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Mochizuki Kentaro  望月 研太郎

Researcher Number 20633499
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7624-9350
Affiliation (based on the past Project Information) *help 2017 – 2021: 東北大学, 医学系研究科, 大学院非常勤講師
2017: 東北大学, 医学(系)研究科(研究院), 助教
2016: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / General anatomy (including histology/embryology)
Except Principal Investigator
Dental engineering/Regenerative dentistry
Keywords
Principal Investigator
始原生殖細胞 / ヒストン修飾 / SETDB1 / HDAC3 / RNAiスクリーニング / エピゲノム / 多能性細胞 / エピブラスト / エピジェネティクス / 生殖細胞 … More / マウス / 胚発生 / 生殖系列遺伝子 / クロストーク / DNAメチル化 … More
Except Principal Investigator
歯科医用工学 / 神経分化誘導 / 再生医歯学 / SH-SY5Y細胞 / N2A細胞 / 神経成長因子 / 骨形成タンパク質 / サブクローニング / 温熱刺激 / 神経細胞分化 / PC12細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (7 People)
  •  Epigenome dynamics in regulation of germ cell fate via histone modification crosstalkPrincipal Investigator

    • Principal Investigator
      MOCHIZUKI Kentaro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Tohoku University
  •  Comprehensive identification and functional elucidation of regulators of histone modifications that regulate germ cell fatePrincipal Investigator

    • Principal Investigator
      Mochizuki Kentaro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Development of efficient and versatile method for inducing neuronal differentiation with temperature-controlled repeated thermal stimulation (TRTS)

    • Principal Investigator
      Kudo Tada-aki
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Tohoku University

All 2021 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021

    • Author(s)
      Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC.
    • Journal Title

      Nature Communications

      Volume: 12(1) Issue: 1 Pages: 7020-7020

    • DOI

      10.1038/s41467-021-27345-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-17KK0185, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-21K06843
  • [Journal Article] SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling2018

    • Author(s)
      Mochizuki Kentaro, Tando Yukio, Sekinaka Tamotsu, Otsuka Kei, Hayashi Yohei, Kobayashi Misato, Kamio Asuka, Ito-Matsuoka Yumi, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Matsui Yasuhisa
    • Journal Title

      Development

      Volume: 145 Issue: 23 Pages: 1-10

    • DOI

      10.1242/dev.164160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K17594, KAKENHI-PROJECT-18K15001, KAKENHI-PROJECT-17J02039, KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-15H05579, KAKENHI-PUBLICLY-18H04875
  • [Journal Article] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018

    • Author(s)
      Mochizuki Kentaro, Hayashi Yohei, Sekinaka Tamotsu, Otsuka Kei, Ito-Matsuoka Yumi, Kobayashi Misato, Oki Shinya, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Matsui Yasuhisa
    • Journal Title

      Cell Reports

      Volume: 24 Issue: 10 Pages: 2682-2693

    • DOI

      10.1016/j.celrep.2018.07.108

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K17594, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-17J02039, KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-15H05579, KAKENHI-PUBLICLY-18H04875, KAKENHI-PROJECT-18KT0024
  • [Presentation] 初期胚におけるポリコムPRC1.6複合体およびSETDB1による生殖系列遺伝子群の抑制はDNAメチル化を介したサイレンシングに先行する2021

    • Author(s)
      望月研太郎
    • Organizer
      科学研究費新学術領域「非ゲノム情報複製」第12回Webinar
    • Invited
    • Data Source
      KAKENHI-PROJECT-17KK0185
  • [Presentation] Role of histone methylation, and its reader proteins in DNA methylation and silencing of germline genome-defense genes.2019

    • Author(s)
      Kentaro Mochizuki, Kevin Jeffers, Matthew C. Lorincz
    • Organizer
      The 6th Canadian Conference on Epigenetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KK0185
  • [Presentation] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018

    • Author(s)
      Mochizuki Kentaro, Hayashi Yohei, Sekinaka Tamotsu, Otsuka Kei, Ito-Matsuoka Yumi, Kobayashi Misato, Oki Shinya, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Lorincz Matthew, Matsui Yasuhisa
    • Organizer
      The 5th Canadian Conference on Epigenetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17594
  • [Presentation] Hdac3 recruitment on somatic developmental genes by Blimp1 and their repression is essential for mouse primordial germ cell fate determination2017

    • Author(s)
      Kentaro Mochizuki, Hisato Kobayashi, Yumi Matsuoka, Tomohiro Kono, Noriko Osumi, Yasuhisa Matsui
    • Organizer
      日本発生生物学会 第50回大会
    • Data Source
      KAKENHI-PROJECT-17K17594
  • 1.  Kudo Tada-aki (50431606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  野口 拓也 (20431893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  冨並 香菜子 (10815351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  出江 紳一 (80176239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  金高 弘恭 (50292222)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  高木 敏行 (20197065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  浦西 洸介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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