Ito Takeshi 伊東剛

Researcher Number	20733075
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Complex systems / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator 細胞接着 / 転移 / 数理モデル / 肺腺がん / 細胞接着分子 / CADM1 / マウスモデル / 小細胞肺がん / がん転移 / 細胞間相互作用 … More / タンパク質ライブラリー / 浸潤 / ゲフィチニブ / 薬剤耐性 / EGFR-TKI / 腫瘍生物学 / Hippo経路 … More Except Principal Investigator 分子間結合 / がん浸潤・転移 / 免疫チェックポイント / 免疫グロブリンスーパーファミリータンパク質 / KRAS / 肺癌 / 胃腸上皮分化 / HNF4A / Non-TRU / 大細胞神経内分泌癌 / 小細胞癌 / 神経内分泌分化 / 胃腸上皮型 / neuroendocrine tumor / HGNEC / lung adenocarcinoma / non-TRU type / SMARCA4 / LCNEC / SCLC / 肺腺癌 / TTF-1 / HNF4α / 免疫グロブリンスーパーファミリー / 浸潤、転移 / 免疫グロブリンスーパーファミリ― / 消化器がん / 神経内分泌腫瘍 / 小細胞肺がん / 薬剤耐性 / 肺がん / 腫瘍免疫 / 糖鎖 / がんの浸潤、転移 Less

VSIG4を標的とした免疫チェックポイント阻害療法の確立Principal Investigator
- Principal Investigator
  
  伊東剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Elucidation of carcinogenesis, metastasis and metabolic mechanisms in HNF4A-positive lung tumor
- Principal Investigator
  
  Matsubara Daisuke
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba
Analysis of the molecular mechanism underlying CADM1-induced growth and metastasis of small-cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Ito Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Development of novel intervening approaches to cancer progression by comprehensive analyses of interactions between cell adhesion molecules
- Principal Investigator
  
  Murakami Yoshinori
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
Mathematical analysis of cancer metastasis focused on cancer cell-endothelial cell interactionsPrincipal Investigator
- Principal Investigator
  
  伊東剛
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Development of novel diagnostic and therapeutic approaches to cancer by analyzing specific features of the immunoglobulin superfamily of molecules.
- Principal Investigator
  
  MURAKAMI Yoshinori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Identification of trans-interacting receptors for CADM1Principal Investigator
- Principal Investigator
  
  Ito Takeshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
肺腺がんのゲフィチニブ耐性機構における細胞接着分子CADM1の役割の数理的解明Principal Investigator
- Principal Investigator
  
  伊東剛
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Involvement of CADM1 in the regulation of Hippo pathwayPrincipal Investigator
- Principal Investigator
  
  Ito Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC.2024
- Author(s)
  Aya Shiba-Ishii; Takayuki Isagawa; Toshihiro Shiozawa; Naoko Mato; Tomoki Nakagawa; Yurika Takada; Kanon Hirai; Jeongmin Hong; Anri Saitoh; Norihiko Takeda; Toshiro Niki; Yoshinori Murakami; Daisuke Matsubara
- Journal Title
  
  BBA - Molecular Basis of Disease
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102
[Journal Article] <scp>IGSF3</scp> is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium2024
- Author(s)
  Guo Yue、Kasai Yutaka、Tanaka Yuto、Ohashi‐Kumagai Yuki、Sakamoto Takeharu、Ito Takeshi、Murakami Yoshinori
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 1936-1947
- DOI
  10.1111/cas.16166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14558, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-24K02319
[Journal Article] Histologic transformation of non‐small‐cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms2024
- Author(s)
  Shiba‐Ishii Aya、Takemura Noriko、Kawai Hitomi、Matsubara Daisuke
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 7 Pages: 2138-2146
- DOI
  10.1111/cas.16192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102, KAKENHI-PROJECT-23K14469
[Journal Article] Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC2024
- Author(s)
  Shiba-Ishii Aya、Isagawa Takayuki、Shiozawa Toshihiro、Mato Naoko、Nakagawa Tomoki、Takada Yurika、Hirai Kanon、Hong Jeongmin、Saitoh Anri、Takeda Norihiko、Niki Toshiro、Murakami Yoshinori、Matsubara Daisuke
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1870 Issue: 6 Pages: 167249-167249
- DOI
  10.1016/j.bbadis.2024.167249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102, KAKENHI-PROJECT-24K02319, KAKENHI-PROJECT-22K06945
[Journal Article] Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features2024
- Author(s)
  Kawai Hitomi、Miura Tamaki、Kawamatsu Natsumi、Nakagawa Tomoki、Shiba-Ishii Aya、Yoshimoto Taichiro、Amano Yusuke、Kihara Atsushi、Sakuma Yuji、Fujita Kazutaka、Shibano Tomoki、Ishikawa Shumpei、Ushiku Tetsuo、Fukayama Masashi、Tsubochi Hiroyoshi、Endo Shunsuke、Hagiwara Koichi、Matsubara Daisuke、Niki Toshiro
- Journal Title
  
  Virchows Archiv
  
  Volume: 486 Issue: 2 Pages: 343-354
- DOI
  10.1007/s00428-024-03816-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-23K14469, KAKENHI-PROJECT-22K06945, KAKENHI-PROJECT-22K15412
[Journal Article] Histologic transformation of non-small-cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms2024
- Author(s)
  Aya Shiba-Ishii, Noriko Takemura, Hitomi Kawai, Daisuke Matsubara
- Journal Title
  
  Cancer Science
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102
[Journal Article] IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium.2024
- Author(s)
  Yue G, Kasai Y, Yuto T, Ohashi-Kumagai Y, Sakamoto T, Ito T, Murakami Y.
- Journal Title
  
  Cancer Science
  
  Volume: in press Pages: 16166-16166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03525
[Journal Article] Genomic landscape and its prognostic significance in stage III colorectal cancer: JCOG1506A1, an ancillary of JCOG0910.2023
- Author(s)
  Shida D, Kuchiba A, Shibata T, Hamaguchi T, Yamasaki S, Ito M, Kobatake T, Tonooka T, Masaki T, Shiozawa M, Takii Y, Uetake H, Okamura S, Ojima H, Kazama S, Takeyama H, Kanato K, Shimada Y, Murakami Y, Kanemitsu Y.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 8 Pages: 3352-3363
- DOI
  10.1111/cas.15834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03525
[Journal Article] Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction2023
- Author(s)
  Miyazawa Kazuo、Ito Kaoru、Ito Masamichi、Zou Zhaonan、Kubota Masayuki、Nomura Seitaro、Matsunaga Hiroshi、Koyama Satoshi、Ieki Hirotaka、et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 2 Pages: 187-197
- DOI
  10.1038/s41588-022-01284-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16128, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02919, KAKENHI-PROJECT-20J01343, KAKENHI-PROJECT-22KJ1890, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ3142, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-23K24602
[Journal Article] Helicobacter pylori, homologous-recombination genes, and gastric cancer2023
- Author(s)
  Usui Yoshiaki, Taniyama Yukari, Hatakeyama Masanori, Matsuo Keitaro, Momozawa Yukihide, etal.
- Journal Title
  
  The New England Journal of Medicine
  
  Volume: 388 Issue: 13 Pages: 1181-1190
- DOI
  10.1056/nejmoa2211807
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04804, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-20K10463, KAKENHI-PROJECT-23K24468, KAKENHI-PROJECT-22H04923
[Journal Article] Determining Whether YAP1 and POU2F3 Are Antineuroendocrine Factors2022
- Author(s)
  Matsuoka Ryota、Kawai Hitomi、Ito Takeshi、Matsubara Daisuke
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 17 Issue: 9 Pages: 1070-1073
- DOI
  10.1016/j.jtho.2022.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-22K15418, KAKENHI-PROJECT-23K24102
[Journal Article] Usefulness of circulating tumor DNA by targeting human papilloma virus-derived sequences as a biomarker in p16-positive oropharyngeal cancer.2022
- Author(s)
  Akashi K, Sakai T, Fukuoka O, Saito Y, Yoshida M, Ando M, Ito T, Murakami Y, Yamasoba T.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 572-572
- DOI
  10.1038/s41598-021-04307-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21539, KAKENHI-PROJECT-18K16833, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-21K09556, KAKENHI-PROJECT-21K09578, KAKENHI-PROJECT-22K09726
[Journal Article] Hemiarthroplasty for tumor-induced osteomalacia caused by tumor localized in femoral head: a case report2022
- Author(s)
  Arita Sayaka、Nishino Tomofumi、Mitani Yuuki、Sakashita Kotaro、Totsuka Sho、Watanabe Ryunosuke、Mishima Hajime、Kawai Hitomi、Matsubara Daisuke、Oda Yoshionao、Yamazaki Masashi
- Journal Title
  
  Journal of Surgical Case Reports
  
  Volume: 2022 Issue: 10 Pages: 1-3
- DOI
  10.1093/jscr/rjac478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24102
[Journal Article] Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?2022
- Author(s)
  Kawai Hitomi、Matsuoka Ryouta、Ito Takeshi、Matsubara Daisuke
- Journal Title
  
  Frontiers in Bioscience-Landmark
  
  Volume: 27 Issue: 3 Pages: 108-108
- DOI
  10.31083/j.fbl2703108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-22K15418, KAKENHI-PROJECT-21K15381
[Journal Article] Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.2022
- Author(s)
  Kasai Y, Gan SP, Funaki T, Ohashi-Kumagai Y, Tominaga M, Shiu S-J, Suzuki D, Matsubara D, Sakamoto T, Sakurai-Yageta M, Ito T, Murakami Y.
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 5 Pages: 1-2
- DOI
  10.1111/cas.15307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21539, KAKENHI-PUBLICLY-20H05028, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-23K24102
[Journal Article] NFAT indicates nucleocytoplasmic damped oscillation via its feedback modulator2021
- Author(s)
  Muramatsu Masashi、Ito Takeshi、Shimoji Hokuto、Komiya Miko、Miyamura Yuri、Nishiyama Koichi、Suzuki Takashi、Minami Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 571 Pages: 201-209
- DOI
  10.1016/j.bbrc.2021.07.072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0026, KAKENHI-PLANNED-16H06576, KAKENHI-PUBLICLY-19H04972, KAKENHI-PUBLICLY-20H05028, KAKENHI-PROJECT-19H04446, KAKENHI-PROJECT-21H02917, KAKENHI-PROJECT-21K07091, KAKENHI-INTERNATIONAL-16K21739
[Journal Article] CADM1 promotes malignant features of small-cell lung cancer by recruiting 4.1R to the plasma membrane2021
- Author(s)
  Funaki Toko、Ito Takeshi、Tanei Zen-ichi、Goto Akiteru、Niki Toshiro、Matsubara Daisuke、Murakami Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 172-178
- DOI
  10.1016/j.bbrc.2020.11.121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K07454, KAKENHI-PROJECT-18H02634, KAKENHI-PROJECT-20J12314, KAKENHI-PROJECT-19K16708, KAKENHI-PROJECT-20K21539, KAKENHI-PROJECT-20H03525
[Journal Article] Short somatic alterations at the site of copy number variation in breast cancer2020
- Author(s)
  Murakami Fumi、Tsuboi Yumi、Takahashi Yuka、Horimoto Yoshiya、Mogushi Kaoru、Ito Takeshi、Emi Mitsuru、Matsubara Daisuke、Shibata Tatsuhiro、Saito Mitsue、Murakami Yoshinori
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 1 Pages: 444-453
- DOI
  10.1111/cas.14630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-20K21539, KAKENHI-PROJECT-20H03525
[Journal Article] CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis2020
- Author(s)
  Tsuboi Yumi、Oyama Masaaki、Kozuka-Hata Hiroko、Ito Akihiko、Matsubara Daisuke、Murakami Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 3 Pages: 854-860
- DOI
  10.1016/j.bbrc.2020.05.103
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-20K21539, KAKENHI-PLANNED-16H06578, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-18K07049
[Journal Article] CADM1 associates with Hippo pathway core kinases; membranous coexpression of CADM1 & LATS2 in lung tumors predicts good prognosis.2019
- Author(s)
  Takeshi Ito Atsuko Nakamura Ichidai Tanaka Yumi Tsuboi Teppei Morikawa Jun Nakajima Daiya Takai Masashi Fukayama Yoshitaka Sekido Toshiro Niki Daisuke Matsubara（Corresponding author） Yoshinori Murakami
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 7 Pages: 2284-2295
- DOI
  10.1111/cas.14040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K16708
[Journal Article] Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification2019
- Author(s)
  Ito Takeshi, Kumagai Yuki, Itano Keiko, Maruyama Tomoko, Tamura Kenji, Kawasaki Shuji, Suzuki Takashi, Murakami Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 511 Issue: 3 Pages: 544-550
- DOI
  10.1016/j.bbrc.2019.02.086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05993, KAKENHI-PLANNED-16H06576
[Journal Article] Quantitative Analysis of Interaction Between CADM1 and Its Binding Cell-Surface Proteins Using Surface Plasmon Resonance Imaging2018
- Author(s)
  Ito Takeshi, Kasai Yutaka, Kumagai Yuki, Suzuki Daisuke, Ochiai-Noguchi Misaki, Irikura Daisuke, Miyake Shiro, Murakami Yoshinori
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 6 Pages: 86-86
- DOI
  10.3389/fcell.2018.00086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05993, KAKENHI-PROJECT-16K18412
[Journal Article] Mathematical modeling and analysis of ErbB3 and EGFR dimerization process for the gefitinib resistance2018
- Author(s)
  Itano Keiko, Ito Takeshi, Kawasaki Shuji, Murakami Yoshinori, Suzuki Takashi
- Journal Title
  
  JSIAM Letters
  
  Volume: 10 Issue: 0 Pages: 33-36
- DOI
  10.14495/jsiaml.10.33
- NAID
  130007431148
- ISSN
  1883-0609, 1883-0617
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05993, KAKENHI-PLANNED-17H06330
[Patent] VSIG4とSiglec-7との分子間相互作用に対する抗VSIG4、抗Siglec-7阻害2023
- Inventor(s)
  伊東剛、村上善則
- Industrial Property Rights Holder
  伊東剛、村上善則
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] マウスモデルを用いた細胞接着分子CADM1による小細胞肺がん悪性化機構の解析2024
- Author(s)
  河原舞理恵、舩城桐子、富永みずき、坂本毅治、伊東剛、村上善則
- Organizer
  2023先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] IGSF3は血管内皮細胞との接着を促進して悪性黒色腫の肺転移を引き起こす2023
- Author(s)
  伊東剛、郭悦、村上善則
- Organizer
  第32回日本がん転移学会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1はRB経路を介してオートファジーを減弱し肺腺がんを抑制する2023
- Author(s)
  伊東剛、永田政義、聶嘉良、松原大祐、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Siglec-7はVSIG4に対する抑制性受容体であり、NK細胞の免疫チェックポイントを制御する2023
- Author(s)
  小宮みこ、水澤舞、坪井裕見、笠井優、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] 遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析2023
- Author(s)
  河原舞理恵、舩城桐子、富永みずき、坂本毅治、伊東剛、村上善則
- Organizer
  第32回日本がん転移学会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] IGSF3のトランスホモ相互作用は血管内皮への接着を促進することでメラノーマの転移を引き起こす2023
- Author(s)
  郭悦、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Siglec-7はVSIG4に対する抑制性受容体であり、NK細胞の免疫チェックポイントを制御する2023
- Author(s)
  小宮みこ、笠井優、伊東剛、村上善則。
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] IGSF3は血管内皮細胞との接着を促進して悪性黒色腫の肺転移を引き起こす2023
- Author(s)
  伊東剛、郭悦、村上善則
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] IgSF3はメラノーマの血管内皮細胞とのホモ結合性の細胞接着を介してメラノーマの肺転移を促進する細胞接着分子である。2023
- Author(s)
  郭悦、笠井優、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium2023
- Author(s)
  Yutaka Kasai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami
- Organizer
  25th International Charles Heidelberger Symposium on Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] T細胞リンパ腫と血管内皮細胞間における細胞接着分子CADM1のトランス・ホモフィリック結合は臓器浸潤を促進する。2023
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則。
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析2023
- Author(s)
  河原舞理恵、舩城桐子、富永みずき、坂本毅治、伊東剛、村上善則
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] CADM1 is a serum marker for small-cell lung cancer associated with poor prognosis and metastasis.2023
- Author(s)
  Murakami Y, Ito T, Funaki T, Iwanari H, Mitani A, Tanaka G, Hamakubo T, Nagase T.
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析2023
- Author(s)
  河原舞理恵、舩城桐子、富永みずき、坂本毅治、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] マウスモデルを用いた細胞接着分子CADM1による小細胞肺がん悪性化機構の解析2023
- Author(s)
  河原舞理恵、舩城桐子、富永みずき、坂本毅治、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] T細胞リンパ腫と血管内皮細胞間における細胞接着分子CADM1のトランス・ホモフィリック結合は臓器浸潤を促進する2023
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1 is a serum marker for small-cell lung cancer associated with poor prognosis and metastasis2023
- Author(s)
  Takeshi Ito, Toko Funaki, Hiroko Iwanari, Goh Tanaka, Takahide Nagase, Takao Hamakubo, Yoshinori Murakami
- Organizer
  American Association for Cancer Research Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] CADM1 is a serum marker and a potential therapeutic target for small-cell lung cancer. American Association for Cancer Research,2023
- Author(s)
  Ito T, Funaki T, Iwanari H, Mitani A, Tanaka G, Hamakubo T, Nagase T、Murakami Y.
- Organizer
  Annual Meeting of the American Association for Cancer Research 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Siglec-7 is an inhibitory receptor for VSIG4 that regulates an immune checkpoint in NK cells2023
- Author(s)
  Miko Komiya, Mai Mizusawa, Yumi Tsuboi, Yutaka Kasai, Yoshinori Murakami, Takeshi Ito
- Organizer
  25th International Charles Heidelberger Symposium on Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] CADM1 is a serum marker for small-cell lung cancer associated with poor prognosis and metastasis.2023
- Author(s)
  Ito T, Funaki T, Iwanari H, Mitani A, Tanaka G, Hamakubo T, Nagase T, Murakami Y.
- Organizer
  The 82nd Annaul Meeting of the Japanese Cancer Assolciation
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1遺伝子の選択的スプライシング制御機構の解析2022
- Author(s)
  篠原優弥、坪井裕見、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] ヘキソサミン生合成経路の数理的解析2022
- Author(s)
  坂本智彦、伊東剛、板野直樹
- Organizer
  日本応用数理学会第18回研究部会連合発表会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] NFATはフィードバック調節因子を介して核細胞質間で減衰振動する2022
- Author(s)
  小宮みこ、伊東剛、村松昌、下地北斗、宮村優里、西山功一、鈴木貴、南敬
- Organizer
  2022年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Analysis of the role of CADM1 in malignant progression of small-cell lung cancer using Rb1/Trp53-floxed mouse model2022
- Author(s)
  富永みずき、舩城桐子、坂本毅治、伊東剛、村上善則
- Organizer
  2021年度文部科学省新学術領域研究学術研究支援基盤形成【先端動物モデル動物支援プラットフォーム】成果発表会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] NFAT indicates nucleocytoplasmic damped oscillation via its feedback modulator2022
- Author(s)
  伊東剛
- Organizer
  新学術領域研究細胞社会ダイバーシティの統合的解明と制御第4回若手ワークショップ
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] NFAT indicates nucleocytoplasmic damped oscillation in vascular endothelial cells via its feedback modulation2022
- Author(s)
  Komiya M, Ito T, Muramatsu M, Miyamura Y, Nishiyama K, Suzuki T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 肺腺がんのMET増幅型EGFR-TKI耐性における役割の数理的解析2022
- Author(s)
  伊東剛、鈴木貴、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] 細胞接着分子CADM1の可溶性断片は小細胞肺がんの血清診断マーカーとなり得る2022
- Author(s)
  伊東剛、松原大祐、舩城桐子、田村研治、長瀬隆英、村上善則
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] 転写因子NFATはフィードバック因子の働きにより血管内皮細胞の核細胞質間で減衰振動する2022
- Author(s)
  小宮みこ、伊東剛、村松昌、宮村優里、西山功一、鈴木貴、南敬
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Trans@homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium2022
- Author(s)
  Kasai Y, Sakamoto T, Ito T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 免疫グロブリンスーパーファミリー分子群のタンパク質ライブラリーを用いた新規免疫チェックポイント分子の探索2022
- Author(s)
  水澤舞、東侑生、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] がん－間質細胞相互作用を介してマウスメラノーマ細胞の転移を促進するIgSF分子の同定2022
- Author(s)
  郭悦、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Analysis of the tumor suppressor function of CADM1 in a mouse model of lung adenocarcinoma2022
- Author(s)
  Sho K, Ito A, Nagata M, Matsubara D, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Magnetic resonance system enables measurement of the number of lung tumors over time in a mouse2022
- Author(s)
  Akashi K, Ito T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Identification of IgSF molecules that promote lung metastasis of mouse melanoma cells through cancer and stromal interactions by comprehensive screening of gene expression2022
- Author(s)
  Yue Guo, Takeshi Ito, Yoshinori Murakami
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] ヘキソサミン生合成経路の数理的解析2022
- Author(s)
  坂本智彦、伊東剛、板野直樹
- Organizer
  日本応用数理学会第18回研究部会連合発表会
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] Mechanical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification2022
- Author(s)
  Ito T, Suzuki T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Analysis of the role of CADM1 in malignant progression of small-cell lung cancer using Rb1/Trp53-floxed mouse models2022
- Author(s)
  Tominaga M, Funaki T, Ito T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] MRIを用いた同一マウスでの経時的な肺腫瘍数の計測2022
- Author(s)
  明石健、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] T細胞リンパ腫と血管内皮細胞間における細胞接着分子CADM1のトランス・ホモ結合は臓器浸潤を促進する2022
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Analysis of the regulatory mechanism of alternative splicing of the CADM1 gene2022
- Author(s)
  Shinohara Y, Tsuboi Y, Ito T, Murakami Y
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] Rb1/Trp53遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析2022
- Author(s)
  富永みずき、舩城桐子、伊東剛、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] The identification of novel immune checkpoint molecules using a protein library of the immunoglobulin superfamily molecules2022
- Author(s)
  Mai Mizusawa, Yuki Azuma, Takeshi Ito, Yoshinori Murakami
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Y, Murakami Y
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 肺腺がんモデルマウスにおける細胞接着分子CADM1の腫瘍抑制能の解析2022
- Author(s)
  聶嘉良、伊東剛、永田政義、松原大祐、村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] CADM1 promotes organ infiltration of adult T-cell leukemia/lymphoma (ATL) cells.2021
- Author(s)
  Yutaka Kasai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-20K21539
[Presentation] 細胞接着分子CADM1は成人T細胞白血病/リンパ腫 (ATL) 細胞の臓器浸潤を促進する2021
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] 細胞接着分子CADM1は小細胞肺がんの増殖及び転移を促進する2021
- Author(s)
  伊東剛、舩城桐子、種井善一、仁木利郎、松原大祐、村上善則
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] CADM1 promotes organ infiltration of adult T-cell leukemia/lymphoma (ATL) cells.2021
- Author(s)
  Yutaka Kasai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1スプライシングバリアントの細胞外領域断片は小細胞肺がんの血清マーカーとなり得る2021
- Author(s)
  伊東剛、松原大祐、舩城桐子、田村研治、長瀬隆英、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Development of a novel serum marker for detecting small cell lung cancer by targeting a Cell Adhesion Molecule 1 (CADM1).2021
- Author(s)
  Ito T, Funaki T, Iwanari H, Tanaka G, Nagase T, Hamakubo T, Murakami Y. Development of a novel serum marker for detecting small cell lung cancer by targeting a Cell Adhesion Molecule 1 (CADM1).
- Organizer
  2020 Annual Meeting of the American Association for Cancer Research.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1 promotes malignant features of small-cell lung cancer by recruiting 4.1R to the plasma membrane.2021
- Author(s)
  Toko Funaki, Takeshi Ito, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-20K21539
[Presentation] 細胞接着分子CADM1は小細胞肺がんの増殖及び転移を促進する2021
- Author(s)
  伊東剛、舩城桐子、種井善一、仁木利郎、松原大祐、村上善則
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] 細胞接着分子CADM1は4.1Rを介して小細胞肺がんの悪性化を促進する2021
- Author(s)
  舩城桐子、伊東剛、後藤明輝、仁木利郎、松原大祐、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] Rb1/Trp53遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析2021
- Author(s)
  富永みずき、舩城桐子、坂本毅治、伊東剛、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] 細胞接着分子CADM1は成人T細胞白血病/リンパ腫 (ATL) 細胞の臓器浸潤を促進する2021
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] The extracellular fragments of a CADM1 variant isoform can be a serum marker for small-cell lung cancer.2021
- Author(s)
  Takeshi Ito, Daisuke Matsubara, Toko Funaki, Kenji Tamura, Takahide Nagase, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-20K21539
[Presentation] 肺腺がんのMET増幅依存的ゲフィチニブ耐性の数理モデルを用いた解析2021
- Author(s)
  伊東剛
- Organizer
  大阪大学数理・データ科学教育研究センター主催講演会：医学研究における数理的方法
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] NFATはフィードバック調節を受けて核細胞質間で減衰振動する2021
- Author(s)
  小宮みこ、伊東剛、村松昌、下地北斗、宮村優里、西山功一、鈴木貴、南敬
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] Novel mechanisms of EGFR-TKI resistance and clonal evolution of lung adenocarcinoma by over expression of a cell adhesion molecule, CADM1.2021
- Author(s)
  Tsuchiya T, Kuwano H, Ito T, Nagata M, Kawai T, Matsubara D, Okamoto I, Tamura K, Nakajima J, Oba M, Murakami Y.
- Organizer
  AACR Special Conference, Tumor Heterogeneity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] CADM1 promotes malignant features of small-cell lung cancer by recruiting 4.1R to the plasma membrane.2021
- Author(s)
  Toko Funaki, Takeshi Ito, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] マウスメラノーマ細胞の肺転移に関与するIgSF分子を介した癌―間質相互作用のスクリーニング2021
- Author(s)
  郭悦、伊東剛、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] マウスメラノーマ細胞の肺転移に関与するIgSF分子を介した癌―間質相互作用のスクリーニング2021
- Author(s)
  郭悦、伊東剛、村上善則
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] NFATはフィードバック調節を受けて核細胞質間で減衰振動する2021
- Author(s)
  小宮みこ、伊東剛、村松昌、下地北斗、宮村優里、西山功一、鈴木貴、南敬
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07091
[Presentation] The extracellular fragments of a CADM1 variant isoform can be a serum marker for small-cell lung cancer.2021
- Author(s)
  Takeshi Ito, Daisuke Matsubara, Toko Funaki, Kenji Tamura, Takahide Nagase, Yoshinori Murakami.
- Organizer
  The 80th Annual Meeting of Japanese Cancer Association,
- Data Source
  KAKENHI-PROJECT-20H03525
[Presentation] 成人T細胞白血病/リンパ腫細胞の臓器浸潤における細胞接着分子CADM1の役割2020
- Author(s)
  笠井優、伊東剛、村上善則
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] Development of a novel serum marker for detecting small cell lung cancer by targeting a Cell Adhesion Molecule 1 (CADM1).2020
- Author(s)
  Ito T, Funaki T, Iwanari H, Tanaka G, Nagase T, Hamakubo T, Murakami Y.
- Organizer
  2020 Annual Meeting of the American Association for Cancer Research.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21539
[Presentation] 細胞接着分子CADM1は小細胞肺がんの増殖・転移を促進する2020
- Author(s)
  伊東剛、舩城桐子、種井善一、松原大祐、村上善則
- Organizer
  第29回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] 細胞接着分子CADM1の発現欠如は肺腺がんの発生および浸潤を促進する2020
- Author(s)
  伊東剛、永田政義、川合剛人、伊藤彰彦、後藤明輝、松原大祐、村上善則
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] CADM1 enhances malignant features of small-cell lung cacner2020
- Author(s)
  伊東剛、舩城桐子、種井善一、村上善則
- Organizer
  第1回日本癌学会若手の会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification2020
- Author(s)
  Takeshi Ito、Yuki Kumagai、Keiko Itano、Tomoko Maruyama、Kenji Tamura、Shuji Kawasaki、Takashi Suzuki、Yoshinori Murakami
- Organizer
  Meeting of JSPS Core-to-Core Program "Establishing International Research Network of Mathematical Oncology": Fusion of Mathematics and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] 免疫グロブリンスーパーファミリー分子群のタンパク質ライブラリーを用いた新規免疫チェックポイント分子の網羅的探索2020
- Author(s)
  東侑生、笠井優、坪井裕見、伊東剛、村上善則
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] Mathematical analysis of endothelial activation controlled by NFAT-DSCR-1 signal axis2020
- Author(s)
  Masashi Muramatsu、Takeshi Ito、Takashi Suzuki、Takashi Minami
- Organizer
  Meeting of JSPS Core-to-Core Program "Establishing International Research Network of Mathematical Oncology": Fusion of Mathematics and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05028
[Presentation] 小細胞肺がんの悪性化における細胞接着因子CADM1の機能解析2020
- Author(s)
  舩城桐子、村上善則、伊東剛
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] Novel mechanisms of EGFR-TKI resistance and clonal evolution of lung adenocarcinoma by over expression of a cell adhesion molecule, CADM1.2020
- Author(s)
  Tsuchiya T, Kuwano H, Ito T, Nagata M, Kawai T, Matsubara D, Okamoto I, Tamura K, Nakajima J, Oba M, Murakami Y.
- Organizer
  AACR Special Conference, Tumor Heterogeneity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21539
[Presentation] Development of a novel tumor marker for small cell lung cancer by targeting a splicing variant of CADM12020
- Author(s)
  伊東剛、岩成宏子、丸山智子、高見和孝、田中剛、長瀬隆英、浜窪隆雄、村上善則
- Organizer
  第5回AMEDがん若手研究者ワークショップ
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] CADM1 enhances extravasation of adult T-cell leukemia cells2019
- Author(s)
  Takeshi Ito, Yutaka Kasai, Siew Pey Gan, Yuki Kumagai, Yoshinori Murakami
- Organizer
  Keystone Symposia, Cancer Metastasis: The Role of Metabolism, Immunity, and the Microenvironment
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] 細胞接着分子CADM1は成人T細胞白血病/リンパ腫細胞の臓器浸潤を促進する2019
- Author(s)
  笠井優、伊東剛、村上善則
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] 小細胞肺がんの悪性化における細胞接着分子CADM1の機能解析2019
- Author(s)
  舩城桐子、伊東剛、村上善則
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] 細胞接着分子CADM1は成人T細胞白血病の浸潤を促進する2019
- Author(s)
  伊東剛、笠井優、顔暁珮、熊谷友紀、村上善則
- Organizer
  第28回日本がん転移学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] 細胞接着分子CADM1は肺腺がんにおいてMST-LATS kinase群と相互作用しHippo経路を制御する2019
- Author(s)
  伊東剛、松原大祐、田中一大、坪井裕見、高井大哉、深山正久、関戸好孝、仁木利郎、村上善則
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16708
[Presentation] Mathematical modeling of gefitinib resistance of lung adenocarcinoma caused by MET amplification2018
- Author(s)
  Takeshi Ito, Yuki Ohashi-Kumagai, Keiko Itano, Shuji Kawasaki, Takashi Suzuki, Yoshinori Murakami
- Organizer
  The 2018 Core-to-Core Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] 肺腺がんにおけるHippo経路の細胞接着分子CADM1による制御2018
- Author(s)
  中村敦子、伊東剛、田中一大、中島淳、森川鉄平、深山正久、関戸好孝、仁木利郎、松原大祐、村上善則
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K18412
[Presentation] 肺腺がんのMET増幅依存的ゲフィチニブ耐性の数理モデルを用いた解析2018
- Author(s)
  伊東剛、熊谷友紀、板野景子、川崎秀二、鈴木貴、村上善則
- Organizer
  第27回日本がん転移学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] CADM1は成人T細胞白血病の血管外遊出を促進する2018
- Author(s)
  伊東剛、熊谷友紀、村上善則
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] 表面プラズモン共鳴イメージングを利用した細胞表面分子間相互作用のスクリーニング2017
- Author(s)
  笠井優、伊東剛、大橋（熊谷）友紀、鈴木大輔、入倉大祐、三宅司郎、村上善則
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K18412
[Presentation] 肺腺がんのMET増幅型ゲフィチニブ耐性の数理モデルを用いた解析2017
- Author(s)
  伊東剛、大橋（熊谷）友紀、板野景子、川崎秀二、鈴木貴、村上善則
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] 肺腺がんのMET増幅型ゲフィチニブ耐性の数理モデルを用いた解析2017
- Author(s)
  伊東剛、板野景子、鈴木貴、村上善則
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] 肺腺がんのMET増幅型ゲフィチニブ耐性の数理モデルを用いた解析2017
- Author(s)
  伊東剛、大橋（熊谷）友紀、板野景子、川崎秀二、鈴木貴、村上善則
- Organizer
  新学術領域研究「数理シグナル」第１回若手ワークショップ
- Data Source
  KAKENHI-PUBLICLY-17H05993
[Presentation] Hippoシグナル経路の制御における細胞接着分子CADM1の関与2016
- Author(s)
  中村敦子、伊東剛、大場基、松原大祐、村上善則
- Organizer
  平成28年度新学術領域研究　先端モデル動物支援プラットフォーム　若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-16K18412
[Presentation] Hippoシグナル経路の制御における細胞接着分子CADM1の関与2016
- Author(s)
  中村敦子、伊東剛、大場基、松原大祐、村上善則
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K18412

1. Murakami Yoshinori (30182108)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
2. Matsubara Daisuke (80415554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 冨谷智明 (90227637)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 武田憲彦 (40422307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 柴綾 (50708427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. MOGUSHI Kaoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 笠井優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 家城博隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 畠山昌則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 南敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Takeshi 伊東 剛

Research Projects

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Co-Researchers

VSIG4を標的とした免疫チェックポイント阻害療法の確立Principal Investigator

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Elucidation of carcinogenesis, metastasis and metabolic mechanisms in HNF4A-positive lung tumor

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Analysis of the molecular mechanism underlying CADM1-induced growth and metastasis of small-cell lung cancerPrincipal Investigator

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Development of novel intervening approaches to cancer progression by comprehensive analyses of interactions between cell adhesion molecules

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Mathematical analysis of cancer metastasis focused on cancer cell-endothelial cell interactionsPrincipal Investigator

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Development of novel diagnostic and therapeutic approaches to cancer by analyzing specific features of the immunoglobulin superfamily of molecules.

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Identification of trans-interacting receptors for CADM1Principal Investigator

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肺腺がんのゲフィチニブ耐性機構における細胞接着分子CADM1の役割の数理的解明Principal Investigator

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Involvement of CADM1 in the regulation of Hippo pathwayPrincipal Investigator

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[Journal Article] Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC.2024

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[Journal Article] <scp>IGSF3</scp> is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium2024

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[Journal Article] Histologic transformation of non‐small‐cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms2024

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[Journal Article] Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC2024

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[Journal Article] Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features2024

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Ito Takeshi 伊東剛