Minegishi Yuriko 峯岸ゆり子

… Alternative Names

MINEGISHI Yuriko 峯岸ゆり子

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Researcher Number	20621832
Affiliation (Current)	2026: 国立障害者リハビリテーションセンター(研究所), 研究所感覚機能系障害研究部, 研究室長 2026: 公益財団法人がん研究会, がんプレシジョン医療研究センター分析生化学研究部, 客員研究員
Affiliation (based on the past Project Information) *help	2025: 公益財団法人がん研究会, がんプレシジョン医療研究センター分析生化学研究部, 特任研究員 2019 – 2024: 公益財団法人がん研究会, がんプレシジョン医療研究センタープロテオミクス解析グループ, 研究員 2017 – 2018: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 研究員 2014: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, 研究員 2012 – 2013: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 研究員
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 37030:Chemical biology-related Except Principal Investigator Basic Section 56060:Ophthalmology-related / Basic Section 43060:System genome science-related
Keywords	Principal Investigator がん免疫 / イムノペプチドミクス / 質量分析 / HLA / ネオ抗原 / イムノペプチド / 遺伝性網膜疾患 / E50K変異 / 神経変性疾患 / 正常眼圧緑内障 … More / Optineurin / オプチニューリン / 遺伝子変異 / プロテアソーム分解 / PROTAC / KRAS / 抗原提示 / プロテオゲノミクス / ラベルフリー定量 / 抗原ペプチド / ドライバー変異 / 網膜発生 / シャペロン / Leber先天性黒内障 / ノックインマウス / LCA / Leber先天黒内障 / CCT / モデル動物 / ゲノム編集 / CRISPR-Cas9 / 複合ヘテロ接合変異 / 網膜変性 / Leber先天性黒内障(LCA) / 分子細胞生物学 / 緑内障変異 / 遺伝性疾患 / E50K / 家族性緑内障 / 緑内障 … More Except Principal Investigator 免疫 / 老化 / EYS / 網膜色素変性 / 比較ゲノム解析 / 遺伝子デリバリー / ネオアンチゲン / トランスポゾン / 内在性ウイルス様配列 / 動物モデル / プロテオーム解析 / 分子シャペロン / 疾患モデル動物 / 視細胞 / 疾患モデルマウス / ゲノム編集 / マウス / 遺伝性網膜疾患 / レーベル黒内障 / 網膜 / シャペロニン / 病態解析 / モデルマウス Less

Development of a Research Platform for Functional Analysis of Proteins Derived from Endogenous Viral Elements in Mammalian Genomes
- Principal Investigator
  
  中川草
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Tokai University
Studies on involvement of aging- and immune-related molecules in onset and progression of retinitis pigmentosa using Eys-deficient zebrafish
- Principal Investigator
  
  世古裕子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Investigation of Target Protein Degradation and Its Effect on Enhancing Cancer-Specific Antigen Presentation by Quantitative Mass SpectrometryPrincipal Investigator
- Principal Investigator
  
  峯岸ゆり子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Japanese Foundation for Cancer Research
Generation and analysis of Leber congenital amaurosis mouse model with CCT2 point mutations
- Principal Investigator
  
  Okamoto Akiko
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Analysis of the rate-limiting factor for intracellular antigen processing of HLA class I antigen peptidesPrincipal Investigator
- Principal Investigator
  
  MINEGISHI Yuriko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Japanese Foundation for Cancer Research
Analysis of retinal function of LCA-causing CCT2 and the generation of mouse model and therapeuticsPrincipal Investigator
- Principal Investigator
  
  MINEGISHI Yuriko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Japanese Foundation for Cancer Research
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
OPTN-E50K変異性正常眼圧緑内障の遺伝子治療に向けた検討Principal Investigator
- Principal Investigator
  
  峯岸ゆり子
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Molecular analyses of glaucoma-associated mutations in OPTN gene and retinal blood flowPrincipal Investigator
- Principal Investigator
  
  MINEGISHI Yuriko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)

All 2025 2024 2023 2022 2021 2020 2018 2017 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 医用工学ハンドブック2022
- Author(s)
  峯岸ゆり子、植田幸嗣
- Total Pages
  475
- Publisher
  エヌ・ティー・エス
- ISBN
  4860437357
- Data Source
  KAKENHI-PROJECT-20K05759
[Book] Retina Medicine2014
- Author(s)
  峯岸ゆり子
- Total Pages
  111
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24791885
[Book] Retina Medicine Vol3. No2.2014
- Author(s)
  峯岸ゆり子
- Total Pages
  98
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-26861481
[Book] 日本人のヒット論文-本音で語る苦労話-第5回オプチニューリン E50K 変異による遺伝性緑内障発症の機序『Retina Medicine』(中澤徹編)2014
- Author(s)
  峯岸ゆり子
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24791885
[Book] 脳21　Vol.17 No.42014
- Author(s)
  峯岸ゆり子、　岩田岳
- Total Pages
  126
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-26861481
[Journal Article] The Japanese-German Symposium on the “Advancement and Application of Proteoform-Centric Proteomics”2025
- Author(s)
  Takemori, N., Kaulich, PT., Hahn, J., Schulter, H., Sugiyama, N., Tsumagari, K., Ishihama, Y., Fuchs, S., Iwasaki, M., Muller, FJ., Neususs;, C., Jeong, K., Kohlbacher, O., Shimizu, Y., Otsuka, O., Sato, H., Sasaki, K., Minegishi, Y., et al.
- Journal Title
  
  Proteomics
  
  Volume: - Issue: 19 Pages: 6-10
- DOI
  10.1002/pmic.202400394
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Journal Article] Emerging potential of immunopeptidomics by mass spectrometry in cancer immunotherapy2024
- Author(s)
  MINEGISHI, Y., Haga, Y., Ueda, K。
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 4 Pages: 1048-1059
- DOI
  10.1111/cas.16118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K04971, KAKENHI-PROJECT-23K21392, KAKENHI-PROJECT-23K05704
[Journal Article] Compound heterozygous mutations in a mouse model of Leber congenital amaurosis reveal the role of CCT2 in photoreceptor maintenance2024
- Author(s)
  Suga Akiko、Minegishi Yuriko、Yamamoto Megumi、Ueda Koji、Iwata Takeshi
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1 Pages: 676-676
- DOI
  10.1038/s42003-024-06384-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21392, KAKENHI-PROJECT-21K09689, KAKENHI-PROJECT-23K04971
[Journal Article] Current Status of Immunopeptidomics by Mass Spectrometry for Precision Cancer Immunotherapy2024
- Author(s)
  峯岸ゆり子、植田幸嗣
- Journal Title
  
  Proteome Letters
  
  Volume: 9 Issue: 1 Pages: 21-32
- DOI
  10.14889/jpros.9.1_21
- ISSN
  2432-2776
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21392, KAKENHI-PROJECT-23K04971
[Journal Article] Frontiers in mass spectrometry-based clinical proteomics for cancer diagnosis and treatment2023
- Author(s)
  Yoshimi Haga, Yuriko Minegishi, Koji Ueda
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 5 Pages: 1783-1791
- DOI
  10.1111/cas.15731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05759, KAKENHI-PROJECT-23K05704, KAKENHI-PROJECT-23K21392
[Journal Article] Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations2022
- Author(s)
  Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 831-831
- DOI
  10.1038/s42003-022-03807-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05759, KAKENHI-PROJECT-23K21392
[Journal Article] METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma2022
- Author(s)
  Pan Yang、Suga Akiko、Kimura Itaru、Kimura Chojiro、Minegishi Yuriko、Nakayama Mao、Yoshitake Kazutoshi、Iejima Daisuke、Minematsu Naoko、Yamamoto Megumi、Mabuchi Fumihiko、Takamoto Mitsuko、Shiga Yukihiro、Araie Makoto、Kashiwagi Kenji、Aihara Makoto、Nakazawa Toru、Iwata Takeshi
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 132 Issue: 21
- DOI
  10.1172/jci153589
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09689, KAKENHI-PROJECT-22K09787, KAKENHI-PROJECT-20K09786, KAKENHI-PROJECT-20K18366
[Journal Article] Function of ERAP2 (endoplasmic reticulum aminopeptidase 2) in cancer immunity2021
- Author(s)
  3.Hayashi, N., Ikeda, Y., Okamura, K., Tate, T., Nemoto, K., Nagayama, S., Minegishi, Y., Ueda, K., Kiyotani, K., Nakamura, Y. and Kei Kawana
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 148 Pages: 103410-103410
- DOI
  10.1016/j.jri.2021.103410
- Data Source
  KAKENHI-PROJECT-20K05759
[Journal Article] Differential immunopeptidome analysis revealed cancer specific amino acid usage of HLA class-I antigens and novel neoantigens of colorectal cancer2021
- Author(s)
  Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda
- Journal Title
  
  bioRxiv
  
  Volume: 10.1101 Pages: 439118-439118
- DOI
  10.1101/2021.04.09.439118
- Data Source
  KAKENHI-PROJECT-20K05759
[Journal Article] Mutation in the Zebrafish cct2 Gene Leads to Abnormalities of Cell Cycle and Cell Death in the Retina: A Model of CCT2-Related Leber Congenital Amaurosis2018
- Author(s)
  Minegishi Yuriko、Nakaya Naoki、Tomarev Stanislav I.
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 2 Pages: 995-1004
- DOI
  10.1167/iovs.17-22919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11472
[Journal Article] Enhanced Optineurin E50 K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.2013
- Author(s)
  Minegishi Y, Seki T, Yuasa S, Fukuda K, Iwata T, et al
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 22 Issue: 17 Pages: 3559-3367
- DOI
  10.1093/hmg/ddt210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J30002, KAKENHI-PUBLICLY-24117716, KAKENHI-PROJECT-24791885
[Presentation] 個別化がん免疫療法に向けた質量分析によるイムノペプチドミクス: 小さなペプチドが担う自己・非自己2025
- Author(s)
  峯岸ゆり子
- Organizer
  第228回Science-ome Anti-disciplinary Forum.
- Invited
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] An off-the-shelf multivalent vaccine containing cancer’s dark matter, DPV-001, combined with PD-1 +/- GITR in head & neck cancer: safety, efficacy, and immunodynamics from the phase 1 GITRVax trial.2024
- Author(s)
  Leidner, R.S., Paustian, C., Jensen, S.M., Moudgil, T., Koguchi, Y., Simons, N., Rajamanickam, V., Meng, R., Couey, M.A., Vu, Q., Taylor, M.H., Long, A., Staeck, A.J., Kaur, L., Jovanovic, T., Bernard, B., Christie, T., Iwamoto, N., Minegishi, Y., et al.
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] 個別化がん免疫療法に向けた包括的イムノペプチドミクス分析系の確立。2024
- Author(s)
  峯岸ゆり子、植田幸嗣
- Organizer
  timsTOF Ultra Live デモ＆ウェビナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] 微分型イオンモビリティを用いたがんドライバー遺伝子KRASの変異を有する内在性ネオ抗原配列種の同定2024
- Author(s)
  峯岸ゆり子、植田幸嗣
- Organizer
  日本プロテオーム学会2024年大会
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] イムノペプチドーム解析によるがん特異的HLA Class I提示抗原ペプチドの探索2024
- Author(s)
  峯岸ゆり子
- Organizer
  2024年がん関連三学会Rising Starネットワーキング
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Off-the-shelf dark matter immunotherapy in head & neck cancer: mechanistic insights and clinical efficacy.2024
- Author(s)
  Leidner, SR., Paustian, C., Jensen, MS, Moudgil, T., Simons, N., Koguchi, Y., Rajamanickam, V., Nijenhuis, DNLMD., Meng, R., Couey, M., Vu, Q., Taylor, HM., Kaur, L., Bernard, B., Christie, T., Iwamoto, N., Minegishi, Y., et al.
- Organizer
  The 39th annual Meeting of Society for Immunotherapy of Cancer(SITC) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Ion mobility-assisted immunopeptidomics for precision cancer immunotherapy.2024
- Author(s)
  Minegishi, Y.
- Organizer
  Advancement and Application of Methods for Proteoform-Centric Proteomics, Japanese-German Joint Symposium 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Dark immunopeptidome of head and neck squamous cell carcinoma in serial cell lines from a single patient during multimodality treatment time-course.2024
- Author(s)
  Meng, R., Moudgil, T., Iwamoto, N., Minegishi, Y., Koguchi, Y., Rajamanickam, V., Christie, T., Tran R., Redmond, W., Bifulco, C., Hilton, T., Dowdell, A., Jensen SM., Paustian C., Patel, A., Hu HM., Bell B., Urba W., Ueda, K., Shimada, T., Piening, B., Leidner, R., Fox, BA.
- Organizer
  The 39th annual Meeting of Society for Immunotherapy of Cancer(SITC) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Identification of naturally presented oncogenic KRAS neoepitope species by mass spectrometry2024
- Author(s)
  1.Minegishi, Y., Ueda, K.
- Organizer
  The 1st International Symposium on Cancer Immunology and Immunotherapy (JACI2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Aberrant Expression of Human Endogenous Retrovirus K9-Derived Elements Is Associated with Better Clinical Outcome of Acute Myelocytic Leukemia.2024
- Author(s)
  Yanagiya, R., Minegishi, Y., Onizuka, M., Ueda, K., Kotani, A. and Nakagawa, S.
- Organizer
  The annual meeting of American Society of Hematology 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Identification of Class I immunopeptide from cancer dark matter.2024
- Author(s)
  Minegishi, Y., Kiyotani, K., Ueda, K.
- Organizer
  第83回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Current Updates for Immunopeptidomics by ion mobility-assisted mass spectrometry.2024
- Author(s)
  Minegishi, Y., Ueda, K.
- Organizer
  Edgefield Program HNSCC Retreat 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Detection of KRAS G12D/G12V neoepitopes expressed by cancer cell lines using LC-MS/MS2023
- Author(s)
  Iwamoto, N., Minegishi, Y., Ueda, K., Koguchi, Y., Redmond, W., Piening, B., Fox, B.A, Tran, E., Shimada, T.
- Organizer
  The 38th annual Meeting of Society for Immunotherapy of Cancer (SITC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Potential of mass spectrometry in antigen discovery for cancer immunotherapy2023
- Author(s)
  峯岸ゆり子、芳賀淑美、箱崎勇治、清谷一馬、長山聡、植田幸嗣
- Organizer
  第82回日本癌学会学術総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Simultaneous identification of KRAS mutation-carrying multiple neoepitopes by differential ion mobility-assisted targeted-mass spectrometry.2023
- Author(s)
  Minegishi, Y., Iwamoto, N., Shimada, T., Kiyotani, K., Nagayama, S., Tran, E., Koguchi, Y., Redmond, W., Piening, B., Fox, B.A., Ueda, K.
- Organizer
  The 38th annual Meeting of Society for Immunotherapy of Cancer (SITC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] 微分型イオン移動度質量分析によるがん免疫医療のためのイムノペプチドームの探索2023
- Author(s)
  長山聡、峯岸ゆり子、植田幸嗣
- Organizer
  第109回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-23K04971
[Presentation] Explore the immunopeptidome for shared neoantigen by differential ion mobility-mass spectrometry2022
- Author(s)
  峯岸ゆり子、芳賀淑美、清谷一馬、長山聡、植田幸嗣
- Organizer
  第81回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] An effort to catalog the cancer driver mutation-carrying neoantigens for the frontier of immunotherapy2022
- Author(s)
  Minegishi, Y., Kiyotani, K., K, Nemoto, K., Nagayama, S., Ueda, K.
- Organizer
  Human Proteome Organization World Congress (HUPO2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] 微分型イオン移動度質量分析によるがん免疫医療のためのイムノペプチドームの探索2022
- Author(s)
  峯岸ゆり子、清谷一馬、長山聡、植田幸嗣
- Organizer
  日本プロテオーム学会
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] Function of ERAP2 (endoplasmic reticulum aminopeptidase 2) in cancer immunity2021
- Author(s)
  3.Hayashi, N., Ikeda, Y., Okamura, K., Tate, T., Nemoto, K., Nagayama, S., Minegishi, Y., Ueda, K., Kiyotani, K., Nakamura, Y. and Kei Kawana
- Organizer
  The 36th Annual Meeting Japanese Society for Immunology of Reproduction
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] がん免疫個別化医療の実現に向けた高深度・高感度イムノペプチドミクス2021
- Author(s)
  峯岸ゆり子、植田幸嗣
- Organizer
  日本薬学会第142年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] Global immunopeptidomics by differential ion mobility mass spectrometry for identification of patient specific HLA-presented antigens directly from clinical tissues.2021
- Author(s)
  Minegishi, Y., Kiyotani, K., K, Nemoto, K., Nagayama, S., Ueda, K
- Organizer
  Human Proteome Organization World Congress (HUPO2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] プロテオゲノミクス解析による大腸癌組織上HLA提示抗原ペプチドの網羅的同定2020
- Author(s)
  峯岸ゆり子
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K05759
[Presentation] Mutation in Leber’s congenital amaurosis-causing gene cct2 evokes retinal hypoplasia in zebrafish2018
- Author(s)
  Yuriko MINEGISHI
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11472
[Presentation] Mutation in Leber’s congenital amaurosis causing gene, cct2, evokes retinal hypoplasia in zebrafish2018
- Author(s)
  Minegishi, Y., Nakaya, N,m Iwata, T. and Tomarev, S.
- Organizer
  Human Genome Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11472
[Presentation] ゼブラフィッシュを用いたCct2遺伝子変異による網膜病態についての検討2017
- Author(s)
  峯岸ゆり子
- Organizer
  第10回Retinal Research Meeting
- Data Source
  KAKENHI-PROJECT-17K11472
[Presentation] オプチニューリンのアミノ酸E50K変異による遺伝性緑内障の発症機序2014
- Author(s)
  峯岸ゆり子
- Organizer
  第19回東北眼疾患病態研究会
- Place of Presentation
  仙台
- Year and Date
  2014-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-26861481
[Presentation] オプチニューリンのアミノ酸 E50K 変異による遺伝性緑内障の発症機序2014
- Author(s)
  峯岸ゆり子, 岩田岳
- Organizer
  第19回東北眼疾患病態研究会
- Place of Presentation
  仙台
- Year and Date
  2014-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] 緑内障原因遺伝子オプチニューリンとE50K 変異によるタンパクの不溶化と病態発症との関連2013
- Author(s)
  峯岸ゆり子, 家島大輔, 小林宏明, 池在龍, 川瀬和秀, 山本哲也, 関倫久, 湯浅慎介, 福田恵一, 岩田岳
- Organizer
  第17回眼科分子生物学研究会
- Place of Presentation
  静岡
- Year and Date
  2013-02-24
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Etiologic dynamics of optineurin E50K mutant in iPSC from open angle glaucoma patient2013
- Author(s)
  Minegishi, Y., Iwata, T
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2013-11-13
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Distinct protein complex formation evokes insolubility of OPTN and mislocalization in iPSC-derived neural cells from E50K-POAG patients2013
- Author(s)
  Minegishi, Y., Iejima, D., Kobayashi, H., Chi., ZL., Kawase, K., Yamamoto, T., Seki, T., Yuasa, S., Fukuda, K., Iwata, T
- Organizer
  ARVO2013
- Place of Presentation
  Seattle, WA, USA
- Year and Date
  2013-05-05
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Aberrant accumulation of glaucoma-associated OPTN E50K mutant protein potentiates the glaucomatous retinal vulnerability2012
- Author(s)
  Minegishi, Y., Iwata, T
- Organizer
  XX Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] オプチニューリン E50K 変異体による正常眼圧緑内障の病態機序の解明2012
- Author(s)
  峯岸ゆり子, 小林宏明, 家島大輔, 岩田岳
- Organizer
  第5回 Retinal Research Meeting
- Place of Presentation
  東京
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Comparative functional analysis of optineurin and its glaucoma-related mutant E50K by mammalian cell-based LC-MS/MS proteomics2012
- Author(s)
  Minegishi, Y., Kobayashi, H., Iwata, T
- Organizer
  XX Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] オプチニューリンのアミノ酸E50K変異による遺伝性緑内障の発症機序
- Author(s)
  峯岸ゆり子、　岩田岳
- Organizer
  第19回東北眼疾患病態研究会
- Place of Presentation
  仙台、　日本。
- Invited
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Comperative functional analysis of optineurin and its glaucoma-related mutant E50K by mammalian cell-based LC-MS/MS proteomics
- Author(s)
  Minegishi, Y., Kobayashi, H., Iwata
- Organizer
  XX　Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Aberrant accumulation of glaucoma-associated OPTN E50K mutant protein potentiates the glaucomatous retinal vulnerability
- Author(s)
  Minegishi, Y., Iwata
- Organizer
  XX　Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] オプチニューリンE50K変異体による正常眼圧緑内障の病態機序の解明
- Author(s)
  峯岸ゆり子、小林宏明、家島大輔、岩田岳
- Organizer
  The 5th Retinal Research Meeting
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] 緑内障原因遺伝子オプチニューリンとE50K変異によるタンパクの不溶化と病態発症との関連
- Author(s)
  峯岸ゆり子、家島大輔、小林宏明、池在龍、川瀬和秀、山本哲也、関倫久、湯浅慎介、福田恵一、岩田岳
- Organizer
  第17回眼科分子生物学研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Distinct protein complex formation evokes insolubility of OPTN and mislocalization in iPSC-derived neural cells from E50K-POAG patients
- Author(s)
  Minegishi, Y., Iejima, D., Kobayashi, H., Chi1., ZL., Kawase, K., Yamamoto, T., Seki, T., Yuasa, S., Fukuda, K., Iwata, T
- Organizer
  ARVO2013　Annual Meeting
- Place of Presentation
  シアトル、アメリカ
- Data Source
  KAKENHI-PROJECT-24791885
[Presentation] Etiologic dynamics of optineurin E50K mutant in iPSC from open angle glaucoma patient.
- Author(s)
  Minegishi, Y.,　Iwata, T.
- Organizer
  Neuroscience 2013
- Place of Presentation
  サンディエゴ、　アメリカ。
- Data Source
  KAKENHI-PROJECT-24791885

1. Okamoto Akiko (70450400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 中川草 (70510014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 大塚正人 (90372945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 北尾晃一 (20991269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 柳谷稜 (80825779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 世古裕子 (60301157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UEDA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. SUGA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Minegishi Yuriko 峯岸 ゆり子

MINEGISHI Yuriko 峯岸 ゆり子

Research Projects

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Co-Researchers

Development of a Research Platform for Functional Analysis of Proteins Derived from Endogenous Viral Elements in Mammalian Genomes

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Studies on involvement of aging- and immune-related molecules in onset and progression of retinitis pigmentosa using Eys-deficient zebrafish

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Investigation of Target Protein Degradation and Its Effect on Enhancing Cancer-Specific Antigen Presentation by Quantitative Mass SpectrometryPrincipal Investigator

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Generation and analysis of Leber congenital amaurosis mouse model with CCT2 point mutations

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Analysis of the rate-limiting factor for intracellular antigen processing of HLA class I antigen peptidesPrincipal Investigator

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Analysis of retinal function of LCA-causing CCT2 and the generation of mouse model and therapeuticsPrincipal Investigator

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OPTN-E50K変異性正常眼圧緑内障の遺伝子治療に向けた検討Principal Investigator

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Molecular analyses of glaucoma-associated mutations in OPTN gene and retinal blood flowPrincipal Investigator

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[Book] 医用工学ハンドブック2022

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[Book] Retina Medicine2014

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[Book] Retina Medicine Vol3. No2.2014

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[Book] 日本人のヒット論文-本音で語る苦労話-第5回 オプチニューリン E50K 変異による遺伝性緑内障発症の機序『Retina Medicine』(中澤徹編)2014

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[Book] 脳21 Vol.17 No.42014

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[Journal Article] The Japanese-German Symposium on the “Advancement and Application of Proteoform-Centric Proteomics”2025

Author(s)

Minegishi Yuriko 峯岸ゆり子

MINEGISHI Yuriko 峯岸ゆり子

[Book] 日本人のヒット論文-本音で語る苦労話-第5回オプチニューリン E50K 変異による遺伝性緑内障発症の機序『Retina Medicine』(中澤徹編)2014

[Book] 脳21　Vol.17 No.42014