Fukunaga Ichiro 福永一朗

… Alternative Names

FUKUNAGA Ichiro 福永一朗

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Researcher Number	20746581
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任助教
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 大学院医学研究科, 特任助教 2020 – 2021: 順天堂大学, 大学院医学研究科, 非常勤助教 2017 – 2020: 順天堂大学, 医学(系)研究科(研究院), 助教 2015 – 2016: 順天堂大学, 医学(系)研究科(研究院), 博士研究員
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 52020:Neurology-related / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator GJB2 / 遺伝性難聴 / Connexin26 / iPS細胞 / 内耳細胞 / 鳥類胚 / 分化誘導 / ギャップ結合プラーク / 蝸牛支持細胞 / ヒトiPS細胞 … More / ギャップ結合 / コネキシン26 / 内耳 / ES/iPS細胞 / 有毛細胞 / 蝸牛線維細胞 / 加齢性難聴 … More Except Principal Investigator iPS細胞 / 遺伝性難聴 / 周波数弁別 / 聴毛 / 内耳有毛細胞 / 聴覚 / 遺伝子難聴 / 難聴マウス / 人工多能性幹細胞 / 蝸牛器官培養 / 難聴 / 幹細胞ホーミング / 内耳再生医療 / 蝸牛 / ケモカイン / 移植 / 幹細胞 / ホーミング / 内耳 Less

神経変性疾患を対象とした安全性試験へ適用可能な脳オルガノイドの開発と評価系の構築Principal Investigator
- Principal Investigator
  
  福永一朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Juntendo University
generation of inner ear supporting cells from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  Fukunaga Ichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
Hair bundle formation and tonotopy in genetic hearing loss models and the iPS cells
- Principal Investigator
  
  kamiya kazusaku
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
generation of functional CX26 gap junction forming cell derived from mouse iPS cells and its application to hereditary deafnessPrincipal Investigator
- Principal Investigator
  
  Fukunaga Ichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Stem cell homing for inner ear cell therapy with iPS cell
- Principal Investigator
  
  KAMIYA Kazusaku
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Generation of inner ear cells from mouse iPS cells and its application to Age-related hearing lossPrincipal Investigator
- Principal Investigator
  
  FUKUNAGA Ichiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University

All 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Generation of two iPSC lines from siblings of a homozygous patient with hearing loss and a heterozygous carrier with normal hearing carrying p.G45E/Y136X mutation in GJB22021
- Author(s)
  Fukunaga Ichiro、Oe Yoko、Danzaki Keiko、Ohta Sayaka、Chen Cheng、Iizumi Madoka、Shiga Takahiro、Matsuoka Rina、Anzai Takashi、Hibiya-Motegi Remi、Tajima Shori、Ikeda Katsuhisa、Akamatsu Wado、Kamiya Kazusaku
- Journal Title
  
  Stem Cell Research
  
  Volume: 53 Pages: 102290-102290
- DOI
  10.1016/j.scr.2021.102290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09387, KAKENHI-PROJECT-20K21662, KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-19K16930, KAKENHI-PROJECT-18H02953, KAKENHI-PROJECT-21H03089, KAKENHI-PROJECT-21K07301, KAKENHI-PROJECT-21K09617, KAKENHI-PROJECT-18K16857, KAKENHI-PROJECT-18K16905
[Journal Article] Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells2021
- Author(s)
  Ichiro Fukunaga, Yoko Oe, Cheng Chen, Keiko Danzaki, Sayaka Ohta, Akito Koike, Katsuhisa Ikeda, Kazusaku Kamiya
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 21 Pages: 1-12
- DOI
  10.3389/fcell.2021.602197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-18H02953, KAKENHI-PROJECT-21H03089, KAKENHI-PROJECT-21K09617, KAKENHI-PROJECT-20K21662
[Journal Article] Modeling Gap junction beta 2 gene-related deafness with human iPS2021
- Author(s)
  Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Kyoko Shirai, Atsushi Kawano, Katsuhisa Ikeda, Kazusaku Kamiya
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 15 Pages: 1429-1442
- DOI
  10.1093/hmg/ddab097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-18H02953, KAKENHI-PROJECT-21H03089, KAKENHI-PROJECT-21K09617, KAKENHI-PROJECT-20K21662
[Journal Article] Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation.2020
- Author(s)
  Fukunaga I, Shiga T, Chen C, Oe Y, Danzaki K, Ohta S, Matsuoka R, Anzai T, Hibiya-Motegi R, Tajima S, Ikeda K, Akamatsu W, Kamiya K.
- Journal Title
  
  Stem Cell Research
  
  Volume: 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02953
[Journal Article] Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation2020
- Author(s)
  Fukunaga Ichiro、Shiga Takahiro、Chen Cheng、Oe Yoko、Danzaki Keiko、Ohta Sayaka、Matsuoka Rina、Anzai Takashi、Hibiya-Motegi Remi、Tajima Shori、Ikeda Katsuhisa、Akamatsu Wado、Kamiya Kazusaku
- Journal Title
  
  Stem Cell Research
  
  Volume: 43 Pages: 101674-101674
- DOI
  10.1016/j.scr.2019.101674
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-18K16857, KAKENHI-PROJECT-18K16905, KAKENHI-PROJECT-19K16930, KAKENHI-PROJECT-18H02953
[Journal Article] Generation of two induced pluripotent stem cell lines from PBMCs of siblings carrying c.235delC mutation in the GJB2 gene associated with sensorineural hearing loss2020
- Author(s)
  Fukunaga Ichiro、Shirai Kyoko、Oe Yoko、Danzaki Keiko、Ohta Sayaka、Shiga Takahiro、Chen Cheng、Ikeda Katsuhisa、Akamatsu Wado、Kawano Atsushi、Kamiya Kazusaku
- Journal Title
  
  Stem Cell Research
  
  Volume: 47 Pages: 101910-101910
- DOI
  10.1016/j.scr.2020.101910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09387, KAKENHI-PROJECT-20K21662, KAKENHI-PROJECT-19K16930, KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-18H02953
[Journal Article] Generation of Functional CX26-Gap-Junction-Plaque-Forming Cells with Spontaneous Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.2019
- Author(s)
  Fukunaga I, Fujimoto A, Hatakeyama K, Kurebayashi N, Ikeda K, Kamiya K.
- Journal Title
  
  Current Protocols in Stem Cell Biology
  
  Volume: 51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02953
[Journal Article] Generation of Functional CX26?Gap‐Junction‐Plaque‐Forming Cells with Spontaneous Ca 2+ Transients via a Gap Junction Characteristic of Developing Cochlea2019
- Author(s)
  Fukunaga Ichiro、Fujimoto Ayumi、Hatakeyama Kaori、Kurebayashi Nagomi、Ikeda Katsuhisa、Kamiya Kazusaku
- Journal Title
  
  Current Protocols in Stem Cell Biology
  
  Volume: 51 Issue: 1
- DOI
  10.1002/cpsc.100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09914, KAKENHI-PROJECT-17K16948, KAKENHI-PROJECT-18H02953
[Journal Article] In vitro models of GJB2-related hearing loss recapitulate Ca2+ transients via a gap junction characteristic of developing cochlea.2016
- Author(s)
  Ichiro Fukunaga, Ayumi Fujimoto, Kaori Hatakeyama, Toru Aoki, Atena Nishikawa, Tetsuo Noda, Osamu Minowa, Nagomi Kurebayashi, Katsuhisa Ikeda, Kazusaku Kamiya.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 7 Issue: 6 Pages: 1023-1036
- DOI
  10.1016/j.stemcr.2016.10.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20229
[Journal Article] Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice.2015
- Author(s)
  Anzai, T., Fukunaga, I., Hatakeyama, K., Fujimoto, A., Kobayashi, K., Nishikawa, A., Aoki, T., Noda, T., Minowa, O., Ikeda, K., and Kamiya, K
- Journal Title
  
  PloS one
  
  Volume: 10 Issue: 10 Pages: e0141258-e0141258
- DOI
  10.1371/journal.pone.0141258
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-15K20229, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25293351
[Journal Article] Connexin26 regulates assembly and maintenance of cochlear gap junction macromolecular complex for normal hearing2015
- Author(s)
  Kazusaku Kamiya, Ichiro Fukunaga, Kaori Hatakeyama and Katsuhisa Ikeda
- Journal Title
  
  AIP Conference Proceedings
  
  Volume: 1703 Pages: 030018-030018
- DOI
  10.1063/1.4939333
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-15K20229, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25293351
[Patent] 内耳前駆細胞の作製法2021
- Inventor(s)
  福永一朗, 神谷和作
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K09914
[Patent] 内耳細胞の製造法2017
- Inventor(s)
  神谷和作, 福永一朗
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-22
- Overseas
- Data Source
  KAKENHI-PROJECT-15K20229
[Patent] 内耳前駆細胞の製造法2016
- Inventor(s)
  神谷和作, 福永一朗
- Industrial Property Rights Holder
  学校法人　順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2016-02-22
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] SFEBq培養におけるConnexin26を指標とした培養条件の検討と内耳細胞への分化誘導2020
- Author(s)
  福永一朗
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K09914
[Presentation] ES細胞の3次元培養におけるコネキシン26を高発現する条件の検討と内耳細胞への分化誘導2019
- Author(s)
  福永一朗
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] Generation of inner ear Cx26-gap junction plaque forming cells derived from induced pluripotent stem cells2018
- Author(s)
  Ichiro Fukunaga
- Organizer
  Association for Research in Otolaryngology
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] Generation of Stem Cell derived inner ear Connexin 26 gap junction plaque forming cells2018
- Author(s)
  Ichiro Fukunaga
- Organizer
  Inner Ear Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] iPS細胞から機能性を有するConnexin26ギャップ結合プラークを構築する内耳細胞への分化誘導2018
- Author(s)
  福永一朗
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] iPS細胞から機能性を持ったConnexin26ギャップ結合を構築する細胞への分化誘導2017
- Author(s)
  福永一朗
- Organizer
  第27回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] Generation of functional Cx26-gap junction plaque forming cells that exhibit spontaneous Ca2+ transients from induced pluripotent stem cells.2017
- Author(s)
  Ichiro Fukunaga
- Organizer
  Inner Ear Biology, 54th Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16948
[Presentation] iPS細胞からConnexin26ギャップ結合プラークを構築する細胞への分化誘導.2017
- Author(s)
  福永一朗, 畠山佳欧里, 青木徹, 藤本あゆみ, 西川貴菜, 美野輪治, 池田勝久, 神谷和作
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] iPS細胞からのConnexin26発現細胞への分化誘導と細胞間ギャップ結合プラークの構築2016
- Author(s)
  福永一朗、畠山佳欧里、青木徹、藤本あゆみ、西川貴菜、美野輪治、池田勝久、神谷和作
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Induction of iPS cell differetiation into Connexin26 positive cells with gap junction plaques using cochlear feeder cell2016
- Author(s)
  Ayumi Fujimoto, Ichiro Fukunaga, Kaori Hatakeyama, Toru Aoki, Atena Nishikawa, Katsuhisa Ikeda, Kazusaku Kamiya
- Organizer
  Association for Research in Otolaryngology (ARO), 39th Annual MidWinter Meeting
- Place of Presentation
  米国, サンディエゴ
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] コネキシン26欠損マウスからのiPS細胞の樹立2016
- Author(s)
  青木徹、福永一朗、畠山佳欧里、藤本あゆみ、西川貴菜、美野輪治、池田勝久、神谷和作
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] 内耳フィーダー細胞を用いたiPS細胞の分化誘導によるCx26ギャップ結合形成細胞の樹立2016
- Author(s)
  藤本あゆみ、福永一朗、畠山佳欧里、青木徹、西川貴菜、池田勝久、神谷和作
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Generation of Cx26-gap junction plaque forming cell from iPS cell.2016
- Author(s)
  Ichiro Fukunaga, Ayumi Fujimoto, Kaori Hatakeyama, Toru Aoki, Atena Nishikawa, Osamu Minowa, Katsuhisa Ikeda, Kazusaku Kamiya.
- Organizer
  Inner Ear Biology
- Place of Presentation
  Montpellier, France.
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Gene therapy and cell therapy targeting cochlear gap junction formation for GJB2 associated hearing loss.2016
- Author(s)
  Ichiro Fukunaga, Takashi Iizuka, Kaori Hatakeyama, Ayumi Fujimoto, Osamu Minowa, Katsuhisa Ikeda, Kazusaku Kamiya.
- Organizer
  Inner Ear Biology
- Place of Presentation
  Montpellier, France.
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Differentiation of mouse iPS cell into Cx26-positive cell and formation of inter cellular Cx26-gap junction plaque2016
- Author(s)
  Ichiro Fukunaga, Kaori Hatakeyama,Toru Aoki, Ayumi Fujimoto, Atena Nishikawa,Katsuhisa Ikeda, Kazusaku Kamiya
- Organizer
  Association for Research in Otolaryngology (ARO), 39th Annual MidWinter Meeting
- Place of Presentation
  米国, サンディエゴ
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Cochlear gap junction plaque, stabilized macromolecular complex composed of specific connexins2015
- Author(s)
  Kazusaku Kamiya, Ichiro Fukunaga, Kaori Hatakeyama, Toru Aoki, Ayumi Fujimoto, Atena Nishikawa ,Takashi Anzai, Osamu Minowa, Katsuhisa Ikeda
- Organizer
  52nd Inner Ear Biology Workshop
- Place of Presentation
  イタリア,ローマ
- Year and Date
  2015-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229
[Presentation] Differentiation of mouse iPS cell into Cx26-positive cell and formation of inter cellular Cx26-gap junction plaque2015
- Author(s)
  Ichiro Fukunaga, Kaori Hatakeyama,Toru Aoki, Atena Nishikawa, Ayumi Fujimoto, Osamu Minowa, Katsuhisa Ikeda, Kazusaku Kamiya
- Organizer
  52nd Inner Ear Biology Workshop
- Place of Presentation
  イタリア,ローマ
- Year and Date
  2015-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20229

1. KAMIYA Kazusaku (10374159)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. 小池卓二 (10282097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 安齋崇 (20624852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 池田勝久 (70159614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MINOWA Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUZIMOTO Ayumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HATAKEYAMA Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fukunaga Ichiro 福永 一朗

FUKUNAGA Ichiro 福永 一朗

Research Projects

Research Products

Co-Researchers

神経変性疾患を対象とした安全性試験へ適用可能な脳オルガノイドの開発と評価系の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

generation of inner ear supporting cells from human iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hair bundle formation and tonotopy in genetic hearing loss models and the iPS cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

generation of functional CX26 gap junction forming cell derived from mouse iPS cells and its application to hereditary deafnessPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stem cell homing for inner ear cell therapy with iPS cell

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of inner ear cells from mouse iPS cells and its application to Age-related hearing lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Generation of two iPSC lines from siblings of a homozygous patient with hearing loss and a heterozygous carrier with normal hearing carrying p.G45E/Y136X mutation in GJB22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modeling Gap junction beta 2 gene-related deafness with human iPS2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation.2020

Author(s)

Journal Title

Data Source

[Journal Article] Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of two induced pluripotent stem cell lines from PBMCs of siblings carrying c.235delC mutation in the GJB2 gene associated with sensorineural hearing loss2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of Functional CX26-Gap-Junction-Plaque-Forming Cells with Spontaneous Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.2019

Author(s)

Journal Title

Data Source

[Journal Article] Generation of Functional CX26?Gap‐Junction‐Plaque‐Forming Cells with Spontaneous Ca 2+ Transients via a Gap Junction Characteristic of Developing Cochlea2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro models of GJB2-related hearing loss recapitulate Ca2+ transients via a gap junction characteristic of developing cochlea.2016

Fukunaga Ichiro 福永一朗

FUKUNAGA Ichiro 福永一朗