Iriki Toyohisa 入來豊久

Researcher Number	20802078
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 熊本大学, 大学院生命科学研究部(医), 特定研究員 2019 – 2020: 熊本大学, 病院, 非常勤診療医師
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 腫瘍関連マクロファージ / 小細胞肺癌 / 天然物由来化合物 / DLL3 / STAT3 / スルフィド化合物 / 環状スルフィド化合物 / マクロファージ

腫瘍関連マクロファージをターゲットとした小細胞肺癌の新規治療戦略Principal Investigator
- Principal Investigator
  
  入來豊久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kumamoto University
Development of therapies for small cell lung cancer based on regulating macrophage activationPrincipal Investigator
- Principal Investigator
  
  Iriki Toyohisa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell?cell interaction with tumor-associated macrophage2023
- Author(s)
  Mito Remi、Iriki Toyohisa、Fujiwara Yukio、Pan Cheng、Ikeda Tsuyoshi、Nohara Toshihiro、Suzuki Makoto、Sakagami Takuro、Komohara Yoshihiro
- Journal Title
  
  Human Cell
  
  Volume: 36 Issue: 3 Pages: 1068-1080
- DOI
  10.1007/s13577-023-00895-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08257, KAKENHI-PROJECT-23K06362, KAKENHI-PROJECT-20K07122
[Journal Article] Cyclic sulfur compounds targeting macrophage polarization into M2/protumor phenotype and their anti-tumor effects2021
- Author(s)
  Pan Cheng、Fujiwara Yukio、Horlad Hasita、Iriki Toyohisa、Shiraishi Daisuke、Komohara Yoshihiro
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 6 Pages: 1331-1343
- DOI
  10.1007/s00262-021-03085-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08603, KAKENHI-PROJECT-19K09555, KAKENHI-PROJECT-22K09308
[Journal Article] Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment2020
- Author(s)
  Pan Cheng、Fujiwara Yukio、Horlad Hasita、Shiraishi Daisuke、Iriki Toyohisa、Tsuboki Jyunko、Ikeda Tsuyoshi、Komohara Yoshihiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 00262-00262
- DOI
  10.3389/fphar.2020.00262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08603, KAKENHI-PROJECT-19K09555, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17K08763, KAKENHI-PROJECT-20K07122
[Presentation] Onionin A and Ursolic acid inhibit small cell lung cancer proliferation by regulating macrophage activation2022
- Author(s)
  Yukio Fujiwara, Remi Mito, Toyohisa Iriki, Cheng Pan, Takuro Sakagami, Yoshihiro Komohara
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08257

1. 藤原章雄 (70452886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 一安秀範 (50419636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 坂上拓郎 (00444159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 菰原義弘 (40449921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Iriki Toyohisa 入來豊久

Research Projects

Research Products

Co-Researchers

腫瘍関連マクロファージをターゲットとした小細胞肺癌の新規治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapies for small cell lung cancer based on regulating macrophage activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell?cell interaction with tumor-associated macrophage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclic sulfur compounds targeting macrophage polarization into M2/protumor phenotype and their anti-tumor effects2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Onionin A and Ursolic acid inhibit small cell lung cancer proliferation by regulating macrophage activation2022

Author(s)

Organizer

Data Source

Iriki Toyohisa 入來 豊久

Research Projects

Research Products

Co-Researchers

腫瘍関連マクロファージをターゲットとした小細胞肺癌の新規治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapies for small cell lung cancer based on regulating macrophage activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell?cell interaction with tumor-associated macrophage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclic sulfur compounds targeting macrophage polarization into M2/protumor phenotype and their anti-tumor effects2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Onionin A and Ursolic acid inhibit small cell lung cancer proliferation by regulating macrophage activation2022

Author(s)

Organizer

Data Source

Iriki Toyohisa 入來豊久