Tsukakoshi Kaori 塚越かおり

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TSUKAKOSHI Kaori 塚越かおり

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Researcher Number	20708474
Other IDs
Affiliation (Current)	2025: 東京理科大学, 理学部第一部化学科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京農工大学, 工学(系)研究科(研究院), 助教 2015 – 2017: 東京農工大学, 工学(系)研究科(研究院), 助教 2013 – 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (II) / Basic Section 37010:Bio-related chemistry / Biological pharmacy / Biofunction/Bioprocess Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator アプタマー / アルツハイマー病 / 脳内ホメオスタシス / タンパク質間相互作用 / 酵素活性 / 神経炎症 / アミロイド / 脳ホメオスタシス / オリゴマー / アミロイドβ … More / タンパク質制御 / タンパク質操作 / プリオンタンパク質 / プロテアーゼ / 凝集 / トランスレーショナルリサーチ / バイオマーカー / 早期診断 … More Except Principal Investigator 遺伝子改変 / 人工抗体 / がん転移 / マトリックス分解酵素 / MMP / コラゲナーゼ / 癌転移 Less

Creation of aptameric biologyArea Organizer
- Area Organizer
  
  塚越かおり
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
アプタマー生物学の創成による脳内恒常性維持機構の解明Principal Investigator
- Principal Investigator
  
  塚越かおり
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tokyo University of Agriculture and Technology
活性増強アプタマーを用いた脳内恒常性維持機構制御マウスの開発Principal Investigator
- Principal Investigator
  
  塚越かおり
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tokyo University of Agriculture and Technology
Analysis of neurodegenerative mechanisms based on the development of beta amyloid oligomer-selective proteasesPrincipal Investigator
- Principal Investigator
  
  Tsukakoshi Kaori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Investigation of collagenolytic metabolisms in bone metastatic cancer migration and invasion for the novel drug development
- Principal Investigator
  
  Inada Masaki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo University of Agriculture and Technology
Investigation of amyloid beta oligomerization process via aggregation and disaggregationPrincipal Investigator
- Principal Investigator
  
  Tsukakoshi Kaori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Agriculture and Technology
Identification of surrogate plasma markers for early diagnosis of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TSUKAKOSHI Kaori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Aptamer-enhanced particle aggregation inhibition assay for simple homogeneous protein detection using DNA aptamer and thermo-responsive magnetic nanoparticles.2024
- Author(s)
  Rokutani S, Hiraka K, Saitoh H, Saito T, Nonaka Y, Ueno K, Tsukakoshi K, Ohnishi N, Ikebukuro K.
- Journal Title
  
  Biosens Bioelectron.
  
  Volume: 245 Pages: 115827-115827
- DOI
  10.1016/j.bios.2023.115827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22H05035, KAKENHI-PLANNED-22H05038
[Journal Article] Exploration and Application of DNA-Binding Proteins to Make a Versatile DNA-Protein Covalent-Linking Patch (D-Pclip): The Case of a Biosensing Element2024
- Author(s)
  Komiya E., Takamatsu S., Miura D., Tsukakoshi K., Tsugawa W., Sode K., Ikebukuro K. Asano R.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 146 Issue: 6 Pages: 4087-4097
- DOI
  10.1021/jacs.3c12668
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18321, KAKENHI-ORGANIZER-22H05035, KAKENHI-PLANNED-22H05038
[Journal Article] Development of a liquid chromatography-based versatile bioanalysis for bevacizumab based on pretreatment combining aptamer affinity purification and centrifugal ultrafiltration concentration2023
- Author(s)
  Todoroki Kenichiro、Hamada Daichi、Yamada Tomohiro、Saito Taro、Shimizu Yutaka、Sugiyama Eiji、Mizuno Hajime、Hayashi Hideki、Tsukakoshi Kaori、Ikebukuro Kazunori
- Journal Title
  
  Analytical Sciences
  
  Volume: 39 Issue: 11 Pages: 1805-1811
- DOI
  10.1007/s44211-023-00417-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06550, KAKENHI-ORGANIZER-22H05035, KAKENHI-PLANNED-22H05038
[Journal Article] Identification of novel amyloidosis in dogs: α-S1-casein acquires amyloidogenicity in mammary tumor by overexpression and N-terminal truncation2023
- Author(s)
  Murakami Tomoaki、Kaku Toshisuke、Tsukakoshi Kaori、Iwaide Susumu、Itoh Yoshiyuki、Hisada Miki、Nomura Kohji、Kubo Rikako、Ikebukuro Kazunori、Sassa-O’Brien Yukiko、Kametani Fuyuki
- Journal Title
  
  Veterinary Pathology
  
  Volume: 60 Issue: 2 Pages: 203-213
- DOI
  10.1177/03009858221148511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19242, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Real-time monitoring of the amyloid β1-42 monomer-to-oligomer channel transition using a lipid bilayer system2023
- Author(s)
  Numaguchi Yuri、Tsukakoshi Kaori、Takeuchi Nanami、Suzuki Yuki、Ikebukuro Kazunori、Kawano Ryuji
- Journal Title
  
  PNAS Nexus
  
  Volume: 3 Issue: 1
- DOI
  10.1093/pnasnexus/pgad437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17860, KAKENHI-PROJECT-22KJ1231, KAKENHI-PLANNED-21H05229, KAKENHI-PUBLICLY-23H04416, KAKENHI-ORGANIZER-22H05035, KAKENHI-PLANNED-22H05038, KAKENHI-PROJECT-23K24937
[Journal Article] The state of water molecules induces changes in the topologies and interactions of G-quadruplex DNA aptamers in hydrated ionic liquid2022
- Author(s)
  Fujita Kyoko、Honda Takuya、Tsukakoshi Kaori、Ohno Hiroyuki、Ikebukuro Kazunori
- Journal Title
  
  Journal of Molecular Liquids
  
  Volume: 366 Pages: 120175-120175
- DOI
  10.1016/j.molliq.2022.120175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05221, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PUBLICLY-22H04561, KAKENHI-PLANNED-22H05038
[Journal Article] CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands2022
- Author(s)
  Daiki Oshikawa, Shintaro Inaba, Yudai Kitagawa, Kaori Tsukakoshi, Kazunori Ikebukuro
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 (12) Issue: 12 Pages: 6467-6467
- DOI
  10.3390/ijms23126467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Development of a Lateral Flow Assay for Bevacizumab Using an Anti-Idiotype DNA Aptamer as a Capture Molecule2022
- Author(s)
  TODOROKI Kenichiro、ISOBE Ryota、YAMADA Tomohiro、SAITO Taro、SHIMIZU Yutaka、TSUKAKOSHI Kaori、SUGIYAMA Eiji、MIZUNO Hajime、HAYASHI Hideki、IKEBUKURO Kazunori
- Journal Title
  
  CHROMATOGRAPHY
  
  Volume: 43 Issue: 2 Pages: 73-77
- DOI
  10.15583/jpchrom.2022.008
- ISSN
  1342-8284, 1348-3315
- Year and Date
  2022-06-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03360, KAKENHI-PROJECT-22K06550, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-20K07157, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Development of Alkaline Phosphatase-Fused Mouse Prion Protein and Its Application in Toxic Aβ Oligomer Detection2022
- Author(s)
  Kaori Tsukakoshi, Rikako Kubo, Kazunori Ikebukuro
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 (23) Issue: 23 Pages: 14588-14588
- DOI
  10.3390/ijms232314588
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Effects of G-Quadruplex Ligands on the Topology, Stability, and Immunostimulatory Properties of G-Quadruplex-Based CpG Oligodeoxynucleotides2022
- Author(s)
  Anh Thi Tram Tu, Kazuaki Hoshi, Yue Ma, Taiji Oyama, Satoko Suzuki, Kaori Tsukakoshi, Kazuo Nagasawa, Kazunori Ikebukuro, Tomohiko Yamazaki
- Journal Title
  
  ACS Chem Biol
  
  Volume: 17 (7) Issue: 7 Pages: 1703-1713
- DOI
  10.1021/acschembio.1c00904
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-20H02876, KAKENHI-PROJECT-21K19057, KAKENHI-PLANNED-22H05038
[Journal Article] Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection2022
- Author(s)
  Saito Taro、Shimizu Yutaka、Tsukakoshi Kaori、Abe Koichi、Lee Jinhee、Ueno Kinuko、Asano Ryutaro、Jones Brian V.、Yamada Tomohiro、Nakano Tatsuki、Tong Jiaxing、Hishiki Asami、Hara Kodai、Hashimoto Hiroshi、Sode Koji、Toyo’oka Toshimasa、Todoroki Kenichiro、Ikebukuro Kazunori
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 203 Pages: 114027-114027
- DOI
  10.1016/j.bios.2022.114027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05757, KAKENHI-PROJECT-19H03360, KAKENHI-PROJECT-20H03197, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-22K06550
[Journal Article] Enhancement of DNAzymatic activity using iterative in silico maturation2022
- Author(s)
  Renzo A Fenati, Zifei Chen, Yasuko Yamagishi, Kaori Tsukakoshi, Kazunori Ikebukuor, Anjay Manian, Salvy P Russo, Tomohiko Yamazaki, Amanda V Ellis
- Journal Title
  
  J Mater Chem B
  
  Volume: 10 (43) Issue: 43 Pages: 8960-8969
- DOI
  10.1039/d2tb01638a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Data on G-quadruplex topology, and binding ability of G-quadruplex forming sequences found in the promoter region of biomarker proteins and those relations to the presence of nuclear localization signal in the proteins.2021
- Author(s)
  Lee J, Teramoto K, Yokoyama T, Ueno K, Tsukakoshi K, Sode K, Ikebukuro K.
- Journal Title
  
  Data Brief
  
  Volume: 36 Pages: 107028-107028
- DOI
  10.1016/j.dib.2021.107028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands2021
- Author(s)
  Hasegawa Hijiri、Sasaki Ikkei、Tsukakoshi Kaori、Ma Yue、Nagasawa Kazuo、Numata Shusuke、Inoue Yuuki、Kim Yeji、Ikebukuro Kazunori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 13159-13159
- DOI
  10.3390/ijms222313159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02876, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] G-quadruplex: Flexible conformational changes by cations, pH, crowding and its applications to biosensing.2021
- Author(s)
  Nishio M, Tsukakoshi K, Ikebukuro K
- Journal Title
  
  Biosens Bioelectron
  
  Volume: 178 Pages: 113030-113030
- DOI
  10.1016/j.bios.2021.113030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-19K22955
[Journal Article] Cytotoxic Abeta Protofilaments Are Generated in the Process of Abeta Fibril Disaggregation.2021
- Author(s)
  *Kaku, T., *Tsukakoshi, K. (*co-first author and corresponding author) & Ikebukuro, K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22(23) Issue: 23 Pages: 12780-12780
- DOI
  10.3390/ijms222312780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparal-lel Guanine-Quadruplex Structural Scaffold.2021
- Author(s)
  Safitri, F., Tu, A., Hoshi, K., Shobo, M., Zhao, D., Witarto, A., Sumarsono, S., Giri-Rachman, E., Tsukakoshi, K., Ikebukuro, K., and Yamazaki, T.
- Journal Title
  
  Sensors (Basel)
  
  Volume: 11(11) Issue: 11 Pages: 1617-1617
- DOI
  10.3390/biom11111617
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-18K04858, KAKENHI-PROJECT-21K19057
[Journal Article] G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol.2021
- Author(s)
  *Tsukakoshi, K., *Yamagishi, Y. (*co-first author), Kanazashi, M., Nakama, K., Oshikawa, D., Savory, N., Matsugami, A., Hayashi, F., Lee, J., Saito, T., Sode, K., Khunathai, K., Kuno, H. & Ikebukuro, K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 49 Issue: 11 Pages: 6069-6081
- DOI
  10.1093/nar/gkab388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] A Green Light-Regulated T7 RNA Polymerase Gene Expression System for Cyanobacteria.2020
- Author(s)
  Shono C, Ariyanti D, Abe K, Sakai Y, Sakamoto I, Tsukakoshi K, Sode K, Ikebukuro K.
- Journal Title
  
  Mar Biotechnol (NY)
  
  Volume: 23(1) Issue: 1 Pages: 31-38
- DOI
  10.1007/s10126-020-09997-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF2020
- Author(s)
  Lee J, Tatsumi A, Tsukakoshi K, Wilson ED, Abe K, Sode K, Ikebukuro K.
- Journal Title
  
  Sensors (Basel)
  
  Volume: 20(14) Issue: 14 Pages: 3878-3878
- DOI
  10.3390/s20143878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194
[Journal Article] Ethanol Detection at the Parts per Billion Level with Single‐Stranded‐DNA‐Modified Graphene Field‐Effect Transistors2019
- Author(s)
  Nozaki Ryo、Ikuta Takashi、Ueno Kinuko、Tsukakoshi Kaori、Ikebukuro Kazunori、Maehashi Kenzo
- Journal Title
  
  physica status solidi (b)
  
  Volume: 257 Issue: 2 Pages: 1900376-1900376
- DOI
  10.1002/pssb.201900376
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21963, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-18J21514, KAKENHI-PROJECT-19K22955
[Journal Article] G-Quadruplex Structure Improves the Immunostimulatory Effects of CpG Oligonucleotides2019
- Author(s)
  Hoshi, Kazuaki; Yamazaki, Tomohiko; Sugiyama, Yuuki; Tsukakoshi, Kaori; Tsugawa, Wakako; Sode, Koji; Ikebukuro, Kazunori
- Journal Title
  
  Nucleic acid therapeutics
  
  Volume: 29 (4) Issue: 4 Pages: 224-229
- DOI
  10.1089/nat.2018.0761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-18K04858
[Journal Article] Generation of C5-desoxy analogs of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability2019
- Author(s)
  Tanifuji, Ryo; Tsukakoshi, Kaori; Ikebukuro, Kazunori; Oikawa, Hideaki; Oguri, Hiroki
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 29 (14) Issue: 14 Pages: 1807-1811
- DOI
  10.1016/j.bmcl.2019.05.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PUBLICLY-19H04647, KAKENHI-PROJECT-17J00931, KAKENHI-PROJECT-18K19142, KAKENHI-PROJECT-16H06276
[Journal Article] Development of aptamers against unpurified proteins2017
- Author(s)
  S. Goto, K. Tsukakoshi, K. Ikebukuro
- Journal Title
  
  Biotechnol. Bioeng.
  
  Volume: 114(12) Issue: 12 Pages: 2706-2716
- DOI
  10.1002/bit.26389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14956
[Journal Article] Vital-Sign Characteristics of an Elderly Person during Walking2016
- Author(s)
  K. Tsukakoshi, K. Ikebukuro
- Journal Title
  
  Sensors and Materials
  
  Volume: 28(10) Pages: 1
- DOI
  10.18494/SAM.2016.1270
- ISSN
  0914-4935, 2435-0869
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14956
[Journal Article] Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers2016
- Author(s)
  Kaori Tsukakoshi, Yuri Ikuta, Koichi Abe, Wataru Yoshida, Keisuke Iida, Yue Ma, Kazuo Nagasawa, Koji Sode, Kazunori Ikebukuro
- Journal Title
  
  Chem. Commun.
  
  Volume: 52 Issue: 85 Pages: 12646-12649
- DOI
  10.1039/c6cc07552e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J08216, KAKENHI-PROJECT-26282214, KAKENHI-PROJECT-15K14956, KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-16K18908
[Journal Article] アミロイドβ代謝の分子機構から紐解くアルツハイマー病2014
- Author(s)
  塚越かおり、西道隆臣
- Journal Title
  
  生体の科学
  
  Volume: 65(1) Pages: 69-73
- Data Source
  KAKENHI-PROJECT-25889072
[Presentation] Docking simulationおよびMolecular dynamics simulationを用いたペプチドリガンドのin silico panning2024
- Author(s)
  Haruka Kawai, Daimei Miura, Sheng Tong, Ryutaro Asano, Wakako Tsugawa, Shoko Fujita, Ryuji Kawano, Takatsugu Hirokawa, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  日本化学会第104春季年会 (2024)
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] アプタマー酵素複合体と DNAzyme を用いた迅速かつ簡便な蛍光によるウイルス検出手法の開発2024
- Author(s)
  Yoshiki Shibazaki, Daimei Miura, Kaori Tsukakoshi, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  日本化学会第104春季年会 (2024)
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] アミロイド形成タンパク質に対するアプタマーの開発と分析への応用2024
- Author(s)
  塚越かおり、池袋一典
- Organizer
  電気化学会第91回大会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] メチル化DNAが鎖置換能を持つDNAポリメラーゼに与える影響2024
- Author(s)
  Mizuki Tomizawa, Kiwako Watanabe, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  日本化学会第104春季年会 (2024)
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] アプタマーと抗体を用いたproximity ligation assayによるモデルマウス脳内のアミロイドβオリゴマー検出2024
- Author(s)
  Toshiya Ibaraki, Jo Kamada, Chihiro Hosoi, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  日本化学会第104春季年会 (2024)
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Detection of CpG methylation based on structural change of G-quadruplex forming DNA oligonucleotide and its binding to heme proteins2023
- Author(s)
  Shintaro Inaba, Yudai Kitagawa, Kiwako Watanabe, Shusuke Numata, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  Biosensors 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Virus detection and on-site visualization of infected spot by sequential enzymatic reaction between antibody-enzyme complex and aptamer-DNAzyme2023
- Author(s)
  Erika Komiya, Shouhei Takamatsu, Daimei Miura, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  ISNAC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Development of ligands that specifically bind to oligomeric amyloid protein2023
- Author(s)
  Kaori Tsukakoshi
- Organizer
  Biological Chemistry on Membranes - Understanding and Engineering -
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] The methylated DNA changes the rate of strand displacement DNA polymerase amplification2023
- Author(s)
  Mizuki Tomizawa, Kiwako Watanabe, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  ISNAC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] アプタマー生物学を活用した脳内タンパク質の機能制御2023
- Author(s)
  塚越かおり
- Organizer
  日本化学会秋季事業第13回 CSJ化学フェスタ2023
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] 酵素活性を制御するDNAアプタマーの開発2023
- Author(s)
  塚越かおり、池袋一典
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] 核酸共有結合酵素の探索と特性評価および核酸-タンパク質連結モジュールとしての利用2023
- Author(s)
  Erika Komiya, Takeru Kanazu, Shouhei Takamatsu, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, Ryutaro Asano
- Organizer
  酵素工学研究会第90回講演会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] SARS CoV-2 ゲノムRNAにおけるグアニン四重鎖構造が、転写と翻訳に与える影響の評価系の構築2023
- Author(s)
  Norito Takeuchi, Kaori Tsukakoshi, Masayuki Tera, Shogo Sasaki, Rena Nohara, Kazunori Ikebukuro
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Exploration of DNA binding proteins for assembling covalently bound DNA-protein complexes and the application for biosensing system2023
- Author(s)
  Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  ISNAC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Exploration of DNA binding proteins for assembling covalently bound DNA-protein complexes and the application for biosensing system2023
- Author(s)
  Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  244th ECS Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Improvement of G-quadruplex-forming DNA aptamer for α-synuclein oligomer by loop modification2023
- Author(s)
  Akari Sato, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  ISNAC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] A Biosensor Platform for On-site Virus Visualization2023
- Author(s)
  Erika Komiya, Shouhei Takamatsu, Daimei Miura, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  244th ECS Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] アプタマー生物学を活用した脳内タンパク質の機能制御2023
- Author(s)
  塚越かおり
- Organizer
  日本化学会秋季事業第13回 CSJ化学フェスタ2023
- Data Source
  KAKENHI-ORGANIZER-22H05035
[Presentation] Detection of CpG methylation based on structural change of G-quadruplex forming DNA oligonucleotide and its binding to heme protein2022
- Author(s)
  Shintaro Inaba, Yudai Kitagawa, Kiwako Watanabe, Hijiri Hasegawa, Shusuke Numata, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Screening of aptamers specifically bind to various pollens2022
- Author(s)
  Hatsune Tanaka, Yusuke Kadoguchi, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Rapid and convenient viral detection based on sequential enzymatic reactions induced by antibody-enzyme complex and aptamer binding2022
- Author(s)
  Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Proximity ligation assay using amyloid oligomer-binding aptamer with antibody indicates Aβ1-42 and Aβ3pE-42 oligomer formation in brain2022
- Author(s)
  Kaori Tsukakoshi, Jo Kamada, Toshiya Ibaraki, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] ループ改変によるαシヌクレインオリゴマー結合アプタマーの改良2022
- Author(s)
  佐藤星, 塚越かおり, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] タンパク質機能を制御するDNAアプタマーの開発：「アプタマー生物学」の創成へ2022
- Author(s)
  塚越かおり, 小林俊一, 守屋里紗, 仲和奏, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Proximity ligation assay using amyloid oligomer-binding aptamer with antibody indicates Aβ1-42 and Aβ3pE-42 oligomer formation in brain2022
- Author(s)
  Kaori Tsukakoshi, Jo Kamada, Toshiya Ibaraki, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] アプタマー・抗体を用いたProximity ligation assayによる脳内Aβオリゴマーの検出2022
- Author(s)
  塚越かおり, 茨木利哉, 鎌田晟, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Exploration and application of DNA binding proteins as versatile tool for fabrication of biosensing elements2022
- Author(s)
  Erika Komiya, Shouhei Takamatsu, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Detection of CpG methylation based on structural change of G-quadruplex forming DNA oligonucleotide and its binding to heme protein2022
- Author(s)
  Shintaro Inaba, Yudai Kitagawa, Kiwako Watanabe, Hijiri Hasegawa, Shusuke Numata, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Anti-idiotype aptamer against Bevacizumab and its affinity change depending on pH2022
- Author(s)
  Kazunori Ikebukuro, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Ryutaro Asano, Tomohiro Yamada, Tatsuki Nakano, Kodai Hara, Hitoshi Hashimoto, Kenichiro Todoroki
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Screening of aptamers specifically bind to various pollens2022
- Author(s)
  Hatsune Tanaka, Yusuke Kadoguchi, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Anti-idiotype aptamer against Bevacizumab and its affinity change depending on pH2022
- Author(s)
  Kazunori Ikebukuro, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Ryutaro Asano, Tomohiro Yamada, Tatsuki Nakano, Kodai Hara, Hitoshi Hashimoto, Kenichiro Todoroki
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Screening of aptamers specifically bind to various pollens2022
- Author(s)
  Hatsune Tanaka, Yusuke Kadoguchi, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Exploration and application of DNA binding proteins as versatile tool for fabrication of biosensing elements2022
- Author(s)
  Erika Komiya, Shouhei Takamatsu, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Detection of CpG methylation based on structural change of G-quadruplex forming DNA oligonucleotide and its binding to heme protein2022
- Author(s)
  Shintaro Inaba, Yudai Kitagawa, Kiwako Watanabe, Hijiri Hasegawa, Shusuke Numata, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] ループ改変によるαシヌクレインオリゴマー結合アプタマーの改良2022
- Author(s)
  佐藤星, 塚越かおり, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Exploration and application of DNA binding proteins as versatile tool for fabrication of biosensing elements2022
- Author(s)
  Erika Komiya, Shouhei Takamatsu, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Rapid and convenient viral detection based on sequential enzymatic reactions induced by antibody-enzyme complex and aptamer binding2022
- Author(s)
  Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] タンパク質機能を制御するDNAアプタマーの開発：「アプタマー生物学」の創成へ2022
- Author(s)
  塚越かおり, 小林俊一, 守屋里紗, 仲和奏, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-ORGANIZER-22H05035
[Presentation] ループ改変によるαシヌクレインオリゴマー結合アプタマーの改良2022
- Author(s)
  佐藤星, 塚越かおり, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] アプタマー・抗体を用いたProximity ligation assayによる脳内Aβオリゴマーの検出2022
- Author(s)
  塚越かおり, 茨木利哉, 鎌田晟, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] アプタマー・抗体を用いたProximity ligation assayによる脳内Aβオリゴマーの検出2022
- Author(s)
  塚越かおり, 茨木利哉, 鎌田晟, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] タンパク質機能を制御するDNAアプタマーの開発：「アプタマー生物学」の創成へ2022
- Author(s)
  塚越かおり, 小林俊一, 守屋里紗, 仲和奏, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Proximity ligation assay using amyloid oligomer-binding aptamer with antibody indicates Aβ1-42 and Aβ3pE-42 oligomer formation in brain2022
- Author(s)
  Kaori Tsukakoshi, Jo Kamada, Toshiya Ibaraki, Kazunori Ikebukuro
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Anti-idiotype aptamer against Bevacizumab and its affinity change depending on pH2022
- Author(s)
  Kazunori Ikebukuro, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Ryutaro Asano, Tomohiro Yamada, Tatsuki Nakano, Kodai Hara, Hitoshi Hashimoto, Kenichiro Todoroki
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] タンパク質機能を制御するDNAアプタマーの開発：「アプタマー生物学」の創成へ2022
- Author(s)
  塚越かおり, 小林俊一, 守屋里紗, 仲和奏, 池袋一典
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Rapid and convenient viral detection based on sequential enzymatic reactions induced by antibody-enzyme complex and aptamer binding2022
- Author(s)
  Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, and Ryutaro Asano
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05038
[Presentation] Evaluation of the aptamer binding to the target molecule in the mist using quartz crystal units for detection of virus in the air2021
- Author(s)
  Ayaka Sone, Hatsune Tanaka, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  2021年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Evaluation of the structural effects of CpG methylation on the dopamine receptor gene(DRD2)2021
- Author(s)
  Shinataro INABA, Yudai Kitagawa, Shiori Saito, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Shunsuke Numata, Hijiri Hasegawa, Kazunori Ikebukuro
- Organizer
  2021年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Evaluation of the structural effects of CpG methylation on the dopamine receptor gene(DRD2)2021
- Author(s)
  Shinataro INABA, Yudai Kitagawa, Shiori Saito, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Shunsuke Numata, Hijiri Hasegawa, Kazunori Ikebukuro
- Organizer
  2021年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Development of functional oligonucleotides forming G-quadruplex structure by using topological structure evaluation based on CD spectrum analysis combined with principal component analysis2021
- Author(s)
  Kaori Tsukakoshi, Satoko Suzuki, Taiji Oyama, Akari Sato, Anh Thi Tram Tu, Yasuo Horiguchi, Koushi Nagamori, Tomohiko Yamazaki, Kazunori Ikebukuro
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Aptameric enzyme subunit enhances the peroxidase activity of myoglobin against luminol2021
- Author(s)
  Kaori Tsukakoshi,Yasuko Yamagishi, Mana Kanazashi, Kenta Nakama, Daiki Oshikawa, Nasa Savory, Akimasa Matsugami, Fumiaki Hayashi, Jinhee Lee, Taiki Saito, Koji Sode, Kanjana Khunathai, Hitoshi Kuno, Kazunori Ikebukuro
- Organizer
  ISNAC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Development of functional oligonucleotides forming G-quadruplex structure by using topological structure evaluation based on CD spectrum analysis combined with principal component analysis2021
- Author(s)
  Kaori Tsukakoshi, Satoko Suzuki, Taiji Oyama, Akari Sato, Anh Thi Tram Tu, Yasuo Horiguchi, Koushi Nagamori, Tomohiko Yamazaki, Kazunori Ikebukuro
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Aptameric enzyme subunit enhances the peroxidase activity of myoglobin against luminol2021
- Author(s)
  Kaori Tsukakoshi,Yasuko Yamagishi, Mana Kanazashi, Kenta Nakama, Daiki Oshikawa, Nasa Savory, Akimasa Matsugami, Fumiaki Hayashi, Jinhee Lee, Taiki Saito, Koji Sode, Kanjana Khunathai, Hitoshi Kuno, Kazunori Ikebukuro
- Organizer
  ISNAC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Analysis of inosine introduced aptamer against SARS-CoV-2 S1 protein RBD2021
- Author(s)
  Wakana HAYASHI, Kaori TSUKAKOSHI, Kazunori IKEBUKURO
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] グアニン四重鎖構造を用いたDNAアジュバントの開発2021
- Author(s)
  山崎智彦, TU Thi Tram Anh, 星和明、Fika Ayu Safitri, 塚越かおり、池袋一典
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Specific detection of a therapeutic antibody using an anti-idiotype DNA aptamer and drastic improvement of its affinity by pH optimization2021
- Author(s)
  Yutaka Shimizu, Lisa Moriya, Taro Saito, Kaori Tsukakoshi, Koichi Abe, Jinhee Lee, Kinuko Ueno, Ryutaro Asano, Brian V. Jones, Tomohiro Yamada, Tatsuki Nakano, Jiaxing Tong, Asami Hishiki, Kodai Hara, Hiroshi Hashimoto, Koji Sode, Toshimasa Toyo’oka, Kenichiro Todoroki, and Kazunori Ikebukuro
- Organizer
  BIOSENSORS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Evaluation of the aptamer binding to the target molecule in the mist using quartz crystal units for detection of virus in the air2021
- Author(s)
  Ayaka Sone, Hatsune Tanaka, Kaori Tsukakoshi, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro
- Organizer
  2021年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Analysis of inosine introduced aptamer against SARS-CoV-2 S1 protein RBD2021
- Author(s)
  Wakana HAYASHI, Kaori TSUKAKOSHI, Kazunori IKEBUKURO
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] グアニン四重鎖構造を用いたDNAアジュバントの開発2021
- Author(s)
  山崎智彦, TU Thi Tram Anh, 星和明、Fika Ayu Safitri, 塚越かおり、池袋一典
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Specific detection of a therapeutic antibody using an anti-idiotype DNA aptamer and drastic improvement of its affinity by pH optimization2021
- Author(s)
  Yutaka Shimizu, Lisa Moriya, Taro Saito, Kaori Tsukakoshi, Koichi Abe, Jinhee Lee, Kinuko Ueno, Ryutaro Asano, Brian V. Jones, Tomohiro Yamada, Tatsuki Nakano, Jiaxing Tong, Asami Hishiki, Kodai Hara, Hiroshi Hashimoto, Koji Sode, Toshimasa Toyo’oka, Kenichiro Todoroki, and Kazunori Ikebukuro
- Organizer
  BIOSENSORS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] 病態生理学的知見に基づいた毒性アミロイドβオリゴマー識別リガンドの開発2020
- Author(s)
  塚越かおり、久保梨夏子、池袋一典
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] チャネル電流計測法を用いた脂質膜上におけるAβのポア構造形成過程の解析2020
- Author(s)
  塚越かおり、沼口友理、清水啓佑、川野竜司、池袋一典
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Evaluation of structural features of α-S1-casein detected from amyloid deposits in canine mammary tumor2020
- Author(s)
  Toshisuke Kaku, Rikako Kubo, Kaori Tsukakoshi, Tomoaki Murakami, Kazunori Ikebukuro
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Improvement of fluorescent aptamer focusing on its G-quadurplex and design of pH-sensitive Baby Spinach aptamer2020
- Author(s)
  Kinuko UENO, Kaori TSUKAKOSHI, Alessandro PORCHETTA, Francesco RICCI, Kazunori IKEBUKURO
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Evaluation of structural features of α-S1-casein detected from amyloid deposits in canine mammary tumor2020
- Author(s)
  Toshisuke Kaku, Rikako Kubo, Kaori Tsukakoshi, Tomoaki Murakami, Kazunori Ikebukuro
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Improvement of fluorescent aptamer focusing on its G-quadurplex and design of pH-sensitive Baby Spinach aptamer2020
- Author(s)
  Kinuko UENO, Kaori TSUKAKOSHI, Alessandro PORCHETTA, Francesco RICCI, Kazunori IKEBUKURO
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] チャネル電流計測法を用いた脂質膜上におけるAβのポア構造形成過程の解析2020
- Author(s)
  塚越かおり、沼口友理、清水啓佑、川野竜司、池袋一典
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] 病態生理学的知見に基づいた毒性アミロイドβオリゴマー識別リガンドの開発2020
- Author(s)
  塚越かおり、久保梨夏子、池袋一典
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Ligand-based functional improvement of G-quadruplex- forming DNA aptamers2019
- Author(s)
  Kaori Tsukakoshi, Yuri Ikuta, Kaoru Konda, Ikkei Sasaki, Kazuo Nagasawa, Yoshio Kato, Chikashi Nakamura, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Effects of cation and G-quadruplex(G4) ligands on topology and binding ability of Cas9-binding aptamer.2019
- Author(s)
  Sasaki I, Maui Nishio, Tsukakoshi K, Ma Y, Nagasawa K, Yamagishi Y, Kato K, Nakamura K, Kazunori Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Improvement and design of pH-sensitive Baby Spinach aptamer by fusing triplex forming sequence.2019
- Author(s)
  Ueno K, Tsukakoshi K, Porchetta A, Ricci F, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Evaluation of the effect of CpG methylation on i-motif structure located in the CpG islands.2019
- Author(s)
  Oshikawa D, Tsukakoshi K, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Aβ線維の脱凝集によるAβオリゴマー形成の検討2019
- Author(s)
  郭俊佑, 塚越かおり, 池袋一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Aβオリゴマーの検出に向けたアルカリホスファターゼ融合プリオンタンパク質の開発2019
- Author(s)
  久保　梨夏子、塚越　かおり、李　鎭煕、早出　広司、池袋　一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] 蛍光発光アプタマーに対する三重鎖形成配列の付加による蛍光強度の増強2019
- Author(s)
  上野　絹子、塚越　かおり、Porchetta Alessandro、Ricci Francesco、池袋　一典
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Topological structure evaluation of G-quadruplexes using high-throughput CD system2019
- Author(s)
  Satoko Suzuki, Kaori Tsukakoshi, Taiji Oyama, Yasuo Horiguchi, Koushi Nagamori, and Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Ligand-based functional improvement of G-quadruplex- forming DNA aptamers.2019
- Author(s)
  Tsukakoshi K, Ikuta Y, Konda K, Sasaki I, Nagasawa K, Kato Y, Nakamura C, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] アプタマーを用いたAβオリゴマーの組織染色法の検討2019
- Author(s)
  塚越かおり, 鎌田晟, 細井千尋, 池袋一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Improvement in binding property of the anti-idiotype aptamer against bevacizumab based on structural information.2019
- Author(s)
  Shimizu Y, Tsukakoshi K, Asano R, Nakano T, Tong J, Hishiki A, Hara K, Hashimoto H, Toyo’oka T, Kenichiro Todoroki K, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Topological structure evaluation of G-quadruplexes using high-throughput CD system.2019
- Author(s)
  Suzuki S, Tsukakoshi K, Oyama T, Horiguchi Y, Nagamori K, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Aβ線維の脱凝集によるAβオリゴマー形成の検討2019
- Author(s)
  郭　俊佑、塚越　かおり、池袋一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Enhancement of peroxidase activity of myoglobin by parallel G-quadruplex forming aptamer2019
- Author(s)
  Kaori Tsukakoshi, Mana Kanazashi, Kenta Nakama, Akimasa Matsugami, Fumiaki Hayashi, Kanjana Khunathai, Hitoshi Kuno, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] DNAアプタマーを用いたBevacizumabの検出法の開発2019
- Author(s)
  清水裕, 齊藤太郎, 塚越かおり, 山田朋宏, 轟木堅一郎, 池袋一典
- Organizer
  2019年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] 円二色性スペクトル解析に基づくαシヌクレインオリゴマー結合アプタマーの構造活性評価2019
- Author(s)
  塚越　かおり, 鎌田　晟, 鈴木　仁子, 堀口　靖夫, 永森　浩司, 池袋　一典
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] DNAアプタマーを用いたBevacizumabの検出法の開発2019
- Author(s)
  清水　裕、齊藤　太郎、塚越　かおり、山田　朋宏、轟木　堅一郎、池袋　一典
- Organizer
  2019年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] プロモーター領域に存在する i-motif の安定性に CpG のメチル化が与える効果2019
- Author(s)
  押川　大起、塚越　かおり、池袋　一典
- Organizer
  第13回バイオ関連シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Evaluation of the effect of CpG methylation on i-motif structure located in the CpG islands2019
- Author(s)
  Daiki Oshikawa, Kaori Tsukakoshi, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] 蛍光発光アプタマーに対する三重鎖形成配列の付加による蛍光強度の増強2019
- Author(s)
  上野絹子, 塚越かおり, Porchetta Alessandro, Ricci Francesco, 池袋一典
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] プロモーター領域に存在する i-motif の安定性に CpG のメチル化が与える効果2019
- Author(s)
  押川　大起, 塚越　かおり, 池袋　一典
- Organizer
  第13回バイオ関連シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Improvement and design of pH-sensitive Baby Spinach aptamer by fusing triplex forming sequence2019
- Author(s)
  Kinuko Ueno, Kaori Tsukakoshi, Alessandro Porchetta, Francesco Ricci, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] イヌの乳腺腫瘍随伴アミロイドーシスにおける前駆タンパク同定の試み(続報)2019
- Author(s)
  村上　智亮、郭　俊佑、久保　梨夏子、塚越　かおり、佐々　悠木子、亀谷　富由樹
- Organizer
  第七回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] ミオグロビン結合アプタマーによる、ミオグロビンのペルオキシダーゼ活性の増強2019
- Author(s)
  中間　健太、山岸　恭子、金指　真菜、久野　斉、塚越　かおり、池袋　一典
- Organizer
  2019年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Enhancement of peroxidase activity of myoglobin by parallel G-quadruplex forming aptamer.2019
- Author(s)
  Tsukakoshi K, Kanazashi M, Nakama K, Matsugami A, Hayashi F, Khunathai K, Kuno H, Ikebukuro K
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] 円二色性スペクトル解析に基づくαシヌクレインオリゴマー結合アプタマーの構造活性評価2019
- Author(s)
  塚越　かおり、鎌田　晟、鈴木　仁子、堀口　靖夫、永森　浩司、池袋　一典
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] Effects of cation and G-quadruplex(G4) ligands on topology and binding ability of Cas9-binding aptamer2019
- Author(s)
  Ikkei Sasaki, Maui Nishio, Kaori Tsukakoshi, Yue Ma, Kazuo Nagasawa, Ayana Yamagishi, Yoshio Kato, Chikashi Nakamura, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Improvement in binding property of the anti-idiotype aptamer against bevacizumab based on structural information2019
- Author(s)
  Yutaka Shimizu, Kaori Tsukakoshi, Ryutaro Asano, Tatsuki Nakano, Jiaxing Tong, Asami Hishiki, Kodai Hara, Hiroshi Hashimoto, Toshimasa Toyo’oka, Kenichiro Todoroki, Kazunori Ikebukuro
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Aβオリゴマーの検出に向けたアルカリホスファターゼ融合プリオンタンパク質の開発2019
- Author(s)
  久保梨夏子, 塚越かおり, 李鎭煕, 早出広司, 池袋一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] アプタマーを用いたAβオリゴマーの組織染色法の検討2019
- Author(s)
  塚越　かおり、鎌田　晟、細井　千尋、池袋　一典
- Organizer
  第３８回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0194
[Presentation] ミオグロビン結合アプタマーによる, ミオグロビンのペルオキシダーゼ活性の増強2019
- Author(s)
  中間健太, 山岸恭子, 金指真菜, 久野斉, 塚越かおり, 池袋一典
- Organizer
  2019年電気化学秋季大会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] イヌの乳腺腫瘍随伴アミロイドーシスにおける前駆タンパク同定の試み(続報)2019
- Author(s)
  村上智亮, 郭俊佑, 久保梨夏子, 塚越かおり, 佐々悠木子, 亀谷富由樹
- Organizer
  第七回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15694
[Presentation] Proximity Ligation Assayによるアミロイドβ特異的検出2017
- Author(s)
  塚越かおり、細井千尋、池袋一典
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] Aβオリゴマーの高感度検出に向けたProximity Ligation Assayの開発2017
- Author(s)
  塚越かおり、細井千尋、池袋一典
- Organizer
  第３６回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] BINDING PROPERTIES OF AMYLOID OLIGOMER-BINDING DNA APTAMERS AGAINST AMYLOID BETA OLIGOMERS2017
- Author(s)
  K. Tsukakoshi, C. Hosoi, K. Sode, K. Ikebukuro
- Organizer
  13th International Conference on Alzheimer’s and Parkinson’s Diseases
- Place of Presentation
  ウィーン（オーストリア）
- Year and Date
  2017-03-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] アミロイドオリゴマー結合アプタマーを用いた、核酸増幅に基づく水溶性アミロイドβオリゴマーの検出2017
- Author(s)
  塚越かおり、細井千尋、池袋一典
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学日吉キャンパス（横浜）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] グアニン四重鎖特異的リガンドを用いたDNAアプタマーの構造制御2016
- Author(s)
  塚越かおり、生田結里、飯田圭介、馬悦、長澤和夫、早出広司、池袋一典
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂、もてなしドーム地下イベント広場（金沢）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] Development of multivalent aptamers for high-sensitive detection of target proteins2016
- Author(s)
  K. Tsukakoshi, C. Takahashi, Y. Ikuta, K. Iida, K. Nagasawa, K. Sode, K. Ikebukuro
- Organizer
  Biosensors 2016
- Place of Presentation
  ヨーテボリ（スウェーデン）
- Year and Date
  2016-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] APPノックインマウスにおけるリン酸化タウ病態の解析2015
- Author(s)
  塚越かおり, 藤岡亮, 細木恵美, 高野二郎, 斉藤貴志, 高島明彦, 西道隆臣
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール青森・ホテル青森（青森県青森市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K14956
[Presentation] POST-TRANSLATIONAL MODIFICATION(S) OF TAU PROTEIN IN APP KNOCK-IN MICE
- Author(s)
  K. Tsukakoshi, J. Takano, R. Fujioka, E. Hosoki, T. Saito, A. Takashima and T.C. Saido
- Organizer
  ADPD2015
- Place of Presentation
  Acropolis 1, Nice, France
- Year and Date
  2015-03-18 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-25889072
[Presentation] APP・タウダブルノックインマウスの作製
- Author(s)
  塚越かおり、斉藤貴志、西道隆臣
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-25889072

1. Inada Masaki (80401454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 富成司 (50734878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 平田美智子 (40544060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 浅野竜太郎 (80323103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 堀由起子 (80610683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 橋本翔子 (50632890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山岸彩奈 (00778293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松村洋寿 (60741824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAYASHI Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 生田昂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 藤田恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 池袋一典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 轟木堅一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 村上智亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 原幸大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 長澤和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 鈴木勇輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsukakoshi Kaori 塚越 かおり

TSUKAKOSHI Kaori 塚越 かおり

Research Projects

Research Products

Co-Researchers

Creation of aptameric biologyArea Organizer

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アプタマー生物学の創成による脳内恒常性維持機構の解明Principal Investigator

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活性増強アプタマーを用いた脳内恒常性維持機構制御マウスの開発Principal Investigator

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Analysis of neurodegenerative mechanisms based on the development of beta amyloid oligomer-selective proteasesPrincipal Investigator

Principal Investigator

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Investigation of collagenolytic metabolisms in bone metastatic cancer migration and invasion for the novel drug development

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Investigation of amyloid beta oligomerization process via aggregation and disaggregationPrincipal Investigator

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Identification of surrogate plasma markers for early diagnosis of Alzheimer's diseasePrincipal Investigator

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[Journal Article] Aptamer-enhanced particle aggregation inhibition assay for simple homogeneous protein detection using DNA aptamer and thermo-responsive magnetic nanoparticles.2024

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[Journal Article] Exploration and Application of DNA-Binding Proteins to Make a Versatile DNA-Protein Covalent-Linking Patch (D-Pclip): The Case of a Biosensing Element2024

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[Journal Article] Development of a liquid chromatography-based versatile bioanalysis for bevacizumab based on pretreatment combining aptamer affinity purification and centrifugal ultrafiltration concentration2023

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[Journal Article] Identification of novel amyloidosis in dogs: α-S1-casein acquires amyloidogenicity in mammary tumor by overexpression and N-terminal truncation2023

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[Journal Article] Real-time monitoring of the amyloid β1-42 monomer-to-oligomer channel transition using a lipid bilayer system2023

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[Journal Article] The state of water molecules induces changes in the topologies and interactions of G-quadruplex DNA aptamers in hydrated ionic liquid2022

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[Journal Article] CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands2022

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Tsukakoshi Kaori 塚越かおり

TSUKAKOSHI Kaori 塚越かおり