Tanaka Tomoko 田中智子

Researcher Number	20822414
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 客員講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 客員講師
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator Hippo経路 / MAPK経路 / YAP阻害剤 / MEK阻害剤 / 神経芽腫

Pre-clinical research for mechanism of resistance toward MEK inhibitors in neuroblastomaPrincipal Investigator
- Principal Investigator
  
  Tanaka Tomoko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto Prefectural University of Medicine

All 2022 2021 2020

All Journal Article Presentation

[Journal Article] Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model2021
- Author(s)
  Togashi Yuichi、Tanaka Tomoko、Takemoto Masakazu、Takeuchi Yuki、Higashi Mayumi、Fumino Shigehisa、Tajiri Tatsuro
- Journal Title
  
  Journal of Pediatric Surgery
  
  Volume: 56 Issue: 7 Pages: 1233-1239
- DOI
  10.1016/j.jpedsurg.2021.03.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-20K08937, KAKENHI-PROJECT-20K08988
[Journal Article] The synergistic antitumor effect of combination therapy with a MEK inhibitor and YAP inhibitor on pERK-positive neuroblastoma2021
- Author(s)
  Takemoto Masakazu、Tanaka Tomoko、Tsuji Ryota、Togashi Yuichi、Higashi Mayumi、Fumino Shigehisa、Tajiri Tatsuro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 570 Pages: 41-46
- DOI
  10.1016/j.bbrc.2021.07.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-20K08937, KAKENHI-PROJECT-20K08988
[Journal Article] Immunohistochemical staining of phosphorylated-ERK in post-chemotherapeutic samples is a potential predictor of the prognosis of neuroblastoma2021
- Author(s)
  Tanaka Tomoko、Togashi Yuichi、Takeuchi Yuki、Higashi Mayumi、Fumino Shigehisa、Tajiri Tatsuro
- Journal Title
  
  Pediatric Surgery International
  
  Volume: 37 Issue: 2 Pages: 287-291
- DOI
  10.1007/s00383-020-04806-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08987, KAKENHI-PROJECT-18K08547, KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-20K08937, KAKENHI-PROJECT-20K08988
[Journal Article] Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience2020
- Author(s)
  Tanaka Tomoko、Amano Hizuru、Tanaka Yujiro、Takahashi Yoshiyuki、Tajiri Tatsuro、Tainaka Takahisa、Shirota Chiyoe、Sumida Wataru、Yokota Kazuki、Makita Satoshi、Tani Yukiko、Hinoki Akinari、Uchida Hiroo
- Journal Title
  
  BMC Pediatrics
  
  Volume: 20 Issue: 1 Pages: 292-292
- DOI
  10.1186/s12887-020-02183-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08937, KAKENHI-PROJECT-20K08987, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-18K08547
[Presentation] pERK陽性神経芽腫に対するMEK阻害剤トラメチニブとYAP阻害剤CA3併用療法のin vitroおよびin vivoにおける抗腫瘍効果の検討．2022
- Author(s)
  竹本正和，田中智子，辻　亮多，富樫佑一，東　真弓，文野誠久，田尻達郎
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08937
[Presentation] MRDマウスモデルを用いたMEK阻害剤による神経芽腫局所微小残存病変に対する新たな治療戦略の検討．2021
- Author(s)
  富樫佑一，竹本正和，竹内雄毅，田中智子，東真弓，文野誠久，田尻達郎
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08937
[Presentation] The synergistic anti-tumor effect of combination therapy with a MEK inhibitor and YAP inhibitor on pERK-positive neuroblastoma2021
- Author(s)
  Takemoto M, Tanaka M, Tsuji R, Togashi Y, Higashi M, Fumino S, Tajiri T.
- Organizer
  54th Pacific Association of Pediatric Surgeons
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08937
[Presentation] 神経芽腫局所微小残存病変モデルマウスを用いたMEK阻害剤の再発抑制効果の検討．2020
- Author(s)
  富樫佑一，竹本正和，竹内雄毅，田中智子，東　真弓，文野誠久，田尻達郎
- Organizer
  第57回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08937
[Presentation] Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model.2020
- Author(s)
  Togashi Y, Takemoto M, Takeuchi Y, Tanaka T, Higashi M, Fumino S, Tajiri T
- Organizer
  53rd Pacific Association of Pediatric Surgeons (PAPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08937

1. 東真弓 (10380453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 文野誠久 (40405254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. 田尻達郎 (80304806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

Tanaka Tomoko 田中 智子

Research Projects

Research Products

Co-Researchers

Pre-clinical research for mechanism of resistance toward MEK inhibitors in neuroblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The synergistic antitumor effect of combination therapy with a MEK inhibitor and YAP inhibitor on pERK-positive neuroblastoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunohistochemical staining of phosphorylated-ERK in post-chemotherapeutic samples is a potential predictor of the prognosis of neuroblastoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] pERK陽性神経芽腫に対するMEK阻害剤トラメチニブとYAP阻害剤CA3併用療法のin vitroおよびin vivoにおける抗腫瘍効果の検討．2022

Author(s)

Organizer

Data Source

[Presentation] MRDマウスモデルを用いたMEK阻害剤による神経芽腫局所微小残存病変に対する新たな治療戦略の検討．2021

Author(s)

Organizer

Data Source

[Presentation] The synergistic anti-tumor effect of combination therapy with a MEK inhibitor and YAP inhibitor on pERK-positive neuroblastoma2021

Author(s)

Organizer

Data Source

[Presentation] 神経芽腫局所微小残存病変モデルマウスを用いたMEK阻害剤の再発抑制効果の検討．2020

Author(s)

Organizer

Data Source

[Presentation] Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model.2020

Author(s)

Organizer

Data Source

Tanaka Tomoko 田中智子