KON AYANA 昆彩奈

… Alternative Names

Kon Ayana 昆彩奈

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Researcher Number	20772403
Other IDs
Affiliation (Current)	2025: 東京大学, 医科学研究所, 准教授 2025: 京都大学, 医学研究科, 特定講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医学研究科, 特定講師 2018 – 2022: 京都大学, 医学研究科, 助教 2016 – 2017: 京都大学, 医学研究科, 特定助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Medium-sized Section 50:Oncology and related fields / Broad Section I / Biological Sciences
Keywords	Principal Investigator 急性骨髄性白血病 / 骨髄異形成症候群 / クローン進化 / マウスモデル / DDX41遺伝子 / 胚細胞変異 / 白血病幹細胞 / スプライシング因子 / RCAS/TVAシステム / 遺伝子変異 / DDX41 / 新規遺伝子変異 / 遺伝子改変マウス … More Except Principal Investigator … More クローン進化 / 単一細胞シーケンス / 白血病 / 遺伝子変異 / 腫瘍学 / オルガノイド / 全ゲノムシーケンス / 腫瘍生物学 / ゲノム生物学 / 染色体立体構造解析 / 染色体動態 / 染色体構造 / ゲノム情報 / エピゲノム / 染色体高次構造 / Hi-C法 Less

胚細胞変異と後天的ゲノム異常の協調による先天性骨髄系腫瘍の分子病態の解明Principal Investigator
- Principal Investigator
  
  昆彩奈
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Elucidating the mechanisms of clonal evolution of myeloid neoplasms with germline predispositionPrincipal Investigator
- Principal Investigator
  
  Kon Ayana
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Elucidating the contribution of the order of mutation acquisition to the clonal evolution of cancer using single-cell sequencing
- Principal Investigator
  
  Ogawa Seishi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.
- Principal Investigator
  
  Ogawa Seishi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyoto University
Elucidating the molecular mechanisms underlying the clonal evolution of leukemic stem cellsPrincipal Investigator
- Principal Investigator
  
  Kon Ayana
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasmsPrincipal Investigator
- Principal Investigator
  
  Kon Ayana
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Computational reconstruction of the higher-order structure of chromosomes and linkage analysis between chromosome structure and phenotype
- Principal Investigator
  
  Itoh Takehiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Germ line DDX41 mutations define a unique subtype of myeloid neoplasms2023
- Author(s)
 Makishima H, Saiki R, Nannya Y, (17人省略), Kon A, (28人省略), Maciejewski JP, Ogawa S.
- Journal Title
 
 Blood
 
 Volume: 141 Issue: 5 Pages: 534-549
- DOI
 10.1182/blood.2022018221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K08480, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
[Journal Article] SETBP1 is dispensable for normal and malignant hematopoiesis2023
- Author(s)
  Tanaka A, Nishimura K, Saika W, Kon A, Koike Y, Tatsumi H, Takeda J, Nomura M, Zang W, Nakayama M, Matsuda M, Yamazaki H, Fukumoto M, Ito H, Hayashi Y, Kitamura T, Kawamoto H, Takaori-Kondo A, Koseki H, Ogawa S
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 9 Pages: 1802-1811
- DOI
  10.1038/s41375-023-01970-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394, KAKENHI-PLANNED-19H05745
[Journal Article] Identification of an asymptomatic Shwachman-Bodian-Diamond syndrome mutation in a patient with acute myeloid leukemia.2022
- Author(s)
  Shibata S, Inano S, Watanabe M, Fujiwara K, Ueno H, Nannya Y, Kanda J, Kawasaki N, Okamoto Y, Takiuchi Y, Fukunaga A, Tabata S, Ogawa S, Takaori-Kondo A, Kitano T.
- Journal Title
  
  Int J Hematol;115(3)
  
  Volume: - Pages: 428-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] A case of vasoactive intestinal peptide-secreting tumor (VIPoma) arising from MEN1 inactivation which recurred 15 years after the initial resection.2022
- Author(s)
  Sakurai M, Wakabayashi T, Kondo Y, Ikeda E, Watanabe K, Takei A, Okazaki H, Okada K, Ebihara K, Kakiuchi N, Ogawa S, Fukushima N, Ishibashi S.
- Journal Title
  
  Endocr J
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] Successful azacitidine therapy for myelodysplastic syndrome associated with VEXAS syndrome.2022
- Author(s)
  Kataoka A, Mizumoto C, Kanda J, Iwasaki M, Sakurada M, Oka T, Fujimoto M, Yamamoto Y, Yamashita K, Nannya Y, Ogawa S, Takaori-Kondo A.
- Journal Title
  
  Int J Hematol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia2022
- Author(s)
 Takeda J, Kenichi Y, (9人省略), Kon A (12/41番目), (途中省略), Makishima H, Ogawa S
- Journal Title
 
 Blood Cancer Discovery
 
 Volume: 3 Issue: 5 Pages: 410-427
- DOI
 10.1158/2643-3230.bcd-21-0192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
[Journal Article] Tracing the evolutionary history of blood cells to the unicellular ancestor of animals.2022
- Author(s)
  Nagahata Y, Masuda K, Nishimura Y, Ikawa T, Kawaoka S, Kitawaki T, Nanya Y, Ogawa S, Suga H, Satou Y, Takaori-Kondo A, Kawamoto H.
- Journal Title
  
  Blood
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] Identification of an asymptomatic Shwachman Bodian Diamond syndrome mutation in a patient with acute myeloid leukemia2021
- Author(s)
  Shibata Sho、Inano Shojiro、Watanabe Mizuki、Fujiwara Kensuke、Ueno Hiroo、Nannya Yasuhito、Kanda Junya、Kawasaki Naoto、Okamoto Yoshio、Takiuchi Yoko、Fukunaga Akiko、Tabata Sumie、Ogawa Seishi、Takaori-Kondo Akifumi、Kitano Toshiyuki
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 3 Pages: 428-434
- DOI
  10.1007/s12185-021-03251-2
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Journal Article] Next‐generation sequencing in two cases of de novo acute basophilic leukaemia2021
- Author(s)
  Shimizu Takuya、Kondo Tadakazu、Nannya Yasuhito、Watanabe Mizuki、Kitawaki Toshio、Shindo Takero、Hishizawa Masakatsu、Yamashita Kouhei、Ogawa Seishi、Takaori‐Kondo Akifumi
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 25 Issue: 14 Pages: 7095-7099
- DOI
  10.1111/jcmm.16591
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19H05656
[Journal Article] Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.2021
- Author(s)
  Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T. Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K. Saito, Minoru Takata.
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 15 Pages: 2021-2032
- DOI
  10.1182/blood.2020009111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-20H03450, KAKENHI-PUBLICLY-20H05396, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03642, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-21H04719
[Journal Article] A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells2021
- Author(s)
  Yamamoto Keita、Goyama Susumu、Asada Shuhei、Fujino Takeshi、Yonezawa Taishi、Sato Naru、Takeda Reina、Tsuchiya Akiho、Fukuyama Tomofusa、Tanaka Yosuke、Yokoyama Akihiko、Toya Hikaru、Kon Ayana、Nannya Yasuhito、Onoguchi-Mizutani Rena、Nakagawa Shinichi、Hirose Tetsuro、Ogawa Seishi、Akimitsu Nobuyoshi、Kitamura Toshio
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 8 Pages: 109576-109576
- DOI
  10.1016/j.celrep.2021.109576
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05377, KAKENHI-PUBLICLY-21H00274, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H00537, KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-19H03685, KAKENHI-PROJECT-19H03694, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-20K15988, KAKENHI-PLANNED-21H05274
[Journal Article] LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells2020
- Author(s)
  Jo Tomoyasu、Nishikori Momoko、Kogure Yasunori、Arima Hiroshi、Sasaki Katsuhiro、Sasaki Yoshiteru、Nakagawa Tomoko、Iwai Fumie、Momose Shuji、Shiraishi Aki、Kiyonari Hiroshi、Kagaya Noritaka、Onuki Tetsuo、Shin-ya Kazuo、Yoshida Minoru、Kataoka Keisuke、Ogawa Seishi、Iwai Kazuhiro、Takaori-Kondo Akifumi
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 6 Pages: 684-697
- DOI
  10.1182/blood.2019002654
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05499, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17K08880, KAKENHI-PROJECT-18K08324, KAKENHI-ORGANIZER-18H05497
[Journal Article] Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes2020
- Author(s)
  Ochi Y, Ogawa Seishi., et al.
- Journal Title
  
  Cancer Discov
  
  Volume: - Issue: 6 Pages: 836-853
- DOI
  10.1158/2159-8290.cd-19-0982
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245, KAKENHI-INTERNATIONAL-15K21761, KAKENHI-PROJECT-20K21546, KAKENHI-PLANNED-16H06484, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K16084, KAKENHI-PROJECT-19K24694, KAKENHI-PROJECT-19H03694
[Journal Article] The transcription factor E2A activates multiple enhancers that drive Rag expression in developing T and B cells2020
- Author(s)
  Miyazaki Kazuko、Watanabe Hitomi、Yoshikawa Genki、Chen Kenian、Hidaka Reiko、Aitani Yuki、Osawa Kai、Takeda Rie、Ochi Yotaro、Tani-ichi Shizue、Uehata Takuya、Takeuchi Osamu、Ikuta Koichi、Ogawa Seishi、Kondoh Gen、Lin Yin C.、Ogata Hiroyuki、Miyazaki Masaki
- Journal Title
  
  Science Immunology
  
  Volume: 5 Issue: 51 Pages: 1455-1455
- DOI
  10.1126/sciimmunol.abb1455
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03487, KAKENHI-PROJECT-19J13775, KAKENHI-PROJECT-18K15185
[Journal Article] Clonal evolution of myelodysplastic syndromes2020
- Author(s)
  Ayana Kon
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 4 Pages: 358-367
- DOI
  10.11406/rinketsu.61.358
- NAID
  130007839413
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16084
[Journal Article] Clonal evolution of myeloid malignancies2020
- Author(s)
  Ayana Kon
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 9 Pages: 1120-1129
- DOI
  10.11406/rinketsu.61.1120
- NAID
  130007937122
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K16084
[Journal Article] Acute myeloid leukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dose methotrexate therapy for rheumatoid arthritis2019
- Author(s)
  Chonabayashi Kazuhisa、Yoshida Yoshinori、Kitawaki Toshio、Nannya Yasuhito、Nakamura Momoko、Oshima Shinichiro、Hishizawa Masakatsu、Yamashita Kouhei、Ogawa Seishi、Takaori-Kondo Akifumi
- Journal Title
  
  Annals of Hematology
  
  Volume: 98 Issue: 12 Pages: 2841-2843
- DOI
  10.1007/s00277-019-03838-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656
[Journal Article] Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis2019
- Author(s)
  Kakiuchi Nobuyuki et al.
- Journal Title
  
  Nature
  
  Volume: 577 Issue: 7789 Pages: 260-265
- DOI
  10.1038/s41586-019-1856-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K15747, KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-18H05278
[Journal Article] Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences2019
- Author(s)
  Masaki So、Ikeda Shun、Hata Asuka、Shiozawa Yusuke、Kon Ayana、Ogawa Seishi、Suzuki Kenji、Hakuno Fumihiko、Takahashi Shin-Ichiro、Kataoka Naoyuki
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 10 Pages: 1-8
- DOI
  10.3389/fgene.2019.00338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06012, KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H03972
[Journal Article] Molecular pathogenesis of disease progression in MLL-rearranged AML.2018
- Author(s)
  Kotani S, Yoda A, Kon A, Kataoka K, Ochi Y, Shiozawa Y, Hirsch C, Takeda J, Ueno H, Yoshizato T, Yoshida K, Nakagawa MM, Nannya Y, Kakiuchi N, Yamauchi T, Aoki K, Shiraishi Y, Miyano S, Maeda T, Maciejewski JP, Takaori-Kondo A, Ogawa S, Makishima H.
- Journal Title
  
  Leukemia
  
  Volume: 33 Issue: 3 Pages: 612-624
- DOI
  10.1038/s41375-018-0253-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-17H04990, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-17K19595, KAKENHI-PROJECT-19H01053
[Journal Article] A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia2018
- Author(s)
  Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway HE, Sekeres MA, Radivoyevitch T, Yoshida K, Sanada M, Yoshizato T, Kataoka K, Nakagawa MM, Ueno H, Nannya Y, Kon A, Shiozawa Y, Takeda J, Shiraishi Y, Chiba K, Miyano S, Singh J, Padgett RA, Ogawa S, Maciejewski JP, Makishima H
- Journal Title
  
  Leukemia
  
  Volume: 32(3) Issue: 3 Pages: 839-843
- DOI
  10.1038/leu.2017.319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-16K19574, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-17H04990
[Journal Article] PhysiologicalSrsf2P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice2017
- Author(s)
  Kon Ayana、Yamazaki Satoshi、Nannya Yasuhito、Kataoka Keisuke、Ota Yasunori、Nakagawa Masahiro Marshall、Yoshida Kenichi、Shiozawa Yusuke、Morita Maiko、Yoshizato Tetsuichi、Sanada Masashi、Nakayama Manabu、Koseki Haruhiko、Nakauchi Hiromitsu、Ogawa Seishi
- Journal Title
  
  Blood
  
  Volume: 131 Issue: 6 Pages: 621-635
- DOI
  10.1182/blood-2017-01-762393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K19574
[Journal Article] Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia.2017
- Author(s)
  Seki M, Kimura S, Isobe T, Yoshida K, (13 authors), Masuda K, Kawamoto H, Ohki K, Kato M, Arakawa Y, Koh K, Hanada R, Moritake H, Akiyama M, Kobayashi R, Deguchi T, Hashii Y, Imamura T, Sato A, Kiyokawa N, Oka A, Hayashi Y, Takagi M, Manabe A, Ohara A, Horibe K, Sanada M, Iwama A, Mano H, Miyano S, Ogawa S, Takita J
- Journal Title
  
  Nature Genetics
  
  Volume: 49 Issue: 8 Pages: 1274-1281
- DOI
  10.1038/ng.3900
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17K10136, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-17H04234, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-16K15498, KAKENHI-PROJECT-16K19574, KAKENHI-PROJECT-17K16242, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-15H05325
[Journal Article] Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms.2016
- Author(s)
  Mori T, Nagata Y, Makishima H, Sanada M, Shiozawa Y, Kon A, Yoshizato T, Sato-Otsubo A, Kataoka K, Shiraishi Y, Chiba K, Tanaka H, Ishiyama K, Miyawaki S, Mori H, Nakamaki T, Kihara R, Kiyoi H, Koeffler HP, Shih LY, Miyano S, Naoe T, Haferlach C, Kern W, Haferlach T, Ogawa S, Yoshida K.
- Journal Title
  
  Leukemia.
  
  Volume: 30 Issue: 11 Pages: 2270-2273
- DOI
  10.1038/leu.2016.212
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-15H05668, KAKENHI-PROJECT-15J02911, KAKENHI-PROJECT-16K19574
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2024
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Azumi Tomita, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  3rd Regional Symposium on Myelodysplastic Syndromes (MDSR 2024)
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Functional roles of DDX41 mutations in the development of myeloid malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  the 17th International Congress on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  The 13th JSH International Symposium 2023 in Tsukuba
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  65th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  65th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第85回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] DISTINCT PATHOGENESIS OF CLONAL HEMATOPOIESIS REVEALED BY SINGLE-CELL MULTI-OMICS SEQUENCING.2023
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, Masanori Motomura, June Takeda, Xingxing Qi, Koji Okazaki, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  MDS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Functional roles of germline and somatic DDX41 mutations in the pathogenesis of myeloid malignancies2023
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第81回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Functional roles of DDX41 mutations in the development of myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Yotaro Ochi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  27th Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka,Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Functional roles of DDX41 mutations in the development of myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Yotaro Ochi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  27th Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Ryunosuke Saiki, Yotaro Ochi, June Takeda, Zhao Lanying, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第81回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies2022
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka,Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing.2022
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Ryunosuke Saiki, Yotaro Ochi, June Takeda, Zhao Lanying, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The molecular pathogenesis of DDX41-mutated myeloid neoplasms2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Non-cell autonomous effects of mutated cells in the pathogenesis of clonal hematopoiesis.2021
- Author(s)
  Masahiro M Nakagawa12, Ryosaku Inagaki123, Yasuhito Nannya1, Zhao Lanying15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Tetsuichi Yoshizato6, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda4 and Seishi Ogawa156
- Organizer
  The 80th Annual Meeting of the Japanese_Society of_Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method.2021
- Author(s)
  Masahiro M Nakagawa1, Ryosaku Inagaki12, Yutaka Kuroda4, Yasuhito Nannya1, Lanying Zhao15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda3 and Seishi Ogawa145
- Organizer
  63rd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Functional roles of DDX41 mutations in the development of myeloid malignancies2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  63rd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell sequencing.2021
- Author(s)
  Masahiro M Nakagawa12, Ryosaku Inagaki123, Yutaka Kuroda4, Yasuhito Nannya1, Zhao Lanying15, Yotaro Ochi1, June Takeda1, Xingxing Qi1, Akinori Yoda1, Ayana Kon1, Tetsuichi Yoshizato6, Nobuyuki Kakiuchi1, Hideki Makishima1, Shuichi Matsuda4 and Seishi Ogawa156
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Clonal evolution and prognostic impact of mutations in blast crisis of chronic myeloid leukemia2021
- Author(s)
  Yotaro Ochi, Kenichi Yoshida, Yasuhito Nannya, Ko Sasaki, Kinuko Mitani, Noriko Hosoya, Takayuki Ishikawa, Kazuma Ohyashiki, Naoto Takahashi, Hideki Makishima, Yuichi Shiraishi, Masashi Sanada, Akifumi Takaori-Kondo, Satoru Miyano, and Seishi Ogawa
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The molecular pathogenesis of DDX41-mutated myeloid neoplasms2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  The 83th Annual Meeting of the Japanese_Society of_Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Functional roles of DDX41 mutations in the development of myeloid malignancies2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  63rd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The molecular pathogenesis of DDX41-mutated myeloid neoplasms2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08394
[Presentation] The molecular pathogenesis of DDX41-mutated myeloid neoplasms2021
- Author(s)
  Ayana Kon, Masahiro M Nakagawa, Keisuke Kataoka, Ryosaku Inagaki, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The functional characterization of compound DDX41 germline and somatic R525H mutations in the development of myeloid malignancies2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The functional role of compound DDX41 germline and somatic R525H mutations in the development of myeloid neoplasms2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21546
[Presentation] Functional characterization of compound DDX41 germline and somatic R525H mutations in the development of myeloid malignancies2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by high throughput single cell RNA sequencing integrated with highly sensitive genotyping method2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  25th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of Clonal Evolution of AML Using Simultaneous Single-cell DNA/RNA Analysis2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Lanying Zhao, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  the 62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single-cell RNA/DNA sequencing2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第82回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The functional role of compound DDX41 germline and somatic R525H mutations in the development of myeloid neoplasms2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Functional characterization of compound DDX41 germline and somatic R525H mutations in the development of myeloid malignancies2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21546
[Presentation] The functional characterization of compound DDX41 germline and somatic R525H mutations in the development of myeloid malignancies2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] COMBINED COHESIN-RUNX1 DEFICIENCY SYNERGISTICALLY PERTURBS CHROMATIN LOOPING2020
- Author(s)
  Yotaro Ochi, Ayana Kon, Seishi Ogawa et al.
- Organizer
  25th Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21546
[Presentation] Genetic profiling and prognosis of blast crisis in chronic myeloid leukemia2020
- Author(s)
  Yotaro Ochi, Kenichi Yoshida, Ko Sasaki, Noriko Hosoya, Yusuke Shiozawa, Yasuhito Nannya, Takayuki Ishikawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Hideki Makishima, Akifumi Takaori-Kondo, Satoru Miyano, Kinuko Mitani, and Seishi Ogawa
- Organizer
  the 62nd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] 骨髄系腫瘍のクローン進化2020
- Author(s)
  Ayana Kon
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21546
[Presentation] Functional characterization of compound DDX41 germline and somatic R525H mutations in the development of myeloid malignancies2020
- Author(s)
  Kon A, Nakagawa MM, Inagaki R, Kataoka K, Ochi Y, Makishima H, Nakayama M, Koseki H, Nannya Y, Ogawa S
- Organizer
  62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct pathogenesis of clonal hematopoiesis revealed by single cell RNA sequencing integrated with highly sensitive genotyping method2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  62nd ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Early Clonal evolution of myeloid malignancies.2020
- Author(s)
  Masahiro M Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Zhao Lanying, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda and Seishi Ogawa
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of MDS and AML by single-cell DNA/RNA sequencing2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Zhao Lanying, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes.2020
- Author(s)
  Rurika Okuda, Yasuhito Nannya, Yotaro Ochi, Kazuhisa Chonabayashi, Maria Creignou, Hideki Makishima, June Takeda, Ayana Kon, Satoru Miyano, Hiroshi Handa, Shigeru Chiba, Kazuma Ohyashiki, Torsten Haferlach, Eva Hellstrom-Lindberg, Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of MDS and AML by single-cell DNA/RNA2020
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, June Takeda, Akinori Yoda, Ayana Kon, Hideki Makishima, Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of AML by a new single-cell sequencing platform2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Lanying Zhao, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  62nd American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Analysis of mechanisms underlying clonal evolution of AML by a new single-cell sequencing platform2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, Zhao Lanying, June Takeda, Akinori Yoda, Ayana Kon, Hisashi Tsurumi, Hideki Makishima, Seishi Ogawa
- Organizer
  The 81st JCA conference 2019, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] The role of compound DDX41 germline and somatic mutations in myeloid neoplasms2019
- Author(s)
  Ayana Kon, Masahiro Marshall Nakagawa, Yasuhito Nannya, Keisuke Kataoka, Yotaro Ochi, June Takeda, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Analysis of mechanisms underlying clonal evolution in MDS to sAML transformation by single-cell sequencing2019
- Author(s)
  Ryosaku Inagaki, Masahiro M Nakagawa, Yasuhito Nannya, Xingxing Qi, June Takeda, Akinori Yoda, Ayana Kon, Hideki Makishima, Seishi Ogawa
- Organizer
  The 78th JCA conference
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] Biological characterization of the U2af1 S34F mutation in the pathogenesis of myelodysplasia2019
- Author(s)
  Ayana Kon Yasuhito Nannya, Keisuke Kataoka, Manabu Nakayama, Haruhiko Koseki, Masashi Sanada, Hideki Makishima, Marshall Masahiro Nakagawa, Seishi Ogawa
- Organizer
  24th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656
[Presentation] STAG2 mutations alter epigenic and transcriptional dynamics in myeloid neoplasms.2019
- Author(s)
  Ayana Kon
- Organizer
  Meeting of Leukemic and Hematopoietic Stem Cells in Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Biological characterization of the U2af1 S34F mutation in the pathogenesis of myelodysplasia2019
- Author(s)
  Ayana Kon, Yasuhito Nannya, Keisuke Kataoka, Manabu Nakayama, Haruhiko Koseki, Masashi Sanada, Hideki Makishima, Marshall Masahiro Nakagawa, Seishi Ogawa
- Organizer
  24th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Functional analysis of DDX41 germline and somatic mutations in myeloid neoplasms.2018
- Author(s)
  Ayana Kon, June Takeda, Keisuke Kataoka, Kenichi Yoshida, Masahiro Marshall Nakagawa, Tetsuichi Yoshizato, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] スプライシング因子変異による骨髄異形成症候群発症の分子病態の解明2018
- Author(s)
  Ayana Kon
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Functional analysis of DDX41 germline and somatic mutations in myeloid neoplasms.2018
- Author(s)
  Ayana Kon, June Takeda, Keisuke Kataoka, Kenichi Yoshida, Masahiro Marshall Nakagawa, Tetsuichi Yoshizato, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Biological characterization of the U2af1 S34F mutation in the pathogenesis of myelodysplasia2018
- Author(s)
  Ayana Kon, Yasuhito Nannya, Marshall Masahiro Nakagawa, Keisuke Kataoka, Masashi Sanada, Manabu Nakayama, Haruhiko Koseki, Seishi Ogawa
- Organizer
  60th ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16084
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, Hideki Makishima, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Seishi Ogawa
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] The biological characterization of Srsf2 P95H mutation in the pathogenesis of myelodysplasia2016
- Author(s)
  Ayana Kon, Satoshi Yamazaki, Yusuke Shiozawa, Keisuke Kataoka, Yasunori Ota, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Kenichi Yoshida, Hideki Makisima, Yasuhito Nanya, Shinichi Kotani, June Takeda, Yosaku Watatani, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa
- Organizer
  The 78th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Yokohama, Kanagawa, Japan
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Biological roles and potential therapeutic targeting of spliceosome mutations in myelodysplasia2016
- Author(s)
  Ayana Kon, Seishi Ogawa
- Organizer
  The 75st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Kanagawa, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-16K19574

1. OGAWA Seishi (60292900)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
2. KOSEKI Haruhiko (40225446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. NAKAYAMA Manabu (30370927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. Itoh Takehiko (90501106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 吉田健一 (50738226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中川正宏 (10431850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
7. 片岡竜貴 (20343254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. 牧島秀樹 (40402127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 32 results
9. 南谷泰仁 (60451811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 36 results
10. 依田成玄 (70335454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
11. 江藤正俊 (90315078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SANADA Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. Kataoka Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. SHIRAISHI Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岩井一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 高折晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 進藤岳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 竹内理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 植畑拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 増田喬子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 牟安峰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 高田穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 片岡直行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 佐藤悠佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 広瀬哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 宮野悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KON AYANA 昆 彩奈

Kon Ayana 昆 彩奈

Research Projects

Research Products

Co-Researchers

胚細胞変異と後天的ゲノム異常の協調による先天性骨髄系腫瘍の分子病態の解明Principal Investigator

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Elucidating the mechanisms of clonal evolution of myeloid neoplasms with germline predispositionPrincipal Investigator

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Elucidating the contribution of the order of mutation acquisition to the clonal evolution of cancer using single-cell sequencing

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comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.

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Elucidating the molecular mechanisms underlying the clonal evolution of leukemic stem cellsPrincipal Investigator

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Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasmsPrincipal Investigator

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Computational reconstruction of the higher-order structure of chromosomes and linkage analysis between chromosome structure and phenotype

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[Journal Article] Germ line <i>DDX41</i> mutations define a unique subtype of myeloid neoplasms2023

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[Journal Article] SETBP1 is dispensable for normal and malignant hematopoiesis2023

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[Journal Article] Identification of an asymptomatic Shwachman-Bodian-Diamond syndrome mutation in a patient with acute myeloid leukemia.2022

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[Journal Article] A case of vasoactive intestinal peptide-secreting tumor (VIPoma) arising from MEN1 inactivation which recurred 15 years after the initial resection.2022

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[Journal Article] Successful azacitidine therapy for myelodysplastic syndrome associated with VEXAS syndrome.2022

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[Journal Article] Amplified <i>EPOR</i>/<i>JAK2</i> Genes Define a Unique Subtype of Acute Erythroid Leukemia2022

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[Journal Article] Tracing the evolutionary history of blood cells to the unicellular ancestor of animals.2022

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[Journal Article] Identification of an asymptomatic Shwachman Bodian Diamond syndrome mutation in a patient with acute myeloid leukemia2021

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KON AYANA 昆彩奈

Kon Ayana 昆彩奈