KOZONO TAKUMA 小薗拓馬

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KOZONO Takuma 小薗拓馬

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Researcher Number	20876180
Other IDs	https://orcid.org/0000-0003-0253-9416
Affiliation (Current)	2026: 東京農工大学, (連合)農学研究科(研究院), 助教 2026: 東京農工大学, 学内共同利用施設等, 特任助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京農工大学, 学内共同利用施設等, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49040:Parasitology-related / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator カルシウムシグナリング / ケモセンシング / 寄生虫感染応答 / タフト細胞 / 味覚 / 塩味感知 / 味蕾細胞 / イノシトール三リン酸受容体 / Jaw1

Molecular mechanism of the helminth expulsion by small intestinal epithelial tuft cellsPrincipal Investigator
- Principal Investigator
  
  KOZONO Takuma
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Tokyo University of Agriculture and Technology
The mechanism of salt taste perception by a novel subpopulation of taste bud cellsPrincipal Investigator
- Principal Investigator
  
  KOZONO Takuma
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture and Technology

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Jaw1 accelerates the reaction speed of the Ca2+ signals via ITPRs upon GPCR stimulation2025
- Author(s)
  Kozono Takuma、Matsui Hitomi、Bandalan Marielle Fernandez、Tonozuka Takashi、Nishikawa Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 15 Issue: 1 Pages: 10104-10104
- DOI
  10.1038/s41598-025-94489-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14511
[Journal Article] Structural basis for the recognition of α-1,6-branched α-glucan by GH13_47 α-amylase from Rhodothermus marinus2024
- Author(s)
  Miyasaka, Y., Yokoyama, K., Kozono, T., Kitano, Y., Miyazaki, T., Sakaguchi, M., Nishikawa, A., Tonozuka, T.
- Journal Title
  
  Proteins
  
  Volume: 0 Issue: 8 Pages: 1-14
- DOI
  10.1002/prot.26695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14511, KAKENHI-PROJECT-23K05039
[Journal Article] Jaw1/LRMP is associated with the maintenance of Golgi ribbon structure2023
- Author(s)
  Okumura Wataru、Tadahira Kazuko、Kozono Takuma、Tamura-Nakano Miwa、Sato Hiroyuki、Matsui Hitomi、Dohi Taeko、Rohrer Jack、Tonozuka Takashi、Nishikawa Atsushi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 5 Pages: 383-392
- DOI
  10.1093/jb/mvad004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14801
[Journal Article] Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors2023
- Author(s)
  Kozono Takuma、Jogano Chifuyu、Okumura Wataru、Sato Hiroyuki、Matsui Hitomi、Takagi Tsubasa、Okumura Nobuaki、Takao Toshifumi、Tonozuka Takashi、Nishikawa Atsushi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 136 Issue: 4
- DOI
  10.1242/jcs.260439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14801
[Journal Article] Jaw1/LRMP increases Ca2+ influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype2022
- Author(s)
  Okumura Wataru、Kozono Takuma、Sato Hiroyuki、Matsui Hitomi、Takagi Tsubasa、Tonozuka Takashi、Nishikawa Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 9476-9476
- DOI
  10.1038/s41598-022-13620-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14801
[Journal Article] Enzymatic and structural characterization of β-fructofuranosidase from the honeybee gut bacterium Frischella perrara2022
- Author(s)
  Kubota, A., Kawai, R., Li, D., Kozono, T., Sasaki, N., Nishikawa, A., Fujii, T., Tochio, T., Tonozuka, T.
- Journal Title
  
  Appl. Microbiol. Biotechnol.
  
  Volume: 106 Issue: 7 Pages: 2455-2470
- DOI
  10.1007/s00253-022-11863-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05956, KAKENHI-PROJECT-21K14801
[Journal Article] Structural basis for proteolytic processing of Aspergillus sojae α-glucosidase L with strong transglucosylation activity2022
- Author(s)
  Ding Yifu、Oyagi Ayako、Miyasaka Yuki、Kozono Takuma、Sasaki Nobumitsu、Kojima Yuka、Yoshida Makoto、Matsumoto Yuji、Yasutake Nozomu、Nishikawa Atsushi、Tonozuka Takashi
- Journal Title
  
  Journal of Structural Biology
  
  Volume: 214 Issue: 3 Pages: 107874-107874
- DOI
  10.1016/j.jsb.2022.107874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05956, KAKENHI-PROJECT-21K14801
[Journal Article] Novel protocol to observe the intestinal tuft cell using transmission electron microscopy2022
- Author(s)
  Kozono Takuma、Tamura-Nakano Miwa、Kawamura Yuki I.、Tonozuka Takashi、Nishikawa Atsushi
- Journal Title
  
  Biology Open
  
  Volume: 11 Issue: 2
- DOI
  10.1242/bio.059007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14801, KAKENHI-PROJECT-22K08273
[Presentation] Comprehensive EM imaging of tuft cells in the gastric SCJ using an ultra-wide field montage system2024
- Author(s)
  Marielle Fernandez Bandalan, Takuma Kozono, Takashi Tonozuka, Atsushi Nishikawa
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K14511
[Presentation] Jaw1のCa2+シグナリング増強における機能ドメインの解析2023
- Author(s)
  佐藤展之、小薗拓馬、松本崇、佐藤孝、長谷川智一、神田浩幸、殿塚隆史、西河淳．
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K14511
[Presentation] 小腸上皮タフト細胞におけるJaw1の機能解析と寄生虫感染応答機構の理解の深化2022
- Author(s)
  小薗拓馬、佐藤展之、中野（田村）美和、岡村匡史、中野堅太、奥村航、石渡賢治、河村由紀、殿塚隆史、西河淳
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K14801
[Presentation] Jaw1のC末端切断修飾の切断部位と酵素の同定2022
- Author(s)
  小薗拓馬、城ヶ野千冬、奥村航、佐藤展之、奥村宣明、高尾敏文、殿塚隆史、西河淳
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-21K14801
[Presentation] Jaw1はITPRsとの相互作用を介して細胞内Ca2+シグナルの振幅を制御する2022
- Author(s)
  奥村航、松井仁美、小薗拓馬、佐藤展之、高木翼、殿塚隆史、西河淳
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-21K14801

1. TONOZUKA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KOZONO TAKUMA 小薗 拓馬

KOZONO Takuma 小薗 拓馬

Research Projects

Research Products

Co-Researchers

Molecular mechanism of the helminth expulsion by small intestinal epithelial tuft cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of salt taste perception by a novel subpopulation of taste bud cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Jaw1 accelerates the reaction speed of the Ca2+ signals via ITPRs upon GPCR stimulation2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis for the recognition of α-1,6-branched α-glucan by GH13_47 α-amylase from Rhodothermus marinus2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Jaw1/LRMP is associated with the maintenance of Golgi ribbon structure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Jaw1/LRMP increases Ca2+ influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enzymatic and structural characterization of β-fructofuranosidase from the honeybee gut bacterium Frischella perrara2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis for proteolytic processing of Aspergillus sojae α-glucosidase L with strong transglucosylation activity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel protocol to observe the intestinal tuft cell using transmission electron microscopy2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Comprehensive EM imaging of tuft cells in the gastric SCJ using an ultra-wide field montage system2024

Author(s)

Organizer

Data Source

[Presentation] Jaw1のCa2+シグナリング増強における機能ドメインの解析2023

Author(s)

Organizer

Data Source

[Presentation] 小腸上皮タフト細胞におけるJaw1の機能解析と寄生虫感染応答機構の理解の深化2022

Author(s)

Organizer

Data Source

[Presentation] Jaw1のC末端切断修飾の切断部位と酵素の同定2022

Author(s)

Organizer

Data Source

[Presentation] Jaw1はITPRsとの相互作用を介して細胞内Ca2+シグナルの振幅を制御する2022

Author(s)

Organizer

Data Source

KOZONO TAKUMA 小薗拓馬

KOZONO Takuma 小薗拓馬