Murao Naoya 村尾直哉

… Alternative Names

村尾直哉ムラオナオヤ

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Researcher Number	20773534
Other IDs
Affiliation (Current)	2025: 宮崎大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2025: 宮崎大学, 医学部, 助教 2022 – 2023: 宮崎大学, 医学部, 助教 2017 – 2020: 宮崎大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Basic Section 44020:Developmental biology-related / Pathological medical chemistry Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 小胞体 / ニューロン新生 / Derlin-1 / 神経幹細胞 / 小胞体ストレス / 神経科学 / 成体ニューロン新生 / 脳内炎症 / グリア細胞 / 精神疾患 … More Except Principal Investigator … More 脳萎縮 / 小胞体ストレス / コレステロール / 能萎縮 / 神経変性疾患 Less

精子幹細胞の恒常性維持に関わる小胞体プロテオスタシスの役割の解明Principal Investigator
- Principal Investigator
  
  村尾直哉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  University of Miyazaki
神経幹細胞の休眠状態の獲得を制御する小胞体品質管理機構の役割Principal Investigator
- Principal Investigator
  
  村尾直哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  University of Miyazaki
病態脳における小胞体プロテオスタシス破綻によるコレステロール合成不全と脳萎縮
- Principal Investigator
  
  西頭英起
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  University of Miyazaki
The Role of endoplasmic reticulum homeostasis in senescence of neural stem cells during aging.Principal Investigator
- Principal Investigator
  
  Murao Naoya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  University of Miyazaki
Elucidation of general molecular mechanism of psychiatric disorder explored from chronic inflammation in the brain via endoplasmic reticulum stressPrincipal Investigator
- Principal Investigator
  
  Murao Naoya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki

All 2024 2023 2022 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis.2022
- Author(s)
  Sugiyama T, Murao N, Kadowaki H, Nishitoh H.
- Journal Title
  
  Scientific reports
  
  Volume: 12 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-022-26370-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06175, KAKENHI-PROJECT-22K06254, KAKENHI-PROJECT-23K24215
[Journal Article] Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain2018
- Author(s)
  Murao Naoya、Matsubara Shuzo、Matsuda Taito、Noguchi Hirofumi、Mutoh Tetsuji、Mutoh Masahiro、Koseki Haruhiko、Namihira Masakazu、Nakashima Kinichi
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 31-43
- DOI
  10.1016/j.neures.2018.05.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14820, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17K15624
[Journal Article] Role of the unfolded protein response in the development of central nervous system2017
- Author(s)
  Murao Naoya、Nishitoh Hideki
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 162 Issue: 3 Pages: 155-162
- DOI
  10.1093/jb/mvx047
- NAID
  40021326021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15624, KAKENHI-PUBLICLY-17H05670, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-15H05019
[Presentation] 小胞体膜タンパク質 Derlin-1 は成体ニューロン新生の維持を介しててんかん発作感受性と認知機能を制御する2024
- Author(s)
  村尾直哉
- Organizer
  第17回神経発生討論会・第20回成体脳のニューロン新生懇談会合同大会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus（小胞体タンパク質Derlin-1は成体海馬の神経幹細胞の恒常性を維持する）2023
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第64回日本神経化学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] 小胞体膜タンパク質Derlin-1は成体神経新生の維持を介しててんかん発作感受性と認知機能を制御する2023
- Author(s)
  村尾直哉、西頭英起
- Organizer
  令和5年度日本生化学会　九州支部例会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] 小胞体膜分子 Derlin-1 による成体神経新生制御を介した脳機能維持機構2023
- Author(s)
  村尾直哉
- Organizer
  第16回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] 小胞体品質は成体神経幹細胞の恒常性維持に重要である ER quality is important for the homeostasis of adult hippocampal neural stem cells2022
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24215
[Presentation] 中枢神経特異的Derlin-1欠損マウスの神経障害に対するケミカルシャペロンの作用メカニズム2022
- Author(s)
  杉山崇史、村尾直哉、西頭英起
- Organizer
  第15回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-23K24215
[Presentation] 小胞体品質は成体神経幹細胞の恒常性維持に重要である2022
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus2022
- Author(s)
  Naoya Murao, Hideki Nishitoh
- Organizer
  NEURO2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24215
[Presentation] 記憶・学習などの高次脳機能を支える小胞体品質管理機構2022
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第15回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-23K24215
[Presentation] 小胞体膜分子 Derlin-1の成体海馬ニューロン新生における役割2022
- Author(s)
  村尾直哉
- Organizer
  第15回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] 記憶・学習などの高次脳機能を支える小胞体品質管理機構2022
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第15回日本臨床ストレス応答学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus2022
- Author(s)
  Naoya Murao, Hideki Nishitoh
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-22K06254
[Presentation] The Endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus2020
- Author(s)
  Naoya Murao, Hideki Nishitoh
- Organizer
  第16回成体脳のニューロン新生懇談会
- Data Source
  KAKENHI-PROJECT-19K16016
[Presentation] Role of Derlin-1 in the Maintenance of Stem Cell Populations in Adult Hippocampal Neurogenesis2020
- Author(s)
  村尾直哉
- Organizer
  オルガネラゾーン若手の会
- Data Source
  KAKENHI-PROJECT-19K16016
[Presentation] 小胞体膜分子Derlin-1の成体海馬ニューロン新生における役割2019
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第14回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-19K16016
[Presentation] Role of Derlin-1 in the adult hippocampal neurogenesis2019
- Author(s)
  Naoya Murao, Hideki Nishitoh
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-19K16016
[Presentation] 小胞体膜分子 Derlin-1の成体海馬ニューロン新生における役割2019
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16016
[Presentation] 中枢神経組織における小胞体品質機構の破綻に起因する運動障害2018
- Author(s)
  杉山崇史、村尾直哉、西頭英起
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15624
[Presentation] 小胞体膜分子Derlinファミリーの成体海馬ニューロン新生における役割の解明2018
- Author(s)
  村尾直哉、西頭英起
- Organizer
  第13回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-17K15624
[Presentation] 中枢神経組織における小胞体品質機構の破綻に起因する運動障害2018
- Author(s)
  杉山崇史、村尾直哉、西頭英起
- Organizer
  第13回臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-17K15624
[Presentation] 中枢神経組織における小胞体品質機構の破綻に起因する運動障害メカニズム2018
- Author(s)
  杉山崇史、村尾直哉、西頭英起
- Organizer
  第13回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-17K15624
[Presentation] Role of endoplasmic reticulum (ER) quality control in learning and memory via adult hippocampal neurogenesis2018
- Author(s)
  Naoya Murao, Hideki Nishitoh
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15624

1. 西頭英起 (00332627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 上地珠代 (10381104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 門脇寿枝 (40568200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 松田泰斗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murao Naoya 村尾 直哉

村尾 直哉 ムラオ ナオヤ

Research Projects

Research Products

Co-Researchers

精子幹細胞の恒常性維持に関わる小胞体プロテオスタシスの役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

神経幹細胞の休眠状態の獲得を制御する小胞体品質管理機構の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

病態脳における小胞体プロテオスタシス破綻によるコレステロール合成不全と脳萎縮

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Role of endoplasmic reticulum homeostasis in senescence of neural stem cells during aging.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of general molecular mechanism of psychiatric disorder explored from chronic inflammation in the brain via endoplasmic reticulum stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the unfolded protein response in the development of central nervous system2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 小胞体膜タンパク質 Derlin-1 は成体ニューロン新生の維持を介しててんかん発作感受性と認知機能を制御する2024

Author(s)

Organizer

Data Source

[Presentation] An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus（小胞体タンパク質Derlin-1は成体海馬の神経幹細胞の恒常性を維持する）2023

Author(s)

Organizer

Data Source

[Presentation] 小胞体膜タンパク質Derlin-1は成体神経新生の維持を介しててんかん発作感受性と認知機能を制御する2023

Author(s)

Organizer

Data Source

[Presentation] 小胞体膜分子 Derlin-1 による成体神経新生制御を介した脳機能維持機構2023

Author(s)

Organizer

Data Source

[Presentation] 小胞体品質は成体神経幹細胞の恒常性維持に重要である ER quality is important for the homeostasis of adult hippocampal neural stem cells2022

Author(s)

Organizer

Data Source

[Presentation] 中枢神経特異的Derlin-1欠損マウスの神経障害に対するケミカルシャペロンの作用メカニズム2022

Author(s)

Organizer

Data Source

[Presentation] 小胞体品質は成体神経幹細胞の恒常性維持に重要である2022

Author(s)

Organizer

Data Source

[Presentation] An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus2022

Murao Naoya 村尾直哉

村尾直哉ムラオナオヤ