sugiura koji 杉浦幸二

… Alternative Names

Sugiura Koji 杉浦幸二

SUGIURA KOJI 杉浦幸二

Less

Researcher Number	20595623
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2017: 東京大学, 農学生命科学研究科, 准教授 2012 – 2014: 東京大学, 農学生命科学研究科, 准教授
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Animal production science / Integrative animal science / Biological Sciences / Applied animal science Except Principal Investigator Integrative animal science
Keywords	Principal Investigator 卵巣 / エクソソーム / 繁殖 / 卵母細胞 / 卵巣卵胞 / 卵巣疾患 / 卵 / 加齢 / 細胞老化 / 卵管 … More / セネッセンス / ブタ / エストロゲン / FOXL2 … More Except Principal Investigator 哺乳類卵 / 魚卵 / CRISPR/Cas / Cas9 / 魚類卵 / ブタ卵 / マウス卵 / ZFN / CRISPR / 人工ヌクレアーゼ Less

Investigating the cause of livestock breeding disorders: elucidation of ovarian control mechanisms by exosomes.Principal Investigator
- Principal Investigator
  
  杉浦幸二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  The University of Tokyo
The study of the mechanism how the exercise affects ovarian functions.Principal Investigator
- Principal Investigator
  
  Sugiura Koji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Ovarian dysfunction related to exosomal deficiencyPrincipal Investigator
- Principal Investigator
  
  Sugiura Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  The University of Tokyo
The study of the effects of cellular senesce on female reproductive tractsPrincipal Investigator
- Principal Investigator
  
  Sugiura Koji
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
The study of the regulation of ovarian development and function by follicular exosome.Principal Investigator
- Principal Investigator
  
  Sugiura Koji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Animal production science
- Research Institution
  The University of Tokyo
Regulation of ovarian fuctions through exosome-mediated inter-organ communicationsPrincipal Investigator
- Principal Investigator
  
  Sugiura Koji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
哺乳類生殖巣の雌性維持機構の解明Principal Investigator
- Principal Investigator
  
  杉浦幸二
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Study on practical application of zinc finger nuclease for gene knockout animal production
- Principal Investigator
  
  Naito Kunihiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
The study of novel mechanism for oocyte development regulated by signal interaction.Principal Investigator
- Principal Investigator
  
  SUGIURA KOJI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied animal science
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Dynamics of extracellular vesicle uptake by mural granulosa cells in mice2024
- Author(s)
  Edure Taichi、Matsuno Yuta、Matsushita Kodai、Maruyama Natsumi、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 91 Issue: 3
- DOI
  10.1002/mrd.23737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19183
[Journal Article] Accumulation of senescent cells in the stroma of aged mouse ovary2023
- Author(s)
  MARUYAMA Natsumi、FUKUNAGA Isuzu、KOGO Tomoaki、ENDO Tsutomu、FUJII Wataru、KANAI-AZUMA Masami、NAITO Kunihiko、SUGIURA Koji
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 69 Issue: 6 Pages: 328-336
- DOI
  10.1262/jrd.2023-021
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19183
[Journal Article] The effect of ACVR1B/TGFBR1/ACVR1C signaling inhibition on oocyte and granulosa cell development during in vitro growth culture2023
- Author(s)
 AKIMOTO Yuki、FUJII Wataru、NAITO Kunihiko、SUGIURA Koji
- Journal Title
 
 J. Reprod. Dev.
 
 Volume: 69 Issue: 5 Pages: 270-278
- DOI
 10.1262/jrd.2023-041
- ISSN
 0916-8818, 1348-4400
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K19183
[Journal Article] Paracrine regulation of granulosa cell development in the antral follicles in mammals2023
- Author(s)
  Sugiura Koji、Maruyama Natsumi、Akimoto Yuki、Matsushita Kodai、Endo Tsutomu
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 22 Issue: 1
- DOI
  10.1002/rmb2.12538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19183
[Journal Article] Cooperative effects of oocytes and estrogen on the forkhead box L2 expression in mural granulosa cells in mice2022
- Author(s)
  Ito Haruka、Emori Chihiro、Kobayashi Mei、Maruyama Natsumi、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20158-20158
- DOI
  10.1038/s41598-022-24680-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19183, KAKENHI-PROJECT-20H03124
[Journal Article] Effect of fibroblast growth factor signaling on cumulus expansion in mice in vitro2022
- Author(s)
  Kanke Takuya、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 89 Issue: 7 Pages: 281-289
- DOI
  10.1002/mrd.23616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03124, KAKENHI-PROJECT-21J13556
[Journal Article] Expression and regulation of estrogen receptor 2 and its coregulators in mouse granulosa cells2022
- Author(s)
  EMORI Chihiro, KANKE Takuya, ITO Haruka, AKIMOTO Yuki, FUJII Wataru, NAITO Kunihiko, SUGIURA Koji
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 68 Issue: 2 Pages: 137-143
- DOI
  10.1262/jrd.2021-114
- NAID
  130008142259
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J14275, KAKENHI-PROJECT-21K19183, KAKENHI-PROJECT-20H03124
[Journal Article] 卵分泌因子による卵巣顆粒膜細胞の分化制御機構2021
- Author(s)
  伊藤遥，杉浦幸二
- Journal Title
  
  Journal of Mammalian Ova Research
  
  Volume: 38 Pages: 31-38
- Data Source
  KAKENHI-PROJECT-21K19183
[Journal Article] 卵分泌因子による卵巣顆粒膜細胞の分化制御機構2021
- Author(s)
  伊藤遥，杉浦幸二
- Journal Title
  
  Journal of Mammalian Ova Research
  
  Volume: 38 Pages: 31-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03124
[Journal Article] Oocytes suppress FOXL2 expression in cumulus cells in mice†2020
- Author(s)
  Emori Chihiro、Ito Haruka、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  Biology of Reproduction
  
  Volume: 103 Issue: 1 Pages: 85-93
- DOI
  10.1093/biolre/ioaa054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J14275, KAKENHI-PROJECT-20H03124
[Journal Article] Effects of oocyte‐derived paracrine factors on release of extracellular vesicles by murine mural granulosa cells in vitro2020
- Author(s)
  Matsuno Yuta、Maruyama Natsumi、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  Animal Science Journal
  
  Volume: 91 Issue: 1
- DOI
  10.1111/asj.13385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03124
[Journal Article] Expression of genes involved in the non-neuronal cholinergic system and their possible functions during ovarian follicular development in mice.2019
- Author(s)
  Ueno M, Ito H, Kanke T, Matsuno Y, Fujii W, Naito K, Sugiura K.
- Journal Title
  
  J. Mamm. Ova Res.
  
  Volume: 35 Pages: 61-69
- NAID
  40022065358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03900
[Journal Article] Expression and function of exportin 6 in full-grown and growing porcine oocytes2019
- Author(s)
  ONUMA Asuka、FUJIOKA Yoshie A.、FUJII Wataru、SUGIURA Koji、NAITO Kunihiko
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 5 Pages: 407-412
- DOI
  10.1262/jrd.2019-040
- NAID
  130007732104
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03900
[Journal Article] Generation of genetically modified mice using SpCas9-NG engineered nuclease2019
- Author(s)
  Fujii Wataru、Ito Haruka、Kanke Takuya、Ikeda Arisa、Sugiura Koji、Naito Kunihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 12878-12878
- DOI
  10.1038/s41598-019-49394-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03900, KAKENHI-PROJECT-19J22776, KAKENHI-PROJECT-18K19261
[Journal Article] Characterization of mRNA profiles of the exosome-like vesicles in porcine follicular fluid2019
- Author(s)
  Matsuno Yuta、Kanke Takuya、Maruyama Natsumi、Fujii Wataru、Naito Kunihiko、Sugiura Koji
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 6 Pages: e0217760-e0217760
- DOI
  10.1371/journal.pone.0217760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03900, KAKENHI-PROJECT-18K19263
[Journal Article] High-fidelity endonuclease variant HypaCas9 facilitates accurate allele-specific gene modification in mouse zygotes2019
- Author(s)
  Ikeda Arisa、Fujii Wataru、Sugiura Koji、Naito Kunihiko
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 371-371
- DOI
  10.1038/s42003-019-0627-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03900, KAKENHI-PROJECT-19J22776, KAKENHI-PROJECT-18K19261
[Journal Article] Contributions of UBE2C and UBE2S to meiotic progression of porcine oocytes2018
- Author(s)
  Fujioka YA, Onuma A, Fujii W, Sugiura K, Naito K.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 3 Pages: 253-259
- DOI
  10.1262/jrd.2018-006
- NAID
  130007409956
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-17H03900
[Journal Article] Efficient mutagenesis by CRISPR/Cas system during meiotic maturation of porcine oocytes2017
- Author(s)
  Onuma A, Fujii W, Sugiura K, Naito K.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 63 Issue: 1 Pages: 45-50
- DOI
  10.1262/jrd.2016-094
- NAID
  130005332294
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-15K14884, KAKENHI-PROJECT-26712025
[Journal Article] Efficient generation of genome-modified mice using Campylobacter jejuni-derived CRISPR/Cas.2017
- Author(s)
  Fujii W, Ikeda A, Sugiura K, Naito K.
- Journal Title
  
  International Jornal of Molecular Sciences
  
  Volume: 18 Issue: 11 Pages: 2286-2286
- DOI
  10.3390/ijms18112286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-26712025
[Journal Article] Effects of exosome-like vesicles on cumulus expansion in pigs in vitro2017
- Author(s)
 Matsuno Y, Onuma A, Fujioka YA, Yasuhara K, Fujii W, Naito K, Sugiura K.
- Journal Title
 
 J. Reprod. Dev.
 
 Volume: 63 Issue: 1 Pages: 51-58
- DOI
 10.1262/jrd.2016-124
- NAID
 130005332300
- ISSN
 0916-8818, 1348-4400
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-16K15052
[Journal Article] Analyses of EMI functions on meiotic maturation of porcine oocytes.2016
- Author(s)
  Fujioka YA, Onuma A, Fujii W, Sugiura K, Naito K.
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 83 Issue: 11 Pages: 983-992
- DOI
  10.1002/mrd.22738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25252056
[Journal Article] Effects of porcine oocytes on the expression levels of transcripts encoding glycolytic enzymes in granulosa cells.2016
- Author(s)
  Matsuno Y, Onuma A, Fujioka YA, Emori C, Fujii W, Naito K, Sugiura K.
- Journal Title
  
  Anim Sci J
  
  Volume: 未定 Issue: 9 Pages: 1114-1121
- DOI
  10.1111/asj.12539
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25132704
[Journal Article] Zygote-mediated generation of genome-modified mice using Streptococcus thermophiles 1-derived CRISPR/Cas system.2016
- Author(s)
  Fujii W, Kakuta S, Yoshioka S, Kyuwa S,Sugiura K,Naito K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 477 Issue: 3 Pages: 473-476
- DOI
  10.1016/j.bbrc.2016.06.070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-15K14884, KAKENHI-PROJECT-26712025
[Journal Article] Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles.2015
- Author(s)
  Wigglesworth K, Lee KB, Emori C, Sugiura K, Eppig JJ
- Journal Title
  
  Biol Reprod
  
  Volume: 92 Pages: 23-23
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-25132704
[Journal Article] Development of a mono-promoter-driven CRISPR/Cas9 system in mammalian cells2015
- Author(s)
  Shin Yoshioka, Wataru Fujii, Tetsuhiro Ogawa, Koji Sugiura, and Kunihiko Naito
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 18341-18341
- DOI
  10.1038/srep18341
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14884, KAKENHI-PROJECT-15J01244, KAKENHI-PROJECT-26712025, KAKENHI-PROJECT-25252056
[Journal Article] Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes2015
- Author(s)
 Fujii W, Onuma A, Yoshioka S, Nagashima K, Sugiura K, Naito K
- Journal Title
 
 J. Reprod. Dev.
 
 Volume: 61 Issue: 6 Pages: 589-593
- DOI
 10.1262/jrd.2015-087
- NAID
 130005113567
- ISSN
 0916-8818, 1348-4400
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-26712025, KAKENHI-PROJECT-25252056
[Journal Article] Efficient generation of genome-modified mice via offset-nicking by CRISPR/Cas system.2014
- Author(s)
  Fujii W, Onuma A, Sugiura K, Naito K.
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume: 445 Issue: 4 Pages: 791-794
- DOI
  10.1016/j.bbrc.2014.01.141
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-25892010
[Journal Article] One-step Generation of Phenotype-expressing Triple-knockout Mice with Heritable Mutated Alleles by the CRISPR/Cas9 System2014
- Author(s)
  Fujii W, Onuma A, Sugiura K, Naito K.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 60 Issue: 4 Pages: 324-327
- DOI
  10.1262/jrd.2013-139
- NAID
  130004137824
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-26712025
[Journal Article] 卵胞発達における卵母細胞由来の増殖因子の役割2014
- Author(s)
  江森千紘、川崎紅、杉浦幸二
- Journal Title
  
  日本IVF学会雑誌
  
  Volume: 17巻1号
- Data Source
  KAKENHI-PROJECT-24780267
[Journal Article] Cytoplasmic Anchoring of cAMP-Dependent Protein Kinase (PKA) by A-Kinase Anchor Proteins (AKAPs) Is Required for Meiotic Arrest of Porcine Full-Grown and Growing Oocytes2014
- Author(s)
  Nishimura T, Fujii W, Sugiura K, Naito K
- Journal Title
  
  Biol Reprod
  
  Volume: 90 Issue: 3
- DOI
  10.1095/biolreprod.113.114736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380147, KAKENHI-PROJECT-25252056
[Journal Article] Cooperative effects of 17β-estradiol and oocyte-derived paracrine factors on the transcriptome of mouse cumulus cells2013
- Author(s)
  Emori C, Wigglesworth K, Fujii W, Naito K, Eppig JJ, Sugiura K
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 4859-4872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780267
[Journal Article] Repeatable Construction Method for Engineered Zinc Finger Nuclease Based on2013
- Author(s)
  Wataru Fujii
- Journal Title
  
  PloS ONE
  
  Volume: 8 Issue: 3 Pages: e59801-e59801
- DOI
  10.1371/journal.pone.0059801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02886, KAKENHI-PROJECT-25252056
[Journal Article] Cooperative effects of 17β-estradiol and oocyte-derived paracrine factors on the transcriptome of mouse cumulus cells.2013
- Author(s)
  Emori C, Wigglesworth K, Fujii W, Naito K, Eppig JJ, Sugiura K
- Journal Title
  
  Endocrinology
  
  Volume: 154 Issue: 12 Pages: 4859-4872
- DOI
  10.1210/en.2013-1536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780267, KAKENHI-PUBLICLY-25132704
[Journal Article] Hormonal Coordination of Natriuretic Peptide Type C and Natriuretic Peptide Receptor 3 Expression in Mouse Granulosa Cells2013
- Author(s)
  Lee KB, Zhang M, Sugiura K, Wigglesworth K, Uliasz T, Jaffe LA, Eppig JJ
- Journal Title
  
  Biol. Reprod
  
  Volume: 88 Pages: 42-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780267
[Journal Article] Efficient generation of large-scale genome-modified-mice using gRNA and CAS9 endonuclease.2013
- Author(s)
  Fujii W, Kawasaki K, Sugiura K, Naito K.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 41 Issue: 20 Pages: e187-e187
- DOI
  10.1093/nar/gkt772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-25892010
[Journal Article] Role of oocyte-derived paracrine factors in follicular development
- Author(s)
  Emori C, Sugiura K
- Journal Title
  
  Anim. Sci. J
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] 卵巣顆粒層細胞による細胞外小胞の取り込み機構の研究2023
- Author(s)
  杉浦幸二、江連泰知、松野雄太、藤井渉、内藤邦彦
- Organizer
  第131回日本畜産学会大会（帯広畜産大学）
- Data Source
  KAKENHI-PROJECT-21K19183
[Presentation] 胞状卵胞発達を支える細胞間コミュニケーション2022
- Author(s)
  杉浦幸二
- Organizer
  第63回日本卵子学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03124
[Presentation] Effect of fibroblast growth factor signaling on cumulus expansion in mice in vitro.2021
- Author(s)
  Kanke T, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19183
[Presentation] ALK5-SMAD2/3 signaling in granulosa cells is required for the acquisition of the oocyte developmental competence.2021
- Author(s)
  Akimoto Y, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19183
[Presentation] ALK5-SMAD2/3 signaling in granulosa cells is required for the acquisition of the oocyte developmental competence2021
- Author(s)
  Akimoto Y, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03124
[Presentation] Senescent cells accumulate in ovarian stromal region of aged mice.2021
- Author(s)
  Maruyama N, Fukunaga I, Kogo T, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19183
[Presentation] Effect of fibroblast growth factor signaling on cumulus expansion in mice in vitro.2021
- Author(s)
  Kanke T, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03124
[Presentation] Senescent cells accumulate in ovarian stromal region of aged mice.2021
- Author(s)
  Maruyama N, Fukunaga I, Kogo T, Fujii W, Naito K, Sugiura K.
- Organizer
  54th Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03124
[Presentation] 哺乳類卵管の老化：加齢に伴う繁殖能力低下メカニズム2020
- Author(s)
  丸山夏海, 福長一鈴, 藤井渉, 内藤邦彦, 杉浦幸二
- Organizer
  第20回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K19263
[Presentation] マウス卵胞発達にエクソソームが果たす役割に関する研究2019
- Author(s)
  丸山夏海, 松野雄太, 藤井渉, 内藤邦彦, 杉浦幸二
- Organizer
  第19回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K19263
[Presentation] Appropriate regulation of Noggin expression in follicles is critical for female fertility in mice.2018
- Author(s)
  Sugiura K, Emori C, Kogo T, Kanke T, Ito H, Fujii W, Naito K.
- Organizer
  51st Annual meeting of society for the study of reproduction
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] A model for studying transdifferentiation of granulosa cells into Sertoli-like cells in mice.2018
- Author(s)
  Ito H, Kishi K, Emori C, Fujii W, Kanai Y, Naito K, Sugiura K
- Organizer
  51st Annual meeting of society for the study of reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] Mouse granulosa cells secrete functional extracellular vesicles in vitro2017
- Author(s)
  Matsuno Y, Fujii W, Natio K, Sugiura K.
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15052
[Presentation] Mouse granulosa cells secrete functional extracellular vesicles in vitro2017
- Author(s)
  Matsuno Y, Fujii W, Natio K, Sugiura K.
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] Possibility of transdifferentiating mouse granulosa cells into Sertoli-like cells in vitro.2017
- Author(s)
  Ito H, Emori C, Fujii W, Naito K, Sugiura K
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] C. jejuni由来CRISPR/Casによるゲノム改変マウスの作製2017
- Author(s)
  藤井渉・池田有沙・杉浦幸二・内藤邦彦
- Organizer
  第123回日本畜産学会
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] Mouse granulosa cells secrete exosomes independently of oocyte regulation in vitro2017
- Author(s)
  松野雄太、Dang Quoc Thuyet、藤井渉、大下誠一、内藤邦彦、杉浦幸二
- Organizer
  第123回日本畜産学会
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] Senescence in ovarian cells2017
- Author(s)
  福長一鈴、向後智明、藤井渉、内藤邦彦、杉浦幸二
- Organizer
  第123回日本畜産学会
- Data Source
  KAKENHI-PROJECT-17H03900
[Presentation] Mouse granulosa cells secrete exosomes independently of oocyte regulation in vitro2017
- Author(s)
  松野雄太、Dang Quoc Thuyet、藤井渉、大下誠一、内藤邦彦、杉浦幸二
- Organizer
  第123回日本畜産学会
- Data Source
  KAKENHI-PROJECT-16K15052
[Presentation] ブタ卵母細胞成熟過程における核外移行因子exportin-1の機能解析2016
- Author(s)
  小沼あすか・藤井　渉・杉浦幸二・内藤邦彦
- Organizer
  第121回日本畜産学会
- Place of Presentation
  日本獣医生命科学大学（東京都武蔵野市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] 卵分泌因子と卵胞発育2015
- Author(s)
  杉浦幸二
- Organizer
  第６回金沢大学学際科学実験センターシンポジウム
- Place of Presentation
  金沢大学
- Year and Date
  2015-11-13
- Invited
- Data Source
  KAKENHI-PUBLICLY-25132704
[Presentation] CRISPR/Casシステムを利用したゲノム改変マウス作製法の開発2015
- Author(s)
  藤井渉・杉浦幸二・内藤邦彦
- Organizer
  第16回日本動物遺伝育種学会
- Place of Presentation
  神戸大学（兵庫県神戸市）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] ドナーDNA条件がCRISPR/Casによるマウス前核期卵のノックインに与える影響2015
- Author(s)
  永島圭介・藤井　渉・杉浦幸二・内藤邦彦
- Organizer
  第15回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] Mouse oocytes maintain FOXL2 expression in granulosa cells in coordination with estrogen.2015
- Author(s)
  mori C, Fujii W, Naito K, Sugiura K
- Organizer
  48th Annual meeting of society for the study of reproduction
- Place of Presentation
  Puerto Rico, USA
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-25132704
[Presentation] オフセットニッキング法によるゲノム改変マウスの作製2014
- Author(s)
  藤井　渉・小沼　あすか・杉浦　幸二・内藤　邦彦
- Organizer
  第118回日本畜産学会
- Place of Presentation
  つくば国際会議場（エポカルつくば）（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] ブタ卵胞液におけるエキソソームの存在確認2014
- Author(s)
  松野雄太,藤井渉,内藤邦彦,杉浦幸二
- Organizer
  第118回日本畜産学会
- Place of Presentation
  につくば国際会議場
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] マウス個体の老化が卵母細胞と卵丘細胞間のコミュニケーションに及ぼす影響2013
- Author(s)
  川崎紅,藤井渉,内藤邦彦,杉浦幸二
- Organizer
  第106回日本繁殖生物学会
- Place of Presentation
  東京農工大学
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] Oocyte-derived BMP15/GDF9 and Estrogen reciprocally regulate Nog expression in cumulus cells to control intrafollicular BMP signals2013
- Author(s)
  Emori C, Naito K, Sugiura K
- Organizer
  Annual meeting of society for the study of reproduction
- Place of Presentation
  Montréal, Québec, Canada
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] マウス卵母細胞が顆粒膜細胞でのmiR-322発現を抑制する2013
- Author(s)
  住友準一,藤井渉,内藤邦彦,杉浦幸二
- Organizer
  第106回日本繁殖生物学会
- Place of Presentation
  東京農工大学
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] 卵-顆粒膜細胞間コミュニケーション2013
- Author(s)
  杉浦幸二
- Organizer
  第16回　日本IVF学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Invited
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] 最適化されたCAS9/gRNAシステムによるゲノム改変マウスの作製2013
- Author(s)
  藤井　渉・川崎　紅・杉浦　幸二・内藤　邦彦
- Organizer
  第106回日本繁殖生物学会
- Place of Presentation
  東京農工大学(東京都府中市）
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] マウス卵巣におけるFGFリガンドおよびレセプターの発現解析2012
- Author(s)
  古川最一,西村鷹則,藤井渉,内藤邦彦,杉浦幸二
- Organizer
  第105回日本繁殖生物学会
- Place of Presentation
  筑波大学
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] マウス卵胞発達におけるNogginの発現制御および機能解析(IYS-02)2012
- Author(s)
  江森千紘,内藤邦彦,杉浦幸二
- Organizer
  第116回日本畜産学会
- Place of Presentation
  安田女子大学、広島
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] ドナーDNA の状態がCRISPR/Casを用いたマウス前核期卵へのノックインに及ぼす影響
- Author(s)
  永島圭介・藤井　渉・杉浦幸二・内藤邦彦
- Organizer
  第119回日本畜産学会
- Place of Presentation
  宇都宮大学
- Year and Date
  2015-03-28 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] マウス卵胞発達過程におけるNogginの発現制御および機能解析
- Author(s)
  江森千紘，内藤邦彦，杉浦幸二
- Organizer
  第116回日本畜産学会
- Place of Presentation
  安田女子大学（広島県）
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] ブタ卵母細胞の減数分裂過程におけるFBXO5（EMI1）およびFBXO43（EMI2）の関与
- Author(s)
  藤岡良江・藤井　渉・杉浦　幸二・内藤邦彦
- Organizer
  第107回日本繁殖生物学会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2014-08-20 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] Oocyte-derived BMP15/GDF9 and estrogen reciprocally regulate Nog expression in cumulus cells to control intrafollicular BMP signals
- Author(s)
  Chihiro Emori, Kunihiko Naito, Koji Sugiura
- Organizer
  Society for the study of reproduction
- Place of Presentation
  カナダ、モントリオール
- Data Source
  KAKENHI-PROJECT-24780267
[Presentation] CRISPR/Casシステムを用いたブタ卵成熟過程におけるゲノム改変効率の検討
- Author(s)
  小沼あすか・藤井　渉・杉浦幸二・内藤邦彦
- Organizer
  第107回日本繁殖生物学会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2014-08-20 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25252056
[Presentation] Cooperative activities of oocyte-derived paracrine factors and estrogen on cumulus cell proliferation and metabolism
- Author(s)
  Chihiro Emori, Karen Wigglesworth, Kunihiko Naito, John J. Eppig, and Koji Sugiura.
- Organizer
  Society for the study of reproduction
- Place of Presentation
  アメリカ合衆国、ペンシルバニア州
- Data Source
  KAKENHI-PROJECT-24780267

1. Naito Kunihiko (20188858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. Yoshizaki Goro (70281003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Kikuchi Kazuhiro (20360456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 城口克之 (00454059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤井渉 (40708161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results

sugiura koji 杉浦 幸二

Sugiura Koji 杉浦 幸二

SUGIURA KOJI 杉浦 幸二

Research Projects

Research Products

Co-Researchers

Investigating the cause of livestock breeding disorders: elucidation of ovarian control mechanisms by exosomes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the mechanism how the exercise affects ovarian functions.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ovarian dysfunction related to exosomal deficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the effects of cellular senesce on female reproductive tractsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the regulation of ovarian development and function by follicular exosome.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of ovarian fuctions through exosome-mediated inter-organ communicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

哺乳類生殖巣の雌性維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on practical application of zinc finger nuclease for gene knockout animal production

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of novel mechanism for oocyte development regulated by signal interaction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dynamics of extracellular vesicle uptake by mural granulosa cells in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accumulation of senescent cells in the stroma of aged mouse ovary2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] The effect of ACVR1B/TGFBR1/ACVR1C signaling inhibition on oocyte and granulosa cell development during <i>in vitro</i> growth culture2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Paracrine regulation of granulosa cell development in the antral follicles in mammals2023

sugiura koji 杉浦幸二

Sugiura Koji 杉浦幸二

SUGIURA KOJI 杉浦幸二