Takahashi Azusa 高橋梓

… Alternative Names

Takahashi-Nakaguchi Azusa 高橋梓

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Researcher Number	20607949
Other IDs
Affiliation (Current)	2025: 千葉大学, 真菌医学研究センター, 技術職員
Affiliation (based on the past Project Information) *help	2024: 千葉大学, 真菌医学研究センター, 技術職員 2014 – 2022: 千葉大学, 真菌医学研究センター, 技術職員 2013: 千葉大学, 真菌医学研究センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) Except Principal Investigator Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator 強酸耐性 / 酸耐性 / Candida glabrata / 病原酵母 / カンジダ症 / candida / アスペルギルス / A.fumigatus / Aspergillus / マイコウイルス … More Except Principal Investigator … More 真菌症 / 必須遺伝子 / 薬剤標的 / 抗真菌薬 / Candida Less

Development of antifungal drugs that eliminate damage to infected hosts due to fungal cell death
- Principal Investigator
  
  知花博治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Chiba University
病原酵母による「トロイの木馬」腸管突破機構Principal Investigator
- Principal Investigator
  
  高橋梓
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Chiba University
Functional analysis of a novel gene cluster responsible for strong acid resistance in the causative agent of invasive candidiasis.Principal Investigator
- Principal Investigator
  
  Takahashi Azusa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Chiba University
Acid-resistance systems in Candida glabrataPrincipal Investigator
- Principal Investigator
  
  Takahashi-Nakaguchi Azusa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Chiba University
A novel dsRNA mycovirus reduces pathogenicity of Aspergillus fumigatus in a mouse infection model.Principal Investigator
- Principal Investigator
  
  Takahashi-Nakaguchi Azusa
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility2023
- Author(s)
  Okamoto Michiyo、Nakano Keiko、Takahashi-Nakaguchi Azusa、Sasamoto Kaname、Yamaguchi Masashi、Teixeira Miguel Cacho、Chibana Hiroji
- Journal Title
  
  Journal of Fungi
  
  Volume: 9 Issue: 2 Pages: 240-240
- DOI
  10.3390/jof9020240
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07475, KAKENHI-PROJECT-20K07494
[Journal Article] Ultrastructural examination of mouse kidney glomerular capillary loop by sandwich freezing and freeze-substitution2022
- Author(s)
  Yamaguchi Masashi、Takahashi-Nakaguchi Azusa、Uematsu Katsuyuki、Yamada Hiroyuki、Sato-Okamoto Michiyo、Chibana Hiroji
- Journal Title
  
  Microscopy
  
  Volume: 71 Issue: 5 Pages: 289-296
- DOI
  10.1093/jmicro/dfac031
- Data Source
  KAKENHI-PROJECT-20K07494
[Journal Article] Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata2022
- Author(s)
  Okamoto Michiyo、Takahashi-Nakaguchi Azusa、Tejima Kengo、Sasamoto Kaname、Yamaguchi Masashi、Aoyama Toshihiro、Nagi Minoru、Tanabe Kohichi、Miyazaki Yoshitsugu、Nakayama Hironobu、Sasakawa Chihiro、Kajiwara Susumu、Brown Alistair J. P.、Teixeira Miguel C.、Chibana Hiroji
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 1-19
- DOI
  10.3389/fcell.2022.820675
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40149, KAKENHI-PROJECT-20K07475, KAKENHI-PROJECT-17K15696, KAKENHI-PROJECT-20K07494
[Journal Article] Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants2022
- Author(s)
  Pais Pedro、Galocha M?nica、Takahashi-Nakaguchi Azusa、Chibana Hiroji、Teixeira Miguel C.
- Journal Title
  
  Microbial Cell
  
  Volume: 9 Issue: 11 Pages: 174-189
- DOI
  10.15698/mic2022.11.786
- Data Source
  KAKENHI-PROJECT-20K07494
[Journal Article] From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view2021
- Author(s)
  Cavalheiro Mafalda、Pereira Diana、Formosa-Dague C?cile、Leit?o Carolina、Pais Pedro、Ndlovu Easter、Viana Romeu、Pimenta Andreia I.、Santos Rui、Takahashi-Nakaguchi Azusa、Okamoto Michiyo、Ola Mihaela、Chibana Hiroji、Fialho Ars?nio M.、Butler Geraldine、Dague Etienne、Teixeira Miguel C.
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 02412-7
- DOI
  10.1038/s42003-021-02412-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40149, KAKENHI-PROJECT-20K07475, KAKENHI-PROJECT-20K07494
[Journal Article] Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From Aspergillus fumigatus: Reduced Fungal Virulence in a Mouse Infection Model2021
- Author(s)
  Takahashi-Nakaguchi A, Shishido E, Yahara M, Urayama M, Ninomiya A, Chiba Y, Sakai K, Hagiwara D, Chibana H, Moriyama H, Gonoi T
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 11 Pages: 1-17
- DOI
  10.3389/fmicb.2020.607795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05946, KAKENHI-PROJECT-20K07494, KAKENHI-PROJECT-20KK0137
[Journal Article] Rapid Freezing using Sandwich Freezing Device for Good Ultrastructural Preservation of Biological Specimens in Electron Microscopy2021
- Author(s)
  Yamaguchi Masashi、Takahashi-Nakaguchi Azusa、Uematsu Katsuyuki、Taguchi Masaki、Sato-Okamoto Michiyo、Chibana Hiroji
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 173 Issue: 173 Pages: 62431-62431
- DOI
  10.3791/62431
- Data Source
  KAKENHI-PROJECT-20K07494
[Journal Article] Role of CgTpo4 in Polyamine and Antimicrobial Peptide Resistance: Determining Virulence in Candida glabrata2021
- Author(s)
  Cavalheiro Mafalda、Romo Daniela、Santos Rui、Mil-Homens Dalila、Pais Pedro、Costa Catarina、Galocha Monica、Pereira Diana、Takahashi-Nakaguchi Azusa、Chibana Hiroji、Fialho Arsenio M.、Teixeira Miguel C.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1376-1376
- DOI
  10.3390/ijms22031376
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02653, KAKENHI-PROJECT-20K07494
[Journal Article] Analysis of an intrinsic mycovirus associated with reduced virulence of the human pathogenic fungus Aspergillus fumigatus.2020
- Author(s)
  Takahashi-Nakaguchi A., Shishido E., Yahara M., Urayama SI., Sakai K., Chibana H., Kamei K., Moriyama H., Gonoi T.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 10 Pages: 1-22
- DOI
  10.3389/fmicb.2019.03045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05946, KAKENHI-PROJECT-17K15683, KAKENHI-PROJECT-20K07494
[Journal Article] Screening the Drug:H+ Antiporter Family for a Role in Biofilm Formation in Candida glabrata2020
- Author(s)
  Santos Rui、Cavalheiro Mafalda、Costa Catarina、Takahashi-Nakaguchi Azusa、Okamoto Michiyo、Chibana Hiroji、Teixeira Miguel C.
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 10 Pages: 00029-00029
- DOI
  10.3389/fcimb.2020.00029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07494, KAKENHI-PROJECT-18J40149
[Journal Article] Sandwich freezing device for rapid freezing of viruses, bacteria, yeast, cultured cells and animal and human tissues in electron microscopy2020
- Author(s)
  Yamaguchi Masashi、Taguchi Masaki、Uematsu Katsuyuki、Takahashi-Nakaguchi Azusa、Sato-Okamoto Michiyo、Chibana Hiroji
- Journal Title
  
  Microscopy
  
  Volume: 70 Issue: 2 Pages: 215-223
- DOI
  10.1093/jmicro/dfaa049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07475, KAKENHI-PROJECT-18J40149, KAKENHI-PROJECT-20K07494
[Journal Article] Aspergillus fumigatus adhesion factors in dormant conidia revealed through comparative phenotypic and transcriptomic analyses2018
- Author(s)
  Takahashi-Nakaguchi A, Sakai K, Takahashi H, Hagiwara D, Toyotome T, Chibana H, Watanabe A, Yaguchi T, Yamaguchi M, Kamei K, Gonoi T
- Journal Title
  
  Cell Microbiol
  
  Volume: 20 Issue: 3 Pages: e12802-e12802
- DOI
  10.1111/cmi.12802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18672, KAKENHI-PROJECT-18K07103, KAKENHI-PROJECT-17K15683
[Journal Article] Discrepancy between Hepatitis C Virus Genotypes and NS4-Based Serotypes: Association with Their Subgenomic Sequences.2017
- Author(s)
  Nan Nwe Win, Shingo Nakamoto, Tatsuo Kanda, Hiroki Takahashi, Azusa Takahashi-Nakaguchi, Shin Yasui, Masato Nakamura, Shuang Wu, Fumio Imazeki, Shigeru Mikami, Osamu Yokosuka, Tohru Gonoi, Hiroshi Shirasawa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18(1) Issue: 1 Pages: 172-172
- DOI
  10.3390/ijms18010172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860314, KAKENHI-PROJECT-26860491
[Journal Article] KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata.2016
- Author(s)
  Yutaka Tanaka, Masato Sasaki, Fumie Ito, Toshio Aoyama, Michiyo Sato-Okamoto, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Nobuyuki Shibata
- Journal Title
  
  PLoS ONE
  
  Volume: 11(8) Issue: 8 Pages: e0161371-e0161371
- DOI
  10.1371/journal.pone.0161371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860314
[Journal Article] The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata.2016
- Author(s)
  Ruben T Bernardo, Diana V Cunha, Can Wang, Leonel Pereira, Sand 243;nia Silva, Sara B Salazar, Markus S Schr246;der, Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Toshihiro Aoyama, Isabel S225;-Correia, Joana Azeredo, Geraldine Butler, Nuno Pereira Mira
- Journal Title
  
  Genomes Genetics
  
  Volume: 7(1) Issue: 1 Pages: 1-18
- DOI
  10.1534/g3.116.034660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860314, KAKENHI-PROJECT-15K19090
[Journal Article] Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.2015
- Author(s)
  Nakano T1, Takahashi-Nakaguchi A, Yamamoto M, Watanabe M.
- Journal Title
  
  Curr Top Microbiol Immunol.
  
  Volume: 384 Pages: 127-49
- DOI
  10.1007/82_2014_416
- ISBN
  9783319107707, 9783319107714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860314
[Journal Article] Genome sequence comparison of Aspergillus fumigatus strains isolated from patients with pulmonary aspergilloma and chronic necrotizing pulmonary aspergillosis2015
- Author(s)
  Takahashi-Nakaguchi A, Yasunori Muraosa Y, Hagiwara D, Sakai K,Toyotome T, Watanabe A, Kawamoto S, Kamei K, Gonoi T, Takahashi H
- Journal Title
  
  Medical Mycology
  
  Volume: 53 Issue: 4 Pages: 353-360
- DOI
  10.1093/mmy/myv003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659479, KAKENHI-PROJECT-25860314, KAKENHI-PROJECT-25305012
[Journal Article] Demonstration of cytotoxicity against wasps by pierisin-1: a possible defense factor in the cabbage white butterfly.2013
- Author(s)
  Takahashi-Nakaguchi A, Matsumoto Y, Yamamoto M, Iwabuchi K, Totsuka Y, Sugimura T, Wakabayashi K.
- Journal Title
  
  PLoS One.
  
  Volume: 23 Issue: 4 Pages: e60539-e60539
- DOI
  10.1371/journal.pone.0060539
- Data Source
  KAKENHI-PROJECT-25860314
[Presentation] Genome-wide functional analysis of pathogenetic yeast, Candida glabrata in dissemination from the murine gastrointestinal tract2023
- Author(s)
  Azusa Takahashi-Nakaguchi, Kaname Sasamoto, Keiko Nakano, Michiyo Sato-Okamoto, and Hiroji Chibana
- Organizer
  The 9th Global Network Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07494
[Presentation] 真菌の病原性を抑制するマイコウイルス2021
- Author(s)
  高橋梓
- Organizer
  細菌学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07494
[Presentation] Candida glabrataにおける強酸耐性機構2019
- Author(s)
  高橋梓，佐藤美智代，知花博冶
- Organizer
  日本細菌学会
- Data Source
  KAKENHI-PROJECT-17K15683
[Presentation] Candida glabrataにおける病原性関連遺伝子の網羅的解析法の開発2019
- Author(s)
  高橋梓，笹本　要、佐藤美智代，知花博冶
- Organizer
  日本医真菌学会
- Data Source
  KAKENHI-PROJECT-17K15683
[Presentation] 病原真菌Aspergillus fumigatusを弱毒化するマイコウイルスの遺伝子発現解析2015
- Author(s)
  宍戸絵里香，高橋梓，森山裕充，五ノ井透
- Organizer
  糸状菌分子生物学会
- Place of Presentation
  ルミエール府中（東京都、府中市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25860314
[Presentation] Identification of mycovirus genes associated with reduced pathogenicity of Aspergillus fumigatus.2015
- Author(s)
  Erika Shishido, Azusa Takahashi-Nakaguchi, Akikazu Ando, Hiromitsu Moriyama, Tohru Gonoi
- Organizer
  International Society for Human and Animal Mycology.
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860314
[Presentation] 肺アスペルギルス症の病原性を抑制するマイコウイルス2014
- Author(s)
  高橋梓、八原美沙、五ノ井透
- Organizer
  真菌症フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860314
[Presentation] 肺アスペルギルス症の病原性を抑制するマイコウイルス2014
- Author(s)
  高橋梓、八原美沙、五ノ井透
- Organizer
  日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860314
[Presentation] A novel dsRNA mycovirus reduces pathogenicity of Aspergillus fumigatus in a mouse infection model.
- Author(s)
  Azusa Takahashi-Nakaguchi, Misa Yahara, Erika Shishido, Hiromitsu Moriyama, Tohru Gonoi
- Organizer
  International Union of Microbiological Societies (IUMS) Congresses
- Place of Presentation
  Montrial, Canada
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25860314

1. 知花博治 (30333488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 佐藤美智代 (70525386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 三室仁美 (80396887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. URAYAMA Syun-ishi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAHARA Misa

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. SHISHIDO Erika

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. HIBIYA Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORIYAMA Hiromitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. HAGIWARA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 五ノ井透

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Azusa 高橋 梓

Takahashi-Nakaguchi Azusa 高橋 梓

Research Projects

Research Products

Co-Researchers

Development of antifungal drugs that eliminate damage to infected hosts due to fungal cell death

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

病原酵母による「トロイの木馬」腸管突破機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of a novel gene cluster responsible for strong acid resistance in the causative agent of invasive candidiasis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Acid-resistance systems in Candida glabrataPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel dsRNA mycovirus reduces pathogenicity of Aspergillus fumigatus in a mouse infection model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ultrastructural examination of mouse kidney glomerular capillary loop by sandwich freezing and freeze-substitution2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From Aspergillus fumigatus: Reduced Fungal Virulence in a Mouse Infection Model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid Freezing using Sandwich Freezing Device for Good Ultrastructural Preservation of Biological Specimens in Electron Microscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of CgTpo4 in Polyamine and Antimicrobial Peptide Resistance: Determining Virulence in Candida glabrata2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of an intrinsic mycovirus associated with reduced virulence of the human pathogenic fungus Aspergillus fumigatus.2020

Author(s)

Journal Title

DOI

Data Source

Takahashi Azusa 高橋梓

Takahashi-Nakaguchi Azusa 高橋梓