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Hisamatsu Daisuke  久松 大介

ORCIDConnect your ORCID iD *help
Researcher Number 20880272
Other IDs
Affiliation (Current) 2025: 順天堂大学, 大学院医学研究科, 特任研究員
Affiliation (based on the past Project Information) *help 2021 – 2024: 順天堂大学, 大学院医学研究科, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 38020:Applied microbiology-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 59020:Sports sciences-related
Keywords
Principal Investigator
免疫ホメオスタシス / メタボローム / マイクロバイオーム / 老化 / i-GONAD / 中枢神経系疾患 / エピジェネティックランドスケープ / トランスクリプトーム解析 / 大うつ病性障害 / エピジェネティック制御 … More / rejuvenation / エピジェネティクス / 神経新生 / 神経幹・前駆細胞 … More
Except Principal Investigator
フレイル / 臓器連関 / Meatbud / バイオリアクター / 中胚葉オルガノイド / サルコペニア / 筋オルガノイド / 多能性幹細胞 / セクレトーム / デザイナーズオルガノイド / 組織幹細胞 / MSCs / 炎症性疾患 / 三次元培養 / オルガノイド Less
  • Research Projects

    (3 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (4 People)
  •  加齢に伴う免疫ホメオスタシス低下に寄与する腸内細菌代謝産物の同定Principal Investigator

    • Principal Investigator
      久松 大介
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 38020:Applied microbiology-related
    • Research Institution
      Juntendo University
  •  Development of Motor Improvement and Novel Therapies through Functional Mesodermal Organoid Transplantation

    • Principal Investigator
      Akazawa Chihiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Juntendo University
  •  新規モデルマウスによる神経発達症のエピゲノム変化の解明Principal Investigator

    • Principal Investigator
      久松 大介
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Juntendo University

All 2024 2023 2022 2021

All Journal Article Presentation Patent

  • [Journal Article] Quality Control of Stem Cell-Based Cultured Meat According to Specific Differentiation Abilities2024

    • Author(s)
      Naraoka Yuna、Mabuchi Yo、Kiuchi Mai、Kumagai Kyoko、Hisamatsu Daisuke、Yoneyama Yosuke、Takebe Takanori、Akazawa Chihiro
    • Journal Title

      Cells

      Volume: 13 Issue: 2 Pages: 135-135

    • DOI

      10.3390/cells13020135

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-21H03328
  • [Journal Article] Activated mesenchymal stem/stromal cells promote myeloid cell differentiation via CCL2/CCR2 signaling2024

    • Author(s)
      Yamazaki Satoshi、Mabuchi Yo、Kimura Takaharu、Suto Eriko Grace、Hisamatsu Daisuke、Naraoka Yuna、Kondo Ayako、Azuma Yuzuki、Kikuchi Riko、Nishikii Hidekazu、Morishita Soji、Araki Marito、Komatsu Norio、Akazawa Chihiro
    • Journal Title

      Stem Cell Reports

      Volume: 19 Issue: 3 Pages: 414-425

    • DOI

      10.1016/j.stemcr.2024.02.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-23K21401, KAKENHI-PROJECT-21H03328
  • [Journal Article] Conservation of Markers and Stemness in Adipose Stem and Progenitor Cells between Cattle and Other Species2023

    • Author(s)
      Ishida Yuki、Mabuchi Yo、Naraoka Yuna、Hisamatsu Daisuke、Akazawa Chihiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 15 Pages: 11908-11908

    • DOI

      10.3390/ijms241511908

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-21H03328
  • [Journal Article] CD73-Positive Cell Spheroid Transplantation Attenuates Colonic Atrophy2023

    • Author(s)
      Hisamatsu Daisuke、Itakura Natsumi、Mabuchi Yo、Ozaki Rion、Suto Eriko Grace、Naraoka Yuna、Ikeda Akari、Ito Lisa、Akazawa Chihiro
    • Journal Title

      Pharmaceutics

      Volume: 15 Issue: 3 Pages: 845-845

    • DOI

      10.3390/pharmaceutics15030845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-18KK0449
  • [Journal Article] Connection between drug-mediated neurotransmission and salivary microbiome2023

    • Author(s)
      Hisamatsu Daisuke、Ogata Yusuke、Takeshige-Amano Haruka、Suda Wataru、Hatano Taku、Asaoka Daisuke、Mabuchi Yo、Naraoka Yuna、Sato Nobuhiro、Asada Takashi、Hattori Nobutaka、Hattori Masahira、Akazawa Chihiro
    • Journal Title

      bioRxiv

      Volume: 2023.08.20.553896 Pages: 1-33

    • DOI

      10.1101/2023.08.20.553896

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Journal Article] Longitudinal Analyses after COVID-19 Recovery or Prolonged Infection Reveal Unique Immunological Signatures after Repeated Vaccinations2022

    • Author(s)
      Hisamatsu Daisuke、Ikeda Akari、Ito Lisa、Matsushita Yasushi、Hiki Makoto、Mori Hirotake、Tabe Yoko、Naito Toshio、Akazawa Chihiro
    • Journal Title

      Vaccines

      Volume: 10 Issue: 11 Pages: 1815-1815

    • DOI

      10.3390/vaccines10111815

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-21H03328
  • [Journal Article] Isolation and Characterization of Tissue Resident CD29-Positive Progenitor Cells in Livestock to Generate a Three-Dimensional Meat Bud2021

    • Author(s)
      Naraoka Yuna、Mabuchi Yo、Yoneyama Yosuke、Suto Eriko Grace、Hisamatsu Daisuke、Ikeda Mami、Ito Risa、Nakamura Tetsuya、Takebe Takanori、Akazawa Chihiro
    • Journal Title

      Cells

      Volume: 10 Issue: 9 Pages: 2499-2499

    • DOI

      10.3390/cells10092499

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-21H04822
  • [Patent] 神経変性疾患及び前駆障害の判定方法及び判定装置2024

    • Inventor(s)
      久松大介、赤澤智宏
    • Industrial Property Rights Holder
      学校法人 順天堂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2024-042370
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Patent] 神経変性疾患のリスク判定方法及び判定装置2023

    • Inventor(s)
      赤澤智宏、久松大介、服部正平、服部信孝、須田亙、緒方勇亮、朝田隆
    • Industrial Property Rights Holder
      学校法人 順天堂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-556884
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Patent] 中枢神経系用薬服用の評価のための方法および装置2023

    • Inventor(s)
      赤澤智宏, 久松大介, 服部正平
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-132501
    • Filing Date
      2023
    • Acquisition Date
      2023
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Patent] 中枢神経系用薬服用の評価のための方法および装置2023

    • Inventor(s)
      赤澤智宏、久松大介、服部正平
    • Industrial Property Rights Holder
      学校法人 順天堂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-132501
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Patent] 神経変性疾患のリスク判定法2022

    • Inventor(s)
      赤澤智宏、久松大介、服部正平、服部信孝、須田亙、緒方勇亮
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-149488
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Patent] 神経変性疾患のリスク判定法2022

    • Inventor(s)
      久松大介、赤澤智宏、服部正平、服部信孝、須田亙、緒方勇亮、朝田隆
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-149488
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Patent] キメラ中和抗体及びその製造方法2021

    • Inventor(s)
      久松大介、赤澤智宏
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-198896
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Patent] 新型コロナウイルス中和抗体又はその機能的断片2021

    • Inventor(s)
      久松大介、赤澤智宏
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-033681
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Patent] 新型コロナウイルス中和抗体又はその機能的断片2021

    • Inventor(s)
      久松大介、赤澤智宏
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-033681
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Patent] キメラ中和抗体及びその製造方法2021

    • Inventor(s)
      久松大介、赤澤智宏
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-198896
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Presentation] CD73陽性細胞の経腸移植が大腸炎に与える影響2023

    • Author(s)
      池羽輝海, 久松大介, 馬渕洋, 赤澤智宏
    • Organizer
      第44回 日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Presentation] A new conceptual model for antibody generation based on convalescent sera-derived synthetic chimeric antibody with enhanced diversity2023

    • Author(s)
      Hisamatsu D, Akazawa C
    • Organizer
      Cell Symposia The conceptual power of single cell biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Presentation] A new conceptual model for antibody generation based on convalescent sera-derived synthetic chimeric antibody with enhanced diversity2023

    • Author(s)
      Hisamatsu D, Akazawa C
    • Organizer
      Cell Symposia The conceptual power of single cell biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Presentation] CD73陽性細胞の経腸移植が大腸炎に与える影響2023

    • Author(s)
      池羽輝海, 久松大介, 馬渕洋, 赤澤智宏
    • Organizer
      第44回 日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Presentation] 再生医療に向けたヒト脂肪組織由来CD73陽性細胞の品質評価2023

    • Author(s)
      大和拓, 久松大介, 馬渕洋, 赤澤智宏
    • Organizer
      第44回 日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21K15888
  • [Presentation] 再生医療に向けたヒト脂肪組織由来CD73陽性細胞の品質評価2023

    • Author(s)
      大和拓, 久松大介, 馬渕洋, 赤澤智宏
    • Organizer
      第44回 日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21H03328
  • [Presentation] Precision diagnosis of neurodegenerative diseases based on salivary microbiome profiles2022

    • Author(s)
      Daisuke Hisamatsu
    • Organizer
      IHMC(INTERNATIONAL HUMAN MICROBIOME CONSORTIUM) 9th CONGRESS 2022 KOBE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15888
  • 1.  Akazawa Chihiro (80291160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  馬渕 洋 (50424172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  奈良岡 佑南 (50828522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  須藤 絵里子グレース
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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