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Hatakeyama Masahiro  畠山 公大

ORCIDConnect your ORCID iD *help
Researcher Number 20843618
Other IDs
Affiliation (Current) 2025: 新潟大学, 脳研究所, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 新潟大学, 脳研究所, 助教
2020 – 2022: 新潟大学, 医歯学総合研究科, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related
Except Principal Investigator
Basic Section 56010:Neurosurgery-related
Keywords
Principal Investigator
脳卒中 / 機能的MRI / 失語症 / 再生医学 / 脳梗塞 / 低酸素低糖刺激 / 機能再生 / 低酸素領域 / 末梢血単核球 / 脳虚血 / 細胞療法 / 再生医療 … More
Except Principal Investigator
… More VEGF / ミクログリア / 機能回復 / miRNA / エクソソーム / 細胞療法 / 脳梗塞 / 末梢血単核球 Less
  • Research Projects

    (3 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (3 People)
  •  小脳は失語症に対し何をしているのか?-機能的MRIを用いた小脳性機能代償の証明Principal Investigator

    • Principal Investigator
      畠山 公大
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Niigata University
  •  Development of brain regeneration therapy mediated by peripheral blood mononuclear cell-derived exosomes through cell polarization

    • Principal Investigator
      金澤 雅人
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Niigata University
  •  underlying mechanisms of cell therapy using tissue protective-peripheral blood mononuclear cells against ischemic strokePrincipal Investigator

    • Principal Investigator
      Hatakeyama Masahiro
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Niigata University

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Next-generation regenerative therapy for ischemic stroke using peripheral blood mononuclear cells2024

    • Author(s)
      Kanazawa Masato、Ninomiya Itaru、Otsu Yutaka、Hatakeyama Masahiro
    • Journal Title

      Neural Regeneration Research

      Volume: 19 Issue: 11 Pages: 2341-2342

    • DOI

      10.4103/nrr.nrr-d-23-01784

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19441, KAKENHI-PROJECT-20K16485, KAKENHI-PROJECT-23K24442
  • [Journal Article] Oxygen?Glucose Deprived Peripheral Blood Mononuclear Cells Protect Against Ischemic Stroke2023

    • Author(s)
      Otsu Yutaka、Hatakeyama Masahiro、Kanayama Takeshi、Akiyama Natsuki、Ninomiya Itaru、Omae Kaoru、Kato Taisuke、Onodera Osamu、Fukushima Masanori、Shimohata Takayoshi、Kanazawa Masato
    • Journal Title

      Neurotherapeutics

      Volume: 20 Issue: 5 Pages: 1369-1387

    • DOI

      10.1007/s13311-023-01398-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19441, KAKENHI-PROJECT-20K16485, KAKENHI-PROJECT-23K24442
  • [Presentation] 低酸素低糖刺激末梢血単核球を用いた細胞療法は虚血再灌流後低酸素領域を治療ターゲットとする2024

    • Author(s)
      金山武史、畠山公大、大津裕、秋山夏葵、二宮格、小野寺理、下畑享良、金澤雅人
    • Organizer
      第49回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] miR-155-5pのダウンレギュレーションを介して末梢血単核球は組織保護的極性を獲得する2024

    • Author(s)
      大津裕,秋山夏葵,金山武史,二宮格,畠山公大,小野寺理,下畑享良,金澤雅人
    • Organizer
      第49回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] Oxygen-glucose deprived peripheral blood mononuclear cells alter microglial phenotype by secretome2024

    • Author(s)
      Masahiro Hatakeyama, Yutaka Otsu, Natsuki Akiyama, Takeshi Kanayama, Itaru Ninomiya, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      第65回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K16485
  • [Presentation] Peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation regulate microglial polarization by secretome after cerebral ischemia2024

    • Author(s)
      Masahiro Hatakeyama, Yutaka Otsu, Natsuki Akiyama, Takeshi Kanayama, Itaru Ninomiya, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      International Stroke Conference, 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] 末梢血単核球を用いた血管新生、神経分化による脳梗塞細胞療法2024

    • Author(s)
      金澤雅人、畠山公大、二宮格、大津裕、小野寺理
    • Organizer
      第49回日本脳卒中学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] Peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation regulate microglial polarization by secretome after cerebral ischemia2024

    • Author(s)
      Masahiro Hatakeyama, Yutaka Otsu, Natsuki Akiyama, Takeshi Kanayama, Itaru Ninomiya, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      International Stroke Conference 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16485
  • [Presentation] ミクログリアを介した虚血後リン酸化タウ蛋白の排泄分解機構の検討2024

    • Author(s)
      秋山夏葵、大津裕、金山武史、畠山公大、小野寺理、金澤雅人
    • Organizer
      第49回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] 抗好中球細胞質抗体が陰性で 初回治療の2年後に 好酸球性多発血管炎性肉芽腫症と診断した一例2023

    • Author(s)
      畠山 貴成、木下 悠紀子、二宮 格、柴崎 康彦、山崎 翔子、小林 大介、金澤 雅人、小野寺 理
    • Organizer
      日本内科学会ことはじめ2023
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] Tissue remodeling by peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation2023

    • Author(s)
      Takeshi Kanayama、Masahiro Hatakeyama、Yutaka Otsu、Natsuki Akiyama、Itaru Ninomiya、Osamu Onodera、Takayoshi Shimohata、Masato Kanazawa
    • Organizer
      第64回日本神経学会学術大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] miR-155-5pを介して末梢血単核球は組織保護的極性を獲得し脳梗塞に対する細胞療法となる2023

    • Author(s)
      大津裕,秋山夏葵,金山武史,二宮格,畠山公大,小野寺理,下畑享良,金澤雅人
    • Organizer
      第66回日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] miRNA-mediated polarization of oxygen-glucose deprivation-induced peripheral blood mononuclear cells2023

    • Author(s)
      Yutaka Otsu, Masahiro Hatakeyama, Takeshi Kanayama, Natsuki Akiyama, Itaru Ninomiya, Kaoru Omae, Osamu Onodera, Masanori Fukushima, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      第64回日本神経学会学術大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] 脳梗塞治療のための低酸素低糖刺激末梢血単核球療法の確立2023

    • Author(s)
      金澤雅人, 畠山公大, 大津裕, 小野寺理, 下畑享良
    • Organizer
      第66回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] Peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation cause microglial phenotype conversion by secretome after cerebral ischemia2023

    • Author(s)
      Masahiro Hatakeyama, Yutaka Otsu, Natsuki Akiyama, Takeshi Kanayama, Itaru Ninomiya, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      11th Japan-Korea Joint Stroke Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16485
  • [Presentation] OGD-PBMC細胞療法は、neurovascular unit介入により脳梗塞後に機能回復を促進させる2023

    • Author(s)
      金澤雅人, 畠山公大
    • Organizer
      第66回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] Peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation cause microglial phenotype conversion by secretome after cerebral ischemia2023

    • Author(s)
      Masahiro Hatakeyama, Yutaka Otsu, Natsuki Akiyama, Takeshi Kanayama, Itaru Ninomiya, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa
    • Organizer
      11th Japan-Korea Joint Stroke Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24442
  • [Presentation] 脳梗塞に対する低酸素低糖刺激末梢血単核球投与による脳内変化2022

    • Author(s)
      金山武史,畠山公大,大津裕,秋山 夏葵,二宮格,小野寺理,下畑享良 ,金澤雅人
    • Organizer
      第65回日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16485
  • 1.  金澤 雅人 (80645101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 2.  下畑 享良 (60361911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  田井中 一貴 (80506113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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