HAYASHI Akiyo 林晃世

… Alternative Names

林晃世ハヤシアキヨ

Less

Researcher Number	20779350
Other IDs
Affiliation (Current)	2025: 兵庫県立大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2017: 兵庫県立大学, 大学院生命理学研究科, 助教
Review Section/Research Field	Except Principal Investigator Functional biochemistry / Cell biology
Keywords	Except Principal Investigator DNA / タンパク質 / タンパク質分解 / 細胞周期 / 核酸 / DNA損傷 / 分解 / 修復 / 複製 / ゲノムDNA / スピンドル / DNA複製 / 紡錘体

Coupling of spindle checkpoint with initiation of DNA replication
- Principal Investigator
  
  Nishitani Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  University of Hyogo
Regulation of DNA replication through proteolysis coupled with PCNA cycle
- Principal Investigator
  
  Nishitani Hideo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Hyogo

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase.2018
- Author(s)
  Nukina K, Hayashi A, Shiomi Y, Sugasawa K, Ohtsubo M, Nishitani H.
- Journal Title
  
  Genes Cells.
  
  Volume: 23 Issue: 3 Pages: 200-213
- DOI
  10.1111/gtc.12563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07257, KAKENHI-PROJECT-26291025, KAKENHI-PUBLICLY-16H01311, KAKENHI-PROJECT-16H06307
[Journal Article] Mismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase.2017
- Author(s)
  Tanaka M, Takahara M, Nukina K, Hayashi A, Sakai W, Sugasawa K, Shiomi Y, Nishitani H.
- Journal Title
  
  Cell Cycle
  
  Volume: 16 Issue: 7 Pages: 673-684
- DOI
  10.1080/15384101.2017.1295179
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291025, KAKENHI-PROJECT-16K07257
[Journal Article] PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells.2014
- Author(s)
  Hayashi A, Suenaga N, Shiomi Y, Nishitani H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1170 Pages: 367-82
- DOI
  10.1007/978-1-4939-0888-2_19
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J07320, KAKENHI-PROJECT-26291025
[Presentation] DNA複製ライセンス化因子 Cdt1の M期における機能の解析2017
- Author(s)
  羽多野達也、前田武志、村上裕輔、林晃世、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2はPCNAと直接結合して機能する2017
- Author(s)
  林晃世、石井健士、末永尚弘、高原教代、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] Cdt2-PCNA融合体は CRL4Cdt2の抑制制御を損なう2017
- Author(s)
  荻野寛行、植田麻紗子、林晃世、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] 紫外線照射による G1期 CRL4Cdt2の活性化におけるミスマッチ修復系の関与2017
- Author(s)
  高原教代、田中美如、貫名康平、林晃世、酒井恒、菅澤薫、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] Direct binding between PCNA and E3 ligase CRL4Cdt2 supports substrate targeting, and subsequent proteolysis during DNA replication.2016
- Author(s)
  Akiyo Hayashi, Naohiro Suenaga, Michiyo Takahara, Takashi Ishii, Yasushi Shiomi, Hideo Nishitani
- Organizer
  10th 3R International Synposium
- Place of Presentation
  Matsue, Japan
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のピPボックスの役割＿細胞での解析2016
- Author(s)
  高原教代、末永尚弘、石井健士、林晃世、塩見泰史、西谷秀男
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のPIPボックスの役割＿試験管内解析2016
- Author(s)
  林晃世、高原教代、末永尚弘、石井健士、高橋達郎、塩見泰史、西谷秀男
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] In vitro analysis of DNA-bound PCNA dependent ubiquitin ligase CRL4-Cdt22015
- Author(s)
  Akiyo Hayashi, Yasushi Shiomi, Tatsuro S. Takahashi, Hideo Nishitani
- Organizer
  Cold Spring Harbor Laboratory Meeting “Eukaryotic DNA replication and genome maintenance”
- Place of Presentation
  Cold Spring Harbor Laboratory (New York, USA)
- Year and Date
  2015-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] S期クロマチン特異的なタンパク質分解系CRL4-Cdt2の制御機構
- Author(s)
  林晃世、塩見泰史高橋達郎末永尚弘西谷秀男
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase
- Author(s)
  Naohiro Suenaga, Takashi Ishii, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani
- Organizer
  2nd International Picobiology Institute Symposium “Development and Destruction”
- Place of Presentation
  Center for Advanced Science & Technology (Hyogo) Japan
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26650064
[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase
- Author(s)
  Naohiro Suenaga, Takashi Ishii, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani
- Organizer
  2nd International Picobiology Institute Symposium “Development and Destruction
- Place of Presentation
  Center for Advanced Science & Technology (Hyogo) Japan
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26291025

1. Nishitani Hideo (40253455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. SHIOMI Yasushi (80380567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results

HAYASHI Akiyo 林 晃世

林 晃世 ハヤシ アキヨ

Research Projects

Research Products

Co-Researchers

Coupling of spindle checkpoint with initiation of DNA replication

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of DNA replication through proteolysis coupled with PCNA cycle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells.2014

Author(s)

Journal Title

DOI

ISBN

Data Source

[Presentation] DNA複製ライセンス化因子 Cdt1の M期における機能の解析2017

Author(s)

Organizer

Data Source

[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2はPCNAと直接結合して機能する2017

Author(s)

Organizer

Data Source

[Presentation] Cdt2-PCNA融合体は CRL4Cdt2の抑制制御を損なう2017

Author(s)

Organizer

Data Source

[Presentation] 紫外線照射による G1期 CRL4Cdt2の活性化におけるミスマッチ修復系の関与2017

Author(s)

Organizer

Data Source

[Presentation] Direct binding between PCNA and E3 ligase CRL4Cdt2 supports substrate targeting, and subsequent proteolysis during DNA replication.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のピPボックスの役割＿細胞での解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のPIPボックスの役割＿試験管内解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] In vitro analysis of DNA-bound PCNA dependent ubiquitin ligase CRL4-Cdt22015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] S期クロマチン特異的なタンパク質分解系CRL4-Cdt2の制御機構

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase

HAYASHI Akiyo 林晃世

林晃世ハヤシアキヨ