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Saito Takuro  西塔 拓郎

ORCIDConnect your ORCID iD *help
Researcher Number 20646468
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 助教
2021: 大阪大学, 医学系研究科, 助教
2020: 大阪大学, 医学系研究科, 特任助教(常勤)
2020: 大阪大学, 大学院医学系研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 50010:Tumor biology-related / Basic Section 56030:Urology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 59010:Rehabilitation science-related
Keywords
Principal Investigator
免疫チェックポイント分子 / T細胞疲弊化 / リンパ節 / 胃癌 / Precursor T細胞 / 抗PD1抗体 / 所属リンパ節 / 免疫抑制機構 / 胃癌リンパ節 / PD1 / PD-L1 / PD-1 / エクソソーム … More
Except Principal Investigator
… More 制御性T細胞 / CCL1 / CCR8 / 腫瘍免疫環境 / ISH法 / CCR8発現細胞 / CCL1発現細胞 / 血液 / 細菌叢 / Dアミノ酸 / CD31 / 血管新生 / 尿路上皮癌 / 腎細胞癌 / エクソソーム / Cutibacterium acnes / 細胞外小胞 / Firmicutes / 癌免疫療法 / 細菌関連代謝物 / 血液内細菌叢 / 術前除菌 / ICOS / H. pylori / ICOS+ Treg / 除菌 / H.pylori / ICOS陽性Treg / 胃癌 / スリーブ状胃切除 / 2型糖尿病 / 腸内細菌叢 / 減量効果・糖尿病 改善効果 / 腹腔鏡下スリーブ状胃切除術 / 減量・代謝改善手術 / 栄養療法 / 術前リハビリテーション / 筋肉量 / アプリ / リハビリテーション / 術前リハ栄養 / 栄養 / リハビリ / サルコペニア / 癌治療 / 高齢者 / 術前化学療法 / 食道癌 / 運動栄養介入 / 運動・栄養介入 / フレイル / 高齢癌患者 Less
  • Research Projects

    (8 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (25 People)
  •  CCL1-CCR8経路を介した腫瘍内Treg制御による治療法の探索

    • Principal Investigator
      中井 慈人
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka University
  •  ニボルマブ結合T細胞検出法を用いた免疫チェックポイント阻害薬の治療効果機序の解明Principal Investigator

    • Principal Investigator
      西塔 拓郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka University
  •  周術期H.pylori除菌の胃癌予後改善効果:ICOS発現Tregの制御

    • Principal Investigator
      浦川 真哉
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka University
  •  Elucidation of the cancer local immune status constructed by the systemic circulating microbiome and bacterial-related metabolism in urogenital cancer

    • Principal Investigator
      河嶋 厚成
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Development of preoperative rehabilitation and nutritional support program for improving treatment outcome of elderly gastric cancer patients

    • Principal Investigator
      Yamamoto Kazuyoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Osaka University
  •  腸内細菌叢(特にAM菌)と肥満・糖尿病外科手術後減量・糖尿病改善効果の関連の解明

    • Principal Investigator
      山口 剛
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Shiga University of Medical Science
  •  A trial of exercise and nutrition treatment for aged esophageal cancer patients undergoing neoadjuvant chemotherapy

    • Principal Investigator
      YAMASAKI Makoto
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kansai Medical University
      Osaka University
  •  The analysis for the suppressive mechanism of antitumor immunity in lymph nods of gastric cancerPrincipal Investigator

    • Principal Investigator
      Saito Takuro
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka University

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024

    • Author(s)
      Jingushi Kentaro、Kawashima Atsunari、Tanikawa Sayaka、Saito Takuro、Yamamoto Akinaru、Uemura Toshihiro、Sassi Nesrine、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Hase Hiroaki、Nonomura Norio、Tsujikawa Kazutake
    • Journal Title

      Cancer Science

      Volume: 1 Issue: 8 Pages: 1-1

    • DOI

      10.1111/cas.16202

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Journal Article] Integrated analysis of phase 1a and 1b randomized controlled trials; Treg-targeted cancer immunotherapy with the humanized anti-CCR4 antibody, KW-0761, for advanced solid tumors2023

    • Author(s)
      Fujikawa Kaoru、Saito Takuro、Kurose Koji、Kojima Takashi、Funakoshi Takeru、Sato Eiichi、Kakimi Kazuhiro、Iida Shinsuke、Doki Yuichiro、Oka Mikio、Ueda Ryuzo、Wada Hisashi
    • Journal Title

      PLOS ONE

      Volume: 18 Issue: 9 Pages: 0291772-0291772

    • DOI

      10.1371/journal.pone.0291772

    • Data Source
      KAKENHI-PROJECT-23K08194
  • [Journal Article] C-reactive protein kinetics as a predictive marker for long-term outcome of immune checkpoint inhibitors in oesophagogastric cancer2023

    • Author(s)
      Nose Yohei、Saito Takuro、Kurokawa Yukinori、Takahashi Tsuyoshi、Yamamoto Kazuyoshi、Momose Kota、Yamashita Kotaro、Tanaka Koji、Makino Tomoki、Eguchi Hidetoshi、Doki Yuichiro、Wada Hisashi
    • Journal Title

      BJC Reports

      Volume: 1 Issue: 1 Pages: 7-7

    • DOI

      10.1038/s44276-023-00005-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K08194
  • [Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023

    • Author(s)
      Uemura Toshihiro、Kawashima Atsunari、Jingushi Kentaro、Motooka Daisuke、Saito Takuro、Nesrine Sassi、Oka Toshiki、Okuda Yohei、Yamamoto Akinaru、Yamamichi Gaku、Tomiyama Eisuke、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
    • Journal Title

      Heliyon

      Volume: 9 Issue: 9 Pages: e19800-e19800

    • DOI

      10.1016/j.heliyon.2023.e19800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09469, KAKENHI-PROJECT-23K24472
  • [Journal Article] Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors.2023

    • Author(s)
      Hayashi Y, Makino T, Sato E, Ohshima K, Nogi Y, Kanemura T, Honma K, Yamashita K, Saito T, Tanaka K, Yamamoto K, Takahashi T, Kurokawa Y, Miyata H, Nakajima K, Wada H, Morii E, Eguchi H, Doki Y.
    • Journal Title

      Br J Cancer.

      Volume: - Issue: 12 Pages: 2175-2185

    • DOI

      10.1038/s41416-023-02235-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08776, KAKENHI-PROJECT-22K07278, KAKENHI-PROJECT-23K08194
  • [Journal Article] Propranolol suppresses gastric cancer cell growth by regulating proliferation and apoptosis2021

    • Author(s)
      Koh Masahiro、Takahashi Tsuyoshi、Kurokawa Yukinori、Kobayashi Teruyuki、Saito Takuro、Ishida Tomo、Serada Satoshi、Fujimoto Minoru、Naka Tetsuji、Wada Noriko、Yamashita Kotaro、Tanaka Koji、Miyazaki Yasuhiro、Makino Tomoki、Nakajima Kiyokazu、Yamasaki Makoto、Eguchi Hidetoshi、Doki Yuichiro
    • Journal Title

      Gastric Cancer

      Volume: 24 Issue: 5 Pages: 1037-1049

    • DOI

      10.1007/s10120-021-01184-7

    • NAID

      40022652391

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17685
  • [Journal Article] Taste alteration after gastrectomy in patients with gastric cancer2021

    • Author(s)
      Hagi Takaomi、Kurokawa Yukinori、Takahashi Tsuyoshi、Saito Takuro、Yamashita Kotaro、Tanaka Koji、Makino Tomoki、Yamasaki Makoto、Motoori Masaaki、Kimura Yutaka、Nakajima Kiyokazu、Eguchi Hidetoshi、Doki Yuichiro
    • Journal Title

      Surgery Today

      Volume: 51 Issue: 5 Pages: 777-784

    • DOI

      10.1007/s00595-020-02194-1

    • Data Source
      KAKENHI-PROJECT-20K17685
  • [Presentation] CRP推移による胃癌免疫チェックポイント阻害薬のアウトカム予測2023

    • Author(s)
      西塔拓郎
    • Organizer
      第27回日本がん免疫学会
    • Data Source
      KAKENHI-PROJECT-23K08194
  • [Presentation] CRP kinetics as a predictive marker for outcome to immune checkpoint inhibitors in upper gastrointestinal cancer2023

    • Author(s)
      西塔拓郎
    • Organizer
      第82回日本癌学会
    • Data Source
      KAKENHI-PROJECT-23K08194
  • [Presentation] 術前ピロリ菌除菌が抗腫瘍免疫を介して胃癌の予後に与える影響2022

    • Author(s)
      西塔拓郎
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-22K08846
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 2 results
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  • 5.  牧野 知紀 (80528620)
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    # of Collaborated Products: 1 results
  • 6.  高橋 剛 (50452389)
    # of Collaborated Projects: 2 results
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  • 7.  YAMASAKI Makoto (50444518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Yamamoto Kazuyoshi (70528637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松浦 記大 (90804477)
    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  太田 正之 (80271104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  井上 健太郎 (90368209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  加野 将之 (20456023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  浦川 真哉 (40768975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  河嶋 厚成 (50746568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  木村 友則 (00631300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  元岡 大祐 (10636830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  神宮司 健太郎 (80707571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  中井 慈人 (40912027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  植村 俊彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  土岐 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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