Okuno Noriko 奥野のり子

… Alternative Names

奥野のり子オクノノリコ

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Researcher Number	20836168
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 助教
Affiliation (based on the past Project Information) *help	2024: 富山大学, 学術研究部医学系, 助教 2019 – 2020: 富山大学, 学術研究部医学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology
Keywords	Principal Investigator PDGFR / 遺伝子改変マウス / 神経 / 膠芽腫 / 脳腫瘍 Except Principal Investigator TGF-βシグナル / VEGFシグナル / リンパ管 / EGFシグナル / 出芽 … More / リンパ管新生 / 希突起膠細胞 / 神経 / 神経賦活因子 / 神経変性 / 増殖因子 / 血小板 / 再生 / 筋萎縮性側索硬化症 / 線維芽細胞 / 血管透過性 / 稀突起膠細胞 / 血管周囲性線維芽細胞 / 希突起膠細胞前駆細胞 / 脳血液関門 / 神経保護作用 / 神経変性疾患 / 脳梗塞 / 受容体 / 血小板由来増殖因子 Less

血管構築の制御を介して高悪性度膠芽腫の予後を改善するPrincipal Investigator
- Principal Investigator
  
  奥野のり子
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
Elucidating the black box of lymphangiogenesis in the early embryogenesis period
- Principal Investigator
  
  山本誠士
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  University of Toyama
Neuropathology related to oligodendrocyte disorder
- Principal Investigator
  
  Sasahara Masakiyo
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Toyama

All 2023 2022 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] PDGF receptor signal mediates the contribution of Nestin-positive cell lineage to subcutaneous fat development2023
- Author(s)
  Takashima Yumi、Yamamoto Seiji、Okuno Noriko、Hamashima Takeru、Dang Son Tung、Tran Ngoc Dung、Okita Naruho、Miwa Fujikawa、Dang Thanh Chung、Matsuo Mina、Takao Keizo、Fujimori Toshihiko、Mori Hisashi、Tobe Kazuyuki、Noguchi Makoto、Sasahara Masakiyo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 658 Pages: 27-35
- DOI
  10.1016/j.bbrc.2023.03.052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17422, KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-21H02713, KAKENHI-PROJECT-23K24108
[Journal Article] Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice2020
- Author(s)
  Nguyen Quang Linh、Okuno Noriko、Hamashima Takeru、Dang Son Tung、Fujikawa Miwa、Ishii Yoko、Enomoto Atsushi、Maki Takakuni、Nguyen Hoang Ngoc、Nguyen Van Tuyen、Fujimori Toshihiko、Mori Hisashi、Andrae Johanna、Betsholtz Christer、Takao Keizo、Yamamoto Seiji、Sasahara Masakiyo
- Journal Title
  
  Angiogenesis
  
  Volume: 24 Issue: 1 Pages: 35-46
- DOI
  10.1007/s10456-020-09742-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K06888
[Journal Article] Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha2020
- Author(s)
  Hamashima Takeru、Ishii Yoko、Nguyen Linh Quang、Okuno Noriko、Sang Yang、Matsushima Takako、Kurashige Yoichi、Takebayashi Hirohide、Mori Hisashi、Fujimori Toshihiko、Yamamoto Seiji、Sasahara Masakiyo
- Journal Title
  
  Neuroscience
  
  Volume: 436 Pages: 11-26
- DOI
  10.1016/j.neuroscience.2020.04.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K06888, KAKENHI-PROJECT-18H02592
[Journal Article] Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain2019
- Author(s)
  Dang Thanh Chung、Ishii Yoko、Nguyen Van De、Yamamoto Seiji、Hamashima Takeru、Okuno Noriko、Nguyen Quang Linh、Sang Yang、Ohkawa Noriaki、Saitoh Yoshito、Shehata Mohammad、Takakura Nobuyuki、Fujimori Toshihiko、Inokuchi Kaoru、Mori Hisashi、Andrae Johanna、Betsholtz Christer、Sasahara Masakiyo
- Journal Title
  
  Cell Reports
  
  Volume: 27 Issue: 4 Pages: 1073-1089.e5
- DOI
  10.1016/j.celrep.2019.03.084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06888, KAKENHI-PUBLICLY-19H04899, KAKENHI-PROJECT-16H02470, KAKENHI-PROJECT-17H04062
[Journal Article] Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast2018
- Author(s)
  Yamada Kohta、Hamashima Takeru、Ishii Yoko、Yamamoto Seiji、Okuno Noriko、Yoshida Naofumi、Yamada Moe、Huang Ting Ting、Shioda Norifumi、Tomihara Kei、Fujimori Toshihiko、Mori Hisashi、Fukunaga Kohji、Noguchi Makoto、Sasahara Masakiyo
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 51 Issue: 3 Pages: 1461-1479
- DOI
  10.1159/000495594
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-16K08265
[Patent] 嚢胞性リンパ管腫治療薬2020
- Inventor(s)
  山本誠士，笹原正清，濱島丈，奥野のり子
- Industrial Property Rights Holder
  山本誠士，笹原正清，濱島丈，奥野のり子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-201580
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] 髄鞘低形成マウス脳病変における血管周囲性線維芽細胞の解析2023
- Author(s)
  奥野のり子, 濱島丈, 藤川美和, 笹原正清, 山本誠士
- Organizer
  CVMW2023
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] 髄膜固有線維芽細胞は、髄鞘低形成脳の炎症性組織改変を誘導する2022
- Author(s)
  奥野のり子, 山本誠士, 濱島丈, 藤川美和, 松島貴子, 山内直岳, 笹原正清
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] PDGFRαノックアウトマウスを用いた LLC 皮下移植モデルにおける腫瘍発育動態の解析2022
- Author(s)
  林政雄, 山本誠士, 吉田尚史, 高島侑美, Dang Son Tung, 奥野のり子, 濱島丈, 伊東史子, 笹原正清
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] マウス皮下血管新生モデルを用いた PDGFRβの血管新生における役割の検討2022
- Author(s)
  山本誠士, 奥野のり子, 濱島丈, 林政雄, 吉田尚史, 堀川慎二郎, 山内直岳, 笹原正清
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] PDGFRシグナルは血管正常化をベースとするglioma治療の有力なターゲットである2022
- Author(s)
  松田未央, 山本誠士, 奥野のり子, 濱島丈, 山内直岳, 笹原正清
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] The role of macrophages in the perivascular space2022
- Author(s)
  Yamamoto S, Azuma E, Okuno N, Hamashima T, Sasahara M
- Organizer
  IVBM2022, San Francisco Bay Area
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] An involvement of PDGFRα in the senescence of neural stem/progenitor cells2022
- Author(s)
  Dang Son Tung, 奥野のり子, 濱島丈, 山本誠士, 山内直岳, 藤川美和, 松島貴子, Nguyen Quang Linh, 笹原正清
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K24108
[Presentation] LLC 皮下移植モデルにおけるPDGFRαノックアウトマウスの腫瘍発育動態の解析.2020
- Author(s)
  林政雄，山本誠士，吉田尚史，高島侑美，Sang Y, Nguyen QL, Dang ST, 奥野のり子，濱島丈，笹原正清.
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] Distinctive role of PDGFRα-expressing two cell populations in ischemic stroke.2020
- Author(s)
  Nguyen QL, Yamamoto S, Okuno N, Hamashima T, Sang Y, Hayashi M, Dang ST, Takashima Y, Sasahara M.
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] PDGFRβ knockout fibroblasts are involved in the formation of cyst-like lymphatic vessels.2020
- Author(s)
  Yamamoto S, Yoshida N, Hamashima T, Okuno N, Horikawa S, Ishii Y, Sasahara M.
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] 線維芽細胞の遊走におけるPDGFR二量体シグナルの役割2019
- Author(s)
  山田萌, 山本誠士, 山田浩太, 濱島丈, 奥野のり子, 石井陽子, 笹原正清
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] The role of PDGFRα in the oligodendrogenesis and myelin formation in forebrain.2019
- Author(s)
  Hamashima T, Ishii Y, Yamamoto S, Ngyuen QL, Okuno N, Sang Y, Matsushima T, Kurashige Y, Sasahara M
- Organizer
  BRAIN & BRAIN PET 2019 (The 29th International Symposium on Cerebral Blood Flow, Metabolism and Function)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] PDGFRαは成体脳のSVZに存在する神経幹細胞の増殖や分化に重要である(PDGFRa controls the stem cell activities in the subventricular zone stem cells in adult mouse brain)2019
- Author(s)
  グエンクアン・リン, 山本誠士, 濱島丈, 奥野のり子, 桑洋, 笹原正清
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] 神経膠腫におけるPDGF阻害後に誘導される血管表現型(Vascular phenotypes induced after PDGF inhibition in glioma)2019
- Author(s)
  桑洋, 山本誠士, 濱島丈, 奥野のり子, 倉茂洋一, 松島貴子, Nguyen Quang Linh, 石井陽子, 笹原正清
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] 中枢神経系の微小血管を被覆するペリサイトのheterogeneity2019
- Author(s)
  山本誠士, 濱島丈, 奥野のり子, 石井陽子, 笹原正清
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] PDGFRα controls dynamic remodelling of oligodendrocyte progenitor cells in adult brain.2019
- Author(s)
  Ngyuen QL, Dang TC, Hamashima T, Sang Y, Okuno N, Ishii Y, Sasahara M, Yamamoto S
- Organizer
  BRAIN & BRAIN PET 2019 (The 29th International Symposium on Cerebral Blood Flow, Metabolism and Function)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] 組織の恒常性と破綻に関与するheterogeneousなペリサイト2019
- Author(s)
  山本誠士, 奥野のり子, 濱島丈, 笹原正清
- Organizer
  CVMW2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062
[Presentation] Diverse effects of PDGF signals in glioma growth.2019
- Author(s)
  Sang Y, Hamashima T, Yamamoto S, Okuno N, Ngyuen QL, Ishii Y, Sasahara M
- Organizer
  BRAIN & BRAIN PET 2019 (The 29th International Symposium on Cerebral Blood Flow, Metabolism and Function)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04062

1. Sasahara Masakiyo (20154015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
2. 山本誠士 (10456361)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
3. 森寿 (00239617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 石井陽子 (00361949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 濱島丈 (80467092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
6. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 福永浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okuno Noriko 奥野 のり子

奥野 のり子 オクノ ノリコ

Research Projects

Research Products

Co-Researchers

血管構築の制御を介して高悪性度膠芽腫の予後を改善するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the black box of lymphangiogenesis in the early embryogenesis period

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuropathology related to oligodendrocyte disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] PDGF receptor signal mediates the contribution of Nestin-positive cell lineage to subcutaneous fat development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast2018

Author(s)

Journal Title

DOI

Data Source

[Patent] 嚢胞性リンパ管腫治療薬2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 髄鞘低形成マウス脳病変における血管周囲性線維芽細胞の解析2023

Author(s)

Organizer

Data Source

[Presentation] 髄膜固有線維芽細胞は、髄鞘低形成脳の炎症性組織改変を誘導する2022

Author(s)

Organizer

Data Source

[Presentation] PDGFRαノックアウトマウスを用いた LLC 皮下移植モデルにおける腫瘍発育動態の解析2022

Author(s)

Organizer

Data Source

[Presentation] マウス皮下血管新生モデルを用いた PDGFRβの血管新生における役割の検討2022

Author(s)

Organizer

Data Source

[Presentation] PDGFRシグナルは血管正常化をベースとするglioma治療の有力なターゲットである2022

Author(s)

Organizer

Data Source

[Presentation] The role of macrophages in the perivascular space2022

Author(s)

Organizer

Data Source

[Presentation] An involvement of PDGFRα in the senescence of neural stem/progenitor cells2022

Okuno Noriko 奥野のり子

奥野のり子オクノノリコ