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Hayashi Hiroki  林 宏樹

ORCIDConnect your ORCID iD *help
Researcher Number 20813364
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 寄附講座准教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 大阪大学, 大学院医学系研究科, 寄附講座准教授
2022: 大阪大学, 大学院医学系研究科, 寄附講座講師
2020 – 2021: 大阪大学, 医学系研究科, 寄附講座講師
2019 – 2020: 大阪大学, 医学系研究科, 寄附講座助教
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 52010:General internal medicine-related
Except Principal Investigator
Basic Section 52010:General internal medicine-related / Basic Section 56010:Neurosurgery-related / Basic Section 56060:Ophthalmology-related / Basic Section 53020:Cardiology-related / Basic Section 53040:Nephrology-related
Keywords
Principal Investigator
翻訳後修飾 / 動脈硬化 / 糖代謝 / 老化 / ワクチン / エンドセリン受容体 / エンドセリン / GPCR / 一酸化窒素 / 慢性炎症 … More / βアレスチン / G蛋白共役型受容体 / 単球 / ケモカイン … More
Except Principal Investigator
ワクチン / 炎症 / 脳梗塞 / 治療ワクチン / 神経再生 / Toll-like receptor / FAP / ミクログリア / オートタキシン / プロレニン / ペプチドワクチン / 糖尿病網膜症 / 心線維化 / 心不全 / トリプトファン / SARS-CoV2 / アンジオテンシン変換酵素2(ACE2) / COVID-19 / 老化 / ACE2 / アンジオテンシン変換酵素2 / 老化細胞 / 血栓回収療法 / 脳血管障害 / 部分再開通 / RANKLペプチド / LGR / LGR4 / 血液脳関門 / 神経細胞死 / 糖尿病 / 慢性炎症 / 糖尿病性腎症 / 糖尿病腎症 Less
  • Research Projects

    (10 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (12 People)
  •  高齢者糖尿病に対する新規ワクチン療法の開発Principal Investigator

    • Principal Investigator
      林 宏樹
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      The University of Osaka
  •  Development of a Novel Treatment for Diabetic Retinopathy Using Peptide Vaccine Technology

    • Principal Investigator
      横田 陽匡
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Asahikawa Medical College
  •  脳梗塞後炎症免疫機構および神経再生におけるFAPの機能解明と治療応用への検討

    • Principal Investigator
      島村 宗尚
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Osaka University
  •  Development of a novel therapy for cardiac fibrosis using a cell removal vaccine

    • Principal Investigator
      勝谷 友宏
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  高齢者のCOVID-19感染リスクを安全に低下し得る新規戦略の開発

    • Principal Investigator
      竹下 ひかり
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  NO-mediated endothelin receptor function in the development of atheroscrelosisPrincipal Investigator

    • Principal Investigator
      Hayashi Hiroki
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  Therapeutic vaccine for senolysis

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Development of a novel therapeutic vaccine for diabetic nephropathy

    • Principal Investigator
      Katsuya Tomohiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  Pathophysiological analysis and development of therapy in partial reperfusion in ischemic stroke

    • Principal Investigator
      Shimamura Munehisa
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Osaka University
  •  Regulation of chemokine signaling by post-translational modification of beta-arrestin and relationship with atherosclerosisPrincipal Investigator

    • Principal Investigator
      Hayashi Hiroki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University

All 2025 2023 2020 2019

All Journal Article Presentation

  • [Journal Article] A Vaccine Against Fibroblast Activation Protein Improves Murine Cardiac Fibrosis by Preventing the Accumulation of Myofibroblasts.2025

    • Author(s)
      Yoshida S, Hayashi H, Kawahara T, Katsuki S, Kimura M, Hino R, Sun J, Nakamaru R, Tenma A, Toyoura M, Baba S, Shimamura M, Katsuya T, Morishita R, Rakugi H, Matoba T,  Nakagami H.
    • Journal Title

      Circ Res.

      Volume: 136 Issue: 1 Pages: 26-40

    • DOI

      10.1161/circresaha.124.325017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24229, KAKENHI-PROJECT-23K07504, KAKENHI-PROJECT-22K16067
  • [Journal Article] Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine2023

    • Author(s)
      Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Miyata Keishi、Torigoe Daisuke、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
    • Journal Title

      npj Vaccines

      Volume: 8 Issue: 1 Pages: 168-168

    • DOI

      10.1038/s41541-023-00770-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21H02827
  • [Presentation] 脳梗塞におけるFibroblast activation proteinの発現及び機能解析2025

    • Author(s)
      島村宗尚、鞠楠、張今陽、林宏樹、 森下竜一、望月秀樹
    • Organizer
      第50回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-24K12220
  • [Presentation] Regulation of CX3CR1 Signaling and Function by NO-Mediated Post-Translational Modification2020

    • Author(s)
      Hiroki Hayashi
    • Organizer
      The 21st International Vascular Biology Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08515
  • [Presentation] Inflammation-associated NO regulates chemokine signaling via CX3CR12019

    • Author(s)
      Hiroki Hayashi, Hironori Nakagami
    • Organizer
      The 3rd Asia Australia Vascular Biology Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08515
  • 1.  Nakagami Hironori (20325369)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 2 results
  • 2.  Shimamura Munehisa (60422317)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  Katsuya Tomohiro (30311757)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  竹下 ひかり (10791577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  山本 浩一 (00528424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  樂木 宏実 (20252679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高橋 利匡 (60807270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  横田 陽匡 (60431417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  山上 聡 (10220245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  張 今陽 (90869124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  向山 政志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  森下 竜一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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