
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] グルタミン不含有培地における新規生産宿主細胞CHL-YN細胞の培養解析2021
- Author(s)
  古藤隆衣, 山野-足立範子, 有島凛太郎, 古賀雄一, 大政健史
- Organizer
  日本動物細胞工学会2021
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] Development of monoclonal antibody producing Chinese hamster lung (CHL)-YN cells in serum-free fed-batch cultivation2021
- Author(s)
  Puriwat Sukwattananipaat, Noriko Yamano-Adachi, Yuichi Koga, Takeshi Omasa
- Organizer
  The 26th Symposium of Young Asian Biological Engineers' Community (YABEC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04788
[Presentation] ゲノム安定化を目指したCHO細胞におけるp21/p53遺伝子の機能解析2020
- Author(s)
  五百井風香，Christopher Quach，山野-足立範子，古賀雄一，大政健史
- Organizer
  化学工学会第85年会（紙面開催）
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] Establishment of IgG1 producing Chinese hamster ovary cells with the same vector integration site and number and with different chromosome number distribution between the sub-clones2020
- Author(s)
  Hirofumi Hata, Yuto Nakanishi, Wataru Tanaka, Yuichi Koga, Noriko Yamano-Adachi, Takeshi Omasa
- Organizer
  The 33rd Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2020 Fuchu)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] IgG生産細胞株構築における異数性CHO細胞の人為的誘導の効果2020
- Author(s)
  畑展史，中西悠人，田中航，古賀雄一，山野-足立範子，大政健史
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] IgG生産細胞株構築における異数性CHO細胞の人為的誘導の効果2020
- Author(s)
  畑展史，中西悠人，田中航，古賀雄一，山野-足立範子，大政健史
- Organizer
  化学工学会第85年会（紙面開催）
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] ゲノム安定化を目指したCHO細胞におけるp21/p53遺伝子の機能解析2020
- Author(s)
  五百井風香，Christopher Quach，山野-足立範子，古賀雄一，大政健史
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] The effect of telomere sequences on chromosomal translocations2019
- Author(s)
  Jun Ho Lee, Wataru Tanaka, Noriko Yamano, and Takeshi Omasa
- Organizer
  The 26th ESACT Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] Analysis of antibody productivity among Chinese hamster ovary cells constructed by Crispr/Cas9-mediated sitespecific integration2019
- Author(s)
  Yuto Nakanishi, Wataru Tanaka, Noriko Yamano-Adachi, Hirofumi Hata, Yuichi Koga and Takeshi Omasa
- Organizer
  Asian Congress on Biotechnology 2019 (ACB2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] Analysis of the interstitial telomeric sequences (ITSs) and chromosomal translocations in Cricetulus griseus-derived cells using FISH2018
- Author(s)
  Jun Ho Lee, Wataru Tanaka, Noriko Yamano, and Takeshi Omasa
- Organizer
  The 24th Symposium of Young Asian Biological Engineers' Community (YABEC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] Characterization of CHO cells with disparate chromosome numbers and induction of artificial aneuploidy cells2018
- Author(s)
  Noriko Yamano, Norichika Ogata, Yuan Shan Lai, Sho Tanaka, Wataru Tanaka, Yuichi Koga, Takeshi Omasa
- Organizer
  The 31th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2018 Tsukuba)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105
[Presentation] Analysis of chromosomal diversity in CHO cell lines for establishment of stable highly-productive cell line in recombinant therapeutics production2018
- Author(s)
  Kazuma Kita, Noriko Yamano, Yuichi Koga, and Takeshi Omasa
- Organizer
  The 24th Symposium of Young Asian Biological Engineers' Community (YABEC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21105

1. 大政健史 (00252586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
2. 鬼塚正義 (80571174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 太田誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamano Noriko 山野 範子

Research Projects

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Construction of mammalian cell-based cell and bioprocess engineering

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Whole genome analysis and construction of a karyotype image analysis system for novel biopharmaceutical production host cellsPrincipal Investigator

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Utilization of chromosomal instability in CHO cells in recombinant protein productionPrincipal Investigator

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[Journal Article] Construction of a novel kinetic model for the production process of a CVA6 VLP vaccine in CHO cells2024

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[Journal Article] Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones2024

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[Journal Article] 次世代型抗体生産のためのホスト細胞開発2023

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[Journal Article] Synthesis of Human Antibodies Against HBsAg in Newly Established Chinese Hamster Lung (CHL-YN) Cell Line2023

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[Journal Article] Recent advances in animal cell technologies for industrial and medical applications2022

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[Journal Article] Artificial induction of chromosome aneuploidy in CHO cells alters their function as host cells2022

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[Journal Article] 生物（細胞）にしかできないモノつくり2022

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[Journal Article] Effect of co-overexpression of the cargo receptor ERGIC-53/MCFD2 on antibody production and intracellular IgG secretion in recombinant Chinese hamster ovary cells2022

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[Journal Article] 組換えタンパク質生産における染色体不安定性の利用2021

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[Journal Article] 組換えタンパク質を生産するための優れた宿主細胞とは2021

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[Journal Article] 組換えタンパク質生産における染色体不安定性の利用2020

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Yamano Noriko 山野範子