YANO HIROKAZU 矢野大和

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YANO Hirokazu 矢野大和

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Researcher Number	20646773
Other IDs	https://orcid.org/0000-0001-5144-3459
Affiliation (Current)	2026: 国立健康危機管理研究機構, 国立感染症研究所薬剤耐性研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2026: 国立健康危機管理研究機構, 国立感染症研究所薬剤耐性研究センター, 主任研究員 2025: 国立健康危機管理研究機構, 薬剤耐性研究センター, 主任研究官 2021 – 2024: 国立感染症研究所, 薬剤耐性研究センター, 主任研究官 2018 – 2021: 東北大学, 生命科学研究科, 講師 2016 – 2017: 筑波大学, 生命環境系, 研究員 2014 – 2015: 東京大学, 大学院新領域創成科学研究科, 特任助教 2013 – 2015: 東京大学, 新領域創成科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 38020:Applied microbiology-related / Applied microbiology / Basic Section 45020:Evolutionary biology-related Except Principal Investigator Basic Section 40030:Aquatic bioproduction science-related / Genetics/Chromosome dynamics / Aquatic bioproduction science / Evolutionary biology
Keywords	Principal Investigator 非結核性抗酸菌 / プラスミド / 抗酸菌 / ゲノム / 制限修飾系 / メチローム / ピロリ菌 / トランスクリプトーム / エピゲノム / インテグラーゼ … More / 転移因子 / 集団ゲノム / GWAS / 巨大線状プラスミド / 接合 / 地域適応 / 遺伝的集団構造 / 系統進化 / 集団ゲノミクス / エピジェネティクス / 酸化ストレス / DNAメチル化 … More Except Principal Investigator 養殖場 / 遺伝子伝達 / ビブリオ属 / トランスポゾン / プラスミド / 多剤耐性 / 薬剤耐性菌 / ピロリ菌 / 制限修飾系 / βラクタマーゼ / 多剤耐性プラスミド / ベータラクタマーゼ / SE / チロシンリコンビナーゼ / 塩基除去 / 細菌 / 制限酵素 / エピジェネティクス / 薬剤耐性遺伝子 / ビブリオ属細菌 / インテグレーション / 多剤耐性菌 / インテグラーゼ / 染色体への組み込み / 薬剤耐性 / bcp遺伝子 / 部位特異的挿入 / 染色体 / Tn6283 / pSEA1 / 接合 / 遺伝学 / バイオテクノロジー / ゲノム / 進化 / DNAメチル化 / 集団構造 / トランスクリプトーム / メチローム / 適応進化 / DNA修復 / APエンドヌクレアーゼ / APリアーゼ / キャンピロバクター / DNA切断酵素 / DNA グリコシラーゼ / AP リアーゼ Less

Elucidation of integration factors and maintenance mechanisms of multidrug-resistant plasmids in aquaculture environments
- Principal Investigator
  
  野中里佐
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40030:Aquatic bioproduction science-related
- Research Institution
  Shokei University
実験と生物情報解析に基づくヒッチハイカー型組み込み因子群の転移機構と宿主域の解明Principal Investigator
- Principal Investigator
  
  矢野大和
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Japan Institute for Health Security
Pangenome-phenotype association analysis reveals niche adaptation mechanisms of slow-growing mycobacteriaPrincipal Investigator
- Principal Investigator
  
  矢野大和
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  National Institute of Infectious Diseases
The effects of antibiotics to the transfer frequency of the antibiotic resistance genes and the evolution of high-level resistance.
- Principal Investigator
  
  野中里佐
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40030:Aquatic bioproduction science-related
- Research Institution
  Shokei University
Addressing a model of mycobacterium evolution via sexual reproduction: approaches by molecular genetics and population genomicsPrincipal Investigator
- Principal Investigator
  
  Yano Hirokazu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  Tohoku University
Transposition mechanisms of multiple drug resistance genes from plasmids to chromosome among bacteria in the aquaculture environment
- Principal Investigator
  
  Lisa Nonaka
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40030:Aquatic bioproduction science-related
- Research Institution
  Shokei University
  Dokkyo Medical University
The epigenetics-driven adaptive evolution concept and its application to microbe engineeringPrincipal Investigator
- Principal Investigator
  
  Yano Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  University of Tsukuba
  The University of Tokyo
Base-excision restriction enzymes: structure, function and epigenetics
- Principal Investigator
  
  KOBAYASHI Ichizo
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  The University of Tokyo
Mobile genetic elements associated with multi-drug resistance in the bacteria from aquaculture environments
- Principal Investigator
  
  Lisa Nonaka
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic bioproduction science
- Research Institution
  Dokkyo Medical University
Base excising restriction enzymes
- Principal Investigator
  
  KOBAYASHI Ichizo
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  The University of Tokyo
Mechanisms underlying target specificity changes of DNA methyltransferase, and its application to epigenome breedingPrincipal Investigator
- Principal Investigator
  
  Yano Hirokazu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Adaptive evolution through digital changes in the epigenome
- Principal Investigator
  
  KOBAYASHI Ichizo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Evolutionary biology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Mobile class A β-lactamase gene blaGMA-12024
- Author(s)
  Yano Hirokazu、Suzuki Masato、Nonaka Lisa
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 12 Issue: 1 Pages: 1-13
- DOI
  10.1128/spectrum.02589-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05790, KAKENHI-PROJECT-23K06556, KAKENHI-PROJECT-18K05790
[Journal Article] Host range of strand-biased circularizing integrative elements: a new class of mobile DNA elements nesting in Gammaproteobacteria2023
- Author(s)
  Idola Desmila、Mori Hiroshi、Nagata Yuji、Nonaka Lisa、Yano Hirokazu
- Journal Title
  
  Mobile DNA
  
  Volume: 14 Issue: 1 Pages: 1-23
- DOI
  10.1186/s13100-023-00295-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05790, KAKENHI-PROJECT-18K05790, KAKENHI-PROJECT-22K19124, KAKENHI-PLANNED-21H05315, KAKENHI-PROJECT-23K23500
[Journal Article] Host range of strand-biased circularizing integrative elements: a new class of mobile DNA elements nesting in Gammaproteobacteria2022
- Author(s)
  Desmila Idola, Hiroshi Mori, Yuji Nagata, Lisa Nonaka, Hirokazu Yano
- Journal Title
  
  Research Square
  
  Volume: -
- DOI
  10.21203/rs.3.rs-1499202/v1
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05790
[Journal Article] Atypical integrative element with strandbiased circularization activity assists interspecies antimicrobial resistance gene transfer from Vibrio alfacsensis2022
- Author(s)
  Lisa Nonaka, Michiaki Masuda, Hirokazu Yano
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 8 Pages: 1-24
- DOI
  10.1371/journal.pone.0271627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05790, KAKENHI-PROJECT-22K05790
[Journal Article] Atypical integrative element with strand-biased circularization activity assists interspecies antimicrobial resistance gene transfer from Vibrio alfacsensis2021
- Author(s)
  Lisa Nonaka, Michiaki Masuda, Hirokazu Yano
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.06.22.449512
- Open Access
- Data Source
  KAKENHI-PROJECT-18K05790
[Journal Article] Reconsidering plasmid maintenance factors for computational plasmid design2019
- Author(s)
  Yano H, Shintani M, Tomita M, Suzuki H, and Oshima T
- Journal Title
  
  Comput. Struct. Biotechnol. J.
  
  Volume: 17 Pages: 70-81
- DOI
  10.1016/j.csbj.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06357, KAKENHI-PLANNED-26106004, KAKENHI-PROJECT-17H04666
[Journal Article] Genetic relatedness of Mycobacterium avium subsp. hominissuis isolates from bathrooms of healthy volunteers, rivers, and soils in Japan with human clinical isolates from different geographical areas2019
- Author(s)
  Arikawa Kentaro、Ichijo Tomoaki、Nakajima Satomi、Nishiuchi Yukiko、Yano Hirokazu、Tamaru Aki、Yoshida Shiomi、Maruyama Fumito、Ota Atsushi、Nasu Masao、Starkova Daria A.、Mokrousov Igor、Narvskaya Olga V.、Iwamoto Tomotada
- Journal Title
  
  Infection, Genetics and Evolution
  
  Volume: 74 Pages: 103923-103923
- DOI
  10.1016/j.meegid.2019.103923
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06357, KAKENHI-PROJECT-18K10041, KAKENHI-PROJECT-16H01782, KAKENHI-PROJECT-17K15490
[Journal Article] The recombination-cold region as an epidemiological marker of recombinogenic opportunistic pathogen Mycobacterium avium2019
- Author(s)
  Yano Hirokazu、Suzuki Haruo、Maruyama Fumito、Iwamoto Tomotada
- Journal Title
  
  BMC Genomics
  
  Volume: 20 Issue: 1 Pages: 752-752
- DOI
  10.1186/s12864-019-6078-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06357, KAKENHI-PROJECT-18K10041, KAKENHI-PROJECT-16H01782
[Journal Article] Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate.2018
- Author(s)
  Nonaka, L., Yamamoto, T., Maruyama, F., Hirose, U., Onishi, Y., Kobayashi, T., Suzuki, S., Nomura, N., Masuda, M. and Yano, H.
- Journal Title
  
  PLos One
  
  Volume: 13 Issue: 6 Pages: e0198613-e0198613
- DOI
  10.1371/journal.pone.0198613
- NAID
  120006715750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01782, KAKENHI-PROJECT-15K07531
[Journal Article] Restriction glycosylases: involvement of endonuclease activities in the restriction process.2017
- Author(s)
  Ming-Zhang Xie, Tomoyuki Matsuzaka, Hirokazu Yano, Yoshikazu Furuta, Toshiaki Nakano, Ken Ishikawa, Masaki Fukuyo, Noriko Takahashi, Yutaka Suzuki, Sumio Sugano, Hiroshi Ide and Ichizo Kobayashi
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 45 Pages: 1392-1403
- DOI
  10.1093/nar/gkw1250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26340023, KAKENHI-PROJECT-15K18665, KAKENHI-PROJECT-17H04666
[Journal Article] Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities2015
- Author(s)
  Masaki Fukuyo, Toshiaki Nakano, Yingbiao Zhang, Yoshikazu Furuta, Ken Ishikawa, Miki Watanabe-Matsui, Hirokazu Yano, Takeshi Hamakawa, Hiroshi Ide, Ichizo Kobayashi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: Vol. 43, No. 5 Issue: 5 Pages: 2841-2852
- DOI
  10.1093/nar/gkv116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J02925, KAKENHI-PLANNED-22131010, KAKENHI-PUBLICLY-24113506, KAKENHI-PROJECT-25291080, KAKENHI-PROJECT-25850049, KAKENHI-PROJECT-26340023, KAKENHI-PROJECT-26650123
[Journal Article] Draft Genome Sequence of Pseudomonas moraviensis R28-S2014
- Author(s)
  Samuel S. Hunter, Hirokazu Yano, Wesley Loftie-Eaton, Julie Hughes, Leen De Gelder, Pieter Stragier, Paul De Vos, Matthew L. Settles, and Eva M. Top
- Journal Title
  
  Genome Announcement
  
  Volume: 2 Issue: 1
- DOI
  10.1128/genomea.00035-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25850049
[Journal Article] Diversification of host range within the IncP-1 plasmid group2013
- Author(s)
  Yano, H., Rogers, L.M., Molly K., Heuer, H., Smalla, K., Brown C.J., and Top E.M.
- Journal Title
  
  Microbiology
  
  Volume: 159 Issue: Pt_11 Pages: 23032315-23032315
- DOI
  10.1099/mic.0.068387-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25850049
[Journal Article] Diverse broad-host-range plasmids from freshwater carry few accessory genes2013
- Author(s)
  Brown C.J., Sen D., Yano H., Bauer M.L., Rogers L.M., Van der Auwera G.A., and Top E.M.
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 79 Issue: 24 Pages: 76847695-76847695
- DOI
  10.1128/aem.02252-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] 養殖環境細菌集団における新規ベーターラクタマーゼ遺伝子blaGMA-1の伝播2024
- Author(s)
  野中里佐、矢野桂子、佐藤萌乃華、中別府真希、中村果鈴、山中理紅、松坂美空、阪本伶華、矢野憲一、矢野大和
- Organizer
  九州微生物フォーラム2024
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] 可動性βーラクタマーゼ遺伝子blaGMA-1が付与する性質とその周辺構造2024
- Author(s)
  矢野大和、鈴木仁人、野中里佐
- Organizer
  第37回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] 新しい可動遺伝因子グループSE の転移経路と宿主域2023
- Author(s)
  矢野大和、イドラデスミラ、森宙史、永田裕二、野中里佐
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] 原核生物における新しい可動遺伝因子グループSE (Strand-biased Circularizing Integrative Element) の発見2023
- Author(s)
  矢野大和、Idola Desmila、森　宙史、永田裕二、野中里佐
- Organizer
  第95回日本遺伝学会
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] 養殖環境細菌集団における新規ベーターラクタマーゼ遺伝子blaGMA-1の伝播2023
- Author(s)
  野中里佐、矢野桂子、佐藤萌乃華、中別府真希、中村果鈴、山中理紅、松坂美空、阪本伶華、矢野憲一、矢野大和
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] 養殖環境細菌集団における新規ベーターラクタマーゼ遺伝子blaGMA-1の伝播2023
- Author(s)
  野中里佐、矢野桂子、佐藤萌乃華、中別府真希、中村果鈴、山中理紅、松坂美空、阪本伶華、矢野憲一、矢野大和
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] 原核生物における新しい可動遺伝因子グループSE (Strand-biased Circularizing Integrative Element) の発見2023
- Author(s)
  矢野大和、Idola Desmila、森　宙史、永田裕二、野中里佐
- Organizer
  第95回日本遺伝学会
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] 新しい可動遺伝因子グループSE の転移経路と宿主域2023
- Author(s)
  矢野大和、イドラデスミラ、森宙史、永田裕二、野中里佐
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] GWAS approach identifies bacterial risk factors for cavitary MAC lung diseases2023
- Author(s)
  Hirokazu Yano, Kentero Arikawa, Yukiko Nishiuchi, Hanako Funano, Kana Misawa, Tomoyasu Nishimura, Atsushi Ota, Fumito Maruyama, Mari Miki, Manabu Ato, Naoki Hasegwa, Hiroshi Kida, Ho Namkoong, Seigo Kitada, Tomotada Iwamoto
- Organizer
  第９６回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-23K21162
[Presentation] 鎖バイアスのある環状化を行う新奇インテグレイティブ・エレメントの発見（Discovery of integrative elements with strand-biased circularization activity）2022
- Author(s)
  矢野大和、増田道明、野中里佐
- Organizer
  第95回日本細菌学会大会
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] 鎖バイアスのある環状化を行う新奇可動遺伝因子SE (strand-biased circularizing integrative element)の提唱2022
- Author(s)
  矢野大和、野中里佐
- Organizer
  第35回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-22K05790
[Presentation] 鎖バイアスのある環状化を行う新奇可動遺伝因子SE (strand-biased circularizing integrative element)の提唱2022
- Author(s)
  矢野大和、野中里佐
- Organizer
  第35回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] GWASアプローチによる肺MAC症の病態に関連する細菌側因子の探索2021
- Author(s)
  矢野大和, 西内由紀子, 有川健太郎, 大田篤, 三木真理, 丸山史人, 木田博, 北田清悟, 岩本朋忠
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] ISのように動く非接合型インテグレーティブ・エレメントの発見2020
- Author(s)
  矢野大和
- Organizer
  進化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05790
[Presentation] Local diversification of MAC lung disease agent Mycobacterium avium2020
- Author(s)
  Hirokazu Yano, Fumito Maruyama, Yukiko Nishiuchi, Tomotada Iwamoto
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] Population evolution of　recombinogenic opportunistic pathogen Mycobacterium avium2019
- Author(s)
  Hirokazu Yano, Fumito Maruyama, Tomotada Iwamoto
- Organizer
  第92回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] 肺MAC症原因菌Mycobacterium aviumの地域多様化2019
- Author(s)
  矢野大和、丸山史人、岩本朋忠
- Organizer
  第１回遺伝学会春季分科会国立遺伝学研究所　2019年3月8日
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] 肺MAC症原因菌Mycobacterium aviumのゲノム疫学2019
- Author(s)
  矢野大和、丸山史人、西内由紀子、岩本朋忠
- Organizer
  第4回抗酸菌研究会
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] 肺MAC症原因菌Mycobacterium aviumのゲノム疫学2019
- Author(s)
  矢野大和
- Organizer
  第73回日本細菌学会東北支部総会
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] tRNAアレーを運ぶ線状プラスミドの発見2019
- Author(s)
  矢野大和、永田裕二、丸山史人、西内由紀子、岩本朋忠
- Organizer
  第13回細菌学若手コロッセウム
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] モザイクゲノム生物非結核性抗酸菌の集団進化2018
- Author(s)
  矢野大和、丸山史人、岩本朋忠
- Organizer
  生命科学フロンティアミーティング国立遺伝学研究所 2018年10月5日－7日
- Data Source
  KAKENHI-PROJECT-18K06357
[Presentation] 養殖場由来Vibrio属細菌が保有する伝達性多剤耐性プラスミドpSEA1のTn6283を介した受容菌染色体への組み込み機構2018
- Author(s)
  野中里佐、山本達也、丸山史人、広瀬　侑、大西勇輝、小林　剛、鈴木　聡、野村暢彦、増田道明、矢野大和
- Organizer
  日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-15K07531
[Presentation] Population structure and local adaptation of MAC lung disease agent Mycobacterium avium subsp. hominissuis2018
- Author(s)
  Hirokazu Yano, Tomotada Iwamoto, Yukiko Nishiuchi, Chie Nakajima, Daria A. Starkova, Igor Mokrousov, Olga Narvskaya, Shiomi Yoshida, Kentaro Arikawa, Noriko Nakanishi, Ken Osaki, Ichiro Nakagawa, Manabu Ato, Yasuhiko Suzuki, and Fumito Maruyama
- Organizer
  日本進化学会京都大学吉田キャンパス 2017年８月24-26日
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] Population structure and local adaptation of MAC lung disease agent Mycobacterium avium subsp. hominissuis2018
- Author(s)
  Hirokazu Yano, Tomotada Iwamoto, Yukiko Nishiuchi, Chie Nakajima, Daria A. Starkova, Igor Mokrousov, Olga Narvskaya, Shiomi Yoshida, Kentaro Arikawa, Noriko Nakanishi, Ken Osaki, Ichiro Nakagawa, Manabu Ato, Yasuhiko Suzuki, and Fumito Maruyama
- Organizer
  The 52nd US-Japan Mycobacteria Panel Meeting 2018 in Niigata, Japan, March 15-16, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] 種内相互組み換えによって促進される鳥型結核菌の地域適応2017
- Author(s)
  矢野大和、丸山史人、西内由紀子、中川一路、中島千絵、鈴木定彦、岩本朋忠
- Organizer
  日本ゲノム微生物学会2017年度大会
- Place of Presentation
  慶応大学湘南藤沢キャンパス（神奈川県藤沢市）
- Year and Date
  2017-03-02
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] III 型制限修飾系によるピロリ菌の適応形質とゲノミックアイランドの制御2016
- Author(s)
  矢野大和、林原恵美子、古田芳一、柴山恵吾、小林一三
- Organizer
  第22回ヘリコバクター学会学術集会
- Place of Presentation
  別府国際コンベンションセンターB-CON PLAZA (大分県別府市)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] Epigenetic network of gene expression involving DNA methyltransferases2016
- Author(s)
  Hirokazu Yano, Md Zobaidul Alam, Emirko Rimbara, Yoshikazu Furuta, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayahsi
- Organizer
  第１０会ゲノム微生物学会
- Place of Presentation
  東京工業大学大岡山キャンパス
- Year and Date
  2016-03-03
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] ピロリ菌の適応形質を支配するDNAメチル化系ネットワークの発見2016
- Author(s)
  矢野大和、M Zobaidul Alam, 林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本農芸化学会 2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] ピロリ菌の適応形質を支配するDNAメチル化系ネットワークの発見2016
- Author(s)
  矢野大和、Zobaidul Alam、林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Epigenetic network of gene expression involving DNA methyltransferases2016
- Author(s)
  矢野大和、Zobaidul Alam、林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  第10回ゲノム微生物学会
- Place of Presentation
  東京工業大学（東京都目黒区）
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Methylome Diversification in Human Gastric Pathogen Helicobacter pylori2015
- Author(s)
  Yoshikazu Furuta, Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Hiroe Namba-Fukuyo, Tomoko Shibata, Tomoaki Nishiyama, Shuji Shigenobu, Mitsuyasu Hasebe, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  International Symposium of Corrective Gene System “Establishing Next-Generation Genetics”
- Place of Presentation
  奈良春日野国際フォーラム　甍～I・RA・KA～（奈良県奈良市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K14572
[Presentation] ピロリ菌の適応形質を支配するDNAメチル化系ネットワークの発見2015
- Author(s)
  矢野大和、Zobaidul M. Alam、林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本進化学会第17回大会
- Place of Presentation
  中央大学後楽園キャンパス（東京都文京区）
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] メチローム変換に基づく進化2015
- Author(s)
  矢野大和、古田芳一、Zobaidu M. Alam、林原絵美子、柴田朋子、西山智明、重信秀治、長谷部光泰、鈴木穰、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本遺伝学会第８６回大会
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2015-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] Methylome Diversification in Human Gastric Pathogen Helicobacter pylori2015
- Author(s)
  Yoshikazu Furuta, Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Hiroe Namba-Fukuyo, Tomoko Shibata, Tomoaki Nishiyama, Shuji Shigenobu, Mitsuyasu Hasebe, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  International Symposium of Corrective Gene System “Establishing Next-Generation Genetics”
- Place of Presentation
  奈良春日野国際フォーラム　甍～I・RA・KA～（奈良県奈良市）
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] メチローム変換に基づく進化2015
- Author(s)
  矢野大和、古田芳一、Zobaidul Alam、林原絵美子、柴田朋子、鈴木穣、菅野純夫、重信秀治、長谷部光泰、小林一三
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Adaptive evolution and ever metamorphosing DNA methylation systems2015
- Author(s)
  Hirokazu Yano, Yoshikazu Furuta, Zobaidul M. Alam, Emiko Rimbara, Hiroe Namba-Fukuyo, Tomoko Shibata, Tomoaki Nishiyama, Shuji Shigenobu, Mitsuyasu Hasebe, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  7th NEB Meeting on DNA Restriction and Modification
- Place of Presentation
  グダンスク（ポーランド）
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Restriction enzyme with base excision and abasic-site cleavage activities2015
- Author(s)
  Masaki Fukuyo, Toshiaki Nakano, Kenji K. Kojima, Yingbiao Zhang, Yoshikazu Furuta, Ken Ishikawa, Miki Watanabe-Matsui, Hirokazu Yano, Takeshi Hamakawa, Hiroshi Ide and Ichizo Kobayashi
- Organizer
  7th NEB Meeting on DNA Restriction and Modification
- Place of Presentation
  グダンスク（ポーランド）
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14572
[Presentation] Network of DNA methyltransferases behind the adaptive phenotype in Helicobacter pylori, 3P05882015
- Author(s)
  Hirokazu Yano, Zobaidul Alam, Emiko Rimbara, Yoshikazu Furuta, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] 塩基切り出し型制限酵素という驚き2015
- Author(s)
  Masaki Fukuyo, Toshiaki Nakano, Kenji K. Kojima, Yingbiao Zhang, Yoshikazu Furuta, Ken Ishikawa, Miki Watanabe-Matsui, Hirokazu Yano, Takeshi Hamakawa, Hiroshi Ide and Ichizo Kobayashi
- Organizer
  日本進化学会第17回大会
- Place of Presentation
  中央大学後楽園キャンパス（東京都文京区）
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PROJECT-15K14572
[Presentation] Network of DNA methyltransferase behind the adaptive phenotype in Helicobacteri pylori2015
- Author(s)
  Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Yoshikazu Furuta, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  Gordon Research Seminar, Microbial Population Biology
- Place of Presentation
  Andover, NH, USA
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] Methylome Diversification in Human Gastric Pathogen Helicobacter pylori2015
- Author(s)
  Hirokazu Yano, Zobaidul M. Alam, Yoshikazu Furuta, Emiko Rimbara, Hiroe Namba-Fukuyo, Tomoko Shibata, Tomoaki Nishiyama, Shuji Shigenobu, Mitsuyasu Hasebe, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  42nd IMSUT Founding Commemorative Symposium (医科研創立記念シンポジウム)
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-06-01
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] ピロリ菌の適応形質を支配するDNAメチル化系ネットワークの発見2015
- Author(s)
  矢野大和、Zobaidul M. Alam、林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本進化学会第１７回大会
- Place of Presentation
  中央大学後楽園キャンパス
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] 特定のエピゲノム状態がピロリ菌ストレス耐性を支配する2015
- Author(s)
  矢野大和、Zobaidu M. Alam、林原絵美子、古田芳一、鈴木穰、菅野純夫、柴山恵吾、小林一三
- Organizer
  第21回ヘリコバクター学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] 特定のエピゲノム状態がピロリ菌ストレス耐性を支配する2015
- Author(s)
  矢野大和
- Organizer
  第21回日本ヘリコバクター学会学術集会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Network of DNA methyltransferase behind the adaptive phenotype in Helicobacteri pylori.2015
- Author(s)
  Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Yoshikazu Furuta, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  Gordon Research Conference, Microbial Population Biology
- Place of Presentation
  アンドーバー（米国）
- Year and Date
  2015-07-19
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Network of DNA methyltransferase behind the adaptive phenotype in Helicobacteri pylori2015
- Author(s)
  Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Yoshikazu Furuta, Yutaka Suzuki, Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  Gordon Research Conference, Microbial Population Biology
- Place of Presentation
  Andover, NH, USA
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18665
[Presentation] Plasmid-host adapatation through fitness cost ameriolation of a plasmid replication protein2014
- Author(s)
  Hirokazu Yano, Ktarznya Wegrzyn, Wesley Loftie-Eaton, Igor Konieczny, Eva M. Top
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] Diverse broad-host-range plasmids from freshwater carry few accessory genes2014
- Author(s)
  Celeste Brown, Diya Sen, Hirokazu Yano, Matthew Bauer, Linda Rogers, Geraldine Van der Auwera, Eva Top
- Organizer
  日本ゲノム微生物学会
- Place of Presentation
  東京農業大学　世田谷キャンパス
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] 比較ゲノミクス・メチロミクス・トランスクリプトミクスでのエピゲノム駆動進化の実証
- Author(s)
  矢野大和、小林一三、福世真樹
- Organizer
  ゲノム支援拡大班会議
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2014-08-20 – 2014-08-21
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Methylome Diversification in Human Gastric Pathogen Helicobacter pylori
- Author(s)
  Yoshikazu Furuta, Hirokazu Yano, Zobaidul M. Alam, Emiko Rimbara, Hiroe Namba-Fukuyo,Tomoko Shibata, Tomoaki Nishiyama, Shuji Shigenobu, Mitsuyasu Hasebe, Yutaka Suzuki,Sumio Sugano, Keigo Shibayama, Ichizo Kobayashi
- Organizer
  International Symposium on Genome Science 2015
- Place of Presentation
  一橋ホール（東京都千代田区）
- Year and Date
  2015-01-20 – 2015-01-21
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] 複製開始タンパク質のフィットネスコストの改善を伴うプラスミドの宿主適応
- Author(s)
  矢野大和，Eva M Top
- Organizer
  ゲノム微生物学会若手の会
- Place of Presentation
  ろうきん研修所富士センター
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] 特定のエピゲノム状態がピロリ菌ストレス耐性を支配する
- Author(s)
  矢野大和、Md.Zobaidul Alam, 林原絵美子、古田芳一、鈴木穣、菅野純夫、柴山恵吾、小林一三
- Organizer
  第9回日本ゲノム微生物学会
- Place of Presentation
  神戸大学（兵庫県神戸市）
- Year and Date
  2015-03-06 – 2015-03-08
- Data Source
  KAKENHI-PROJECT-25291080
[Presentation] Diversification of host range within the IncP-1 plasmid group
- Author(s)
  Hirokazu Yano, Linda Rogers, Molly Knox, Heuer Holger, Kornelia Smalla, Celeste Brown C, and Eva Top
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際会議場神戸国際展示場
- Data Source
  KAKENHI-PROJECT-25850049
[Presentation] 特定のエピゲノム状態がピロリ菌ストレス耐性を支配する
- Author(s)
  矢野大和、Zobaidu M. Alam、林原絵美子、古田芳一、鈴木穰、菅野純夫、柴山恵吾、小林一三
- Organizer
  日本ゲノム微生物学会
- Place of Presentation
  神戸大学六甲第２キャンパス
- Year and Date
  2015-03-06 – 2015-03-08
- Data Source
  KAKENHI-PROJECT-25850049

1. Lisa Nonaka (70363265)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
2. KOBAYASHI Ichizo (30126057)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. IDE Hiroshi (30223126)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. FUKUYO Masaki (40639085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KOJIMA Kenji (90748774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. FURUTA Yoshikazu (40613667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. HASEBE Mitsuyasu (40237996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. OHTSUKI Hisashi (50517802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西内由紀子 (00333526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 岩本朋忠 (70416402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 森宙史 (40610837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Suzuki Satoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Maruyama Fumito

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. NAKANO Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 野村暢彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YANO HIROKAZU 矢野 大和

YANO Hirokazu 矢野 大和

Research Projects

Research Products

Co-Researchers

Elucidation of integration factors and maintenance mechanisms of multidrug-resistant plasmids in aquaculture environments

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実験と生物情報解析に基づくヒッチハイカー型組み込み因子群の転移機構と宿主域の解明Principal Investigator

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Pangenome-phenotype association analysis reveals niche adaptation mechanisms of slow-growing mycobacteriaPrincipal Investigator

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The effects of antibiotics to the transfer frequency of the antibiotic resistance genes and the evolution of high-level resistance.

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Addressing a model of mycobacterium evolution via sexual reproduction: approaches by molecular genetics and population genomicsPrincipal Investigator

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Transposition mechanisms of multiple drug resistance genes from plasmids to chromosome among bacteria in the aquaculture environment

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The epigenetics-driven adaptive evolution concept and its application to microbe engineeringPrincipal Investigator

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Base-excision restriction enzymes: structure, function and epigenetics

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Mobile genetic elements associated with multi-drug resistance in the bacteria from aquaculture environments

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Base excising restriction enzymes

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Mechanisms underlying target specificity changes of DNA methyltransferase, and its application to epigenome breedingPrincipal Investigator

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Adaptive evolution through digital changes in the epigenome

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[Journal Article] Mobile class A β-lactamase gene blaGMA-12024

Author(s)

Journal Title

YANO HIROKAZU 矢野大和

YANO Hirokazu 矢野大和