Adachi Haruyo 足立はるよ (中嶋はるよ)

… Alternative Names

中嶋はるよ

Nakajima-Adachi Haruyo 足立はるよ

ADACHI Haruyo 足立はるよ

NAKAJIMA Haruyo 足立はるよ

Less

Researcher Number	20595962
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授
Affiliation (based on the past Project Information) *help	2024: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授 2018 – 2022: 東京大学, 大学院農学生命科学研究科(農学部), 特任助教 2016: 東京大学, 農学生命科学研究科, 特任助教 2013: 東京大学, 農学生命科学研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related Except Principal Investigator Food science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 骨量減少 / 腸内細菌 / 制御性T細胞 / 消化管アレルギーモデル / 組織常在性記憶T細胞 / osteoclast / bone loss / ovalbmin / intestinal inflammation / food allergy … More / 卵白アルブミン / OVA23-3マウス / 記憶T細胞 / 活性化T細胞 / 腸管膜リンパ節 / 腸炎惹起性記憶T細胞 / CD69 / 破骨細胞 / IL-4 / 食物アレルギー性小腸炎 / 消化管アレルギー … More Except Principal Investigator 樹状細胞 / 制御性T細胞 / 食品 / 機能性食品 / 腸管免疫系 / 免疫機能 / 疾患モデル / 定着能向上大腸菌 / プロバイオティクス / バイオフィルム / 消化管定着 / 腸内細菌 / 加齢 / 腸管バリア / マクロファージ / 脂肪組織 / 加齢性炎症 / 慢性炎症 / 濾胞性ヘルパーT細胞 / 濾胞性T細胞 / 乳酸菌 / 腸管免疫 / 食品免疫 / 食品機能 / 感染防御 / 制御性Ｔ細胞 / 経口免疫寛容 / TLR / IgA抗体 / 腸内共生菌 Less

Functional analysis of tissue-resident memory regulatory T cells of the intestine in bone loss associated with gastrointestinal allergy.Principal Investigator
- Principal Investigator
  
  足立はるよ (中嶋はるよ)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Development of novel technology for regulating biological functions via colonization-improved E. coli: in vivo trial using disease model animal
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Analysis of function of pathogenic-memory T cells on bone loss combined with food allergic enteropahyPrincipal Investigator
- Principal Investigator
  
  Nakajima-Adachi Haruyo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Regulation of chronic inflammation in aging and adipose tissues via the intestinal immune system by food
- Principal Investigator
  
  HACHIMURA Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Immunomodulation by foods based on elucidation of novel interactions of intestinal immune cells
- Principal Investigator
  
  HACHIMURA Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Elucidation of recognition and response of intestinal immune cells to microbes in relation to development of immunomodulating functional foods
- Principal Investigator
  
  HACHIMURA SATOSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo

All 2021 2020 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells2020
- Author(s)
  Takano Tomohiro、Kotaki Ryutaro、Park Jihyun、Yoshida Tadashi、Wakatsuki Yoshio、Tanokura Masaru、Miyakawa Takuya、Takahashi Kyoko、Nakajima-Adachi Haruyo、Hachimura Satoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1555-1555
- DOI
  10.3389/fimmu.2020.01555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21293, KAKENHI-PROJECT-18H02152
[Journal Article] <i>Lactobacillus plantarum</i> OLL2712 induces IL-10 production by intestinal dendritic cells2020
- Author(s)
  Takano T, Endo R, Wang Y, Nakajima-Adachi H, Hachimura S.
- Journal Title
  
  Bioscience of Microbiota, Food and Health
  
  Volume: 39 Issue: 2 Pages: 39-44
- DOI
  10.12938/bmfh.19-019
- NAID
  130007829979
- ISSN
  2186-3342
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02152
[Journal Article] Induction of Oral Tolerance by Pepsin-Digested Gliadin Retaining T Cell Reactivity in a Mouse Model of Wheat Allergy.2020
- Author(s)
  Li X, Miyakawa T, Takano T, Nakajima-Adachi H, Tanokura M, Hachimura S.
- Journal Title
  
  Int Arch Allergy Immunol.
  
  Volume: - Issue: 6 Pages: 446-455
- DOI
  10.1159/000506945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02152
[Journal Article] Intestinal regulatory T cell induction by β-elemene alleviates the formation of fat tissue-related inflammation.2020
- Author(s)
  Zhou Y, Takano T, Wang Y, Li X, Wang R, Wakatsuki Y, Nakajima-Adachi H, Tanokura M, Miyakawa T, Hachimura S.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 1 Pages: 101883-101883
- DOI
  10.1016/j.isci.2020.101883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02152
[Journal Article] Critical role of intestinal interleukin-4 modulating regulatory T Cells for desensitization, tolerance, and inflammation of food allergy.2017
- Author(s)
  Nakajima-Adachi, H., Shibahara, K., Fujimura, Y., Takeyama, J., Hiraide, E., Kikuchi, A., Murakami, H., Hosono, A., Nochi, T., Wakatsuki, Y., Shimojo, N., Kaminogawa, S., Sato, R., Kiyono, H. and Hachimura, S.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 2 Pages: e0172795-e0172795
- DOI
  10.1371/journal.pone.0172795
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-16H06207, KAKENHI-PROJECT-26292065, KAKENHI-PROJECT-26660245, KAKENHI-PROJECT-15K07443
[Journal Article] Attenuation of migration properties of CD4+ T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid and RALDH expression compared to young mice.2014
- Author(s)
  Park, J., Miyakawa, T., Shiokawa, A., Nakajima-Adachi, H., Tanokura, M., Hachimura, S.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: N/A
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380073
[Journal Article] Oral Administration of Lactobacillus plantarum Strain AYA Enhances IgA Secretion and Provides Survival Protection against Influenza Virus Infection in Mice.2014
- Author(s)
  Kikuchi, Y., Kunitoh-Asari, A., Hayakawa, K., Imai, S., Kasuya, K., Abe, K., Adachi, Y., Fukudome, S., Takahashi, Y., Hachimura, S.
- Journal Title
  
  PLoSONE
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380073
[Journal Article] Attenuation of migration properties of CD4+ T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid and RALDH expression compared to young mice2014
- Author(s)
  Park, J., Miyakawa, T., Shiokawa, A., Nakajima-Adachi, H., Tanokura, M., Hachimura, S
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380073
[Journal Article] Oral Administration of Lactobacillus plantarum Strain AYA Enhances IgA Secretion and Provides Survival Protection against Influenza Virus Infection in Mice2014
- Author(s)
  Kikuchi, Y., Kunitoh-Asari, A., Hayakawa, K., Imai, S., Kasuya, K., Abe, K., Adachi, Y., Fukudome, S., Takahashi, Y., Hachimura, S
- Journal Title
  
  PLoS ONE
  
  Volume: 9, e86416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380073
[Presentation] 消化管アレルギーモデルマウスに併発する骨量減少に対する制御性T細胞(Treg)の影響2021
- Author(s)
  曽我皓平、宇野智、玉井雅人、中村翔太朗、伊藤明美、八村敏志、足立(中嶋)はるよ
- Organizer
  日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K05502
[Presentation] Lactobacillus plantarum OLL2712株の経口投与が高脂肪食を摂取したマウス体内における抗炎症作用を発揮する経路の検討.2021
- Author(s)
  王イバイ，高野智弘，周英ギョク，王蓉，田之倉優，宮川拓也，足立（中嶋）はるよ，八村敏志
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18H02152
[Presentation] Intestinal Regulatory T Cell Induction by β-Elemene Alleviates the Formation of Fat Tissue-Related Inflammation.2021
- Author(s)
  ZHOU Yingyu，TAKANO Tomohiro，WANG Yimei， LI Xuyang，WANG Rong，WAKATSUKI Yoshio，ADACHI(NAKAJIMA) Haruyo，TANOKURA Masaru， MIYAKAWA Takuya，HACHIMURA Satoshi
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18H02152
[Presentation] Intestinal Regulatory T Cell Induction by β-Elemene Alleviates the Formation of Fat Tissue-Related Inflammation.2020
- Author(s)
  Yingyu Zhou, Tomohiro Takano, Yimei Wang, Xuyang Li, Rong Wang, Haruyo Nakajima-Adachi, Masaru Tanokura, Takuya Miyakawa, Satoshi Hachimura
- Organizer
  9th International Conference on Nutrition and Food Sciences (ICNFS 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02152
[Presentation] 腸間膜リンパ節樹状細胞およびT細胞のレチノイン酸に関わる応答の加齢による変化2017
- Author(s)
  高野智弘, 上滝隆太郎, 宮川拓也, 朴知賢, 塩河亜弥, 好田正, 足立 (中嶋) はるよ, 田之倉優, 八村敏志
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギーの経皮免疫療法モデルにおける作用機序の解析2017
- Author(s)
  森永真実子,平出恵利華,土井雅津代,北村紀子,神沼修,廣井隆親,足立（中嶋）はるよ,八村敏志
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都）
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 腸間膜リンパ節樹状細胞のRALDH活性および腸管指向性ホーミングレセプター誘導能の加齢による変化2016
- Author(s)
  高野智弘、上滝隆太郎、宮川拓也、朴知賢、塩河亜弥、好田正、足立 (中嶋) はるよ、田之倉優、八村敏志
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 経口免疫寛容において誘導されるCD62Lhigh/intCD44intおよびCD62LlowCD44high T細胞の遺伝子発現・機能解析2016
- Author(s)
  芝原恭子、門岡桂史、片倉喜範、田邊康祐、塩河亜弥、村上仁、細野朗、上野川修一、足立(中嶋) はるよ、八村敏志
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギーの経皮免疫療法モデルの解析2016
- Author(s)
  森永真実子,平出恵利華,足立(中嶋) はるよ,八村敏志
- Organizer
  日本食品免疫学会2016年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2016-11-09
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギー性腸炎モデルを用いた評価系の構築2016
- Author(s)
  足立（中嶋）はるよ、平出恵利華、八村敏志
- Organizer
  第89回　日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギー性皮膚炎モデルにおけるCD4+T細胞応答の解析2016
- Author(s)
  平出恵利華、足立（中嶋）はるよ、戸村道夫、北村紀子、上滝隆太郎、神沼修、廣井隆親、八村敏志
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 腸間膜リンパ節樹状細胞におけるRALDH2発現のサブセット間比較および加齢による影響2015
- Author(s)
  高野智弘、上滝隆太郎、宮川拓也、好田正、牧野聖也、狩野宏、足立（中嶋）はるよ、田之倉優、八村敏志
- Organizer
  日本食品免疫学会2015年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギー性皮膚炎モデルにおける免疫細胞の移動の解析2015
- Author(s)
  平出恵利華、足立（中嶋）はるよ、戸村道夫、八村敏志
- Organizer
  日本食品免疫学会2015年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] Functional differences in two different antigen specific T cell subsets induced in oral tolerance2015
- Author(s)
  SHIBAHARA Kyoko, SHIOKAWA Aya, HOSONO Akira, NAKAJIMA-ADACHI Haruyo, HACHIMURA Satoshi
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 腸間膜リンパ節樹状細胞におけるRALDH2発現の低下と乳酸菌による調節2014
- Author(s)
  高野智弘、宮川拓也、上滝隆太郎、牧野聖也、狩野宏、浅見幸夫、足立（中嶋）はるよ、田之倉優、八村敏志
- Organizer
  日本食品免疫学会2014年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 経口免疫寛容においてCD62LとCD44の発現で規定されるT細胞群の分布と挙動解析2014
- Author(s)
  芝原恭子、門岡桂史、片倉喜範、細野朗、上野川修一、足立（中嶋）はるよ、八村敏志
- Organizer
  日本食品免疫学会2014年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26292065
[Presentation] 食物アレルギー性皮膚炎モデルにおけるCD4+T細胞の解析2014
- Author(s)
  平出恵利華、足立（中嶋）はるよ、上滝隆太郎、八村敏志
- Organizer
  日本食品免疫学会2014年度大会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26292065

1. HACHIMURA SATOSHI (40238019)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. HOSONO Akira (70328706)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. TAKAHASHI Yoshimasa (60311403)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. NAKAYAMA Jiro (40217930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮川拓也 (50596559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 角田茂 (80345032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小川哲弘 (40323480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 後藤康之 (50553434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田川陽一 (70262079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAHASHI Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 清野宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Adachi Haruyo 足立 はるよ (中嶋 はるよ)

中嶋はるよ

Nakajima-Adachi Haruyo 足立 はるよ

ADACHI Haruyo 足立 はるよ

NAKAJIMA Haruyo 足立 はるよ

Research Projects

Research Products

Co-Researchers

Functional analysis of tissue-resident memory regulatory T cells of the intestine in bone loss associated with gastrointestinal allergy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel technology for regulating biological functions via colonization-improved E. coli: in vivo trial using disease model animal

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of function of pathogenic-memory T cells on bone loss combined with food allergic enteropahyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of chronic inflammation in aging and adipose tissues via the intestinal immune system by food

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Immunomodulation by foods based on elucidation of novel interactions of intestinal immune cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of recognition and response of intestinal immune cells to microbes in relation to development of immunomodulating functional foods

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>Lactobacillus plantarum</i> OLL2712 induces IL-10 production by intestinal dendritic cells2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Induction of Oral Tolerance by Pepsin-Digested Gliadin Retaining T Cell Reactivity in a Mouse Model of Wheat Allergy.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intestinal regulatory T cell induction by β-elemene alleviates the formation of fat tissue-related inflammation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical role of intestinal interleukin-4 modulating regulatory T Cells for desensitization, tolerance, and inflammation of food allergy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Attenuation of migration properties of CD4+ T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid and RALDH expression compared to young mice.2014

Author(s)

Journal Title

Data Source

[Journal Article] Oral Administration of Lactobacillus plantarum Strain AYA Enhances IgA Secretion and Provides Survival Protection against Influenza Virus Infection in Mice.2014

Author(s)

Journal Title

Data Source

Adachi Haruyo 足立はるよ (中嶋はるよ)

Nakajima-Adachi Haruyo 足立はるよ

ADACHI Haruyo 足立はるよ

NAKAJIMA Haruyo 足立はるよ