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Yoshimoto Taichiro  吉本 多一郎

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YOSHIMOTO TAICHIRO  吉本 多一郎

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Researcher Number 20634166
Other IDs
Affiliation (Current) 2025: 自治医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2019 – 2021: 自治医科大学, 医学部, 非常勤講師
2015 – 2018: 自治医科大学, 医学部, 講師
2013 – 2014: 自治医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Human pathology
Except Principal Investigator
Human pathology / Basic Section 49020:Human pathology-related
Keywords
Principal Investigator
肺腺癌 / 上皮間葉転換 / 肺癌 / インターラクトーム / 癌間質相互作用 / EMT / non-coding RNA / ノンコーディングRNA
Except Principal Investigator
上皮間葉転換 / 肺腺癌 … More / 肺癌 / 病理組織 / 細胞分化 / 分子標的 / エピジェネティクス / メチル化 / 分化形質 / エピジェネティックス / マウス / 転移 Less
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (6 People)
  •  Integrated regulatory mechanism that govern differentiation and survival of driver-mutation-independent lung adenocarcinoma

    • Principal Investigator
      niki toshiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Jichi Medical University
  •  Interactome analysis of the pulmonary adenocarcinoma.Principal Investigator

    • Principal Investigator
      Yoshimoto Taichiro
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Jichi Medical University
  •  Epigenetic abnormalities and reprogramming in epithelial-mesenchymal transition of lung adenocarcinoma

    • Principal Investigator
      Niki Toshiro
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Jichi Medical University
  •  Systemic generation of metastatic models of lung adenocarcinoma

    • Principal Investigator
      niki toshiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Jichi Medical University
  •  Exploration of long non-coding RNA involved in epithelial mesenchymal transition in non-small cell lung cancer.Principal Investigator

    • Principal Investigator
      Yoshimoto Taichiro
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Jichi Medical University

All 2020 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

  • [Journal Article] Reciprocal expression of trefoil factor‐1 and thyroid transcription factor‐1 in lung adenocarcinomas2020

    • Author(s)
      Matsubara Daisuke、Yoshimoto Taichiro、Soda Manabu、Amano Yusuke、Kihara Atsushi、Funaki Toko、Ito Takeshi、Sakuma Yuji、Shibano Tomoki、Endo Shunsuke、Hagiwara Koichi、Ishikawa Shumpei、Fukayama Masashi、Murakami Yoshinori、Mano Hiroyuki、Niki Toshiro
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 6 Pages: 1-13

    • DOI

      10.1111/cas.14403

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K10094, KAKENHI-PROJECT-19K16565, KAKENHI-PROJECT-18H02634
  • [Journal Article] Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.2017

    • Author(s)
      Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Tamura T, Oguni S, Katashiba S, Ito T, Murakami Y, Fukayama M, Murakami T, Endo S, Niki T.
    • Journal Title

      Plos One

      Volume: 12 Issue: 8 Pages: e0181342-e0181342

    • DOI

      10.1371/journal.pone.0181342

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-17K16615, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26461700
  • [Journal Article] Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.2017

    • Author(s)
      Matsubara D, Soda M, Yoshimoto T, Amano Y, Sakuma Y, Yamato A, Ueno T, Kojima S, Shibano T, Hosono Y, Kawazu M, Yamashita Y, Endo S, Hagiwara K, Fukayama M,Takahashi T, Mano H, Niki T.
    • Journal Title

      Cancer Sci

      Volume: 108 Issue: 9 Pages: 1888-1896

    • DOI

      10.1111/cas.13313

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-17K07250, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H02468
  • [Journal Article] 高度な骨髄癌腫症とPulmonary tumor thrombotic microangiopathyを合併した胃癌の一剖検例2016

    • Author(s)
      吉本多一郎、田野茂夫、福嶋敬宜、仁木利郎
    • Journal Title

      病理と臨床

      Volume: 34(1) Pages: 83-86

    • Data Source
      KAKENHI-PROJECT-25860275
  • [Journal Article] Frequent loss of the expression of multiple subunits of the SWI/SNF complex in large cell carcinoma and pleomorphic carcinoma of the lung.2015

    • Author(s)
      Yoshimoto T, Matsubara D, Nakano T, Tamura T, Endo S, Sugiyama Y, Niki T.
    • Journal Title

      Pathology international

      Volume: 35 Issue: 11 Pages: 595-602

    • DOI

      10.1111/pin.12350

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080
  • [Journal Article] Immunohistochemical analysis of the expression of E-cadherin and ZEB1 in non-small cell lung cancer.2014

    • Author(s)
      Matsubara D, Kishaba Y, Yoshimoto T, Sakuma Y, Sakatani T, Tamura T, Endo S, Sugiyama Y, Murakami Y, Niki T
    • Journal Title

      Pathology International

      Volume: 64 Issue: 11 Pages: 560-568

    • DOI

      10.1111/pin.12214

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26640121
  • [Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018

    • Author(s)
      31.Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
    • Organizer
      Annual Meeting of American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02634
  • [Presentation] MUC21 is a candidate key molecule involved in the incohesive growth pattern of lung adenocarcinoma.2018

    • Author(s)
      Yoshimoto T, Matsubara D, Soda M, Amano Y, Kihara A, Nakano T, Shibano T, Endo S, Hagiwara K, Denda-Nagai K, Irimura T, Mano H, Niki T.
    • Organizer
      6th JCA-AACR Special Joint Conference
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Long-term, 3-dimensional spheroid culture: a putative model to study evolution of detached cancer cells in tumor metastasis.2018

    • Author(s)
      Shibano T, nakano T, Kanai Y, Yoshimoto T, Amano Y, Matsubara D, Murakami T, Endo S, Niki T.
    • Organizer
      17th Biennial Congress of Metastatic Research Society
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018

    • Author(s)
      Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
    • Organizer
      Annual Meeting of American Association for Cancer Research
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] 3D Low-Attachment Culture: A Putative Model for STAS And "Floating" Cancer Cells.2017

    • Author(s)
      Nakano T, Yoshimoto T, Kanai Y, Shibano T, Matsubara D, Endo S, Niki T.
    • Organizer
      18th World Conference of Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Mutation of SWI/SNF Complex Genes Is Frequent in Poorly Differentiated, Mesenchymal-Like Lung Cancer without Major Driver Mutation.2017

    • Author(s)
      Yoshimoto T, Matsubara D, Niki T.
    • Organizer
      18th World Conference of Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Establishment of Highly Metastatic Lung Cancer Cell Sublines in Long-term Three-dimensional Low Attachment Cultures.2017

    • Author(s)
      Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Endo S, Niki T.
    • Organizer
      18th World Conference of Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Interactome analysis of lung adenocarcinoma in Xenograft model2016

    • Author(s)
      吉本多一郎、松原大祐、河村大輔、石川俊平、仁木利郎
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] 病理組織学的アプローチによるNon-TRUタイプ肺腺癌のNKX2-1遺伝子変異の同定2016

    • Author(s)
      松原 大祐、曽田 学, 吉本 多一郎, 天野 雄介, 上野 敏秀, 小島 進也, 間野 博行, 仁木 利郎
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] 肺癌の上皮間葉転換におけるクロマチンリンモデリング因子異常の解析2016

    • Author(s)
      吉本多一郎、松原大祐、福嶋敬宜、仁木利郎
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] 系統的肺腺癌ゼノグラフトを用いた癌間質相互作用の解析2016

    • Author(s)
      吉本多一郎、松原大祐、河村大輔、石川俊平、仁木利郎
    • Organizer
      日本病理学会カンファランス
    • Place of Presentation
      兵庫県神戸市六甲山ホテル
    • Year and Date
      2016-07-29
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] 系統的肺腺癌ゼノグラフトを用いた癌間質相互作用の解析2016

    • Author(s)
      吉本多一郎, 松原大祐, 河村大輔, 石川俊平, 仁木利郎
    • Organizer
      第57回日本肺癌学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県、福岡市)
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] Frequent mutation of SWI/SNF complex genes in lung cancer cell lines with EMT-phenotype.2016

    • Author(s)
      吉本多一郎、松原大祐、福嶋敬宜、仁木利郎
    • Organizer
      第105回日本病理学会
    • Place of Presentation
      宮城県仙台市仙台国際センター
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] Altered expressions of multiple subunits of the switch/sucrose non-fermenting (SWI/SNF) complex in Non-small cell lung cancer.2015

    • Author(s)
      Yoshimoto T, Matsubara D, Niki T.
    • Organizer
      AACR special meeting
    • Place of Presentation
      Atlanta
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-25670178
  • [Presentation] Altered expressions of multiple subunits of the switch/sucrose non-fermenting (SWI/SNF) complex in Non-small cell lung cancer.2015

    • Author(s)
      Yoshimoto T, Matsubara D, Niki T.
    • Organizer
      AACR special meeting
    • Place of Presentation
      Atlanta
    • Year and Date
      2015-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293080
  • [Presentation] 部分的にp40陽性を示した肺腺癌の2例2014

    • Author(s)
      吉本多一郎、仁木利郎
    • Organizer
      第103回日本病理学会
    • Place of Presentation
      広島市
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] Molecular Mechanisms for EMT in Lung cancer; Relationship with Chromatin Remodeling Factors and Mutation of EGFR Gene2013

    • Author(s)
      吉本多一郎、松原大祐、佐久間裕司、仁木利郎
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] Molecular mechanisms for EMT in lung cancer; relationship with chromatin remodeling factors and mutation of EGFR.2013

    • Author(s)
      Yoshimoto T, Niki T, Matsubara D.
    • Organizer
      72th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-25670178
  • [Presentation] 肺癌における上皮間葉転換の分子機構2013

    • Author(s)
      吉本多一郎、松原大祐、佐久間裕司、仁木利郎
    • Organizer
      第10回日本病理学会カンファレンス
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] RET融合遺伝子を有する肺腺癌細胞株の発見2013

    • Author(s)
      松原大祐、石川俊平、小原詩織、吉本多一郎、坂谷貴司、片岡寛章、村上善則、油谷浩幸、深山正久、仁木利郎.
    • Organizer
      日本病理学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670178
  • [Presentation] Peripheral mixed squamous and glandular papillary tumorの2例2013

    • Author(s)
      吉本多一郎、佐久間裕司、仁木利郎
    • Organizer
      第54回日本肺癌学会総会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-25860275
  • [Presentation] 通常型間質性肺炎に生じた腸型形質を示す肺原発腺癌の一例2013

    • Author(s)
      吉本多一郎、松原大祐、佐久間裕司、仁木利郎
    • Organizer
      第102回日本病理学会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-25860275
  • 1.  niki toshiro (90198424)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 2.  佐久間 裕司 (10364514)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  松原 大祐 (80415554)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 4.  萩原 弘一 (00240705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  遠藤 俊輔 (10245037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  村上 善則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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