Nakato Gaku 中藤学

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NAKATO Gaku 中藤学

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Researcher Number	20584535
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 地方独立行政法人神奈川県立産業技術総合研究所, 腸内環境デザイングループ, サブリーダー 2018 – 2020: 地方独立行政法人神奈川県立産業技術総合研究所, 「腸内細菌叢」プロジェクト, サブリーダー 2014: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 特別研究員 2010 – 2012: 独立行政法人理化学研究所, 免疫系構築研究チーム, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Immunology Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Immunology
Keywords	Principal Investigator 粘膜免疫 / 免疫細胞 / 腸管上皮細胞 / EpCAM / TROP2 / M細胞 / 杯細胞 / microRNA Except Principal Investigator 腸内細菌 / 持久力 … More / 運動 / メタボロゲノミクス / 短鎖脂肪酸 / 持久運動 / 腸内環境 / 代謝物質 / 腸管免疫 / サルモネラ / GP2 / Spi-B / 分化 / NFκB / RANKL / 免疫学 / 細菌感染 / シグナル伝達 / M細胞 / 上皮細胞 / 発生・分化 / 細胞・組織 / 粘膜免疫学 Less

上皮細胞接着分子EpCAM、TROP2機能解析による粘膜免疫構築メカニズム解明Principal Investigator
- Principal Investigator
  
  中藤学
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanagawa Institute of Industrial Sclence and Technology
Elucidation of the molecular basis for endurance exercise performance by gut microbiota-derived metabolites
- Principal Investigator
  
  福田真嗣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanagawa Institute of Industrial Sclence and Technology
How EpCAM and TROP2 function in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  Nakato Gaku
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanagawa Institute of Industrial Sclence and Technology
Comprehensive understanding of a unique intestinal epithelial M cells specialized for luminal particulate antigen uptake
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
腸管上皮細胞の分化及び恒常性維持におけるmiRNAの果たす役割の解明Principal Investigator
- Principal Investigator
  
  中藤学
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Epithelium-intrinsic microRNAs contribute to the mucosal immune homeostasis through ensuring epithelial cell differentiationPrincipal Investigator
- Principal Investigator
  
  NAKATO Gaku
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research

All 2020 2014 2012 2011 2010

All Journal Article Presentation Book

[Book] 細胞工学2011
- Author(s)
  長谷耕二、中藤学、大野博司
- Data Source
  KAKENHI-PROJECT-22890238
[Book] 分子消化器病2011
- Author(s)
  大野博司、長谷耕二、中藤学
- Data Source
  KAKENHI-PROJECT-22890238
[Book] 臨床免疫-アレルギー科2010
- Author(s)
  大野博司、長谷耕二、中藤学
- Data Source
  KAKENHI-PROJECT-22890238
[Journal Article] Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins2020
- Author(s)
  Chuanjin Wu, Micheal Lu, Xu Feng, Gaku Nakato, Mark C. Udey
- Journal Title
  
  cells
  
  Volume: 9(4) Issue: 4 Pages: 1027-1027
- DOI
  10.3390/cells9041027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07990
[Journal Article] Amelioration of Congenital Tufting Enteropathy in EpCAM (TROP1)-Deficient Mice via Heterotopic Expression of TROP2 in Intestinal Epithelial Cells2020
- Author(s)
  Gaku Nakato, Sohshi Morimura, Micheal Lu, Xu Feng, Chuanjin Wu, Mark C. Udey
- Journal Title
  
  cells
  
  Volume: 9(8) Issue: 8 Pages: 1847-1847
- DOI
  10.3390/cells9081847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07990
[Journal Article] Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues2014
- Author(s)
  Yuuki Obata, Shunsuke Kimura, Gaku Nakato, Keito Iizuka, Yurika Miyagawa, Yutaka Nakamura, Yukihiro Furusawa, Machiko Sugiyama, Keiichiro Suzuki, Masashi Ebisawa, Yumiko Fujimura, Hisahiro Yoshida, Toshihiko Iwanaga, Koji Hase and Hiroshi Ohno.
- Journal Title
  
  EMBO Reports
  
  Volume: 12 Issue: 12 Pages: 1297-1304
- DOI
  10.15252/embr.201438942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460261, KAKENHI-PUBLICLY-26116709
[Journal Article] Selection of an Aptamer against Mouse GP2 by SELEX2014
- Author(s)
  Hanazato, M., Nakato, G., Nishikawa, F., Hase, K., Nishikawa, S., Ohno, H.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 39 Issue: 1 Pages: 23-29
- DOI
  10.1247/csf.13019
- NAID
  130004053898
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249029
[Journal Article] Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development2012
- Author(s)
  Machiko Sugiyama, Gaku Nakato, Toshi Jinnohara, Hisaya Akiba, Ko Okumura, Hiroshi Ohno, and Hisahiro Yoshida
- Journal Title
  
  Int Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890238
[Journal Article] Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor.2012
- Author(s)
  Nakato G, Hase K, Suzuki M, Kimura M, Ato M, Hanazato M, Tobiume M, Horiuchi M, Atarashi R, Nishida N, Watarai M, Imaoka K, Ohno H
- Journal Title
  
  Journal of Immunology
  
  Volume: 189(4) Issue: 4 Pages: 1540-4
- DOI
  10.4049/jimmunol.1103332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591116, KAKENHI-PROJECT-22689017, KAKENHI-PROJECT-23248050, KAKENHI-PROJECT-23658233, KAKENHI-PROJECT-24249029, KAKENHI-PUBLICLY-24117723
[Presentation] Epithelium-intrinsic microRNAs contribute to the mucosal immune homeostasis through ensuring M cell differentiation2012
- Author(s)
  Gaku Nakato
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-24790485
[Presentation] Cellular prion protein on Peyer's patch M cells serves as an invasive receptor for Brucella abortus2012
- Author(s)
  Gaku Nakato and Hiroshi Ohno
- Organizer
  3rd Nagasaki Prion mini-symposium
- Place of Presentation
  Japan
- Year and Date
  2012-01-29
- Data Source
  KAKENHI-PROJECT-22890238
[Presentation] Cellular prion protein on Peyer's patch M cells serves as invasive receptor of a zoonotic pathogen Brucella abortus2011
- Author(s)
  Gaku Nakato, Koji Hase, Michio Suzuki, Noriyuki Nishida, Motohiro Horiuchi, Manabu Ato and Hiroshi Ohno
- Organizer
  第40回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22890238
[Presentation] Identification of RNA aptamers targeting mouse GP2 protein by SELEX2011
- Author(s)
  Misaho Hanazato, Gaku Nakato, Fumiko Nishikawa, Koji Hase, Satoshi Nishikawa, Hiroshi Ohno
- Organizer
  第34回日本分子生物学学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22890238
[Presentation] M細胞に発現する内在性プリオンタンパク質はBrucella abortusの取り込み受容体として機能する2011
- Author(s)
  中藤学、長谷耕二、鈴木道雄、木村昌伸、新竜一郎、西田教行、度会雅久、今岡浩一、大野博司
- Organizer
  第9回感染症沖縄フォーラム
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-22890238
[Presentation] Distinct miRNA expression profiles of Follicle-associated epithelium(FAE) and villous epithelium(VE)2010
- Author(s)
  Gaku Nakato, Koji Hase and Hiroshi Ohno
- Organizer
  The 19th CDB Meeting RNA Sciences in Cell and Development Biology Kobe
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-22890238

1. OHNO Hiroshi (50233226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KANATA Takashi (20553829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 福田真嗣 (80435677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 尾花望 (00722688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 加藤守匡 (20399330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 飛梅実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 阿戸学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakato Gaku 中藤 学

NAKATO Gaku 中藤 学

Research Projects

Research Products

Co-Researchers

上皮細胞接着分子EpCAM、TROP2機能解析による粘膜免疫構築メカニズム解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular basis for endurance exercise performance by gut microbiota-derived metabolites

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How EpCAM and TROP2 function in the gastrointestinal tractPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive understanding of a unique intestinal epithelial M cells specialized for luminal particulate antigen uptake

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腸管上皮細胞の分化及び恒常性維持におけるmiRNAの果たす役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epithelium-intrinsic microRNAs contribute to the mucosal immune homeostasis through ensuring epithelial cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞工学2011

Author(s)

Data Source

[Book] 分子消化器病2011

Author(s)

Data Source

[Book] 臨床免疫-アレルギー科2010

Author(s)

Data Source

[Journal Article] Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amelioration of Congenital Tufting Enteropathy in EpCAM (TROP1)-Deficient Mice via Heterotopic Expression of TROP2 in Intestinal Epithelial Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selection of an Aptamer against Mouse GP2 by SELEX2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development2012

Author(s)

Journal Title

Data Source

[Journal Article] Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor.2012

Author(s)

Journal Title

Nakato Gaku 中藤学

NAKATO Gaku 中藤学