MASHIMA Tsukasa 真嶋司

Researcher Number	20707426
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2019: 京都大学, エネルギー理工学研究所, 助教
Review Section/Research Field	Principal Investigator Structural biochemistry / Science and Engineering Except Principal Investigator Structural biochemistry
Keywords	Principal Investigator NMR / 四重鎖核酸 / アプタマー / 立体構造 / プリオン病 / カリウムイオン / リボザイム Except Principal Investigator RNAアプタマー / プリオン病 / 相互作用 … More / ＮＭＲ / ＲＮＡアプタマー / プリオンタンパク質 / 分子認識 / 抗プリオン活性 / アミロイドβタンパク質 / 分子間相互作用 / 線維化 / アルツハイマー病 / 機能性ＲＮＡ / プリオン / アミロイドβ / NMR / 機能性核酸 / プリオン蛋白質 / Ab蛋白質 / アプタマー / ４重鎖 / リボザイム / In cell NMR / Tatタンパク質 / 4重鎖 / 立体構造 / Ｉｎ　ｃｅｌｌ　ＮＭＲ / カリウムイオン / RNA酵素 Less

Molecular design of quadruplex-forming nculeic acids that inhibit the pathological conformational conversion of PrP and elucidation of its inhibitory mechanismPrincipal Investigator
- Principal Investigator
  
  Mashima Tsukasa
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
細胞内外で活性を切り替える機能性核酸の創製Principal Investigator
- Principal Investigator
  
  真嶋司
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Screening of quadruplex-forming anti-prion nucleic acids and molecular design on the basis of its mechanismPrincipal Investigator
- Principal Investigator
  
  Mashima Tsukasa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Development of intelligent ribozyme and aptamer whose activities switch on in response to environment
- Principal Investigator
  
  Katahira Masato
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Structural basis of prevention by RNA aptamer of transformation of prion protein and its interaction with Ab
- Principal Investigator
  
  Katahira Masato
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Encyclopedia of Biophysics, Introduction to Nucleic Acids NMR2013
- Author(s)
  Katahira, M. and Mashima, T.
- Total Pages
  10
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25291013
[Journal Article] Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein2020
- Author(s)
  Mashima Tsukasa、Lee Joon-Hwa、Kamatari Yuji O.、Hayashi Tomohiko、Nagata Takashi、Nishikawa Fumiko、Nishikawa Satoshi、Kinoshita Masahiro、Kuwata Kazuo、Katahira Masato
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 4934-4934
- DOI
  10.1038/s41598-020-61966-4
- NAID
  120006813315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K14674, KAKENHI-PUBLICLY-18H04550, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-16K07269, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-20K21477, KAKENHI-PROJECT-18K19397
[Journal Article] RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS2020
- Author(s)
  Hamad Nesreen、Mashima Tsukasa、Yamaoki Yudai、Kondo Keiko、Yoneda Ryoma、Oyoshi Takanori、Kurokawa Riki、Nagata Takashi、Katahira Masato
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 2629-2629
- DOI
  10.1038/s41598-020-59496-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18065, KAKENHI-PUBLICLY-18H04550, KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-17K05930, KAKENHI-PROJECT-18K14636, KAKENHI-PROJECT-19K16054, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-17K14515, KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-18K19397
[Journal Article] The anti‐prion RNA aptamer R12 disrupts the Alzheimer's disease‐related complex between prion and amyloid β2019
- Author(s)
  Iida Mamiko、Mashima Tsukasa、Yamaoki Yudai、So Masatomo、Nagata Takashi、Katahira Masato
- Journal Title
  
  The FEBS Journal
  
  Volume: 印刷中 Issue: 12 Pages: 2355-2365
- DOI
  10.1111/febs.14819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-17K14515, KAKENHI-PROJECT-18K19397
[Journal Article] Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA2018
- Author(s)
  Kondo Keiko、Mashima Tsukasa、Oyoshi Takanori、Yagi Ryota、Kurokawa Riki、Kobayashi Naohiro、Nagata Takashi、Katahira Masato
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2864-2864
- DOI
  10.1038/s41598-018-21142-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-17K05930, KAKENHI-PROJECT-17K07307, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-26440026, KAKENHI-PROJECT-15K18485
[Journal Article] Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis2018
- Author(s)
  Ohara Yukiko、Ozeki Yuriko、Tateishi Yoshitaka、Mashima Tsukasa、Arisaka Fumio、Tsunaka Yasuo、Fujiwara Yoshie、Nishiyama Akihito、Yoshida Yutaka、Kitadokoro Kengo、Kobayashi Haruka、Kaneko Yukihiro、Nakagawa Ichiro、Maekura Ryoji、Yamamoto Saburo、Katahira Masato、Matsumoto Sohkichi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 10 Pages: 0204160-0204160
- DOI
  10.1371/journal.pone.0204160
- NAID
  120006534592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-18K08172, KAKENHI-PROJECT-16H05187, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16K14048, KAKENHI-PROJECT-17K19552
[Journal Article] DNA G-wire formation using an artificial peptide is controlled by protease activity2017
- Author(s)
  Usui, K., Okada, A., Sakashita, S., Shimooka, M., Tsuruoka, T., Nakano, S., Miyoshi, D., Mashima, T., Katahira, M., Hamada, Y.
- Journal Title
  
  Molecules
  
  Volume: 22 Issue: 11 Pages: 1991-1991
- DOI
  10.3390/molecules22111991
- NAID
  120006501324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PLANNED-17H06351, KAKENHI-PROJECT-15H03840, KAKENHI-PROJECT-26460163, KAKENHI-PROJECT-16K14042
[Journal Article] Development of an RNA aptamer that acquires binding capacity against HIV-1 Tat protein via G-quadruplex formation in response to potassium ions2017
- Author(s)
  Yamaoki, Y., Nagata, T., Mashima, T., Katahira, M.
- Journal Title
  
  Chemical communications
  
  Volume: 53 Issue: 52 Pages: 7056-7059
- DOI
  10.1039/c7cc03312e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-17K14515, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-26440026, KAKENHI-PROJECT-16K14678
[Journal Article] The binding specificity of translocated in liposarcoma/fused in sarcoma with lncRNA transcribed from the promoter region of cyclin D12016
- Author(s)
  Yoneda, R., Suzuki, S., Mashima, T., Kondo, K., Nagata, T., Katahira, M. and Kurokawa, R.
- Journal Title
  
  Cell Biosci.
  
  Volume: 6(4) Issue: 1 Pages: 1-12
- DOI
  10.1186/s13578-016-0068-8
- NAID
  120005763383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440026, KAKENHI-PROJECT-15K18485, KAKENHI-PUBLICLY-15H00813, KAKENHI-PUBLICLY-15H01634, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-25293073, KAKENHI-PUBLICLY-16H00833
[Journal Article] Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA2016
- Author(s)
  Masuda, K., Ripley, B., Nyati, K., Dubey, P., Zaman, M., Hanieh, H., Hoga, M., Yamashita, K., Standley, D., Mashima, T., Katahira, M., Okamoto, T., Matsuura, Y., Takeuchi, O. and Kishimoto, T.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 213 Issue: 4 Pages: 605-619
- DOI
  10.1084/jem.20151289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00813, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-26860328, KAKENHI-PROJECT-15H04736
[Journal Article] Bifacial Base-Pairing Behaviors of 5-Hydroxyuracil DNA Bases Both through Hydrogen Bonding and Metal Coordination2015
- Author(s)
  Takezawa, Y., Nishiyama K., Mashima T., Katahira, M. and Shionoya, M.
- Journal Title
  
  Chemistry
  
  Volume: 21 Issue: 42 Pages: 14713-14716
- DOI
  10.1002/chem.201502772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00813, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-25291013, KAKENHI-PROJECT-26248016
[Journal Article] Crosslinking reactions of 4-amino-6-oxo-2-vinylpyrimidine with guanine derivatives and structural analysis of the adducts2015
- Author(s)
  S.Kusano, S. Ishiyama,Sik Lok Lam, T. Mashima, M. Katahira, K. Miyamoto, M. Aida, F. Nagatsugi
- Journal Title
  
  Nucl.Acids Res
  
  Volume: 43 Issue: 16 Pages: 7717-7730
- DOI
  10.1093/nar/gkv797
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14975, KAKENHI-PUBLICLY-15H00813, KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PUBLICLY-26102733, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-25288073, KAKENHI-PROJECT-25291013
[Journal Article] K+-responsive off-to-on switching of hammerhead ribozyme through dual G-quadruplex formation requiring no heating and cooling treatment2015
- Author(s)
  Yamaoki Y, Nagata T, Mashima T, Katahira M
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 468(1-2) Issue: 1-2 Pages: 27-31
- DOI
  10.1016/j.bbrc.2015.10.173
- NAID
  120005712951
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440026, KAKENHI-PUBLICLY-15H00813, KAKENHI-PUBLICLY-15H01634, KAKENHI-PROJECT-26650014, KAKENHI-PROJECT-26840020
[Journal Article] Boosting of activity enhancement of K+-responsive quadruplex hammerhead ribozyme2015
- Author(s)
  Yudai Yamaoki, Tsukasa Mashima, Takashi Nagata and Masato Katahira
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 27 Pages: 5898-5901
- DOI
  10.1039/c5cc00961h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J00927, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-25291013, KAKENHI-PROJECT-26440026, KAKENHI-PROJECT-26650014, KAKENHI-PROJECT-26840020, KAKENHI-PUBLICLY-26104520
[Journal Article] Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition2014
- Author(s)
  T. Hayashi, H. Oshima, T. Mashima, T. Nagata, M. Katahira, M. Kinoshita
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 42 Issue: 11 Pages: 6861-6875
- DOI
  10.1093/nar/gku382
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J03866, KAKENHI-ORGANIZER-20118001, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-25291013, KAKENHI-PROJECT-25291035, KAKENHI-PROJECT-26840020
[Journal Article] Anti-prion activity of an RNA aptamer and its structural basis2013
- Author(s)
  Mashima, T., Nishikawa, F., Kamatari Y. O., Fujiwara, H., Saimura, M., Nagata, T., Kodaki, T., Nishikawa, S., Kuwata, K., Katahira, M.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 41 Issue: 2 Pages: 1355-1362
- DOI
  10.1093/nar/gks1132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02435, KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-23657072, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-25291013, KAKENHI-PUBLICLY-24113710, KAKENHI-PUBLICLY-24121714
[Presentation] プリオンタンパク質の構造変換を抑制するRNAアプタマーの開発と構造決定2019
- Author(s)
  真嶋司、Lee, Joon-Hwa、鎌足雄司、林智彦、永田崇、西川富美子、西川諭、木下正弘、桑田一夫、片平正人
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Development of anti-prion RNA aptamers and destruction of the Alzheimer's disease-related complex2019
- Author(s)
  Mashima, T., Iida, M., Lee, J., Yamaoki, Y., So, M., Kamatari, Y. O., Hayashi, T., Kinoshita, M., Kuwata, K., Nagata, T. and Katahira, M.
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Disruption of the Alzheimer’s disease-related complex between prion and amyloid β by an anti-prion aptamer2019
- Author(s)
  Mashima, T., Iida, M., Yamaoki, Y., So, M., Nagata, T. and Katahira, M.
- Organizer
  Commemorative International Symposium of Nucleic Acid Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] 非常に高い活性を有する抗プリオンRNAアプタマーの構造機能相関2019
- Author(s)
  真嶋司、Lee, Joon-Hwa、鎌足雄司、林智彦、木下正弘、桑田一夫、永田崇、片平正人
- Organizer
  第58回NMR討論会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] An RNA aptamer disrupts the interaction of prion protein with Amyloid β2018
- Author(s)
  Iida, M., Mashima, T., Yamaoki, Y., So, M., Nagata, T. and Katahira, M.
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Development of RNA Aptamer That Has High Anti-prion Activity and Its Structural Basis2018
- Author(s)
  Mashima, T., Lee, J., Kamatari, Y. O., Hayashi, T., Nishikawa, F., Nagata, T., Nishikawa, S., Kinoshita, M., Kuwata, K. and Katahira, M.
- Organizer
  The 45th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] 抗プリオン活性を有する四重鎖RNAの構造決定と高い活性の発現機構の解明2018
- Author(s)
  真嶋司、Lee Joon-Hwa、鎌足雄司、林智彦、西川富美子、永田崇、西川諭、木下正弘、桑田一夫、片平正人
- Organizer
  第57回NMR討論会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] TLS/FUS の非コード RNA の認識機構の構造学的研究2017
- Author(s)
  真嶋司，小澤駿介, N. Hamad, 米田竜馬, 黒川理樹，永田崇，片平正人
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Invention of RNA aptamer and ribozyme whose activities switch on in response to potassium ion via G-quadruplex formation2017
- Author(s)
  Yamaoki, Y., Mashima, T., Nagata, T. Katahira, M.
- Organizer
  6th International Meeting on Quadruplex Nucleic Acids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] プリオンアプタマーはアルツハイマー病に関与するプリオン蛋白質と Aβ オリゴマーの複合体の形成を阻害する2017
- Author(s)
  飯田真美子, 真嶋司, 山置佑大, 永田崇, 片平正人
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] テロメア長短縮をもたらすTLS/FUS蛋白質とテロメアDNAおよびTERRAのグアニン四重鎖との複合体に関するNMR解析2017
- Author(s)
  近藤敬子, 真嶋司, 大吉崇文, 黒川理樹, 小林直宏, 永田崇, 片平正人
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] The effect of different target nucleic acids on the structural change of TLS2017
- Author(s)
  Hamad, N., Mashima, T., Watanabe, H., Uchihashi, T., Kurokawa, R., Nagata, T. Katahira, M.
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Interaction between non-coding RNA and TLS/FUS protein, and structural change2017
- Author(s)
  Mashima, T., Nagata, T., Hamad, N., Ozawa, S., Yamaoki, Y., Kondo, K., Watanabe, H., Yoneda, R., Uchihashi, T., Kurokawa, R. Katahira, M.
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Conformational change detection of translocated in liposarcoma, TLS, upon binding to various RNAs2017
- Author(s)
  Hamad, N., Mashima, T., Yamaoki, Y., Kondo, K., Kurokawa, R., Nagata, T. Katahira, M.
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] 非コードRNAとTLS/FUSタンパク質の相互作用様式と結合に伴うTLS/FUSの大きな構造変化2017
- Author(s)
  真嶋司，ハマッドネスリン，小澤駿介，渡辺大輝，内橋貴之，米田竜馬，黒川理樹，永田崇，片平正人
- Organizer
  第56回NMR討論会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] TLS/FUS のRNA認識機構と結合に伴うコンフォメーション変化の研究2017
- Author(s)
  真嶋司，小澤駿介, N. Hamad, 米田竜馬, 黒川理樹，永田崇，片平正人
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] NMR analysis of the recognition of non-coding RNA and DNA by TLS/FUS which causes transcriptional repression of cyclin D1 1 and telomere shorteningThe 21st Annual Meeting of the RNA Society2016
- Author(s)
  T. Mashima. K. Kondo, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] Non-coding RNA/DNA recognition by TLS/FUS that causes repression of cyclin D1 transcription and telomere elongation2016
- Author(s)
  K. Kondo, T. Mashima, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The 43rd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  熊本大学、熊本県
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] K+-responsive activation of ribozyme system via structural transition from duplex to dual-quadruplex requiting no heating and cooling treatment2016
- Author(s)
  Y. Yamaoki, T. Mashima, T. Nagata, M. Katahira
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] K+-responsive activation of ribozyme system via structural transition from duplex to dual-quadruplex requiting no heating and cooling treatment2016
- Author(s)
  Y. Yamaoki, T. Mashima, T. Nagata, M. Katahira
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会館、京都府
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] NMR analysis of the recognition of non-coding RNA and DNA by TLS/FUS which causes transcriptional repression of cyclin D1 1 and telomere shorteningThe 21st Annual Meeting of the RNA Society2016
- Author(s)
  T. Mashima. K. Kondo, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Non-coding RNA/DNA recognition by TLS/FUS that causes repression of cyclin D1 transcription and telomere elongation2016
- Author(s)
  K. Kondo, T. Mashima, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The 43rd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  熊本大学、熊本県
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] Cyclin D1転写抑制を担う TLS/FUS タンパク質と非コードRNA の相互作用の NMR 法による解析2016
- Author(s)
  真嶋司, 小澤駿介, 近藤敬子, 永田崇, 黒川理樹, 片平正人
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] カリウムイオン応答性Tat結合RNAアプタマーおよびハンマーヘッドリボザイムの創製および in-cell NMR法による細胞内核酸の観測2016
- Author(s)
  山置佑大, 清石彩華, 真嶋司, 加納ふみ, 村田昌之, 永田崇, 片平正人
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  県立音楽堂、石川県
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] プリオン蛋白質とそれを標的とする RNA 分子の Aβ線維化への影響2016
- Author(s)
  飯田真美子, 真嶋司, 山置佑大, 永田崇, 片平正人
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] プリオンタンパク質とプリオンタンパク質を標的とする RNA 分子の Aβ線維化への影響2016
- Author(s)
  M. Iida, T. Mashima, Y. Yamaoki, T. Nagata
- Organizer
  生物物理学会第54回年会
- Place of Presentation
  つくば国際会議場、茨城県
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Cyclin D1転写抑制を担う TLS/FUS タンパク質と非コードRNA の相互作用の NMR 法による解析2016
- Author(s)
  真嶋司, 小澤駿介, 近藤敬子, 永田崇, 黒川理樹, 片平正人
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] Cyclin D1遺伝子転写抑制やテロメア長制御に関わる TLS/FUS タンパク質と非コード核酸間の相互作用のＮＭＲ法による解析2016
- Author(s)
  近藤敬子, 真嶋司, 大吉崇文, 米田竜馬, 黒川理樹, 永田崇, 片平正人
- Organizer
  第55回NMR討論会
- Place of Presentation
  広島国際会議場、広島県
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] 三者複合体形成によってテロメア短縮をもたらすTLS/FUSのテロメアDNAおよびTERRA認識機構に関するNMR解析2016
- Author(s)
  近藤敬子, 真嶋司, 大吉崇文, 永田崇, 片平正人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] C:G塩基対を選択的に認識する人工塩基を含む三重鎖DNAの構造解析2016
- Author(s)
  真嶋司、岡村秀紀、王磊、谷口陽祐、佐々木茂貴、片平正人
- Organizer
  第55回NMR討論会
- Place of Presentation
  広島国際会議場、広島県
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] カリウムイオン応答性Tat結合RNAアプタマーおよびハンマーヘッドリボザイムの創製および in-cell NMR法による細胞内核酸の観測2016
- Author(s)
  山置佑大, 清石彩華, 真嶋司, 加納ふみ, 村田昌之, 永田崇, 片平正人
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  県立音楽堂、石川県
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] 非コードRNAと結合してcyclin D1転写を抑制するTLS/FUSのRNA認識機構の構造学的基盤2016
- Author(s)
  真嶋司, 小澤駿介, 近藤敬子, Nesreen Hamad, 米田竜馬, 黒川理樹, 永田崇, 片平正人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] NMR studies of non-coding RNA and DNA recognition by TLS/FUS which induces transcriptional repression of cyclin D1 and telomere shortening2016
- Author(s)
  K. Kondo, T. Mashima, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] 三者複合体形成によってテロメア短縮をもたらすTLS/FUSのテロメアDNAおよびTERRA認識機構に関するNMR解析2016
- Author(s)
  近藤敬子, 真嶋司, 大吉崇文, 永田崇, 片平正人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] プリオン蛋白質とそれを標的とする RNA 分子の Aβ線維化への影響2016
- Author(s)
  飯田真美子, 真嶋司, 山置佑大, 永田崇, 片平正人
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] プリオンタンパク質とプリオンタンパク質を標的とする RNA 分子の Aβ線維化への影響2016
- Author(s)
  M. Iida, T. Mashima, Y. Yamaoki, T. Nagata, M. Katahira
- Organizer
  生物物理学会第54回年会
- Place of Presentation
  生物物理学会第54回年会
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] リグノセルロースバイオリファイナリーのためのリグニン・ペプチド間相互作用解析2016
- Author(s)
  山口亜佐子，末富高志，大城理志，徳永有希，西村裕司，永田崇，真嶋司，片平正人，礒﨑勝弘，高谷光，中村正治，渡辺隆司
- Organizer
  第61回リグニン討論会
- Place of Presentation
  京都大学、京都府
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] プリオン蛋白質とそれを標的とするRNA分子のAβ;繊維化への影響2016
- Author(s)
  飯田真美子、真嶋司、山置佑大、永田崇、片平正人
- Organizer
  第１６回日本蛋白質科学会
- Place of Presentation
  福岡国際会議所（福岡市）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-25291013
[Presentation] 非コードRNAと結合してcyclin D1転写を抑制するTLS/FUSのRNA認識機構の構造学的基盤2016
- Author(s)
  真嶋司, 小澤駿介, 近藤敬子, Nesreen Hamad, 米田竜馬, 黒川理樹, 永田崇, 片平正人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] Cyclin D1遺伝子転写抑制やテロメア長制御に関わる TLS/FUS タンパク質と非コード核酸間の相互作用のNMR法による解析2016
- Author(s)
  近藤敬子, 真嶋司, 大吉崇文, 米田竜馬, 黒川理樹, 永田崇, 片平正人
- Organizer
  第55回NMR討論会
- Place of Presentation
  広島国際会議場、広島県
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] K+-responsive activation of dual-quadruplex forming ribozyme system requiring no heating and cooling treatment2016
- Author(s)
  Y. Yamaoki, T. Mashima, T. Nagata, M. Katahira
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] K+-responsive activation of dual-quadruplex forming ribozyme system requiring no heating and cooling treatment2016
- Author(s)
  Y. Yamaoki, T. Mashima, T. Nagata, M. Katahira
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] リグノセルロースバイオリファイナリーのためのリグニン・ペプチド間相互作用解析2016
- Author(s)
  山口亜佐子，末富高志，大城理志，徳永有希，西村裕司，永田崇，真嶋司，片平正人，礒﨑勝弘，高谷光，中村正治，渡辺隆司
- Organizer
  第61回リグニン討論会
- Place of Presentation
  京都大学、京都府
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] NMR studies of non-coding RNA and DNA recognition by TLS/FUS which induces transcriptional repression of cyclin D1 and telomere shortening2016
- Author(s)
  K. Kondo, T. Mashima, T. Oyoshi, R. Yoneda, R. Kurokawa, T. Nagata, M. Katahira
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  京都国際会館、京都府
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] C:G塩基対を選択的に認識する人工塩基を含む三重鎖DNAの構造解析2016
- Author(s)
  真嶋司、岡村秀紀、王磊、谷口陽祐、佐々木茂貴、片平正人
- Organizer
  第55回NMR討論会
- Place of Presentation
  広島国際会議場、広島県
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-16K07269
[Presentation] NMR study of the recognition of non-coding RNA and DNA by TLS/FUS, a key regulator of cyclin D12015
- Author(s)
  Kondo, K., Mashima, T., Oyoshi, T., Kurokawa, R., Nagata, T. and Katahira, M.
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Egret Himeji, Himeji-shi, Hyogo
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] 転写抑制やテロメア短縮を引き起こすTLS/FUSと長鎖非コードRNAおよびDNAとの結合の構造基盤2015
- Author(s)
  近藤敬子、真嶋司、大吉崇文、黒川理樹、永田崇、片平正人
- Organizer
  第17回RNAミーティング
- Place of Presentation
  ホテルライフォート札幌, 北海道札幌市
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] 異常型プリオン蛋白質の産生を抑制する四重鎖核酸の構造解析2015
- Author(s)
  真嶋司、西川富美子、鎌足雄司、永田崇、西川諭、桑田一夫、片平正人
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学工学部, 熊本県熊本市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] 転写抑制やテロメア短縮を引き起こすTLS/FUSと長鎖非コードRNAおよびDNAとの結合の構造基盤2015
- Author(s)
  近藤敬子、真嶋司、大吉崇文、黒川理樹、永田崇、片平正人
- Organizer
  第17回RNAミーティング
- Place of Presentation
  ホテルライフォート札幌, 北海道札幌市
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
- Author(s)
  Nagatsugi, F., Kusano, S., Ishiyama, S., Lam, S. L., Mashima, T. and Katahira, M.
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Egret Himeji, Himeji-shi, Hyogo
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] NMR study of the recognition of non-coding RNA and DNA by TLS/FUS, a key regulator of cyclin D12015
- Author(s)
  Kondo, K., Mashima, T., Oyoshi, T., Kurokawa, R., Nagata, T. and Katahira, M.
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Egret Himeji, Himeji-shi, Hyogo
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] カリウムイオンを認識して活性がスイッチングするTat結合RNAアプタマーおよびハンマーヘッドリボザイムの創製2015
- Author(s)
  山置佑大、真嶋司、永田崇、片平正人
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学工学部, 熊本県熊本市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] カリウムイオンを認識して活性がスイッチングするTat結合RNAアプタマーおよびハンマーヘッドリボザイムの創製2015
- Author(s)
  山置佑大、真嶋司、永田崇、片平正人
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学工学部, 熊本県熊本市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] 異常型プリオン蛋白質の産生を抑制する四重鎖核酸の構造解析2015
- Author(s)
  真嶋司、西川富美子、鎌足雄司、永田崇、西川諭、桑田一夫、片平正人
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学工学部, 熊本県熊本市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
- Author(s)
  Nagatsugi, F., Kusano, S., Ishiyama, S., Lam, S. L., Mashima, T. and Katahira, M.
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Egret Himeji, Himeji-shi, Hyogo
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00813
[Presentation] 異常型プリオン蛋白質の産生を抑制する四重鎖核酸の構造解析2015
- Author(s)
  真嶋司，西川富美子，鎌足雄司，永田崇，西川諭，桑田一夫，片平正人
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学（熊本市）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25291013
[Presentation] Origin of the anti-prion activity of quadruplex2013
- Author(s)
  Tsukasa Mashima, Fumiko Nishikawa, Yuji O. Kamatari, Masayuki Saimura, Takashi Nagata, Satoshi Nishikawa, Kazuo Kuwata, Masato Katahira
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry 2013
- Place of Presentation
  神奈川大学(横浜市）
- Data Source
  KAKENHI-PROJECT-25291013
[Presentation] Creation of novel Tat-binding aptamer and ribozyme whose activities switch on in response to K+ via quadruplex formation
- Author(s)
  Yamaoki, Y., Mashima, T., Nagata, T. and Katahira, M.
- Organizer
  The 41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kitakyushu International Conference Center, Kitakyushu-shi, Fukuoka
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] CCND1転写抑制とテロメア短縮に関与する天然変性蛋白質TLS/FUSによる非コードRNAとDNAの認識機構のNMR法による解明
- Author(s)
  近藤敬子、真嶋司、大吉崇文、黒川理樹、永田崇、片平正人
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  神奈川県横浜市、ワークピア横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] CCND1転写抑制とテロメア短縮をもたらすTLS/FUSによる非コードRNAとDNA認識機構のNMR法による解明
- Author(s)
  近藤敬子、真嶋司、大吉崇文、黒川理樹、永田崇、片平正人
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市、パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] Screening for novel aptamer against prion protein and its structural study
- Author(s)
  真嶋司、西川富美子、鎌足雄司、永田崇、西川諭、桑田一夫、片平正人
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  北海道札幌市、札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] カリウムイオンを感知して自らの活性をスイッチングするTat捕捉アプタマーおよびリボザイムの創製
- Author(s)
  山置佑大、真嶋司、永田崇、片平正人
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  愛知県名古屋市、ウインクあいち
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] Development of Tat-binding aptamer and ribozyme which switch their activities in response to K+
- Author(s)
  山置佑大、真嶋司、永田崇、片平正人
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  北海道札幌市、札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] Real-time NMR monitoring of enzymatic reaction of anti-HIV protein, structure of anti-prion RNA aptamer and wood biomass analysis
- Author(s)
  Kanba, K., Mashima, T., Okamura, H., Furukawa, A., Sugase, K., Nishimura, H., Watanabe, T., Nagata, T., and Katahira, M.
- Organizer
  The 5th Japan-Taiwan NMR symposium
- Place of Presentation
  Hokkaido University, Hokkaido
- Year and Date
  2014-09-29 – 2014-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-26840020
[Presentation] The deamination of APOBEC3G is controlled by the sliding-direction-dependent catalytic activity, and anti-prion activity of an RNA aptamer and its structual basis
- Author(s)
  Ayako Furukawa, Kenji Sugase, Ryo Morishita, Takashi Nagata, Akifumi Takaori-Kondo, Akihide Ryo, Tsukasa Mashima, Fomiko Nishikawa, Satoshi Nishikawa, Yuji Kamatari, Kazuo Kuwata, Masato Katahira
- Organizer
  The 10th Korea-Japan Bilateral Symposium on Biological NMR
- Place of Presentation
  ソウル大学(ソウル、韓国）
- Invited
- Data Source
  KAKENHI-PROJECT-25291013

1. Katahira Masato (70211844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. NAGATA Takashi (10415250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. YAMAOKI Yuudai (00778095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 林智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 米田竜馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 高橋栄夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 永次史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MASHIMA Tsukasa 真嶋 司

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Molecular design of quadruplex-forming nculeic acids that inhibit the pathological conformational conversion of PrP and elucidation of its inhibitory mechanismPrincipal Investigator

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細胞内外で活性を切り替える機能性核酸の創製Principal Investigator

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Screening of quadruplex-forming anti-prion nucleic acids and molecular design on the basis of its mechanismPrincipal Investigator

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Development of intelligent ribozyme and aptamer whose activities switch on in response to environment

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Structural basis of prevention by RNA aptamer of transformation of prion protein and its interaction with Ab

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[Book] Encyclopedia of Biophysics, Introduction to Nucleic Acids NMR2013

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[Journal Article] Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein2020

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[Journal Article] RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS2020

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[Journal Article] The anti‐prion RNA aptamer R12 disrupts the Alzheimer's disease‐related complex between prion and amyloid β2019

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[Journal Article] Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA2018

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[Journal Article] Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis2018

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[Journal Article] DNA G-wire formation using an artificial peptide is controlled by protease activity2017

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[Journal Article] Development of an RNA aptamer that acquires binding capacity against HIV-1 Tat protein via G-quadruplex formation in response to potassium ions2017

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[Journal Article] The binding specificity of translocated in liposarcoma/fused in sarcoma with lncRNA transcribed from the promoter region of cyclin D12016

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MASHIMA Tsukasa 真嶋司