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YAMAMOTO NOBUYUKI  山本 暢之

… Alternative Names

Yamamoto Nobuyuki  山本 暢之

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Researcher Number 20596043
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1006-7394
Affiliation (Current) 2025: 神戸大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2024: 神戸大学, 医学研究科, 准教授
2022 – 2023: 神戸大学, 医学部附属病院, 講師
2021: 神戸大学, 医学部附属病院, 助教
2019: 神戸大学, 医学部附属病院, 特定助教
2017 – 2018: 神戸大学, 医学研究科, 医学研究員
2015 – 2016: 神戸大学, 医学部附属病院, 助教
2014: 神戸大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords
Principal Investigator
がん幹細胞 / Rabファミリー低分子量G蛋白質 / DENNドメイン蛋白質 / 細胞内小胞輸送 / 神経芽腫 / Rab9B / DENND2A / 低分子量G蛋白質
Except Principal Investigator
神経芽腫 / 細胞老化随伴分泌現象 … More / 治療誘発細胞老化 / 間葉系幹細胞 / セノモルフィック剤 / セノリティック剤 / がん微小環境 / 微小残存病変 / 高リスク神経芽腫 / Rab / 腫瘍随伴線維芽細胞 / がん幹細胞 / 神経芽腫細胞 Less
  • Research Projects

    (5 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (7 People)
  •  治療誘発老化細胞を標的とした神経芽腫の新規治療法に関する研究

    • Principal Investigator
      西村 範行
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  Role of mesenchymal stem cells in the regulation of neuroblastoma microenvironment

    • Principal Investigator
      Nishimura Noriyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  Role of Rab family small G proteins in the regulation of neuroblastoma microenvironment

    • Principal Investigator
      Nishimura Noriyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Role of DENND2A for development of neuroblastomaPrincipal Investigator

    • Principal Investigator
      YAMAMOTO NOBUYUKI
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Role of DENN domain proteins in the development of neuroblastoma cancer stem cells.Principal Investigator

    • Principal Investigator
      Yamamoto Nobuyuki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

  • [Journal Article] Higher levels of minimal residual disease in peripheral blood than bone marrow before 1st and 2nd relapse/regrowth in a patient with high-risk neuroblastoma: A case report.2023

    • Author(s)
      Inoue S, Win KHN, Mon CY, Fujikawa T, Hyodo S, Uemura S, Ishida T, Mori T, Hasegawa D, Kosaka Y, Nishimura A, Nakatani N, Nino N, Tamura A, Yamamoto N, Noze K, and Nishimura N.
    • Journal Title

      Oncol Let

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07750
  • [Journal Article] Minimal residual disease detected by droplet digital PCR in peripheral blood stem cell grafts has a prognostic impact on high-risk neuroblastoma patients2022

    • Author(s)
      Nino Nanako、Ishida Toshiaki、Nakatani Naoko、Lin Kyaw San、Win Kaung Htet Nay、Mon Cho Yee、Nishimura Akihiro、Inoue Shotaro、Tamura Akihiro、Yamamoto Nobuyuki、Uemura Suguru、Saito Atsuro、Mori Takeshi、Hasegawa Daiichiro、Kosaka Yoshiyuki、Nozu Kandai、Nishimura Noriyuki
    • Journal Title

      Heliyon

      Volume: 8 Issue: 10 Pages: e10978-e10978

    • DOI

      10.1016/j.heliyon.2022.e10978

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07750
  • [Journal Article] Minimal residual disease in high-risk neuroblastoma shows a dynamic and disease burden-dependent correlation between bone marrow and peripheral blood2021

    • Author(s)
      Kyaw San Lin
    • Journal Title

      Transl Oncol

      Volume: 14 Issue: 8 Pages: 101019-101019

    • DOI

      10.1016/j.tranon.2021.101019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17331, KAKENHI-PROJECT-21K07750
  • [Journal Article] Limited correlation between tumor markers and minimal residual disease detected by seven neuroblastoma-associated mRNAs in high-risk neuroblastoma patients2021

    • Author(s)
      Suguru Uemura, Kyaw San Lin, Khin Kyae Mon Thwin, Naoko Nakatani, Toshiaki Ishida, Nobuyuki Yamamoto, Akihiro Tamura, Atsuro Saito, Takeshi Mori, Daiichiro Hasegawa, Yoshiyuki Kosaka, Nanako Nino, China Nagano, Satoru Takafuji, Kazumoto Iijima, Noriyuki Nishimura
    • Journal Title

      Mol Clin Oncol

      Volume: 15 Issue: 1 Pages: 137-137

    • DOI

      10.3892/mco.2021.2299

    • NAID

      120007098982

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17331, KAKENHI-PROJECT-19K17361, KAKENHI-PROJECT-21K07750
  • [Journal Article] Level of Seven Neuroblastoma-Associated mRNAs Detected by Droplet Digital PCR Is Associated With Tumor Relapse/Regrowth of High-Risk Neuroblastoma Patients2020

    • Author(s)
      Khin K M Thwin
    • Journal Title

      J Mol Diagn .

      Volume: 22 Issue: 2 Pages: 236-246

    • DOI

      10.1016/j.jmoldx.2019.10.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17331, KAKENHI-PROJECT-17K10110
  • [Journal Article] Dynamics of Minimal Residual Disease in Neuroblastoma Patients2019

    • Author(s)
      Suguru Uemura
    • Journal Title

      Front Oncol

      Volume: 9 Pages: 455-455

    • DOI

      10.3389/fonc.2019.00455

    • NAID

      120006645720

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17331, KAKENHI-PROJECT-17K10110
  • [Journal Article] Early detection of tumor relapse/re-growth by consecutive minimal residual disease monitoring in high-risk neuroblastoma patients.2016

    • Author(s)
      Hirase S, Saitoh A, Hartomo TB, Kozaki A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Yamamoto N, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
    • Journal Title

      Oncol Let

      Volume: 12 Issue: 2 Pages: 1119-1123

    • DOI

      10.3892/ol.2016.4682

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-16K19644
  • [Journal Article] Differential expression of minimal residual disease markers in peripheral blood and bone marrow samples from high-risk neuroblastoma patients.2015

    • Author(s)
      Yamamoto N, Kozaki A, Hartomo TB, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Hirase S, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
    • Journal Title

      Oncol Let

      Volume: 10 Issue: 5 Pages: 3228-3232

    • DOI

      10.3892/ol.2015.3710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-26860801, KAKENHI-PROJECT-26860802
  • [Journal Article] Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma.2015

    • Author(s)
      Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hasegawa D, Kosaka Y, Matsuo M, Hayakawa A, Takeshima Y, Iijima K, Nishio H, and Nishimura N.
    • Journal Title

      Int J Oncol

      Volume: 46 Issue: 3 Pages: 1089-1098

    • DOI

      10.3892/ijo.2014.2801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-26860801, KAKENHI-PROJECT-26860802
  • [Presentation] Disease burden-dependent correlation of neuroblastoma minimal residual disease between bone marrow and peripheral blood.2021

    • Author(s)
      Lin KS, Uemura S, Thwin KK, Ishida T, Yamamoto N, Nishimura N.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07750
  • [Presentation] 高リスク神経芽腫における微小残存病変(MRD)と腫瘍マーカーの相関に関する臨床的検討.2021

    • Author(s)
      植村優, Lin KS, Thwin KK, 中谷尚子,石田敏章, 山本暢之, 田村彰広, 齋藤敦郎, 森健, 長谷川大一郎, 小阪嘉之, 二野菜々子, 長野智那, 高藤哲, 飯島一誠, 西村範行.
    • Organizer
      第124回日本小児科学会
    • Data Source
      KAKENHI-PROJECT-21K07750
  • [Presentation] Level of seven neuroblastoma-associated mRNAs analyzed by droplet digital PCR is correlated between bone marrow and peripheral blood in high-risk neuroblastoma.2019

    • Author(s)
      Uemura S, Ishida T, Thwin KK, Lin KS, Yamamoto N, Tamura A, Kishimoto K, Mori T, Hasegawa D, Kosaka Y, Nino N, Takafuji S, Iijima K, Nishimura N.
    • Organizer
      第61回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Expression of seven neuroblastoma-associated mRNAs is correlated between bone marrow and peripheral blood in high-risk neuroblastoma patients2019

    • Author(s)
      Thwin KK, Lin KS, Ishida T, Uemura S, Yamamoto N, Nishimura N.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Elevated minimal residual disease marker expression in peripheral blood of three high-risk neuroblastoma cases.2018

    • Author(s)
      Thwin KK, Ishida T, Uemura S, Yamamoto N, Tamura A, Kozaki A, Saito A, Kishimoto K, Hasegawa D, Kosaka Y, Nino N, Takafuji S, Mori T, Iijima K, Nishimura N.
    • Organizer
      Advances in Neuroblastoma Research Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Quantitation of minimal residual disease by droplet digital PCR in high-risk neuroblastoma patients.2018

    • Author(s)
      Nishimura N, Ishida T, Thwin KK, Uemura S, Yamamoto N, Tamura A, Nino N, Kozaki A, Saito A, Kishimoto K, Hasegawa D, Kosaka Y, Takafuji S, Mori T, Iijima K.
    • Organizer
      第60回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Detection of minimal residual disease in high-risk neuroblastoma patients by digital PCR.2018

    • Author(s)
      Nishimura N, Ishida T, Uemura S, Yamamoto N, Hasegawa D.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Expression profiles of seven minimal residual disease markers in bone marrow and peripheral blood of patients with high-risk neuroblastoma.2018

    • Author(s)
      Thwin KK, Ishida T, Uemura S, Yamamoto N, Tamura A, Kozaki A, Saito A, Kishimoto K, Hasegawa D, Kosaka Y, Nino N, Takafuji S, Mori T, Iijima K, Nishimura N.
    • Organizer
      The 50th Congress of the International Society of Pediatric Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] Involvement of DENND2A and Rab9B in the progression of neuroblastoma2017

    • Author(s)
      NOBUYUKI YAMAMOTO
    • Organizer
      3rd Asia-Pacific International Symposium of Neuroblastoma
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19644
  • [Presentation] Involvement of DENND2A and Rab9B in the progression of neuroblastoma.2017

    • Author(s)
      Yamamoto N, Thwin KK, Takafuji S, Uemura S, Nino N, Mori T, Ishida T, Hasegawa D, Kosaka Y, Iijima K, and Nishimura N.
    • Organizer
      3rd Asia-Pacific International Symposium of Neuroblastoma
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10110
  • [Presentation] DENN domain protein DENND2A regulates the progression of neuroblastoma2016

    • Author(s)
      Nobuyuki Yamamoto, Khin Kyaemon Thwin, Jun-ya Fujimura, Keita Nakanishi, Takeshi Mori, Akira Hayakawa, Hisahide Nishio, Masafumi Matsuo, Daiichiro Hasegawa, Keiichiro Kawasaki, Yoshiyuki Kosaka, Kazumoto Iijima, and Noriyuki Nishimura
    • Organizer
      Advance in Neuroblastoma Research Conference 2016
    • Place of Presentation
      Cairns Convention Centre, Cairns, Australia
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19644
  • [Presentation] 神経芽腫患者の微小残存病変モニタリング2016

    • Author(s)
      西村範行, Khin Kyaemon Thwin, 山本暢之, 森健, 早川晶, 長谷川大一郎, 川崎圭一郎, 小阪嘉之, 西尾久英, 飯島一誠.
    • Organizer
      第119回日本小児科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-16K19644
  • [Presentation] Rab6B mediates the progression of neuroblastoma through the interaction with MTMR5.2016

    • Author(s)
      Nishimura N, Pham TVH, Thwin KK, Yamamoto N, Mori T, Hayakawa A, Nishio H, Matsuo M, Hasegawa D, Kawasaki K, Kosaka Y, and Iijima K.
    • Organizer
      Advances in Neuroblastoma Research Conference 2016
    • Place of Presentation
      Cairns Convention Centre, Cairns, Australia
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19644
  • [Presentation] DENN domain protein DENND2A regulates the progression of neuroblastoma2016

    • Author(s)
      Nobuyuki Yamamoto, Khin Kyaemon Thwin, Jun-ya Fujimura, Keita Nakanishi, Takeshi Mori, Akira Hayakawa, Hisahide Nishio, Masafumi Matsuo, Dai-ichiro Hasegawa, Kei-ichiro Kawasaki, Yoshiyuki Kosaka, Kazumoto Iijima, Noriyuki Nishimura
    • Organizer
      Advance in Neuroblastoma Research Conference
    • Place of Presentation
      Cairns Convention Centre, Cairns, Australia
    • Year and Date
      2016-06-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Differential expression of minimal residual disease markers in peripheral blood and bone marrow samples from high-risk neuroblastoma patients.2015

    • Author(s)
      Uemura S, Yamamoto N, Kozaki A, Nino N, Takafuji S, Yokoi T, Saito A, Ishida T, Hasegawa D, Kawasaki K, Kosaka Y, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
    • Organizer
      第57回日本小児血液がん学会
    • Place of Presentation
      甲府富士屋ホテル
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] 神経芽腫の発症・進展におけるRab6BとRab28の役割.2015

    • Author(s)
      西村範行, 山本暢之, 長谷川大一郎.
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Involvement of DENN domain protein DENND2A in the progression of neuroblastoma2015

    • Author(s)
      Nobuyuki Yamamoto, Daiichiro Hasegawa, and Noriyuki Nishimura
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Neuroblastoma minimal residual disease markers are differentially expressed in peripheral blood and bone marrow samples.2015

    • Author(s)
      Uemura S, Yamamoto N, Kozaki A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
    • Organizer
      11th Asian Society for Pediatric Research
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2015-04-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] DENN domain protein DENND2A mediates the progression of neuroblastoma2015

    • Author(s)
      Yamamoto N, Horinouchi T, Fujimura J, Mori T, Hayakawa A, Hasegawa D, Kosaka Y, Nishio H, Iijima K, and Nishimura N.
    • Organizer
      第57回日本小児血液がん学会
    • Place of Presentation
      甲府富士屋ホテル
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Aldehyde dehydrogenase ALDH1A2 regulates cancer stem cell properties in neuroblastoma.

    • Author(s)
      Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Iijima K, Nishio H.
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Aldehyde dehydrogenase 1A2 expression correlates with cancer stem cell properties in neuroblastoma

    • Author(s)
      Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, and Nishio H.
    • Organizer
      Advances in Neuroblastoma Research Conference 2014
    • Place of Presentation
      Cologne, Germany
    • Year and Date
      2014-05-13 – 2014-05-16
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] Induction of ALDH1A2 expression is critical for cancer stem cell properties in neuroblastoma.

    • Author(s)
      Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, and Nishio H.
    • Organizer
      AACR Annual Meeting 2014
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26860801
  • [Presentation] 神経芽腫がん幹細胞の発生・分化における細胞内小胞輸送の制御因子Rab6Bの役割.

    • Author(s)
      西村範行, Thi Van Huyen Pham, Tri Budi Hartomo, 山本暢之, 平瀬敏志, 早川晶, 矢内友子, 長谷川大一郎, 川崎圭一郎, 小阪嘉之, 松尾雅文, 飯島一誠, 西尾久英.
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-26860801
  • 1.  Nishimura Noriyuki (00322719)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 27 results
  • 2.  Kosaka Yoshiyuki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  Hayakawa Akira (40379376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 4.  Yanai Tomoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  Mori Takeshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  西尾 久英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 7.  植村 優
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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